Academic literature on the topic 'Promoter opening'

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Journal articles on the topic "Promoter opening"

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Murakami, Kenji, Pierre-Jean Mattei, Ralph E. Davis, Huiyan Jin, Craig D. Kaplan, and Roger D. Kornberg. "Uncoupling Promoter Opening from Start-Site Scanning." Molecular Cell 59, no. 1 (2015): 133–38. http://dx.doi.org/10.1016/j.molcel.2015.05.021.

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BURNS, Helen D., Tamara A. BELYAEVA, Stephen J. W. BUSBY, and Stephen D. MINCHIN. "Temperature-dependence of open-complex formation at two Escherichia coli promoters with extended −10 sequences." Biochemical Journal 317, no. 1 (1996): 305–11. http://dx.doi.org/10.1042/bj3170305.

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We have studied the formation of open complexes between purified RNA polymerase from Escherichia coli and DNA fragments carrying the galP1 promoter, a promoter with an extended -10 region. Unusually, these complexes are formed readily at low temperatures. This low-temperature opening is unaffected by deletions of either upstream or downstream promoter sequences. We conclude that low-temperature open-complex formation is due to specific base sequences in and just upstream of the extended -10 region. In contrast, open complexes are not formed at low temperatures with DNA fragments carrying the E
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Sandoz, Jérémy, and Frédéric Coin. "Unified promoter opening steps in eukaryotic gene expression." Oncotarget 8, no. 49 (2017): 84614–15. http://dx.doi.org/10.18632/oncotarget.21387.

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Kim, Hajin, Guo-Qing Tang, Smita S. Patel, and Taekjip Ha. "Promoter Opening-Closing Dynamics of Mitochondrial RNA Polymerase." Biophysical Journal 100, no. 3 (2011): 65a. http://dx.doi.org/10.1016/j.bpj.2010.12.555.

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Nelson, Everette J. R., Laura M. Tuschong, and Dennis D. Hickstein. "Lentiviral Vectors Incorporating Ubiquitous Chromatin Opening Element Driving Canine CD18 Expression." Blood 128, no. 22 (2016): 5890. http://dx.doi.org/10.1182/blood.v128.22.5890.5890.

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Abstract Leukocyte adhesion deficiency type 1 (LAD1) in humans is caused due to mutations in the ITGB2 gene encoding the leukocyte CD18 subunit (b2 integrin). This results in defective leukocyte adhesion and migration leading to recurrent episodes of life-threatening bacterial infection. Canine leukocyte adhesion deficiency (CLAD) represents a disease-specific large animal model of LAD1 in which new therapeutic approaches could be tested. Our previous studies have demonstrated variable efficiency of CD18 expression under the control of several promoters. These include cellular promoters such a
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Micorescu, Michael, Sebastian Grünberg, Andreas Franke, Patrick Cramer, Michael Thomm, and Michael Bartlett. "Archaeal Transcription: Function of an Alternative Transcription Factor B from Pyrococcus furiosus." Journal of Bacteriology 190, no. 1 (2007): 157–67. http://dx.doi.org/10.1128/jb.01498-07.

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ABSTRACT The genome of the hyperthermophile archaeon Pyrococcus furiosus encodes two transcription factor B (TFB) paralogs, one of which (TFB1) was previously characterized in transcription initiation. The second TFB (TFB2) is unusual in that it lacks recognizable homology to the archaeal TFB/eukaryotic TFIIB B-finger motif. TFB2 functions poorly in promoter-dependent transcription initiation, but photochemical cross-linking experiments indicated that the orientation and occupancy of transcription complexes formed with TFB2 at the strong gdh promoter are similar to the orientation and occupanc
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Barinova, N., E. Zhilina, I. Bass, V. Nikiforov та A. Kulbachinskiy. "Lineage-Specific Amino Acid Substitutions in Region 2 of the RNA Polymerase σ Subunit Affect the Temperature of Promoter Opening". Journal of Bacteriology 190, № 8 (2008): 3088–92. http://dx.doi.org/10.1128/jb.00008-08.

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ABSTRACT Highly conserved amino acid residues in region 2 of the RNA polymerase σ subunit are known to participate in promoter recognition and opening. We demonstrated that nonconserved residues in this region collectively determine lineage-specific differences in the temperature of promoter opening.
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Guo, Y., and J. D. Gralla. "Promoter opening via a DNA fork junction binding activity." Proceedings of the National Academy of Sciences 95, no. 20 (1998): 11655–60. http://dx.doi.org/10.1073/pnas.95.20.11655.

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He, Yuan, Chunli Yan, Jie Fang, et al. "Near-atomic resolution visualization of human transcription promoter opening." Acta Crystallographica Section A Foundations and Advances 73, a1 (2017): a256. http://dx.doi.org/10.1107/s0108767317097483.

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He, Yuan, Chunli Yan, Jie Fang, et al. "Near-atomic resolution visualization of human transcription promoter opening." Nature 533, no. 7603 (2016): 359–65. http://dx.doi.org/10.1038/nature17970.

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Dissertations / Theses on the topic "Promoter opening"

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Plaskon, Randolph Richard. "DNA curvature and fluctuational base pair opening in the promoter regions of escherichia coli." Diss., Georgia Institute of Technology, 1988. http://hdl.handle.net/1853/25323.

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Hantsche, Merle Aminata [Verfasser], and Patrick [Akademischer Betreuer] Cramer. "Structure of the closed Pol II transcription initiation complex and implications for promoter opening / Merle A. Hantsche ; Betreuer: Patrick Cramer." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2016. http://d-nb.info/1122435711/34.

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Sandoz, Jérémy. "Rôles de TFIIH dans l’ouverture du promoteur et le remodelage de la chromatine lors la transcription des gènes de classe II." Thesis, Strasbourg, 2019. http://www.theses.fr/2019STRAJ027/document.

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La synthèse des ARN messagers est un processus hautement régulé. Pendant l’initiation de la transcription, un nombre important de protéines est recruté au niveau du promoteur des gènes, comprenant l’ARN polymérase II, les facteurs généraux de transcription comme TFIIH, des co-activateurs et des remodeleurs de la chromatine. L’assemblage du complexe de pré-initiation sur les promoteurs est suivi par leur ouverture. Les modèles acceptés à ce jour suggéraient que la transcription des gènes de classe II nécessite les activités ATPase et hélicase de la sous-unité XPB de TFIIH afin d’ouvrir le promo
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Dienemann, Christian [Verfasser], Patrick [Akademischer Betreuer] Cramer, Patrick [Gutachter] Cramer, and Ralf [Gutachter] Ficner. "Structural and Functional Investigation of Promoter Distortion and Opening in the RNA Polymerase II Cleft / Christian Dienemann ; Gutachter: Patrick Cramer, Ralf Ficner ; Betreuer: Patrick Cramer." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2019. http://d-nb.info/1178115704/34.

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Longlade, Jérémy. "Synthèse de nouveaux additifs pour peinture : applications aux peintures polyurethane et epoxy et impact sur les propriétés des films." Thesis, Mulhouse, 2015. http://www.theses.fr/2015MULH8634.

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Cette thèse en partenariat industriel s’intéresse aux peintures polyuréthane et époxy utilisées à des fins protectrices pour des applications ferroviaires. L’objectif de ce projet est de développer de nouveaux additifs spécifiques à ces peintures afin d’améliorer les propriétés mécaniques et adhésives des films sur acier, tout en gardant une bonne dispersion des charges minérales présentes dans la formulation. Des additifs polymères ont été développés. Ces polymères miscibles avec la résine ont été synthétisés par polymérisation cationique (technique du monomère activé) ou anionique coordinée,
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Dienemann, Christian. "Structural and Functional Investigation of Promoter Distortion and Opening in the RNA Polymerase II Cleft." Doctoral thesis, 2018. http://hdl.handle.net/11858/00-1735-0000-002E-E587-B.

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程淑媚. "Ultrasound Promoted Ring-opening of α,β-Unsaturated Dioxolanes with Grignard Reagents". Thesis, 1997. http://ndltd.ncl.edu.tw/handle/03302136913758632238.

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Shiau, Chung-Wai, and 蕭崇瑋. "1. Tungsten hexacarbonyl promoted desulfurpolymerization reaction 2.Ring opening metathesis of norbornene derivatives, design and synthesis of nonlinear optical polymers." Thesis, 1998. http://ndltd.ncl.edu.tw/handle/53924294530625094608.

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碩士<br>國立臺灣大學<br>化學系<br>86<br>We have recently reported a novel W(CO)6-mediated desulfurdimerization reaction of dithioacetals leading to the carbon-carbon double bond formation. Different bisthioacetals with substituted aromatic rings were designed which on treatment with W(CO)6 underwent desulfurpolymerization to obtain substituted poly(para-phenylenevinylenes). Group 6 metal carbonyls are thiophilic reagents to promote homolytic cleavage of carbon sulfur bonds. The resulting sulfur-containing metallic i
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Books on the topic "Promoter opening"

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Kien, Jenny. Prevention in mental health: Presentations at the opening conference of the program to promote prevention in the field of mental health. Paul Baerwald School of Social Work, The Hebrew University of Jerusalem, 1999.

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Dressler, John. Granville Bantock (1868-1946). Liverpool University Press, 2020. http://dx.doi.org/10.3828/liverpool/9781942954798.001.0001.

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This volume is the first published study to bring together a variety of materials which represent the life and works of Sir Granville Bantock (1868-1946), British composer, arranger, editor, music department administrator, competitive singing promoter and adjudicator, world traveler, lover of life, literature and philosophy, radio talk presenter, champion of works of other rising British composers over his own, husband and father. His works alone total over 600, yet many remain in manuscript housed for access at the Cadbury Special Collections Library on the campus of the University of Birming
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Fernandes, Sujatha. Rumbas in the Barrio. Oxford University Press, 2017. http://dx.doi.org/10.1093/acprof:oso/9780190618049.003.0006.

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This chapter presents an alternative example of the state-sponsored storytelling workshops conducted through the Misión Cultura program in Venezuela under the former radical leftist leader Hugo Chávez. The Misión Cultura provides an opportunity to examine what kinds of storytelling might be available in a context of heightened social movements and a state that has been rolling back neoliberalism. While the Misión Cultura promotes forms of subject-making and narrative based in dominant liberal tropes, it has also created openings for the telling of stories grounded in collective movements and s
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Nadler, Anthony, and A. J. Bauer, eds. News on the Right. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780190913540.001.0001.

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This volume seeks to initiate a new interdisciplinary field of scholarly research focused on the study of right-wing media and conservative news. To date, the study of conservative or right-wing media has proceeded unevenly, cross-cutting several traditional disciplines and subfields, with little continuity or citational overlap. This book posits a new multifaceted object of analysis—conservative news cultures—designed to promote concerted interdisciplinary investigation into the consistent practices or patterns of meaning making that emerge between and among the sites of production, circulati
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McDaniel, Justin Thomas. Buddhist Museums and Curio Cabinets. University of Hawai'i Press, 2017. http://dx.doi.org/10.21313/hawaii/9780824865986.003.0004.

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This chapter looks at the rise of Buddhist museums in contemporary Asia. Curators at private and sometimes explicitly sectarian Buddhist museums have attempted to appeal to a wider audience and have abandoned particular sect’s rituals, liturgies, symbols, and teachings to promote a new vision of Buddhism without borders. This opening up of their collections, as well as the active acquisition of new material, demonstrates a particular type of Buddhist ecumenism – an ecumenism without an agenda. The multiple affective encounters these museums allow create ecumenical environments allow visitors t
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Newton, Hannah. ‘She Sleeps Well and Eats an Egg’. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198779025.003.0003.

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Serious illness often left the body weak and lean, full of the ‘footsteps of disease’; it wasn’t until full strength and flesh had returned that the patient was pronounced back to health. This chapter explores the second stage of recovery in contemporary perceptions, the restoration of strength, or ‘convalescence’. It asks how the patient’s growing strength was measured and promoted, and unveils a concept of convalescent care, ‘analeptics’. The central argument is that both the mechanisms and the measures for the restoration of strength were intimately connected to the ‘non-natural things’, si
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Gold, Roberta. “The Right to Lease and Occupy a Home”. University of Illinois Press, 2017. http://dx.doi.org/10.5406/illinois/9780252038181.003.0003.

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This chapter examines how tenants addressed three public policy questions: public housing, slum clearance, and civil rights. The rent-control statutes that tenants vigorously defended served to moderate prices that would otherwise be set higher by the law of supply and demand. However, many tenants and housers were aware that rent control was a superficial fix. The underlying problem was scarcity of housing and a consequent landlord's market. Therefore from the Depression onward, the city's tenants and their allies also promoted programs to build new rental units and improve old ones. The chap
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Gunn, Sarah. Stone House Construction. CSIRO Publishing, 2012. http://dx.doi.org/10.1071/9780643106857.

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Stone House Construction is a comprehensive study of Australian stone building techniques in a residential context, for people with an interest in building or renovating, including property owners, architects and builders. It has a strong theme of historic stone buildings, as traditional forms of building respond to the need for structural integrity and stability over time against weathering.&#x0D; The book covers aspects of building in locally sourced stone, from quarrying on-site to building arches over openings for upper storey walls, and is a source book of examples and methods to help the
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Marlow, Eugene. Jazz in China. University Press of Mississippi, 2018. http://dx.doi.org/10.14325/mississippi/9781496817990.001.0001.

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This book traces China's introduction to jazz in the early 1920s, its interruption by Chinese leadership under Mao in 1949, and its rejuvenation in the early 1980s with the start of China's opening to the world under Premier Deng Xiaoping. Covering a span of almost one hundred years, the book focuses on a variety of subjects—the musicians who initiated jazz performances in China, the means by which jazz was incorporated into Chinese culture, and the musicians and venues that now present jazz performances. Featuring unique, face-to-face interviews with leading indigenous jazz musicians in Beiji
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Morrell, Kit. Pompey, Cato, and the Governance of the Roman Empire. Oxford University Press, 2017. http://dx.doi.org/10.1093/acprof:oso/9780198755142.001.0001.

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This book examines attempts to improve provincial governance from 70–50, particularly the contributions of Gnaeus Pompeius Magnus and the younger Marcus Porcius Cato. It contends that Romans of the late republic were more concerned about the problems of their empire than is generally recognized, and were taking steps to address them. These efforts ranged well beyond the sanctions of the extortion law to encompass show trials, exemplary governance, and ideas drawn from moral philosophy, culminating in 52–50 in a reform programme which combined what Cicero called ‘Cato’s policy’ of ethical gover
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Book chapters on the topic "Promoter opening"

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Sclavi, Bianca. "Chapter 2. Opening the DNA at the Promoter; The Energetic Challenge." In RNA Polymerases as Molecular Motors. Royal Society of Chemistry, 2009. http://dx.doi.org/10.1039/9781847559982-00038.

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Martin-Vaca, Blanca, and Didier Bourissou. "Chapter 2. Ring-opening Polymerization Promoted by Brønsted Acid Catalysts." In Polymer Chemistry Series. Royal Society of Chemistry, 2018. http://dx.doi.org/10.1039/9781788015738-00037.

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Yagci, Yusuf, and Mustafa Degirmenci. "Photoinduced Free Radical Promoted Cationic Block Copolymerization by Using Macrophotoinitiators Prepared by ATRP and Ring-Opening Polymerization Methods." In ACS Symposium Series. American Chemical Society, 2003. http://dx.doi.org/10.1021/bk-2003-0854.ch027.

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Birch, Kean. "Neoliberal Bioeconomies? Co-constructing Markets and Natures." In Bioeconomy and Global Inequalities. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-68944-5_3.

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AbstractThe bioeconomy is a key low-carbon transition pathway to address climate change promoted by a range of policymakers. The bioeconomy has been defined as a market-based strategy for dealing with environmental problems, largely because it seeks to insert bio-based products, fuels, and materials into prevailing economic infrastructures and institutions, rather than challenging underlying capitalist logics. As such, it can be seen as a ‘neoliberal’ response to climate change that reflects theoretical debates about the neoliberalization of nature. Such criticism, however, tends to treat markets as aberrations of nature and disrupting notions of a pristine, untouched natural state. In contrast, I argue that analysing the bioeconomy reveals the co-construction of markets and natures, rather than the imposition of markets on natures. Opening up criticism helps to provide an understanding of how else the bioeconomy could be organized and of the sorts of socio-material arrangements that we view as supportable.
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Hess, Daniel Baldwin, and Alex Bitterman. "Who Are the People in Your Gayborhood? Understanding Population Change and Cultural Shifts in LGBTQ+ Neighborhoods." In The Life and Afterlife of Gay Neighborhoods. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-66073-4_1.

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AbstractGay neighborhoods, like all neighborhoods, are in a state of continual change. The relevance of gay neighborhoods—originally formed to promote segregation of individuals who identify as sexual minorities—is lately challenged by advances in technology, experiences with pandemics, shifts in generational opinion and social values, increasing acceptance of LGBTQ+ individuals, and (in certain places) increased rights and protections for LGBTQ+ individuals. This confluence of change has created for many people anxiety related to the belief that gay neighborhoods may be dissolving or even disappearing altogether. Seeking to address these concerns, this opening chapter of the book The Life and Afterlife of Gay Neighborhoods: Renaissance and Resurgence presents eight important takeaway messages distilled from the chapters in this volume that, taken together, provide an in-depth overview of the formation, maturation, current challenges, and future prospects of LGBTQ+ spaces in urban environments. Findings suggest that shifts in patterns of residence, socialization, and entertainment for LGBTQ+ residents and visitors across metropolitan space have resulted in certain gay neighborhoods becoming less gay while other neighborhoods become more gay. In this time of social change, economic inequities, public health crises, and technological evolution, gay neighborhoods provide a culturally and historically significant template for communities in confronting adversity, fear, and discrimination. At this point in their maturity, gay neighborhoods have reached a plateau in their evolution; from here we pause to consider the current state of gay neighborhoods—and trajectories that might describe their future form—as we contemplate the importance of gay neighborhoods in the ongoing advancement of LGBTQ+ people everywhere. We conclude by observing that while gayborhoods have experienced a certain level of de-gaying, the trend toward viewing gayborhoods as inclusive and gay-friendly places de-emphasizes the self-segregation aspects of gayborhoods that were important to their initial formation; consequently, while gay neighborhoods may become less gay, other neighborhoods may also become more gay.
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Hapiot, F., and E. Monflier. "Cyclodextrin-Promoted Nucleophilic Opening of Oxiranes." In Water in Organic Synthesis. Georg Thieme Verlag KG, 2012. http://dx.doi.org/10.1055/sos-sd-206-00566.

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Whittington, Richard. "Open Strategy." In Opening Strategy. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780198738893.003.0007.

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This chapter examines the development of open strategy practices from the late 1990s. Open strategy involves greater transparency about strategy to internal and external audiences, and greater inclusion for internal and external stakeholders. The contemporary rise of open strategy is supported by three exogenous forces: the dissolving of organizational boundaries internally and externally, a newly democratic working culture, and new technologies, especially social media. Nevertheless, open strategy’s development still involves two kinds of arduous and fallible institutional work: ‘rule-making’ and ‘resource-organizing’. As examples of the first, Gary Hamel’s Strategos Consulting promoted new kinds of democratic strategy norms, while corporates such as IBM developed internal openness through its jams. Under the second, new consulting firms were created such as Global Business Network, while established corporations such as Barclays Bank, Nokia, and Shell had to organize new kinds of participative strategy process.
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Whittington, Richard. "Strategic Planning." In Opening Strategy. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780198738893.003.0005.

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This chapter examines the development of strategic planning practices from around 1960. Strategic planning advanced on the prior practice of long-range planning by emphasizing choice, competition, and control. It also made an initial step towards more open forms of strategizing by widening the discourse of strategy among managerial elites. Strategic planning’s rise was supported by three exogenous forces: growing organizational complexity, a culture of rationality, and new analytical technologies. Nevertheless, strategic planning’s development still took two kinds of arduous and fallible institutional work: ‘rule-making’ and ‘resource-organizing’. Under the first, corporate strategists, such as Shell’s Pierre Wack, created and disseminated techniques, such as scenario analysis, while consultants, such as BCG and McKinsey, promoted portfolio analysis. Under the second, entrepreneurs, such as Bruce Henderson, had to create new consulting organizations, such as BCG, and corporate strategists, such as Jack McKitterick at General Electric, built the first corporate strategy units.
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Whittington, Richard. "Strategic Management." In Opening Strategy. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780198738893.003.0006.

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This chapter examines the development of strategic management practices from the late 1970s. Strategic management advanced on the prior practices of strategic planning by emphasizing change and implementation. It also opened up the strategy process by decentralizing responsibilities and including employees in implementation. Strategic management’s rise was supported by three exogenous forces: growing pressure on big organizations to change, a new managerial culture of responsibility and learning, and new communication and participation technologies. Nevertheless, strategic planning’s development still took two kinds of arduous and fallible institutional work: ‘rule-making’ and ‘resource-organizing’. Under the first, Shell for example developed a version of strategic management as involving managerial conversation and learning, while McKinsey promoted strategic management as involving decentralization. Under the second, new consulting firms such as Gemini were created and large corporate investments in management training were made, as at General Electric’s Crotonville facility.
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"5 Outward Reforming and Inward Opening to Promote Industrial Upgrading." In China under Xi Jinping. BRILL, 2015. http://dx.doi.org/10.1163/9789004291645_007.

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Conference papers on the topic "Promoter opening"

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LI, LINGYAN. "ECONOMIC DEVELOPMENT DIRECTION AND SUGGESTIONS OF HEILONGJANG PROVINCE UNDER THE NEW DEVELOPMENT PATTERN." In CONTEMPORARY ECONOMIC PROBLEMS OF RUSSIA AND CHINA. Amur State University, 2021. http://dx.doi.org/10.22250/medprh.5.

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In May 2020, China has put forward a major development strategy of the Developing-mode of Economic Circulation Between Domestic and International”, China's opening to the general public or outside world will continue in the future. But the emphasis on foreign investment is no longer to open up for the sake of opening up. The ultimate purpose of expanding export and foreign investment is to meet the needs of the domestic market. Developing and upgrading the domestic market is the focus of the future. In the future, China's opening up will be at a higher level, and mutual benefit and win-win wit
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Watson, Travis B., Kyle R. Vinton, Lesley M. Wright, Daniel C. Crites, Mark C. Morris, and Ardeshir Riahi. "Influence of Hole Inlet Geometry on the Film Cooling Effectiveness From Shaped Film Cooling Holes." In ASME Turbo Expo 2019: Turbomachinery Technical Conference and Exposition. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/gt2019-92057.

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Abstract The effect of film cooling hole inlet geometry is experimentally investigated in this study. Detailed film cooling effectiveness distributions are obtained on a flat plate using Pressure Sensitive Paint (PSP). The inlet of a traditional 12°-12°-12°, laidback, fanshaped hole varies from a traditional “round” opening to an oblong, racetrack shaped opening. In this study, a single racetrack inlet with an aspect ratio of 2:1 is compared to the round inlet. For both designs, the holes are inclined at θ = 30° relative to the mainstream. Blowing ratios of 0.5, 1.0, and 1.5 are considered as
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An, Chang-Fa, Seyed Mehdi Alaie, and Michael S. Scislowicz. "Impact of Cavity on Sunroof Buffeting: A Two Dimensional CFD Study." In ASME/JSME 2004 Pressure Vessels and Piping Conference. ASMEDC, 2004. http://dx.doi.org/10.1115/pvp2004-3099.

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Driven by fluid dynamics principles, the concept for buffeting reduction, a cavity installed at the leading edge of the sunroof opening, is analyzed. The cavity provides a room to hold the vortex, shed from upstream, and prevents the vortex from escaping and from directly intruding into the cabin. The concept has been verified by means of a two dimensional simulation for a production SUV using the CFD software — FLUENT. The simulation results show that the impact of the cavity is crucial to reduce buffeting. It is shown that the buffeting level may be reduced by 3 dB by adding a cavity to the
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Guy, Ryan K., and Rudolf H. Stanglmaier. "Steady-State Intake Flow in a High-Performance V-Twin Engine." In ASME 2006 Internal Combustion Engine Division Spring Technical Conference. ASMEDC, 2006. http://dx.doi.org/10.1115/ices2006-1326.

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The design of intake ports for high-performance internal combustion engines has traditionally relied on steady-state flow benches and prototype core boxes. In this study, Computational Fluid Dynamics (CFD) methods were employed to gain further insight into the characteristics of a high-performance motorcycle engine. In this particular engine configuration, the throttle is located in very close proximity to the intake port, and the effects of throttle position on the intake flow characteristics were examined. This study shows that steady-state CFD analysis can be used in combination with tradit
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Hernández Navarro, Patricia. "Design of information systems as an aid to migrants." In Systems & Design: Beyond Processes and Thinking. Universitat Politècnica València, 2016. http://dx.doi.org/10.4995/ifdp.2016.3218.

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Starting from the official announcement called by the International Committee of the Red Cross and the Universidad Iberoamericana’s Program on Migration for the 1st Contest “Let us help those who aid migrants”, students of the degree course on Graphic Design and an interdisciplinary group of teachers developed a “visual communication system to promote hygiene and health in hostels lodging migrants in transit.”[1] Through the use of a dialectical – reflexive methodology[2] it was possible to implement the reasonable development of a common language for the different disciplines intervening in t
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Teixeira, José C. F., Senhorinha F. C. F. Teixeira, Pedro Cunha, and Angela M. Silva. "Thermal Driven Dispersion of Smoke in a Parking Space." In ASME 2016 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/imece2016-67498.

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Multi store parking spaces are complex buildings that pose specific problems to hazard management resulting from fire and pollutant release from the exhaust gases of automobiles. They are often characterized by large open spaces which do not prevent the spread of fire and smoke. The presence of large quantities of fuel just adds to the risk. In addition, the random occupancy of the space and existence of large openings make difficult the hazard containment. Structural details such as columns and beams can facilitate the accumulation of smoke in pockets. A combination of fire resistant doors an
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Trembošová, Miroslava, Alena Dubcová, and Natália Horná. "Retail and shopping behavior in small towns in Slovakia (example study of Zlaté Moravce town)." In 27th edition of the Central European Conference with subtitle (Teaching) of regional geography. Masaryk University Press, 2020. http://dx.doi.org/10.5817/cz.muni.p210-9694-2020-17.

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In the past 15 years we have been involved in the rapid development of retail in Slovakia. Its globalization trends, materialized in shopping malls, often built on a 'green field' along major communication lines, have had a significant impact on commercial suburbanization. The “pulling” of large-scale retail centers on the outskirts of the city significantly affects the state and further development in the central part of the city, with frequent consequences (deadening) of traditional retail zones, many times leading to their disappearance. The new shopping zones change the mode of the time fu
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Zhu, Mingmin, Xiaoqing Qiang, and Jinfang Teng. "Numerical Investigation on Slot Casing Treatment in a Transonic Axial Compressor Stage: Part 2 — Unsteady Simulations and Analysis." In ASME 2016 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/imece2016-65261.

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Slot-type casing treatment generally has a great potential of enhancing the operating range for tip-critical compressor rotors, however, with remarkable efficiency drop. In the first part of this two-part words, several configurations of slot casing treatment were tested in a 1.5 transonic compressor stage by steady simulations. One kind of arc-curve skewed slot contributed to considerable stall margin improvement with minimum efficiency loss. However, interaction between main passage and casing treatment was inherently unsteady. Steady simulation was inadequate to provide accurate compressor
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Ramos Gurjao, Kildare George, Eduardo Gildin, Richard Gibson, and Mark Everett. "Mechanistic Modeling of Distributed Strain Sensing DSS and Distributed Acoustic Sensing DAS to Assist Machine Learning Schemes Interpreting Unconventional Reservoir Datasets." In SPE Annual Technical Conference and Exhibition. SPE, 2021. http://dx.doi.org/10.2118/206049-ms.

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Abstract The use of fiber optics in reservoir surveillance is bringing valuable insights to fracture geometry and fracture-hit identification, stage communication and perforation cluster fluid distribution in many hydraulic fracturing processes. However, given the complexity associated with field data, its interpretation is a major challenge faced by engineers and geoscientists. In this work, we propose to generate Distributed Strain/Acoustic Sensing (DSS/DAS) synthetic data of a cross-well fiber deployment that incorporate the physics governing hydraulic fracturing treatments. Our forward mod
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Dinovitzer, Aaron S., Brian A. Graville, and Alan G. Glover. "Strain-Based Failure Criteria for Sharp Part-Wall Defects in Pipelines." In 1998 2nd International Pipeline Conference. American Society of Mechanical Engineers, 1998. http://dx.doi.org/10.1115/ipc1998-2031.

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Failure criteria in current engineering critical assessment procedures for defects in pipelines and welds are stress-based. For example, failure is presumed to occur when the net section average stress reaches some arbitrary flow stress. These approaches are unrealistic for defects of limited length where loading of the net section (ligament) is essentially strain controlled. In order to improve upon this, the authors developed a strain-based failure criterion for part wall pipe defects in terms of the maximum ligament plastic extension. While this criterion[l] provided a basis for assessing t
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Reports on the topic "Promoter opening"

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Oza, Shardul, and Jacobus Cilliers. What Did Children Do During School Closures? Insights from a Parent Survey in Tanzania. Research on Improving Systems of Education (RISE), 2021. http://dx.doi.org/10.35489/bsg-rise-ri_2021/027.

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In this Insight Note, we report results of a phone survey that the RISE Tanzania Research team conducted with 2,240 parents (or alternate primary care-givers) of primary school children following the school closures in Tanzania. After the first case of COVID-19 was confirmed in Tanzania on 16 March 2020, the government ordered all primary schools closed the following day. Schools remained closed until 29 June 2020. Policymakers and other education stakeholders were concerned that the closures would lead to significant learning loss if children did not receive educational support or engagement
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Lazonick, William, Philip Moss, and Joshua Weitz. The Unmaking of the Black Blue-Collar Middle Class. Institute for New Economic Thinking Working Paper Series, 2021. http://dx.doi.org/10.36687/inetwp159.

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In the decade after the Civil Rights Act of 1964, African Americans made historic gains in accessing employment opportunities in racially integrated workplaces in U.S. business firms and government agencies. In the previous working papers in this series, we have shown that in the 1960s and 1970s, Blacks without college degrees were gaining access to the American middle class by moving into well-paid unionized jobs in capital-intensive mass production industries. At that time, major U.S. companies paid these blue-collar workers middle-class wages, offered stable employment, and provided employe
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