Academic literature on the topic 'Proton beam radiotherapy'

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Journal articles on the topic "Proton beam radiotherapy"

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Jones, B., and R. D. Errington. "Proton beam radiotherapy." British Journal of Radiology 73, no. 872 (2000): 802–5. http://dx.doi.org/10.1259/bjr.73.872.11026853.

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Raldow, Ann, James Lamb, and Theodore Hong. "Proton beam therapy for tumors of the upper abdomen." British Journal of Radiology 93, no. 1107 (2020): 20190226. http://dx.doi.org/10.1259/bjr.20190226.

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Proton radiotherapy has clear dosimetric advantages over photon radiotherapy. In contrast to photons, which are absorbed exponentially, protons have a finite range dependent on the initial proton energy. Protons therefore do not deposit dose beyond the tumor, resulting in great conformality, and offers the promise of dose escalation to increase tumor control while minimizing toxicity. In this review, we discuss the rationale for using proton radiotherapy in the treatment of upper abdominal tumors—hepatocellular carcinomas, cholangiocarcinomas and pancreatic cancers. We also review the clinical
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Fukumitsu, Nobuyoshi. "Particle Beam Therapy for Cancer of the Skull Base, Nasal Cavity, and Paranasal Sinus." ISRN Otolaryngology 2012 (May 31, 2012): 1–6. http://dx.doi.org/10.5402/2012/965204.

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Particle beam therapy has been rapidly developed in these several decades. Proton and carbon ion beams are most frequently used in particle beam therapy. Proton and carbon ion beam radiotherapy have physical and biological advantage to the conventional photon radiotherapy. Cancers of the skull base, nasal cavity, and paranasal sinus are rare; however these diseases can receive the benefits of particle beam radiotherapy. This paper describes the clinical review of the cancer of the skull base, nasal cavity, and paranasal sinus treated with proton and carbon ion beams, adding some information of
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Barker, Claire, Matthew Lowe, and Ganesh Radhakrishna. "An introduction to proton beam therapy." British Journal of Hospital Medicine 80, no. 10 (2019): 574–78. http://dx.doi.org/10.12968/hmed.2019.80.10.574.

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Radiotherapy is a highly effective anti-cancer treatment commonly used alongside systemic therapies and surgery to achieve long-term cancer-free survival. Conventional radiotherapy uses photon beams to deliver a high dose of radiation to the tumour volume to eradicate cancer cells. This has to be offset against the irradiation of surrounding normal tissues, as increasing this dose causes more treatment-related toxicity. In August 2018, the NHS's first high energy proton beam therapy centre opened at The Christie NHS Foundation Trust in Manchester. A second NHS centre is scheduled to open in 20
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Chen, Clark C., Jay S. Loeffler, and Paul H. Chapman. "Proton Beam Radiosurgery and Radiotherapy." Techniques in Neurosurgery 9, no. 3 (2003): 218–25. http://dx.doi.org/10.1097/00127927-200309030-00014.

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Nahum, A. E., D. P. Dearnaley, and G. G. Steel. "Prospects for proton-beam radiotherapy." European Journal of Cancer 30, no. 10 (1994): 1577–83. http://dx.doi.org/10.1016/0959-8049(94)00316-w.

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Hughes, Jonathan R., and Jason L. Parsons. "FLASH Radiotherapy: Current Knowledge and Future Insights Using Proton-Beam Therapy." International Journal of Molecular Sciences 21, no. 18 (2020): 6492. http://dx.doi.org/10.3390/ijms21186492.

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FLASH radiotherapy is the delivery of ultra-high dose rate radiation several orders of magnitude higher than what is currently used in conventional clinical radiotherapy, and has the potential to revolutionize the future of cancer treatment. FLASH radiotherapy induces a phenomenon known as the FLASH effect, whereby the ultra-high dose rate radiation reduces the normal tissue toxicities commonly associated with conventional radiotherapy, while still maintaining local tumor control. The underlying mechanism(s) responsible for the FLASH effect are yet to be fully elucidated, but a prominent role
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Fix, Michael K., and Peter Manser. "Treatment planning aspects and Monte Carlo methods in proton therapy." Modern Physics Letters A 30, no. 17 (2015): 1540022. http://dx.doi.org/10.1142/s0217732315400222.

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Over the last years, the interest in proton radiotherapy is rapidly increasing. Protons provide superior physical properties compared with conventional radiotherapy using photons. These properties result in depth dose curves with a large dose peak at the end of the proton track and the finite proton range allows sparing the distally located healthy tissue. These properties offer an increased flexibility in proton radiotherapy, but also increase the demand in accurate dose estimations. To carry out accurate dose calculations, first an accurate and detailed characterization of the physical proto
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Daw, Najat C., and Anita Mahajan. "Photons or Protons for Non–Central Nervous System Solid Malignancies in Children: A Historical Perspective and Important Highlights." American Society of Clinical Oncology Educational Book, no. 33 (May 2013): e354-e359. http://dx.doi.org/10.14694/edbook_am.2013.33.e354.

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Over the years, major advances have occurred in radiotherapy techniques, delivery, and treatment planning. Although radiotherapy is an integral treatment component of pediatric solid tumors, it is associated with potential acute and long-term untoward effects and risk of secondary malignancy particularly in growing children. Two major advances in external beam radiotherapy are intensity-modulated radiotherapy (IMRT) and proton beam radiotherapy. Their use in the treatment of children with cancer has been steadily increasing. IMRT uses multiple modulated radiation fields that enhance the confor
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Rutenberg, Michael S., and Romaine C. Nichols. "Proton beam radiotherapy for pancreas cancer." Journal of Gastrointestinal Oncology 11, no. 1 (2020): 166–75. http://dx.doi.org/10.21037/jgo.2019.03.02.

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Dissertations / Theses on the topic "Proton beam radiotherapy"

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Howarth, Ashley L., Joshua R. Niska, Kenneth Brooks, et al. "Tissue Expanders and Proton Beam Radiotherapy." LIPPINCOTT WILLIAMS & WILKINS, 2017. http://hdl.handle.net/10150/625389.

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Proton beam radiotherapy (PBR) has gained acceptance for the treatment of breast cancer because of unique beam characteristics that allow superior dose distributions with optimal dose to the target and limited collateral damage to adjacent normal tissue, especially to the heart and lungs. To determine the compatibility of breast tissue expanders (TEs) with PBR, we evaluated the structural and dosimetric properties of 2 ex vivo models: 1 model with internal struts and another model without an internal structure. Although the struts appeared to have minimal impact, we found that the metal TE por
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Handley, Stephen Michael. "Monte Carlo simulations using MCNPX of proton and anti-proton beam profiles for radiation therapy." Oklahoma City : [s.n.], 2010.

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Warren, Daniel Rosevear. "Proton radiotherapy uncertainties arising from computed tomography." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:ab59f596-e277-490a-a7c1-1cb81b47b9a9.

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Proton radiotherapy is a cancer treatment which has the potential to offer greater cure rates and/or fewer serious side effects than conventional radiotherapy. Its availability in the UK is currently limited to a single low-energy fixed beamline for the treatment of ocular tumours, but a number of facilities designed to treat deep-seated tumours are in development. This thesis focusses on the quantitative use of x-ray computed tomography (CT) images in planning proton radiotherapy treatments. It arrives at several recommendations that can be used to inform clinical protocols for the acquisitio
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Parodi, Katia. "On the feasibility of dose quantification with in-beam PET data in radiotherapy with 12C and proton beams." Forschungszentrum Dresden, 2010. http://nbn-resolving.de/urn:nbn:de:bsz:d120-qucosa-28788.

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This thesis has contributed to the achievement of in-beam PET as a promising clinical monitoring technique. In response to a pressing medical demand, this work has provided a tool for quantification of local dose deviations in case of observed discrepancies between the measured and expected PET images. The implemented interactive approach described in chapter 3 is in clinical use since 2001. It provides the radio-oncologist with a valuable feedback which may allow a prompt reaction in the strategy of the therapy prior to the delivery of the successive treatment fraction in case of signi
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Parodi, Katia. "On the feasibility of dose quantification with in-beam PET data in radiotherapy with 12C and proton beams." Rossendorf : Forschungszentrum, 2004. http://www.fz-rossendorf.de/publications/006865/6865.pdf.

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da, Silva Joakim. "Pencil beam dose calculation for proton therapy on graphics processing units." Thesis, University of Cambridge, 2016. https://www.repository.cam.ac.uk/handle/1810/254300.

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Radiotherapy delivered using scanned beams of protons enables greater conformity between the dose distribution and the tumour than conventional radiotherapy using X rays. However, the dose distributions are more sensitive to changes in patient anatomy, and tend to deteriorate in the presence of motion. Online dose calculation during treatment delivery offers a way of monitoring the delivered dose in real time, and could be used as a basis for mitigating the effects of motion. The aim of this work has therefore been to investigate how the computational power offered by graphics processing units
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Mondlane, Gracinda. "Comparative study of Radiation Therapy of Targets in the Upper Abdomen with Photon- or Scanned Proton-beams." Licentiate thesis, Stockholms universitet, Fysikum, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-144550.

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Recently, there has been an increase in the number of proton beam therapy (PBT) centers operating worldwide. For certain cases, proton beams have been shown to provide dosimetric and radiobiological advantages when used for cancer treatment, compared to the regular photon-beam based treatments. Under ideal circumstances, the dose given to the tissues surrounding a target can be reduced with PBT. The risk for side effects following treatment is then expected to decrease. Until present, mainly stationary targets, e.g. targets in the brain, have been treated with PBT. There is currently a growing
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Ts`oeu, M. S. "Proton beam steering control system for high precision radiotherapy at iThemba LABS : an investigation on actuator saturation constraints." Master's thesis, University of Cape Town, 2008. http://hdl.handle.net/11427/5095.

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Includes abstract.<br>Includes bibliographical references (leaves 101-106).<br>This thesis aims at studying some of the techniques used to deal with constraints with special application to the Proton beam steering control at iThemba LABS. The steering of charged particles occurring in research plants is one of the interests of control systems. In this work an investigation of the algorithm for the control of the proton beam steering system in the radiotherapy treatment facility at iThemba LABS is conducted. This algorithm is intended to autonomously maintain the beam centered with reference to
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Masood, Umar. "Radiotherapy Beamline Design for Laser-driven Proton Beams." Helmholtz Zentrum Dresden Rossendorf, 2018. https://tud.qucosa.de/id/qucosa%3A35640.

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Motivation: Radiotherapy is an important modality in cancer treatment commonly using photon beams from compact electron linear accelerators. However, due to the inverse depth dose profile (Bragg peak) with maximum dose deposition at the end of their path, proton beams allow a dose escalation within the target volume and reduction in surrounding normal tissue. Up to 20% of all radiotherapy patients could benefit from proton therapy (PT). Conventional accelerators are utilized to obtain proton beams with therapeutic energies of 70 – 250 MeV. These beams are then transported to the patient via ma
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Sjögren, Adam. "The impact of metallic cranial implants on proton-beam radiotherapy treatment plans for near implant located tumours : A phantom study on the physical effects and agreement between simulated treatment plans and the resulting treatment for near implant located cranial tumours." Thesis, Umeå universitet, Institutionen för fysik, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-149530.

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Within the field of radiotherapy treatments of tumour diseases, the hunt for more accurate and effective treatment methods is a continuous process. For some years ion-beam based radiotherapy, especially the proton-beam based applications, has increased in popularity and availability. The main reason behind this is the fact that ion-beam based applications make it possible to modulate the dose after the planning target volume (PTV) defined by the radiation oncologist. This means that it becomes possible to spare tissue in another way, which might result in more effective treatments, especially
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Books on the topic "Proton beam radiotherapy"

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Tsuboi, Koji, Takeji Sakae, and Ariungerel Gerelchuluun, eds. Proton Beam Radiotherapy. Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-13-7454-8.

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Proton therapy physics. Taylor & Francis, 2012.

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Tsuboi, Koji, Takeji Sakae, and Ariungerel Gerelchuluun. Proton Beam Radiotherapy: Physics and Biology. Springer, 2020.

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Yajnik, Santosh. Proton Beam Therapy: How Protons are Revolutionizing Cancer Treatment. Springer, 2012.

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Yajnik, Santosh. Proton Beam Therapy: How Protons are Revolutionizing Cancer Treatment. Springer, 2012.

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Yajnik, Santosh. Proton Beam Therapy: How Protons are Revolutionizing Cancer Treatment. Springer, 2014.

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Boterberg, Tom, Karin Dieckmann, and Mark Gaze, eds. Radiotherapy and the Cancers of Children, Teenagers, and Young Adults. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198793076.001.0001.

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As most cancers occur in middle-aged or older adults, only a very small proportion of the overall radiotherapy workload relates to children and young people. As there is a wide spectrum of different cancer types in this age group, not only is paediatric cancer uncommon overall but each individual type is very rare. There are many ways in which to deliver radiotherapy, including advanced photon techniques, proton beam therapy, brachytherapy, and molecular radiotherapy. For these reasons, the care of children and young people requiring radiotherapy is limited to a small number of highly speciali
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(Editor), Thomas F. DeLaney, and Hanne M. Kooy (Editor), eds. Proton and Charged Particle Radiotherapy. Lippincott Williams & Wilkins, 2007.

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F, De Laney Thomas, and Kooy Hanne M, eds. Proton and charged particle radiotherapy. Wolters Kluwer Health/Lippincott Williams & Wilkins, 2008.

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F, De Laney Thomas, and Kooy Hanne M, eds. Proton and charged particle radiotherapy. Wolters Kluwer Health/Lippincott Williams & Wilkins, 2008.

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Book chapters on the topic "Proton beam radiotherapy"

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Cohen, Victoria M. L., and Arun D. Singh. "Proton Beam Radiotherapy." In Pocket Guide to Ocular Oncology and Pathology. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-29782-3_68.

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Yasuoka, Kiyoshi. "Dosimetry of Proton Beams." In Proton Beam Radiotherapy. Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-13-7454-8_5.

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Tsuboi, Koji. "Current Topics of Proton Radiobiology." In Proton Beam Radiotherapy. Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-13-7454-8_13.

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Takei, Hideyuki. "Physical Characteristics of Proton Beams." In Proton Beam Radiotherapy. Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-13-7454-8_4.

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Kumada, Hiroaki. "Accelerator Systems for Proton Radiotherapy." In Proton Beam Radiotherapy. Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-13-7454-8_8.

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Mori, Yutaro, Takeji Sakae, Kenta Takada, and Hideyuki Takei. "Treatment Planning System for Proton Radiotherapy." In Proton Beam Radiotherapy. Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-13-7454-8_10.

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Kamizawa, Satoshi. "Quality Assurance for Proton Beam Radiotherapy." In Proton Beam Radiotherapy. Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-13-7454-8_12.

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Kumada, Hiroaki. "Beam Delivery System for Proton Radiotherapy." In Proton Beam Radiotherapy. Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-13-7454-8_9.

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Yasuoka, Kiyoshi. "Discovery of the Proton and Its Intrinsic Powers." In Proton Beam Radiotherapy. Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-13-7454-8_1.

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Terunuma, Toshiyuki. "Motion Management." In Proton Beam Radiotherapy. Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-13-7454-8_11.

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Conference papers on the topic "Proton beam radiotherapy"

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de Melo Re^go, Maria Euge^nia, B. V. Carlson, Valdir Guimaraes, José R. B. Oliveira, Kita C. D. Macario, and Frederico A. Genezini. "Nuclear Data for Proton Beam Radiotherapy." In NUCLEAR PHYSICS 2008: XXXI Workshop on Nuclear Physics in Brazil. AIP, 2009. http://dx.doi.org/10.1063/1.3157813.

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Chen, Ning, Lu Jiang, Jianliang Zhou, and Xiaoping Qiu. "Comparison of Proton Beam and Photons Beam in the Radiotherapy of NPC." In 2015 7th International Conference on Information Technology in Medicine and Education (ITME). IEEE, 2015. http://dx.doi.org/10.1109/itme.2015.37.

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Boudinet, M., J. Y. Le Huerou, P. Laugier, O. Berges, L. Lumbroso-Lerouic, and L. Desjardins. "P6C-3 Quantitative Ultrasonography Of Choroidal Melanoma Following Proton-Beam Radiotherapy." In 2007 IEEE Ultrasonics Symposium. IEEE, 2007. http://dx.doi.org/10.1109/ultsym.2007.623.

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Chernykh, Aleksey Nikolaevich. "DESIGN AND KINEMATIC ANALYSIS OF A ROBOTIZED CHAIR FOR PROTON ADIATION THERAPY." In International conference New technologies in medicine, biology, pharmacology and ecology (NT +M&Ec ' 2020). Institute of information technology, 2020. http://dx.doi.org/10.47501/978-5-6044060-0-7.05.

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Proton radiotherapy becomes increasingly important in external radiotherapy. In particular, proton beam&#x0D; radiation therapy is the most successful and almost non-alternative method of radiation treatment of patients&#x0D; with intraocular malignant neoplasms. However, currently, the chairs for positioning patients during proton&#x0D; radiation therapy in the treatment rooms using the fixed proton beam direction do not have the functions of&#x0D; positioning the fixed head and neck. This article presents a new design of a chair for proton radiation therapy&#x0D; with a head and neck positio
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Dabrowska, Joanna, Pawel Olko, Urszula Sowa, and Jan Swakon. "Optimization of Beam Scattering System for IFJ PAN Proton Radiotherapy Facility by Monte Carlo Simulations." In 2008 IEEE Nuclear Science Symposium and Medical Imaging conference (2008 NSS/MIC). IEEE, 2008. http://dx.doi.org/10.1109/nssmic.2008.4774584.

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Zhao, Li, George Sandison, Jonathan Farr, Huanmei Wu, and Markus Fitzek. "The Moving Target Induced Dosimetric Effect vs. Beam Direction in Proton Radiotherapy of Moving Lung Tumors." In 2008 International Conference on Biomedical Engineering And Informatics (BMEI). IEEE, 2008. http://dx.doi.org/10.1109/bmei.2008.317.

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Murakami, Masao, Yusuke Demizu, Yasue Niwa, et al. "Current State Of Proton And Carbon-Ion Radiotherapy At The Hyogo Ion Beam Medical Center (HIBMC)." In APPLICATION OF ACCELERATORS IN RESEARCH AND INDUSTRY: Twenty-First International Conference. AIP, 2011. http://dx.doi.org/10.1063/1.3586123.

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Crawford, Kayva L., Arvin R. Wali, Adam S. DeConde, and Thomas L. Beaumont. "Bilateral Inferior Turbinate Flap for Repair of Skull Base Dehiscence after Proton Beam Radiotherapy for Clival Chordoma." In Special Virtual Symposium of the North American Skull Base Society. Georg Thieme Verlag KG, 2021. http://dx.doi.org/10.1055/s-0041-1725532.

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Krummel, Daniel Pomeranz, Laura Kallay, Debanjan Bhattacharya, et al. "Abstract PO-009: Targeting a unique electrochemical vulnerability in a pediatric brain tumor to potentiate proton beam radiotherapy." In Abstracts: AACR Virtual Special Conference on Radiation Science and Medicine; March 2-3, 2021. American Association for Cancer Research, 2021. http://dx.doi.org/10.1158/1557-3265.radsci21-po-009.

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Verma, Sneha K., Brent J. Liu, Daila S. Gridley, Xiao W. Mao, and Nikhil Kotha. "An imaging informatics-based system to support animal studies for treating pain in spinal cord injury utilizing proton-beam radiotherapy." In SPIE Medical Imaging, edited by Tessa S. Cook and Jianguo Zhang. SPIE, 2015. http://dx.doi.org/10.1117/12.2081550.

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