Academic literature on the topic 'Protometabolism'

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Journal articles on the topic "Protometabolism"

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de Duve, Christian. "From protometabolism to metabolism." Origins of life and evolution of the biosphere 24, no. 2-4 (1994): 346–62. http://dx.doi.org/10.1007/bf02627949.

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Broecker, Felix. "Genome Evolution from Random Ligation of RNAs of Autocatalytic Sets." International Journal of Molecular Sciences 22, no. 24 (2021): 13526. http://dx.doi.org/10.3390/ijms222413526.

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The evolutionary origin of the genome remains elusive. Here, I hypothesize that its first iteration, the protogenome, was a multi-ribozyme RNA. It evolved, likely within liposomes (the protocells) forming in dry-wet cycling environments, through the random fusion of ribozymes by a ligase and was amplified by a polymerase. The protogenome thereby linked, in one molecule, the information required to seed the protometabolism (a combination of RNA-based autocatalytic sets) in newly forming protocells. If this combination of autocatalytic sets was evolutionarily advantageous, the protogenome would
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Pratt, Andrew J. "Prebiological Evolution and the Metabolic Origins of Life." Artificial Life 17, no. 3 (2011): 203–17. http://dx.doi.org/10.1162/artl_a_00032.

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The chemoton model of cells posits three subsystems: metabolism, compartmentalization, and information. A specific model for the prebiological evolution of a reproducing system with rudimentary versions of these three interdependent subsystems is presented. This is based on the initial emergence and reproduction of autocatalytic networks in hydrothermal microcompartments containing iron sulfide. The driving force for life was catalysis of the dissipation of the intrinsic redox gradient of the planet. The codependence of life on iron and phosphate provides chemical constraints on the ordering o
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Kitadai, Norio, Ryuhei Nakamura, Masahiro Yamamoto, Ken Takai, Naohiro Yoshida, and Yoshi Oono. "Metals likely promoted protometabolism in early ocean alkaline hydrothermal systems." Science Advances 5, no. 6 (2019): eaav7848. http://dx.doi.org/10.1126/sciadv.aav7848.

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One of the most plausible scenarios of the origin of life assumes the preceding prebiotic autotrophic metabolism in sulfide-rich hydrothermal vent environments. However, geochemical mechanisms to harness the reductive power provided by hydrothermal systems remain to be elucidated. Here, we show that, under a geoelectrochemical condition realizable in the early ocean hydrothermal systems, several metal sulfides (FeS, Ag2S, CuS, and PbS) undergo hour- to day-scale conversion to the corresponding metals at ≤−0.7 V (versus the standard hydrogen electrode). The electrochemically produced FeS-Fe0 as
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Hagan, William J. "Uracil-Catalyzed Synthesis of Acetyl Phosphate: A Photochemical Driver for Protometabolism." ChemBioChem 11, no. 3 (2010): 383–87. http://dx.doi.org/10.1002/cbic.200900433.

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Patel, Bhavesh H., Claudia Percivalle, Dougal J. Ritson, Colm D. Duffy, and John D. Sutherland. "Common origins of RNA, protein and lipid precursors in a cyanosulfidic protometabolism." Nature Chemistry 7, no. 4 (2015): 301–7. http://dx.doi.org/10.1038/nchem.2202.

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Monreal Santiago, Guillermo, Kai Liu, Wesley R. Browne, and Sijbren Otto. "Emergence of light-driven protometabolism on recruitment of a photocatalytic cofactor by a self-replicator." Nature Chemistry 12, no. 7 (2020): 603–7. http://dx.doi.org/10.1038/s41557-020-0494-4.

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Emond, Matthieu, Thomas Le Saux, Jean-Francois Allemand, Philippe Pelupessy, Raphaël Plasson, and Ludovic Jullien. "Energy Propagation Through a Protometabolism Leading to the Local Emergence of Singular Stationary Concentration Profiles." Chemistry - A European Journal 18, no. 45 (2012): 14375–83. http://dx.doi.org/10.1002/chem.201201974.

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Zhou, Xianfeng, Punam Dalai, and Nita Sahai. "Semipermeable Mixed Phospholipid-Fatty Acid Membranes Exhibit K+/Na+ Selectivity in the Absence of Proteins." Life 10, no. 4 (2020): 39. http://dx.doi.org/10.3390/life10040039.

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Two important ions, K+ and Na+, are unequally distributed across the contemporary phospholipid-based cell membrane because modern cells evolved a series of sophisticated protein channels and pumps to maintain ion gradients. The earliest life-like entities or protocells did not possess either ion-tight membranes or ion pumps, which would result in the equilibration of the intra-protocellular K+/Na+ ratio with that in the external environment. Here, we show that the most primitive protocell membranes composed of fatty acids, that were initially leaky, would eventually become less ion permeable a
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Helman, Daniel S., and Matthew Retallack. "Electrochemical cells from water ice? Preliminary methods and results." PLOS ONE 18, no. 8 (2023): e0285507. http://dx.doi.org/10.1371/journal.pone.0285507.

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Electrochemical cells from ice will be an important seasonal addition to power generation in cold regions. We demonstrate power generation on the order of 0.1 mW at 0.3 V and 0.13 m2 surface area using an electrochemical cell with 2% HCl providing a pH gradient in ice, and suggest a solar add-on effect due to temperature changes under direct sunlight. Different models are discussed, and data are presented related to different additives: (1) solutes such as NaCl and monopotassium phosphate; (2) pH modifying agents such as acids and bases; (3) particulate suspensions with kaolinite and other sub
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Dissertations / Theses on the topic "Protometabolism"

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Coggins, Adam J. "Studies toward a prebiotic protometabolism." Thesis, University College London (University of London), 2017. http://discovery.ucl.ac.uk/10038454/.

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Understanding the origin of life is one of the foremost challenges for science. Despite the immense diversity displayed by biology on the macroscopic scale, cellular biochemistry is at its most fundamental level remarkably uniform. Recognising the minimal elements of biochemistry required for a living system represents one task within origins of life research, whereas the other is understanding the organic chemistry which could have led to their spontaneous organisation on the abiotic Earth. Significant attention has been paid to the prebiotic generation and assembly of the components of nucle
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Ajram, Ghinwa. "Energetic processes driving potential peptide protometabolisms at the origin of living systems." Thesis, Montpellier, 2018. http://www.theses.fr/2018MONTS119/document.

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La thèse aborde différentes questions de chimie prébiotique dans le contexte de l’origine de la vie par une approche de chimie systémique. La première partie est dédiée à l’étude de processus d’activation chimique important non seulement pour la formation de polymères, mais aussi pour alimenter le système en énergie de manière à le maintenir dans un état éloigné de l’équilibre, un prérequis pour l’auto-organisation. Il a été suggéré que les intermédiaires 5(4H)-oxazolones formés par l’activation de l’extrémité C-terminale des peptides pourrait être impliquée dans l’auto-organisation du vivant.
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Ter-Ovanessian, Louis. "Apparition d'un métabolisme primitif dans les scénarios géochimiques d'origine de la vie. Avant le monde ARN." Electronic Thesis or Diss., Sorbonne université, 2022. http://www.theses.fr/2022SORUS377.

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Un scénario incontournable aux origines de la vie est celui du « monde ARN ». Pour le valider, il est nécessaire d’expliquer comment les premières molécules d’ARN se sont formées à partir de précurseurs moléculaires plus simples. Reste à savoir si les nucléobases non canoniques ont été formées parallèlement aux canoniques ou plus tard, lorsque la vie a nécessité une plus grande diversité fonctionnelle. Notre hypothèse est que les voies métaboliques modernes pourraient être en partie héritées des réseaux de réactions abiotiques, compatibles avec le contexte géochimique. Ces réseaux seraient le
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Book chapters on the topic "Protometabolism"

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Flügel, Rolf M. "The Iron Sulfide World of Protometabolism." In Chirality and Life. Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-16977-9_13.

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"Protometabolism." In Singularities. Cambridge University Press, 2005. http://dx.doi.org/10.1017/cbo9780511614736.006.

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"Protometabolism Revisited." In Singularities. Cambridge University Press, 2005. http://dx.doi.org/10.1017/cbo9780511614736.015.

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