Dissertations / Theses: 'Prunella'

1

Langmore, Naomi Elisabeth. "Song and the variable mating systems of the dunnock Prunella modularis and the alpine accentor Prunella collaris." Thesis, University of Cambridge, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.360002.

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Byle, Philip Andrew Frank. "Behaviour and ecology of the dunnock, Prunella modularis." Thesis, University of Cambridge, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.330150.

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Fang, Xuya. "Characteristics of extracts from Prunella vulgaris on the immune response of monocytes/macrophages." Click to view the E-thesis via HKUTO, 2004. http://sunzi.lib.hku.hk/hkuto/record/B31325105.

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Fang, Xuya, and 方旭亞. "Characteristics of extracts from Prunella vulgaris on the immune response of monocytes/macrophages." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2004. http://hub.hku.hk/bib/B31325105.

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Sack, Peter. "Ausbreitungsbiologische Experimente an Arten der Subtribus Prunellineae (Prunella L. und Cleonia L.; Lamiaceae) /." Stuttgart : Schweizerbart, 2003. http://catalogue.bnf.fr/ark:/12148/cb39146359j.

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Laporte-Cru, Jean. "Contribution à l'étude biosystématique du genre Prunella L. : hybridation et évolution taxonomique de P. vulgaris L. et P. laciniata L." Paris 11, 1989. http://www.theses.fr/1989PA112078.

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La première partie consiste en une étude taxonomique de l'espèce Prunella vulgaris. Différentes méthodes numériques appliquées à des populations sauvages du Sud-Ouest de la France permettent de séparer des groupes de populations grâce à des caractères discriminants et de déterminer leur valeur toxonomique. La culture expérimentale permet de préciser l'influence du milieu sur les caractères morphologiques. La deuxième partie est consacrée à l'étude de l'hybride entre P. Vulgaris et P. Laciniata. Après une description des différentes formes sauvages, la mise en culture de certaines permet d'étudier leur descendance et d'obtenir des lignées pures. L'évolution naturelle au cours des années successives est retracée pour quelques stations. Dans la troisième partie, nous avons recherché les mécanismes assurant le maintien des deux espèces parentes, compte tenu de leur facilité à s'hybrider. L'étude phytosociologique montre qu'il existe un certain isolement écologique entre les deux espèces. Les diverses modalités de fécondation et la phénologie sont ensuite envisagées sur des populations cultivées des deux espèces parentales et hybrides. Enfin, l'hybridation expérimentale nous a permis de reproduire des types naturels et de comparer la fertilité et les caractères phénologiques des hybrides suivant le sens du croisement.

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Goronga, Tinopiwa. "The synthesis of analogs of Tamiflu via a [3+3] annulation and biological activity of Prunella vulgaris." [Ames, Iowa : Iowa State University], 2006.

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8

Blomqvist, Elin. "Effekter av osmotisk potential, samt salteffekter på några vägkantsväxter." Thesis, Karlstads universitet, Institutionen för miljö- och livsvetenskaper (from 2013), 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:kau:diva-67635.

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Syftet med studien var att undersöka effekter på frögroning i form av procentuell frögroning och mean germination time (MGT) för några vanligt förekommande vägkantsväxter till följd av saltning av vägar. Frön från (Prunella vulgaris), getväppling (Anthyllis vulneraria), grått saltgräs (Puccinella distans), grässtjärnblomma (Stellaria graminea) och tjärblomster (Viscaria vulgaris) fördelades i petriskålar och utsattes för mannitol- och natriumkloridlösningar av osmotisk potential -0,3, -0,6 och -0,9 MPa. Mannitol användes för att skilja osmotiska effekter från joniska effekter som natriumklorid ger upphov till. Kontroller med avjoniserat vatten visade frögroning i frånvaro av osmotiska- och joniska effekter. Den procentuella frögroningen var högst i kontrollerna för samtliga arter och minskade med en lägre osmotisk potential. Tjärblomster visade sig gro bäst under samtliga behandlingar. Lägst procentuell groning hade grått saltgräs och grässtjärnblomma. Det tog längre tid för alla arter att gro under en lägre osmotisk potential. Tjärblomster och getväppling visade sig mest känsliga mot abiotiska förändringar och grodde långsammast i förhållande till kontroller för respektive art. Vilket ämne som fröna utsattes för hade ingen påverkan på procentuell groning och MGT, vilket tyder på att det är osmotiska effekter som påverkar arternas frögroning. The aim of this study was to investigate effects of lowered osmotic potential and osmotic agents on seedling germination and mean germination time (MGT) of some common roadside plants. Seeds of Prunella vulgaris, Anthyllis vulneraria, Puccinella distans, Stellaria graminea and Viscaria vulgaris were distributed in petri dishes and exposed to mannitol and sodium chloride solutions with osmotic potential of -0.3, - 0.6 and -0.9 MPa. Mannitol was used to distinguish osmotic effects from ionic effects caused by sodium chloride. Controls with distilled water showed germination in the absence of osmotic and ionic effects. The percentage of emerged seedlings were highest in controls for all species and decreased with a lower osmotic potential. Viscaria vulgaris had the highest percentage of emerged seedlings across all treatments. The lowest percentage of emerged seedlings had Puccinella distans and Stellaria graminea. It took longer time for all species to germinate under a lower osmotic potential. Viscaria vulgaris and Anthyllis vulneraria turned out to be most sensitive to abiotic changes and grew slowest in relation to controls. There was no difference in the impact of the osmotic agent on percentage germination and MGT, indicating that it is mainly the osmotic effect that affects the seed germination.

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Arlot, Christine. "Contribution à l'étude des groupements préforestiers du centre-sud du Bassin Parisien : essai de synthèse sur les Prunetalia spinosae Tx. 52 des domaines atlantiques et médioeuropéen." Paris 11, 1985. http://www.theses.fr/1985PA112386.

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Cette thèse consiste en l’étude phytosociologique des groupements préforestiers (fourrés et manteaux) de la Beauce, de la Sologne et des régions voisines. La végétation a été étudiée selon les principes de la méthode sigmatiste. Une attention particulière a été portée sur les problèmes méthodologiques liés à l’étude de ces groupements (aire minimale…) ainsi que sur les problèmes taxonomiques (détermination des Rubus et des Rosa). Des analyses numériques ont été utilisées pour le traitement des données. Sept groupements ont été décrits ; leurs caractères écologiques, dynamiques et chorologiques sont précisés. Une nouvelle sous-association a été mise en évidence pour le centre de la Beauce. Les données régionales ont ensuite été intégrées dans une analyse générale des groupements des Prunetalia spinosae Tx. 52 d’Europe moyenne. La prise en compte de de 3800 relevés de la bibliographie a permis de proposer une nouvelle structuration de cet ordre en tenant compte de l’intégration des groupements limitrophes, tant du point de vue géographique (groupements du sud de l’Europe et d’Europe de l’est) que du point de vue dynamique (groupements à Rubus, groupements succédant à la lande). L’étude de l’alliance du Berberidion a été particulièrement approfondie. Cette alliance, complexe, comprenant des groupements de plaine et des groupements montagnards, pourrait être élevée au rang de sous-ordre (les Berberidenalia). Les groupements préforestiers se sont avérés être particulièrement révélateurs des limites des secteurs bioclimatiques. Leur répartition est aussi fortement corrélée aux variations du climat régional, dans la mesure où ceux-ci sont définis au niveau le plus fin (sous association).

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Cheng, Chieh Lun, and 鄭傑倫. "Exploring Neutrophil Elastase Inhibitors from Prunella vulgaris." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/4eq874.

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碩士 長庚大學 中醫學系天然藥物 106 Acute lung injury (ALI) is clinically characterized as a respiratory failure syndrome. Previous studies have shown that the neutrophils infiltration in lung tissue is one of the pathologic features. It has been reported that human neutrophil elastase (HNE) is highly correlated to the severity of ALI. As a result, the inhibitor of HNE has become an important study interest in ALI. In our previous study, we examined the serine protease activity in 75 traditional Chinese medicines in which we found Prunella vulgaris (PV) an ideal candidate that processes the characteristic of HNE inhibition (IC50, 8.08 ± 1.28 g/ml) .This study focus on isolating the bioactive fraction that significantly inhibit HNE in Prunella vulgaris via the bioactivity-guided fractionation. Its qualitative and quantitative characteristics are also investigated. Our results indicate that PVAP, the acidic insoluble bioactive fraction with the molecular weight is between 100 kDa and 300 kDa extracted from Prunella vulgaris, shows the ability in selective inhibition of HNE (IC50, 2.42 ± 0.19 g/ml). PVAP consists of carbohydrate, protein and uronic acid of 11.94 %, 17.07 % and 15.61 % respectively. In addition, the monosaccharides composition analysis reveals that PVAP contains mannose、rhamnose、galacturonic acid、glucose、xylose、arabinose in molar ratio of 1.000：0.999：1.592：1.605：2.049：0.742：1.040, respectively. In our animal experiments, the results show that PVAP protect mice from lipopolysaccharide-induced ALI by reducing pulmonary edema, myeloperoxidase and elastase activity, neutrophil infiltration, pro-inflammatory cytokines, and neutrophil extracellular traps formation. These results suggested that PVAP alleviate ALI from LPS as a HNE inhibitor. It also demonstrates its potential in pharmaceutical development in prevention of ALI.

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Neugebauerová, Jarmila. "Introdukce druhu Prunella vulgaris L. (černohlávku obecného) mezi pěstované léčivé rostliny." Doctoral thesis, 2004. http://www.nusl.cz/ntk/nusl-92164.

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12

Yeh, Szu-Chien, and 葉思見. "Studies on the Tyrosinase Activity Enhancing Constituents of Prunella vulgaris L." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/40564411898062901973.

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碩士 靜宜大學 應用化學系研究所 91 In our continuing search for natural source ingredient from Chinese medicinal herbs, was found that extracts of Prunella vulgaris L. showed the significant tyrosinase enhancing activity. In this study, the active constituent of Prunella vulgaris L. was isolated by the process of tyrosinase activity assay and column chromatography. The structure was elucdiate by the spectroscopic methods and its activity was also achieved.

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Chen, Chia-hua, and 陳嘉慧. "Population differentiation and phylogeography of Prunella vulgaris L. subsp. asitiaca in Taiwan." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/61407913496310952716.

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碩士 國立臺南大學 材料科學系自然科學教育碩士班 96 Prunella, a genus of the Lamiaceae, is distributed in Africa, Asia, Europe, and North America, about 15 species. One species, P. vulgaris subsp. asitiaca, is distributed from seashores to high mountains at elevation of 3600 meters in Taiwan. The noncoding region sequences of the atpB-rbcL and trnL-trnF region of the chloroplast genome were used to conduct the phylogeographical study of P. vulgaris subsp. asitiaca in Taiwan. The cpDNA atpB-rbcL noncoding region had 905bp after alignment. Among these sequences, the amount of polymorphic sites was 18, nucleotide diversity was 0.00477, and haplotype diversity was 0.850±0.026. The cpDNA trnL-trnF noncoding region had 817 bp after alignment. Among these sequences, the amount of polymorphic sites was 26, nucleotide diversity was 0.00324, and haplotype diversity was 0.794±0.029. The low nucleotide diversity and high haplotype diversity indicated that species has suffered the bottleneck effect or the founder effect. During a period of time to propagate and colonize, the population has accumulated enough variations to increase the haplotype diversity. P. vulgaris subsp. asitiaca var. asiatica distributed from seashore to medium mountain area and P. vulgaris subsp. asitiaca var. nanhutashanensis distributed in high mountain area are not only different in morphology but also different in molecular data. Using the likelihood methodology to estimate the coalescent time, P. vulgaris subsp. asitiaca immigrated about 0.41-0.67 million years ago. In the beginning, it might immigrate to North Coast, and then southward colonized.

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Huang, Wei Ling, and 黃韋伶. "Studies on the Chemical and Bioactive Constituents of Endophytic Penicillium paxilli from Prunella vulgaris Linn." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/29984198720622740899.

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碩士 長庚大學 中醫學系天然藥物 101 In our previous study, the endophytes Penicillium paxilli was isolated from Prunella vulgaris Linn. The chloroform extract of Penicillium paxilli fermention liquid showed cytotoxicity effect on Hep G2, Hep 3B, MCF-7 with IC50 values 0.50,14.87 and 11.34 M respectively. The aim of study is to isolate the bioactive and chemical compounds. According to the result, ten compounds were isolated : 8-mthoxynaphthalene-1-ol (1), paxilline (2), 1,8-dimethoxynaphthalene (3), pyrenocine E (4), pyrenocine A (5), pyrenocine B (6), citreothiopyrane A (7), penipaxine (8), 5α,8α-epidioxyergosta-6,22-dien -3β-ol (9), 1,8-dihydroxynaphthalene (10). Besides, citreothiopyrane A (7), penipaxine (8) are new compounds. pyrenocine A (5) showed cytotoxicity effect on PC-3, SK-Hep-1 and TOV-21G-RT with IC50 values 1.75, 2.61, 0.56 . pyrenocine E (4) also showed cytotoxicity effect on PC-3, TOV-21G-RT with IC50 values 9.45, 5.39 μM.

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"Studies on the anti-herpes simplex virus (HSV) constituents from a Chinese herbal medicine, prunella vulgaris." 2003. http://library.cuhk.edu.hk/record=b6073514.

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Zhang Yongwen. "February 2003." Thesis (Ph.D.)--Chinese University of Hong Kong, 2003. Includes bibliographical references (p. 174-188). Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web. Electronic reproduction. Ann Arbor, MI : ProQuest Information and Learning Company, [200-] System requirements: Adobe Acrobat Reader. Available via World Wide Web. Mode of access: World Wide Web. Abstracts in English and Chinese.

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Chiu, Pin-Siang, and 邱品翔. "Studies on the Three Elements of Fertilizer for Growth,Yield and Components Analysis in Prunella vulgaris L." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/ndux8q.

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碩士 國立屏東科技大學 農園生產系所 105 Prunella vulgaris L. is a perennial herb of Prunella in the Lamiaceae. And the components include phenolics acids, flavonoids, and terpenoids, etc. Studies have pointed out that in modern clinical and more for lowering blood pressure, inhibit and prevent the formation of cancer cells, and also has anti-bacterial, anti-infection and immune system regulation. In this study, effects of the three major fertilizer elements (Control (CK), Full applying fertilizer (NPK), Applying without nitrogen fertilizer (PK), Applying without phosphate fertilizer (NK), Applying without Potassium fertilizer (NP)) on growth, yield as well as analysis on active components in P. vulgaris at different harvesting time and spica. Studies also conducted on optimal extraction methods for six active components and determination of their contents by HPLC (High performance liquid chromatography). As the results, P. vulgaris is applied ammonium sulfate, calcium Phosphate And potassium chloride were 350,150 and 180 kg/ha, respectively. The agronomic traits of their growing conditions reached their peak in August, followed by a gentle growth trend. The optimum yield of P. vulgaris treated with NPK were 54.21 ± 15.69 g and cluster yield were 13.8 g/plant in August. Extracted with 50% methanol by ultrasonic extraction methods showed that, the amount of components in chlorogenic acid, caffeic acid, rutin, rosmarinic acid, quercetin, and kaempferol were 5.19 ± 8.13, 47.53 ± 9.10, 241.47 ± 66.12, 681.11 ± 159.41, 107.40 ± 3.60 and 128.80 ± 2.42 µg/g, respectively. The components in spica were 1.10 ± 0.23, 109.87 ± 0.36, 18.93 ± 2.57, 310.61 ± 23.35 and 7.44 ± 0.38 µg/g, respectively. Kaempferol is not measured on the spica. In general the three major fertilizer elements were effects of yield and spica yield on P. vulgaris. The yield from NPK treatment was the highest, in the CK and PK treatment under the best content.

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HUANG, CHUNG-YUEH, and 黃中岳. "1. The effect of aqueous extract of Prunella vulgaris in suppressing invasion and migration in human non-small cell lung cancer cells. 2. Identification of novel small chemicals with autophagic clearance of polyglutamine aggregation in human neuroblastoma cells." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/51288579547742351837.

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碩士 國立臺灣師範大學 生命科學研究所 100 1. Cancer cells grow and duplicate unregulated that form malignant tumors. The capability of cell invasion and migration from the origin site (metastasis) to nearby parts is the most threating. Cancer metastasis starts with the degradation of extracellular matrix (ECM). Both invasion to nearby tissue of cancer cell and inducement to angiogenesis relies on the matrix metalloproteinase (MMP) activity for ECM degradation. The thesis focused on treating cell lines, A549 (wild type p53 human adenocarcinoma), H460 (human large cell lung carcinoma) and H1299 (p53 deleted human adenocarcinoma) with Chinese herb medicine (CHM), and then detect changes of MMP-9 and MMP-2 activities by evaluating gelatin zymography. Both gelatin zymography and western blot to find out whether CHM can inhibit the MMP-9 and MMP-2 expression. The work is also to figure out whether MMP-9 and MMP-2 inhibition affects the migration and invasion capacity of the cancer cells. We have found that the aqueous extract of Prunella vulgaris can affects MMP-9 and MMP-2 activities in human lung carcer cells, and inhibit the invasion and migration of cancer cells. The other goal of this thesis is to find out new CHM‘s that are capable of inhibiting tumor angiogenesis and metastasis by evaluating MMP-9 and MMP-2 activities in human hepatocarcinoma cells. 2. Cells digest unwanted substance by autophagy, a procedure that could reuse building blocks from unwanted substances and clarify poisonous substance. The recycled substrate is covered by lipid bilayer, forming autophagsome that combines lysosome for digestion. Polyglutamine (polyQ) disease is a set of genetic disorder caused by the increased numbers of CAG or CUG repeats in some neurodegenerative diseases. Drugs that induced up-regulation of autophagy have been proved decrease the toxicity of polyQ aggregation in mouse model of Huntington’s disease. Thus, the autophagy-inducing drugs promise to be an effective therapy of polyQ diseases. The thesis used SK cell lines transfected with green fluorescent protein conjugated with different length of polyQ. The purpose is to find out whether the autophagsome can be increased by treatment of different compounds and whether they affect the viabilities of the cells. Three compounds were found capable of inducing cell autophagy and decreasing polyQ aggregration in cell models. In the future, the research will focus on how the selected drugs affect autophagy and test the drugs in animal model.

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Dissertations / Theses on the topic 'Prunella'

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