Log in

Relevant bibliographies by topics / Protein-tyrosine kinase Testis. Rats

Contents

Journal articles
Dissertations / Theses
Books
Book chapters
Conference papers

Academic literature on the topic 'Protein-tyrosine kinase Testis. Rats'

Author: Grafiati

Published: 4 June 2021

Last updated: 6 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Protein-tyrosine kinase Testis. Rats.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Protein-tyrosine kinase Testis. Rats"

1

Zhang, Jiayi, Ching-hang Wong, Weiliang Xia та ін. "Regulation of Sertoli-Germ Cell Adherens Junction Dynamics via Changes in Protein-Protein Interactions of the N-Cadherin-β-Catenin Protein Complex which Are Possibly Mediated by c-Src and Myotubularin-Related Protein 2: An in Vivo Study Using an Androgen Suppression Model". Endocrinology 146, № 3 (2005): 1268–84. http://dx.doi.org/10.1210/en.2004-1194.

Full text

Abstract:

Using a well characterized model of cell-cell actin-based adherens junction (AJ) disruption by suppressing the intratesticular testosterone level in adult rats with testosterone-estradiol implants, we have confirmed earlier findings that Sertoli-germ cell AJ dynamics are regulated by the activation of kinases via putative signaling pathways but with some unexpected findings as follows. First, the loss of germ cells from the seminiferous epithelium during androgen suppression was associated with a surge in myotubularin-related protein 2 (MTMR2, a lipid phosphatase, in which adult MTMR2−/− mice

APA, Harvard, Vancouver, ISO, and other styles

2

Girke, Vera, Josephine Tabea Tauer, Ingmar Glauche, Lorenz Hofbauer, and Meinolf Suttorp. "Impact of Long-Term Tyrosine Kinase Inhibitor Exposure on Spermatogenesis in Juvenile Rats." Blood 128, no. 22 (2016): 1884. http://dx.doi.org/10.1182/blood.v128.22.1884.1884.

Full text

Abstract:

Abstract Background: Pediatric patients with chronic myeloid leukemia (CML) are exposed to off-target side effects from long-term treatment with tyrosine kinase inhibitors (TKIs) which have been observed with increasing watchfulness in the last years (Hijiya N, et al. BLOOD 127:392, 2016). TKIs inhibit c-kit and platelet-derived growth factor receptors (PDGF-R alpha/beta) which are known to regulate spermatogenesis (Zhang M, et al. SCI REP 4:5936, 2014). The influence of TKIs on spermatogenesis in pediatric patients with CML is not fully understood yet (Samis J, et al. PEDIATR BLOOD CANCER 63:

APA, Harvard, Vancouver, ISO, and other styles

3

Tang, Elizabeth I., Will M. Lee, and C. Yan Cheng. "Coordination of Actin- and Microtubule-Based Cytoskeletons Supports Transport of Spermatids and Residual Bodies/Phagosomes During Spermatogenesis in the Rat Testis." Endocrinology 2016, no. 1 (2016): 47–62. http://dx.doi.org/10.1210/en.2015-1962.

Full text

Abstract:

Abstract Germ cell transport across the seminiferous epithelium during spermatogenesis requires the intricate coordination of cell junctions, signaling proteins, and both actin- and microtubule (MT)-based cytoskeletons. Although the involvement of cytoskeletons in germ cell transport has been suggested, the precise mechanism(s) remains elusive. Based on growing evidencethat actin and MT interactions underlie fundamental cellular processes, such as cell motility, it is unlikely that actin- and MT-based cytoskeletons work independently to regulate germ cell transport in the testis. Using rats tr

APA, Harvard, Vancouver, ISO, and other styles

4

Toyoshima, Yuka, Reiko Tokita, Yoichiro Ohne, et al. "Dietary protein deprivation upregulates insulin signaling and inhibits gluconeogenesis in rat liver." Journal of Molecular Endocrinology 45, no. 5 (2010): 329–40. http://dx.doi.org/10.1677/jme-10-0102.

Full text

Abstract:

This study was undertaken to elucidate the effects of dietary protein deprivation on glucose metabolism and hepatic insulin signaling in rats. The results of glucose and pyruvate tolerance tests in rats fed with a 12% casein diet (12C) and a protein-free diet (PF) indicated that protein deprivation enhanced clearance of blood glucose and suppressed gluconeogenesis. Correspondingly, the mRNA level of hepatic phosphoenolpyruvate carboxykinase, a key gluconeogenic enzyme, was suppressed by dietary protein deprivation. In PF-fed rats, total tyrosine phosphorylation of insulin receptor (IR) in the

APA, Harvard, Vancouver, ISO, and other styles

5

El Morsy, EM, and MAE Ahmed. "Protective effects of lycopene on hippocampal neurotoxicity and memory impairment induced by bisphenol A in rats." Human & Experimental Toxicology 39, no. 8 (2020): 1066–78. http://dx.doi.org/10.1177/0960327120909882.

Full text

Abstract:

Bisphenol A (BPA) is used to produce polycarbonate plastic and epoxy resins which are used in many consumer products. Most people encounter BPA in their daily routines. However, it has been heavily reported that BPA has a neurotoxic effect. The present study aimed to investigate the effect of lycopene on cognitive deficits induced by a high dose of BPA focusing on mitogen-activated protein kinase (MAPK)/extracellular signal-regulated kinase (ERK) pathway, oxidative stress, apoptosis, and memory retrieval in adult male rats. Therefore, 72 rats were divided into four groups: control group, BPA g

APA, Harvard, Vancouver, ISO, and other styles

6

Cancilla, B., A. Davies, M. Ford-Perriss, and GP Risbridger. "Discrete cell- and stage-specific localisation of fibroblast growth factors and receptor expression during testis development." Journal of Endocrinology 164, no. 2 (2000): 149–59. http://dx.doi.org/10.1677/joe.0.1640149.

Full text

Abstract:

Fibroblast growth factors (FGFs) are a family of heparin binding proteins involved in many biological processes. These growth factors act through tyrosine kinase receptors (FGFRs); we have previously used immunohistochemistry to study FGFRs-1-4 in foetal, immature and adult rat testes, and found a discrete cell- and stage-specific localisation. Alternative mRNA splicing of FGFRs-1-3 leads to functional variants (IIIb and IIIc) with distinct ligand binding affinities, therefore we have identified the specific expression of functional FGFR variants and the expression and localisation of FGF liga

APA, Harvard, Vancouver, ISO, and other styles

7

Zamoner, Ariane, Kátia Padilha Barreto, Danilo Wilhelm Filho, et al. "Propylthiouracil-induced congenital hypothyroidism upregulates vimentin phosphorylation and depletes antioxidant defenses in immature rat testis." Journal of Molecular Endocrinology 40, no. 3 (2008): 125–35. http://dx.doi.org/10.1677/jme-07-0089.

Full text

Abstract:

Congenital hypothyroidism was induced in rats by adding 0.05% 6-propyl-2-thiouracil in the drinking water from day 9 of gestation, and continually up to postnatal day 15. Structural alterations observed by light microscopy of seminiferous tubules and by transmission electron microscopy of Sertoli cells of treated animals were consistent with hypothyroid condition. Hypothyroidism was also associated with high phospho-p38 mitogen-activated protein kinase and decreased phospho-extracellular signal-regulated kinase 1/2 levels. Furthermore, the phosphorylation and the immunoreactivity of cytoskelet

APA, Harvard, Vancouver, ISO, and other styles

8

Bouraïma-Lelong, Hélène, Marion Vanneste, Christelle Delalande, Leïla Zanatta, Slawomir Wolczynski, and Serge Carreau. "Aromatase gene expression in immature rat Sertoli cells: age-related changes in the FSH signalling pathway." Reproduction, Fertility and Development 22, no. 3 (2010): 508. http://dx.doi.org/10.1071/rd09168.

Full text

Abstract:

Aromatase, the enzyme responsible for the transformation of androgens into oestrogens, is encoded by the cyp19 gene expressed in the testis. The aim of the present study was to analyse the evolution of aromatase gene expression under FSH control in rat Sertoli cells between 10 and 30 days post partum, corresponding to the end of the proliferative period of Sertoli cells, establishment of the blood–testis barrier and acquisition of the mature phenotype. The maximum stimulatory effect of FSH on aromatase gene expression was obtained in 20-day-old rat Sertoli cells, compared with cells from 10- a

APA, Harvard, Vancouver, ISO, and other styles

9

Catizone, A., G. Ricci, J. Del Bravo, and M. Galdieri. "Hepatocyte growth factor modulates in vitro survival and proliferation of germ cells during postnatal testis development." Journal of Endocrinology 189, no. 1 (2006): 137–46. http://dx.doi.org/10.1677/joe.1.06528.

Full text

Abstract:

The hepatocyte growth factor (HGF) is a pleiotropic cytokine that influences mitogenesis, motility and differentiation of many different cell types by its tyrosine kinase receptor c-Met. We previously demonstrated that the c-Met/HGF system is present and functionally active during postnatal testis development. We found also that spermatozoa express c-Met and that HGF has a positive effect on the maintenance of sperm motility. In the present paper, we extend our study on the germ cells at different stages of differentiation during the postnatal development of the testis. We demonstrate that c-m

APA, Harvard, Vancouver, ISO, and other styles

10

Michel, U., J. Esselmann, and E. Nieschlag. "Expression of follistatin messenger ribonucleic acid in Sertoli cell-enriched cultures: regulation by epidermal growth factor and protein kinase C-dependent pathway but not by follicle-stimulating hormone and protein kinase A-dependent pathway." Acta Endocrinologica 129, no. 6 (1993): 525–31. http://dx.doi.org/10.1530/acta.0.1290525.

Full text

Abstract:

In this study the localization and regulation of steady-state follistatin messenger ribonucleic acid (mRNA) levels in testicular cell cultures were examined with a solution-hybridization assay using a specific 32P-labelled cytosolic RNA antisense probe for follistatin and a 35S-labelled cytosolic RNA antisense probe for cyclophilin as internal standard. Testes from immature rats were dispersed with collagenase and fractionated in Sertoli and Leydig cell-enriched cultures. Follistatin mRNA was mainly localized to the Sertoli cell-enriched fraction and the expression of follistatin mRNA could be

APA, Harvard, Vancouver, ISO, and other styles

More sources

Dissertations / Theses on the topic "Protein-tyrosine kinase Testis. Rats"

1

Chan, Chi-wai Michael. "Characterization and regulation of expression of tyrosine kinase receptors rse, axl, mer and their ligand gas6 in the testis /." Hong Kong : University of Hong Kong, 1998. http://sunzi.lib.hku.hk/hkuto/record.jsp?B20357758.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

陳志偉 and Chi-wai Michael Chan. "Characterization and regulation of expression of tyrosine kinase receptors rse, axl, mer and their ligand gas6 in the testis." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1998. http://hub.hku.hk/bib/B31220332.

Full text

APA, Harvard, Vancouver, ISO, and other styles

3

Wong, Chui-shan. "Transcriptional regulation of receptor tyrosine kinases AXL and MER in the testis /." View the Table of Contents & Abstract, 2005. http://sunzi.lib.hku.hk/hkuto/record/B31028081.

Full text

APA, Harvard, Vancouver, ISO, and other styles

4

Wong, Chui-shan, and 黃翠珊. "Transcriptional regulation of receptor tyrosine kinases AXL and MER inthe testis." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2005. http://hub.hku.hk/bib/B45015120.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Li, Chi-hang Jonathan. "Characterization of a sertoli cell product, rat myotubularin : its involvement in cell-cell interactions in the testis /." Hong Kong : University of Hong Kong, 2000. http://sunzi.lib.hku.hk/hkuto/record.jsp?B2198170X.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

李志恆 and Chi-hang Jonathan Li. "Characterization of a sertoli cell product, rat myotubularin: its involvement in cell-cell interactionsin the testis." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2000. http://hub.hku.hk/bib/B31240550.

Full text

APA, Harvard, Vancouver, ISO, and other styles

7

Moraes, Paulo Alexandre de Carvalho. "A participação da proteína cinase mTOR (mammalian target of rapamycin) e do fator transcricional NF-kB na regulação da expressão do GLUT4 em músculo sóleo de ratos." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/42/42137/tde-23052012-092050/.

Full text

Abstract:

A insulina regula a expressão de GLUT4, porém os mecanismos envolvidos nesta regulação não estão definidos. Alguns fatores de transcrição e proteínas cinases estão relacionados com a expressão de GLUT4. Assim, o objetivo desta pesquisa foi investigar a participação dos fatores de transcrição MEF2, HIF-1<font face=\"Symbol\">a e NF-<font face=\"Symbol\">kB, e das proteínas cinases mTOR, PI3K e AKT na regulação da expressão de Slc2a4/GLUT4 induzida pela insulina. Para isso, músculos sóleos de ratos foram incubados por 3 horas em tampão Krebs, tratados ou não com insulina, wortmanina, rapamicina,

APA, Harvard, Vancouver, ISO, and other styles

8

Filho, João Bosco de Oliveira. "Mutação em NRAS causa uma síndrome autoimune linfoproliferativa humana." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/5/5144/tde-04112008-174252/.

Full text

Abstract:

A subfamília p21 RAS de pequenas GTPases, incluindo KRAS, HRAS e NRAS, participa de muitas redes de sinalização, incluindo proliferação celular, organização do citoesqueleto e apoptose, e é o alvo mais freqüente de mutações ativadoras em câncer. Mutações germinativas em KRAS e HRAS causam graves anormalidades desenvolvimentais levando às síndromes de Noonan, cárdio-facial-cutânea e Costello, porem mutações ativadoras germinativas em NRAS não foram descritas até hoje. A síndrome autoimune linfoproliferativa (ALPS) é o mais comum defeito genético de apoptose linfocitária, cursando com autoimunid

APA, Harvard, Vancouver, ISO, and other styles

9

Neto, Antero Gomes. "Modelo experimental de tumor no pulmÃo com implante de cÃlulas tumorais por via intrabrÃnquica: avaliaÃÃo dos efeitos da Talidomida, Gefitinib e Paclitaxel." Universidade Federal do CearÃ, 2006. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=398.

Full text

Abstract:

CoordenaÃÃo de AperfeiÃoamento de Pessoal de NÃvel Superior<br>O cÃncer de pulmÃo tem sido, na Ãltima dÃcada, a principal causa de morte por cÃncer no mundo, apesar do surgimento de novos quimioterÃpicos e das terapias alvo-direcionadas. Por isso, faz-se necessÃrio o entendimento das alteraÃÃes moleculares e biolÃgicas envolvidas nos processos de carcinogÃnese e crescimento tumoral, bem como o desenvolvimento de modelos experimentais adequados que permitam estudar o comportamento biolÃgico dos tumores de pulmÃo e o efeito de drogas antineoplÃsicas. O objetivo desse estudo foi desenvolver um mo

APA, Harvard, Vancouver, ISO, and other styles

10

Zanotto, Camila Ziliotto. "Papel da O-glicosilação com N-acetil-glucosamina (O-GlcNAc) no influxo e recaptação de cálcio pelo retículo sarcoplasmático em aorta de ratos: análise funcional." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/17/17133/tde-09092013-133940/.

Full text

Abstract:

A O-glicosilação com N-acetil-glucosamina (O-GlcNAc) é uma modificação pós-translacional altamente dinâmica que modula diversas vias de sinalização. O processo de O-GlcNAc é controlado por duas enzimas: a enzima OGT é responsável por catalisar a adição de N-acetil-glucosamina no grupo hidroxila dos resíduos de serina e treonina, enquanto a OGA catalisa a remoção de O-GlcNAc das proteínas modificadas. Proteínas com importante papel na função vascular são alvo de O-GlcNAc e o aumento da expressão de proteínas modificadas por O-GlcNAc promove aumento da reatividade vascular para estímulos contrát

APA, Harvard, Vancouver, ISO, and other styles

More sources

Books on the topic "Protein-tyrosine kinase Testis. Rats"

1

Nikula, Hannu. Endocrine and paracrine modulation of gonadotropin action in the rat testis. Turun Yliopisto, 1990.

Find full text

APA, Harvard, Vancouver, ISO, and other styles

2

Reddy, Ugan, and Nicholas Hirsch. Diagnosis, assessment, and management of myasthenia gravis and paramyasthenic syndromes. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0244.

Full text

Abstract:

Diseases that affect the neuromuscular junction (NMJ) interfere with normal nerve transmission and cause weakness of voluntary muscles. The two most commonly encountered are acquired myasthenia gravis (MG) and the Lambert–Eaton myasthenic syndrome (LEMS). Acquired MG is an autoimmune disease in which antibodies are directed towards receptors at the NMJ. In 85% of patients, IgG antibodies against the postsynaptic acetylcholine receptor (AChR) are found (seropositive MG). The thymus gland appears to be involved in the production of these which cause an increase rate of degradation of AChR result

APA, Harvard, Vancouver, ISO, and other styles

Book chapters on the topic "Protein-tyrosine kinase Testis. Rats"

1

Sudiyani, Yanni, Muhammad Eka Prastya, Roni Maryana, Eka Triwahyuni, and Muryanto. "The Budding Yeast Saccharomyces cerevisiae as a Valuable Model Organism for Investigating Anti-Aging Compounds." In Saccharomyces. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.96662.

Full text

Abstract:

Saccharomyces cerevisiae, the budding yeast was long history as industrial baker’s yeast due to its ability to produce numerous product such as ethanol, acetate, industrial bakers etc. Interestingly, this yeast was also important tools for studying biological mechanism in eukaryotic cells including aging, autophagy, mitochondrial response etc. S. cerevisiae has arisen as a powerful chemical and genetic screening platform, due to a rapid workflow with experimental amenability and the availability of a wide range of genetic mutant libraries. Calorie restriction (CR) as the reduction of nutrients intake could promote yeast longevity through some pathways such as inhibition of nutrient sensing target of rapamycin (TOR), serine–threonine kinase (SCH9), protein adenylate cyclase (AC), protein kinase A (PKA) and ras, reduced ethanol, acetic acid and apoptotic process. In addition, CR also induces the expression of antioxidative proteins, sirtuin2 (Sir2), autophagy and induction of mitochondrial yeast adaptive response. Three methods, spotting test; chronological life span (CLS) and replicative life span (RLS) assays, have been developed to study aging in S. cerevisiae. Here, we present strategies for pharmacological anti-aging screens in yeast, discuss common pitfalls and summarize studies that have used yeast for drug discovery.

APA, Harvard, Vancouver, ISO, and other styles

Conference papers on the topic "Protein-tyrosine kinase Testis. Rats"

1

Kienast, J., J. Arnout, G. Pfliegler, H. Deckmyn, B. Hoet, and J. Vermylen. "DISSOCIATION OF PHOSPHOLIPASE A2 ACTIVATION FROM CYTOSOLIC FREE CA2+ MOBILIZATION IN PLATELETS EXPOSED TO FLUORIDE." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644529.

Full text

Abstract:

Elevated cytosolic free Ca2+ concentrations ([Ca2+]i) are thought to be required for phosphol ipase A2 activity to liberate arachidonic acid (AA) from membrane phospholipids in platelets. The major AA metabolite formed during agonist-induced platelet activation is thromboxane A2 (TxA2). We have investigated the effect of sodium fluoride (NaF) on platelet TxAz formation in correlation to platelet functional changes (aggregation and release of ATP) and intracellular events specific for either agonist- or antagonist-induced platelet responses. A first peak in platelet TxAffi formation reaching 30

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!