Academic literature on the topic 'Protireline'

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Journal articles on the topic "Protireline"

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&NA;. "Protirelin." Reactions Weekly &NA;, no. 545 (1995): 12. http://dx.doi.org/10.2165/00128415-199505450-00043.

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&NA;. "Protirelin." Reactions Weekly &NA;, no. 725 (1998): 10–11. http://dx.doi.org/10.2165/00128415-199807250-00030.

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Duval, F., MC Mokrani, MA Crocq, et al. "Circadian variations in response to protirelin test in major depressive episode." European Psychiatry 6, no. 2 (1991): 79–88. http://dx.doi.org/10.1017/s0924933800000183.

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SummaryWe studied circadian thyrotropin (TSH) and prolactin (PRL) response to synthetic thyrotropin-releasing-hormone (protirelin) infusion (200μg IV) at 8 am and 11 pm in 35 drug-free inpatients with DSM III-R Major Depressive Episode and in 22 hospitalized controls. In each group, maximum TSH and PRL responses were lower at 8 am than at 11 pm. The difference between 11 pm-ΔTSH and 8 am-ΔJTSH (ΔΔTSH) was significantly lower in depressed patients compared to controls. No such blunting was observed in PRL responses to protirelin in depressed patients. In the overall population, TSH response to protirelin (ie8 am-ΔTSH, 11 pm-ΔTSH, ΔΔTSH) correlated significantly with TSH circadian parameters (ie mesor and amplitude). These correlations were also observed with PRL (except for ΔΔPRL). TSH mesor and amplitude were lower in depressives than in controls. In contrast, PRL mesor and amplitude were not significantly different between diagnostic groups. ΔΔTSH is thus a chronobiological refinement to the measure of thyroid axis dysfunction in major depression. The blunted TSH response to protirelin suggests that the TRH receptors of the pituitary thyrotrophs are hyposensitive in major depression.
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&NA;. "Protirelin/taltirelin." Reactions Weekly &NA;, no. 1395 (2012): 34. http://dx.doi.org/10.2165/00128415-201213950-00117.

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Takeuchi, Yoshihiro. "Thyrotropin-Releasing Hormone (Protirelin)." CNS Drugs 6, no. 5 (1996): 341–50. http://dx.doi.org/10.2165/00023210-199606050-00001.

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Kruger, TH, P. Haake, J. Haverkamp, et al. "Effects of acute prolactin manipulation on sexual drive and function in males." Journal of Endocrinology 179, no. 3 (2003): 357–65. http://dx.doi.org/10.1677/joe.0.1790357.

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The neuroendocrine response to sexual activity in humans is characterized by a pronounced orgasm-dependent increase of plasma levels of prolactin. In contrast to the well-known inhibitory effects of chronic hyperprolactinemia on sexual drive and function, the impact of acute prolactin alterations on human sexual physiology is unknown. Therefore, this study was designed to investigate the effects of acute manipulation of plasma prolactin on sexual behavior.Ten healthy males participated in a single-blind, placebo-controlled, balanced cross-over design. Prolactin levels were pharmacologically increased to high levels (protirelin, 50 micro g i.v.) or reduced to low physiological concentrations (cabergoline, 0.5 mg p.o.). Sexual arousal and orgasm were then induced by an erotic film and masturbation. In addition to continuous neuroendocrine and cardiovascular recordings, the quality and intensity of the acute sexual drive, arousal, orgasm and refractory period were assessed by extensive psychometric measures.Administration of cabergoline decreased prolactin levels and significantly enhanced all parameters of sexual drive (P<0.05), function (P<0.01) and positive perception of the refractory period (P<0.01). Administration of protirelin increased prolactin concentrations and produced small, but not significant reductions of sexual parameters. The sexual effects observed from cabergoline were completely abrogated by coadministration of protirelin. Although different pharmacological sites of action of prolactin-altering drugs have to be considered, these data demonstrate that acute changes in prolactin plasma levels may be one factor modulating sexual drive and function. Therefore, besides a neuroendocrine reproductive reflex, a post-orgasmic prolactin increase may represent one factor modulating central nervous system centers controlling sexual drive and behavior. These findings may offer a new pharmacological approach for the treatment of sexual disorders.
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&NA;. "Protirelin potentially harmful to neonates." Reactions Weekly &NA;, no. 558 (1995): 2. http://dx.doi.org/10.2165/00128415-199505580-00001.

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Garbutt, James C. "Dose-Response Studies With Protirelin." Archives of General Psychiatry 51, no. 11 (1994): 875. http://dx.doi.org/10.1001/archpsyc.1994.03950110035006.

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&NA;. "Antenatal protirelin not recommended for preterm births." Inpharma Weekly &NA;, no. 982 (1995): 14. http://dx.doi.org/10.2165/00128413-199509820-00026.

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&NA;. "Long-term adverse effects associated with protirelin?" Reactions Weekly &NA;, no. 645 (1997): 3. http://dx.doi.org/10.2165/00128415-199706450-00005.

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Dissertations / Theses on the topic "Protireline"

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COUMES, SENDRAL SYLVIE. "Test a la protireline r dans la maladie de basedow : valeur pronostique ; a propos de 57 observations." Toulouse 3, 1991. http://www.theses.fr/1991TOU31099.

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Books on the topic "Protireline"

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International Symposium on Protirelin Tartrate (TRH-T) (1988 Taormina, Italy). Protirelin tartrate (TRH-T): Pharmacological and clinical studies : recent advances and perspectives. Libbey, 1988.

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Book chapters on the topic "Protireline"

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"Protirelin." In Meyler's Side Effects of Drugs. Elsevier, 2016. http://dx.doi.org/10.1016/b978-0-444-53717-1.01364-0.

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Furman, Brian L. "Protirelin." In xPharm: The Comprehensive Pharmacology Reference. Elsevier, 2007. http://dx.doi.org/10.1016/b978-008055232-3.62486-9.

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Furman, B. L. "Protirelin☆." In Reference Module in Biomedical Sciences. Elsevier, 2017. http://dx.doi.org/10.1016/b978-0-12-801238-3.97178-2.

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"Protirelin." In Springer Reference Medizin. Springer Berlin Heidelberg, 2019. http://dx.doi.org/10.1007/978-3-662-48986-4_301401.

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"Protirelin." In Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions. Elsevier, 2006. http://dx.doi.org/10.1016/b0-44-451005-2/00974-8.

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