Relevant bibliographies by topics / Proton therapy, PET, FLUKA, treatment monitoring

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  1. Journal articles
  2. Dissertations / Theses

Academic literature on the topic 'Proton therapy, PET, FLUKA, treatment monitoring'

Author: Grafiati
Published: 14 March 2023
Last updated: 31 July 2025

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Journal articles on the topic "Proton therapy, PET, FLUKA, treatment monitoring"

1

Moglioni, M., A. C. Kraan, A. Berti, et al. "Analysis methods for in-beam PET images in proton therapy treatment verification: a comparison based on Monte Carlo simulations." Journal of Instrumentation 18, no. 01 (2023): C01001. http://dx.doi.org/10.1088/1748-0221/18/01/c01001.

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Abstract Background and purpose: in-beam Positron Emission Tomography (PET) is one of the modalities that can be used for in-vivo non-invasive treatment monitoring in proton therapy. PET distributions obtained during various treatment sessions can be compared in order to identify regions that have anatomical changes. The purpose of this work is to test and compare different analysis methods in the context of inter-fractional PET image comparison for proton treatment verification. Methods: for our study we used the FLUKA Monte Carlo code and artificially generated CT scans to simulate in-beam P
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Lang, Karol. "Image-Guided FLASH ProtonTherapy. A dream? Naivety?Arrogance? Or a Necessity?" Bio-Algorithms and Med-Systems 20, Special Issue (2024): 17–26. https://doi.org/10.5604/01.3001.0054.8930.

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<b>Objective:</b> The in-vivo therapy guidance by imaging and dosimetry of proton irradiations, generically known as proton range verification, are some of the most underinvested aspects of radiation oncology. They trail behind other advances in radiation therapy due to the scarcity of sensitive instruments compounded by the lack of treatment protocols for precision monitoring of effects of beam radiation. This is despite that such measurements may dramatically enhance the treatment accuracy and lower the postradiation toxicity, thus improving the entire outcome of cancer therapy.
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Brombal, L., D. Barbosa, N. Belcari, et al. "Proton therapy treatment monitoring with in-beam PET: Investigating space and time activity distributions." Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment 861 (July 2017): 71–76. http://dx.doi.org/10.1016/j.nima.2017.05.002.

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4

Kraan, A. C., G. Battistoni, N. Belcari, et al. "First tests for an online treatment monitoring system with in-beam PET for proton therapy." Journal of Instrumentation 10, no. 01 (2015): C01010. http://dx.doi.org/10.1088/1748-0221/10/01/c01010.

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Cesar, John P., Firas Abouzahr, Paulo Crespo, et al. "First PET Studies of a FLASH Proton Beam: Summary and Future Prospects." Bio-Algorithms and Med-Systems 20, Special Issue (2024): 49–54. https://doi.org/10.5604/01.3001.0054.9140.

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<b>Objectives:</b> Proton therapy, while highly effective and successful, still lacks a key feature: the ability to assess, in-vivo, the dose and end-point location of irradiations. Known as proton range verification, this capability can be realized by incorporating positron emission tomography (PET) systems in both conventional and emerging modalities, such as FLASH proton therapy. FLASH itself may revolutionize radiation oncology with its purported ability to better spare healthy tissues, but only if the underlying mechanisms can be understood. We summarize our work towards estab
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Müller, Cristina, Maria De Prado Leal, Marco D. Dominietto, et al. "Combination of Proton Therapy and Radionuclide Therapy in Mice: Preclinical Pilot Study at the Paul Scherrer Institute." Pharmaceutics 11, no. 9 (2019): 450. http://dx.doi.org/10.3390/pharmaceutics11090450.

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Proton therapy (PT) is a treatment with high dose conformality that delivers a highly-focused radiation dose to solid tumors. Targeted radionuclide therapy (TRT), on the other hand, is a systemic radiation therapy, which makes use of intravenously-applied radioconjugates. In this project, it was aimed to perform an initial dose-searching study for the combination of these treatment modalities in a preclinical setting. Therapy studies were performed with xenograft mouse models of folate receptor (FR)-positive KB and prostate-specific membrane antigen (PSMA)-positive PC-3 PIP tumors, respectivel
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7

McDonough, James, and Brent Tinnel. "The University of Pennsylvania/Walter Reed Army Medical Center Proton Therapy Program." Technology in Cancer Research & Treatment 6, no. 4_suppl (2007): 73–76. http://dx.doi.org/10.1177/15330346070060s412.

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The design of the proton therapy center being constructed at the University of Pennsylvania is based on several principles that distinguish it from other proton facilities. Among these principles is the recognition that advances in imaging, and particularly in functional imaging, will have a large impact on radiotherapy in the near future and that the conformation of proton dose distributions can utilize that information to a larger degree than other treatment techniques. The facility will contain four-dimensional CT-simulators, an MR-simulator capable of spectroscopy, and a PET-CT scanner. A
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8

Rosso, V., G. Battistoni, N. Belcari, et al. "In-treatment tests for the monitoring of proton and carbon-ion therapy with a large area PET system at CNAO." Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment 824 (July 2016): 228–32. http://dx.doi.org/10.1016/j.nima.2015.11.017.

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Ahmed Hasan Al-Jalawee. "Review: cutting-edge developments in radiotherapy: Advances in imaging, motion management and AI-driven treatment optimization." World Journal of Biology Pharmacy and Health Sciences 21, no. 3 (2025): 012–17. https://doi.org/10.30574/wjbphs.2025.21.3.0176.

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Radiotherapy has long been a cornerstone in cancer treatment, utilizing ionizing radiation to target and destroy malignant cells. Recent technological and biological advancements have significantly enhanced treatment precision, reduced radiation exposure to healthy tissues, and improved patient outcomes. This review explores key innovations in radiotherapy, focusing on imaging advancements, motion management techniques, and artificial intelligence (AI)-driven treatment optimization. MRI-guided radiotherapy (MRgRT) has revolutionized tumor visualization, allowing real-time adaptation to anatomi
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10

Kraan, Aafke Christine, Martina Moglioni, Giuseppe Battistoni, et al. "Using the gamma-index analysis for inter-fractional comparison of in-beam PET images for head-and-neck treatment monitoring in proton therapy: A Monte Carlo simulation study." Physica Medica 120 (April 2024): 103329. http://dx.doi.org/10.1016/j.ejmp.2024.103329.

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Dissertations / Theses on the topic "Proton therapy, PET, FLUKA, treatment monitoring"

1

Topi, Albana. "Positron Emission Tomography Applied in Proton Therapy for Treatment Delivery Verification." Doctoral thesis, Università di Siena, 2018. http://hdl.handle.net/11365/1066400.

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The aim of this thesis is to investigate the use of a dedicated system for proton therapy treatments monitoring based on the PET technique. It focuses on the use of data acquired shortly after irradiations, which is currently not yet fully explored. An ad hoc detector called DoPET was built and used for several experiments. This stationary dual-head detector, along with an on-purpose optimised reconstruction software, is capable of reconstructing the β+ activated volume, acquiring data also during treatment for cyclotron based facilities. Currently, this system is one of the few PET systems wo
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Journal articles
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