Academic literature on the topic 'Promonocytic lymphoma cells'

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Journal articles on the topic "Promonocytic lymphoma cells"

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Mikkelsen, Kathleen, Monica D. Prakash, Nyanbol Kuol, Kulmira Nurgali, Lily Stojanovska, and Vasso Apostolopoulos. "Anti-Tumor Effects of Vitamin B2, B6 and B9 in Promonocytic Lymphoma Cells." International Journal of Molecular Sciences 20, no. 15 (2019): 3763. http://dx.doi.org/10.3390/ijms20153763.

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Chronic inflammation can lead to tumour initiation and progression. Vitamin B complex has the ability to regulate the immune response and, therefore, inflammation but many of the mechanistic and molecular processes involved in this regulation are still not fully understood. This study sought to determine some of these processes by studying the effects of vitamin B2 (riboflavin) B6 (pyridoxine) and B9 (folic acid) on un-differentiated pro-monocytic lymphoma cells in regard to their ability to alter the proliferation, migration, apoptosis, cytokines and expression levels of programmed death liga
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Li, Xing, Hua-Fang Lin, Arnel Agustin, et al. "The Value of Sysmex White Precursor Cell Channel in Distinguishing Circulating Large Blastoid Lymphoma Cells from Blasts." American Journal of Clinical Pathology 162, Supplement_1 (2024): S173—S174. http://dx.doi.org/10.1093/ajcp/aqae129.382.

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Abstract Background There are rare cases of lymphoma presenting with circulating large blastoid cells mimicking blasts. These abnormal cells usually are medium to large in size with high nucleus-to-cytoplasmic ratio, fine to slightly condensed chromatin, prominent nucleoli, and scant to moderate amount of cytoplasm. Distinguishing them from real blasts is challenging, and although flow cytometry provides a definitive answer, pathologists may feel compelled to offer a quick preliminary assessment to the clinical team, particularly during weekends when flow cytometry is not accessible. We have r
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Pontvert-Delucq, S., J. Breton-Gorius, C. Schmitt, et al. "Characterization and functional analysis of adult human bone marrow cell subsets in relation to B-lymphoid development." Blood 82, no. 2 (1993): 417–29. http://dx.doi.org/10.1182/blood.v82.2.417.417.

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Abstract To study the frontiers between pluripotent stem cells and committed progenitors and to further define the B-cell pathway in adult bone marrow (BM), CD34+ subpopulations and CD34- B-lineage cells were analyzed by multiparameter flow cytometry, studied by light and electron microscopy, and in short-term and long-term cultures (LTC). While the total CD34+ cells represent 4.9% +/- 0.8 of BM mononuclear cells within the lymphoid-blast window, 73.8 +/- 3.5%, 14.4 +/- 1.8% and 8.8 +/- 2.9% of them were CD34+ CD10- CD19-, CD34+ CD10+ CD19+, and CD34+ CD10+ CD19-, respectively. CD34+ CD10+ CD1
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Pontvert-Delucq, S., J. Breton-Gorius, C. Schmitt, et al. "Characterization and functional analysis of adult human bone marrow cell subsets in relation to B-lymphoid development." Blood 82, no. 2 (1993): 417–29. http://dx.doi.org/10.1182/blood.v82.2.417.bloodjournal822417.

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To study the frontiers between pluripotent stem cells and committed progenitors and to further define the B-cell pathway in adult bone marrow (BM), CD34+ subpopulations and CD34- B-lineage cells were analyzed by multiparameter flow cytometry, studied by light and electron microscopy, and in short-term and long-term cultures (LTC). While the total CD34+ cells represent 4.9% +/- 0.8 of BM mononuclear cells within the lymphoid-blast window, 73.8 +/- 3.5%, 14.4 +/- 1.8% and 8.8 +/- 2.9% of them were CD34+ CD10- CD19-, CD34+ CD10+ CD19+, and CD34+ CD10+ CD19-, respectively. CD34+ CD10+ CD19+ cells
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Maio, M., G. Tessitori, A. Pinto, M. Temponi, A. Colombatti, and S. Ferrone. "Differential role of distinct determinants of intercellular adhesion molecule-1 in immunologic phenomena." Journal of Immunology 143, no. 1 (1989): 181–88. http://dx.doi.org/10.4049/jimmunol.143.1.181.

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Abstract This study analyzed 1) the relationship between the molecules recognized by anti-intercellular adhesion molecule-1 (ICAM-1) mAb RR 1/1 and by anti-96K melanoma-associated Ag mAb CL203.4 in lymphoid cells, 2) the induction of ICAM-1 on activated PBMC, and 3) the functional activity of distinct and spatially distant determinants recognized by mAb CL203.4 and RR1/1. Sequential immunoprecipitation experiments showed that the determinant recognized by mAb CL203.4 is expressed on a slightly broader population of ICAM-1 molecules than that defined by mAb RR1/1. Serologic and immunochemical a
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Guskova, N. K., O. N. Selyutina, I. B. Lysenko, et al. "Diagnosis of acute myelomonocytic leukemia in a patient with extramedullary testicular lesion." Oncohematology 17, no. 4 (2022): 81–87. http://dx.doi.org/10.17650/1818-8346-2022-17-4-81-87.

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A complex clinical case of acute myelomonocytic leukemia with extramedullary lesion of the testis is presented. patient yu., born in 1968, applied to the National Medical Research Centre for Oncology (Rostov-on-don) after an injury to the inguinal region. ultrasound was performed: in the right testicle in the middle third, a mass of 30 × 23 × 16 mm was revealed. A biopsy was performed: the morphological picture is characteristic of a typical seminoma. Orchofuniculectomy was performed on the right. Histopathological conclusion: the morphological picture is more characteristic of a typical semin
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Faltynek, C. R., L. R. Finch, P. Miller, and W. R. Overton. "Treatment with recombinant IFN-gamma decreases cell surface CD4 levels on peripheral blood monocytes and on myelomonocyte cell lines." Journal of Immunology 142, no. 2 (1989): 500–508. http://dx.doi.org/10.4049/jimmunol.142.2.500.

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Abstract The human cell surface protein CD4 is not only an important accessory molecule in the activation of MHC class-II-restricted T cells, but has also been implicated to be a receptor for the human immunodeficiency virus HIV-I on lymphoid and monocytic cells. We have found that a 24-h treatment of the promonocytic leukemia cell line U937 with rIFN-gamma decreases the expression of the CD4 Ag by 50% as measured by cytofluorographic analysis. The decrease in CD4 expression was dependent on the concentration of rIFN-gamma, with maximal effects occurring at 20 to 200 U/ml. The decrease appeare
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Golban, Rodica, Natalia Lisita, Luminita Dediu, and Marin Crangaci. "Acute myelomonoblastic leukemia in children, the particularities of extramedullary infiltration based on a clinical case." Bulletin of the Academy of Sciences of Moldova. Medical Sciences 76, no. 2 (2023): 83–86. http://dx.doi.org/10.52692/1857-0011.2023.2-76.15.

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Childhood acute myeloidleukemia (AML) represents approximately 5% of childhood malignancies and 15% to 25% of pediatric acute leukemia. The extramedullary manifestation of infiltrating clonal blast populations in a variety of organs and tissues in acute myeloid leukemia (AML) is defined as a distinct entity in the 2016 WHO classification of myeloid neoplasms, myeloid sarcoma The rate of complete remission after induction chemotherapy was lower in patients with extramedullary infiltration, overall survival and event-free survival were not different between patients with and without extramedulla
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Zheng, Xuesen, Amandine Tan, Maria del Pilar Casares Alaez, et al. "An Integrated Single Cell Immunogenomic Atlas Reveals Pathways of Clonal Expansion, Inflammation and Dyserythropoiesis in Low and High-Risk Clonal Haematopoiesis." Blood 142, Supplement 1 (2023): 812. http://dx.doi.org/10.1182/blood-2023-174947.

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Clonal haematopoiesis (CH) describes age-related clonal expansion of mutant haematopoietic cells in the absence of overt haematological disease. Growing evidence suggests that individuals with ‘high risk’ (HR-CH) have increased risk of blood cancer, auto-inflammatory and cerebro-cardiovascular disease. We aimed to better understand genomic and immunological events associated with progression of CH. By setting up a cohort of individuals undergoing hip arthroplasty ( n=432, 58% female, age range 50-90, mean 69 years), we detected CH mutations (sensitivity to 0.2% variant allele frequency, VAF) i
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Kaur, Jaspreet, Gabriella Diamantino, Katherine Morrison, et al. "Acute myeloid leukemia with peripheral lymph node involvement in dogs: A retrospective study of 23 cases." Veterinary Pathology, November 14, 2024. http://dx.doi.org/10.1177/03009858241295397.

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Acute myeloid leukemia (AML) can infiltrate extramedullary tissues, such as the liver, spleen, and lymph nodes and can be difficult to differentiate from lymphoma in cytologic and histologic specimens. Our goal was to identify cytologic features that would support a diagnosis of AML in peripheral lymph node aspirates, for which we used the term extramedullary AML (eAML). Medical records of 23 dogs with a diagnosis of AML and archived lymph node aspirate smears from 2016 to 2024 were reviewed across 4 institutions. Inclusion criteria included ≥50% myeloid blasts plus differentiating myeloid cel
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Dissertations / Theses on the topic "Promonocytic lymphoma cells"

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Mikkelsen, Kathleen. "The Effects of Vitamin B6 and B12 on Inflammation and Cancer." Thesis, 2022. https://vuir.vu.edu.au/43344/.

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We are only just beginning to understand the intricate relationship between nutrition, immune health, inflammation, and cancer. Epidemiological studies have demonstrated a clear association between inflammation and cancer development. Both undernutrition and overnutrition (malnutrition) have been shown to have a significant impact on immune health and function. Even in countries where food is plentiful, a diet high in processed food can be high in calories whilst being nutritionally deficient. The emergence of B vitamins as anti-inflammatory and anti-cancer agents is an area which in recent ye
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Book chapters on the topic "Promonocytic lymphoma cells"

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Ross, J. A., and M. J. Auger. "The biology of the macrophage." In The Macrophage Second edition. Oxford University PressNew York, NY, 2002. http://dx.doi.org/10.1093/oso/9780192631978.003.0001.

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Abstract The macrophage is the major differentiated cell of the mononuclear phagocyte system. This system comprises bone marrow monoblasts and promonocytes, peripheral blood monocytes and tissue macrophages. Macrophages are widely distributed throughout the body, displaying great structural and functional heterogeneity. They are to be found in lymphoid organs, the liver, lungs, gastrointestinal tract, central nervous system (CNS), serous cavities, bone, synovium and skin, and participate in a wide range of physiological and pathological processes.
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