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Dissertations / Theses on the topic 'Protein turnover'

Author: Grafiati

Published: 4 June 2021

Last updated: 15 March 2025

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1

Foster, Andrew R. "Growth and protein turnover in fish." Thesis, University of Aberdeen, 1990. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU031828.

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The aims of this thesis were to investigate the effects of the main abiotic and biotic factors on growth and protein turnover in fish. The first experiments were concerned with the effects of seasonal acclimatisation and temperature acclimatisation on tissue-somatic indices, nucleic acid concentrations/ratios and protein synthesis rates in cod. It was concluded that low water temperature resulted in an increase in tissue RNA concentration and reduced RNA (translational) activities. At the same time, protein synthesis rates were similar between cold and warm acclimated fish. Increased tissue RN

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2

Mulligan, Mark Thomas. "Protein turnover in the isolated mouse diaphragm." Thesis, University of Liverpool, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.328161.

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3

Parker, Catherine A. L. "Protein turnover in mice selected for appetite." Thesis, University of Edinburgh, 1988. http://hdl.handle.net/1842/19220.

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4

Heba, Hassaan Mohammad Ali. "Protein turnover in temperate and tropical fish." Thesis, University of Aberdeen, 1992. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU602268.

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The rate of protein growth, synthesis, RNA/protein ratios, RNA activity and protein content in the whole body and specific tissue of five economically important fish species were investigated under a variety of conditions known to affect both the growth and synthesis rate. Theses species were goldfish, tilapia and 3 different species of flatfish plaice, turbot and flounder. In goldfish, water temperature had an effect on both the growth rate and synthesis rate. Cold- acclimated goldfish exhibited higher RNA/protein ratios compared to warm-acclimated goldfish. The warm-acclimated goldfish had h

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5

McCarthy, Ian Donald. "Feeding behaviour and protein turnover in fish." Thesis, University of Aberdeen, 1993. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU553851.

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Feeding behaviour and growth of rainbow trout, Oncorhynchus mykiss (Walbaum), were found to be influenced by the position of an individual in the group feeding hierarchy. Dominant animals, consuming a greater proportion of the group meal, showed less day-to-day variation in consumption and higher growth rates compared to subordinates. The relationship between consumption, growth and protein synthesis and the influence of protein turnover on individual differences in growth efficiency in rainbow trout were examined. Rates of protein growth and synthesis increased significantly with increasing p

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6

Schmidt, Michael. "Regulation of protein turnover in fission yeast." [S.l. : s.n.], 2008. http://nbn-resolving.de/urn:nbn:de:bsz:93-opus-36654.

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7

Kim, Jonghan. "Pharmacokinetics and pharmacodynamics of protein turnover and production in vivo." Connect to this title online, 2004. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1100554543.

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Thesis (Ph. D.)--Ohio State University, 2004.<br>Title from first page of PDF file. Document formatted into pages; contains xxi, 203 p.; also includes graphics. Includes bibliographical references (p. 191-203).

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8

Crooks, Kim Chantelle. "Turnover of plant plasma membrane proteins." Thesis, Oxford Brookes University, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.363720.

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9

Yin, Zhikang. "Protein turnover in serum-deprived mammalian cell cultures." Thesis, University of Aberdeen, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.262175.

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The aim of this project is to test the hypothesis that the rate of turnover of newly synthesized proteins plays a major part in the regulation of cell growth. Normal and transformed cells have been used to compare their responses to serum levels. When the cells are cultured in 0.2% serum medium, increase of cell number is slower than in normal cultures. Cell volume is reduced, while cell mass may be maintained or decreased depending on the rate of protein accumulation and cell proliferation, so unbalanced growth may occur in certain circumstances. During serum deprivation, accumulation of newl

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10

Irvine, Joseph William. "Studies on protein turnover in chicken breast muscle." Thesis, University of Edinburgh, 1988. http://hdl.handle.net/1842/18986.

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11

Smith, David Michael. "Studies on protein turnover in the perfused rat heart." Thesis, Imperial College London, 1985. http://hdl.handle.net/10044/1/37857.

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12

Vesali, Rokhsareh Farrah. "Amino acid and protein turnover in human skeletal muscle /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-285-3/.

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13

Martin, Niall M. B. "Protein turnover in Salmonids : sexual maturation and hormonal control." Thesis, University of Aberdeen, 1990. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU548688.

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Aspects of tissue protein metabolism were studied in different groups of Atlantic salmon (Salmo salar). Firstly, 2 groups of sea water salmon were fasted for 3 and 5 days, prior to the measurement of tissue fractional rates of protein synthesis (ks, %day), using the method of 3H-phenylalanine flooding. The sensitivity of liver and gill to a short-term fast was indicated by their reduced rates of ks, while in other tissues such as ventricle, stomach and red muscle protein synthesis was unaffected. Both liver and gill are tissues which show the greatest capacities to synthesise protein, expresse

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14

Bartosch, Birke. "The stability and turnover of Xenopus cyclin E." Thesis, University College London (University of London), 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.341884.

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15

Soames, Candida J. "Factor H : a major complement regulatory protein." Thesis, University of Oxford, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.307011.

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16

Lehmann, A. B. "Protein turnover and hormone profiles in old people in health, during an immobilising illness, and in patients suffering from malnutrition." Thesis, University of Newcastle Upon Tyne, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.384015.

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17

Knight, Ashley D. "Is Leucine Intake Associate with Enhanced Muscle Protein Synthesis and Attenuated Muscle Protein Breakdown?" Digital Archive @ GSU, 2013. http://digitalarchive.gsu.edu/nutrition_theses/45.

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Is Supplemental Leucine Intake Associated with Enhanced Post Exercise Muscle Protein Synthesis and Attenuated Muscle Protein Breakdown? Knight AD, Benardot D, Thompson W, and Henes ST Introduction: The role of individual amino acids on protein synthesis and their impact on physical performance is of high importance to athletes and to those studying the science of sports nutrition. Leucine, one of three branched-chain amino acids, is a frequently researched amino acid because of its potential stimulatory effect on muscle protein synthesis (MPS) following exercise in humans. Purpose: Although th

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18

Gowrie, Ian Joseph. "A mew method to estimate whole body protein turnover in man." Thesis, City University London, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.269291.

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19

Palmer, Robert M. "The role of prostaglandins in the hormonal control of protein turnover." Thesis, University of Aberdeen, 1987. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU499302.

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Isolated muscles from the rabbit forelimb synthesised protein at a lower rate than that in the same muscles in vivo; rates of protein degradation were changed only slightly. Insulin stimulated protein synthesis and prostaglandin F2 release in isolated muscles incubated either under a constant tension or with mechanical stretching, having a greater effect on muscles from fasted rabbits. Inhibitors of prostaglandin synthesis, indomethacin and meclofenamate, abolished these effects but had no effect on the controls (-insulin). When added two hours after insulin, indomethacin did not reduce the ho

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20

Puente, Eugenia Rojas. "Turnover and localization of the actin-binding protein Drebrin in neurons." Doctoral thesis, Humboldt-Universität zu Berlin, Lebenswissenschaftliche Fakultät, 2016. http://dx.doi.org/10.18452/17587.

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Die vorliegende Arbeit erforscht die Regulation der Expression von Drebrin; DBN (Developmentally Regulated Brain Protein) in Neuronen. DBN ist ein Protein das Actin bindet und Actin-Filamente bündeln kann. Änderungen der Morphologie der Spines verändern die synaptische Aktivität und Plastizität – wichtigen Prozessen bei der Gedächtnisbildung und Alterung des Gehirns, sowie bei geistigen Störungen bzw. Behinderungen. DBN-Expression im Alter und in einigen neurodegenerativen Krankheiten reduziert ist. Eine schwächere Expression von DBN in Spines geht außerdem mit einem Verlust an synaptischen V

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21

Seymour, Kacie Tinnesz. "Examining the Influence of Muscle Fiber Type on Protein Turnover Signaling in Growing Pigs." Thesis, Virginia Tech, 2020. http://hdl.handle.net/10919/98592.

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Postnatal skeletal muscle growth occurs through myonuclear accretion and high protein turnover rate. While fiber type composition of the muscle could affect protein turnover rate, less is known about how fiber type influences the regulation of protein synthesis and degradation signaling pathways. Thus, the hypothesis of this work was that variation in fiber type composition will differentially affect the regulation of signaling pathways related to protein turnover in skeletal muscle hypertrophy in growing pigs. Downregulated protein synthesis signaling and reduced expression of type II MyHC

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22

Preedy, V. R. "Tissue protein turnover and its modulation by biochemical, nutritional and physiological factors." Thesis, Aston University, 1993. http://publications.aston.ac.uk/21749/.

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23

Rogers, Thomas A. "Long-term biocatalyst performance via heuristic and rigorous modeling approaches." Diss., Georgia Institute of Technology, 2010. http://hdl.handle.net/1853/37194.

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The experiments which are required to directly assess the operational stability of thermostable biocatalysts can be time-consuming, troublesome, and, in the context of industry, expensive. In the present work, we develop and validate two methods for quickly estimating the total turnover number (a useful indicator of lifetime productivity) of a biocatalyst for any desired operating temperature. The first method is a heuristic approach, built upon a complete mathematical derivation from first principles, in which the total turnover number can be calculated from two simple biochemical measureme

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24

Smiles, William J. "Autophagy and Protein Turnover Responses to Exercise-Nutrient Interactions in Human Skeletal Muscle." Thesis, Australian Catholic University, 2017. https://acuresearchbank.acu.edu.au/download/f1a8e479e644b10ac9d30e15f7e1c241ff0d2a095827d32a1b4621fa3fb43abd/3463505/_Smiles__Thesis__ACU_.pdf.

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Skeletal muscle is a dynamic tissue comprising the largest protein reservoir of the human body with a rate of turnover of ~1-2% per day. Protein turnover is regulated by the coordination of intracellular systems regulating protein synthesis and breakdown that converge in a spatiotemporal manner on lysosomal organelles responsible for integrating a variety of contractile and nutritional stimuli. One such system, autophagy, which literally means to ‘self-eat,’ involves capturing of cellular material for deliver to, and disintegration by, the lysosome. The autophagic ‘cargo’ is subsequently recyc

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25

Kratschke, Maximilian Moritz. "Investigating PSD-95 turnover at the synapse using the HaloTag technology." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/31131.

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PSD-95 is an abundant scaffolding protein found in the postsynaptic densities (PSDs) of excitatory synapses throughout the mammalian brain, and plays a critical role in innate and learned behaviours. PSD-95 assembles with numerous other proteins, including glutamate receptors, adhesion molecules and signalling proteins, into postsynaptic supercomplexes that are then organised into nanoclusters that comprise the postsynaptic density of excitatory synapses. While the subcellular localisation of PSD-95 has been widely studied, much less is known about its turnover. In this thesis, I present novel

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26

Clarke, David. "Studies on whole-body nitrogen turnover, protein synthesis and breakdown in man using 15N glycine." Thesis, University of Newcastle Upon Tyne, 1994. http://hdl.handle.net/10443/1666.

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The experimental work described in this thesis was conducted in the surgical research laboratories of Dr Francis D. Moore in the Peter Bent Brigham Hospital (now the Brigham & Women's Hospital) Boston, Massachusetts, USA, between 1978-1979. It formed part of an ongoing programme of research into protein metabolism in man; specifically to measure total body nitrogen turnover and hence protein synthesis and breakdown, initially in normal volunteers receiving various intravenous feeding regimens, and subsequently in patients. The previous year, 1977, had seen the publication of 'Substrate Interac

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27

Collingwood, Karin M. "Ovine calpains and calpastatin : cDNA sequences and mRNA expression during muscle growth." Thesis, University of Nottingham, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.260580.

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28

Zhang, Yaoyang. "Molecular correlates of trait anxiety: expanding biomarker discovery from protein expression to turnover." Diss., lmu, 2010. http://nbn-resolving.de/urn:nbn:de:bvb:19-123628.

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29

López, Ceballos Pablo. "Elucidating how protein turnover in cell-ECM adhesion stabilizes tissue structure during development." Thesis, University of British Columbia, 2016. http://hdl.handle.net/2429/57622.

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Morphogenesis is the process by which cells rearrange to form complex three dimensional structures. Cell to extracellular matrix (ECM) adhesion, primarily mediated by Integrins, is essential for the formation and maintenance of tissue architecture. A critical way to regulate cell-ECM adhesion is by modulating the turnover of Integrins and their adhesion complex, and thereby modulating the stability of Integrin-based adhesions. We previously showed that mechanical force stabilizes Integrin-based adhesions during development by modulating Integrin turnover. Here, we extend our studies to underst

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30

Logan, Heather Elizabeth. "Phosphatidylcholine turnover and protein kinase C in human fibroblasts with mutations affecting peroxisomes." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp05/mq24866.pdf.

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31

Ferreira, R. M. B. "The metabolic responses of plants to stress, with particular reference to protein turnover." Thesis, University of East Anglia, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.376058.

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32

Duggleby, Sarah Louise. "Protein turnover and urea kinetics during pregnancy, maternal body composition and fetal growth." Thesis, University of Southampton, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.302315.

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33

Noble, Brendon Stewart. "Protein turnover in the tissues of fish : the effect of nutrition, exercise and salinity." Thesis, University of Aberdeen, 1989. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=167755.

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The rate of protein synthesis, RNA and protein content in the whole body and specific tissues in 3 economically important fish species was determined under a variety of conditions known to affect the growth rate. In experiment 1, the relationships between protein synthesis in the whole body of juvenile Atlantic cod (<i>Gadus morhua</i>) and ration size and growth rate were identified. The ration induced increases in growth rate were accompanied by linear increases in protein synthesis and RNA/protein ratio in the whole body. In experiment 2, the rate of protein synthesis was measured in the st

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34

Oliver, Susan Claire. "Studies on the turnover, function and secretion of a maize auxin-binding protein (ABP1)." Thesis, University of Kent, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.262476.

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35

Jackson, Starr E. "Influence of dietary amino acid adequacy on performance and muscle protein turnover in poults." Diss., Virginia Polytechnic Institute and State University, 1985. http://hdl.handle.net/10919/54299.

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Several experiments were conducted to identify the limiting amino acids in a 22% corn-soybean meal diet for poults from one to three weeks of age. Additional studies were designed to investigate changes in muscle composition and protein turnover in response to essential (EAA) and nonessential amino acid (NEAA) supplementation of the low protein diet. Developmental changes in muscle metabolism as well as differences between muscles were also examined. Protein synthesis was determined using a ¹⁴C-tyrosine emulsion technique. Protein degradation was calculated as the difference between synthesis

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36

Crompton, Leslie Alan. "Acute nutritional signals in the control of hind-limb protein turnover in lambs in vivo." Thesis, University of Reading, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.281367.

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37

Ganesan, Sundar. "Local protein turnover as a regulatory mechanism of growth and collapse of neuronal growth cones." Doctoral thesis, [S.l.] : [s.n.], 2005. http://deposit.ddb.de/cgi-bin/dokserv?idn=976327376.

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38

Chien, Fan Wui. "A study of maternal and fetal amino acid metabolism and protein turnover during normal pregnancy." Thesis, University of Dundee, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.323646.

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39

Satarug, Soisungwan. "Responses of skeletal muscle protein turnover and amino acid concentration to unloading, denervation and immobilization." Diss., The University of Arizona, 1987. http://hdl.handle.net/10150/184308.

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The effects of denervation, non-weight bearing (unloading) or immobilization on hindlimb muscle growth, protein and amino acid metabolism were studied. In the first 3 days after denervation or unloading, atrophy of the soleus was caused by a suppression of protein synthesis and an acceleration of protein degradation. Thereafter, further atrophy, up to 6 days was due to depressed protein synthesis only. The changes in both protein synthesis and degradation in the first three days accounted for 69% and 65%, respectively, of the total loss of protein and mass in 6 days of unloaded or denervated s

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40

Owen, Stewart Frank. "Protein turnover determined using a stable isotope [Â¹âµN], feeding behaviour and bioenergetics in fish." Thesis, University of Dundee, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.289125.

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41

Lambert, Adrian Joseph. "The effect of ageing and caloric restriction on protein turnover in primary cultures of rat hepatocytes." Thesis, University of Liverpool, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.366239.

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42

Pryor, Anne M. "Growth-regulated expression and G0-specific turnover of the mRNA that encodes AH49, a mammalian protein highly related to the mRNA export protein UAP56." Connect to this title online, 2003. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1069259604.

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Thesis (Ph. D.)--Ohio State University, 2003.<br>Title from first page of PDF file. Document formatted into pages; contains xii, 187 p.; also includes graphics (some col.) Includes bibliographical references (p. 175-187). Available online via OhioLINK's ETD Center

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43

Ali, Shaha. "Effects of salinity and food consumption on growth and protein turnover in Nile tilapia (Oreochromis niloticus Linnaeus)." Thesis, University of Aberdeen, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.367366.

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This thesis examines the effects of salinity, ration level, stocking density and level of protein in diet on food consumption and growth in individual Nile tilapia (<I>Oreochromis niloticus</I> Linnaeus), held in groups and reared under various culture conditions. Nile tilapia reared in different salinities (0, 10 & 20) but fed the same ration level (2% body weight day<sup>-1</sup>), showed no significant differences in growth or white muscle protein concentrations. During feed deprivation, weight loss was similar for fish held on 0 and 10 , but after 7 days over 50% of the fish maintained

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44

Grove, Geraldine. "Variability in the measurement of protein turnover in man using the end product method and '1'5N glycine." Thesis, University of Southampton, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.240627.

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45

Perera, Withanage Mala Kanthimathi. "Growth performance, nitrogen balance and protein turnover of rainbow trout (Oncorhynchus mykiss (Walbaum)) under different dietary regimens." Thesis, University of Aberdeen, 1995. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU068326.

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This thesis presents the results of a series of experiments carried out to determine if bacterial single-cell protein (BSCP) could replace fishmeal in a pelleted diet in rainbow trout (Oncorhynchus mykiss (Walbaum)) and to investigate the quantitative lysine requirement of this species using a methodology for the measurement of individual food consumption rates viz. radiography. In the first investigation, four diets were formulated to contain a total of 45.8% crude protein of which 0% was from BSCP in BSCP-0, 25% in BSCP-25, 62.5% BSCP-62.5 and 100% in BSCP-100; the remainder of the protein b

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46

Kretzschmar, Franziska Kerstin [Verfasser], Till [Akademischer Betreuer] Ischebeck, Till [Gutachter] Ischebeck, and Alexander [Gutachter] Stein. "Protein Turnover on Plant Lipid Droplets / Franziska Kerstin Kretzschmar ; Gutachter: Till Ischebeck, Alexander Stein ; Betreuer: Till Ischebeck." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2020. http://d-nb.info/1209358212/34.

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47

Hamadi, Abdelkader Rondé Philippe. "Rôle de FAK (Focal Adhesion Kinase) dans le turnover des points d'adhérence durant la migration cellulaire." Strasbourg : Université Louis Pasteur, 2008. http://eprints-scd-ulp.u-strasbg.fr:8080/1011/01/HAMADI_Abdelkader3_2008.pdf.

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48

Pfrimer, Karina. "Avaliação do metabolismo protéico em idosos brasileiros independentes utilizando a glicina marcada com 15N." Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/17/17138/tde-17082006-153645/.

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O metabolismo protéico em idosos, analisado pela medida da velocidade de reciclagem, é um importante fator para a análise da manutenção da massa muscular e das atividades de vida diária. Dados coletados em idosos apontam uma redução da síntese protéica com o envelhecimento. Outros relatam ser esta mantida e a degradação aumentada. Esta investigação teve por objetivo avaliar o metabolismo protéico de idosos saudáveis e independentes utilizando a glicina, marcada com o isótopo 15N. Sete idosos saudáveis foram estudados.Foram feitas avaliações clínica, nutricional e bioquímica em todos os voluntá

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49

Spinti, Daniela [Verfasser], Frederik [Akademischer Betreuer] Börnke, Tina [Gutachter] Romeis, and Marcel [Gutachter] Wiermer. "Proteasomal protein turnover during defense priming in Arabidopsis / Daniela Spinti ; Gutachter: Tina Romeis, Marcel Wiermer ; Betreuer: Frederik Börnke." Potsdam : Universität Potsdam, 2021. http://d-nb.info/1235522091/34.

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50

Wu, Min 1958. "In vivo protein turnover and the influence of ecdysteroids in flight muscle of the tobacco hornworm, Manduca sexta." Thesis, The University of Arizona, 1989. http://hdl.handle.net/10150/277242.

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In vivo protein turnover was measured during the last 4 days of flight muscle development in tobacco hornworm pupa. Linear synthesis rates were measured up to 2 hours after injection of 30 μmol (3H) phenylalanine. Since the results with this technique did not differ from another established method, the large bolus injection of phenylalanine did not affect protein synthesis. The former method is advantageous because only a single time point is required. Flight muscle growth and protein synthesis decreased in parallel between 100 and 24 hours. During this time free phenylalanine turnover decreas

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