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1

Prolonged exposure. St. Martin's Press, 1998.

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2

Ann, Hembree Elizabeth, and Rothbaum Barbara Olasov, eds. Prolonged exposure therapy for PTSD: Emotional processing of traumatic experiences : therapist guide. Oxford University Press, 2007.

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3

Foa, Edna B. Prolonged exposure therapy for adolescents with PTSD: Emotional processing of traumatic experiences : therapist guide. Oxford University Press, 2008.

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4

McLeay, D. J. Responses of arctic graling (Thymallus arcticus) to acute and prolonged exposure to Yukon placer miner sediment. s.n, 1987.

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5

Beaumont, Matthew William. Exposure of seasonally acclimated brown trout, Salmo trutta, to copper in soft, acidic water: Sub-lethal effects upon oxygen consumption and prolonged swimming performance. University of Birmingham, 1995.

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6

Havill, Steven F. Prolonged Exposure. Worldwide, 2016.

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7

Havill, Steven F. Prolonged Exposure (Missing Mystery 36). Poisoned Pen Press, 2001.

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8

Foa, Edna, Elizabeth A. Hembree, Barbara Olasov Rothbaum, and Sheila Rauch. Prolonged Exposure Therapy for PTSD. Oxford University Press, 2019. http://dx.doi.org/10.1093/med-psych/9780190926939.001.0001.

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This therapist guide of prolonged exposure (PE) treatment is accompanied by the patient workbook, Reclaiming Your Life from a Traumatic Experience. The treatment and manuals are designed for use by a therapist who is familiar with cognitive behavioral therapy (CBT) and who has undergone an intensive training workshop for prolonged exposure by experts in this therapy. The therapist guide instructs therapists to implement this brief CBT program that targets individuals who are diagnosed with posttraumatic stress disorder (PTSD) or who manifest PTSD symptoms that cause distress and/or dysfunction
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9

Chrestman, Kelly R., Eva Gilboa-Schechtman, and Edna B. Foa. Prolonged Exposure Therapy for PTSD: Teen Workbook. Oxford University Press, 2008. http://dx.doi.org/10.1093/med:psych/9780195331738.001.0001.

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This online treatment program adapts the principles of Dr. Foa's proven effective Prolonged Exposure Therapy for adolescents suffering from Post-traumatic Stress Disorder (PTSD), and is based on the principles of prolonged exposure and emotional processing for use with those individuals who suffer from PTSD. The treatment is presented in modules that can be individually tailored to fit the needs of each patient. Because many adolescent PTSD sufferers do not initiate therapy on their own, but are referred to therapy by social workers, parents, or other authority figures, their willingness to pa
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10

Brown, Lily A., David Yusko, Hallie Tannahill, and Edna B. Foa. Prolonged Exposure Therapy for Post-Traumatic Stress Disorder. Edited by Charles B. Nemeroff and Charles R. Marmar. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190259440.003.0030.

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This chapter presents an overview of prolonged exposure therapy (PE), a highly efficacious and effective treatment for post-traumatic stress disorder (PTSD). First, emotional processing theory is reviewed, which provides the theoretical basis for PE and the key mechanisms underlying PTSD symptom reduction. Next, a synthesis of the robust evidence for the efficacy and effectiveness of PE is provided. The chapter reviews evidence that in addition to ameliorating PTSD symptoms, PE reduces secondary symptoms such as depression, suicidal ideation, anger, and substance use disorders. The chapter des
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11

Foa, Edna B., Kelly R. Chrestman, and Eva Gilboa-Schechtman. Prolonged Exposure Therapy for Adolescents with PTSD Therapist Guide. Oxford University Press, 2008. http://dx.doi.org/10.1093/med:psych/9780195331745.001.0001.

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Traumatic events, including sexual abuse, experiencing or witnessing violence, and natural disasters, are common among adolescents, and this online therapist guide presents a proven treatment for PTSD that has been adapted for the adolescent population. It applies the principles of Prolonged Exposure (PE) to help adolescents emotionally process their traumatic experiences and follows a four-phase treatment where the patients complete each module at their own rate of progress. It includes modules on motivational interviewing, case management, the rationale for treatment, information-gathering a
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12

Rothbaum, Barbara Olasov, Edna B. Foa, Sheila A. M. Rauch, and Erin R. Smith. Prolonged Exposure for PTSD in Intensive Outpatient Programs: Therapist Guide. Oxford University Press, Incorporated, 2020.

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13

Rauch, Sheila A. M., Barbara Olasov Rothbaum, Erin R. Smith, and Edna B. Foa. Prolonged Exposure for PTSD in Intensive Outpatient Programs (PE-IOP). Oxford University Press, 2020. http://dx.doi.org/10.1093/med-psych/9780190081928.001.0001.

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Trauma can leave a lasting impact on survivors. Some survivors are haunted by intrusive memories; avoid people, places, and situations related to the trauma; and feel constantly on edge due to posttraumatic stress disorder (PTSD) and related posttrauma reactions. Effective treatment can help survivors suffering with PTSD to process the trauma and no longer feel haunted by traumatic experiences from their past. Prolonged exposure (PE) therapy is a highly effective, flexible, individualized psychotherapy that reduces the symptoms of PTSD. PE is the most widely studied treatment for PTSD, with mo
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14

Back, Sudie E., Edna B. Foa, Therese K. Killeen, et al. Concurrent Treatment of PTSD and Substance Use Disorders Using Prolonged Exposure (COPE). Oxford University Press, 2015. http://dx.doi.org/10.1093/med:psych/9780199334513.001.0001.

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Concurrent Treatment of PTSD and Substance Use Disorders Using Prolonged Exposure (COPE) is a an integrated treatment cognitive-behavioral psychotherapy program designed for patients who have posttraumatic stress disorder (PTSD) and a co-occurring alcohol or drug use disorder. COPE represents an integration of two evidence-based treatments: Prolonged Exposure (PE) therapy for PTSD and Relapse Prevention for substance use disorders, where both the PTSD and substance use disorder are addressed concurrently in therapy by the same clinician, and patients can experience substantial reductions in bo
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15

Back, Sudie E., Edna B. Foa, Therese K. Killeen, et al. Concurrent Treatment of PTSD and Substance Use Disorders Using Prolonged Exposure (COPE). Oxford University Press, 2015. http://dx.doi.org/10.1093/med:psych/9780199334537.001.0001.

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Concurrent Treatment of PTSD and Substance Use Disorders Using Prolonged Exposure (COPE) is a an integrated treatment cognitive-behavioral psychotherapy program designed for patients who have posttraumatic stress disorder (PTSD) and a co-occurring alcohol or drug use disorder. COPE represents an integration of two evidence-based treatments: Prolonged Exposure (PE) therapy for PTSD and Relapse Prevention for substance use disorders, where both the PTSD and substance use disorder are addressed concurrently in therapy by the same clinician, and patients can experience substantial reductions in bo
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16

Concurrent Treatment of PTSD and Substance Use Disorders Using Prolonged Exposure (COPE). Oxford University Press, Incorporated, 2015.

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17

Rothbaum, Barbara Olasov, Edna Foa, Elizabeth A. Hembree, and Sheila Rauch. Prolonged Exposure Therapy for PTSD: Emotional Processing of Traumatic Experiences - Therapist Guide. Oxford University Press, Incorporated, 2019.

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18

Chrestman, Kelly R., Eva Gilboa-Schechtman, and Edna B. Foa. Prolonged Exposure Therapy for Adolescents with PTSD Therapist Guide (Treatments That Work). Oxford University Press, USA, 2008.

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19

Concurrent Treatment of Ptsd and Substance Use Disorders Using Prolonged Exposure (COPE). Oxford University Press, Incorporated, 2015.

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20

ICRP. ICRP Publication 82: Protection of the Public in Situations of Prolonged Radiation Exposure. Elsevier, 2000.

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21

Reclaiming Your Life from a Traumatic Experience: A Prolonged Exposure Treatment Program - Workbook. Oxford University Press, Incorporated, 2019.

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22

ICRP. ICRP Publication 82: Protection of the Public in Situations of Prolonged Radiation Exposure. Elsevier, 2000.

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23

Roy, Michael J., Albert Rizzo, JoAnn Difede, and Barbara O. Rothbaum. Virtual Reality Exposure Therapy for PTSD. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190205959.003.0013.

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Expert treatment guidelines and consensus statements identified imaginal exposure therapy as a first-line treatment for posttraumatic stress disorder (PTSD) more than a decade ago. Subsequently, an Institute of Medicine report concluded that cognitive–behavioral therapy with exposure therapy is the only therapy with sufficient evidence to recommend it for PTSD. Imaginal exposure has been the most widely used exposure approach. It requires patients to recall and narrate their traumatic experience repeatedly, in progressively greater detail, both to facilitate the therapeutic processing of relat
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24

The effect of prolonged exposure to 750⁰C air on the tribological performance of PM212. National Aeronautics and Space Administration, 1994.

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25

Rothbaum, Barbara, Edna Foa, and Elizabeth Hembree. Prolonged Exposure Therapy for PTSD: Emotional Processing of Traumatic Experiences Therapist Guide (Treatments That Work). Oxford University Press, USA, 2007.

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26

Rothbaum, Barbara, Edna Foa, and Elizabeth Hembree. Reclaiming Your Life from a Traumatic Experience: A Prolonged Exposure Treatment Program Workbook (Treatments That Work). Oxford University Press, USA, 2007.

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27

Belcher, Harolyn M. E., and Samantha Hutchison. Neurobiology of Intrauterine Opiate and Cocaine Exposure. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0182.

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Drug abuse results from a complex interplay among the drug, the individual and the socio-cultural environment. Current pain reliever, heroin, and OxyContin® use is reported in 0.9% (n = 19,000), 0.2% (n = 4,000), and 0.1% (n = 3,000), respectively, of pregnant women in the United States each year. Cocaine use was reported in 0.2% of pregnant women. Intrauterine drug exposure to opiates is associated with risk for narcotic abstinence syndrome, prenatal infections, and sudden infant death. Illicit drug use during pregnancy also places the mother-to-be at risk for reduced prenatal care, obstetric
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28

Rothbaum, Barbara Olasov, Edna B. Foa, Elizabeth A. Hembree, and Sheila A. M. Rauch. Reclaiming Your Life from a Traumatic Experience. Oxford University Press, 2019. http://dx.doi.org/10.1093/med-psych/9780190926892.001.0001.

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This workbook, written for patients, is part of a brief cognitive behavioral therapy (CBT) program for individuals who are diagnosed with posttraumatic stress disorder (PTSD) or who manifest PTSD symptoms that cause distress and/or dysfunction following various types of trauma. The overall aim of the treatment is to help trauma survivors emotionally process their traumatic experiences to diminish or eliminate PTSD and other trauma-related symptoms. The term “prolonged exposure” (PE) reflects the fact that the treatment program emerged from the long tradition of exposure therapy for anxiety dis
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29

Markowitz, John C. Interpersonal Psychotherapy for Posttraumatic Stress Disorder. Oxford University Press, 2016. http://dx.doi.org/10.1093/med:psych/9780190465599.001.0001.

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Posttraumatic stress disorder (PTSD) is a prevalent, debilitating public health problem. It is a treatable condition, but the predominant approach to treatment has involved exposing patients to their worst fears, the reminders of their traumas. Many patients and therapists find this process unpleasant, and exposure-based treatment does not help everyone. We recently studied Interpersonal Psychotherapy (IPT), a non-exposure treatment that focuses on restoring the numbed emotions of patients with PTSD and helping patients use them to reconstruct a sense of safety in their environment. IPT focuse
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30

Banjara, Manoj, and Damir Janigro. Effects of the Ketogenic Diet on the Blood-Brain Barrier. Edited by Detlev Boison. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190497996.003.0030.

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Ketone bodies (KBs) are always present in the blood, and their levels increase after high-fat diet intake, prolonged exercise, or extended fasting. Thus, one can predict effects on the brain capillary endothelium from high levels of ketones in the blood. Prolonged exposure of blood-brain barrier (BBB) endothelial cells to KBs induces expression of monocarboxylate transporters and enhances brain uptake of KBs. In addition, cell migration and expression of gap junction proteins are up-regulated by KBs. Thus, beneficial effects of the ketogenic diet may depend on increased brain uptake of KBs to
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31

Rothbaum, Barbara Olasov, Edna B. Foa, and Elizabeth A. Hembree. Reclaiming Your Life from a Traumatic Experience: Workbook. Oxford University Press, 2007. http://dx.doi.org/10.1093/med:psych/9780195308488.001.0001.

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Best used in combination with treatment with a mental health professional, this online workbook will help patients work through PTSD regardless of the type of trauma experienced. This program will reduce anxiety and distress as patients learn to face memories of trauma, while processing emotions about the event using a scientifically tested and proven technique called Prolonged Exposure Therapy (PE). It provides a guide for patients to learn how to confront these situations and begin to re-evaluate feelings and beliefs in order to think differently about the experience. It covers how to partic
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32

Hainline, Brian, Lindsey J. Gurin, and Daniel M. Torres. Concussion. Oxford University Press, 2019. http://dx.doi.org/10.1093/med/9780190937447.001.0001.

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Concussion is a type of mild traumatic brain injury, is common, and occurs both in sport and as a result of falls or accidents. Concussion has become an increasingly recognized public health concern, largely driven by prominent media coverage of athletes who have sustained concussion. Although much has been written about this condition, its natural history is still not well understood, and practitioners are only now beginning to recognize that concussion often manifests in different clinical domains. These may require targeted treatment in and of themselves; otherwise, persistent post-concussi
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33

Tol, Wietse A., Mark J. D. Jordans, Dessy Susanty, and Joop T. V. M. de Jong. Trials for people with mental disorders and conditions associated with stress. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199680467.003.0013.

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Exposure to negative life events is associated with worse mental health outcomes. The chapter provides an overview of mental disorders and conditions specifically associated with stress. It discusses proposals for a new category of conditions and disorders specifically associated with stress (e.g. symptoms of acute stress, post-traumatic stress disorder (PTSD), complex PTSD, prolonged grief disorder, adjustment disorder) and summarizes recent guidance for interventions. A preventive school-based intervention with children affected by armed conflict and cluster randomized trial in Indonesia is
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34

Rauch, Sheila A. M., and Israel Liberzon. Mechanisms of Action in Psychotherapy. Edited by Israel Liberzon and Kerry J. Ressler. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190215422.003.0019.

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Therapy at its core is based on learning, and learning at its core is biological. Experience that is not in some way encoded in the brain and/or body is lost. This chapter provides a discussion of mechanisms of therapy research in PTSD in which the goal is to understand how PTSD therapy works. First, the chapter reviews what a mechanism is and how therapeutic mechanisms are examined. It then discusses the importance of therapeutic mechanisms research within the broader realm of mental health research. It focuses on prolonged exposure (PE) therapy for PTSD as an example of application of mechan
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35

Nielsen-Saines, Karin. Antiretroviral Therapy in Children and Newborns. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190493097.003.0027.

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HIV-infected infants and children have a different, more progressive disease course compared to that of adults given that early infection leads to sustained, high-magnitude viremia with significant seeding of reservoirs in the first months of life. Early diagnosis of HIV infection is pivotal in the management of infants and prevention of HIV-associated morbidity and mortality. The availability of potent pediatric antiretroviral formulations encompassing different classes of drugs for infected infants and young children is limited. Significant advancements have been achieved in the area of infa
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36

Ware, Lorraine B. Pathophysiology of acute respiratory distress syndrome. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0108.

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The acute respiratory distress syndrome (ARDS) is a syndrome of acute respiratory failure characterized by the acute onset of non-cardiogenic pulmonary oedema due to increased lung endothelial and alveolar epithelial permeability. Common predisposing clinical conditions include sepsis, pneumonia, severe traumatic injury, and aspiration of gastric contents. Environmental factors, such as alcohol abuse and cigarette smoke exposure may increase the risk of developing ARDS in those at risk. Pathologically, ARDS is characterized by diffuse alveolar damage with neutrophilic alveolitis, haemorrhage,
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37

Nadel, Ira. Philip Roth. Oxford University Press, 2021. http://dx.doi.org/10.1093/oso/9780199846108.001.0001.

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This account of Philip Roth traces the psychological and artistic origins of his creative life. It examines the major events of his career, while identifying a series of personal themes in his writing, from his relationship with Judaism to family, marriage, Eastern Europe, and America. It addresses his private challenges, from romance and health to surviving as a writer burdened with success. The book also reflects how living outside the United States, initially in Italy and then England, plus his visits to Eastern Europe and exposure to their oppressed writers, affected his writing. In partic
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38

Aksamit, Timothy R. Diffuse Lung Disease. Oxford University Press, 2012. http://dx.doi.org/10.1093/med/9780199755691.003.0617.

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Diffuse lung disease includes a wide range of parenchymal lung diseases that have infectious, inflammatory, malignant, drug, occupational or environmental, and other causes. Although many identifiable causes are recognized, the cause of most cases of diffuse lung disease in many published series is idiopathic. The clinical course may be acute or prolonged and may progress rapidly to life-threatening respiratory failure with death, or it may be indolent over many years. In most instances, a differential diagnosis can readily be formulated by obtaining the medical history, with emphasis on the n
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