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Dissertations / Theses on the topic 'Protein fouling'

Author: Grafiati

Published: 4 June 2021

Last updated: 7 September 2024

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1

Alharthi, Majed. "Fouling and cleaning studies of protein fouling at pasteurisation temperatures." Thesis, University of Birmingham, 2014. http://etheses.bham.ac.uk//id/eprint/4892/.

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Fouling and cleaning processes impact industrial production, in terms of economics, product quality, product safety, and plant efficiency. Therefore, optimisation of fouling and cleaning processes is a significant issue, and needs a good understanding of fouling and cleaning kinetics. Ideal monitors should determine the right time when a process run should stop and when a plant will be clean in order to improve the process efficiency. This thesis investigated the fouling and cleaning behaviour of dairy fluids in a plate heat exchanger (PHE) and bench scale fouling rig, using whey protein conce

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2

Gotham, Simon Martyn. "Mechanisms of protein fouling of heat exchangers." Thesis, University of Cambridge, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.357741.

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3

Chan, Robert Chemical Engineering &amp Industrial Chemistry UNSW. "Fouling mechanisms in the membrane filtration of single and binary protein solutions." Awarded by:University of New South Wales. Chemical Engineering and Industrial Chemistry, 2002. http://handle.unsw.edu.au/1959.4/18832.

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In this study the fouling mechanisms of various microfiltration and ultrafiltration membranes were studied when subjected to crossflow filtration using various protein solutions. Experimentation was carried out using controlled flux experiments and fouling phenomena was investigated via the monitoring of the transmembrane pressure (TMP) and rejection. Electron microscopy was employed to study fouling on microfiltration membranes when single protein solutions were filtered while a novel method involving Matrix-Assisted Laser Desorption Ionisation Mass Spectrometry (MALDI-MS) was developed to qu

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4

Huang, Yunqi. "Design and Evaluation of a Laboratory-Scale System for Investigation of Fouling during Thermal Processing Operation." The Ohio State University, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=osu1494245242027853.

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5

Prodan, Bjorg Noah Radu. "Modifying Membrane Surfaces via Self-Assembled Monolayers to Reduce Protein Fouling." University of Cincinnati / OhioLINK, 2004. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1091133289.

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6

RAJAM, SRIDHAR. "TWO SURFACE MODIFICATION METHODS TO REDUCE PROTEIN FOULING IN MICROFILTRATION MEMBRANES." University of Cincinnati / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1172005034.

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7

Rose, Ian C. "Model investigation of initial fouling rates of protein solutions in heat transfer equipment." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape8/PQDD_0026/NQ38965.pdf.

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8

Hamilton-Brown, Paul Optometry &amp Vision Science Faculty of Science UNSW. "A surface forces and protein adsorption study of grafted PEO layers." Awarded by:University of New South Wales. School of Optometry and Vision Science, 2006. http://handle.unsw.edu.au/1959.4/25541.

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A combination of surface analytical techniques, colloid probe Atomic Force Microscopy (AFM) and X-ray Photoelectron Spectroscopy (XPS) was used to optimise the grafting density of covalently attached 5, 20 and 40 kDa methoxy-terminated PEO layers (under marginal solvation (cloud point) conditions for the PEO molecules). The combination of these techniques allowed us to relate the PEO layer density and molecular conformations to the range, magnitude and types of forces generated by coatings of various grafting densities. The key optimisation parameter was the grafting time with the concentratio

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9

Magens, Ole Mathis. "Mitigating fouling of heat exchangers with fluoropolymer coatings." Thesis, University of Cambridge, 2019. https://www.repository.cam.ac.uk/handle/1810/287467.

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Fouling is a chronic problem in many heat transfer systems and results in the need for frequent heat exchanger (HEX) cleaning. In the dairy industry, the associated operating cost and environmental impact are substantial. Antifouling coatings are one mitigation option. In this work, the fouling behaviour of fluoropolymer, polypropylene and stainless steel heat transfer surfaces in processing raw milk and whey protein solution are studied. Methodologies to assess the economics of antifouling coatings are developed and applied. Two experimental apparatuses were designed and constructed to study

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10

Suwal, Shyam, and Shyam Suwal. "Fractionation of Peptides from Protein Hydrolysate by Electrodialysis with Filtration Membrane : process optimization, Fouling characterization and Control mechanisms." Doctoral thesis, Université Laval, 2015. http://hdl.handle.net/20.500.11794/26619.

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Des peptides bioactifs ont déjà été fractionnés par électrodialyse avec membrane de filtration (ÉDMF) à partir d’hydrolysats de sous-produits de crabe des neiges. L’optimisation des paramètres apparaît maintenant indispensable pour perfectionner le procédé. Ainsi, le taux de migration des peptides, leur sélectivité et l'évolution des paramètres électrodialytiques ont été étudiés pour différents paramètres (configuration, concentration en KCl et types de champ électrique). La configuration (2) de la cellule d’ÉDMF comprenant deux compartiments d'alimentation et un compartiment de récupération a

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11

Shen, Mingchao. "Monocyte/macrophage and protein interactions with non-fouling plasma polymerized tetraglyme and chemically modified polystyrene surfaces : in vitro and in vivo studies /." Thesis, Connect to this title online; UW restricted, 2001. http://hdl.handle.net/1773/8013.

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12

Li, Chengcheng. "Etude de l'impact de micropolluants pharmaceutiques sur le colmatage des BAM utilisés en traitement des eaux usées urbaines : cas de la carbamazépine." Thesis, Toulouse, INSA, 2014. http://www.theses.fr/2014ISAT0024/document.

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Le colmatage des membranes reste la principale limitation pour le développement du bioréacteur à membrane (BAM). Dans cette thèse, l'objectif principal se concentre sur les effets des micropolluants pharmaceutiques qui se retrouvent dans les eaux usées domestiques sur le colmatage de la membrane du BAM. Carbamazépine (CBZ), un médicament antiépileptique, a été choisi. Les effets de la CBZ sur le colmatage du BAM ont été étudiés de deux manières: un pic de pollution pour étudier les effets des pics de CBZ à court terme sur le pouvoir colmatant et une pollution continue pour examiner les effets

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13

Zhang, Wenxiang. "Optimization of protein concentration from alfalfa juice by high shear rate dynamic filtration." Thesis, Compiègne, 2016. http://www.theses.fr/2016COMP2281/document.

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Les protéines extraites des feuilles de luzerne sont une source importante de protéines. La filtration membranaire, technologie de séparation respectueuse de l’environnement avec une productivité élevée et de faible coût a été utilisée pour séparer et concentrer les protéines des feuilles de luzerne à partir de leur jus. Cependant le phénomène du colmatage de la membrane qui réduit sérieusement le flux et la séparation des protéines est un facteur limitant important dans l'application de la filtration membranaire. Pour améliorer la récupération des protéines et amenuiser le phénomène du colmat

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14

Srichantra, Arunee. "Studies of UHT-plant fouling by fresh, recombined and reconstituted whole milk : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Food Engineering." Massey University, 2008. http://hdl.handle.net/10179/961.

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The objective of this study was to investigate the effects of preheat treatments on fouling by fresh whole milk (FWM), recombined whole milk (RCB) and reconstituted whole milk (Recon) in the high-temperature heater of indirect UHT plants. Various preheat treatments prior to evaporation during milk powder manufacture were applied to skim milk powder (SMP, 75 °C 2 s, 85 °C, 155 s and 95 °C, 155 s) and whole milk powder (WMP, 95 °C, 33 s). These preheat treatments were so-called “evaporator preheat treatments”. Skim milk powder (SMP) and whole milk powder (WMP) were derived from the same original

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15

Heinemann, Petra Regina. "The problem of fouling in crossflow microfiltration." Thesis, University of Bath, 1987. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.377962.

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16

Chandavarkar, Arun Suresh. "Dynamics of fouling of microporous membranes by proteins." Thesis, Massachusetts Institute of Technology, 1990. http://hdl.handle.net/1721.1/13642.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 1990.<br>Includes bibliographical references (leaves 274-284).<br>by Arun Suresh Chandavarkar.<br>Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 1990.

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17

Snisarenko, Dmytro. "Medium sized molecules clearance through artificial kidneys." Thesis, Toulouse 3, 2016. http://www.theses.fr/2016TOU30270/document.

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Malgré une longue histoire de développement, l'hémodialyse (rein artificiel) possède encore quelques limitations, telles que la perte des propriétés initiales de la membrane en cours de traitement à cause du colmatage et la mauvaise élimination des toxines urémiques de taille moyenne. La présente étude fait partie d'un projet européen nommé BioArt dont le but est d'apporter des solutions à ces limites. Dans cet objectif, l'un des partenaires du projet a proposé le développement d'un nouveau concept de membrane double couche au sein de laquelle sont incorporées des particules adsorbantes. Une c

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18

Daugherty, Melissa J. "REARING TEMPERATURE AFFECTS THE EXPRESSION OF PROTEINS IN THE ADHESIVE OF THE STRIPED ACORN BARNACLE, BALANUS AMPHITRITE." DigitalCommons@CalPoly, 2016. https://digitalcommons.calpoly.edu/theses/1616.

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Barnacles are dominant hard–fouling organisms in marine waters. They attach to substrates by secreting a complex proteinaceous adhesive. Understanding the chemical composition of this multi–protein underwater adhesive and how it is affected by environmental variables, such as oceanic temperatures, is critical for developing nontoxic solutions to control biofouling. Previous experiments in our lab revealed an inverse relationship between critical removal stress (CRS) and temperatures at which barnacles were reared. Further investigations showed that this correlation is not attributed to differe

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19

Liu, Weiji. "Rôle de la micelle de caséine sur la dénaturation thermique des solutions de protéines de lactosérum et les mécanismes d'encrassement." Electronic Thesis or Diss., Université de Lille (2022-....), 2022. http://www.theses.fr/2022ULILR014.

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Le présent travail est une contribution pour mieux comprendre l’influence des micelles de caseine sur l’encrassement de solutions de protéines sériques. En particulier, des approches expérimentales et numériques ont été réalisées, à des tailles laboratoires et pilotes, pour décrire les phénomènes de dénaturation et mieux cerner le rôle du calcium dans les mécanismes d’encrassement. Tout d'abord, l'effet du ratio massique caséine / lactosérum sur les performances d'encrassement des protéines de lactosérum a été étudié dans un échangeur à Plaques à l'échelle pilote. La masse totale du dépôt d'en

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20

Lin, Toung You, and 林東宥. "Study on Protein Fouling in Microfiltration." Thesis, 2000. http://ndltd.ncl.edu.tw/handle/58109992914111381997.

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碩士<br>國立臺灣大學<br>化學工程學研究所<br>88<br>Protein fouling is one of the critical factors governing the performance and overall effectiveness of microfiltration processes. The adsorption and deposition of protein on microfiltration membrane would result in decline of filtration rate and alteration of selectivity of membrane as well. Hence, experiments were performed with bovin serum albumin (BSA) and track-etched polycarbonate (PC) membranes to evaluate how fouling phenomena affects the microfiltration process. The significant flux decline observed in the present work is initiated

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21

Pathak, Mili Vasantkumar. "Fouling of resin in protein a chromatography mechanism, monitoring and control." Thesis, 2017. http://localhost:8080/xmlui/handle/12345678/7399.

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22

Ignagni, Nicholas. "Engineering Applications of Surface Plasmon Resonance: Protein–Protein and Protein–Molecule Interactions." Thesis, 2011. http://hdl.handle.net/10012/6294.

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Protein-protein and protein-molecule interactions are complicated phenomena due to the tendency of proteins to change shape and function in response to their environment. Protein aggregation whether onto surfaces or in solution, can pose numerous problems in industry. Surface plasmon resonance (SPR) devices and quartz crystal microbalances (QCM) are two real-time, label free methods that can be used to detect the interactions between molecules on surfaces. These devices often employ self-assembled monolayers (SAMs) to produce specific surfaces for studying protein-protein interactions. The

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23

Chan, Robert. "Fouling mechanisms in the membrane filtration of single and binary protein solutions /." 2002. http://www.library.unsw.edu.au/~thesis/adt-NUN/public/adt-NUN20030619.092805/index.html.

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24

Gordeev, Ivan. "Příprava tenkých vrstev plazmovou polymerací jako stabilních podložek pro biolékařské aplikace." Doctoral thesis, 2012. http://www.nusl.cz/ntk/nusl-326579.

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Title: Thin films of plasma polymers as stable supports for biomedical applications Author: Ivan Gordeev Institute: Charles University in Prague, Department of Macromolecular Physics Supervisor of the doctoral thesis: Doc. Ing. Andrey Shukurov, Ph.D, Charles University in Prague, Department of Macromolecular Physics. Abstract: Plasma polymers have been widely considered for use as bio-active coatings. In biomedicine, the surfaces that withstand accumulation of biofilms are of particular importance. This thesis is focused on development of new plasma-based methods for deposition of bio-resistan

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25

Rajabzadeh, Amin Reza. "Membrane Fouling During Hollow Fiber Ultrafiltration of Protein Solutions: Computational Fluid Modeling and Physicochemical Properties." Thesis, 2010. http://hdl.handle.net/10012/5786.

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Hollow fiber ultrafiltration is a viable low cost alternative technology for the concentration or separation of protein solutions. However, membrane fouling and solute build up in the vicinity of the membrane surface decrease the performance of the process by lowering the permeate flux. Major efforts have been devoted to study membrane fouling and design more efficient ultrafiltration membrane systems. The complexity of membrane fouling, however, has limited the progress to better understand and predict the occurrence of fouling. This work was motivated by the desire to develop a microscopic C

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26

Li, Pei-Ming, and 李培銘. "A Study on Fouling and Flux Recovery in Filtration of Protein Solution by Inorganic Membrane." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/81024998161981847979.

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碩士<br>淡江大學<br>化學工程與材料工程學系碩士班<br>94<br>In this study, the inorganic tubular membranes(1000, 5000 MWCO) were employed in a cross-flow filtration system to investigate the effect of operation conditions, solutions and membrane properties on protein solutions filtration. The way for cleaning the membrane fouling were also discussed. The solution fluxes and solute rejection were measured under various operating parameters such as membrane MWCO, transmembrane pressure, pH value and solution composition. In addition, in this work also calculate experimental resistance value with resistance-in-series

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27

Xin, Hong. "A study of the mechanisms of chemical cleaning of milk protein fouling deposits using a model material (whey protein concentrate gel)." 2003. http://hdl.handle.net/2292/1928.

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It is crucial to understand the fundamental mechanisms of cleaning milk protein fouling to optimise Cleaning-in-place (CIP) process. Using Whey Protein Concentrate (WPC) gel as a model material and a rapid ultraviolet (UV) spectrophotometry, a comprehensive laboratory study on the cleaning of the WPC gel deposits from hard surface with alkaline cleaning solutions has been conducted. The kinetics of the cleaning process has been established and mathematical models have been developed in order to elucidate the influences of various parameters on cleaning process. This study has provided sound ev

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28

Imam, Tahmina. "SEPARATION OF PROTEINS BY ION EXCHANGE AND MEMBRANE CHROMATOGRAPHY: BUFFER COMPOSITION, INTERFERING IMPURITIES AND FOULING CONSIDERATIONS." 2009. http://hdl.handle.net/1969.1/ETD-TAMU-2009-05-287.

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Efficient separation of target protein from impurities is crucial in bioseparation for large scale production and purity of the target protein. Two separation process approaches were considered in this study. The first approach focused on identifying major impurity and optimization of solution properties for target protein purification. The second approach consisted of designing an adsorbent that interacted specifically with the target molecule. The first study included modification of protein solution properties (pH, ionic strength, buffer ions) in order to maximize lysozyme purification by a

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29

(8986394), Yizhe Zhang. "INTERACTIONS AMONG PROTEINS AND CARBOHYDRATES UNDER THERMAL PROCESSING CONDITIONS AND THEIR EFFECTS ON DAIRY FOULING." Thesis, 2020.

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<p>In dairy processing, dairy ingredients need to be thermally treated to ensure product quality and safety for an extended shelf life. During thermal processes, milk protein denatures and interacts with other dairy ingredients to form a layer of deposit on heated surfaces, known as fouling which can deteriorate process efficiency and product safety. Milk is a complex mixture of proteins, fats, carbohydrates, minerals and vitamins. The heat-sensitive B-lactoglobulin (B-lg) is known to be a key component in fouling formation (constituting 50% of type A fouling deposits) during milk pasteurizati

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30

Skorepova, Jana. "Effect of Electroacidification on Ultrafiltration Performance and Physicochemical Properties of Soy Protein Extracts." Thesis, 2007. http://hdl.handle.net/10012/3474.

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A novel approach for the production of soy protein isolates was investigated integrating electroacidification and membrane ultrafiltration. The effect of electroacidification on the ultrafiltration performance and physicochemical properties of the soy protein extracts was obtained by comparing an electroacidified (pH 6) and a non-electroacidified (pH 9) soy protein extract. The effect of membrane fouling on the permeate flux decline was studied in a hollow fiber and a dead end ultrafiltration system. Due to more significant membrane fouling, the permeate flux was always lower for the electroac

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31

Gandhi, Gagan. "Study of high protein dairy powder (MPC80) susceptibility to fouling and efficacy of micro-nano-bubble aqueous ozone in removal of Bacillus spp. biofilms on stainless steel surfaces." Thesis, 2018. http://hdl.handle.net/2097/38842.

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Master of Science<br>Food Science Institute<br>Jayendra K. Amamcharla<br>Fouling and biofilm formation on stainless-steel (SS) surfaces can be sources for cross-contamination and pose a great threat to the public health and food quality. The dairy industry needs an intervention strategy focusing on technologies discouraging the biofilm attachment and developing a sustainable eco-friendly approach for biofilm removal from the dairy processing surfaces. Since fouling encourages the attachment of bacteria to the SS surfaces, it becomes important to study the ways of reducing the fouling. The bact

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32

Huang, Tsung-Han, and 黃宗涵. "Identification of protein foulant in membrane bioreactor." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/10804258581492725193.

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碩士<br>中原大學<br>土木工程研究所<br>97<br>Development of membrane bioreactors has been limited by problems of membrane fouling, which will decrease the flux but increase the TMP (trans-membrane pressure) and cost for maintenance and operation. Many literature has indicated the major constituent of fouling is extracellular polymeric substances(EPS) which is composed by protein, carbohydrate, humic substances, nucleic acid and lipid. And,the most part of EPS is protein. Recently, many research has aimed at the quantitative analysis of protein in order to find out the relationship between protein and membra

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33

Hsu, Chao-Hsiang, and 許朝翔. "Isothermal Titration Calorimetric Studies of the Non-fouling Interaction Mechanism Between Proteins and Polyethyleneglycol." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/32915936669573110926.

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碩士<br>國立中央大學<br>化學工程與材料工程研究所<br>95<br>The characteristics of preventing nonspecific adsorption of protein has lead to extensive usage of PEG and its derivatives for biomedical applications. We consider that the interaction of water with the PEG is a major determinant of preventing protein adsorption. However, the thermodynamics aspect of the mechanism has not been well addressed. Therefore, in this study, we described the hydration behavior of PEG by measuring the dilution heat of PEG with various salt concentration, types of salt ions, temperature and molecular weight of PEG. In addition, we

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