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Journal articles on the topic 'Propofol Etomidate Blood Sugar'

Author: Grafiati

Published: 3 June 2025

Last updated: 1 August 2025

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1

Raina, Parul, Smriti Gulati, Vrinda Chauhan, and Anita Vig. "Comparative study of propofol and etomidate as intravenous induction agents for general anesthesia: hemodynamic effects, adrenal suppression, and blood glucose response in controlled hypertensive patients." International Journal of Research in Medical Sciences 11, no. 11 (2023): 4142–46. http://dx.doi.org/10.18203/2320-6012.ijrms20233389.

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Background: General anesthesia induces unconsciousness and loss of reflexes, facilitating complex medical treatments. The induction of anesthesia is crucial for patient comfort and procedural success, with propofol and etomidate being common intravenous induction agents. Propofol offers a rapid onset and short duration, while etomidate is known for cardiovascular stability. Methods: A prospective randomized controlled trial involving 100 controlled hypertensive patients compared propofol and etomidate for induction. Hemodynamic parameters and biochemical responses were monitored at various int

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Dhanjit Borah Pollov, Das. "Comparison of Hemodynamic Changes and Blood Sugar Levels between Etomidate and Propofol Before and after Induction of General Anaesthesia." International Journal of Science and Research (IJSR) 12, no. 2 (2023): 1614–18. http://dx.doi.org/10.21275/mr23213115001.

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Singhal, Shakti. "COMPARATIVE STUDY OF HAEMODYNAMIC CHANGES AND BLOOD SUGAR LEVELS BEFORE AND AFTER INDUCTION OF GENERAL ANAESTHESIA WITH ETOMIDATE AND PROPOFOL." International Journal of Advanced Research 6, no. 5 (2018): 721–26. http://dx.doi.org/10.21474/ijar01/7088.

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Viburajah, Vidarshna, and Venkatesh Selvaraj. "Comparative Evaluation of Effect of Propofol, Etomidate and a Combination of Propofol and Etomidate on the Hemodynamic Response to Induction and Endotracheal Intubation: A Prospective Randomized Double Blinded Study." Journal of Anesthesiology and Reanimation Specialists' Society 32, no. 1 (2024): 20–26. http://dx.doi.org/10.54875/jarss.2024.68736.

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Objective: Earlier studies have shown favorable hemodynamics with etomidate compared to propofol. Our study aimed to compare the hemodynamic characteristics of intravenous induction with precalculated doses of propofol, etomidate, and a combination of propofol-etomidate in adult surgical patients. Methods: One hundred twenty six patients aged 18 to 50 years of either sex and ASA physical status I scheduled for various surgeries under general anesthesia were recruited. Patients were randomized into three groups. Group P-induced with pre-calculated propofol (2 mg kg-1) intravenous, Group E with

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Rayamajhi, Mallika, Puja Thapa, Anjan Khadka, Biswa Ram Amatya, and Udaya Bajracharya. "Comparative Study of Propofol and Etomidate on the Haemodynamic Effects During Induction and Endotracheal Intubation." Medical Journal of Shree Birendra Hospital 18, no. 2 (2019): 7–15. http://dx.doi.org/10.3126/mjsbh.v18i2.20907.

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Introduction: While most intravenous induction agents decrease arterial blood pressure, laryngoscopy and endotracheal intubation increase the heart rate and blood pressure. Propofol causes a decrease in systemic blood pressure whereas etomidate has minimal effects on the cardiovascular system. This study aims to evaluate and compare the hemodynamic effects of propofol and etomidate during induction and endotracheal intubation. Methods: 62 ASA I and II patients, 20-60 years of age, scheduled for elective surgery were enrolled in this prospective, randomised and double blind comparative st

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Meghraj, Dr Mittal A., Dr Jigarkumar B. Gosai, Dr Chirag J. Patel, Dr Arunjith G, Dr Himanshu Dhanrajbhai Ramchandani, and Dr Pathan Uzma Parvin. "A comparative study of etomidate and propofol as induction agent for intubation in patients coming to emergency medicine department." BJKines National Journal of Basic & Applied Sciences 15, no. 02 (2023): 110–14. http://dx.doi.org/10.56018/20231217.

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Background & Aims: An ideal induction agent for intubation in the emergency department should have hemodynamic stability, minimal respiratory side effects and rapid clearance. Etomidate and Propofol are popular rapid-acting inducing agents; our aim is to compare hemodynamic changes and adverse effects occurring between them when used as induction agents in the emergency department. Material and Methods: A study sample of 200 patients who required intubation in the emergency department were enrolled after satisfying the inclusion and exclusion criteria and were divided into two equal groups

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Nilesh, Kadu, and Agaskar R.D. "Comparative Evaluation of Propofol and Etomidate for LMA Insertion Ease and Hemodynamic Stability: A Randomised Controlled Trail." International Journal of Pharmaceutical and Clinical Research 16, no. 2 (2024): 847–53. https://doi.org/10.5281/zenodo.11074972.

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<strong>Background: </strong>Supraglottic airway devices, like the laryngeal mask airway (LMA), have become integral in airway management. While propofol is commonly used for LMA insertion, its dosage can lead to hemodynamic instability. This study investigates the effectiveness of propofol versus etomidate, each in combination with fentanyl and midazolam, aiming to optimize LMA insertion while preserving cardiovascular stability. <strong>Methods:</strong> In a randomized trial, 60 ASA I & II patients were allocated to Propofol (P) or Etomidate (E) groups. Both received stan

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Dutta, Utpal, Shahbaz Bin Sabir, and Rituparna Bora. "Comparison of Cardiovascular Response during Induction of General Anaesthesia Using Etomidate Versus Using Propofol under Bispectral Index Guidance in a Tertiary Care Medical College, Dibrugarh." Journal of Evolution of Medical and Dental Sciences 10, no. 32 (2021): 2645–51. http://dx.doi.org/10.14260/jemds/2021/541.

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BACKGROUND The present study was done to compare the cardiovascular responses of etomidate and propofol as induction agents of general anaesthesia under Bispectral index (BIS) guidance and evaluate the effect of intravenous induction agent etomidate and propofol on the variation in heart rate and blood pressure during induction of general anaesthesia. METHODS This is a prospective randomized and double blinded comparative study done in Assam Medical College and Hospital on patients scheduled for elective surgeries under general anaesthesia from June 2019 to May 2020. 80 patients were randomly

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Zhi, Y., and W. Li. "Effects of total intravenous anesthesia with etomidate and propofol on postoperative cognitive dysfunction." Physiological Research, Vol 72(2) (April 30, 2023): 251–58. http://dx.doi.org/10.33549/physiolres.934983.

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Increased incidence of postoperative cognitive dysfunction (POCD) is observed in elderly patients underwent intravenous anesthesia (TIVA) with endotracheal intubation. Modulation of anesthetics compatibility may reduce the severity of POCD. Elderly patients scheduled for TIVA with endotracheal intubation were randomly divided into the control group (1.00‑2.00 mg/kg propofol) and the etomidate and propofol combination group (1.00‑2.00 mg/kg propofol and 0.30 mg/kg etomidate). Serum cortisol, S100β, and neuron-specific enolase (NSE), interleukin (IL)-6, and IL-10 were monitored during or after t

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Deepa, Yadav, Vijay Santushti, Kanwat Jyoti, and Kumari Brijesh. "A Prospective Randomized Study of Etomidate and Propofol Induction on Hemodynamic Response in Patients Undergoing Short Surgical Procedures with Laryngeal Mask Airway." International Journal of Toxicological and Pharmacological Research 13, no. 9 (2023): 53–60. https://doi.org/10.5281/zenodo.11079456.

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<strong>Objective: </strong>This study was done to compare Etomidate and Propofol as inducing agent in general anaesthesia for laryngeal mask airway with following objectives. To evaluate and compare haemodynamic parameters between the two groups and compare the ease of insertion of laryngeal mask airway. <strong>Methods: </strong>Prospective randomized single blind controlled study was conducted in 90 patients of either sex in the age group of 20-60 years of ASA grade I or II scheduled for short surgical procedures with LMA insertion under general anaesthesia. Patients were ran

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Deepa, Yadav, Vijay Santushti, Kanwat Jyoti, and Kumari Brijesh. "A Prospective Randomized Study of Etomidate and Propofol Induction on Hemodynamic Response in Patients Undergoing Short Surgical Procedures with Laryngeal Mask Airway." International Journal of Toxicological and Pharmacological Research 13, no. 9 (2023): 120–27. https://doi.org/10.5281/zenodo.11080468.

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<strong>Objective: </strong>This study was done to compare Etomidate and Propofol as inducing agent in general anaesthesia for laryngeal mask airway with following objectives. To evaluate and compare haemodynamic parameters between the two groups and compare the ease of insertion of laryngeal mask airway. <strong>Methods: </strong>Prospective randomized single blind controlled study was conducted in 90 patients of either sex in the age group of 20-60 years of ASA grade I or II scheduled for short surgical procedures with LMA insertion under general anaesthesia. Patients were ran

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Suneetha, Dadi, Nimmagadda Rajaratnakumar, Sunkesula Bharat Kumar, Krishna Saketh Athmakuri, Syeda Farozan Quadri, and Shalmala Vani. "Comparison of hemodynamic stability of propofol ketamine versus etomidate ketamine during induction in peritonitis cases posted for emergency surgery." EUREKA: Health Sciences, no. 2 (March 31, 2023): 33–39. http://dx.doi.org/10.21303/2504-5679.2023.002914.

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The aim: The aim of the present study is to evaluate the hemodynamic stability of propofol ketamine versus etomidate ketamine during induction of anaesthesia in peritonitis cases posted for emergency surgery. Methods: Sixty patients with peritonitis, posted for emergency surgery under general anaesthesia, were randomly allocated to two groups. Group propofol ketamine (P + K) comprised of 30 patients (n=30) were induced with propofol 1 mg/kg and ketamine 0.75 mg/kg IV. Group etomidate ketamine (E + K) comprised 30 patients induced with etomidate 0.3 mg/kg and ketamine 0.75 mg/kg. The hemo

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Carpenter, Dharmendra, Brijesh Soni, Pradeep Kumar Goyal, and Mukesh Godara. "Comparison of hemodynamic effects of etomidate and propofol as an induction agent in patients with LVEF 40% undergoing elective coronary artery bypass grafting surgery – A prospective and randomized study." Indian Journal of Clinical Anaesthesia 8, no. 2 (2021): 250–56. http://dx.doi.org/10.18231/j.ijca.2021.048.

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This study aims to compare the hemodynamic response of two commonly used induction agents Propofol and Etomidate in patients with left ventricular ejection fraction ≤40% undergoing Coronary Artery Bypass Grafting surgery. To compare the effects of Propofol and Etomidate on hemodynamics in terms of heart rate, rhythm, blood pressure, and central venous pressure. Narayana Multispeciality Hospital, Jaipur. Prospective, double-blinded, randomized, hospital based study.100 patients with LVEF≤40% scheduled for elective CABG, were randomly assigned to one of the two groups receiving either of the ind

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Liu, Yanlong, Yihong Qian, Lilan Zhang, et al. "Comparative efficacy and safety of ciprofol, propofol, and propofol and etomidate mixture, and ciprofol and etomidate mixture in patients undergoing painless gastroscopy: A randomized, double-blind controlled clinical trial." Medicine 103, no. 36 (2024): e39585. http://dx.doi.org/10.1097/md.0000000000039585.

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Background: To compare the efficacy and safety of ciprofol, propofol, propofol and etomidate mixture or ciprofol and etomidate mixture in patients undergoing painless gastroscopic anesthesia, and to explore the optimal plan to relieve the patient’s discomfort. Methods: A total of 120 patients scheduled for painless gastroscopy were randomly assigned to 4 groups: propofol (Group P), ciprofol (Group C), propofol-etomidate mixture (Group P-E), and ciprofol-etomidate mixture (Group C-E). The success rate of gastroscopy examination, patient satisfaction, incidence of injection pain, hemodynamic par

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Amisha, Singh Keshav, Awasya Sonal, Ali Khan Tahir, and Soni Ayushi. "To Evaluate the Effect of Intravenous Induction Agent Etomidate and Propofol on Hemodynamic Stress Response to Laryngoscopy and Endotracheal Intubation in General Anaesthesia." International Journal of Pharmaceutical and Clinical Research 16, no. 10 (2024): 42–45. https://doi.org/10.5281/zenodo.14030836.

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<strong>Background & Methods:</strong> The aim of the study is to evaluate the effect of intravenous induction agent ETOMIDATE and PROPOFOL on hemodynamic stress response to laryngoscopy and endotracheal intubation in General Anaesthesia. Patient was kept nil per oral instructions 8 hours prior to the surgery. After shifting the patient to the operating room, non-invasive blood pressure, five leads electrocardiography and pulse oximetry were connected to patient and baseline vitals heart rate, Mean arterial pressure, oxygen saturation of patient were recorded after 5 mins settling in

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Ramakrishna, Saraswathi, Langpoklakpam Chaoba Singh, Bijaya Chingtham, and Rahul Jain. "Comparative Study of Effect of Etomidate Versus Propofol plus Ketamine on Haemodynamic Response to Laryngoscopy and Endotracheal Intubation." Journal of Evidence Based Medicine and Healthcare 8, no. 15 (2021): 939–44. http://dx.doi.org/10.18410/jebmh/2021/182.

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BACKGROUND Laryngoscopy and endotracheal intubation, a painful procedure, frequently used in airway management is commonly associated with undesired haemodynamic changes like hypertension, tachycardia and arrythmias. Thus, this study was designed to compare haemodynamic stability to laryngoscopy and intubation using single drug induction with etomidate and combined drug induction with propofol and ketamine. METHODS This was a double blind randomised controlled trial, a total of 90 patients of both sexes, aged between 18 - 60 years, who were scheduled for elective surgeries under general anaest

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Chauhan, Renu, Kavita Lalchandani, and M. R. Upadhyay. "To compare the hemodynamic effects of the infusion of both intravenous induction anaesthetic agents Etomidate and Propofol under bispectral index guidance." Indian Journal of Clinical Anaesthesia 8, no. 3 (2021): 428–35. http://dx.doi.org/10.18231/j.ijca.2021.082.

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Intravenous anaesthetic agents are preferred to induce anaesthesia in day to day practice because of rapid and smoother action with fewer risks. An ideal induction agent for general anaesthesia should have hemodynamic stability, minimal respiratory side effects and rapid clearance. This is a prospective, randomised, single blind, control study of total 60 patients.This study was carried out in Department of Anaesthesiology, at a Tertiary Care Teaching Hospital over a period of 1 year. In this study, a total of 60 patients undergoing elective surgery under general anaesthesia were randomized in

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Liu, Ji, Jinqiu Yang, Xiyang Yang, et al. "Application of dexmedetomidine combined with propofol–etomidate mixture in radical gastrectomy under general anesthesia." Medicine 103, no. 44 (2024): e39669. http://dx.doi.org/10.1097/md.0000000000039669.

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Background: Gastric cancer is the third most common malignant tumor with the second highest mortality rate in the world, and radical gastrectomy is the main treatment method, but the operation needs a long period of time to carry out and has strong surgical trauma stimulation, which is likely to cause sympathetic nerve excitement and stress reaction in the body. Therefore, the selection of appropriate anesthetic medication regimen and anesthesia method has an important impact on the intraoperative management and postoperative recovery of patients. This study aims to compare the clinical effect

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J., Vasanthy, Indira Gandhi J., Balaji G., and Maheswari N. "Haemodynamic Responses to Tracheal Intubation using Propofol, Etomidate, and Etomidate –Propofol Combination in Anaesthesia Induction." International Journal of Pharmaceutical and Clinical Research 16, no. 7 (2024): 1615–22. https://doi.org/10.5281/zenodo.13364465.

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<strong>Background: </strong>Haemodynamic changes during laryngoscopy and intubation are the major concern during induction under general anaesthesia. This study aims to compare the effects between inj PROPOFOL, inj ETOMIDATE and inj ETOFOL (etomidate and propofol) during induction and intubation in elective surgeries. <strong>Objectives:</strong> To evaluate and assess the effects of the 3 different induction agents, on the variation in heart rate (HR) and mean arterial pressure (MAP) were noted. They are baseline (T1), after induction (T2), before intubation (T3) and immediate

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Solanki, Kinjal M., Kinna G. Shah, Dipesh P. Shah, and Jayshreeben M. Thakkar. "Comparison of etomidate and propofol as an induction agent to study hemodynamic effects and serum cortisol level following endotracheal intubation in hypertensive patients." International Journal of Basic & Clinical Pharmacology 13, no. 1 (2023): 85–90. http://dx.doi.org/10.18203/2319-2003.ijbcp20233897.

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Background: The present study aimed to compare hemodynamic parameters (heart rate, blood pressure) and adverse effects (injection pain, myoclonus, postoperative nausea/vomiting) between Etomidate and propofol groups. Methods: Patients were divided into two groups: Etomidate Group E and a Propofol Group P. All hemodynamic data were measured during induction, intubation, and post-intubation up to 15 min. Intravenous cortisol levels were measured at baseline, just after induction and at 24 hours after induction. Results: At 3 min and 5 min SBP was decreased by 22.04% and 18.39% in Group P. At 3 m

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Pooja, Fumakiya, Makwana Khyati, and Mer Jagdishbhai. "Comparative Analysis of Hemodynamic Variability and Level of Blood Cortisol while Induction with Propofol and Etomidate." International Journal of Pharmaceutical and Clinical Research 15, no. 7 (2023): 1618–23. https://doi.org/10.5281/zenodo.12005276.

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<strong>Background and Aim: </strong>The selection of an anesthetic for inducing anaesthesia is primarily based on its pharmacodynamic characteristics. One of the most often used drugs for inducing general anaesthesia is propofol, or 2,6-diisopropyl phenol. The goal of the current study is to determine how serum cortisol levels, hemodynamic parameters, discomfort during injection, myoclonus, and apnea during induction affect patients undergoing laproscopic cholecystectomies. <strong>Material and Methods:</strong> A prospective, randomized, double-blind clinical trial was used in

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Chang, Pan, YongWei Su, DeYing Gong, et al. "The preclinical pharmacological study of a novel intravenous anesthetic, ET-26 hydrochloride, in aged rats." PeerJ 10 (September 29, 2022): e13995. http://dx.doi.org/10.7717/peerj.13995.

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Background ET-26 hydrochloride (ET-26HCl) is a novel analogue of etomidate approved for clinical trials. However, all results from recent studies were accomplished in young adult animals. The objective of this study was to evaluate the efficacy and safety of ET-26HCl in aged rats. Methods Aged Sprague-Dawley rats were randomly divided into three groups (three males and three females in each group) were given dose of two-fold of median effective dose (ED50) of ET-26HCl, etomidate and propofol: the measurements of loss of the righting reflex (LORR) and cardiovascular and respiratory function aft

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Deepesh, Manoj Kumar Chaurasiya, Anil Kumar Verma, and Apurva Agarwal. "Observation of hemodynamic variability and level of blood cortisol while induction with propofol and etomidate: A prospective, randomized, double blind study." Indian Journal of Clinical Anaesthesia 9, no. 2 (2022): 179–84. http://dx.doi.org/10.18231/j.ijca.2022.037.

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: To observe the effects of propofol and etomidate induction on patients undergoing laproscopic cholecystectomies regarding serum cortisol level, hemodynamic parameters, pain on injection, myoclonus, and apnea on induction.: It is a prospective, randomized, double blind study. After approval from Institute Ethics Committee, sixty patients of age between 18 and 60 years with ASA grade I and II scheduled for laproscopic cholecystectomy under general anesthesia were randomly divided into two groups: Group A (n=30) would receive injection propofol 2 mg/kg i.v., Group B (n=30) would receive injecti

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Wilbur, Kerry, and Peter J. Zed. "Is propofol an optimal agent for procedural sedation and rapid sequence intubation in the emergency department?" CJEM 3, no. 04 (2001): 302–10. http://dx.doi.org/10.1017/s1481803500005819.

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ABSTRACTObjective:We conducted a qualitative systematic review to evaluate the efficacy and safety of propofol for direct current cardioversion (DCC), rapid sequence intubation (RSI) and procedural sedation in adult emergency department (ED) patients.Data source:MEDLINE (1966 to September 2000), PubMed (to September 2000), EMBASE (1988 to September 2000), Database of Systematic Reviews (to September 2000), Best Evidence (1991 to September 2000) and Current Contents (1996 to September 2000) databases.Study selection:English-language, randomized, comparative evaluations of propofol for procedure

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LaRochelle, Joseph M., Bonnie Desselle, and Janet L. Rossi. "Continuous-Infusion Etomidate in a Patient Receiving Extracorporeal Membrane Oxygenation." Journal of Pediatric Pharmacology and Therapeutics 22, no. 1 (2017): 65–68. http://dx.doi.org/10.5863/1551-6776-22.1.65.

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We describe a 16-year-old, 65-kg male deployed on extracorporeal membrane oxygenation (ECMO) for refractory respiratory failure secondary to ingestion of multiple substances. During his ECMO course, standard sedative and analgesic strategies failed and alternative medications were used. The patient received various dosages of fentanyl, morphine, hydromorphone, clonidine patches, dexmedetomidine, lorazepam, methadone, pentobarbital, olanzapine, and propofol. Despite administration of multiple agents, on day 29 of ECMO the patient experienced elevated blood pressures due to agitation, and contin

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Larsen, Brita, Gudrun Hoff, Wolfram Wilhelm, Heiko Buchinger, Guido A. Wanner, and Michael Bauer. "Effect of Intravenous Anesthetics on Spontaneous and Endotoxin-stimulated Cytokine Response in Cultured Human Whole Blood." Anesthesiology 89, no. 5 (1998): 1218–27. http://dx.doi.org/10.1097/00000542-199811000-00023.

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Background Various anesthetics have been suggested to interfere with the immune system. The ability of leukocytes to express surface receptors and mediators is fundamental to a successful host defense. Therefore, the effects of intravenous anesthetics on cytokine release by leukocytes and expression of surface molecules known to modulate this response were determined. Methods Concentration-dependent effects of thiopentone, etomidate, propofol, ketamine, midazolam, and fentanyl on spontaneous and endotoxin (lipopolysaccharide; 1 microg/ml)-stimulated cytokine release were studied in whole blood

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Angelats, M., A. Leila, C. David, et al. "Description of anesthetic drugs used in hospital del Mar and their impacts on convulsion duration and blood pressure in electroconvulsive therapy." European Psychiatry 41, S1 (2017): S373. http://dx.doi.org/10.1016/j.eurpsy.2017.02.388.

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IntroductionThe electroconvulsive therapy (ECT) is an effective treatment used for several psychiatric disorders. However, there are multiple enigmas about the mechanisms of action and factors that improve its results. Some frequent questions are if the anesthetic drug makes a difference in the time of convulsion and blood pressure.AimsOur principal aim is to describe the utilization of anesthetic drugs among the patients that are being treated with ECT in hospital del Mar. We also want to know the differences in the time of convulsion and systolic arterial pressure for every anesthetic drug (

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V. Hemanth, K. Jayakumar, S. Senthil kumar, and K. Kannan. "COMPARATIVE EVALUATION OF CARDIOVASCULAR PARAMETERS OF PROPOFOL / ETOMIDATE FOR ABDOMINAL SURGERIES IN CALVES." Indian Journal of Veterinary and Animal Sciences Research 53, no. 4 (2024): 85–89. http://dx.doi.org/10.56093/ijvasr.v53i4.158011.

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The calves presented with abdominal affections requiring surgical interventions were randomly divided into group I and group II with seven animals in each group. All the animals were premedicated with dexmedetomidine at 2 µg/kg body weight, pentazocine at 1 mg/kg body weight and midazolam at 0.2 mg/kg body weight intravenously. In group I and group II, anaesthetic induction was carried out with propofol at 2 mg/kg body weight and etomidate at 0.25 mg/kg body weight intravenously, respectively. Both the groups were maintained in Isoflurane anaesthesia with modified oro-endotracheal tube. The ca

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Nwaneshiudu, Ikechukwu C., Chinwe A. Nwaneshiudu, and Daniel T. Schwartz. "Separation and Enhanced Detection of Anesthetic Compounds Using Solid Phase Micro-Extraction (SPME)–Raman Spectroscopy." Applied Spectroscopy 68, no. 11 (2014): 1254–59. http://dx.doi.org/10.1366/13-07362.

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Polydimethylsiloxane (PDMS)-based solid-phase micro-extraction (SPME) was used along with Raman spectroscopy (RS) to separate and enhance the detection of five anesthetic compounds (halothane, propofol, isoflurane, enflurane, and etomidate) from aqueous and serum phases. Raman signals in the spectral ranges 250–450 cm−1 and 950–1050 cm−1 allowed the unique characterization of all five compounds when extracted into the PDMS phase. The SPME-RS detection of clinically relevant concentrations of aqueous propofol (6.5 μM) and halothane (200 μM) is shown. We quantify the partition coefficient for aq

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Vansola, Reema H., Ramila H. Jamliya, Divya D. Toshaniwal, and Milind J. Mevada. "Comparative study of thiopentone sodium, propofol, etomidate for anesthetic efficacy & effect on seizure duration in electroconvulsive therapy." Indian Journal of Clinical Anaesthesia 8, no. 2 (2021): 288–93. http://dx.doi.org/10.18231/j.ijca.2021.054.

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Electroconvulsive treatment (ECT) is an entrenched mental treatment where seizures are electrically actuated in patients for restorative impacts. ECT can deliver extreme unsettling influences in the cardiovascular framework most generally a transient time of hypertension & changes in the pulse and a stamped increment in cerebral blood stream and intracranial weight. These hemodynamics changes might be adjusted utilizing different sedative medications. This investigation was attempted to think about the impacts of propofol, etomidate and thiopentone sodium utilized as IV sedative operators

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Vu, Thi Thuc Phuong, Cong Thanh Tran, and Duc Tam Bui. "Efficacy comparison of ketofol and etomidate during anesthesia induction in patients with left ventricular dysfunction undergoing coronary artery bypass graft surgery." Tạp chí Phẫu thuật Tim mạch và Lồng ngực Việt Nam 43 (August 28, 2023): 47–57. http://dx.doi.org/10.47972/vjcts.v43i.1004.

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Introduction: Anesthesia induction is a critical phase characterized by hemodynamic changes that disrupt the delicate balance between myocardial oxygen demand and supply, resulting in myocardial ischemia in patients with underlying coronary artery disease and impaired left ventricular systolic function. Consequently, maintaining stable hemodynamics during the induction process holds paramount importance. This study aims to compare the hemodynamic changes and evaluate the quality of endotracheal intubation between ketofol and etomidate during anesthesia induction for patients undergoing coronar

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Schelling, Gustav, Daniela Hauer, Shahnaz Christina Azad, et al. "Effects of General Anesthesia on Anandamide Blood Levels in Humans." Anesthesiology 104, no. 2 (2006): 273–77. http://dx.doi.org/10.1097/00000542-200602000-00012.

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Background The endocannabinoid system includes G-protein-coupled cannabinoid receptors, the endocannabinoids N-arachidonoylethanolamine (anandamide) and 2-arachidonoylglycerol, and multiple enzymes involved in the biosynthesis and degradation of endocannabinoids, including the anandamide metabolizing enzyme fatty acid amide hydrolase. Endocannabinoids play an important role in the physiologic control of sleep, pain processing, and emesis. The authors therefore investigated the effects of general anesthesia on the endocannabinoid system in humans. Methods The authors measured whole blood levels

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Kumar, Ramesh, Sooshrut Thakur, Aarti Sharma, Jyoti Pathania, and Garima Thakur. "Comparative evaluation of propofol, thiopentone and etomidate on induction time, intubation response and recovery time during laparoscopic surgery under general Anaesthesia." Indian Journal of Clinical Anaesthesia 10, no. 2 (2023): 150–57. http://dx.doi.org/10.18231/j.ijca.2023.030.

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: Optimal choice of inducing agent can partially modify the post induction hypotension, having a reported incidence of 9-40% in various studies. So, we compared the induction and recovery profile of the routinely available induction agents.This prospective randomized, comparative study was carried out on 120, ASA 1 and II patients undergoing routine laparoscopic cholecystectomy. Patient received either thiopentone 5 mg/kg, propofol 2.0 mg/kg or 0.3mg/kg injection etomidate at induction in group T, P and E respectively. The time taken from the administration of inducing agent to loss of eyelash

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Kim, Sang Hun, Sang Min Yoon, Ji Hye Ahn, and Yoon Ji Choi. "Effect of Remimazolam and Propofol on Blood Glucose and Serum Inflammatory Markers in Patients with Type 2 Diabetes: A Clinical Trial with Prospective Randomized Control." Medicina 61, no. 3 (2025): 523. https://doi.org/10.3390/medicina61030523.

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Background and Objectives: Patients with type 2 diabetes are at a higher risk of postoperative complications, such as infections, delayed wound healing, and increased mortality compared to non-diabetic patients. Materials and Methods: This prospective randomized study aims to compare the effects of two anesthetics, remimazolam and propofol, on blood glucose levels and immune function in diabetic patients undergoing surgery. Seventy-four diabetic patients undergoing general anesthesia were randomly assigned to receive either remimazolam or propofol. Plasma blood glucose levels, anti-inflammator

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Cayla, Noëlie S., Beza A. Dagne, Yun Wu, et al. "A newly developed anesthetic based on a unique chemical core." Proceedings of the National Academy of Sciences 116, no. 31 (2019): 15706–15. http://dx.doi.org/10.1073/pnas.1822076116.

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Intravenous anesthetic agents are associated with cardiovascular instability and poorly tolerated in patients with cardiovascular disease, trauma, or acute systemic illness. We hypothesized that a new class of intravenous (IV) anesthetic molecules that is highly selective for the slow type of γ-aminobutyric acid type A receptor (GABAAR) could have potent anesthetic efficacy with limited cardiovascular effects. Through in silico screening using our GABAAR model, we identified a class of lead compounds that are N-arylpyrrole derivatives. Electrophysiological analyses using both an in vitro expre

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Nasrollahi, Kobra, Khosrou Naghibi, and Leila Rezaei. "Effects of Intravenous Anesthesia on the Plasma Glucose Level During Cataract Surgery Among Patients With Type II Diabetes." Disease and Diagnosis 12, no. 1 (2022): 29–34. http://dx.doi.org/10.34172/ddj.2023.408.

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Background: High blood sugar is a typical reaction to stress. In the diabetic population, hyperglycemia can be a serious issue and has been linked to higher mortality rates. Recent studies have shown that anesthetics reduced glucose tolerance; however, it is still unclear how propofol, ketamine, and thiopental of Na affect glucose metabolism. The present study compared the blood glucose levels of thiopental of Na, ketamine, and propofol among patients with cataract surgery. Materials and Methods: The study included 135 ASA II and III adult patients of both genders who were older than 65, known

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Sourabh, Shrivastava, Sharma Ashwin, Sinha Divya, and Shrivastava Swati. "Effect of Propofol Infusion and Dexmedetomidine Fentanyl on Serum Biochemical Indices in ICU Patients." International Journal of Pharmaceutical and Clinical Research 15, no. 12 (2023): 162–66. https://doi.org/10.5281/zenodo.11185263.

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<strong>Background:</strong> Sedation plays a pivotal role in the care of the critically ill intensive care unit patient. It is equally important to assess depth of sedation. Anesthetic agents can alter the hemodynamic variables, hematological and biochemical laboratory parameters. <strong>Objectives:</strong> The purpose of this study was to compare the effect of propofol and dexmedetomidine on hemodynamic and biochemical parameters on ICU patients. <strong>Methods:</strong> This was a cross sectional study conducted in the department of Anaesthesia. Hundred ICU admit

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Sravanthi, G. N. S., and Ravi Madhusudhana. "Perioperative Management of a Patient with Prosthetic Mitral Valve Posted for Ankle Surgery." Indian Journal of Anesthesia and Analgesia 8, no. 1 (2021): 129–31. http://dx.doi.org/10.21088/ijaa.2349.8471.8121.18.

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Introduction: Patients with prosthetic valves pose a specific challenge to the anesthesiologist due to their increased predisposition to thrombo embolic events, infective endocarditis and hemolysis. Case Report: Here we describe the anaesthetic management of a 50 year old female with prosthetic mitral valve posted for wound debridement and external fixation for open type III right ankle bone fracture. She is a known case of Rheumatic heart disease and has underwent mitral valve replacement with tricuspid annuloplasty 5years back and is on oral anticoagualtion which was stopped 7days prior to s

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Kumar KR, Vasantha. "The Effects of Intravenous Propofol and Intravenous Etomidate as Induction Agents on Blood Glucose in Elective Surgeries Under General Anaesthesia: A Randomized Control Trail." Indian Journal of Anesthesia and Analgesia 7, no. 1(Part-2) (2020): 420–25. http://dx.doi.org/10.21088/ijaa.2349.8471.7120.57.

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Panggabean, Mathilda, and Yutu Solihat. "Post-General Anesthesia Angioedema After General Anesthesia." Solo Journal of Anesthesi, Pain and Critical Care (SOJA) 2, no. 1 (2022): 39. http://dx.doi.org/10.20961/soja.v2i1.59185.

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<strong>Background</strong>: General anesthesia includes the administration of avariety medicines to patient/in/ fairly short/period. Numerous negative consequences can occur because of reaction from the drugs given, one example is anaphylaxis that may lead to death if not been recognized and handled quickly &amp; promptly.<p><strong>Case Illustration:</strong><strong> </strong>A sixty-seven years old male patient 152 cm 65 kg with multiple cholecystitis and obstructive jaundice, who was scheduled to undergo laparoscopic cholecystectomy. Patient ha

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Irfan, Ahmad Siddiqui, Shaikh Neelofar, Sharma Nishtha, Mandloi Prayank, and Siddiqui Fauzia. "Comparison between Fentanyl and Nalbuphine in Blunting Hemodynamic Stress Response to Laryngoscopy and Endotracheal Intubation in Etomidate Induction of General Anesthesia." International Journal of Toxicological and Pharmacological Research 13, no. 5 (2023): 180–86. https://doi.org/10.5281/zenodo.11212597.

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<strong>Background: </strong> Propofol has a favourable pharmacokinetic and pharmacodynamic profile making it the most commonly used intravenous induction agent for general anesthesia but adverse cardiovascular effects like hypotension and bradycardia are well-documented. Therefore, hemodynamic stability associated with etomidate makes it an ideal induction agent in patients with compromised cardiac reserves. Laryngoscopy and intubation elicits a noxious stimulus, leading to intense sympathetic activity. Various drugs have been tried to attenuate this response. Opioids are known to a

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Udrea, Ana Maria, Gratiela Gradisteanu Pircalabioru, Anca Andreea Boboc, et al. "Advanced Bioinformatics Tools in the Pharmacokinetic Profiles of Natural and Synthetic Compounds with Anti-Diabetic Activity." Biomolecules 11, no. 11 (2021): 1692. http://dx.doi.org/10.3390/biom11111692.

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Diabetes represents a major health problem, involving a severe imbalance of blood sugar levels, which can disturb the nerves, eyes, kidneys, and other organs. Diabes management involves several synthetic drugs focused on improving insulin sensitivity, increasing insulin production, and decreasing blood glucose levels, but with unclear molecular mechanisms and severe side effects. Natural chemicals extracted from several plants such as Gymnema sylvestre, Momordica charantia or Ophiopogon planiscapus Niger have aroused great interest for their anti-diabetes activity, but also their hypolipidemic

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Anwar, Kanwal, Ipek Alpertugna, Danielle Detelich, et al. "Looking Beyond Diabetes: A Case of Worsening Hyperglycemia as a Manifestation of Ectopic Cushing’s Syndrome Secondary to an Adrenocorticotropic Hormone-Producing Pheochromocytoma." Journal of the Endocrine Society 5, Supplement_1 (2021): A140—A141. http://dx.doi.org/10.1210/jendso/bvab048.284.

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Abstract A 76-year-old woman presented with worsening fasting hyperglycemia on routine blood sugar measurement, previously well-controlled on Metformin, requiring initiation of insulin. Her medical history included type 2 diabetes mellitus, hypertension, and aortic stenosis. Over the next few weeks, she developed bilateral upper and lower extremity proximal muscle weakness, episodes of confusion, rapid weight loss and increasing lower extremity edema. She did not have typical Cushingoid features of moon facies, easy bruising, centripetal obesity, abdominal striae, dorsocervical fat padding, or

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Mei, Shenglan, Yifan Jia, Jinjian Zhou, et al. "Effects of Different Anesthetics on Perioperative Organ Protection and Postoperative Cognitive Function in Patients Undergoing Cardiac Valve Replacement with Cardiopulmonary Bypass." Computational Intelligence and Neuroscience 2022 (May 29, 2022): 1–6. http://dx.doi.org/10.1155/2022/8994946.

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In this paper, we have carried out an experimental study to investigate the effects of different anesthetics on perioperative organ protection and postoperative cognitive function in patients undergoing cardiac valve replacement with cardiopulmonary bypass. To realize this idea, a total of 90 patients with single valve replacement under general anesthesia and hypothermic cardiopulmonary bypass from January 2020 to October 2021 were enrolled. These patients were assigned into three groups, with 30 cases in each group by the digital table method. Group A was anesthetized with sufentanil combined

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Kuklin, V. N., J. Matri, N. P. Barlow, et al. "Current trends in management of hyperglycaemia in surgical patients with diabetes mellitus: a review." Annals of critical care, no. 4 (2021): 33–47. http://dx.doi.org/10.21320/1818-474x-2021-4-33-47.

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A large amount of clinical evidences demonstrates a clear association between long-term and/or stress-related hyperglycaemia, and development of complications after surgery. The incidences of perioperative hyperglycaemia are demonstrated in 20-80 % of all cases depending on the type of elective surgery, with the h ighest rate registered in cardiac surgery. The most studied pathophysiological complications of long-term hyperglycaemia in Diabetes Mellitus (DM) patients are; activation of the polyol pathway, diacylglycerol/protein kinase C and hexosamine pathways, advanced glycation product forma

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Fan, Shujing, and Shiduo Li. "Application Effect of Sevoflurane Combined with Nerve Block Anesthesia in Surgical Anesthesia in Patients with Uterine Fibroids." Contrast Media & Molecular Imaging 2022 (June 24, 2022): 1–7. http://dx.doi.org/10.1155/2022/9983851.

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Sevoflurane has been widely used clinically as an inhalation anesthetic. A review of domestic and domestic research, combined with the current synthesis research, pharmacological progress, existing production capacity, production, and sales status, can show that sevoflurane is a very good new type of inhalation anesthetic. Objective. To study the effect of sevoflurane combined with nerve block anesthesia on stress response and hemodynamics in patients with uterine fibroids surgery. Methods. We selected 100 cases of myomectomy patients as the research objects and divided them into observation a

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Shakti, Singhal. "COMPARATIVE STUDY OF HAEMODYNAMIC CHANGES AND BLOOD SUGAR LEVELS BEFORE AND AFTER INDUCTION OF GENERAL ANAESTHESIA WITH ETOMIDATE AND PROPOFOL." May 9, 2018. https://doi.org/10.5281/zenodo.1293650.

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Background: an ideal inducing agent for general anaesthesia should have hemodynamic stability, minimal respiratory side effects and rapid clearance. Presently intravenous drugs such as propofol and etomidate are the most safe for induction of general anaesthesia. [2-4] Methodology: in the ot patient received iv midazolam 0.03 mg/kg and iv fentanyl 2mcg/kg five minutes before induction, and was preoxygenated with 100% oxygen. Patient was induced with iv propofol at the dose of 2.5 mg/kg body weight as a induction agent @<15 sec, and iv etomidate 0.3 mg/kg body weight, for group p and group e

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Sahoo, Alok Kumar. "Clinical evaluation of effects of Intravenous Induction agents: propofol, ketamine and etomidate on blood sugar level." Journal of Medical Science And clinical Research 6, no. 1 (2018). http://dx.doi.org/10.18535/jmscr/v6i1.151.

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SHARMA, TEJASVINI, ROBINA MAKKER, PRITISH RANJAN, TENZIN KYIZOM, and SHOBIT GARG. "COMPARISON OF ETOMIDATE AND PROPOFOL AS INDUCTION AGENTS IN MODIFIED ELECTROCONVULSIVE THERAPY." Asian Journal of Pharmaceutical and Clinical Research, March 7, 2023, 57–61. http://dx.doi.org/10.22159/ajpcr.2023.v16i3.46284.

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Objective: The aim of the study was to compare the effects of induction agents Propofol and Etomidate on hemodynamic parameters (Heart rate, Systolic Blood Pressure, Diastolic Blood pressure, and mean arterial pressure) in modified electroconvulsive therapy (ECT). Methods: It was a prospective, randomized, and double-blinded study. The present study was conducted in the Department of Anaesthesiology at our tertiary care multispeciality referral hospital, Shri Guru Ram Rai Institute of Medical and Health Sciences, Patel Nagar, Dehradun. A total of 80 adult patients in the age group 20–50 years

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Koshire, Alka Rajesh, Amala Anirudha Godse, Sarita Phulkar, and Hemant Pawar. "Comparison Between Propofol and Etomidate in General Anaesthesia as Induction Agents at a Tertiary Care Centre." MVP Journal of Medical Sciences, April 8, 2022, 179–82. http://dx.doi.org/10.18311/mvpjms/2021/v8i2/318.

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Aims: To compare hemodynamic changes occurring due to Propofol and Etomidate during general anesthesia as induction agents at a Tertiary Care Centre. Materials and Methods: 68 Adult ASA1 and ASA 2 Patients undergoing elective surgeries under gender anaesthesia in the department of Anaesthesia, Medical college and tertiary health care Centre after considering and satisfying the inclusion and exclusion criteria were selected and divided in two equal groups. They were given Propofol (2mg/kg) and Etomidate (0.3mg/kg) and hemodynamics were compared. Results: Etomidate was having more stable hemodyn

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