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1

H, Thomas Ralph. Radiological safety aspects of the operation of proton accelerators. Vienna: International Atomic Energy Agency, 1988.

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2

Keegan, Raymond P. LET spectrum generation and proton induced secondary contribution to total dose measured in low earth orbit. Dublin: University College Dublin, 1996.

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3

Galand, Marina. Radiation damage of the proton MEPED detector on POES (TIROS/NOAA) satellites. Silver Spring, MD: U.S. Dept. of Commerce, National Oceanic and Atmospheric Administration, Space Environment Center, 2000.

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4

Becher, Jacob. The simulated space proton environment for radiation effects on Space Telescope Imaging Spectrograph (STIS). Norfolk, Va: Old Dominion University Research Foundation, 1992.

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5

Weinberg, Irving. Performance and temperature dependencies of proton irradiated n/p and p/n GaAs and n/p silicon cells. [Washington, DC]: National Aeronautics and Space Administration, 1985.

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6

Huston, S. L. Space environment effects: Low-altitude trapped radiation model. [Marshall Space Flight Center], Ala: National Aeronautics and Space Administration, Marshall Space Flight Center, 1998.

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7

Weinberg, Irving. Effects of electron and proton irradiations on n/p and p/n GaAs cells grown by MOCVD. [Washington, D.C.]: National Aeronautics and Space Administration, 1987.

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8

Weinberg, Irving. Potential for use of Indium phosphide solar cells in the space radiation environment. [Cleveland, Ohio: National Aeronautics and Space Administration, Lewis Research Center, 1985.

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9

Prague, Czech Republic) SPIE Optics +. Optoelectronics (2011. Laser acceleration of electrons, protons, and ions: And medical applications of laser-generated secondary sources of radiation and particles : 18-20 April 2011, Prague, Czech Republic. Bellingham, Washington: SPIE, 2011.

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10

International Commission on Radiation Units and Measurements., ed. Clinical proton dosimetry. Bethesda, Md: International Commission on Radiation Units and Measurements, 1998.

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11

International Commission on Radiation Units and Measurements., ed. Photon, electron, proton, and neutron interaction data for body tissues. Bethesda, Md., U.S.A: International Commission on Radiation Units and Measurements, 1992.

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12

C, Simonsen Lisa, and United States. National Aeronautics and Space Administration. Scientific and Technical Information Program., eds. Radiation dose to critical body organs for October 1989 proton event. [Washington, DC]: National Aeronautics and Space Administration, Office of Management, Scientific and Technical Information Program, 1992.

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13

C, Simonsen Lisa, and United States. National Aeronautics and Space Administration. Scientific and Technical Information Program., eds. Radiation dose to critical body organs for October 1989 proton event. [Washington, DC]: National Aeronautics and Space Administration, Office of Management, Scientific and Technical Information Program, 1992.

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14

Taylor, Roger E. Principles of paediatric radiation oncology. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199696567.003.0020.

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Chapter 15 discusses the principles of paediatric radiation oncology, and addresses quality assurance, chemotherapy/radiotherapy interactions, Leukaemia, Hodgkin lymphoma, Non-Hodgkin lymphoma, Neuroblastoma, Rhabdomyosarcoma, Ewing’s sarcoma/peripheral primitive neuroectodermal tumour, Osteosarcoma, central nervous system tumours, Intensity-modulated radiotherapy, and proton therapy for paediatric tumours.
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15

Mars surface radiation exposure for solar maximum conditions and 1989 solar proton events. [Washington, DC]: National Aeronautics and Space Administration, Office of Management, Scientific and Technical Information Program, 1993.

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16

Deruelle, Nathalie, and Jean-Philippe Uzan. Radiation by a charge. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198786399.003.0036.

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This chapter takes a look at the energy radiated by a single charge. After deriving the Larmor formulas, it studies the paradigmatic cases of the radiation of a linearly accelerated charge. Next, it turns to the synchrotron radiation of a charge in circular motion. Finally, the chapter considers the radiation of a charge accelerated by an electromagnetic wave—Thomson scattering, which is when the energy is radiated to infinity. In addition, the chapter also reveals that the hydrogen atom as described by the Rutherford model of an electron orbiting a proton is highly unstable in Maxwell theory.
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17

International Commission On Radiation Un. Nuclear Data for Neutron and Proton Radiotherapy and for Radiation Protection: Icru Report 63 (International Commission on Radiation Units and Measurements//I C R U Report). International Commission, 2000.

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18

Jet Propulsion Laboratory (U.S.), ed. Characterization of production GaAs solar cells for space. Pasadena, Calif: National Aeronautics and Space Administration, Jet Propulsion Laboratory, California Institute of Technology, 1988.

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19

A, Xapsos M., and George C. Marshall Space Flight Center., eds. Space environment effects: Model for emission of solar protons (ESP)--cumulative and worst-case event fluences. [Marshall Space Flight Center], Ala: National Aeronautics and Space Administration, Marshall Space Flight Center, 1999.

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20

Boterberg, Tom, Karin Dieckmann, and Mark Gaze, eds. Radiotherapy and the Cancers of Children, Teenagers, and Young Adults. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198793076.001.0001.

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As most cancers occur in middle-aged or older adults, only a very small proportion of the overall radiotherapy workload relates to children and young people. As there is a wide spectrum of different cancer types in this age group, not only is paediatric cancer uncommon overall but each individual type is very rare. There are many ways in which to deliver radiotherapy, including advanced photon techniques, proton beam therapy, brachytherapy, and molecular radiotherapy. For these reasons, the care of children and young people requiring radiotherapy is limited to a small number of highly specialist centres. Delivery of high-quality paediatric radiotherapy requires a multiprofessional team including radiation or clinical oncologists, therapy radiographers, physicists, dosimetrists, anaesthetists, and play specialists. This team has to interact very closely with the wider paediatric and adolescent oncology multidisciplinary team, which includes oncologists, surgeons with different anatomical expertise, radiologists, and pathologists. Children, with their developing tissues and organs, are more susceptible to long-term radiation-induced complications, including second cancers, than adults. The art of paediatric radiotherapy, therefore, is to select treatment approaches which offer the maximum chance of cure while minimizing the risk of adverse effects. Careful teamwork, peer review of radiotherapy planning, and quality assurance within a clinical trial framework offer the best chances of achieving this balance. This book covers all these aspects, highlighting the need for highly specialist teams with the extensive knowledge and the broad skillset required to offer children and young people the best possible treatments.
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21

Solid state radiation dosimeters for space and medical applications. Pasadena, Calif: National Aeronautics and Space Administration, Jet Propulsion Laboratory, California Institute of Technology, 1996.

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22

1946-, Kühn J. H., ed. Radiative corrections for e+e- collisions: Proceedings of the international workshop held at Schloss Ringberg, Tegernsee, FRG, April 3-7, 1989. Berlin: Springer-Verlag, 1989.

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23

Kuhn, Jens H. Radiative Corrections for E+E- Collisions: Proceedings of the International Workshop Held at Schlob Ringberg Tegernsee, Frg, April 3-7, 1989. Springer, 1989.

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24

L, Kernell R., Reft Chester, Old Dominion University. Dept. of Physics., and Goddard Space Flight Center, eds. Radiation effects induced in pin photodiodes by 40- and 85-MeV protons: Progress report for the period ending January 31, 1985. Norfolk, Va: Old Dominion University Research Foundation, 1985.

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25

Schroeder, Kristin, and Oren Becher. Pontine Gliomas. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0138.

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Pontine gliomas-also known as diffuse intrinsic pontine gliomas (DIPG)-primarily occur in children and typically present subacutely with a combination of cranial nerve palsies associated with long track signs including hyper-reflexia in the legs, positive Babinski responses, and cerebellar signs. On imaging they typically appear as intrinsic mass lesions within the pons. Treatment with radiation can prolong the course of from months to years but the tumors are rarely curable. Chemotherapy combined with radiation therapy targeted at specific signaling pathways has shown only modest impact on survival.
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26

S, Bratoli͡u︡bova-T͡S︡ulukidze L., and Akademii͡a︡ nauk SSSR. Mezhduvedomstvennyĭ geofizicheskiĭ komitet., eds. Srednechasovye skorosti scheta st͡s︡intilli͡a︡t͡s︡ionno-cherenkovskogo detektora v mezhplanetnom prostranstve po dannym sputnika "Prognoz-7": Dannye nabli͡u︡deniĭ 31 okti͡a︡bri͡a︡ 1978-12 ii͡u︡ni͡a︡ 1979. Moskva: Mezhduvedomstvennyĭ geofizicheskiĭ kom-t pri Prezidiume AN SSSR, 1989.

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27

A Lyman-alpha tunable acousto-optic filter for detecting superthermal flare protons: Final technical report. [Washington, DC]: National Aeronautics and Space Administration, 1994.

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28

United States. National Aeronautics and Space Administration., ed. A Lyman-alpha tunable acousto-optic filter for detecting superthermal flare protons: Final technical report. [Washington, DC]: National Aeronautics and Space Administration, 1994.

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29

United States. National Aeronautics and Space Administration., ed. A Lyman-alpha tunable acousto-optic filter for detecting superthermal flare protons: Final technical report. [Washington, DC]: National Aeronautics and Space Administration, 1994.

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30

Ellam, Rob. 5. Physics heal thyself. Oxford University Press, 2016. http://dx.doi.org/10.1093/actrade/9780198723622.003.0005.

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Stable and radioactive isotopes are used extensively in diagnostic and therapeutic medical applications including studies of human body composition, energy balance, protein turnover, and metabolism. ‘Physics heal thyself: isotopes in medicine’ shows how ionizing radiation is key to a host of medical imaging techniques with radioactive isotopes widely used to target and kill cancer cells. Enriched isotopes are used as biological tracers; doubly labelled water in the diagnosis of type 2 diabetes; and 13C-labelled urea in diagnosing stomach and duodenal ulcers. Medical uses of ionizing radiation are manifold including X-ray imaging, radiotherapy with external X-ray beams, brachytherapy, targeted radionuclide therapy, single photon emission computed tomography, and positron emission tomography.
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31

Receiver design, performance analysis, and evaluation for space-borne laser altimeters and space-to-space laser ranging systems: Interim progress report on NASA grant NAG5-2232 ... for the period of April 15, 1996 to Oct. 14, 1996. [Washington, DC: National Aeronautics and Space Administration, 1996.

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32

Sun, Xiaoli, Field Christopher T, and United States. National Aeronautics and Space Administration., eds. "Receiver design, performance analysis, and evaluation for space-borne laser altimeters and space-to-space laser ranging systems": Interim progress report on NASA grant NAG5-2232 : for the period of April 15, 1994 to October 15, 1994. [Baltimore, Md.]: the Johns Hopkins University, Electrical & Computer Engineering, 1994.

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33

Sun, Xiaoli, Field Christopher T, and United States. National Aeronautics and Space Administration., eds. "Receiver design, performance analysis, and evaluation for space-borne laser altimeters and space-to-space laser ranging systems": Interim progress report on NASA grant NAG5-2232 : for the period of October 16, 1994 to April 15, 1995. [Baltimore, Md.]: Johns Hopkins University, Electrical & Computer Engineering, 1995.

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34

Bensimon, David, Vincent Croquette, Jean-François Allemand, Xavier Michalet, and Terence Strick. Single-Molecule Studies of Nucleic Acids and Their Proteins. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198530923.001.0001.

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This book presents a comprehensive overview of the foundations of single-molecule studies, based on manipulation of the molecules and observation of these with fluorescent probes. It first discusses the forces present at the single-molecule scale, the methods to manipulate them, and their pros and cons. It goes on to present an introduction to single-molecule fluorescent studies based on a quantum description of absorption and emission of radiation due to Einstein. Various considerations in the study of single molecules are introduced (including signal to noise, non-radiative decay, triplet states, etc.) and some novel super-resolution methods are sketched. The elastic and dynamic properties of polymers, their relation to experiments on DNA and RNA, and the structural transitions observed in those molecules upon stretching, twisting, and unzipping are presented. The use of these single-molecule approaches for the investigation of DNA–protein interactions is highlighted via the study of DNA and RNA polymerases, helicases, and topoisomerases. Beyond the confirmation of expected mechanisms (e.g., the relaxation of DNA torsion by topoisomerases in quantized steps) and the discovery of unexpected ones (e.g., strand-switching by helicases, DNA scrunching by RNA polymerases, and chiral discrimination by bacterial topoII), these approaches have also fostered novel (third generation) sequencing technologies.
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35

Deruelle, Nathalie, and Jean-Philippe Uzan. The two-body problem and radiative losses. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198786399.003.0055.

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This chapter begins by finding the field created by compact objects in the post-linear approximation of general relativity. The second quadrupole formula is then completely proven. Next, the chapter finds the equations of motion of the bodies in the field which they create to second order in the perturbations, assuming that their velocities are small. It shows that, to correctly describe the radiation reaction at 2.5 PN order, it will prove necessary to iterate Einstein equations a third time. This leads the discussion to the equations of motion, which generalize to order 1/c5 the EIH equations of order 1/c⁲. Finally, the chapter studies the effect of the radiation reaction force on the sources, and shows that there is an energy balance at 2.5 PN order between the energy radiated to infinity and the mechanical energy lost by the system.
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36

Cohen, Aly. Proactive Approaches to Reduce Environmental Exposures. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190490911.003.0014.

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This chapter gives healthcare providers recommendations and tools to help patients mitigate exposure to harmful environmental chemicals, radiation, and other stressors; limiting contact and maximizing innate biological detoxification pathways through the safe use of exercise, diet, and appropriate supplements. Of particular concern are the vulnerable periods of biological development, when harmful chemicals can have the most deleterious effects. Therefore, particular attention is paid to the care of young children and pregnant women. Whether chemical exposure comes from food additives and food packaging, water, personal care and cleaning products, air contamination, or radiation, this chapter gives clear, practical, and safe recommendations for chemical reduction and embraces the precautionary principle when there is evidence of harm, but proof of causality, a very high standard, has not been established. The current approach of only regulating products after there is certainty of human harm has failed to protect the public health.
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37

Sedel, Frédéric. Krabbe Disease in Adults. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199972135.003.0051.

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Krabbe disease (globoid cell leukodystrophy) is an autosomal recessive lysosomal storage disease caused by mutations in the lysosomal galactocerebrosidase (galactosyl ceramidase) gene. Krabbe disease usually presents as a severe leukodystrophy in early infancy and childhood. In contrast, adult patients usually present with progressive spastic paraparesis. Other signs of the disease include peripheral neuropathy, dysarthria, cerebellar ataxia, pes cavus deep sensory signs, tongue atrophy, optic neuropathy, cognitive decline. Cerebrospinal fluid protein concentration is moderately increased in adults. High signals of cortico-spinal tracts on brain MRI are highly suggestive and this typical aspect may be associated with hyper-intensities of optic radiations, and of the posterior part of the corpus callosum.
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38

Center, NASA Glenn Research, ed. Effect of voltage level on power system design for solar electric propulsion missions. [Cleveland, Ohio]: National Aeronautics and Space Administration, Glenn Research Center, 2003.

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39

Center, NASA Glenn Research, ed. Effect of voltage level on power system design for solar electric propulsion missions. [Cleveland, Ohio]: National Aeronautics and Space Administration, Glenn Research Center, 2003.

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40

Cohadon, Pierre-François, Jack Harris, Florian Marquardt, and Leticia Cugliandolo, eds. Quantum Optomechanics and Nanomechanics. Oxford University Press, 2020. http://dx.doi.org/10.1093/oso/9780198828143.001.0001.

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The Les Houches Summer School 2015 covered the emerging fields of cavity optomechanics and quantum nanomechanics. Optomechanics is flourishing and its concepts and techniques are now applied to a wide range of topics. Modern quantum optomechanics was born in the late 70s in the framework of gravitational wave interferometry, initially focusing on the quantum limits of displacement measurements. Carlton Caves, Vladimir Braginsky, and others realized that the sensitivity of the anticipated large-scale gravitational-wave interferometers (GWI) was fundamentally limited by the quantum fluctuations of the measurement laser beam. After tremendous experimental progress, the sensitivity of the upcoming next generation of GWI will effectively be limited by quantum noise. In this way, quantum-optomechanical effects will directly affect the operation of what is arguably the world’s most impressive precision experiment. However, optomechanics has also gained a life of its own with a focus on the quantum aspects of moving mirrors. Laser light can be used to cool mechanical resonators well below the temperature of their environment. After proof-of-principle demonstrations of this cooling in 2006, a number of systems were used as the field gradually merged with its condensed matter cousin (nanomechanical systems) to try to reach the mechanical quantum ground state, eventually demonstrated in 2010 by pure cryogenic techniques and a year later by a combination of cryogenic and radiation-pressure cooling. The book covers all aspects—historical, theoretical, experimental—of the field, with its applications to quantum measurement, foundations of quantum mechanics and quantum information. Essential reading for any researcher in the field.
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