Log in

Relevant bibliographies by topics / Proteomics approaches / Journal articles

To see the other types of publications on this topic, follow the link: Proteomics approaches.

Journal articles on the topic 'Proteomics approaches'

Author: Grafiati

Published: 6 September 2023

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Proteomics approaches.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

DePalma, Angelo. "Improving Proteomics Approaches." Genetic Engineering & Biotechnology News 33, no. 10 (2013): 24–26. http://dx.doi.org/10.1089/gen.33.10.10.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Kalvodova, Lucie. "Understanding the proteomes using non-proteomics approaches: Expanding the scope of PROTEOMICS." PROTEOMICS 17, no. 1-2 (2017): 1770013. http://dx.doi.org/10.1002/pmic.201770013.

Full text

APA, Harvard, Vancouver, ISO, and other styles

3

Mahajan, R., and P. Gupta. "Proteomics: taking over where genomics leaves off." Czech Journal of Genetics and Plant Breeding 46, No. 2 (2010): 47–53. http://dx.doi.org/10.17221/34/2009-cjgpb.

Full text

Abstract:

The proteomic studies are simultaneously developed in several directions and significantly influence our notions on the capabilities of biological sciences. The need for proteomics research is necessary as there are certain genes in a cell that encode proteins with specific functions. Using a variety of techniques, proteomics can be used to study how proteins interact within a system or how the protein expression changes in different parts of the body, in different stages of its life cycle and in different environmental conditions as every individual has one genome and many proteomes. Besides

APA, Harvard, Vancouver, ISO, and other styles

4

Sokolowska, Izabela, Armand G. Ngounou Wetie, Alisa G. Woods, and Costel C. Darie. "Applications of Mass Spectrometry in Proteomics." Australian Journal of Chemistry 66, no. 7 (2013): 721. http://dx.doi.org/10.1071/ch13137.

Full text

Abstract:

Characterisation of proteins and whole proteomes can provide a foundation to our understanding of physiological and pathological states and biological diseases or disorders. Constant development of more reliable and accurate mass spectrometry (MS) instruments and techniques has allowed for better identification and quantification of the thousands of proteins involved in basic physiological processes. Therefore, MS-based proteomics has been widely applied to the analysis of biological samples and has greatly contributed to our understanding of protein functions, interactions, and dynamics, adva

APA, Harvard, Vancouver, ISO, and other styles

5

Roeraade, Johan. "Nanotechnology Approaches to Proteomics." Biochemical Society Transactions 27, no. 3 (1999): A69. http://dx.doi.org/10.1042/bst027a069a.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Vahkal, Brett, Jamie Kraft, Emanuela Ferretti, Minyoung Chung, Jean-François Beaulieu, and Illimar Altosaar. "Review of Methodological Approaches to Human Milk Small Extracellular Vesicle Proteomics." Biomolecules 11, no. 6 (2021): 833. http://dx.doi.org/10.3390/biom11060833.

Full text

Abstract:

Proteomics can map extracellular vesicles (EVs), including exosomes, across disease states between organisms and cell types. Due to the diverse origin and cargo of EVs, tailoring methodological and analytical techniques can support the reproducibility of results. Proteomics scans are sensitive to in-sample contaminants, which can be retained during EV isolation procedures. Contaminants can also arise from the biological origin of exosomes, such as the lipid-rich environment in human milk. Human milk (HM) EVs and exosomes are emerging as a research interest in health and disease, though the exp

APA, Harvard, Vancouver, ISO, and other styles

7

Oikonomou, Panos, Roberto Salatino, and Saeed Tavazoie. "In vivo mRNA display enables large-scale proteomics by next generation sequencing." Proceedings of the National Academy of Sciences 117, no. 43 (2020): 26710–18. http://dx.doi.org/10.1073/pnas.2002650117.

Full text

Abstract:

Large-scale proteomic methods are essential for the functional characterization of proteins in their native cellular context. However, proteomics has lagged far behind genomic approaches in scalability, standardization, and cost. Here, we introduce in vivo mRNA display, a technology that converts a variety of proteomics applications into a DNA sequencing problem. In vivo-expressed proteins are coupled with their encoding messenger RNAs (mRNAs) via a high-affinity stem-loop RNA binding domain interaction, enabling high-throughput identification of proteins with high sensitivity and specificity

APA, Harvard, Vancouver, ISO, and other styles

8

FOSTER, LEONARD J. "MASS SPECTROMETRY OUTGROWS SIMPLE BIOCHEMISTRY: NEW APPROACHES TO ORGANELLE PROTEOMICS." Biophysical Reviews and Letters 01, no. 02 (2006): 209–21. http://dx.doi.org/10.1142/s1793048006000057.

Full text

Abstract:

Organelles are subcellular compartments or structures that typically carry out a defined set of functions within the cell. The functions of many organelles are known or predicted, but without knowing all the components of any recognized organelle it is difficult to fully understand them. Mass spectrometry-based proteomics now allows for routine identification of several hundreds or thousands of proteins in very complex samples; for cell biologists, organelles represent perhaps the most interesting class of cellular components to apply this new technology to. However, in order to analyze the pr

APA, Harvard, Vancouver, ISO, and other styles

9

Pino, Lindsay K., Jacob Rose, Amy O'Broin, Samah Shah, and Birgit Schilling. "Emerging mass spectrometry-based proteomics methodologies for novel biomedical applications." Biochemical Society Transactions 48, no. 5 (2020): 1953–66. http://dx.doi.org/10.1042/bst20191091.

Full text

Abstract:

Research into the basic biology of human health and disease, as well as translational human research and clinical applications, all benefit from the growing accessibility and versatility of mass spectrometry (MS)-based proteomics. Although once limited in throughput and sensitivity, proteomic studies have quickly grown in scope and scale over the last decade due to significant advances in instrumentation, computational approaches, and bio-sample preparation. Here, we review these latest developments in MS and highlight how these techniques are used to study the mechanisms, diagnosis, and treat

APA, Harvard, Vancouver, ISO, and other styles

10

Gnatenko, Dmitri V., Peter L. Perrotta, and Wadie F. Bahou. "Proteomic approaches to dissect platelet function: half the story." Blood 108, no. 13 (2006): 3983–91. http://dx.doi.org/10.1182/blood-2006-06-026518.

Full text

Abstract:

AbstractPlatelets play critical roles in diverse hemostatic and pathologic disorders and are broadly implicated in various biological processes that include inflammation, wound healing, and thrombosis. Recent progress in high-throughput mRNA and protein profiling techniques has advanced our understanding of the biological functions of platelets. Platelet proteomics has been adopted to decode the complex processes that underlie platelet function by identifying novel platelet-expressed proteins, dissecting mechanisms of signal or metabolic pathways, and analyzing functional changes of the platel

APA, Harvard, Vancouver, ISO, and other styles

11

Fung, Eric T., Scot R. Weinberger, Ed Gavin, and Fujun Zhang. "Bioinformatics approaches in clinical proteomics." Expert Review of Proteomics 2, no. 6 (2005): 847–62. http://dx.doi.org/10.1586/14789450.2.6.847.

Full text

APA, Harvard, Vancouver, ISO, and other styles

12

Liu, Brian CS, and Joshua R. Ehrlich. "Proteomics approaches to urologic diseases." Expert Review of Proteomics 3, no. 3 (2006): 283–96. http://dx.doi.org/10.1586/14789450.3.3.283.

Full text

APA, Harvard, Vancouver, ISO, and other styles

13

Manadas, Bruno, Vera M. Mendes, Jane English, and Michael J. Dunn. "Peptide fractionation in proteomics approaches." Expert Review of Proteomics 7, no. 5 (2010): 655–63. http://dx.doi.org/10.1586/epr.10.46.

Full text

APA, Harvard, Vancouver, ISO, and other styles

14

Zhou, M. "Proteomics approaches to biomarker detection." Briefings in Functional Genomics and Proteomics 4, no. 1 (2005): 69–75. http://dx.doi.org/10.1093/bfgp/4.1.69.

Full text

APA, Harvard, Vancouver, ISO, and other styles

15

Thompson, D. C. "15 Methodological approaches in proteomics." Toxicology Letters 144 (September 2003): s4. http://dx.doi.org/10.1016/s0378-4274(03)90014-2.

Full text

APA, Harvard, Vancouver, ISO, and other styles

16

Sharma, Vipin Kumar, and Ravi Kumar. "Current applications of proteomics: a key and novel approach." International Journal of Advances in Medicine 6, no. 6 (2019): 1953. http://dx.doi.org/10.18203/2349-3933.ijam20195259.

Full text

Abstract:

Proteomics represented vital applications of technologies in the identification and quantification of high to moderate proteins (cellular signalling networks) found in biological matrix such as tissues, cells and fluids. Proteomics based technical knowledge is applied and verified in several preclinical research settings such as invention of diagnostic markers for specific disease and have shown to be increased in clinical applications. Extensive studies on proteomics resulted in detection of biomarkers that have been highly advanced in using diseases for cancer, lungs, cardiovascular, renal a

APA, Harvard, Vancouver, ISO, and other styles

17

Kalaiselvi, B., and M. Thangamani. "Computational Approaches for Understanding High Quality Mass Spectrometry Proteomic Data." Journal of Computational and Theoretical Nanoscience 16, no. 2 (2019): 516–20. http://dx.doi.org/10.1166/jctn.2019.7761.

Full text

Abstract:

Computational approach of proteomic data science is used to identification and quantification of protein and provides the high-throughput data, concentration changes, interactions, posttranslational modifications and cellular localizations. The high-quality mass spectrometry recall to understanding the different sources of unsigned high-quality spectra features. The iterative computational method is interrogating the high efficiency of mass spectrometry protein data. The approach contains several databases searching with different search parameters, spectral library searching, modified peptide

APA, Harvard, Vancouver, ISO, and other styles

18

Rodríguez-Ulloa, Arielis, Jeovanis Gil, Yassel Ramos, et al. "Proteomic Study to Survey the CIGB-552 Antitumor Effect." BioMed Research International 2015 (2015): 1–18. http://dx.doi.org/10.1155/2015/124082.

Full text

Abstract:

CIGB-552 is a cell-penetrating peptide that exertsin vitroandin vivoantitumor effect on cancer cells. In the present work, the mechanism involved in such anticancer activity was studied using chemical proteomics and expression-based proteomics in culture cancer cell lines. CIGB-552 interacts with at least 55 proteins, as determined by chemical proteomics. A temporal differential proteomics based on iTRAQ quantification method was performed to identify CIGB-552 modulated proteins. The proteomic profile includes 72 differentially expressed proteins in response to CIGB-552 treatment. Proteins rel

APA, Harvard, Vancouver, ISO, and other styles

19

Cutillas, Pedro, Alma Burlingame, and Robert Unwin. "Proteomic Strategies and Their Application in Studies of Renal Function." Physiology 19, no. 3 (2004): 114–19. http://dx.doi.org/10.1152/nips.01515.2003.

Full text

Abstract:

Proteomics is a promising new tool for functional genomics. In addition to two-dimensional gel electrophoresis, other methods that are based on liquid chromatography and mass spectrometry are now available to study proteins. In this brief article, we review the strengths and limitations of the proteomic approaches currently available to the researcher, and we provide examples of how proteomics has been, and can in the future be, used to study the kidney.

APA, Harvard, Vancouver, ISO, and other styles

20

Abdallah, Cosette, Eliane Dumas-Gaudot, Jenny Renaut, and Kjell Sergeant. "Gel-Based and Gel-Free Quantitative Proteomics Approaches at a Glance." International Journal of Plant Genomics 2012 (November 20, 2012): 1–17. http://dx.doi.org/10.1155/2012/494572.

Full text

Abstract:

Two-dimensional gel electrophoresis (2-DE) is widely applied and remains the method of choice in proteomics; however, pervasive 2-DE-related concerns undermine its prospects as a dominant separation technique in proteome research. Consequently, the state-of-the-art shotgun techniques are slowly taking over and utilising the rapid expansion and advancement of mass spectrometry (MS) to provide a new toolbox of gel-free quantitative techniques. When coupled to MS, the shotgun proteomic pipeline can fuel new routes in sensitive and high-throughput profiling of proteins, leading to a high accuracy

APA, Harvard, Vancouver, ISO, and other styles

21

Bespyatykh, Ju A., E. A. Shitikov, and E. N. Ilina. "Proteomics for the Investigation of Mycobacteria." Acta Naturae 9, no. 1 (2017): 15–25. http://dx.doi.org/10.32607/20758251-2017-9-1-15-25.

Full text

Abstract:

The physiology of Mycobacterium tuberculosis, the causative agent of tuberculosis, is being studied with intensity. However, despite the genomic and transcriptomic data available today, the pathogenic potential of these bacteria remains poorly understood. Therefore, proteomic approaches seem relevant in studying mycobacteria. This review covers the main stages in the proteomic analysis methods used to study mycobacteria. The main achievements in the area of M. tuberculosis proteomics are described in general. Special attention is paid to the proteomic features of the Beijing family, which is w

APA, Harvard, Vancouver, ISO, and other styles

22

Mirza, Shama P., and Michael Olivier. "Methods and approaches for the comprehensive characterization and quantification of cellular proteomes using mass spectrometry." Physiological Genomics 33, no. 1 (2008): 3–11. http://dx.doi.org/10.1152/physiolgenomics.00292.2007.

Full text

Abstract:

Proteomics has been proposed as one of the key technologies in the postgenomic era. So far, however, the comprehensive analysis of cellular proteomes has been a challenge because of the dynamic nature and complexity of the multitude of proteins in cells and tissues. Various approaches have been established for the analyses of proteins in a cell at a given state, and mass spectrometry (MS) has proven to be an efficient and versatile tool. MS-based proteomics approaches have significantly improved beyond the initial identification of proteins to comprehensive characterization and quantification

APA, Harvard, Vancouver, ISO, and other styles

23

Tracz, Joanna, and Magdalena Luczak. "Applying Proteomics and Integrative “Omics” Strategies to Decipher the Chronic Kidney Disease-Related Atherosclerosis." International Journal of Molecular Sciences 22, no. 14 (2021): 7492. http://dx.doi.org/10.3390/ijms22147492.

Full text

Abstract:

Patients with chronic kidney disease (CKD) are at increased risk of atherosclerosis and premature mortality, mainly due to cardiovascular events. However, well-known risk factors, which promote “classical” atherosclerosis are alone insufficient to explain the high prevalence of atherosclerosis-related to CKD (CKD-A). The complexity of the molecular mechanisms underlying the acceleration of CKD-A is still to be defied. To obtain a holistic picture of these changes, comprehensive proteomic approaches have been developed including global protein profiling followed by functional bioinformatics ana

APA, Harvard, Vancouver, ISO, and other styles

24

Kondo, Tadashi, Daisuke Kubota, and Akira Kawai. "Application of Proteomics to Soft Tissue Sarcomas." International Journal of Proteomics 2012 (June 19, 2012): 1–15. http://dx.doi.org/10.1155/2012/876401.

Full text

Abstract:

Soft tissue sarcomas are rare and account for less than 1% of all malignant cancers. Other than development of intensive therapies, the clinical outcome of patients with soft tissue sarcoma remains very poor, particularly when diagnosed at a late stage. Unique mutations have been associated with certain soft tissue sarcomas, but their etiologies remain unknown. The proteome is a functional translation of a genome, which directly regulates the malignant features of tumors. Thus, proteomics is a promising approach for investigating soft tissue sarcomas. Various proteomic approaches and clinical

APA, Harvard, Vancouver, ISO, and other styles

25

He, Fuchu. "Microbial Proteomics: Approaches, Advances, and Applications." Journal of Bioinformatics and Proteomics Review 2, no. 2 (2016): 1–7. http://dx.doi.org/10.15436/2381-0793.16.004.

Full text

APA, Harvard, Vancouver, ISO, and other styles

26

CLANCY, OLIVIA, and JENNY E. MYERS. "PROTEOMICS APPROACHES IN PRE-ECLAMPSIA RESEARCH." Fetal and Maternal Medicine Review 20, no. 2 (2009): 143–60. http://dx.doi.org/10.1017/s0965539509002319.

Full text

Abstract:

Much of our current understanding of human gestation is largely based on information extracted from animal and cell models. Although this information has been fundamental for progression of reproductive research, much of it examines biological molecules in isolation rather than the integrated manner in which they function. Disruption to these fundamental processes is the source of pregnancy complications, of which for many (including pre-eclampsia) the exact aetiology has not been fully elucidated. We need to re-examine the limited way by which we approach these problems, and aim to understand

APA, Harvard, Vancouver, ISO, and other styles

27

Liu, Brian C., Shuzhen Qin, Cindy Williams, and Michael P. O'Leary. "306: Proteomics Approaches to Interstitial Cystitis." Journal of Urology 173, no. 4S (2005): 84–85. http://dx.doi.org/10.1016/s0022-5347(18)34571-3.

Full text

APA, Harvard, Vancouver, ISO, and other styles

28

Schulenborg, T., O. Schmidt, A. van Hall, H. E. Meyer, M. Hamacher, and K. Marcus. "Proteomics in neurodegeneration – disease driven approaches." Journal of Neural Transmission 113, no. 8 (2006): 1055–73. http://dx.doi.org/10.1007/s00702-006-0512-8.

Full text

APA, Harvard, Vancouver, ISO, and other styles

29

Yan, Guokai, and Xianghua Yan. "Ribosomal proteomics: Strategies, approaches, and perspectives." Biochimie 113 (June 2015): 69–77. http://dx.doi.org/10.1016/j.biochi.2015.03.024.

Full text

APA, Harvard, Vancouver, ISO, and other styles

30

Gajahin Gamage, Nadeeka Thushari, Rina Miyashita, Kazutaka Takahashi, Shuichi Asakawa, and Jayan Duminda Mahesh Senevirathna. "Proteomic Applications in Aquatic Environment Studies." Proteomes 10, no. 3 (2022): 32. http://dx.doi.org/10.3390/proteomes10030032.

Full text

Abstract:

Genome determines the unique individualities of organisms; however, proteins play significant roles in the generation of the colorful life forms below water. Aquatic systems are usually complex and multifaceted and can take on unique modifications and adaptations to environmental changes by altering proteins at the cellular level. Proteomics is an essential strategy for exploring aquatic ecosystems due to the diverse involvement of proteins, proteoforms, and their complexity in basic and advanced cellular functions. Proteomics can expedite the analysis of molecular mechanisms underlying biolog

APA, Harvard, Vancouver, ISO, and other styles

31

Steele, Joel R., Carly J. Italiano, Connor R. Phillips, et al. "Misincorporation Proteomics Technologies: A Review." Proteomes 9, no. 1 (2021): 2. http://dx.doi.org/10.3390/proteomes9010002.

Full text

Abstract:

Proteinopathies are diseases caused by factors that affect proteoform conformation. As such, a prevalent hypothesis is that the misincorporation of noncanonical amino acids into a proteoform results in detrimental structures. However, this hypothesis is missing proteomic evidence, specifically the detection of a noncanonical amino acid in a peptide sequence. This review aims to outline the current state of technology that can be used to investigate mistranslations and misincorporations whilst framing the pursuit as Misincorporation Proteomics (MiP). The current availability of technologies exp

APA, Harvard, Vancouver, ISO, and other styles

32

Bowman, John P. "Proteomic applications in microbial identification." Microbiology Australia 32, no. 2 (2011): 77. http://dx.doi.org/10.1071/ma11077.

Full text

Abstract:

Proteomics-based approaches have been used in microbial taxonomy for the last several decades. Recent improvements in instruments and software have led to the appearance of mass spectrometric fingerprinting and peptide survey approaches allowing for highly rapid and accurate taxonomic diagnoses suitable for high-throughput laboratories as well as means to deeply analyse entire proteomes.

APA, Harvard, Vancouver, ISO, and other styles

33

Monti, Maria, Stefania Orrù, Daniela Pagnozzi, and Piero Pucci. "Interaction Proteomics." Bioscience Reports 25, no. 1-2 (2005): 45–56. http://dx.doi.org/10.1007/s10540-005-2847-z.

Full text

Abstract:

The term proteome is traditionally associated with the identification of a large number of proteins within complex mixtures originating from a given organelle, cell or even organism. Current proteome investigations are basically focused on two major areas, expression proteomics and functional proteomics. Both approaches rely on the fractionation of protein mixtures essentially by two-dimensional polyacrylamide gel electrophoresis (2D-gel) and the identification of individual protein bands by mass spectrometric techniques (2D-MS). Functional proteomics approaches are basically addressing two ma

APA, Harvard, Vancouver, ISO, and other styles

34

Nichols, Heather L., Ning Zhang, and Xuejun Wen. "Proteomics and genomics of microgravity." Physiological Genomics 26, no. 3 (2006): 163–71. http://dx.doi.org/10.1152/physiolgenomics.00323.2005.

Full text

Abstract:

Many serious adverse physiological changes occur during spaceflight. In the search for underlying mechanisms and possible new countermeasures, many experimental tools and methods have been developed to study microgravity caused physiological changes, ranging from in vitro bioreactor studies to spaceflight investigations. Recently, genomic and proteomic approaches have gained a lot of attention; after major scientific breakthroughs in the fields of genomics and proteomics, they are now widely accepted and used to understand biological processes. Understanding gene and/or protein expression is t

APA, Harvard, Vancouver, ISO, and other styles

35

Poetsch, Ansgar, and María Inés Marchesini. "Proteomics of Brucella." Proteomes 8, no. 2 (2020): 8. http://dx.doi.org/10.3390/proteomes8020008.

Full text

Abstract:

Brucella spp. are Gram negative intracellular bacteria responsible for brucellosis, a worldwide distributed zoonosis. A prominent aspect of the Brucella life cycle is its ability to invade, survive and multiply within host cells. Comprehensive approaches, such as proteomics, have aided in unravelling the molecular mechanisms underlying Brucella pathogenesis. Technological and methodological advancements such as increased instrument performance and multiplexed quantification have broadened the range of proteome studies, enabling new and improved analyses, providing deeper and more accurate prot

APA, Harvard, Vancouver, ISO, and other styles

36

Eligini, Sonia, Erica Gianazza, Alice Mallia, Stefania Ghilardi, and Cristina Banfi. "Macrophage Phenotyping in Atherosclerosis by Proteomics." International Journal of Molecular Sciences 24, no. 3 (2023): 2613. http://dx.doi.org/10.3390/ijms24032613.

Full text

Abstract:

Macrophages are heterogeneous and plastic cells, able to adapt their phenotype and functions to changes in the microenvironment. They are involved in several homeostatic processes and also in many human diseases, including atherosclerosis, where they participate in all the stages of the disease. For these reasons, macrophages have been studied extensively using different approaches, including proteomics. Proteomics, indeed, may be a powerful tool to better understand the behavior of these cells, and a careful analysis of the proteome of different macrophage phenotypes can help to better charac

APA, Harvard, Vancouver, ISO, and other styles

37

Maguire, P. B., M. Foy, and D. J. Fitzgerald. "Using proteomics to identify potential therapeutic targets in platelets." Biochemical Society Transactions 33, no. 2 (2005): 409–12. http://dx.doi.org/10.1042/bst0330409.

Full text

Abstract:

Proteomics has provided powerful new insights into the complex events of the anucleate platelet and has revealed many potential protein targets in the search for suitable agents for thrombotic disease. In the present study, we summarize recent proteomic approaches to analyse specific platelet subproteomes, such as the platelet releasate, the platelet phosphotyrosine proteome and characterization of the proteins associated with membrane lipid rafts.

APA, Harvard, Vancouver, ISO, and other styles

38

Mohanasundaram, Sugumar, Deepa Dhatwalia, P. Vijayaraghavan, Laith H. Alzubaidi, and Khamdamova Makhzuna. "Bioinformatics: Computational Approaches for Genomics and Proteomics." E3S Web of Conferences 399 (2023): 04042. http://dx.doi.org/10.1051/e3sconf/202339904042.

Full text

Abstract:

Bioinformatics is a fast evolving field that combines biology, computer science, and statistics to analyze and comprehend enormous volumes of biological data. As a result of the introduction of high-throughput technologies like next-generation sequencing and mass spectrometry, genomic and proteomics research has generated enormous volumes of data, necessitating the development of computational tools to process and extract useful insights from these datasets. This presentation presents a survey of computational approaches in bioinformatics with a particular emphasis on their application to geno

APA, Harvard, Vancouver, ISO, and other styles

39

González-Fernández, Raquel, Elena Prats, and Jesús V. Jorrín-Novo. "Proteomics of Plant Pathogenic Fungi." Journal of Biomedicine and Biotechnology 2010 (2010): 1–36. http://dx.doi.org/10.1155/2010/932527.

Full text

Abstract:

Plant pathogenic fungi cause important yield losses in crops. In order to develop efficient and environmental friendly crop protection strategies, molecular studies of the fungal biological cycle, virulence factors, and interaction with its host are necessary. For that reason, several approaches have been performed using both classical genetic, cell biology, and biochemistry and the modern, holistic, and high-throughput, omic techniques. This work briefly overviews the tools available for studying Plant Pathogenic Fungi and is amply focused on MS-based Proteomics analysis, based on original pa

APA, Harvard, Vancouver, ISO, and other styles

40

Koppel, Indrek, and Mike Fainzilber. "Omics approaches for subcellular translation studies." Molecular Omics 14, no. 6 (2018): 380–88. http://dx.doi.org/10.1039/c8mo00172c.

Full text

APA, Harvard, Vancouver, ISO, and other styles

41

Warren, Chad M., David L. Geenen, Donald L. Helseth,, Hua Xu, and R. John Solaro. "Sub-proteomic fractionation, iTRAQ, and OFFGEL-LC–MS/MS approaches to cardiac proteomics." Journal of Proteomics 73, no. 8 (2010): 1551–61. http://dx.doi.org/10.1016/j.jprot.2010.03.016.

Full text

APA, Harvard, Vancouver, ISO, and other styles

42

Paul, Debasish, Avinash Kumar, Akshada Gajbhiye, Manas K. Santra, and Rapole Srikanth. "Mass Spectrometry-Based Proteomics in Molecular Diagnostics: Discovery of Cancer Biomarkers Using Tissue Culture." BioMed Research International 2013 (2013): 1–16. http://dx.doi.org/10.1155/2013/783131.

Full text

Abstract:

Accurate diagnosis and proper monitoring of cancer patients remain a key obstacle for successful cancer treatment and prevention. Therein comes the need for biomarker discovery, which is crucial to the current oncological and other clinical practices having the potential to impact the diagnosis and prognosis. In fact, most of the biomarkers have been discovered utilizing the proteomics-based approaches. Although high-throughput mass spectrometry-based proteomic approaches like SILAC, 2D-DIGE, and iTRAQ are filling up the pitfalls of the conventional techniques, still serum proteomics importuna

APA, Harvard, Vancouver, ISO, and other styles

43

Kazieva, L. Sh, T. E. Farafonova, and V. G. Zgoda. "Antibody proteomics." Biomeditsinskaya Khimiya 69, no. 1 (2023): 5–18. http://dx.doi.org/10.18097/pbmc20236901005.

Full text

Abstract:

Antibodies represent an essential component of humoral immunity; therefore their study is important for molecular biology and medicine. The unique property of antibodies to specifically recognize and bind a certain molecular target (an antigen) determines their widespread application in treatment and diagnostics of diseases, as well as in laboratory and biotechnological practices. High specificity and affinity of antibodies is determined by the presence of primary structure variable regions, which are not encoded in the human genome and are unique for each antibody-producing B cell clone. Henc

APA, Harvard, Vancouver, ISO, and other styles

44

Rroji, Merita, Andreja Figurek, and Goce Spasovski. "Proteomic Approaches and Potential Applications in Autosomal Dominant Polycystic Kidney Disease and Fabry Disease." Diagnostics 13, no. 6 (2023): 1152. http://dx.doi.org/10.3390/diagnostics13061152.

Full text

Abstract:

Although rare, hereditary diseases, such as autosomal dominant polycystic kidney disease (ADPKD) and Fabry disease (FD) may significantly progress towards severe nephropathy. It is crucial to characterize it accurately, predict the course of the illness and estimate treatment effectiveness. A huge effort has been undertaken to find reliable biomarkers that might be useful for an early prevention of the disease progression and/or any invasive diagnostic procedures. The study of proteomics, or the small peptide composition of a sample, is a field of study under continuous development. Over the p

APA, Harvard, Vancouver, ISO, and other styles

45

Xu, Kai, and Peter D. Nagy. "Dissecting Virus-Plant Interactions Through Proteomics Approaches." Current Proteomics 7, no. 4 (2010): 316–27. http://dx.doi.org/10.2174/157016410793611792.

Full text

APA, Harvard, Vancouver, ISO, and other styles

46

Kapoor, Isha, Pooja Pal, Savita Lochab, Jitendra Kumar Kanaujiya, and Arun Kumar Trivedi. "Proteomics approaches for myeloid leukemia drug discovery." Expert Opinion on Drug Discovery 7, no. 12 (2012): 1165–75. http://dx.doi.org/10.1517/17460441.2012.724055.

Full text

APA, Harvard, Vancouver, ISO, and other styles

47

Korte, Robin, and Jens Brockmeyer. "Novel mass spectrometry approaches in food proteomics." TrAC Trends in Analytical Chemistry 96 (November 2017): 99–106. http://dx.doi.org/10.1016/j.trac.2017.07.010.

Full text

APA, Harvard, Vancouver, ISO, and other styles

48

Gingras, Anne-Claude, and Cassandra JJ Wong. "Proteomics approaches to decipher new signaling pathways." Current Opinion in Structural Biology 41 (December 2016): 128–34. http://dx.doi.org/10.1016/j.sbi.2016.07.008.

Full text

APA, Harvard, Vancouver, ISO, and other styles

49

Raghothama, Chaerkady, H. C. Harsha, C. K. Prasad, and Akhilesh Pandey. "Bioinformatics and Proteomics Approaches for Aging Research." Biogerontology 6, no. 4 (2005): 227–32. http://dx.doi.org/10.1007/s10522-005-2617-0.

Full text

APA, Harvard, Vancouver, ISO, and other styles

50

Ong, S. "Mass spectrometric-based approaches in quantitative proteomics." Methods 29, no. 2 (2003): 124–30. http://dx.doi.org/10.1016/s1046-2023(02)00303-1.

Full text

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!