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Journal articles on the topic 'Protocatechuic acid'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

He, Cui, Lihua Yu, Wenran Dan, et al. "Application of a Simple Microfluidic Chip Analysis Technology to Evaluate the Inhibitory Role of Protocatechuic Acid on Shear-Induced Platelet Aggregation." Evidence-Based Complementary and Alternative Medicine 2021 (May 18, 2021): 1–11. http://dx.doi.org/10.1155/2021/5574413.

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This study aimed to develop a simple microfluidic chip analysis technology to study the inhibitory effect of protocatechuic acid on shear-induced platelet aggregation. The microfluidic chip designed in this study simulates 80% fixed narrow microchannels. This microchannel narrow model uses the finite element analysis module of the three-dimensional modeling software solidwork to analyze fluid dynamic behavior. Blood treated with protocatechuic acid at 1, 2, 4, 8, or 16 µg/mL was passed through the microchannel stenosis model at a shear rate of 10,000 s−1. The platelet adhesion and aggregation

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2

Khairnar, Upasana, Aman Upaganlawar, and Chandrashekhar Upasani. "Ameliorative Effect of Chronic Supplementation of Protocatechuic Acid Alone and in Combination with Ascorbic Acid in Aniline Hydrochloride Induced Spleen Toxicity in Rats." Scientifica 2016 (2016): 1–9. http://dx.doi.org/10.1155/2016/4306984.

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Background. Present study was designed to evaluate the protective effects of protocatechuic acid alone and in combination with ascorbic acid in aniline hydrochloride induced spleen toxicity in rats.Materials and Methods. Male Wistar rats of either sex (200–250 g) were used and divided into different groups. Spleen toxicity was induced by aniline hydrochloride (100 ppm) in drinking water for a period of 28 days. Treatment group received protocatechuic acid (40 mg/kg/day, p.o.), ascorbic acid (40 mg/kg/day, p.o.), and combination of protocatechuic acid (20 mg/kg/day, p.o.) and ascorbic acid (20

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3

Benitez, F. Javier, Jesus Beltran-Heredia, Teresa Gonzalez, and Juan L. Acero. "Photochemical oxidation of protocatechuic acid." Water Research 28, no. 10 (1994): 2095–100. http://dx.doi.org/10.1016/0043-1354(94)90019-1.

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4

Bernal-Mercado, Ariadna, Francisco Vazquez-Armenta, Melvin Tapia-Rodriguez, et al. "Comparison of Single and Combined Use of Catechin, Protocatechuic, and Vanillic Acids as Antioxidant and Antibacterial Agents against Uropathogenic Escherichia Coli at Planktonic and Biofilm Levels." Molecules 23, no. 11 (2018): 2813. http://dx.doi.org/10.3390/molecules23112813.

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The objective of this study was to evaluate the effect of combining catechin, protocatechuic, and vanillic acids against planktonic growing, adhesion, and biofilm eradication of uropathogenic Escherichia coli (UPEC), as well as antioxidant agents. The minimum inhibitory concentrations (MIC) of protocatechuic, vanillic acids and catechin against the growth of planktonic bacteria were 12.98, 11.80, and 13.78 mM, respectively. Mixing 1.62 mM protocatechuic acid + 0.74 mM vanillic acid + 0.05 mM catechin resulted in a synergistic effect acting as an MIC. Similarly, the minimum concentrations of ph

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5

Kennedy, JA, and HKJ Powell. "Aluminium(III) and Iron(III) 1,2-Diphenolato Complexes: a Potentiometric Study." Australian Journal of Chemistry 38, no. 5 (1985): 659. http://dx.doi.org/10.1071/ch9850659.

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The equilibrium reactions between aluminium(III) and the phenols catechol (LH2), protocatechuic acid (LH3) and catechin (LH4), and between iron(III) and protocatechuic acid have been studied by potentiometric titration in aqueous solution, I 0.10M ( KCl ), 25°C. Stability constants are reported for the mononuclear diphenolato complexes AlLHn-2, Al(LHn-2)2and Al(LHn-2)3, and the hydroxo complexes Al(OH)LHn-2 and Al(OH)(LHn-2)2, n = 2 ( catechol ) or 4 ( catechin ). For protocatechuic acid, the carboxylate -coordinated species lLH22+ and the species AlLH + (carboxyl- protonated ) are also postul

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6

Krajka-Kuźniak, Violetta, Adam Krysztofiak, and Jarosław Paluszczak. "Induction of UDP-glucuronosyltransferase 1A by naturally occurring phytochemicals in human hepatoma cells." Journal of Medical Science 83, no. 3 (2014): 209–14. http://dx.doi.org/10.20883/medical.e69.

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UDP-glucuronosyltransferases (UGTs) are important detoxification and drug-metabolizing enzymes, which catalyse the glucuronidation of exogenous and endogenous chemicals. The anti-carcinogenic activity of dietary phytochemicals is partly attributed to the induction of phase II enzymes, including UGT1A. Our earlier study showed that protocatechuic acid increased UGT activity in rat liver. A similar effect was observed for indole-3-carbinol and phenethyl isothiocyanate in rat liver. In this study we assessed the effect of protocatechuic acid, tannic acid, indole-3-carbinol and phenethyl isothiocy

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7

Omori, Toshio, Kazuhisa Hatakeyama, and Tohru Kodama. "Protocatechuic acid production from trans-ferulic acid by Pseudomonas sp. HF-1 mutants defective in protocatechuic acid catabolism." Applied Microbiology and Biotechnology 29, no. 5 (1988): 497–500. http://dx.doi.org/10.1007/bf00269075.

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8

Shen, Jie, Kai Yang, Caihua Sun, and Minxia Zheng. "Analysis of Active Components in Salvia Miltiorrhiza Injection Based on Vascular Endothelial Cell Protection." Acta Pharmaceutica 64, no. 3 (2014): 325–34. http://dx.doi.org/10.2478/acph-2014-0027.

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Abstract Correlation analysis based on chromatograms and pharmacological activities is essential for understanding the effective components in complex herbal medicines. In this report, HPLC and measurement of antioxidant properties were used to describe the active ingredients of Salvia miltiorrhiza injection (SMI). HPLC results showed that tanshinol, protocatechuic aldehyde, rosmarinic acid, salvianolic acid B, protocatechuic acid and their metabolites in rat serum may contribute to the efficacy of SMI. Assessment of antioxidant properties indicated that differences in the composition of serum

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9

Breuer, Matthias, Gerhard Leeder, Peter Proksch, and Budzikiewicz Herbert. "Protocatechuic acid derivatives from Hemizonia lobbii." Phytochemistry 25, no. 2 (1986): 495–97. http://dx.doi.org/10.1016/s0031-9422(00)85508-9.

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10

JAVIERBENITEZ, F. "Protocatechuic acid ozonation in aqueous solutions." Water Research 27, no. 10 (1993): 1519–25. http://dx.doi.org/10.1016/0043-1354(93)90096-z.

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11

Xu, Yang, Yuejie Wang, Shengnan Bi, Yanxue Jia, and Huiwei Bao. "Simultaneous Determination of Four Ingredients in Plantago Depressa by Single Marker." Journal of Chemistry 2021 (December 21, 2021): 1–8. http://dx.doi.org/10.1155/2021/4040239.

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Objective. To establish a quantitative analysis of multicomponents by single marker (QAMS) method for the simultaneous determination of 4 active components such as protocatechuic acid, catechin, quercetin, and luteolin in Plantago depressa. Method. 4 active components in Plantago depressa were studied. Quercetin was used as an internal reference to establish the relative correction factors among protocatechuic acid, catechin, and luteolin and calculate the contents of each component; the results were compared with those measured by the external standard method. Results. 4 components showed a g

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12

Li, Xin-Pu, Jie Yu, Jin-Yin Luo, et al. "Simultaneous Determination of Chlorogenic Acid, Caffeic Acid, Ferulic Acid, Protocatechuic Acid and Protocatechuic Aldehyde in Chinese Herbal Preparation by RP-HPLC." CHEMICAL & PHARMACEUTICAL BULLETIN 52, no. 10 (2004): 1251–54. http://dx.doi.org/10.1248/cpb.52.1251.

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13

Phanthong, Phanida, Noppawan Phumala Morales, Sirirat Chancharunee, Supachoke Mangmool, Natthinee Anantachoke, and Nuntavan Bunyapraphatsara. "Biological Activity of Dolichandrone Serrulata Flowers and Their Active Components." Natural Product Communications 10, no. 8 (2015): 1934578X1501000. http://dx.doi.org/10.1177/1934578x1501000819.

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Dolichandrone serrulata (DC.) Seem flowers are widely used as vegetables in northern and eastern Thailand. Biological studies of the methanolic extract of these flowers have shown promising antioxidant activity. Biological-guided separation of D. serrulata flowers yielded six compounds, identified as hallerone, protocatechuic acid, rengyolone, cleroindicin B, ixoside, and isomaltose. This is the first report on hallerone, protocatechuic acid, rengyolone, cleroindicin B, and isomaltose in D. serrulata. Protocatechuic acid was the most potent scavenger of 2,2-diphenyl-l-picrylhydrazyl and hydrox

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14

Wang, Lili, Huifeng Xu, Lishuang Yu, et al. "Simultaneous Separation and Analysis of Five Compounds in Cibotium barometz by Micellar Electrokinetic Chromatography with Large-Volume Sample Stacking." Separations 8, no. 9 (2021): 147. http://dx.doi.org/10.3390/separations8090147.

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A large volume sample stacking (LVSS) method in micellar electrokinetic chromatography (MEKC) with diode array detector was developed for the simultaneous separation and analysis of five compounds: protocatechuic acid, protocatechuic aldehyde, caffeic acid, syringetin and vanillin in Cibotium barometz. The electrophoretic separation was performed in a 10 mM sodium dodecyl sulfate (SDS) and 50 mM sodium borax-sodium dihydrogen phosphate system (pH = 8.5) with 10% methanol at a separation voltage of 30 kV after optimizing the typical parameters. The detection limits were from 32 pg to 65 pg, whi

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15

Elansary, Hosam O., Agnieszka Szopa, Paweł Kubica, Diaa O. El-Ansary, Halina Ekiert, and Fahed A. Al-Mana. "Malus baccata var. gracilis and Malus toringoides Bark Polyphenol Studies and Antioxidant, Antimicrobial and Anticancer Activities." Processes 8, no. 3 (2020): 283. http://dx.doi.org/10.3390/pr8030283.

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Exploring new sources of polyphenols with biological activities that work against human diseases is the target of natural product studies. This study determined the polyphenol composition of the bark of Malus species M. baccata var. gracilis (Rehder) T.C.Ku and M. toringoides (Rehder) Hughes, using high-performance liquid chromatography with a diode-array detector (HPLC-DAD) analysis. The antiproliferative, cytotoxic, antioxidant and antimicrobial applications of these extracts, as well as the identified phenol, were studied. The HPLC-DAD analysis confirmed three polyphenols in the extracts ou

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16

Tatsumi, K., S. Wada, H. Ichikawa, S. Y. Liu, and Jean-Marc Bollag. "Cross-Coupling of a Chloroaniline and Phenolic Acids Catalyzed by a Fungal Enzyme." Water Science and Technology 26, no. 9-11 (1992): 2157–60. http://dx.doi.org/10.2166/wst.1992.0685.

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The reaction between 3,4-dichloroaniline and vanillic, syringic and protocatechuic acids was investigated in the presence of a laccase isolated from the fungus Rhizoctoniapraticola. The aniline alone was not oxidized by the laccase, but if incubated with the phenolic acids and the laccase, cross-linking took place. Particularly the protocatechuic acid and syringic acid reacted with 3,4-dichloroaniline, and cross-linked dimers were isolated as main products.

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17

Costa-Lotufo, Letícia V., Paula C. Jimenez, Diego V. Wilke, et al. "Antiproliferative Effects of Several Compounds Isolated from Amburana cearensis A. C. Smith." Zeitschrift für Naturforschung C 58, no. 9-10 (2003): 675–80. http://dx.doi.org/10.1515/znc-2003-9-1014.

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AbstractAmburana cearensis a common tree found in Northeastern Brazil is widely used in folk medicine. The present work evaluated the cytotoxicity of kaempferol, isokaempferide, amburoside A and protocatechuic acid isolated from the ethanol extract of the trunk bark of A. cearensis. The compounds were tested for their cytotoxicity on the sea urchin egg development, hemolysis assay and 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide assay using tumor cell lines. Isokaempferide and kaempferol, but not amburoside A and protocatechuic acid, inhibited the sea urchin egg development

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18

Conde, Mireia, Maria Mercè Solé, Sílvia Sorolla, Concepció Casas, and Anna Bacardit. "Electrospray Ionization—Mass Spectrometry Characterization of Pine Bark Extracts." NDT 2, no. 2 (2024): 143–59. http://dx.doi.org/10.3390/ndt2020009.

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This study explored the potential application of polyphenols from Pinus halepensis bark in leather tanning. The primary objective was to characterize these polyphenols. The extraction and atomization processes proved efficient, reducing moisture content to 7.4%, increasing tannin content from 26.2% to 45.1%, and reducing insoluble substances by 77.5%. High-performance liquid chromatography (HPLC) coupled with mass spectrometry identified and quantified various polyphenolic compounds, including (+)-catechin, (+)-taxifolin, protocatechuic acid, and procyanidin B2. Notably, tannic catechin dimers

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19

Shi, Wenxiu, Junxia Wang, Lei Zhu, Meizhi Cai, and Xiaoyan Du. "Electrochemical Determination of Catechin, Protocatechuic Acid, and L-Lactic Acid Based on Voltammetric Response of Ferroceneboronic Acid." Journal of AOAC INTERNATIONAL 97, no. 6 (2014): 1742–45. http://dx.doi.org/10.5740/jaoacint.13-366.

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Abstract An electrochemical technique for the determination of catechin, protocatechuic acid, and L-lactic acid has been developed using ferroceneboronic acid (FBA) as an electrochemical probe. The principle is based on the changes in voltammograms of FBA associated with selective binding of the analytes to FBA. A cyclic voltammogram and a differential pulse voltammogram (DPV) of FBA were recorded on a glassy carbon electrode in the presence of the analytes. The oxidation or reduction peak currents of FBA were decreased in the presence of the analytes, depending on their concentrations. The DP

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20

Torrisi, Cristina, Giuseppe Antonio Malfa, Rosaria Acquaviva, Francesco Castelli, and Maria Grazia Sarpietro. "Effect of Protocatechuic Acid Ethyl Ester on Biomembrane Models: Multilamellar Vesicles and Monolayers." Membranes 12, no. 3 (2022): 283. http://dx.doi.org/10.3390/membranes12030283.

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The interactions of drugs with cell membranes are of primary importance for several processes involved in drugs activity. However, these interactions are very difficult to study due to the complexity of biological membranes. Lipid model membranes have been developed and used to gain insight into drug–membrane interactions. In this study, the interaction of protocatechuic acid ethyl ester, showing radical-scavenging activity, antimicrobial, antitumor and anti-inflammatory effects, with model membranes constituted by multilamellar vesicles and monolayers made of DMPC and DSPC, has been studied.

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21

Zhang, Shijun, Zhibo Gai, Ting Gui, Juanli Chen, Qingfa Chen, and Yunlun Li. "Antioxidant Effects of Protocatechuic Acid and Protocatechuic Aldehyde: Old Wine in a New Bottle." Evidence-Based Complementary and Alternative Medicine 2021 (November 8, 2021): 1–19. http://dx.doi.org/10.1155/2021/6139308.

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Phenolic compounds are naturally present as secondary metabolites in plant-based sources such as fruits, vegetables, and spices. They have received considerable attention for their antioxidant, anti-inflammatory, and anti-carcinogenic properties for protection against many chronic disorders such as neurodegenerative diseases, diabetes, cardiovascular diseases, and cancer. They are categorized into various groups based on their chemical structure and include phenolic acids, flavonoids, curcumins, tannins, and quinolones. Their structural variations contribute to their specific beneficial effect

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22

Gutierrez-Zetina, Sofia, Susana Gonzalez-Manzano, Jose Perez-Alonso, Ana Gonzalez-Paramas, and Celestino Santos-Buelga. "Preparation and Characterization of Protocatechuic Acid Sulfates." Molecules 24, no. 2 (2019): 307. http://dx.doi.org/10.3390/molecules24020307.

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Protocatechuic acid (3,4-dihydroxybenzoic acid; PCA) is a phenolic acid present in plants as a secondary metabolite and is also produced in the human organism as a metabolite from the degradation of polyphenols by the intestinal microbiota, particularly of flavonoids. However, PCA, like most polyphenols, is biotransformed in the human body to different conjugates as sulfates, which are found circulating in blood and could be involved in the bioactivity of the original compound. This paper describes a simple process for the preparation of PCA monosulfates with satisfactory yields. Two compounds

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23

Boominathan, K., and A. Mahadevan. "Degradation of protocatechuic acid by Pseudomonas solanacearum." Zentralblatt für Mikrobiologie 147, no. 7 (1992): 483–87. http://dx.doi.org/10.1016/s0232-4393(11)80320-3.

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24

Tanaka, Takuji, Takahiro Tanaka, and Mayu Tanaka. "Potential Cancer Chemopreventive Activity of Protocatechuic Acid." Journal of Experimental & Clinical Medicine 3, no. 1 (2011): 27–33. http://dx.doi.org/10.1016/j.jecm.2010.12.005.

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25

Galvano, Fabio, Paola Vitaglione, Giovanni Li Volti, et al. "Protocatechuic acid: The missing human cyanidins' metabolite." Molecular Nutrition & Food Research 52, no. 3 (2008): 386–87. http://dx.doi.org/10.1002/mnfr.200890011.

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26

Zhang, H. Y., Z. D. Hu, G. L. Yang, Z. H. Shi та H. W. Sun. "Determination of β-(3,4-dihydroxyphenyl) lactic acid, protocatechuic acid and protocatechuic aldehyde in radixSalviae Miltiorrhizae by capillary electrophoresis". Chromatographia 49, № 3-4 (1999): 219–22. http://dx.doi.org/10.1007/bf02575290.

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27

Iqbal, M., M. Asif Shahab, Mohsin Ali Hassni, Sana Dur Muhammad, Shehroz Bashir, and Shah Murad. "Caffeic Acid, Chlorogenic Acid, Garlic Acid, and Protocatechuic Acid as Hypolipidemic Agents." SAR Journal of Pathology and Microbiology 4, no. 06 (2023): 82–85. http://dx.doi.org/10.36346/sarjpm.2023.v04i06.005.

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As the pathophysiology of dyslipidemias is clarified, one system is likely to emerge in which the underlying mechanism explains the phenotypic pattern observed on lipoprotein analysis. Every day, millions of vials of blood are drawn to assess patients’ risk for the disease. These tests measure three biomarkers, or factors in the blood known to be associated with CAD: low-density lipoproteins (LDL cholesterol), high-density lipoproteins (HDL cholesterol), and triglycerides. All three biomarkers are lipids – water-insoluble molecules that are among the structural and functional building blocks o

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28

Guglielmi, Francesco, Cristina Luceri, Lisa Giovannelli, Piero Dolara, and Maura Lodovici. "Effect of 4-coumaric and 3,4-dihydroxybenzoic acid on oxidative DNA damage in rat colonic mucosa." British Journal of Nutrition 89, no. 5 (2003): 581–87. http://dx.doi.org/10.1079/bjn2003849.

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The effect of 4-coumaric and 3,4-dihydroxybenzoic (protocatechuic) acid on the basal oxidative DNA damage of rat colonic mucosa in vivo was studied, relative to vitamin E. F344 rats were treated with 4-coumaric or protocatechuic acid mixed in the diet (25 or 50 mg/kg for 2 weeks). It was observed that 4-coumaric acid (50 mg/kg) significantly decreased the basal level of the oxidative damage assessed as 8-OH-2′-deoxyguanosine levels in DNA and by the comet assay. Moreover, it was found that vitamin E (10 mg/kg) had no effect on colonic mucosa oxidation damage, whereas at a higher dose (55 mg/kg

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29

Cao, Qin, Junhan Li, Yu Xia, et al. "Green Extraction of Six Phenolic Compounds from Rattan (Calamoideae faberii) with Deep Eutectic Solvent by Homogenate-Assisted Vacuum-Cavitation Method." Molecules 24, no. 1 (2018): 113. http://dx.doi.org/10.3390/molecules24010113.

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A homogenate-assisted vacuum-cavitation extraction (HVE) method with a “green” solvent (a deep eutectic solvent, DES) was developed to extract phenolic compounds from rattan (Calamoideae faberii). In this study, the optimum molar ratio of choline chloride (ChCl) and ethylene glycol (EG) was 1:3, the optimum volume ratio of ChCl-EG:H2O was 6:4, the solid-liquid ratio of HVE was 1:15, and the extraction time of homogenate and vacuum-cavitation were 2.0 min and 25 min, respectively. Under the optimum parameters of HVE, the extraction yield of total phenolic content with ChCl-EG solution was 6.82

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Srivastava, Nishi, Amit Srivastava, S. Srivastava, A. K. S. Rawat, and A. R. Khan. "HPTLC-densitometric determination and kinetic studies on antioxidant potential of monomeric phenolic acids (MPAs) from Bergenia species." RSC Adv. 4, no. 95 (2014): 52647–57. http://dx.doi.org/10.1039/c4ra09330e.

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We developed a HPTLC method for the quantification of vanillic acid, syringic acid, gallic acid and protocatechuic acid and kinetic studies on antioxidant potential in Bergenia ciliata and Bergenia stracheyi.

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Longe, Lionel, Gil Garnier, and Kei Saito. "Synthesis of Lignin-based Phenol Terminated Hyperbranched Polymer." Molecules 24, no. 20 (2019): 3717. http://dx.doi.org/10.3390/molecules24203717.

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In this work, we proved the efficient synthesis of a bio-based hyper-branched polyphenol from a modified lignin degradation fragment. Protocatechuic acid was readily obtained from vanillin, a lignin degradation product, via alkaline conditions, and further polymerised to yield high molecular weight hyperbranched phenol terminated polyesters. Vanillic acid was also subjected to similar polymerisation conditions in order to compare polymerisation kinetics and differences between linear and hyperbranched polymers. Overall, protocatechuic acid was faster to polymerise and more thermostable with a

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Kadakol, Jagannath C., and Chandrappa M. Kamanavalli. "Biodegradation of Eugenol byBacillus CereusStrain PN24." E-Journal of Chemistry 7, s1 (2010): S474—S480. http://dx.doi.org/10.1155/2010/364637.

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Bacillus cereusPN24 was isolated from soil by a conventional enrichment culture method using eugenol as a sole source of carbon and energy. The organism also utilized eugenol, 4-vinyl guaiacol, vanillin, vanillic acid and protocatechuic acid as growth substrates. The organism degraded eugenol to protocatechuic acid, which was further metabolized by aβ-ketoadipate pathway. On the other hand, the intermediate of the eugenol-degrading pathway, such as ferulic acid was not detected in the culture medium as an intermediate, as evidenced by isolation and identification of metabolites and enzyme acti

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Pawar, Reshma, and A. Balasubramaniam. "Densitometric HPTLC analysis of the Acacia catechu wild fractions for phenolics." International Journal of Experimental Research and Review 32 (August 30, 2023): 260–69. http://dx.doi.org/10.52756/ijerr.2023.v32.022.

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Traditional "Ayurvedic" medicine from India has traditionally used Acacia catechu. The herbal extract is the primary component, although there have been no attempts to standardize it as an active agent or marker. A chromatographic fingerprint represents the chemical components of herbal remedies that are therapeutically advantageous. This study suggests utilizing an HPTLC approach to assess phenols like protocatechuic acid and gallic acid in Acacia catechu extract fractions made of water, ethyl acetate, and butanol. According to the study, protocatechuic acid (11.85%) in the water fraction of

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Bubinas, Audrius, Gražina Giedraitytė, Lilija Kalėdienė, Ona Nivinskiene, and Rita Butkiene. "Degradation of naphthalene by thermophilic bacteria via a pathway, through protocatechuic acid." Open Life Sciences 3, no. 1 (2008): 61–68. http://dx.doi.org/10.2478/s11535-007-0042-x.

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AbstractA number of thermophilic bacteria capable of utilizing naphthalene as a sole source of carbon were isolated from a high-temperature oilfield in Lithuania. These isolates were able to utilize several other aromatic compounds, such as anthracene, benzene, phenol, benzene-1, 3-diol, protocatechuic acid as well. Thermophilic isolate G27 ascribed to Geobacillus genus was found to have a high aromatic compound degrading capacity. Spectrophotometric determination of enzyme activities in cell-free extracts revealed that the last aromatic ring fission enzyme in naphthalene biotransformation by

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35

Udeh, Henry, Kwaku Duodu, and Afam Jideani. "Malting Period Effect on the Phenolic Composition and Antioxidant Activity of Finger Millet (Eleusine coracana L. Gaertn) Flour." Molecules 23, no. 9 (2018): 2091. http://dx.doi.org/10.3390/molecules23092091.

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The present study examined the influence of malting on the phenolic composition of two cultivars of finger millet using an ultra-performance liquid chromatography mass spectrometer. Total polyphenols and antioxidant activities of the grains were also evaluated using sorghum as an external reference. Catechin, epicatechin, quercetin, taxifolin, and hesperitin were isolated flavonoids, whereas protocatechuic acid was the phenolic acid detected in finger millet malt. Increases in the content of catechin, epicatechin, and protocatechuic acid were observed for 72 h and 96 h for brown finger millet

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36

Zhao, Yimin, Zouyan He, Wangjun Hao, et al. "Cholesterol-lowering activity of protocatechuic acid is mediated by increasing the excretion of bile acids and modulating gut microbiota and producing short-chain fatty acids." Food & Function 12, no. 22 (2021): 11557–67. http://dx.doi.org/10.1039/d1fo02906a.

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Han, Suqin, Erbao Liu, and Hua Li. "On-line chemiluminescence determination protocatechuic aldehyde and protocatechuic acid in pharmaceutical preparations by capillary electrophoresis." Journal of Pharmaceutical and Biomedical Analysis 37, no. 4 (2005): 733–38. http://dx.doi.org/10.1016/j.jpba.2004.11.045.

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38

Saleem, Ammar, and Henri Kivelä. "Antioxidant Activity of Pine Bark Constituents." Zeitschrift für Naturforschung C 58, no. 5-6 (2003): 351–54. http://dx.doi.org/10.1515/znc-2003-5-611.

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AbstractA modified in vitro lipid peroxidation inhibition assay was used to guide the fractionation and the isolation of antioxidative principles of Finnish pine bark extract. This approach yielded 3,4-dihydroxybenzoic acid (protocatechuic acid) and taxifolin-3-O-β-glucopyranoside as major antioxidative compounds from the plant material. The structural elucidation of these compounds was undertaken with the help of HPLC-DAD and HPLC-ESI-MS analyses. Their IC50 values, in comparison to trolox (6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid), were: trolox (1.78 ± 0.56 μm) < protocatech

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Xi, Xiujuan, Shiqi Hu, Zhuxian Zhou, Xiangrui Liu, Jianbin Tang, and Youqing Shen. "Dendrimers with the protocatechuic acid building block for anticancer drug delivery." Journal of Materials Chemistry B 4, no. 31 (2016): 5236–45. http://dx.doi.org/10.1039/c6tb01597b.

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Daniel, I. J., E. Innocent, J. Sempombe, V. Mugoyela, and T. Fossen. "Isolation and Characterization of Larvicidal Phenolic Acids from Kotschya thymodora Leaves." Journal of Applied Sciences and Environmental Management 24, no. 8 (2020): 1483–88. http://dx.doi.org/10.4314/jasem.v24i8.26.

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Malaria is a vector borne disease responsible for high morbidity, mortality and poverty in many tropical and subtropical countries. The disease is transmitted through a bite from an infected female Anopheles mosquito, amongst which Anopheles gambiae s.s serves as the most prevalent vector. The control of An. gambiae s.s population can therefore lead to a reduction in malaria spreading. Previous studies have reported the crude extracts of Kotschya thymodora to be active against the larvae of An. gambiae s.s and Culex quinquefasciatus. In this report the phytochemical study on the crude aqueous

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Mikstacka, Renata, Jerzy Gnojkowski, and Wanda Baer-Dubowska. "Effect of natural phenols on the catalytic activity of cytochrome P450 2E1." Acta Biochimica Polonica 49, no. 4 (2002): 917–25. http://dx.doi.org/10.18388/abp.2002_3751.

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The effect of protocatechuic acid, tannic acid and trans-resveratrol on the activity of p-nitrophenol hydroxylase (PNPH), an enzymatic marker of CYP2E1, was examined in liver microsomes from acetone induced mice. trans-Resveratrol was found to be the most potent inhibitor (IC(50) = 18.5 +/- 0.4 microM) of PNPH, while protocatechuic acid had no effect on the enzyme activity. Tannic acid with IC(50) = 29.6 +/- 3.3 microM showed mixed- and trans-resveratrol competitive inhibition kinetics (K(i) = 1 microM and 2.1 microM, respectively). Moreover, trans-resveratrol produced a NADPH-dependent loss o

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Zhang, Ren-Kuan, Yong-Shui Tan, You-Zhi Cui, et al. "Lignin valorization for protocatechuic acid production in engineered Saccharomyces cerevisiae." Green Chemistry 23, no. 17 (2021): 6515–26. http://dx.doi.org/10.1039/d1gc01442k.

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Tatsumi, Kenji, Alan Freyer, Robert D. Minard, and Jean-Marc Bollag. "Enzymatic coupling of chloroanilines with syringic acid, vanillic acid and protocatechuic acid." Soil Biology and Biochemistry 26, no. 6 (1994): 735–42. http://dx.doi.org/10.1016/0038-0717(94)90266-6.

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Beh, Boon Kee, Nurul Elyani Mohamad, Swee Keong Yeap, et al. "Polyphenolic profiles and the in vivo antioxidant effect of nipa vinegar on paracetamol induced liver damage." RSC Advances 6, no. 68 (2016): 63304–13. http://dx.doi.org/10.1039/c6ra13409b.

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Domínguez-López, Inés, Polina Galkina, Moser Isabella Parilli, et al. "Microbial Phenolic Metabolites Are Associated with Improved Cognitive Health." Molecular Nutrition & Food Research 68, no. 2 (2023): e2300183. https://doi.org/10.1002/mnfr.202300183.

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Scope: Diets rich in polyphenols has been associated with better cognitive performance. The aim of this study is to assess the relationship between microbial phenolic metabolites (MPM) in urine and cognition in the context of an older population at high cardiovascular risk.Methods and results: A cross-sectional analysis is conducted in 400 individuals of the PREDIMED-Plus study. Liquid chromatography coupled to mass spectrometry is used to identify urinary MPM. Mediterranean diet (MedDiet) adherence is estimated with a 17-item questionnaire and cognitive function is evaluated with a battery of

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Williams, Kimtrele M., William E. Martin, Justin Smith, Baraka S. Williams, and Bianca L. Garner. "Production of Protocatechuic Acid in Bacillus Thuringiensis ATCC33679." International Journal of Molecular Sciences 13, no. 3 (2012): 3765–72. http://dx.doi.org/10.3390/ijms13033765.

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Wei, Miaomiao, Xiao Chu, Lanxiang Jiang, et al. "Protocatechuic Acid Attenuates Lipolysaccharide-Induced Acute Lung Injury." Inflammation 35, no. 3 (2012): 1169–78. http://dx.doi.org/10.1007/s10753-011-9425-2.

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Minh, Luong The, Do Tan Khang, Pham Thi Thu Ha, et al. "Effects of Salinity Stress on Growth and Phenolics of Rice (Oryza sativa L.)." International Letters of Natural Sciences 57 (August 2016): 1–10. http://dx.doi.org/10.18052/www.scipress.com/ilns.57.1.

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This study was conducted to determine the correlation between of salinity stress on growth and phenolic compounds in rice. It was observed that salinity stress caused a significant decrease in shoot lengths, fresh and dry weights of all rice varieties. Under salinity stress, changes of chemical contents also differed among phenolic compounds and rice cultivars. Total phenolics and flavonoids, and contents of vanillin and protocatechuic acid in tolerant varieties were strongly increased, whereas in contrast, they were markedly reduced in the susceptible cultivar. Ferulic acid and p-coumaric aci

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Minh, Luong The, Do Tan Khang, Pham Thi Thu Ha, et al. "Effects of Salinity Stress on Growth and Phenolics of Rice (<i>Oryza sativa</i> L.)." International Letters of Natural Sciences 57 (August 3, 2016): 1–10. http://dx.doi.org/10.56431/p-f1p658.

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This study was conducted to determine the correlation between of salinity stress on growth and phenolic compounds in rice. It was observed that salinity stress caused a significant decrease in shoot lengths, fresh and dry weights of all rice varieties. Under salinity stress, changes of chemical contents also differed among phenolic compounds and rice cultivars. Total phenolics and flavonoids, and contents of vanillin and protocatechuic acid in tolerant varieties were strongly increased, whereas in contrast, they were markedly reduced in the susceptible cultivar. Ferulic acid and p-coumaric aci

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Réblová, Z. "Effect of temperature on the antioxidant activity of phenolic acids." Czech Journal of Food Sciences 30, No. 2 (2012): 171–75. http://dx.doi.org/10.17221/57/2011-cjfs.

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The effect of temperature on the antioxidant activity of phenolic acids (gallic, gentisic, protocatechuic, syringic, vanillic, ferulic, caffeic, and sinapic; 0.5 mmol/kg) was studied in pork lard, using an Oxipres apparatus, at a temperature range of 90&deg;C to 150&deg;C. The antioxidant activity of all studied compounds decreased with increasing working temperature, whereas a linear relationship (P &lt; 0.01) existed between temperature and the antioxidant activity in all cases. However, the relative rate of the antioxidant activity decrease with increasing temperature (i.e. in c

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