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Journal articles on the topic 'Prolong fever'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Nur, Nadilla Cynthia. "The Effectivity Of Water Tepid Sponge Therapy In Overcoming Nursing Problem Of Hyperthermia In Pediatric With Prolong Fever: A Case Study." International Journal of Nursing and Midwifery Research 2, no. 1 (2023): 24–28. https://doi.org/10.35335/ners.v2i1.110.

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One of the most common symptoms that bring patients to health services is fever. Prolong fever is a condition where the child's body is at a body temperature of more than 380C which occurs for approximately 8 days. Improper and slow handling of prolong fever will effect febrile seizures, dehydration, fainting, persistent high fever which causes brain damage. This study aimed to determine the effectiveness of the water tepid sponge intervention in overcoming nursing problem of hyperthermia in pediatric with prolong fever. The research method used is a case study with a nursing process approach

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Khin, Phyu Pyar, Aung Aung, Bo Thek Soe, et al. "Prolong Fever in Elderly Man with Anemia, Lymphopenia, Thrombocytopenia, Ascites, Hypoalbuminemia, Hepatitis and Renal Failure Following Prostate Surgery: Emerging Invasive Fungal Infections By Candida Albicans, Sepedonium Species and Candida Tropicalis." International Journal of Medical Science and Clinical Research Studies 5, no. 05 (2025): 770–86. https://doi.org/10.5281/zenodo.15515672.

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A 78-years-old male had fever for two weeks with appetite loss and weight loss. He had hypertension and chronic kidney disease. He underwent transurethral resection of prostate one month ago for benign prostatic hypertrophy. It was complicated by urinary tract infection due to Klebsiella pneumoniae two months prior to fever. Physical examination was unremarkable except mild anemia. Blood examination revealed anemia, lymphopenia, thrombocytopenia, transaminitis, high serum creatinine and high inflammatory markers (ESR, CRP and procalcitonin). Studies on imaging (chest radiograph, CT scan chest,

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Villafuerte-Gutierrez, Paola, Lucia Villalon, Juan E. Losa, and Cesar Henriquez-Camacho. "Treatment of Febrile Neutropenia and Prophylaxis in Hematologic Malignancies: A Critical Review and Update." Advances in Hematology 2014 (2014): 1–9. http://dx.doi.org/10.1155/2014/986938.

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Febrile neutropenia is one of the most serious complications in patients with haematological malignancies and chemotherapy. A prompt identification of infection and empirical antibiotic therapy can prolong survival. This paper reviews the guidelines about febrile neutropenia in the setting of hematologic malignancies, providing an overview of the definition of fever and neutropenia, and categories of risk assessment, management of infections, and prophylaxis.

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Faisal, Ferdous Mahmud, Sudip Das Gupta, Nazrul Islam Mridha, Mohammad Mahfuzur Rahma, Ibne Safi Abdul Ahad, and Shamsun Nahar. "Comparative Study between Initial Positive and Negative Preoperative Urine Culture for Postoperative Fever in PCNL Patients." Bangladesh Journal of Urology 24, no. 1 (2022): 25–32. http://dx.doi.org/10.3329/bju.v24i1.59440.

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Background: The exact mechanism of fever after PCNL has not been established.2. This research studied the frequency of post-PCNL fever and UTI in both initial preoperative positive and negative urine culture group of patients. Objectives: To compare the frequency of post PCNL fever and UTI in initial positive and negative preoperative urine culture patients. Method: This was a prospective observational study on a total sixty patients who underwent single PCNL at the Department of Urology, Sir Salimullah Medical College Mitford Hospital, Dhaka and National Institute of Kidney Diseases and Urolo

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Faisal, Ferdous Mahmud, Sudip Das Gupta, Nazrul Islam Mridha, Mohammad Mahfuzur Rahma, Ibne Safi Abdul Ahad, and Shamsun Nahar. "Comparative Study between Initial Positive and Negative Preoperative Urine Culture for Postoperative Fever in PCNL Patients." Bangladesh Journal of Urology 24, no. 1 (2022): 25–32. http://dx.doi.org/10.3329/bju.v24i1.59440.

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Background: The exact mechanism of fever after PCNL has not been established.2. This research studied the frequency of post-PCNL fever and UTI in both initial preoperative positive and negative urine culture group of patients. Objectives: To compare the frequency of post PCNL fever and UTI in initial positive and negative preoperative urine culture patients. Method: This was a prospective observational study on a total sixty patients who underwent single PCNL at the Department of Urology, Sir Salimullah Medical College Mitford Hospital, Dhaka and National Institute of Kidney Diseases and Urolo

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Kabir, Ahmedul, Aparna Das, Mahmudul Hassan Banna, Baharul Minnat, and H. A. M. Nazmul Ahasan. "Splenic Tuberculosis: A Cause of Pyrexia of Unknown Origin Report of Two Cases." Journal of Medicine 14, no. 1 (2013): 88–90. http://dx.doi.org/10.3329/jom.v14i1.14586.

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Tuberculosis of spleen is an extremely rare clinical entity. It often poses diagnostic difficulties as microbiological confirmation of diagnosis is not easy. We encountered two casas who presented with prolong fever but no other symptoms. Laboratory data provided no specific information for diagnosis. Abdominal ultrasonography revealed splenomegaly with multiple small hypoechoic lesions within the spleen. A diagnosis of isolated splenic tuberculosis was confirmed after a splenic puncture and histopathological examination.DOI: http://dx.doi.org/10.3329/jom.v14i1.14586 J MEDICINE 2013; 14 : 88-9

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Huang, I‐Fei, Marilyn M. Wagener, Kai‐Sheng Hsieh, et al. "Nontyphoid Salmonellosis in Taiwan Children: Clinical Manifestations, Outcome and Antibiotic Resistance." Journal of Pediatric Gastroenterology and Nutrition 38, no. 5 (2004): 518–23. http://dx.doi.org/10.1002/j.1536-4801.2004.tb12213.x.

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ABSTRACTObjectives:The purposes of this study were to investigate the epidemiologic, clinical, and microbiologic features of patients with nontyphoid salmonellosis and to elucidate the impact of resistance on the outcome of nontyphoid salmonellosis in Taiwan. The authors also sought to develop a severity score to derive an objective guideline for antibiotic use in nontyphoid salmonellosis in the era of increasing antibiotic resistance.Methods:The authors prospectively monitored 311 children with nontyphoid salmonellosis in Kaohsiung, Taiwan. The demographic, clinical, and microbiologic feature

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Rishad, Mahbub Mayukh, Sumaiya Akter, and Mohammad Zahiruddin. "A Middle Aged Man Presented with Prolonged Fever and Low Back Pain Diagnosed as Brucellosis." Bangladesh Journal of Medicine 33, no. 1 (2021): 89–93. http://dx.doi.org/10.3329/bjm.v33i1.56796.

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Brucellosis is a Zoonotic disease which is not so common health problem in Bangladesh. For its variable presentation it creates diagnostic challenge for the clinicians. Although Brucellosis is a treatable and curable condition sometimes delay in diagnosis and lack of insight for the disease creates high morbidity. In this case report we have presented a case of brucellosis presented with prolong fever, joint pain with complications which created dilemma in diagnosis in a tertiary care private hospital of Dhaka. The purpose of presenting this case report is to create concern among the clinician

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Alam, Dilruba, Rumana Habib, Mahir Muhtasim, and Md Rezwanul Haque. "Brain abscess complicating a diabetic man with Evans syndrome: a case report." BIRDEM Medical Journal 11, no. 2 (2021): 137–41. http://dx.doi.org/10.3329/birdem.v11i2.53136.

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Brain abscess is a relatively rare but potentially life threatening condition. The classic clinical triad of fever, headache and focal neurological sign may not be present in an immuno-compromised patient. The diagnostic delay may result in fatal outcome. A 52-year-old diabetic gentleman with history of chronic immunosuppressive therapy due to Evans syndrome presented with headache, generalized tonic- clonic seizure and right upper limb monoparesis. Clinical ground and neuroimaging was suggestive of pyogenic brain abscess. Patient was treated with antibiotic therapy for prolong period and ther

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Shendi, Hiba M., Deirdre Walsh, and J. David M. Edgar. "Etanercept and anakinra can prolong febrile episodes in patients with hyperimmunoglobulin D and periodic fever syndrome." Rheumatology International 32, no. 1 (2009): 249–51. http://dx.doi.org/10.1007/s00296-009-1322-8.

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Aghaei Moghadam, Ehsan, Nahid Aslani, Helia Mojtabavi, Farnoosh Larti, Azin Ghamari, and Vahid Ziaee. "Giant Thrombosis at Left Anterior Descending Artery Aneurysm in a 10-Year Old Boy with Granulomatosis with Polyangiitis." Case Reports in Cardiology 2020 (April 22, 2020): 1–5. http://dx.doi.org/10.1155/2020/3417910.

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Granulomatosis with polyangiitis (GPA), necrotizing vasculitis of small and medium-sized vessels, is traditionally believed to mainly affect respiratory tract with additional focal kidney involvements as its primary manifestations with a relatively rare annual incidence rate of 20-50 cases per million. Six percent of the affected cases have cardiac involvements; among which, aneurysms comprise the lowest penetrance. By this paper, we aim to cast light on clinical diagnostic and treatment methods of a rare case presentation, a 10-year-old male GPA patient, diagnosed with massive thrombosis at h

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Drew, D., A. Baranchuk, and R. J. Brison. "P037: The impact of fever on corrected QT interval in a general emergency department population." CJEM 18, S1 (2016): S90—S91. http://dx.doi.org/10.1017/cem.2016.213.

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Introduction: Fever is one of the most common reasons for presentation to the emergency department (ED). Interestingly, a number of small studies suggest that fever may function as a modulator of the QT interval in healthy individuals and an arrhythmogenic trigger in patients with occult congenital QT abnormalities. The objective of this study was to explore whether presence of fever adversely affects the QT interval, and whether medications known to prolong this interval affect any association found. Methods: We performed a retrospective, single center study identifying patients (age > 18

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Rao, Farah, Waheed Ahmed, Zaboor Ahmed, Syed Haider Tirmizi, Muhammad Usman Khan, and Farhan Tariq. "FREQUENCY OF SUPERIMPOSED BACTERIAL INFECTIONS IN PATIENTS PRESENTING WITH DENGUE FEVER." Insights-Journal of Health and Rehabilitation 3, no. 3 (Health & Rehabilitation) (2025): 55–60. https://doi.org/10.71000/24b0s754.

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Background: Dengue fever is a significant public health challenge in endemic regions, often complicated by secondary bacterial infections which increase the severity and prolong hospitalization. These co-infections not only raise morbidity and mortality rates but also strain healthcare systems, especially during seasonal outbreaks. Early identification of such infections using laboratory markers is critical to improving clinical outcomes and guiding appropriate treatment strategies in resource-limited settings. Objective: To determine the frequency of superimposed bacterial infections among pa

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Garbuio, Matheus, Larissa Marila de Souza, Lucas Danilo Dias, et al. "Curcumin Microcapsule Formulations for Prolong Persistence in the Photodynamic Inactivation of Aedes aegypti Larvae." Pharmaceutics 17, no. 4 (2025): 496. https://doi.org/10.3390/pharmaceutics17040496.

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Background: Viral diseases including dengue, zika, chikungunya, and yellow fever remain a significant public health challenge, primarily due to the increasing resistance of these vectors, the Aedes aegypti mosquito, to conventional control methods. Objectives: Herein, a microencapsulated curcumin formulation was developed and characterized using spray-drying technology, with D-mannitol and starch as encapsulating agents. After microencapsulation, photolarvicidal tablet formulations (Formulated Curcumin Tablets—FCT) were prepared, varying the proportions of starch and pectin: FCT1 (60% starch),

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Khaniya, Bishal. "Fetomaternal Outcome in Second Stage Caesarean Section." Nepalese Medical Journal 3, no. 1 (2020): 279–81. http://dx.doi.org/10.3126/nmj.v3i1.28923.

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Introduction: Second stage caesarean section is usually associated with the deeply engaged head, less liquor, and thinned out the lower uterine segment. This can lead to a high risk of maternal morbidities like an extension of the lower uterine segment incision, uterine atony, and injury to urinary bladder as well as neonatal morbidities such as birth asphyxia, NICU admission, and meconium aspiration syndrome. This study aims to observe the maternal and neonatal outcomes of caesarean delivery performed in the second stage of labor. Materials and Methods: This was a retrospective study of

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Nadhiroh, Siti Rahayu, Anisa Lailatul Fitria, Armedy Ronny Hasugian, et al. "Body mass index as the main predictor for length of stay in COVID-19 patients with mild and moderate symptoms: a cross-sectional study in COVID-19 emergency hospital in Indonesia." Jurnal Ners 19, no. 2 (2024): 165–72. http://dx.doi.org/10.20473/jn.v19i2.53973.

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Introduction: COVID-19 emerged as a novel global health crisis. While it has since been downgraded from its status as a public health emergency of international concern, the virus persists as a global health challenge. This study was aimed to analyze the predictors of LoS in COVID-19 patients based on nutritional status and patient characteristics data. Methods: Participants of this study were the COVID-19 patients with mild to moderate symptoms who registered in COVID-19 Emergency Hospital, East Java, Indonesia. This study involved 2850 patients extracted from medical records for further anal

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17

Xu, Hua, Yongchun Deng, Zhi Zhou, and Yi Huang. "Chinese Herbal Medicine (Chaihu-Huaji Decoction) Alleviates Postembolization Syndrome following Transcatheter Arterial Chemoembolization and Improves Survival in Unresectable Hepatocellular Cancer: A Retrospective Study." Evidence-Based Complementary and Alternative Medicine 2019 (February 3, 2019): 1–6. http://dx.doi.org/10.1155/2019/6269518.

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Objective. To examine the efficacy of Chaihu-huaji decoction combined with transarterial chemoembolization (TACE) in unresectable hepatocellular carcinoma (HCC) patients. Methods. We retrospectively reviewed the data of 125 HCC patients treated in Chongqing Cancer Hospital between January 2012 and December 2014, including 64 patients who received Chaihu-huaji decoction and TACE (Chaihu-huaji group) and 61 patients who received only TACE (control group). The patients were examined until the last follow-up or death. Complications, hepatotoxicity, and nephrotoxicity were compared between the two

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Lee, Tae Gyeong, Soomin Nam, Hyung Soon Lee, Jin Ho Lee, Young Ki Hong, and Jung Gu Kang. "Irrigation Versus Suction Alone During Laparoscopic Appendectomy for Uncomplicated Acute Appendicitis." Annals of Coloproctology 36, no. 1 (2020): 30–34. http://dx.doi.org/10.3393/ac.2019.06.25.

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Purpose: To compare the surgical outcomes of peritoneal irrigation versus suction alone during laparoscopic appendectomy and to identify the risk factors of surgical site infection in patients with uncomplicated acute appendicitis.Methods: Data from patients with uncomplicated acute appendicitis between January 2014 and March 2016 were reviewed. We compared the irrigation and suction alone groups with regard to the following parameters: postoperative complication incidence rate, length of hospital stay, operation time, time to flatus, time to diet commencement, and duration of postoperative an

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Harikarnpakdee, Saraporn, and Chomnapas Chuchote. "Oviposition Deterrent Efficacy and Characteristics of a Botanical Natural Product,Ocimum gratissimum(L.) Oil-Alginate Beads, againstAedes aegypti(L.)." Scientific World Journal 2018 (August 1, 2018): 1–9. http://dx.doi.org/10.1155/2018/3127214.

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This study was aimed at investigating the oviposition deterrent activity ofOcimum gratissimum(L.) essential oil (O. gratissimumoil) and its product,Ocimum gratissimum(L.)- alginate beads (beads), againstAedes aegypti(Ae. aegypti) mosquitoes. Chemical analysis ofO. gratissimumoil obtained by hydrodistillation, using gas chromatography-mass spectroscopy techniques, presented eugenol (67.38%) and Z-β-ocimene (14.95 %) as major constituents. Good characteristics of beads were obtained by the orifice-ionic gelation method with calcium chloride as hardening agent and Tween®20 as emulsifier. The bead

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Martin, David E., and Ralph H. Raasch. "Rifabutin: A New Rifamycin for the Prevention of Atypical Mycobacterial Infection." Journal of Pharmacy Technology 10, no. 5 (1994): 197–203. http://dx.doi.org/10.1177/875512259401000503.

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Objective: To discuss the chemistry, mechanism of action, in vitro activity, pharmacology, clinical efficacy, and toxicity of rifabutin, a new rifamycin, in the prevention and treatment of disseminated mycobacterial infection in patients with AIDS. Data Sources: The English-language literature was searched from 1980 through October 1993 using MEDLINE, International Pharmaceutical Abstracts (IPA), Index Medicus, and bibliographic reviews of relevant textbooks and review articles. Study Selection: One published report of two identical randomized, prospective, double-blind trials of rifabutin to

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Liu, Jian, Peng Jing, Feng Gao, et al. "Observation on the clinical effect and survival period of patients with esophageal cancer treated with UMIPIC combined with low dose radiotherapy." Journal of Clinical Oncology 38, no. 15_suppl (2020): e16517-e16517. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e16517.

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e16517 Background: To observe the clinical effect and survival period of UMIPIC (ultra-minimum incision personalized intratuoral chemoimmunotherapy) combined with radiotherapy in the treatment of esophageal cancer. Methods: 712 patients with esophageal cancer who received UMIPIC treatment in our hospital from January 2011 to December 2015 were selected for the study subjects, 540 cases were treated by UMIPIC combination with radiotherapy in group A and 172 cases were treated by UMIPIC without radiotherapy in group B. All patients were diagnosed with esophageal cancer, and signed the consent fo

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., Isha, Prabha Lal, Vikram Dutta, and Aayushi Kaushal. "A prospective observational study of fetomaternal outcome in second stage caesarean section." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 8, no. 12 (2019): 4798. http://dx.doi.org/10.18203/2320-1770.ijrcog20195323.

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Background: Incidence of caesarean section is rapidly rising over last two decades and one fourth is contributed by caesarean section in second stage. The objective of this study was to study of fetomaternal outcome in second stage caesarean section.Methods: Prospective observational study was done in 80 women undergoing second stage caesarean section from December 2015 to March 2017 at Lady Hardinge Medical Collage Delhi. These women observed from labour to caesarean section in second stage of labour till post-operative period for any complication. Intraoperative and postoperative complicatio

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Mossa, J. S., M. Tariq, A. Mohsin, et al. "Pharmacological Studies on Aerial Parts of Calotropis Procera." American Journal of Chinese Medicine 19, no. 03n04 (1991): 223–31. http://dx.doi.org/10.1142/s0192415x91000302.

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The decoction of the aerial part of Calotropis procera is commonly used in Saudi Arabian traditional medicine for the treatment of variety of diseases including fever, joint pain, muscular spasm and constipation. The present investigation was undertaken to confirm its claimed activity in traditional medicine. The ethanol extract of the plant was tested on laboratory animals for its antipyretic, analgesic, anti-inflammatory, antibacterial, purgative and muscle relaxant activities. The results of this study showed a significant antipyretic, analgesic and neuromuscular blocking activity. On smoot

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Pathak, R., S. Harsh, A. Adhikari, and PK Khadga. "Clinical Spectrum of Spontaneous Bacterial Peritonitis in Tertiary Care Centre." Journal of Institute of Medicine Nepal 35, no. 3 (2024): 41–43. http://dx.doi.org/10.59779/jiomnepal.654.

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Introduction: Cirrhosis is a common diagnosis in the inpatient population seeking care at the gastroenterology department of the Institute Of Medicine. Spontaneous Bacterial Peritonitis (SBP) is commonly associated with decompensated liver cirrhosis and has been associated with frequent adverse outcome. This small study was designed to spectrum of disease and profile of patient having Spontaneous Bacterial Peritonitis. Methods: The retrospective study was conducted in patient admitted in department of gastroenterology. A total of 51 patients suffering from cirrhosis with ascites was studied. A

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He, Ping, Fangqi Hu, and Fei Wang. "A study of the relationship between cough and wheezing complicated by common respiratory viral infections in infants and secondary thrombocythemia." PLOS One 20, no. 7 (2025): e0326369. https://doi.org/10.1371/journal.pone.0326369.

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Objective To explore the relationship between respiratory viral infections complicated by cough and wheezing and the clinical features of thrombocythemia in infants. Methods We retrospectively analyzed the clinical data of 200 infants with fever, cough and wheezing who were admitted to the Department of Pediatrics of Anqing Municipal Hospital between January 2023 and October 2024. Respiratory viruses were detected using real-time PCR to screen for virus-positive infants. Infants were classified into the thrombocythemia group (ST group) and the non-thrombocythemia group (non-ST group) based on

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Pooja, Jain, Vimal Gupta Rekha, and Sanodia Geetanjali. "Evaluation of Risk Factors & Maternal and Perinatal Outcome in Puerperal Pyrexia: A Prospective Study." International Journal of Pharmaceutical and Clinical Research 15, no. 5 (2023): 325–29. https://doi.org/10.5281/zenodo.12553994.

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<strong>Background & Method:</strong> The present study is conducted with an aim to Evaluate risk factors & maternal and perinatal outcome in Puerperal Pyrexia – A Prospective Observational Study carried out in the department of Obstetrics and Gynaecology at Government Medical College Ratlam. Prolonged labour, caesarean section, wound infection, septicemia, UTI, endometritis are the most common etiology and risk factors of puerperal pyrexia globally and Indian studies which ranged between 4 to 80%. Therefore, we considered 20% probability of risk factors with 6.4% marginal e

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Nurkholis, Fathur, Banteng Hanang Wibisono, Agus Suryanto, Thomas Handoyo, Farida Farida, and Jimmy Tanamas. "Factors Influencing the Delay in Negative Conversion of PCR Swab Test Results in Patients with COVID-19." Medica Hospitalia : Journal of Clinical Medicine 9, no. 2 (2022): 199–206. http://dx.doi.org/10.36408/mhjcm.v9i2.755.

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Background : The negative conversion duration of SARS-CoV-2 RNA was related to disease progression, and a prolonged negative conversion could provide early warning signal for poor prognosis in patients with COVID-19. The objectives of this study was to identify the factors influencing the delay in negative conversion of PCR swab test results in patients with COVID-19 as a consideration in determining the COVID-19 prevention policy in the community Methods : A retrospective cross-sectional study involving 68 patients diagnosed with COVID-19 that was treated in Dr. Kariadi General Hospital Medic

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Cao, Wei, Peng Zhang, Nana Dong, et al. "Efficacy Evaluation of Zoledronic Acid Combined with Chemotherapy in the Treatment of Lung Cancer Spinal Metastases on Computed Tomography Images on Intelligent Algorithms." Computational and Mathematical Methods in Medicine 2022 (May 6, 2022): 1–11. http://dx.doi.org/10.1155/2022/6431852.

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To analyze the effectiveness and safety of zoledronic acid combined with chemotherapy for lung cancer spinal metastases, 96 patients with lung cancer spinal metastases were averagely classified into the experimental group (gemcitabine, cisplatin, and zoledronic acid) and the control group (gemcitabine and cisplatin). An optimized noise variance estimation algorithm (OMAPB) was proposed based on the maximum a posteriori Bayesian method (MAPB), and the algorithm was applied to the patient’s computed tomography (CT) scan. The results indicated that in terms of curative effect, the number of compl

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Wahyutomo, Ridha. "Infective Endocarditis in 60 Years Old Man at Dr. Kariadi Hospital." Sains Medika : Jurnal Kedokteran dan Kesehatan 5, no. 1 (2013): 45. http://dx.doi.org/10.30659/sainsmed.v5i1.365.

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Infective endocarditis is an infection of the lining of the heart, particularly the cusps of valves characterized by fever and heart murmur, with or without malaise and fatigue. Clinical features can be divided into early manifestations of infection, embolic events, and late complications of sepsis and inflammation. It was reported that 60 years old man was brought to Kariadi hospital with prolong febris as his chief complaint. Patient has history of high grade fever and accompanied by weight loss, 3 kilograms for about 2 months. From physical examination result, in internal ward, we found he

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Niu, Jingxiu, Yanjie Ren, Tianyu Zhang, et al. "Retrospective Comparative Study of the Effects of Dendritic Cell Vaccine and Cytokine-Induced Killer Cell Immunotherapy with that of Chemotherapy Alone and in Combination for Colorectal Cancer." BioMed Research International 2014 (2014): 1–7. http://dx.doi.org/10.1155/2014/214727.

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Purpose.This retrospective study determined the delayed-type hypersensitivity (DTH) skin test and safety of dendritic cell (DC) vaccine and cytokine-induced killer (CIK) cell immunotherapy and the survival compared to chemotherapy in 239 colorectal cancer (CRC) patients.Methods.DTH and safety of the immunotherapy were recorded. The overall survival (OS) and disease free survival curves were compared according to the immunotherapy and/or chemotherapy received with Kaplan-Meier estimates.Results.Of the 70 patients who received immunotherapy, 62.86% had a positive DTH skin test, 38.57% developed

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Raval, G. G., and R. Govindarajan. "Efficacy and safety of administration of gemcitabine and docetaxel with radiation therapy in patients with high-grade soft tissue sarcoma." Journal of Clinical Oncology 27, no. 15_suppl (2009): e21503-e21503. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.e21503.

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e21503 Background: Neo-adjuvant therapy of soft tissue sarcoma is not standardized. Anthracyclines (A) improve disease free and overall survival in high grade extremity soft tissue sarcomas measuring more than 5 cm. A and ifosfamide (I) therapy require inpatient administration and is associated with significant toxicities when administered in combination with RT. G in combination with D has been shown to prolong progression free and overall survival in patients with advanced or metastatic STS after progression on A and I, and in patients unable to receive the combination. The safety of adminis

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a Surajsingh Subhash Rajput, Vd Rana, and Vd Parshuram Pawar. "Guduchi (Tinosporacordifolia): A Review Article." International Journal of Pharmaceutical Research and Applications 09, no. 05 (2024): 680–84. https://doi.org/10.35629/4494-0905680684.

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Guduchi of family Menispermaceae. A Sanskrit word meaning "that which protects body from diseases" is guduchi. Another name for this herb is "Amrita," which in Hindu mythology means "the heavenly elixir." The story says that Guduchi kept celestial beings young forever by preventing them from growing old. Because of its many applications and abundance of life energy, it is considered a potential drug in Ayurveda. Long before the era of modern technology, the ancient rishis of the Vedic era recognised its ability to help prolong life. Potentially used extensively to treat fever, diabetes, urogen

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Vicenzi, Elisa, Isabel Pagani, Silvia Ghezzi, et al. "Subverting the mechanisms of cell death: flavivirus manipulation of host cell responses to infection." Biochemical Society Transactions 46, no. 3 (2018): 609–17. http://dx.doi.org/10.1042/bst20170399.

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Viruses exploit host metabolic and defence machinery for their own replication. The flaviviruses, which include Dengue (DENV), Yellow Fever (YFV), Japanese Encephalitis (JEV), West Nile (WNV) and Zika (ZIKV) viruses, infect a broad range of hosts, cells and tissues. Flaviviruses are largely transmitted by mosquito bites and humans are usually incidental, dead-end hosts, with the notable exceptions of YFV, DENV and ZIKV. Infection by flaviviruses elicits cellular responses including cell death via necrosis, pyroptosis (involving inflammation) or apoptosis (which avoids inflammation). Flavivirus

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Bhatnagar, Mohit. "Hypokalemia as a Surrogate Marker of Severity in COVID 19 Infection." Journal of the Endocrine Society 5, Supplement_1 (2021): A489. http://dx.doi.org/10.1210/jendso/bvab048.1000.

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Abstract Introduction: Patients with COVID-19 infection present with a variety of clinical symptoms such as fever, diarrhea, dyspnea, anosmia and various electrolyte abnormalities. Hypokalemia is an important electrolyte abnormality associated with infection due to SARS-CoV-2 as it may be associated with life threatening cardiac abnormalities Objective: To investigate the prevalence and clinical implications of of hypokalemia and its association with disease severity and various laboratory markers of inflammation. Materials and methods-design, setting and participants: This retrospective study

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Batts, Cynthia N. "Adjuvant Intravesical Therapy for Superficial Bladder Cancer." Annals of Pharmacotherapy 26, no. 10 (1992): 1270–76. http://dx.doi.org/10.1177/106002809202601016.

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OBJECTIVE: To review the results of clinical trials and adverse drug effects of thiotepa, BCG vaccine, mitomycin, and doxorubicin, which are used as adjuvant intravesical therapy for superficial bladder cancer. DATA SOURCE: Information was retrieved from a MEDLINE search, of the English-language literature. Indexing terms included adjuvant pharmaceutics, bladder neoplasms, thiotepa, mitomycin, BCG vaccine, and doxorubicin. DATA EXTRACTION: Data from several human and in vitro studies were assessed and evaluated, according to the strength of comparative data and therapeutic response. STUDY SELE

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Gao, Feng, Peng Jing, Jian Liu, et al. "The effect of hapten on the clinical efficacy and survival of patients with liver cancer treated by UMIPIC." Journal of Clinical Oncology 38, no. 15_suppl (2020): e16130-e16130. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e16130.

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e16130 Background: To observe the effect of adjuvant on the clinical efficacy and survival period of patients with liver cancer treated by UMIPIC (Ultra-minimum Incision personalized intratumoral chemoimmunotherapy). Methods: 156 liver cancer patients who were treated with UMIPIC with hapten or without hapten from January 2011 to December 2015 were selected for the study objects, including 124 cases with hapten as studying group and 32 cases without hapten as comparing group. All patients signed the treatment consent, treated according to the treatment guidelines of UMIPIC, followed up for the

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Rashidi, Armin, Maryam Ebadi, Tauseef Ur Rehman, et al. "Circulating Metabolomics Suggest Neutropenic Fever As a Metabolic Derangement Related to Intestinal Tissue Damage and Gut Dysbiosis." Blood 138, Supplement 1 (2021): 688. http://dx.doi.org/10.1182/blood-2021-146644.

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Abstract Introduction: Despite antibiotic prophylaxis, most patients with acute myeloid leukemia (AML) develop neutropenic fever (NF) during intensive chemotherapy, suggesting a non-infectious etiology in many cases. In addition, escalated antibiotics used to treat NF increase the risk of Clostridioides difficile infection, promote pathogen colonization, prolong hospitalization, and increase healthcare costs. More effective prevention of NF, preferably using non-antibiotic approaches, is needed. We hypothesized that a longitudinal analysis of the circulating metabolome may reveal novel aspects

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Nykamp, Diane L., Casey L. Blackmon, Paul E. Schmidt, and Andrea G. Roberson. "QTc Prolongation Associated with Combination Therapy of Levofloxacin, Imipramine, and Fluoxetine." Annals of Pharmacotherapy 39, no. 3 (2005): 543–46. http://dx.doi.org/10.1345/aph.1e513.

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OBJECTIVE: To report QTc interval prolongation associated with combination therapy including levofloxacin, imipramine, and fluoxetine. CASE SUMMARY: A 49-year-old white female presented to the emergency department with fever, aches, and pains for the past 3 days. She was diagnosed and treated for pyelonephritis in the hospital. Therapy included intravenous levofloxacin 500 mg every 24 hours and ceftriaxone 2 g every 24 hours, along with her medications upon admission, including imipramine 50 mg at bedtime and fluoxetine 10 mg/day. She was discharged after 5 days and returned the next day with

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Gurina, E. R., and A. M. Lunegov. "Toxicity of Etopozid in the treatment of cats with lymphoma." Legal regulation in veterinary medicine, no. 2 (July 21, 2023): 84–88. http://dx.doi.org/10.52419/issn2782-6252.2023.2.84.

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Lymphoma in cats is a malignant neoplasm of lymphoid tissue (lymphocytes and other cells of the defense system are affected). Causes of lymphoma in cats can vary, including genetic factors, viruses, and exposure to carcinogens. Most often, patients are admitted to an appointment already with an advanced stage of lymphoma, since the signs of oncological disease are nonspecific and can be easily confused with other diseases of the gastrointestinal tract. Symptoms in cats may include swollen abdominal lymph nodes, decreased appetite and loss of lean body mass, behavioral changes (lethargy, weakne

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Tuladhar, Lujaw Ratna, A. Shrestha, and R. K. Shrestha. "Adverse Drug Reaction with Hyoscine and Valethamate for Cervical Dilation during Labour." Nepal Medical College Journal 21, no. 2 (2019): 128–33. http://dx.doi.org/10.3126/nmcj.v21i2.25112.

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Adverse drug reaction (ADR) is an injury caused by taking medication. ADR may occur following single dose or prolong administration of drug or combination of two or more drugs. While major advancements of discipline of pharmacovigilance have taken place in the West, not much has been achieved in Asian countries. Labour is characterised by forceful and painful uterine contraction that result in cervical dilation and foetus decent from the birth canal. Anti-spasmodic drugs like hyoscine butylbromide and valethamate bromide have been used to accelerate cervical dilation and thus reduce the labor

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Noor, Sidra, Mohammad Ismail, Iqbal Haider, and Faiza Khadim. "Drug-Drug Interactions in Hepatitis Patients: Do these Interactions Matter in Clinical Perspectives?" Annals of Hepatology 17, no. 5 (2018): 0–10. http://dx.doi.org/10.5604/01.3001.0012.2238.

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Introduction and aim. Hepatitis patients usually present with comorbidities and polypharmacy which increases risk of potential drug-drug interactions (pDDIs). We explored frequency, levels, predictors, and clinical relevance of pDDIs in hospitalized hepatitis patients. Methods. Retrospective cohort study was used. Clinical profiles of 413 hepatitis patients were reviewed for pDDIs using Micromedex-DrugReax. Frequency, levels and clinical relevance of pDDIs were reported. Logistic regression analysis was used to calculate odds-ratios for predictors. Results. Of total 413 patients, pDDIs were re

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Maude, Shannon L., David M. Barrett, David E. Ambrose, et al. "Efficacy and Safety of Humanized Chimeric Antigen Receptor (CAR)-Modified T Cells Targeting CD19 in Children with Relapsed/Refractory ALL." Blood 126, no. 23 (2015): 683. http://dx.doi.org/10.1182/blood.v126.23.683.683.

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Background Targeted immunotherapy with T cells expressing a chimeric antigen receptor (CAR) can produce dramatic anti-tumor responses. We previously demonstrated complete remissions (CRs), prolonged persistence, and sustained responses in children and adults with relapsed/refractory (r/r) acute lymphoblastic leukemia (ALL) treated with CD19-specific CAR-modified T cells (CTL019). However, a subset (~25%) of patients has limited persistence of CTL019, which can increase the risk of relapse. We hypothesized that repeat infusion may prolong persistence in some patients but would be ineffective in

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Kurashova, Svetlana S., Maria S. Egorova, Anna N. Vetrova, et al. "The effect of carbohydrate adjuvants in the composition of the experimental hantavirus vaccine on the dynamics of neutralizing antibodies in the blood sera of guinea pigs." Journal of microbiology, epidemiology and immunobiology 101, no. 3 (2024): 383–92. http://dx.doi.org/10.36233/0372-9311-523.

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Introduction. Vaccination could be the most effective means of preventing hemorrhagic fever with renal syndrome (HFRS), which is one of the leading zoonoses and a major cause of natural disease in humans. Therefore, research to develop an effective vaccine and the search for new non-toxic and effective adjuvants that can enhance and prolong the immune response, reduce the antigen concentration and reduce the frequency of dose administration is an urgent task. The aim of the study was to determine the dependence of the immunogenic activity of an experimental hantavirus vaccine based on Puumala

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Chowdhury, Farah Diba, Mirza Omar Beg, Nusrath Jahan Chowdhury, Barsha Mojumder Papri, and Shukdeb Paul. "Association of Renal Functional Status in Different Stages of Diabetic Retinopathy." Medicine Today 37, no. 1 (2025): 114–18. https://doi.org/10.3329/medtoday.v37i1.79438.

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Introduction: Diabetic nephropathy (DN) and diabetic retinopathy (DR) are both complications of diabetic microangiopathy with similar pathogenesis and clinical relevance. Many studies have demonstrated an association between diabetic retinopathy and diabetic nephropathy in type 1 diabetes mellitus (T1DM) patients, but this association is less strong in T2DM. There is link exists between different stages of diabetic retinopathy and diabetic nephropathy in T2DM. Aims and Objective: To explore the renal functional status in different stages of diabetic retinopathy. Materials and Methods: This cro

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Dimopoulos, Meletios A., Constantinos Zervas, Athanassios Zomas, et al. "Treatment of Waldenström’s Macroglobulinemia With Rituximab." Journal of Clinical Oncology 20, no. 9 (2002): 2327–33. http://dx.doi.org/10.1200/jco.2002.09.039.

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PURPOSE: Waldenström’s macroglobulinemia (WM) is a low-grade lymphoplasmacytic lymphoma in which CD20 is usually expressed on tumor cells. There is evidence that patients with WM may benefit from treatment with the anti-CD20 monoclonal antibody rituximab. We performed a prospective phase II study to clearly define the activity of rituximab in patients with this disease. PATIENTS AND METHODS: Twenty-seven patients with WM were treated with rituximab 375 mg/m2 intravenously (IV) for 4 weeks. Three months after completion of rituximab, patients without evidence of progressive disease received rep

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Lim, Maksim, and Nurali Shavazi. "PREDICTORS OF THE DEVELOPMENT OF RECURRENT BRONCHIAL OBSTRUCTION IN CHILDREN." Международный журнал научной педиатрии 2, no. 11 (2023): 398–400. http://dx.doi.org/10.56121/2181-2926-2023-2-11-398-400.

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Abstract. Purpose of the study: to determine the significance of risk factors for the development of recurrent bronchial obstruction in children. Material and methods of research. A total of 240 children were examined and divided into 3 groups: Group I - patients with acute obstructive bronchitis (AOB), acute bronchiolitis (ABL), Group II - children with recurrent obstructive bronchitis (ROB) and bronchial asthma (BA), Group III - patients with acute bronchitis without bronchial obstruction (BA). To assess the significance of risk factors for the development of recurrent and relapsing course o

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Mehedie, Lt Col (Dr) Abdullah, Maj (Dr) Durdana Maheen, and Col Prof (Dr) Md Abdul Hamid. "Severity of Acute Appendicitis is Predicted by Hyperbilirubinemia: A Clinical Clue." Scholars Journal of Applied Medical Sciences 11, no. 10 (2023): 1796–800. http://dx.doi.org/10.36347/sjams.2023.v11i10.006.

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Background: One of the most frequent abdominal emergencies requiring emergency surgery is acute appendicitis, and appendectomy is the most common emergency procedure performed globally. There is an urgent need for a predictor of the severity of acute appendicitis since delayed identification and treatment of severe appendicitis are linked to higher risks of perforation and postoperative morbidity, mortality, and prolong hospital stay. Objectives: The aim of this study was to assess how the severity of acute appendicitis is predicted by hyperbilirubinemia. Methods: This descriptive cross-sectio

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Malav, Harshita, Divya Gehlot, and Shelly Chaudhary. "A RETROSPECTIVE STUDY ON FETOMATERNAL OUTCOME IN SECOND STAGE CESAREAN-SECTION." International Journal of Advanced Research 12, no. 02 (2024): 622–26. http://dx.doi.org/10.21474/ijar01/18337.

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Introduction:Second stage C-section are associated with poor fetomaternal outcome due to deeply engaged head ,less liquor,and thinned out LUS.This can lead to maternal morbidities like thinned out the lower uterine segment. This can lead to a high risk of maternal morbidities like an extension of the lower uterine segment incision, uterine atony, and injury to urinary bladder as well as neonatal morbidities such as birth asphyxia, NICU admission, and meconium aspiration syndrome. This study aims to observe the maternal and neonatal outcomes of cesarean delivery performed in the second stage of

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Zhang, Wei, Leqi Zhou, Guanyu Yu, et al. "Safety and efficacy of anti-CEA CAR-T cells to prolong relapse-free survival of colorectal cancer liver metastases patients after radical resection." Journal of Clinical Oncology 43, no. 16_suppl (2025): 3541. https://doi.org/10.1200/jco.2025.43.16_suppl.3541.

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3541 Background: Approximately 75% of colorectal cancer liver metastasis patients relapse within two years after surgery due to circulating tumor cells and microscopic residual disease. Specific chimeric antigen receptor (CAR) T-cell therapy, effective for hematological tumors, may also treat recurrent colorectal cancer liver metastases. Carcinoembryonic antigen (CEA) is a glycoprotein which is highly expressed in colorectal tumor. Therefore, this study aimed to evaluate the safety and efficacy of this therapy in postoperative colorectal cancer liver metastasis patients. Methods: We conducted

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Mohd Zulhilmi Aqil Muhamad and Noor Hafhizah Abd Rahim. "Expert System to Diagnose Dengue Fever." Universiti Malaysia Terengganu Journal of Undergraduate Research 1, no. 4 (2019): 67–76. http://dx.doi.org/10.46754/umtjur.v1i4.93.

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Expert system is a system that emulates experts to aid in decision making. This system can be applied in various categories such as diagnosis, prediction, interpretation, and others. Expert System to Diagnose Dengue Fever is a web-based system which is integrated with prolog language in order to provide rules for dengue fever detection. The aims of this research are to study dengue fever symptoms and other illnesses related to the fever, to design an inference engine, and to build an expert system. The challenges faced while developing this expert system were the complexity of prolog codes and

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