Academic literature on the topic 'Psappha'

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Journal articles on the topic "Psappha"

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Hunt, Edmund. "Psappha, 3x3 Concerts 1 October and 12 November 2020." Tempo 75, no. 296 (2021): 89–90. http://dx.doi.org/10.1017/s0040298220001187.

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What constitutes a concert? While many have played with the form, the basics – performers and audience in a shared space – seemed self-evident. However, at a time when restrictions limit or prevent gatherings of performers and audience, this question has assumed new significance. Indeed, the area of live music performance has borne the brunt of many of the ongoing uncertainties, changes and debates of recent months. In the midst of disappointing and unsettling news about cancellations and postponements, it was a welcome relief to read that Psappha decided to go ahead with their 2020–21 concert series. As one of the UK's preeminent contemporary music ensembles, Psappha's influence extends far beyond its Manchester home, reaching a worldwide audience via its YouTube channel. Psappha's current programme is testament to the ensemble's vision, juxtaposing well-known monoliths from the twentieth-century repertoire against works by emerging composers and those whose music is heard less often in the UK.
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Venn, Edward. "Peter Maxwell Davies new and classic." Tempo 59, no. 233 (2005): 79–80. http://dx.doi.org/10.1017/s0040298205260254.

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MAXWELL DAVIES: Miss Donnithorne's Maggot; Eight Songs for a Mad King. Jane Manning (sop), Kelvin Thomas (bar), Psappha. PSA CS 1001MAXWELL DAVIES: Naxos Quartets Nos. 1 and 2. Maggini Quartet. Naxos 8.557396
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Mottershead, Tim. "Manchester University: Psappha in Klas Torstensson's Violin Concerto." Tempo 67, no. 265 (2013): 80–81. http://dx.doi.org/10.1017/s0040298213000545.

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You're probably wondering why a violin concerto was given its UK première by the chamber ensemble Psappha? An informative programme note by Paul Griffiths for the 15 February concert revealed that Swedish composer Klas Torstensson (b. 1951) had in fact written a much longer, though still compactly scored, work in 2010 and had ‘squashed it down’ in length and further reduced the number of players. The work's full title is Pocket Size Violin Concerto – scored for soloist with unconducted accompaniment from piano, flute, and cello. Whilst compression of this kind is not uncommon in other branches of the arts, and concision is a noble artistic aim, one's fear was that such drastic pruning might have short-circuited the music's arguments. Happily this proved unfounded; and whilst the original half-hour's duration might have been pushing it a bit, the modified version (at a whisker under 17 minutes) seemed just about right.
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Conway, Paul. "Manchester, Cosmo Rodewald Concert Hall: Gordon Crosse's L'enfant sauvage." Tempo 67, no. 266 (2013): 76–78. http://dx.doi.org/10.1017/s0040298213000910.

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Contemporary music ensemble Psappha gave three world premières in a concert at the University of Manchester's Cosmo Rodewald Hall on 8 March 2013. Their programme began with first performances of brief works by two young composers connected with the University. I Lost My Way in Dixieland, by Thomas Jarvis (b.1991), was a deftly realized deconstruction and reinvention of a popular jazz style, with a throwaway ending that made an apt parting gesture for a witty and enjoyable pastiche. And Sempadan, by Sayyid Shafiee (b.1987), made effective use of offstage trumpet and trombone interacting with on-stage clarinet, percussion and double bass, to suggest the concept of two different but complementary cultures.
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Smith, Neil Thomas. "David Fennessy - David Fennessy: Panopticon. Ensemble Modern, Psappha, Münchener Kammerorchester, Hebrides Ensemble. NMC, NMCD244." Tempo 73, no. 290 (2019): 84–85. http://dx.doi.org/10.1017/s0040298219000640.

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Hughes, Bernard. "Kenneth Hesketh - KENNETH HESKETH: A Rhyme for the Season1; Ein Lichtspiel (after Moholy-Nagy)2; Graven Image1; Wunderkammer(konzert)2; At God speeded summer's end1. 1Royal Liverpool Philharmonic Orchestra c. Christoph-Mathias Mueller, 2Ensemble 10/10 c. Clark Rundell. NMC D186. - KENNETH HESKETH: De Destini Incrociati; Aphorisms; Fra Duri Scogli; Three pieces in the shape of a shoe; Theatre of Attractions. Psappha c. Nicholas Kok. Psappha B00AUKGHM0M." Tempo 67, no. 265 (2013): 109–10. http://dx.doi.org/10.1017/s0040298213000703.

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Wang, Shanshan, Taiga Ichinomiya, Yuki Terada, Dongsheng Wang, Hemal H. Patel, and Brian P. Head. "Synapsin-Promoted Caveolin-1 Overexpression Maintains Mitochondrial Morphology and Function in PSAPP Alzheimer’s Disease Mice." Cells 10, no. 9 (2021): 2487. http://dx.doi.org/10.3390/cells10092487.

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Mitochondrial dysfunction plays a pivotal role in the Alzheimer’s Disease (AD) pathology. Disrupted mitochondrial dynamics (i.e., fusion/fission balance), which are essential for normal mitochondria structure and function, are documented in AD. Caveolin-1 (Cav-1), a membrane/lipid raft (MLR) scaffolding protein regulates metabolic pathways in several different cell types such as hepatocytes and cancer cells. Previously, we have shown decreased expression of Cav-1 in the hippocampus of 9-month (m) old PSAPP mice, while hippocampal overexpression of neuron-targeted Cav-1 using the synapsin promoter (i.e., SynCav1) preserved cognitive function, neuronal morphology, and synaptic ultrastructure in 9 and 12 m PSAPP mice. Considering the central role of energy production in maintaining normal neuronal and synaptic function and survival, the present study reveals that PSAPP mice exhibit disrupted mitochondrial distribution, morphometry, and respiration. In contrast, SynCav1 mitigates mitochondrial damage and loss and enhances mitochondrial respiration. Furthermore, by examining mitochondrial dynamics, we found that PSAPP mice showed a significant increase in the phosphorylation of mitochondrial dynamin-related GTPase protein (DRP1), resulting in excessive mitochondria fragmentation and dysfunction. In contrast, hippocampal delivery of SynCav1 significantly decreased p-DRP1 and augmented the level of the mitochondrial fusion protein, mitofusin1 (Mfn1) in PSAPP mice, a molecular event, which may mechanistically explain for the preserved balance of mitochondria fission/fusion and metabolic resilience in 12 m PSAPP-SynCav1 mice. Our data demonstrate the critical role for Cav-1 in maintaining normal mitochondrial morphology and function through affecting mitochondrial dynamics and explain a molecular and cellular mechanism underlying the previously reported neuroprotective and cognitive preservation induced by SynCav1 in PSAPP mouse model of AD.
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Videbæk, Charlotte, Peter Ott, Olaf B. Paulson, and Gitte M. Knudsen. "Blood—Brain Barrier Transport and Protein Binding of Flumazenil and Iomazenil in the Rat: Implications for Neuroreceptor Studies." Journal of Cerebral Blood Flow & Metabolism 19, no. 9 (1999): 948–55. http://dx.doi.org/10.1097/00004647-199909000-00002.

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The calculated fraction of receptor ligands available for blood–brain barrier passage in vivo (favail) may differ from in vitro (feq) measurements. This study evaluates the protein–ligand interaction for iomazenil and flumazenil in rats by comparing feq and favail. Repeated measurements of blood–brain barrier permeability for two benzodiazepine antagonists were performed in 44 rats by the double-indicator technique. Cerebral blood flow was measured by intracarotid Xe-injection. The apparent permeability–surface product (PSapp) was measured while CBF or bolus composition was changed. Comparison of PSapp obtained in the absence and presence of 5% albumin in the injectate yielded favail, whereas feq was measured by equilibrium dialysis. Iomazenil and flumazenil favail was 62% and 82%, respectively, whereas feq was significantly lower, 42% and 61%. The PSapp for iomazenil and flumazenil increased significantly by 89% and 161% after relative CBF increases of 259% and 201%, respectively. The results demonstrate that application of feq in neuroreceptor studies underestimates the plasma input function to the brain. Model simulations render possible that the differences between favail and feq as well as the effect of CBF on PSapp can be caused by capillary heterogeneity.
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Mori, Takashi, Naoki Koyama, Tatsuya Segawa та ін. "Methylene Blue Modulates β-Secretase, Reverses Cerebral Amyloidosis, and Improves Cognition in Transgenic Mice". Journal of Biological Chemistry 289, № 44 (2014): 30303–17. http://dx.doi.org/10.1074/jbc.m114.568212.

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Amyloid precursor protein (APP) proteolysis is required for production of amyloid-β (Aβ) peptides that comprise β-amyloid plaques in the brains of patients with Alzheimer disease (AD). Here, we tested whether the experimental agent methylene blue (MB), used for treatment of methemoglobinemia, might improve AD-like pathology and behavioral deficits. We orally administered MB to the aged transgenic PSAPP mouse model of cerebral amyloidosis and evaluated cognitive function and cerebral amyloid pathology. Beginning at 15 months of age, animals were gavaged with MB (3 mg/kg) or vehicle once daily for 3 months. MB treatment significantly prevented transgene-associated behavioral impairment, including hyperactivity, decreased object recognition, and defective spatial working and reference memory, but it did not alter nontransgenic mouse behavior. Moreover, brain parenchymal and cerebral vascular β-amyloid deposits as well as levels of various Aβ species, including oligomers, were mitigated in MB-treated PSAPP mice. These effects occurred with inhibition of amyloidogenic APP proteolysis. Specifically, β-carboxyl-terminal APP fragment and β-site APP cleaving enzyme 1 protein expression and activity were attenuated. Additionally, treatment of Chinese hamster ovary cells overexpressing human wild-type APP with MB significantly decreased Aβ production and amyloidogenic APP proteolysis. These results underscore the potential for oral MB treatment against AD-related cerebral amyloidosis by modulating the amyloidogenic pathway.
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Holcomb, Leigh A., Muralikrishnan Dhanasekaran, Angie R. Hitt, Keith A. Young, Mark Riggs, and Bala V. Manyam. "Bacopa monniera extract reduces amyloid levels in PSAPP mice." Journal of Alzheimer's Disease 9, no. 3 (2006): 243–51. http://dx.doi.org/10.3233/jad-2006-9303.

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Dissertations / Theses on the topic "Psappha"

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Aluotto, Sergio Francisco Braga. "Possibilidades interpretativas em Psappha de Iannis Xenakis." Universidade Federal de Minas Gerais, 2011. http://hdl.handle.net/1843/AAGS-96GJHD.

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The main goal of this paper is to survey the interpretive possibilities for Psappha by Iannis Xenakis, a multiple percussion solo piece whose graphic score, along with the instructions on the Explanatory Note, provides several openings for the participation of the performer. Given the historical importance of the work and compositional innovations by Xenakis, this important solo has been widely presented since its composition, resulting in very distinct performances. However, after searching for related studies and analyzing performances, it was observed that some of the interpretive possibilities inherent to the score have been little explored. In order to speculate on such possibilities, this study sought, through a musical analysis combined with performance practices, to propose instrumentation and techniques that could enable the interpretation of the different meanings attributed to the accents in Psappha, poorly explored until now. As a result of this study, I will present considerations concerning the various nalyses of the work and performance records studied. Moreover, I will share further notes, possibilities and technical solutions devised from personal interpretive studies.<br>O objetivo central desta dissertação é fazer um levantamento de possibilidades interpretativas em Psappha, de Iannis Xenakis, obra escrita para percussão múltipla solo cuja partitura gráfica, juntamente com as instruções apresentadas na nota explicativa, fornece diversas aberturas para a participação do intérprete. Devido à importância histórica da obra e às inovações composicionais de Xenakis, desde sua estreia este importante solo tem sido amplamente apresentado, demonstrando em suas performances resultados bastante distintos. Entretanto, após pesquisa de inúmeros trabalhos relacionados e análise de diversas performances, observou-se que algumas possibilidades interpretativas inerentes à partitura ainda foram pouco exploradas. Com objetivo de especular sobre tais liberdades, esta pesquisa buscou, através de uma análise musical aliada a estudos de performance, propor instrumentações e técnicas de execução que viabilizassem sobretudo a interpretação dos diferentes significados atribuídos às notas acentuadas em Psappha, até hoje pouco explorados. Como resultado desta pesquisa, apresento considerações relativas às diversas análises da obra e aos registros de performance estudados. Além disso, compartilho alguns apontamentos, possibilidades e soluções técnicas alcançadas em estudos interpretativos pessoais.
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Smith, Alyssa Gretchen. "An examination of notation in selected repertoire for multiple percussion." Connect to this title online, 2005. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1118639448.

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Thesis (D.M.A.)--Ohio State University, 2005.<br>Title from first page of PDF file. Document formatted into pages; contains xiv, 107 p.; also includes graphics, music. Includes bibliographical references (p. 103-107). Available online via OhioLINK's ETD Center.
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Weng, Yen-Ching, and 翁嬿景. "The Analysis and Interpretation of 《Psappha》Percussion Solo by Iannis Xenakis." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/r3z265.

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Mechels, Malte [Verfasser]. "Beschreibung der psychosozialen Versorgung onkologisch erkrankter Kinder und ihrer Familien in Deutschland : eine vertiefte Auswertung der Studie der PSAPOH zur psychosozialen Versorgung 2002 / vorgelegt von: Malte Mechels." 2009. http://d-nb.info/100092985X/34.

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Books on the topic "Psappha"

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Psappha: A Novel of Sappho. Upstart Press, 2000.

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