To see the other types of publications on this topic, follow the link: Protozoan parasites.
Journal articles on the topic 'Protozoan parasites'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the top 50 journal articles for your research on the topic 'Protozoan parasites.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.
1
Abbas, Hussam Abdullah. "Epidemiological study of human diarrhea- causing protozoa in Wasit governorate." E3S Web of Conferences 391 (2023): 01127. http://dx.doi.org/10.1051/e3sconf/202339101127.
Full textAbstract:
The study and Laboratory examinations were performed between (January 2021 and April 2021). We conducted an epidemiological study of intestinal protozoa parasites in the Wasit governorate. The number of samples that collected 500 stool samples in the city center of Kut and Numaniah city. Samples were collected by container from both sexes male and female have the symptom of the infected protozoan parasite, and examined by microscopy with a wet smear method, use a light microscope to detect these protozoan parasites morphologically . We recorded the highest percentage of protozoan parasite infection Entamoeba histolytica (84%) and the lowest percentage of parasite infection Giardia lamblia (16%). The result of laboratory tests showed that males were infected with a higher rate (54%) and the lowest percentage of females (46%). Due to the importance of the intestinal protozoa parasites in the community, this study was encouraging due to the high infection rate.
2
SCHAUMBURG, F., D. HIPPE, P. VUTOVA, and C. G. K. LÜDER. "Pro- and anti-apoptotic activities of protozoan parasites." Parasitology 132, S1 (March 2006): S69—S85. http://dx.doi.org/10.1017/s0031182006000874.
Full textAbstract:
During infection, programmed cell death, i.e. apoptosis, is an important effector mechanism of innate and adaptive host responses to parasites. In addition, it fulfils essential functions in regulating host immunity and tissue homeostasis. Not surprisingly, however, adaptation of parasitic protozoa to their hosts also involves modulation or even exploitation of cell death in order to facilitate parasite survival in a hostile environment. During recent years, considerable progress has been made in our understanding of apoptosis during parasitic infections and there is now convincing evidence that apoptosis and its modulation by protozoan parasites has a major impact on the parasite-host interaction and on the pathogenesis of disease. This review updates our current knowledge on the diverse functions apoptosis may fulfil during infections with diverse protozoan parasites including apicomplexans, kinetoplastids and amoebae. Furthermore, we also summarize common mechanistic themes of the pro- and anti-apoptotic activities of protozoan parasites. The diverse and complex effects which parasitic protozoa exert on apoptotic cell death within the host highlight fascinating interactions of parasites and their hosts. Importantly, they also stress the importance of further investigations before the modulation of host cell apoptosis can be exploited to combat parasitic infections.
3
Ndiaye, Mouhamadou, Khadim Diongue, Mame Cheikh Seck, Mamadou Alpha Diallo, Ekoué Kouevidjin, Aida Sadikh Badiane, and Daouda Ndiaye. "Retrospective Assessment of The Intestinal Protozoan Distribution in Patients Admitted to The Hospital Aristide Le Dantec in Dakar, Senegal, from 2011 to 2020." Parasitologia 3, no. 1 (December 23, 2022): 1–12. http://dx.doi.org/10.3390/parasitologia3010001.
Full textAbstract:
Infectious parasites, especially the intestinal protozoan parasites, continue to be a major public health problem in Africa, where many of the same factors contribute to the transmission of these parasites. This study was conducted to investigate the parasites causing intestinal protozoal infections diagnosed in Aristide Le Dantec hospital (Senegal). Direct examination and the Ritchie technique were used. Among the 3407 stool samples studied, 645 demonstrated the presence of intestinal protozoa in single parasitism, biparasitism, or polyparasitism, representing a prevalence of 18.93%. Out of a total of 645 protozoa, 579 (16.99%) were identified in monoparasitism in the following order: Entamoeba coli (6.87%) and Blastocystis hominis (5.69%) for low pathogenic species, and Entamoeba histolytica/dispar (2.31%) and Giardia intestinalis (1.32%) for pathogenic species. The rates of biparasitism and polyparasitism were 1.88% and 0.06%, respectively. The highest rate of parasites was 24.83% between the ages of 0–15 years. A logistical regression model indicated that intestinal protozoan infections were not associated with age groups. There was an association between age groups and Giardia intestinalis and Blastocystis hominis (p < 0.05). These results demonstrated the frequency of intestinal protozoa in Senegal. There is a need to implement treatment, prevention, and control measures to limit the circulation of these protozoan infections.
4
EIRAS, JORGE C., RICARDO M. TAKEMOTO, GILBERTO C. PAVANELLI, and JOSÉ L. LUQUE. "Checklist of Protozoan parasites of fishes from Brazil." Zootaxa 3221, no. 1 (March 5, 2012): 1. http://dx.doi.org/10.11646/zootaxa.3221.1.1.
Full textAbstract:
Provided is a list of the protozoan parasites of freshwater and marine fishes from Brazil. This report includes informationabout the site of infection, host habitat, localities and references of 100 parasite species (1 amoeba, 70 flagellates, 13 api-complexa and 16 ciliates) distributed among 112 different host species, mainly from freshwater. It is concluded that thediversity of protozoan parasites from Brazilian fish is understudied, and it is suggested that appropriate measures be taken in the research efforts to increase studies on the diversity of Protozoans parasites of fish from Brazil.
5
Omeji, S., S. G. Solomon, and E. S. Idoga. "A Comparative Study of the Common Protozoan Parasites ofClarias gariepinusfrom the Wild and Cultured Environments in Benue State, Nigeria." Journal of Parasitology Research 2011 (2011): 1–8. http://dx.doi.org/10.1155/2011/916489.
Full textAbstract:
A total of one hundred and twentyClarias gariepinuscomprising 30 dead and 30 live fishes were examined for protozoan parasites infestation, sixty each from the wild and a pond (cultured environment) over a period of six months.Ichthyophthirius multifiliiswas the most common protozoan parasites found inC. gariepinusfrom the wild (River Benue) and cultured (pond) environments. These protozoan parasites constitute 37.08% of the total parasites encountered for fishes in the pond and 42.51% of fishes in the wild. Among the body parts of the sampled fishes from the pond, the gills had the highest parasite load (38.86%). Also, the gills had the highest parasite load (40.54%) among the body parts of the fishes sampled from the wild. Fishes not infested with any protozoan parasites from the pond constituted 36.70% of the total fish sampled. On the other hand, fishes not infested with any protozoan parasites from the wild constituted 31.65% of the total fish sampled. Female fishes had more protozoan parasites than the male fishes. Bigger fishes of total length (25–48 cm) had more parasite load than the smaller ones (19–24 cm). Also, fishes between 150–750 g had more parasite load than the smaller ones of less than 150 g. Protozoan parasite load of fish from the cultured environment (pond) did not differ significantly (P<0.05) from those from River Benue (wild).
6
Visvesvara, Govinda S., and Lynne S. Garcia. "Culture of Protozoan Parasites." Clinical Microbiology Reviews 15, no. 3 (July 2002): 327–28. http://dx.doi.org/10.1128/cmr.15.3.327-328.2002.
Full textAbstract:
SUMMARY The in vitro culture of protozoan parasites involves highly complex procedures, which are subject to many variables. These parasites have very complex life cycles and, depending on the life cycle stage, may require different culture parameters. However, in vitro cultivation is important for many reasons, some of which include: diagnosis, antigen and antibody production, assessment of parasite immune modulating capabilities, drug screening, improvements in chemotherapy, differentiation of clinical isolates, determination of strain differences, vaccine production, development of attenuated strains, and the continued supply of viable organisms for studying host-parasite interactions.
7
Custodio, H. "Protozoan Parasites." Pediatrics in Review 37, no. 2 (February 1, 2016): 59–71. http://dx.doi.org/10.1542/pir.2015-0006.
Full text
8
Martins, Mauricio Laterça, Lucas Cardoso, Natalia Marchiori, and Santiago Benites de Pádua. "Protozoan infections in farmed fish from Brazil: diagnosis and pathogenesis." Revista Brasileira de Parasitologia Veterinária 24, no. 1 (March 2015): 1–20. http://dx.doi.org/10.1590/s1984-29612015013.
Full textAbstract:
The Phylum Protozoa brings together several organisms evolutionarily different that may act as ecto or endoparasites of fishes over the world being responsible for diseases, which, in turn, may lead to economical and social impacts in different countries. Apart from the recent advances for the diagnosis of fish diseases in Brazil, little is known on the protozoan parasites and their relationship with environment and host. This revision presents the most important protozoan parasites found in farmed fish from Brazil, not only with emphasis on its diagnosis, biology, transmission and host-parasite relationship, but also on some information that may be useful to researchers in determining the correct diagnosis in fish farms.
9
Silva, Liliana M. R., Tamara Muñoz-Caro, Rafael A. Burgos, Maria A. Hidalgo, Anja Taubert, and Carlos Hermosilla. "Far beyond Phagocytosis: Phagocyte-Derived Extracellular Traps Act Efficiently against Protozoan ParasitesIn VitroandIn Vivo." Mediators of Inflammation 2016 (2016): 1–13. http://dx.doi.org/10.1155/2016/5898074.
Full textAbstract:
Professional mononuclear phagocytes such as polymorphonuclear neutrophils (PMN), monocytes, and macrophages are considered as the first line of defence against invasive pathogens. The formation of extracellular traps (ETs) by activated mononuclear phagocytes is meanwhile well accepted as an effector mechanism of the early host innate immune response acting against microbial infections. Recent investigations showed evidence that ETosis is a widely spread effector mechanism in vertebrates and invertebrates being utilized to entrap and kill bacteria, fungi, viruses, and protozoan parasites. ETs are released in response to intact protozoan parasites or to parasite-specific antigens in a controlled cell death process. Released ETs consist of nuclear DNA as backbone adorned with histones, antimicrobial peptides, and phagocyte-specific granular enzymes thereby producing a sticky extracellular matrix capable of entrapping and killing pathogens. This review summarizes recent data on protozoa-induced ETosis. Special attention will be given to molecular mechanisms of protozoa-induced ETosis and on its consequences for the parasites successful reproduction and life cycle accomplishment.
10
Karim, Mt Tahmina, Hamida Khanum, and Sharmin Musa. "Occurrence of enteric parasites and their risk factors among the female inhabitants of lower socioeconomic groups in Dhaka city." Asian Journal of Medical and Biological Research 4, no. 4 (December 30, 2018): 343–50. http://dx.doi.org/10.3329/ajmbr.v4i4.40106.
Full textAbstract:
The present study was conducted to investigate the intestinal parasites. A total of 900 female inhabitants of lower socioeconomic groups in Dhaka city were examined during Sep 2013 to Aug 2015, prevalence of gastrointestinal parasitic infestation was 66.22% and 26 parasite species were identified, of which ten species were protozoans, six cestodes, four trematodes and six nematodes. Prevalence of nematoda was the highest (57.55%), then cestode (38.67%), protozoa (19.22%) and lowest was found in trematode (4.11%). Entamoeba histolytica (10.44%) indicates severe faecal contamination among protozoan parasites, while in cestodes Hymenolepis nana (22.78%), in trematodes Fasciolopsis buski (2.11%) and in nematodes Ascaris lumbricoides (38%) were highly prevalent. In twelve study areas, the highest prevalence was found in Kamrangichar (87.5%) and children of age group 1-15 years (75.65%) were mostly affected by intestinal parasite.
Asian J. Med. Biol. Res. December 2018, 4(4): 343-350
11
Kabita, Fatima Nahar, Md Aminul Islam Bhuiyan, and Zannatun Nahar Jhinu. "A Checklist on the Protozoan Parasites of Freshwater Fishes of Bangladesh." Bangladesh Journal of Zoology 48, no. 1 (June 29, 2020): 21–35. http://dx.doi.org/10.3329/bjz.v48i1.47873.
Full textAbstract:
The current work has been proposed to accumulate baseline information regarding prevalence, diversity and distribution of the protozoan parasites found in the freshwater fishes of Bangladesh from its inception to 2019. This is an attempt to compile a baseline data on protozoan parasites of freshwater fishes in Bangladesh. A total of thirty four articles were reviewed whereas sixteen articles reported systematic, taxonomic and morphometric analysis of protozoan parasites, five articles described seasonal parasitic infestation in carp fishes including protozoan parasites, seven articles reported overall parasitic infestation along with protozoan infection, three articles described protozoan infection in consort with the histo-pathological analysis, one article revealed the occurrence of one protozoan parasite named Trypanosoma sp. and one study described monthly fluctuation of overall parasitic infection together with protozoan infestation. A number of thirty four freshwater fish species under nine orders in Bangladesh were retrieved on the mentioned articles and found 48 species of protozoan parasites under 19 genera. Noticeably, parasites under genus Trichodina was frequently found in the freshwater fish species. Most of the parasites were found from the gills (micro-habited) of the host fish. To sum up, from this compilation a primary database of protozoan parasites of freshwater fish species might be expected to establish that will be supportive for further extensive study.
Bangladesh J. Zool. 48(1): 21-35, 2020
12
Suwanti, Lucia Tri. "IDENTIFICATION AND PREVALENCE OF GASTROINTESTINAL PARASITES IN BEEF CATTLE IN SIAK SRI INDRAPURA, RIAU, INDONESIA." Indonesian Journal of Tropical and Infectious Disease 7, no. 6 (October 9, 2019): 155. http://dx.doi.org/10.20473/ijtid.v7i6.10392.
Full textAbstract:
Gastrointestinal (GI) parasites infection are one of the major constraints cattle farm in tropical countries including Indonesia and some of GI parasites in cattle have the potential to transmit to humans. This study was aimed to identify and determine the level of prevalence of gastrointestinal (GI) parasites in beef cattle in Siak Sri Indrapura District, Riau Province, Indonesia. This research was conducted on 100 beef cattle consisted of, respectively, 32, 34 and 34 cattles from Bungaraya, Sabak Auh, and Dayun sub-district. The characteristic of sample such as age and sex cattle, cage management, feed and drinking water were recorded. Native, sedimentation and sucrose flotation methods were used to find protozoa and eggs worm. We assessed GI parasites based on finding eggs worm, protozoan cyst and coccidial oocysts in stool samples and identification of GI parasite was based on the morphology and size of the eggs worm and cysts or oocysts of protozoan. The result showed that all of 100 feces samples that examined 100% positive infection for parasites. There were eleven types of gastrointestinal parasites that have been identified, 6 genera of protozoan and 5 genera of worms. The prevalence of gastrointestinal parasites in beef cattles in Siak Sri Indrapura District were Blastocystis sp. (100%), Entamoeba sp. (90%), Eimeria sp. (53%), Giardia sp. (7%), Balantidium coli (4%), Cryptosporidium sp. (2%) Oesophagustomum sp. (45%), Toxocara vitulorum (20%), Moniezia expansa (9%), Trichuris sp. (5%), and Fasciola sp. (4%). In conclusion, Siak Sri Indrapura Riau is an endemic GI parasite and this can threaten the health of livestock and potentially as a zoonotic transmission.
13
Deng, Silu, Marion L. Graham, and Xian-Ming Chen. "The Complexity of Interferon Signaling in Host Defense against Protozoan Parasite Infection." Pathogens 12, no. 2 (February 15, 2023): 319. http://dx.doi.org/10.3390/pathogens12020319.
Full textAbstract:
Protozoan parasites, such as Plasmodium, Leishmania, Toxoplasma, Cryptosporidium, and Trypanosoma, are causative agents of health-threatening diseases in both humans and animals, leading to significant health risks and socioeconomic losses globally. The development of effective therapeutic and prevention strategies for protozoan-caused diseases requires a full understanding of the pathogenesis and protective events occurring in infected hosts. Interferons (IFNs) are a family of cytokines with diverse biological effects in host antimicrobial defense and disease pathogenesis, including protozoan parasite infection. Type II IFN (IFN-γ) has been widely recognized as the essential defense cytokine in intracellular protozoan parasite infection, whereas recent studies also revealed the production and distinct function of type I and III IFNs in host defense against these parasites. Decoding the complex network of the IFN family in host–parasite interaction is critical for exploring potential new therapeutic strategies against intracellular protozoan parasite infection. Here, we review the complex effects of IFNs on the host defense against intracellular protozoan parasites and the crosstalk between distinct types of IFN signaling during infections.
14
Gupta, M., M. Sinha, and N. Raizada. "Opportunistic Intestinal Protozoan Parasitic Infection in HIV Positive Patient in Jamnagar, Gujarat." SAARC Journal of Tuberculosis, Lung Diseases and HIV/AIDS 5, no. 1 (May 7, 2010): 21–24. http://dx.doi.org/10.3126/saarctb.v5i1.3079.
Full textAbstract:
The case definition of AIDS encompasses a spectrum of infections and malignancies, labelled as opportunistic infections. In recent years, numerous studies have outlined the emergence of opportunistic gastrointestinal protozoa that have caused diarrhoeal illness among HIV - AIDS patients. Purpose of present study was to determine the prevalence of opportunistic intestinal protozoal parasites in HIV positive patients with or without diarrhoea. A total of 100 stool samples of HIV positive patients were examined for protozoal parasites by microscopy. Protozoal parasites were detected in 25 HIV positive patients; in 41.37 % of patients with diarrhoea and in 2.38% of patients without diarrhoea. Isospora belli appeared to be a predominant parasite associated with diarrhoea among HIV patients. Cryptosporidium revealed of its asymptomatic carriage along with its association with acute and chronic diarrhoea. Prevalence of Microsporidia and Cyclospora cayetenensis was found to be very low. Key words: HIV; diarrhoea; opportunistic protozoa. DOI: 10.3126/saarctb.v5i1.3079 SAARC J. Tuber. Lung Dis. HIV/AIDS 2008 Vol.5(1) 21-24
15
Belov, YU A., T. V. Tabakaeva, D. V. Pankratov, E. M. Shchelkanov, A. L. Surovyi, I. A. Popov, A. V. Tabakaev, L. V. Zheleznova, I. V. Galkina, and M. YU Shchelkanov. "Endoparasites of wild boars (Sus scrofa) in Primorsky Krai, Russia." Helminthologia 59, no. 2 (June 1, 2022): 165–69. http://dx.doi.org/10.2478/helm-2022-0018.
Full textAbstract:
Summary This study identified helminthic species among wild boars (Sus scrofa) in Primorsky Krai, Russia. In total, 66 fecal samples were taken from wild boars and examined using the floatation-sedimentation method to identify helminths eggs and protozoan cysts. Age and sex were estimated for each host animal investigated. The helminthic fauna of the wild boars examined involved six parasite genera, but 4 are helminths and 2 are protozoans: the nematodes Metastrongylus spp., Trichuris suis, Capillaria sp. and Ascaris suum; and the protozoan parasites Eimeria sp. and Cystoisospora suis. The most prevalent parasite was Metastrongylus spp. (13.6 %) followed by Trichuris suis (7.6 %). The other parasites found were Eimeria sp. (3 %), Ascaris suum (3 %), Capillaria sp. (1.5 %) and Cystoisospora suis (1.5 %). Not found positive correlation between the host’s age and sex and the parasite prevalence. This was the first detailed study on helminths infections among wild boars in Primorsky Krai.
16
Marshall, M. M., D. Naumovitz, Y. Ortega, and C. R. Sterling. "Waterborne protozoan pathogens." Clinical Microbiology Reviews 10, no. 1 (January 1997): 67–85. http://dx.doi.org/10.1128/cmr.10.1.67.
Full textAbstract:
Protozoan parasites were the most frequently identified etiologic agents in waterborne disease outbreak from 1991 to 1994. The waterborne parasites Giardia lamblia, Naegleria fowleri, Acanthamoeba spp., Entamoeba histolytica, Cryptosporidium parvum, Cyclospora cayetanesis, Isospora belli, and the microsporidia are reviewed. For each parasite, the review includes history, life cycle, incidence, symptoms, and therapy. Clinical detection methods are compared, and emerging technologies are discussed. Information on the association of these parasites with waterborne outbreaks is reviewed. Current information on protozoan parasites identified as etiological agents in waterborne outbreaks is discussed. Water industry issues related to recent disease outbreaks are examined in the context of water quality testing regulations for G. lamblia and those proposed for C. parvum. The review identifies the limitations of the American Society of Testing and Materials water-testing method for these parasites. An overview of federal regulations affecting the water industry and laboratories that test for water quality is also provided. The article highlights the importance of the clinical laboratory as a frontline defense for the detection of infectious organisms. The review points to the need for clinical laboratories, physicians, and public health personnel to cooperatively plan and assess the challenge of meeting this potential public health threat.
17
Blazhekovikj - Dimovska, Dijana. "PROTOZOAN PARASITES IN COMMON CARP (CYPRINUS CARPIO, L. 1758) FROM CYPRINID AQUACULTURE FACILITY IN PELAGONIA REGION (BITOLA, MACEDONIA)." Knowledge International Journal 31, no. 3 (June 5, 2019): 675–80. http://dx.doi.org/10.35120/kij3103675b.
Full textAbstract:
The aim of this study was to determine the protozoan parasites in common carp (Cyprinus carpio, L. 1758) from the largest cyprinid aquaculture facility in Macedonia, located in Pelagonia region (Bitola). This study was carried out by seasons, in a period of three years. A total of 212 specimens of common carp were examined and 134 fish (63.20%) were infected with protozoan parasites. Representatives of Protozoa were most commonly occurred during the spring (in 58.27 % of the fish examined), than in winter (55.21 %), summer (39.07 %) and the lowest in autumn (35.64 %).In common carp from this cyprinid fish farm the presence of 4 protozoa species was established: Myxobolus müelleri, Myxobolus encephalicus, Thelohanellus nikolskii and Trichodina sp. The mean intensity with protozoan parasites in common carp was 3.60, while the prevalence 10.20 %.
18
Tarannum, Asfiha, Cristian Camilo Rodríguez-Almonacid, Jorge Salazar-Bravo, and Zemfira N. Karamysheva. "Molecular Mechanisms of Persistence in Protozoan Parasites." Microorganisms 11, no. 9 (September 7, 2023): 2248. http://dx.doi.org/10.3390/microorganisms11092248.
Full textAbstract:
Protozoan parasites are known for their remarkable capacity to persist within the bodies of vertebrate hosts, which frequently results in prolonged infections and the recurrence of diseases. Understanding the molecular mechanisms that underlie the event of persistence is of paramount significance to develop innovative therapeutic approaches, given that these pathways still need to be thoroughly elucidated. The present article provides a comprehensive overview of the latest developments in the investigation of protozoan persistence in vertebrate hosts. The focus is primarily on the function of persisters, their formation within the host, and the specific molecular interactions between host and parasite while they persist. Additionally, we examine the metabolomic, transcriptional, and translational changes that protozoan parasites undergo during persistence within vertebrate hosts, focusing on major parasites such as Plasmodium spp., Trypanosoma spp., Leishmania spp., and Toxoplasma spp. Key findings of our study suggest that protozoan parasites deploy several molecular and physiological strategies to evade the host immune surveillance and sustain their persistence. Furthermore, some parasites undergo stage differentiation, enabling them to acclimate to varying host environments and immune challenges. More often, stressors such as drug exposure were demonstrated to impact the formation of protozoan persisters significantly. Understanding the molecular mechanisms regulating the persistence of protozoan parasites in vertebrate hosts can reinvigorate our current insights into host–parasite interactions and facilitate the development of more efficacious disease therapeutics.
19
Chinedu, Azudialu Bede, Nkem Benjamin Iheanyichukwu, Calistus Muodebe Nwokeji, and Nnadozie R. I. Austine. "Intestinal Protozoans among HIV Patients in a Rural Setting, Southern Nigeria." Journal of Disease and Global Health 16, no. 3 (December 29, 2023): 6–12. http://dx.doi.org/10.56557/jodagh/2023/v16i38504.
Full textAbstract:
Opportunistic parasitic protozoan infections in HIV infected patients remain a worldwide public health concern. A cross sectional study on HIV patients was carried out in some parts of Imo State with a view of assessing the prevalence of intestinal protozoan parasites. Stool samples were collected and analysed applying standard techniques. Overall, four species of protozoan parasites were isolated namely, C.parvum, E.histolytica, G.lamblia and Ent. coli. Total prevalence is highest (52.2%) amongst the age group of ≤27 years, followed by 45-48years(27.8%) while the least prevalence(11.8%) is recorded for the age group of 49 years and above. More female (26.3%) were infected than male (25.4%). Significant association between age and protozoan prevalencewas noted(p-value=0.007; X2=32.998a, df=16). Further analysis selecting Cramer’s V which is the measure of association based on chi-square shows a weak dependence between age and parasite prevalence (Cramer’s V-value = 0.286). Pearson correlation shows a positive, weak (R=0.170; sig.=0.089c) relationship between age and protozoan parasite prevalence. Test of association between gender and intestinal protozoan parasites shows a non-significant association(p=0.280;X2=5.069a), weak dependence(Cramer’s V-value = 0.280) and a negative, weak relationship between gender and parasite prevalence(R=-0.042; sig=0.674c). Subjects with CD4count <200µ/ml recorded the highest(40.0%) prevalence of intestinal protozoan parasite while 200-349µ/ml recorded the least prevalence(4.0%).Significant association exists between CD4 count and parasite prevalence(x2=53.9a, df=12,p=0.001);then Cramer’s v test shows a medium-strong dependence. High prevalence (37.0%) of intestinal protozoan parasites is recorded for subjects not on HAART while low prevalence (12.8%) is recorded for those on HAART; with Significant association (x2=16.157a, df=4, p=0.003) and medium-strong dependence (Cramer’s v =0.40).The result of this study shows that intestinal parasites are of public health concern among immunocompromised individuals and calls for urgent attention of relevant stakeholders
20
Barzegar, Maryam, Mehdi Raissy, and Shokoofeh Shamsi. "Protozoan Parasites of Iranian Freshwater Fishes: Review, Composition, Classification, and Modeling Distribution." Pathogens 12, no. 5 (April 27, 2023): 651. http://dx.doi.org/10.3390/pathogens12050651.
Full textAbstract:
This article investigates the occurrence and distribution of parasitic protozoa of Iranian freshwater fishes (both farmed and wild). Our search shows 26 known parasitic protozoan species were recorded from 52 freshwater fish species across different ecoregions of Iran. Most of these fish are edible. While none of the identified protozoan parasites are of zoonotic importance, our study does not exclude presence of zoonotic species in Iranian fishes. Present data suggest the northern and western regions of the country are the main macrohabitat of protozoa (35 parasitic records reported), with the greatest concentration of parasitic protozoa occurring in the Urmia basin in Iran’s northwest. The clustered distribution pattern of protozoa among freshwater fish was also more evident in the northern and western parts of the country. The gills and skin were the most infected microhabitats for parasitic protozoa. The highest number of parasites was observed in the fish family Cyprinidae with nine species found in the native fish, Capoeta capoeta. The most diverse host range was observed in the holotrich ciliate, Ichthyophthirius multifiliis isolated from 46 cyprinid species in 39 different locations. However, due to the great richness of fish and extreme habitat diversity, parts of the parasite fauna of Iranian freshwater fish are still poorly understood. Furthermore, current and future changes in climate and environmental parameters, and anthropogenic interventions are likely to affect fish hosts and their parasites.
21
Dawson, David. "Foodborne protozoan parasites." International Journal of Food Microbiology 103, no. 2 (August 2005): 207–27. http://dx.doi.org/10.1016/j.ijfoodmicro.2004.12.032.
Full text
22
Shoda, Lisl K. M., Kimberly A. Kegerreis, Carlos E. Suarez, Isabel Roditi, Ricardo S. Corral, Gustavo M. Bertot, Junzo Norimine, and Wendy C. Brown. "DNA from Protozoan Parasites Babesia bovis, Trypanosoma cruzi, and T. brucei Is Mitogenic for B Lymphocytes and Stimulates Macrophage Expression of Interleukin-12, Tumor Necrosis Factor Alpha, and Nitric Oxide." Infection and Immunity 69, no. 4 (April 1, 2001): 2162–71. http://dx.doi.org/10.1128/iai.69.4.2162-2171.2001.
Full textAbstract:
ABSTRACT The activation of innate immune responses by genomic DNA from bacteria and several nonvertebrate organisms represents a novel mechanism of pathogen recognition. We recently demonstrated the CpG-dependent mitogenic activity of DNA from the protozoan parasiteBabesia bovis for bovine B lymphocytes (W. C. Brown, D. M. Estes, S. E. Chantler, K. A. Kegerreis, and C. E. Suarez, Infect. Immun. 66:5423–5432, 1998). However, activation of macrophages by DNA from protozoan parasites has not been demonstrated. The present study was therefore conducted to determine whether DNA from the protozan parasites B. bovis, Trypanosoma cruzi, and T. brucei activates macrophages to secrete inflammatory mediators associated with protective immunity. DNA fromEscherichia coli and all three parasites stimulated B-lymphocyte proliferation and increased macrophage production of interleukin-12 (IL-12), tumor necrosis factor alpha (TNF-α), and nitric oxide (NO). Regulation of IL-12 and NO production occurred at the level of transcription. The amounts of IL-12, TNF-α, and NO induced by E. coli and protozoal DNA were strongly correlated (r 2 > 0.9) with the frequency of CG dinucleotides in the genome, and immunostimulation by DNA occurred in the order E. coli ≥ T. cruzi > T. brucei > B. bovis. Induction of inflammatory mediators by E. coli, T. brucei, and B. bovis DNA was dependent on the presence of unmethylated CpG dinucleotides. However, at high concentrations,E. coli and T. cruzi DNA-mediated macrophage activation was not inhibited following methylation. The recognition of protozoal DNA by B lymphocytes and macrophages may provide an important innate defense mechanism to control parasite replication and promote persistent infection.
23
Jha, Bina, Ranjana Gupta, Janak Raj Subedi, and Bijay Chhetri. "Gastrointestinal parasites of feral pigeon (Columba livia Gmelin, 1789) at two temples of Kathmandu valley." Journal of Animal Science and Veterinary Medicine 8, no. 2 (April 30, 2023): 23–28. http://dx.doi.org/10.31248/jasvm2022.330.
Full textAbstract:
Protozoans, helminths and other gastrointestinal (GI) parasitic infections in Aves are an imperative but often ignored topic in rising nations like Nepal. Accurate inspections of GI parasites in feral pigeons inform pragmatic treatment regimens. In a prospective examination of intestinal parasites in the coprological study of feral pigeons in April 2016, a total of 120 samples were preserved in 2.5% potassium dichromate and examined by microscopy of direct and concentrated faecal sample techniques to detect ova, larvae, and oocysts of parasites. Altogether 109 (90.83%) samples were positive with 6 genera of GI parasites. The study identified one genus of protozoa: Eimeria sp. (43.34%) and five genera of helminths: Capillaria sp. (51.67%), Ascaridia sp. (27.50%), Heterakis sp. (19.17%), Syngamus sp. (4.17%) and Tetrameres sp. (1.70%). The prevalence rate of helminth parasites (83.34%) was higher than the prevalence rate of protozoan parasites (43.34%). The present study revealed a significant difference in the prevalence of helminths and protozoan parasites (χ²=15.14, p<0.05). However, the prevalence of gastrointestinal parasites showed no significant variation with respect to single and mixed infection (χ² =1.56, p>0.05). The present study examined a higher prevalence rate of gastrointestinal parasites due to a lack of deworming programs in feral pigeons and a lack of sustainable action designs. Therefore, the sustainable action design and its implementation to control parasitic infection and reduce the health hazards of feral temple pigeons were recommended.
24
Mhaisen, F. T., A. H. Ali, and N. R. Khamees. "Checklists of Protozoans and Myxozoans of Freshwater and Marine Fishes of Basrah Province, Iraq." Mesopotamian Journal of Marine Sciences 31, no. 1 (April 14, 2022): 29–52. http://dx.doi.org/10.58629/mjms.v31i1.108.
Full textAbstract:
Reviewing the literature on all the protozoans and myxozoans parasitizing freshwater and marine fishes of Basrah Province, Iraq indicated the presence of 25 protozoans (one sarcodinid, six mastigophorans, one opalinid, four epicomplexans and 13 ciliophorans) as well as ten myxozoans. Some of these parasites infect skin, fins and gills of their hosts while others are internal parasites of fish muscles, body cavity and different body viscera. Apart from one taxon which was recorded from a marine locality, the remaining taxa were recorded from freshwater localities. The total number of protozoan and myxozoan species recorded for each fish host species fluctuated from a minimum of one parasite species in 11 fish hosts to a maximum of 15 parasite species in Silurus triostegus. Number of fish hosts reported for these parasites fluctuated from one host in case of 21 parasite species to a maximum of 19 host species in case of the ciliophoran Trichodina domerguei.
25
Saunders, Eleanor, David De Souza, James McRae, Vladimir Likic, and Malcolm McConville. "Metabolomic analysis of protozoan parasites." Microbiology Australia 32, no. 4 (2011): 144. http://dx.doi.org/10.1071/ma11144.
Full textAbstract:
Protozoan parasites cause a number of important diseases in humans, including malaria, African trypanosomiasis, Chagas disease and the leishmaniases. Current therapeutics for these diseases are limited and their effectiveness is being further undermined by the emergence of drug-resistant parasite strains. Parasite genome sequencing projects have provided new insights into the metabolic capacity of these pathogens and have highlighted potential drug targets. However, these genome-based reconstructions of metabolic networks are incomplete and we still have only a limited understanding of the metabolic requirements of these pathogens during infection. Metabolomics has emerged as a powerful new tool for investigating parasite metabolism and host responses, complementing more established omics technologies as well as being useful as a stand-alone technique.
26
Amezcua Vesely, María C., Daniela A. Bermejo, Carolina L. Montes, Eva V. Acosta-Rodríguez, and Adriana Gruppi. "B-Cell Response during Protozoan Parasite Infections." Journal of Parasitology Research 2012 (2012): 1–8. http://dx.doi.org/10.1155/2012/362131.
Full textAbstract:
In this review, we discuss how protozoan parasites alter immature and mature B cell compartment. B1 and marginal zone (MZ) B cells, considered innate like B cells, are activated during protozoan parasite infections, and they generate short lived plasma cells providing a prompt antibody source. In addition, protozoan infections induce massive B cell response with polyclonal activation that leads to hypergammaglobulnemia with serum antibodies specific for the parasites and self and/or non related antigens. To protect themselves, the parasites have evolved unique ways to evade B cell immune responses inducing apoptosis of MZ and conventional mature B cells. As a consequence of the parasite induced-apoptosis, the early IgM response and an already establish humoral immunity are affected during the protozoan parasite infection. Moreover, some trypanosomatides trigger bone marrow immature B cell apoptosis, influencing the generation of new mature B cells. Simultaneously with their ability to release antibodies, B cells produce cytokines/quemokines that influence the characteristic of cellular immune response and consequently the progression of parasite infections.
27
ALGAILANY, Maryam, Sanaa ALHADIDI, and Abdul-Lateef MOLAN. "Iraqi household cockroaches collected from Diyala Province are potential vectors of medically-important parasites." Technium: Romanian Journal of Applied Sciences and Technology 18 (December 22, 2023): 92–103. http://dx.doi.org/10.47577/technium.v18i.10294.
Full textAbstract:
Household cockroaches constitute a significant public health threat due to their capacity of transmitting medically-important parasites and other pathogens. The role of Iraqi household cockroaches as potential vectors of medically-important parasites was evaluated in the present study. Fifty cockroaches (Periplaneta americana) were collected from different dwelling places of Baquba City, Diyala Province during the period from October to December 2022. The contents of their guts and external body surfaces were examined for the presence of medically-important parasites. The overall prevalence rate of parasitic infestation on the external body surfaces was 60.0%, while the overall prevalence rate of parasitic infection in the guts was 56.0%. Based on capture sites, cockroaches trapped in the toilets had more parasites than those caught from kitchens and rooms. Four species of medically important parasites were isolated from the external body surfaces of the cockroaches; three species were identified as protozoa and only one species was helminth. The protozoan parasites were identified as Blastocystis spp. (36.0%), Giardia spp. (14.0%) and Cryptosporidium spp. (4.0%). In addition, five species of medically important parasites were isolated from the gut contents; four species were identified as protozoa and only one species was helminth. The protozoan parasites were identified as Blastocystis spp. (24.0%), Giardia spp. (10.0%), Cryptosporidium spp. (8.0%), and Entamoeba histolytica/ E. dispar (2.0%). Enterobius vermicularis was the only helminth parasite isolated from both gut contents (2.0%) and external body surfaces (2.0%). In conclusion, the results showed that cockroaches were found to harbor intestinal parasites of public health importance and awareness on the potential role of these insects in the transmission of human intestinal parasites needs to be established
28
Kelsen, Anne, Robyn S. Kent, Anne K. Snyder, Eddie Wehri, Stephen J. Bishop, Rachel V. Stadler, Cameron Powell, et al. "MyosinA is a druggable target in the widespread protozoan parasite Toxoplasma gondii." PLOS Biology 21, no. 5 (May 8, 2023): e3002110. http://dx.doi.org/10.1371/journal.pbio.3002110.
Full textAbstract:
Toxoplasma gondii is a widespread apicomplexan parasite that can cause severe disease in its human hosts. The ability of T. gondii and other apicomplexan parasites to invade into, egress from, and move between cells of the hosts they infect is critical to parasite virulence and disease progression. An unusual and highly conserved parasite myosin motor (TgMyoA) plays a central role in T. gondii motility. The goal of this work was to determine whether the parasite’s motility and lytic cycle can be disrupted through pharmacological inhibition of TgMyoA, as an approach to altering disease progression in vivo. To this end, we first sought to identify inhibitors of TgMyoA by screening a collection of 50,000 structurally diverse small molecules for inhibitors of the recombinant motor’s actin-activated ATPase activity. The top hit to emerge from the screen, KNX-002, inhibited TgMyoA with little to no effect on any of the vertebrate myosins tested. KNX-002 was also active against parasites, inhibiting parasite motility and growth in culture in a dose-dependent manner. We used chemical mutagenesis, selection in KNX-002, and targeted sequencing to identify a mutation in TgMyoA (T130A) that renders the recombinant motor less sensitive to compound. Compared to wild-type parasites, parasites expressing the T130A mutation showed reduced sensitivity to KNX-002 in motility and growth assays, confirming TgMyoA as a biologically relevant target of KNX-002. Finally, we present evidence that KNX-002 can slow disease progression in mice infected with wild-type parasites, but not parasites expressing the resistance-conferring TgMyoA T130A mutation. Taken together, these data demonstrate the specificity of KNX-002 for TgMyoA, both in vitro and in vivo, and validate TgMyoA as a druggable target in infections with T. gondii. Since TgMyoA is essential for virulence, conserved in apicomplexan parasites, and distinctly different from the myosins found in humans, pharmacological inhibition of MyoA offers a promising new approach to treating the devastating diseases caused by T. gondii and other apicomplexan parasites.
29
Karpiyevich, Maryia, and Katerina Artavanis-Tsakonas. "Ubiquitin-Like Modifiers: Emerging Regulators of Protozoan Parasites." Biomolecules 10, no. 10 (October 3, 2020): 1403. http://dx.doi.org/10.3390/biom10101403.
Full textAbstract:
Post-translational protein regulation allows for fine-tuning of cellular functions and involves a wide range of modifications, including ubiquitin and ubiquitin-like modifiers (Ubls). The dynamic balance of Ubl conjugation and removal shapes the fates of target substrates, in turn modulating various cellular processes. The mechanistic aspects of Ubl pathways and their biological roles have been largely established in yeast, plants, and mammalian cells. However, these modifiers may be utilised differently in highly specialised and divergent organisms, such as parasitic protozoa. In this review, we explore how these parasites employ Ubls, in particular SUMO, NEDD8, ATG8, ATG12, URM1, and UFM1, to regulate their unconventional cellular physiology. We discuss emerging data that provide evidence of Ubl-mediated regulation of unique parasite-specific processes, as well as the distinctive features of Ubl pathways in parasitic protozoa. We also highlight the potential to leverage these essential regulators and their cognate enzymatic machinery for development of therapeutics to protect against the diseases caused by protozoan parasites.
30
Lauri, Natalia, Zaher Bazzi, Cora L. Alvarez, María F. Leal Denis, Julieta Schachter, Vanesa Herlax, Mariano A. Ostuni, and Pablo J. Schwarzbaum. "ATPe Dynamics in Protozoan Parasites. Adapt or Perish." Genes 10, no. 1 (December 27, 2018): 16. http://dx.doi.org/10.3390/genes10010016.
Full textAbstract:
In most animals, transient increases of extracellular ATP (ATPe) are used for physiological signaling or as a danger signal in pathological conditions. ATPe dynamics are controlled by ATP release from viable cells and cell lysis, ATPe degradation and interconversion by ecto-nucleotidases, and interaction of ATPe and byproducts with cell surface purinergic receptors and purine salvage mechanisms. Infection by protozoan parasites may alter at least one of the mechanisms controlling ATPe concentration. Protozoan parasites display their own set of proteins directly altering ATPe dynamics, or control the activity of host proteins. Parasite dependent activation of ATPe conduits of the host may promote infection and systemic responses that are beneficial or detrimental to the parasite. For instance, activation of organic solute permeability at the host membrane can support the elevated metabolism of the parasite. On the other hand ecto-nucleotidases of protozoan parasites, by promoting ATPe degradation and purine/pyrimidine salvage, may be involved in parasite growth, infectivity, and virulence. In this review, we will describe the complex dynamics of ATPe regulation in the context of protozoan parasite–host interactions. Particular focus will be given to features of parasite membrane proteins strongly controlling ATPe dynamics. This includes evolutionary, genetic and cellular mechanisms, as well as structural-functional relationships.
31
de Koning, Harry P. "Drug resistance in protozoan parasites." Emerging Topics in Life Sciences 1, no. 6 (December 22, 2017): 627–32. http://dx.doi.org/10.1042/etls20170113.
Full textAbstract:
As with all other anti-infectives (antibiotics, anti-viral drugs, and anthelminthics), the limited arsenal of anti-protozoal drugs is being depleted by a combination of two factors: increasing drug resistance and the failure to replace old and often shamefully inadequate drugs, including those compromised by (cross)-resistance, through the development of new anti-parasitics. Both factors are equally to blame: a leaking bathtub may have plenty of water if the tap is left open; if not, it will soon be empty. Here, I will reflect on the factors that contribute to the drug resistance emergency that is unfolding around us, specifically resistance in protozoan parasites.
32
Jimenez, Veronica, and Sebastian Mesones. "Down the membrane hole: Ion channels in protozoan parasites." PLOS Pathogens 18, no. 12 (December 29, 2022): e1011004. http://dx.doi.org/10.1371/journal.ppat.1011004.
Full textAbstract:
Parasitic diseases caused by protozoans are highly prevalent around the world, disproportionally affecting developing countries, where coinfection with other microorganisms is common. Control and treatment of parasitic infections are constrained by the lack of specific and effective drugs, plus the rapid emergence of resistance. Ion channels are main drug targets for numerous diseases, but their potential against protozoan parasites is still untapped. Ion channels are membrane proteins expressed in all types of cells, allowing for the flow of ions between compartments, and regulating cellular functions such as membrane potential, excitability, volume, signaling, and death. Channels and transporters reside at the interface between parasites and their hosts, controlling nutrient uptake, viability, replication, and infectivity. To understand how ion channels control protozoan parasites fate and to evaluate their suitability for therapeutics, we must deepen our knowledge of their structure, function, and modulation. However, methodological approaches commonly used in mammalian cells have proven difficult to apply in protozoans. This review focuses on ion channels described in protozoan parasites of clinical relevance, mainly apicomplexans and trypanosomatids, highlighting proteins for which molecular and functional evidence has been correlated with their physiological functions.
33
Gomes-Gonçalves, Sara, Sérgio Santos-Silva, Andreia V. S. Cruz, Clarisse Rodrigues, Vanessa Soeiro, Patrícia Barradas, and João R. Mesquita. "A Thorny Tale of Parasites: Screening for Enteric Protozoan Parasites in Hedgehogs from Portugal." Animals 14, no. 2 (January 21, 2024): 326. http://dx.doi.org/10.3390/ani14020326.
Full textAbstract:
Enteric protozoan parasites, such as Blastocystis sp., Balantioides coli, Cryptosporidium spp., and Giardia duodenalis, may have implications for both animal and human health.Transmitted through the fecal–oral route, these parasites cause symptoms such as diarrhea, abdominal pain, and weight loss. This study investigated the presence of these enteric protozoan parasites and genetically characterized them in hedgehogs from Portugal. A total of 110 hedgehog stool samples were collected. Molecular detection methods showed an overall occurrence of protozoa in 1.82% (2/110 95% CI: 0.22–6.41) of hedgehogs, with Blastocystis being found in one hedgehog and Cryptosporidium being found in another. No evidence for the presence of B. coli or G. duodenalis was found. This study suggests that there is a need to stay aware of hedgehogs as potential hosts of enteric protozoa. Ongoing research and surveillance efforts are recommended to explore practical prevention and control strategies. The results contribute to the limited knowledge of these parasites in Portuguese hedgehog populations and underscore their potential relevance to both veterinary and public health.
34
Abd AL-Khaliq, Israa Mohammad. "Review Article Blastocystosis." AL-Kindy College Medical Journal 15, no. 1 (September 5, 2019): 1–5. http://dx.doi.org/10.47723/kcmj.v15i1.63.
Full textAbstract:
Blastocystosis is symptomatic infection caused by the protozoal parasite Blastocystis , which resides in the intestinal tract of its hosts and it is one of the most common parasites reported in humans. It’s prevalence ranges between (30 - 50%) of the population in developing countries. This genus has a worldwide distribution and often the most commonly reported human intestinal protozoan in children and adults, even infect infants
35
Nabi, Saghar, Amir Ali Haji Seyed Javadi, Mahdi Vahid Balan, and Seyed Razi Bahavarnia. "The Effect of Tylosin Drug on Cryptosporidiosis in Stray Dogs of Tabriz and Its Importance in Public Health." International Journal of Medical Parasitology and Epidemiology Sciences 2, no. 4 (December 30, 2021): 103–6. http://dx.doi.org/10.34172/ijmpes.2021.27.
Full textAbstract:
Introduction: Intestinal protozoa of dogs have a relatively high diversity, and the prevalence of infection is often observed sub-clinically and sometimes clinically. Different species of Cryptosporidium are observed in the dog’s intestines. Due to the importance of pathogenicity of gastrointestinal protozoan parasites in dogs and also their zoonotic importance, this study was conducted on stray dogs in Tabriz. Methods: During this study, two hundred stool samples of stray dogs from different regions of Tabriz were prepared and examined microscopically for parasitology. The samples were tested by the Formalin-Ether concentration method, and also the following Ziehl-Neelsen modified staining method was used to observe Cryptosporidium protozoan. Results: Out of 200 fecal samples, 16 samples (8%) were infected with Cryptosporidium protozoa. Statistical analysis of the results also showed that there was a statistically significant difference in the rate of infection with protozoan parasites between dogs under one year old and dogs over one year old (P<0.05). Regarding the sex of dogs, there was a statistically significant difference in the prevalence of Cryptosporidium between male and female dogs (P<0.05). Sixteen dogs infected with Cryptosporidium parasite were also treated with tylosin for one week, and a decrease in infection with this parasite was observed in 9 treated dogs. Conclusion: In this study, the rate of Cryptosporidium infection in stray dogs decreased from 8% to 3.5% after tylosin treatment, and this drug may be useful in controlling this parasitic disease in dogs, but more extensive research should be carried out to eradicate this parasite in dogs.
36
Howells, R. E. "The modes of action of some anti-protozoal drugs." Parasitology 90, no. 4 (April 1985): 687–703. http://dx.doi.org/10.1017/s0031182000052318.
Full textAbstract:
In spite of the continuing need for new and improved anti-protozoal drugs for use in man, a considerable contraction of industrially based research on anti-protozoal drugs has occurred in recent years. Newton (1983) reviewed the reasons for this decline and presented a compelling argument that fundamental research on the biology of the parasites is essential for the discovery of leads for the development of a new generation of drugs – a rational chemotherapy. The rapid advance in knowledge of the biochemistry of parasitic protozoa which has occurred in recent years has provided a number of potential leads to new drug development and has permitted a greater understanding of the mode of action of many current drugs. The account of these advances which follows is necessarily selective and relates to protozoan parasites of man.
37
OLIVEIRA, Raylene Andrade, Rodrigo GURGEL-GONÇALVES, and Eleuza Rodrigues MACHADO. "Intestinal parasites in two indigenous ethnic groups in northwestern Amazonia." Acta Amazonica 46, no. 3 (September 2016): 241–46. http://dx.doi.org/10.1590/1809-4392201505883.
Full textAbstract:
ABSTRACT Approximately 90% of the population in the northwestern Amazonia is composed of indigenous people and their healthcare is still a challenge. The objective of this study was to determine the frequency of parasites in two indigenous ethnic groups (Baré and Baniwa) in northwestern Amazonia. Stool samples from 270 individuals (199 Baniwa and 71 Baré) were analyzed using Richie's method and the spontaneous sedimentation method. Statistical differences among the proportions of infected individuals based on gender, age, and ethnicity were determined. All individuals were infected by protozoans or helminths. The most frequent parasites in the indigenous people were Ascaris lumbricoides (73%), Entamoeba spp. (53%), and Giardia intestinalis (48%). Protozoan parasites were more common among children aged 0-12 years; however, the frequency of helminths, such as hookworms and A. lumbricoides, was higher in adults. There were no significant differences in parasite frequencies between different genders or ethnic groups. Mixed infections by two or more protozoan and/or helminth species were detected in 96% of individuals. One individual was infected by 14 species. A high frequency of intestinal parasites was found in Baré and Baniwa ethnic groups. Improvements to infrastructure and health education programs are required to reduce risk of infection by intestinal parasites.
38
Alyasiri, Ali Jawad, and Mohammed Qasim Waheeb. "Global overview of Leishmania virulence factors, and the role of GP63 in promastigotes." Science Archives 03, no. 02 (2022): 124–32. http://dx.doi.org/10.47587/sa.2022.3208.
Full textAbstract:
Protozoa parasites of the genus Leishmania have a great ability to avoid damage in the hostile environments they encounter throughout their life cycle within the host’s body. Parasites have developed many virulence factors to ensure their persistence and replication within the host, and the first role of these factors is to attenuate the host’s defenses against them through innate and adaptive immunity, as evidence indicates that the determinants of parasite virulence are responsible for evading the host’s defenses, allowing these organisms to survive on Alive in the host’s hostile immune environment. Understanding the molecular details of how these pathogens persist with impunity under extreme conditions is beginning to begin. The fact that Leishmania parasites have adapted not only to survive but are likely to reproduce is due to the protection afforded by specialized molecules on the parasite’s cell surface. Although recent years have seen clear and significant progress in the research on Leishmania in different directions, many issues have yet to be clarified. The surface of all parasites, especially protozoa, usually undergoes pronounced changes during their life cycle. It is of particular interest in the case of protozoan parasites of the genus Leishmania whose surface is exposed to different and hostile environments within vertebrate and invertebrate organisms. Because of the importance that the cell surface of pathogenic parasites plays in their interaction with the host for survival, some efforts have been devoted to their characterization. This review aims to give an overview of the main virulence factors that contribute to parasite survival and survival. We have attempted to provide a brief picture of the factors that influence the interaction of the parasite in its host, further highlighting GP63 as a critical virulence factor affecting macrophage physiology as well as the functioning of the immune system.
39
C. Roy, S. R. Dey, and B. Bhowmik. "Freshwater fish parasite diversity in West Bengal – A review." Ecology, Environment and Conservation 29, no. 01 (2023): 161–69. http://dx.doi.org/10.53550/eec.2023.v29i01.026.
Full textAbstract:
Aquaculture has the potential to meet the need of growing demand of fish in an affordable price. But in capture and in culture fisheries the fishes face diseases that interfere in the production of fish. The occurrence of disease causes the reduced production in aquaculture or reduce the marketable value of fish because of change of flesh quality, thus hampering the production. Freshwater fishes whether they are cultured or wild face different types of diseases in their skin, gills, fins, blood, and internal organs. The parasites that cause the diseases may be protozoans or metazoans.The main protozoan freshwater fish diseases are ichthyophthiriasis, trichodiniasis, costiosis, chilodonellosis. The most common metazoan parasitic diseases of freshwater fishes are dactylogyrusis, gyrodactylosis, argulosis, myxosporidiasis, ligulosis, ergasilosis, lernaesis, etc. The focus of this review is to screen the research studies that takes place on freshwater fish parasites of West Bengal. The review also aims to study the diversity of freshwater fish parasites in West Bengal, so that it will helps the researcher to get an idea about the freshwater fish parasites and their mode of infection in the fishes. The research work that takes place in different regions of West Bengal. Some of them reveal new species of parasites in fishes. Protozoan, cnidarian, acanthocephalan, nematode, cestode, trematode, crustacean parasites are identified in freshwater fishes of West Bengal. Among the protozoans cailiates, flagellates are identified. Trichodinids are very common protozoan fish parasites in most districts. Parasites under genus Myxobolus, Dactylogyrus, Gyrodactylus, Argulus, Lernea are common among the metazoans.
40
Girmaye, Diriba, Akinaw Wagari, and Teshita Edaso Beriso. "Identification of major protozoal enteropathogens causing calf diarrhea in dairy farms in and around Holeta Town, Oromia Special Zone, Ethiopia." Ethiopian Veterinary Journal 28, no. 1 (March 18, 2024): 139–48. http://dx.doi.org/10.4314/evj.v28i1.9.
Full textAbstract:
Calf diarrhea can be caused by a variety of pathogens, including bacteria, viruses, protozoa, and intestinal parasites. Giardia, Eimeria, and Cryptosporidium are the most significant protozoan parasites and are all individually and ollectively infectious. A case-series study was carried out in and around Holeta dairy farms, Oromia Special Zone, Ethiopia, from November 2017 to April 2018 to identify the main protozoan enteropathogens from diarrheic calves. Samples were purposely collected from three dairy farms: Serkalem Dairy Farm (SDF), Holeta Agricultural Research Centre (HARC), and Ada Berga Agricultural Research Centre (ABARC). A total of 93 fecal samples were taken from diarrheic calves of up to 4 months of age. Protozoan enteropathogens were identified using flotation and modified Ziehl Neelsen staining methods. Cryptosporidium, Eimeria, and Giardia were detected in 44 (47.3%), 50 (53.8%), and 34 (36.6%) of the diarrheic fecal samples examined, respectively. The findings indicated that there were 17 (18.27%) cases of Cryptosporidium, Eimeria, and Giardia as mixed infections, 16 (17.2%) cases of Cryptosporidium and Eimeria, 5 (5.4%) cases of Cryptosporidium and Giardia, and 4 (4.3%) cases of Eimeria and Giardia, compared to 13 (13.97%), 6 (6.45%), and 5 (5.4%) cases of Cryptosporidium, Eimeria and Giardia as single infections, respectively. The selected farms had significant prevalence levels of three common protozoa: Eimeria, Giardia, and Cryptosporidium. Further molecular research is required to identify the species and genotype levels of protozoal enteropathogens and related risk factors.
41
Coppens, Isabelle. "Metamorphoses of malaria: the role of autophagy in parasite differentiation." Essays in Biochemistry 51 (October 24, 2011): 127–36. http://dx.doi.org/10.1042/bse0510127.
Full textAbstract:
Several protozoan parasites undergo a complex life cycle that alternates between an invertebrate vector and a vertebrate host. Adaptations to these different environments by the parasites are achieved by drastic changes in their morphology and metabolism. The malaria parasites must be transmitted to a mammal from a mosquito as part of their life cycle. Upon entering the mammalian host, extracellular malaria sporozoites reach the liver and invade hepatocytes, wherein they meet the challenge of becoming replication-competent schizonts. During the process of conversion, the sporozoite selectively discards organelles that are unnecessary for the parasite growth in liver cells. Among the organelles that are cleared from the sporozoite are the micronemes, abundant secretory vesicles that facilitate the adhesion of the parasite to hepatocytes. Organelles specialized in sporozoite motility and structure, such as the inner membrane complex (a major component of the motile parasite's cytoskeleton), are also eliminated from converting parasites. The high degree of sophistication of the metamorphosis that occurs at the onset of the liver-form development cascade suggests that the observed changes must be multifactorial. Among the mechanisms implicated in the elimination of sporozoite organelles, the degradative process called autophagy contributes to the remodelling of the parasite interior and the production of replicative liver forms. In a broader context, the importance of the role played by autophagy during the differentiation of protozoan parasites that cycle between insects and vertebrates is nowadays clearly emerging. An exciting prospect derived from these observations is that the parasite proteins involved in the autophagic process may represent new targets for drug development.
42
Tsai, Yu-Hsuan, Maurice Grube, Peter H. Seeberger, and Daniel Varon Silva. "Glycosylphosphatidylinositols of Protozoan Parasites." Trends in Glycoscience and Glycotechnology 24, no. 140 (2012): 231–43. http://dx.doi.org/10.4052/tigg.24.231.
Full text
43
Jain, Maneesh. "Mucins in protozoan parasites." Frontiers in Bioscience 6, no. 1 (2001): d1276. http://dx.doi.org/10.2741/jain.
Full text
44
Kent, M. L., J. Lom, I. Dyková, and I. Dykova. "Protozoan Parasites of Fishes." Journal of Parasitology 79, no. 5 (October 1993): 673. http://dx.doi.org/10.2307/3283600.
Full text
45
Lopes, Marcela F., Dario S. Zamboni, Hugo D. Lujan, and Mauricio M. Rodrigues. "Immunity to Protozoan Parasites." Journal of Parasitology Research 2012 (2012): 1–3. http://dx.doi.org/10.1155/2012/250793.
Full text
46
Miyake, Yuko, Panagiotis Karanis, and Shoji Uga. "Cryopreservation of protozoan parasites." Cryobiology 48, no. 1 (February 2004): 1–7. http://dx.doi.org/10.1016/j.cryobiol.2003.10.004.
Full text
47
Patterson, Jean L. "Viruses of protozoan parasites." Experimental Parasitology 70, no. 1 (January 1990): 111–13. http://dx.doi.org/10.1016/0014-4894(90)90091-p.
Full text
48
Batra, Surinder K. "Mucins in protozoan parasites." Frontiers in Bioscience 6, no. 3 (2001): d1276–1283. http://dx.doi.org/10.2741/a680.
Full text
49
Thulin, Jan. "Protozoan parasites of fishes." Parasitology Today 10, no. 1 (January 1994): 41. http://dx.doi.org/10.1016/0169-4758(94)90359-x.
Full text
50
Sharma, Anuja, Shilpa Sharma, Shilippreet Kour, Achhada Ujalkaur Avatsingh, Kahkashan Perveen, Jamilah A. Alsulami, and Nasib Singh. "Gastrointestinal Nematodes and Protozoa in Small and Large Ruminants from Rural Agro-Climatic Regions of Northern India." Diversity 15, no. 11 (November 4, 2023): 1131. http://dx.doi.org/10.3390/d15111131.
Full textAbstract:
Gastrointestinal nematode parasites and gastrointestinal protozoan parasites are considered detrimental to the livestock population and manifest production-limiting effects. Small and large ruminants (cattle, buffalo, goats, and sheep) are important components of the rural economy of northern India. However, the epidemiology of gastrointestinal parasites in this agro-climatic region has not been studied extensively. In this study, the prevalence of gastrointestinal parasites was determined in 163 animals, including cattle (n = 86), buffalo (n = 11), goats (n = 48), and sheep (n = 18) from 26 sampling sites by copro-parasitological analysis. The prevalence values of 94.47% and 66.87% were recorded for the nematodes and protozoa, respectively. The group-wise prevalence of gastrointestinal nematode parasites was 95.3%, 90.9%, 93.7%, and 94.4% in cattle, buffalo, goats, and sheep, respectively, whereas for gastrointestinal protozoan parasites, the respective values were 70.9%, 54.5%, 60.4%, and 72.2%. Copromicroscopy revealed ten genera of nematodes—Ascaris, Capillaria, Cooperia, Haemonchus, Nematodirus, Oesophagostomum, Ostertagia, Strongyloides, Trichostrongylus, Trichuris, and one protozoan genus—Eimeria. The prevalence of Trichostrongylus spp. was highest in buffaloes, whereas in cattle, Ascaris spp. were predominant. In both goats and sheep, Haemonchus contortus was found to be predominant. The highest prevalence of gastrointestinal parasites was recorded in the rainy season. These findings indicate the prevalence of gastrointestinal parasites in the ruminant population in this region and necessitate the implementation of preventive and control strategies for effective animal health management.