Academic literature on the topic 'Protein turnover'

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Journal articles on the topic "Protein turnover"

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Ohsumi, Yoshinori. "Protein turnover." IUBMB Life (International Union of Biochemistry and Molecular Biology: Life) 58, no. 5-6 (2006): 363–69. http://dx.doi.org/10.1080/15216540600758539.

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Jackson, A. A. "Protein turnover." European Journal of Clinical Nutrition 63, no. 1 (2009): 153–54. http://dx.doi.org/10.1038/sj.ejcn.1602802.

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Schutz, Yves. "Protein Turnover, Ureagenesis and Gluconeogenesis." International Journal for Vitamin and Nutrition Research 81, no. 23 (2011): 101–7. http://dx.doi.org/10.1024/0300-9831/a000064.

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The major processes discussed below are protein turnover (degradation and synthesis), degradation into urea, or conversion into glucose (gluconeogenesis, Figure 1). Daily protein turnover is a dynamic process characterized by a double flux of amino acids: the amino acids released by endogenous (body) protein breakdown can be reutilized and reconverted to protein synthesis, with very little loss. Daily rates of protein turnover in humans (300 to 400 g per day) are largely in excess of the level of protein intake (50 to 80 g per day). A fast growing rate, as in premature babies or in children re
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Millward, D. J., A. Fereday, N. Gibson, and P. J. Pacy. "Aging, protein requirements, and protein turnover." American Journal of Clinical Nutrition 66, no. 4 (1997): 774–86. http://dx.doi.org/10.1093/ajcn/66.4.774.

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Vincow, Evelyn S., Ruth E. Thomas, Gennifer E. Merrihew, Michael J. MacCoss, and Leo J. Pallanck. "Slowed Protein Turnover in Aging Drosophila Reflects a Shift in Cellular Priorities." Journals of Gerontology: Series A 76, no. 10 (2021): 1734–39. http://dx.doi.org/10.1093/gerona/glab015.

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Abstract The accumulation of protein aggregates and dysfunctional organelles as organisms age has led to the hypothesis that aging involves general breakdown of protein quality control. We tested this hypothesis using a proteomic and informatic approach in the fruit fly Drosophila melanogaster. Turnover of most proteins was markedly slower in old flies. However, ribosomal and proteasomal proteins maintained high turnover rates, suggesting that the observed slowdowns in protein turnover might not be due to a global failure of quality control. As protein turnover reflects the balance of protein
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Manchester, K. L. "Glutamine and protein turnover." Trends in Biochemical Sciences 14, no. 9 (1989): 362–63. http://dx.doi.org/10.1016/0968-0004(89)90007-8.

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Miura, Grant. "Protein turnover: Mitochondrial immaturity." Nature Chemical Biology 10, no. 11 (2014): 877. http://dx.doi.org/10.1038/nchembio.1679.

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Chang, Tsu-Chung, Wei-Yuan Chou, and Gu-Gang Chang. "Protein oxidation and turnover." Journal of Biomedical Science 7, no. 5 (2000): 357–63. http://dx.doi.org/10.1007/bf02255811.

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Tinti, Michele, Maria Lucia S. Güther, Thomas W. M. Crozier, Angus I. Lamond, and Michael A. J. Ferguson. "Proteome turnover in the bloodstream and procyclic forms of Trypanosoma brucei measured by quantitative proteomics." Wellcome Open Research 4 (October 9, 2019): 152. http://dx.doi.org/10.12688/wellcomeopenres.15421.1.

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Background: Cellular proteins vary significantly in both abundance and turnover rates. These parameters depend upon their rates of synthesis and degradation and it is useful to have access to data on protein turnover rates when, for example, designing genetic knock-down experiments or assessing the potential usefulness of covalent enzyme inhibitors. Little is known about the nature and regulation of protein turnover in Trypanosoma brucei, the etiological agent of human and animal African trypanosomiasis. Methods: To establish baseline data on T. brucei proteome turnover, a Stable Isotope Label
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Karademir, Betul, Erdi Sozen, Perinur Bozaykut, et al. "Regulation of protein turnover by heat shock proteins." Free Radical Biology and Medicine 65 (September 2013): S6. http://dx.doi.org/10.1016/j.freeradbiomed.2013.08.116.

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Dissertations / Theses on the topic "Protein turnover"

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Foster, Andrew R. "Growth and protein turnover in fish." Thesis, University of Aberdeen, 1990. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU031828.

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The aims of this thesis were to investigate the effects of the main abiotic and biotic factors on growth and protein turnover in fish. The first experiments were concerned with the effects of seasonal acclimatisation and temperature acclimatisation on tissue-somatic indices, nucleic acid concentrations/ratios and protein synthesis rates in cod. It was concluded that low water temperature resulted in an increase in tissue RNA concentration and reduced RNA (translational) activities. At the same time, protein synthesis rates were similar between cold and warm acclimated fish. Increased tissue RN
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Mulligan, Mark Thomas. "Protein turnover in the isolated mouse diaphragm." Thesis, University of Liverpool, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.328161.

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Parker, Catherine A. L. "Protein turnover in mice selected for appetite." Thesis, University of Edinburgh, 1988. http://hdl.handle.net/1842/19220.

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Heba, Hassaan Mohammad Ali. "Protein turnover in temperate and tropical fish." Thesis, University of Aberdeen, 1992. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU602268.

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The rate of protein growth, synthesis, RNA/protein ratios, RNA activity and protein content in the whole body and specific tissue of five economically important fish species were investigated under a variety of conditions known to affect both the growth and synthesis rate. Theses species were goldfish, tilapia and 3 different species of flatfish plaice, turbot and flounder. In goldfish, water temperature had an effect on both the growth rate and synthesis rate. Cold- acclimated goldfish exhibited higher RNA/protein ratios compared to warm-acclimated goldfish. The warm-acclimated goldfish had h
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McCarthy, Ian Donald. "Feeding behaviour and protein turnover in fish." Thesis, University of Aberdeen, 1993. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU553851.

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Feeding behaviour and growth of rainbow trout, Oncorhynchus mykiss (Walbaum), were found to be influenced by the position of an individual in the group feeding hierarchy. Dominant animals, consuming a greater proportion of the group meal, showed less day-to-day variation in consumption and higher growth rates compared to subordinates. The relationship between consumption, growth and protein synthesis and the influence of protein turnover on individual differences in growth efficiency in rainbow trout were examined. Rates of protein growth and synthesis increased significantly with increasing p
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Schmidt, Michael. "Regulation of protein turnover in fission yeast." [S.l. : s.n.], 2008. http://nbn-resolving.de/urn:nbn:de:bsz:93-opus-36654.

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Kim, Jonghan. "Pharmacokinetics and pharmacodynamics of protein turnover and production in vivo." Connect to this title online, 2004. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1100554543.

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Thesis (Ph. D.)--Ohio State University, 2004.<br>Title from first page of PDF file. Document formatted into pages; contains xxi, 203 p.; also includes graphics. Includes bibliographical references (p. 191-203).
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Crooks, Kim Chantelle. "Turnover of plant plasma membrane proteins." Thesis, Oxford Brookes University, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.363720.

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Yin, Zhikang. "Protein turnover in serum-deprived mammalian cell cultures." Thesis, University of Aberdeen, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.262175.

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The aim of this project is to test the hypothesis that the rate of turnover of newly synthesized proteins plays a major part in the regulation of cell growth. Normal and transformed cells have been used to compare their responses to serum levels. When the cells are cultured in 0.2% serum medium, increase of cell number is slower than in normal cultures. Cell volume is reduced, while cell mass may be maintained or decreased depending on the rate of protein accumulation and cell proliferation, so unbalanced growth may occur in certain circumstances. During serum deprivation, accumulation of newl
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Irvine, Joseph William. "Studies on protein turnover in chicken breast muscle." Thesis, University of Edinburgh, 1988. http://hdl.handle.net/1842/18986.

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Books on the topic "Protein turnover"

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Waterlow, J. C., ed. Protein turnover. CABI, 2006. http://dx.doi.org/10.1079/9780851996134.0000.

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London), Symposium on Protein Turnover (1972. Protein turnover. UMI Research Press, 1989.

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C, Waterlow J., and Waterlow J. C, eds. Protein turnover. CABI Pub., 2006.

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A, Knauf Philip, and Cook John S, eds. Membrane protein biosynthesis and turnover. Academic Press, 1985.

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Maioral, Luis Filipe Rebelo. " Nucleic acid and protein turnover in critically-ill infants". University of Surrey Roehampton, 2000.

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service), ScienceDirect (Online, ed. RNA turnover in bacteria, archaea and organelles. Academic Press/Elsevier, 2008.

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ICOP Meeting (9th 1992 Williamsburg, Va.). Proteolysis and protein turnover: Proceedings of the 9th ICOP Meeting, Williamsburg, Virginia, U.S.A. Edited by Bond J. S and Barrett A. J. Portland Press, 1993.

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Ferreira, R. M. B. The metabolic responses of plants to stress: With particular reference to protein turnover. University of East Anglia, 1987.

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S, Bond J., and Barrett Alan J, eds. Proteolysis and protein turnover: Proceedings of the 9th ICOP Meeting, Williamsburg, Virginia, U.S.A. Portland, 1993.

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Fox, Leora Mestel. Autophagy-linked FYVE protein mediates the turnover of mutant huntingtin and modifies pathogenesis in mouse models of Huntington’s disease. [publisher not identified], 2016.

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Book chapters on the topic "Protein turnover"

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Baker, Julien S., Fergal Grace, Lon Kilgore, et al. "Protein Turnover." In Encyclopedia of Exercise Medicine in Health and Disease. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-540-29807-6_2924.

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Fung, Jia Jun, Karla Blöcher-Juárez, and Anton Khmelinskii. "High-Throughput Analysis of Protein Turnover with Tandem Fluorescent Protein Timers." In Methods in Molecular Biology. Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-1732-8_6.

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AbstractTandem fluorescent protein timers (tFTs) are versatile reporters of protein dynamics. A tFT consists of two fluorescent proteins with different maturation kinetics and provides a ratiometric readout of protein age, which can be exploited to follow intracellular trafficking, inheritance and turnover of tFT-tagged proteins. Here, we detail a protocol for high-throughput analysis of protein turnover with tFTs in yeast using fluorescence measurements of ordered colony arrays. We describe guidelines on optimization of experimental design with regard to the layout of colony arrays, growth conditions, and instrument choice. Combined with semi-automated genetic crossing using synthetic genetic array (SGA) methodology and high-throughput protein tagging with SWAp-Tag (SWAT) libraries, this approach can be used to compare protein turnover across the proteome and to identify regulators of protein turnover genome-wide.
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Welle, Stephen. "Basic Mechanisms of Protein Turnover." In Human Protein Metabolism. Springer New York, 1999. http://dx.doi.org/10.1007/978-1-4612-1458-8_2.

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Reeds, Peter J. "Regulation of Protein Turnover." In Animal Growth Regulation. Springer US, 1989. http://dx.doi.org/10.1007/978-1-4684-8872-2_9.

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Preedy, Victor R., Tahir Siddiq, Elisabeth Cook, Darcey Black, T. Norman Palmer, and Timothy J. Peters. "Alcohol and Protein Turnover." In Alcoholism. Springer US, 1991. http://dx.doi.org/10.1007/978-1-4684-5946-3_26.

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Jensen, K. Birger. "IgM Turnover in Man." In Ciba Foundation Symposium 9 - Protein Turnover. John Wiley & Sons, Ltd., 2008. http://dx.doi.org/10.1002/9780470719923.ch13.

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McFarlane, A. S. "Chairman's Introduction." In Ciba Foundation Symposium 9 - Protein Turnover. John Wiley & Sons, Ltd., 2008. http://dx.doi.org/10.1002/9780470719923.ch1.

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Regoeczi, E., and K. L. Wong. "Effects of Intravenous Neuraminidase on the Turnover of Fibrinogen." In Ciba Foundation Symposium 9 - Protein Turnover. John Wiley & Sons, Ltd., 2008. http://dx.doi.org/10.1002/9780470719923.ch10.

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Takeda, Y., T. R. Parkhill, and M. Nakabayashi. "Generation of125I-Labelled Plasmin in Dogs in Response to Venous Injury." In Ciba Foundation Symposium 9 - Protein Turnover. John Wiley & Sons, Ltd., 2008. http://dx.doi.org/10.1002/9780470719923.ch11.

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Jeejeebhoy, K. N., A. Bruce-Robertson, J. Ho, and U. Sodtke. "The Comparative Effects of Nutritional and Hormonal Factors on the Synthesis of Albumin, Fibrinogen and Transferrin." In Ciba Foundation Symposium 9 - Protein Turnover. John Wiley & Sons, Ltd., 2008. http://dx.doi.org/10.1002/9780470719923.ch12.

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Conference papers on the topic "Protein turnover"

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Filiou, M., C. Guillermier, C. Poczatek, et al. "Paroxetine treatment alters hippocampal protein turnover." In Abstracts of the 30th Symposium of the AGNP. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1606402.

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Somborac, Anita, Marco van der Toorn, Lorenza Franciosi, et al. "Cigarette Smoke Disturbs Protein Turnover Inside Airway Epithelial Cells." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a3539.

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Langen, Ramon, Chiel de Theije, Wout Lamers, Eleonore Koehler, and Annemie M. Schols. "Hypoxia Induces Muscle Atrophy And Increased Muscle Protein Turnover." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a5309.

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Schaefer, Thorsten, Alain Dumlin, Christoph Schürch, et al. "Abstract 4940: Heterogeneous SOX2 protein turnover in human glioblastoma subsets." In Proceedings: AACR Annual Meeting 2020; April 27-28, 2020 and June 22-24, 2020; Philadelphia, PA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.am2020-4940.

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Kneppers, Anita, Ramon Langen, Harry Gosker, et al. "Impaired coordination of skeletal muscle protein turnover signalling in sarcopenic COPD patients." In ERS International Congress 2016 abstracts. European Respiratory Society, 2016. http://dx.doi.org/10.1183/13993003.congress-2016.pa3400.

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Maharjan, P., J. Weil, K. Hilton, et al. "In-vivo intramuscular collagen turnover in Pectoralis major in two broiler strains in relation to woody breast myopathy." In 6th EAAP International Symposium on Energy and Protein Metabolism and Nutrition. Wageningen Academic Publishers, 2019. http://dx.doi.org/10.3920/978-90-8686-891-9_112.

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Dwivedi, Yasha, Michel P. Laurent, Tom Schmid, and Markus A. Wimmer. "Protein State Affects Wear of UHMWPE." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-204577.

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It is well established that the lubricant properties play a key role in the wear of UHMWPE in prosthetic knees [1] and hips [2, 3]. The total protein concentration, the albumin – globulin ratio, the lubricant volume turnover rate, and the protein precipitation rate, all have ben found to affect the polyethylene wear rate [3]. A factor that has not yet been studied, but may be of clinical relevance, is the effect of the state of protein on the wear and friction of prosthetic joints. Protein cleavage is expected in the presence of an inflammatory response [4] and through wear processes at the ar
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Crow, M. J., P. A. Learoyd, R. Warrington, and S. M. Rajah. "PROTEIN C, FIBRINOGEN KINETICS AND PLATELET SURVIVAL IN PATIENTS WITH RECURRENT VENOUS THROMBOSIS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644204.

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Recurrent venous thrombosis though uncommon leads to post phlebitic limb syndrome. The pathogenesis is not readily definable in all cases. We have examined the platelet, coagulation and fibrinolytic systems of a small group of patients with venographically proven recurrent thromboses. Currently 14 patients have been studied. Besides routine investigations all patients had the following: 111 In labelled platelet survival, 125 I fibrinogen kinetics, Protein C (functional and antigenic), a full fibrinolytic screen, antithrombin 111 and plasma B-Tg. With the exception of isotopic studies all inves
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Jankowitz, RC, S. Sreekumar, KM Levine, et al. "Abstract P4-05-02: Differential regulation of ER protein-turnover in invasive lobular carcinoma cells." In Abstracts: 2017 San Antonio Breast Cancer Symposium; December 5-9, 2017; San Antonio, Texas. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.sabcs17-p4-05-02.

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Engelen, Marielle P., Gulnur Com, Yvette C. Luiking, and Nicolaas E. Deutz. "Enhanced De Novo Arginine Synthesis And Protein Turnover In Pediatric Cystic Fibrosis Patients With Nutritional Failure." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a2471.

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Reports on the topic "Protein turnover"

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Buchholz, B. Quantitation of Protein Turnover in the Human Adult Lens Using the 14C Bomb-Pulse. Office of Scientific and Technical Information (OSTI), 2012. http://dx.doi.org/10.2172/1057223.

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Ohad, Itzhak, and Himadri Pakrasi. Role of Cytochrome B559 in Photoinhibition. United States Department of Agriculture, 1995. http://dx.doi.org/10.32747/1995.7613031.bard.

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The aim of this research project was to obtain information on the role of the cytochrome b559 in the function of Photosystem-II (PSII) with special emphasis on the light induced photo inactivation of PSII and turnover of the photochemical reaction center II protein subunit RCII-D1. The major goals of this project were: 1) Isolation and sequencing of the Chlamydomonas chloroplast psbE and psbF genes encoding the cytochrome b559 a and b subunits respectively; 2) Generation of site directed mutants and testing the effect of such mutation on the function of PSII under various light conditions; 3)
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Manulis, Shulamit, Christine D. Smart, Isaac Barash, Guido Sessa, and Harvey C. Hoch. Molecular Interactions of Clavibacter michiganensis subsp. michiganensis with Tomato. United States Department of Agriculture, 2011. http://dx.doi.org/10.32747/2011.7697113.bard.

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Clavibacter michiganensis subsp. michiganensis (Cmm), the causal agent of bacterial wilt and canker of tomato, is the most destructive bacterial disease of tomato causing substantial economic losses in Israel, the U.S.A. and worldwide. The molecular strategies that allow Cmm, a Gram-positive bacterium, to develop a successful infection in tomato plants are largely unknown. The goal of the project was to elucidate the molecular interactions between Cmmand tomato. The first objective was to analyze gene expression profiles of susceptible tomato plants infected with pathogenic and endophytic Cmms
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Hansen, Peter J., Zvi Roth, and Jeremy J. Block. Improving oocyte competence in dairy cows exposed to heat stress. United States Department of Agriculture, 2014. http://dx.doi.org/10.32747/2014.7598163.bard.

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Original Objectives. The overall goal is to develop methods to increase pregnancy rate in lactating dairy cows exposed to heat stress through methods that minimize damage to the oocyte and embryo caused by heat stress. Objectives were as follows: (1) examine the protective effects of melatonin on developmental competence of oocytes exposed to elevated temperature in vitro; (2) test whether melatonin feeding can improve developmental competence of oocytes in vivo and, if so, whether effects are limited to the summer or also occur in the absence of heat stress; and (3) evaluate the effectiveness
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Kannan, Bharadwaj, Roberto B. Pinheiro, and Harry Turtle. A Spanner in the Works: Restricting Labor Mobility and the Inevitable Capital-Labor Substitution. Federal Reserve Bank of Cleveland, 2022. http://dx.doi.org/10.26509/frbc-wp-202230.

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We model an environment with overlapping generations of labor to show that policies restricting labor mobility increase a firm's monopsony power and labor turnover costs. Subsequently, firms increase capital expenditure, altering their optimal capital-labor ratio. We confirm this by exploiting the statewide adoption of the inevitable disclosure doctrine (IDD), a law intended to protect trade secrets by restricting labor mobility. Following an IDD adoption, local firms increase capital expenditure (capital-labor ratio) by 3.5 percent (5.5 percent). This result is magnified for firms with greate
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Huneeus, Cristóbal, Silvia Leiva, and Alejandro Micco. Unemployment Insurance and Search Effort in Chile. Inter-American Development Bank, 2012. http://dx.doi.org/10.18235/0011390.

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Unemployment is a pressing problem in many countries in Latin America. Financial crises and increased globalization increase job turnover and therefore the risk of unemployment. To protect workers, Chile implemented an innovative unemployment insurance (UI) system. UI protects workers but creates moral hazard and self-selection issues. Using administrative data for the period 2007 to 2010, the effect of the 2009 reform of UI on job search behavior was studied. The results revealed different job search behavior between workers who use unemployment benefits and those who do not. Search efforts w
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Kanner, Joseph, Dennis Miller, Ido Bartov, John Kinsella, and Stella Harel. The Effect of Dietary Iron Level on Lipid Peroxidation of Muscle Food. United States Department of Agriculture, 1995. http://dx.doi.org/10.32747/1995.7604282.bard.

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Biological oxidations are almost exclusively metal ion-promoted reactions and in ths respect iron, being the most abundant, is the commonly involved. The effect of dietary iron levels on pork, turkey and chick muscle lipid peroxidation and various other related compounds were evaluated. Crossbred feeder pigs were fed to market weight on corn-soy rations containing either 62, 131 or 209 ppm iron. After slaughter, the muscles were dissected, cooked and stored at 4°C. Heavily fortifying swine rations with iron (&gt;200 ppm) increase nn-heme iron (NHI), thiobarbituric acid reactive substances (TBA
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Einarsson, Rasmus. Nitrogen in the food system. TABLE, 2024. http://dx.doi.org/10.56661/2fa45626.

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Nitrogen (N) plays a dual role in the agri-food system: it is an essential nutrient for all life forms, yet also an environmental pollutant causing a range of environmental and human health impacts. As the plant nutrient needed in greatest quantities, and as a building block of proteins and other biomolecules, N is a necessary part of all life. In the last century, an enormous increase of N turnover in the agri-food system has enabled increasing per-capita food supply for a growing world population, but as an unintended side effect, N pollution has increased to levels widely agreed in science
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