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Journal articles on the topic 'Pseudarthrosis, therapy'

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1

Mouad. Yazidi, Abdelhakim. Kabil, Rime. Dades, et al. "Pseudarthrosis of the scaphoid: what place for conservative treatment using extracorporeal shock wave therapy?" World Journal of Advanced Research and Reviews 26, no. 2 (2025): 038–42. https://doi.org/10.30574/wjarr.2025.26.2.1540.

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Pseudarthrosis of the scaphoid is a relatively frequent complication (5-10%), the pathophysiology of which is linked in particular to poor vascularization, especially of the proximal pole. The optimal treatment for pseudarthrosis of the scaphoid has not yet been established and remains controversial. Among the non-surgical options, extracorporeal shock wave therapy (ESWT) has proved to be a reliable and effective non-invasive modality for patients with delayed or non-healing fractures. We report a retrospective study conducted in the Department of Physical and Rehabilitation Medicine at CHU Ib
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2

Almustafa, Salman. "Extracorporeal Shockwave Therapy for Acromion Pseudarthrosis." Journal of King Abdulaziz University - Medical Sciences 26, no. 1 (2019): 59–63. http://dx.doi.org/10.4197/med.26-1.8.

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Fracture of acromion is uncommon because of its unique anatomical structure and location. Usually it heals by itself using conservative therapy intervention, and a subject’s shoulder can get back to its functional performance without surgical approach. However, rare cases may not recover due to pseudarthrosis taking place, surgical avoidance plus using noninvasive tools to manage acromion pseudarthrosis with the application of extracorporeal shockwave therapy at medium to high intensity is the author's motivation to report this condition. Likewise, to our knowledge, there is no published liter
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3

Mariaud-Schmidt, Rocío P., Sergio Rosales-Quintana, Emilio Bitar, et al. "Hamartoma Involving the Pseudarthrosis Site in Patients with Neurofibromatosis Type 1." Pediatric and Developmental Pathology 8, no. 2 (2005): 190–96. http://dx.doi.org/10.1007/s10024-004-1004-1.

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Congenital pseudarthrosis is a rare disease with variable clinical effects. The disease remains 1 of the most controversial pediatric entities in terms of etiopathogenesis, therapy, and prognosis. Between 0.5% and 2.2% of patients with neurofibromatosis demonstrate pseudarthrosis in any of the long bones. The exact origin of the lesion is even unclear; although several attempts have been made to determine the type of tissue involving the pseudarthrosis site, only fibrous tissue has been documented in different reports. We present 2 unrelated Mexican patients (male and female) with familial neu
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4

Stojanovic, Gordan. "Hyperbaric Oxygenation in Treatment of Femoral Pseudoarthrosis Caused by Osteomyelitis." Experimental and Applied Biomedical Research (EABR) 24, no. 1 (2023): 79–83. http://dx.doi.org/10.2478/sjecr-2020-0009.

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Abstract Post-traumatic osteomyelitis is a common complication of open fractures. Most infections can be resolved by aggressive wound debridement, antibiotics, and normal wound drainage. However, the eradication of infection can be challenging in patients with chronic infection. The pseudarthrosis caused in this way is maintained and difficult to treat even when the infection is cured. Persistent infection may sometimes require suppressive therapy or even limb amputation to control the disease. Improvements in medical treatment have led to increased survivorship and reduced disability in these
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5

Zelyanin, A. S., A. A. Sokov, M. Yu Khanin, et al. "Reconstruction of the clavicle in the pseudarthrosis after radiation therapy." Военно-медицинский журнал 343, no. 4 (2022): 27–32. http://dx.doi.org/10.52424/00269050_2022_343_4_27.

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6

Müller, E. J., M. Wick, O. Russe, and G. Muhr. "Traumatic pseudarthrosis of the dens axis. Aetiology, course and therapy." Der Unfallchirurg 101, no. 10 (1998): 750–54. http://dx.doi.org/10.1007/s001130050333.

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7

Müller, E. J., M. Wick, O. Russe, and G. Muhr. "Traumatic pseudarthrosis of the dens axis. Aetiology, course and therapy." Journal of Orthopaedic Trauma 13, no. 1 (1999): 71. http://dx.doi.org/10.1097/00005131-199901000-00025.

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8

Safaee, Michael M., Cecilia L. Dalle Ore, Corinna C. Zygourakis, Vedat Deviren, and Christopher P. Ames. "Estimating a price point for cost-benefit of bone morphogenetic protein in pseudarthrosis prevention for adult spinal deformity surgery." Journal of Neurosurgery: Spine 30, no. 6 (2019): 814–21. http://dx.doi.org/10.3171/2018.12.spine18613.

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OBJECTIVEBone morphogenetic protein (BMP) is associated with reduced rates of pseudarthrosis and has the potential to decrease the need for revision surgery. There are limited data evaluating the cost-benefit of BMP for pseudarthrosis-related prevention surgery in adult spinal deformity.METHODSThe authors performed a single-center retrospective review of 200 consecutive patients with adult spinal deformity. Demographic data and costs of BMP, primary surgery, and revision surgery for pseudarthrosis were collected. Patients with less than 12 months of follow-up or with infection, tumor, or neuro
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9

Mithofer, K. "Pseudarthrosis of the first rib in the overhead athlete." British Journal of Sports Medicine 38, no. 2 (2004): 221–22. http://dx.doi.org/10.1136/bjsm.2002.002998.

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10

Siegel, Geoffrey, Nilesh Patel, and Rakesh Ramakrishnan. "Rectocutaneous fistula and nonunion after TranS1 axial lumbar interbody fusion L5–S1 fixation." Journal of Neurosurgery: Spine 19, no. 2 (2013): 197–200. http://dx.doi.org/10.3171/2013.5.spine11523.

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The authors report a case of rectal injury, rectocutaneous fistula, and pseudarthrosis after a TranS1 axial lumbar interbody fusion (AxiaLIF) L5–S1 fixation. The TranS1 AxiaLIF procedure is a percutaneous minimally invasive approach to transsacral fusion of the L4–S1 vertebral levels. It is gaining popularity due to the ease of access to the sacrum through the presacral space, which is relatively free from intraabdominal and neurovascular structures. This 35-year-old man had undergone the procedure for the treatment of degenerative disc disease. The patient subsequently presented with fever, s
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11

Vukasinovic, Zoran, Dusko Spasovski, Igor Seslija, Ismet Gavrankapetanovic, Elvir Bazdar, and Zorica Zivkovic. "Congenital pseudarthrosis of lower leg treated by almost outdated method: Case report." Srpski arhiv za celokupno lekarstvo 142, no. 1-2 (2014): 89–93. http://dx.doi.org/10.2298/sarh1402089v.

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Introduction. Congenital pseudarthrosis of tibia is a rare congenital deformity with progressive evolution. Treatment is vague and difficult, and many methods have been used - from once mandatory early amputation to contemporary operative (Ilizarov method, free microvascular fibular graft) and adjuvant methods (electrostimulation, biphosphonates, bone morphogenetic protein). We present the usage of once popular method of homologous graft insertion and intramedullary fixation. Case Outline. This is a case report of male patient with pseudarthrosis involving both crural bones (Boyd type 5), diag
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12

Rizvanov, A., R. Salikhov, O. Teplov, M. Chekunov, and I. Pankov. "Gene-activated demineralized bone allograft in therapy of clavicle pseudarthrosis (Clinical case)." Медицинский вестник МВД 116, no. 1 (2022): 17–21. http://dx.doi.org/10.52341/20738080_2022_116_1_17.

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13

Anthonissen, Joris, Christian Ossendorf, Thomas Vetter, Björn Habermann, and Pol M. Rommens. "Bilateral Pseudarthrosis of the Femoral Neck in a 25-Year-Old Male with Hereditary Hypophosphatemic Rickets." Case Reports in Orthopedics 2014 (2014): 1–3. http://dx.doi.org/10.1155/2014/312712.

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Hereditary hypophosphatemic rickets (HHR) is a rare disorder of renal phosphate wasting and the most common form of heritable rickets. Here, we report a case of an active 25-year-old male with HHR showing atraumatic bilateral femoral neck pseudarthrosis after 4 years of consecutive knee pain. A conservative therapy was administered, taking into account both the risks of surgical treatment and the little impairment even in the sport activities which the patient experienced.
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14

Naested, J., U. Jørgensen, and C. Tørholm. "Pseudarthrosis of the acromion - a differential diagnosis in anterolateral shoulder pain." Scandinavian Journal of Medicine & Science in Sports 5, no. 2 (2007): 105–6. http://dx.doi.org/10.1111/j.1600-0838.1995.tb00021.x.

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15

Bielak, Maciej, Ryszard Bielak, Kamila Kędra, et al. "Congenital Pseudarthrosis of the Clavicle Joint and its impact on sports participation – Description of 2 Cases: diagnosis and treatment." Journal of Education, Health and Sport 21, no. 1 (2023): 123–34. http://dx.doi.org/10.12775/jehs.2023.21.01.013.

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Congenital Pseudarthrosis of the Clavicle (CPC) is a rare condition stemming fromincomplete clavicular ossification nuclei fusion. Our work discusses CPC’s history, etiology,clinical features, and methods of therapy. We especially emphasize athletes affected by this condition. Here we presents two clinical cases, treatmentapproaches and outcomes. CPC’s distinct presentation, often painless, with central claviculardiscontinuity and swelling, allows to differentiate it from other conditions. However, in sport athletes, due to the significant physical exertion involved, symptoms can manifest. Acc
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16

Bose, Bikash. "Fracture of S1–S2 after L4—S1 decompression and fusion." Journal of Neurosurgery: Spine 99, no. 3 (2003): 310–12. http://dx.doi.org/10.3171/spi.2003.99.3.0310.

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✓ The author describes a woman in whom an S1–2 fracture developed after L4—S1 decompression and fusion. Osteoporosis was not present, but the lesion failed to respond to conservative therapy, necessitating surgical extension of the spinal fusion. Although biomechanical complications of lumbosacral fusion are uncommon, pseudarthrosis, degenerative spondylolisthesis, and stress fractures have been reported. To date, only four cases of sacral stress fracture appear in the literature, all involving female patients and reportedly associated with osteoporosis. Unlike the present case, the fracture r
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17

Hertsen, H. I., Yu K. Remeniuk, H. H. Bilonozhkin, and M. V. Sikorska. "Rationale for the Use of Extracorporeal Shock Wave Therapy in the Treatment of Delayed Union of Bone Fractures and Pseudoarthrosis." Visnyk Ortopedii Travmatologii Protezuvannia, no. 2(113) (August 31, 2022): 48–57. http://dx.doi.org/10.37647/0132-2486-2022-113-2-48-57.

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Relevance. Violation of bone formation processes continues to occupy a relatively high level, reaching 2.7-27.1%, so the search for new methods for their treatment and prevention remains relevant. One of these methods is extracorporeal shock wave therapy. Views on the influence of the extracorporeal shock wave therapy on the processes of bone formation significantly differ.
 Objective: to study the effect and mechanism of action of shock wave therapy on the processes of reparative osteogenesis in an experiment and the effect of the method on delayed union of bone fractures and pseudarthro
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18

Masgutov, Ruslan, Mikhail Chekunov, Margarita Zhuravleva, et al. "Use of Gene-Activated Demineralized Bone Allograft in the Therapy of Ulnar Pseudarthrosis. Case Report." BioNanoScience 7, no. 1 (2016): 194–98. http://dx.doi.org/10.1007/s12668-016-0325-7.

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19

OʼNeal, Michael, Timothy M. Ganey, and John A. Ogden. "First Rib Stress Fracture and Pseudarthrosis in the Adolescent Athlete: The Role of Costosternal Anatomy." Clinical Journal of Sport Medicine 19, no. 1 (2009): 65–67. http://dx.doi.org/10.1097/jsm.0b013e3181919495.

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20

Skryabin, E. G., D. A. Romanenko, Yu V. Evstropova, and A. S. Nazarova. "Review of current pain management in patients with lumbosacral transitional vertebrae." Pacific Medical Journal, no. 2 (June 13, 2023): 9–14. http://dx.doi.org/10.34215/1609-1175-2023-2-9-14.

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Pain in patients with transitional lumbosacral vertebrae is managed with surgical and non-surgical treatment. The non-surgical treatment involves techniques of traditional oriental medicine, manual therapy, physiotherapeutic procedures, and pharmacological blockade. Surgical interventions include resection of the pseudarthrosis, minimally invasive endoscopic surgery, radiofrequency ablation, and interbody fusion. The paper presents immediate and, in some cases, long-term outcomes, the causes of unsatisfactory outcomes and complications. The relevance of the study stems from the high prevalence
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21

Smolle, Christian, Judith C. J. Holzer-Geissler, Patrick Mandal, et al. "The Vascularized Fibula as Salvage Procedure in Extremity Reconstruction: A Retrospective Analysis of Time to Heal and Possible Confounders." Life 14, no. 3 (2024): 318. http://dx.doi.org/10.3390/life14030318.

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The vascularized fibula transfer is a well-established technique for extremity reconstruction, but operative planning and patient selection remains crucial. Although recently developed techniques for bone reconstruction, such as bone segment transfer, are becoming increasingly popular, bone defects may still require vascularized bone grafts under certain circumstances. In this study, 41 cases, 28 (68%) men and 13 (32%) women (median age: 40 years), were retrospectively analyzed. Therapy-specific data (flap vascularity [free vs. pedicled] size in cm and configuration [single- vs. double-barrel]
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22

Longo, Umile Giuseppe, Ugo Trovato, Mattia Loppini, et al. "Tissue Engineered Strategies for Pseudoarthrosis." Open Orthopaedics Journal 6, no. 1 (2012): 564–70. http://dx.doi.org/10.2174/1874325001206010564.

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Numerous classification systems of non-union have been proposed based on: presence or absence of infection, radiographic features, clinical findings, biologic activity, location and shape. The management of pseudarthrosis is strongly related to the type of non-union (infected versus uninfected, atrophic versus hypertrophic). Surgical management of pseudarthrosis is generally effective with a success rate ranging from 75 to 100%. Nevertheless, in a relatively high number of instances several combined treatments are required for the fracture healing. The current gold standard to stimulate the bo
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23

Carmen C., Esquivia, Pira Jo, Esquivia Pajaro Carmen, and Pira Paredes Jose. "No. 163 Management Response in Post-Traumatic Pseudarthrosis Scaphoid With Extracorporeal Shock Wave Therapy. A Case Report." PM&R 6, no. 8 (2014): S127. http://dx.doi.org/10.1016/j.pmrj.2014.08.162.

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24

Wild, Claudia, Mahmoud Khene, and Stefan Wanke. "EXTRACORPOREAL SHOCK WAVE THERAPY IN ORTHOPEDICS." International Journal of Technology Assessment in Health Care 16, no. 1 (2000): 199–209. http://dx.doi.org/10.1017/s0266462300161173.

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Objective: Extracorporeal shock wave therapy (ESWT) as an emerging technology in orthopedics has been assessed in Austria with the objective to establish a scientific basis for pending and pressing health policy decisions. Despite encouraging results within some indications and the promising prospect of a noninvasive treatment for some orthopedic diseases, it seemed crucial to assess this new field of application in the light of evidence-based standards, without forgetting the reality of healthcare decisions. This article presents the results of the abovementioned assessment in the context of
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Beck, Sascha, André Busch, Christoph Zilkens, Sebastian Warwas, and Marcus Jäger. "Partial Hemiresurfacing of Osteochondral Defects of the Talus? Surgical Technique and Preliminary Report from Four Patients." Zeitschrift für Orthopädie und Unfallchirurgie 156, no. 04 (2018): 414–22. http://dx.doi.org/10.1055/s-0044-100731.

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Abstract Background: Osteochondral lesions of the medial talus (OLT) frequently lead to chronic ankle pain and osteoarthritis. Arthroscopic debridement, subchondral bone stimulation by drilling, and microfracturing are options for primary therapy in small lesions. In larger lesions, restoration of the talar dome contour seems to be a mandatory course of action. Methods: In a case series, we followed up four patients being treated with a focal resurfacing prosthetic due to large osteochondral talar lesions. In contrast to other studies, we can report on an off-label application to restore defec
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Grecco, Marco Aurélio Sertório, Idyllio do Prado Junior, Murilo Antonio Rocha, and José Wagner de Barros. "Epidemiology of tibial shaft fractures." Acta Ortopédica Brasileira 10, no. 4 (2002): 10–17. http://dx.doi.org/10.1590/s1413-78522002000400002.

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In this work an epidemiological analysis on tibial shaft fractures was performed. During four years, our service treated 179 fractures, 132 in male, 47 in female, aged 14 to 83 years. The 21 to 30-year-old patiens were the more injured. Of these, 120 were open and 59 close fractures of which prevailing cause was road traffic accident. The study based on patients promptuaries analyses and radiographs. The fractures occurred 97 times in the middle third (54.18%); 102 times (56.98%) presented simple fragments, and 57 (31.38%) oblique lines. We treated close and open fractures, respectively, 48 an
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27

Tai, Don Bambino Geno, Robin Patel, Francis Lovecchio, Thomas Kwee, and Marjan Wouthuyzen-Bakker. "State-of-the-Art Review: Diagnosis and Management of Spinal Implant Infections." Clinical Infectious Diseases 79, no. 6 (2024): e65-e71. https://doi.org/10.1093/cid/ciae436.

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Abstract Spinal implant infections are a serious complications of instrumented spinal fusion surgeries, carrying high morbidity and complex management challenges. Early postoperative infections may manifest with wound-healing issues, back pain, and fevers. Magnetic resonance imaging (MRI) is the preferred imaging modality, but can be limited by metal artifacts. For cases with stable implants, surgical debridement with implant retention combined with at least 12 weeks of antibiotics is currently considered appropriate treatment. Staphylococcal infections are ideally treated with biofilm-active
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28

Brusovanik, Georgiy V., Gaetano J. Scuderi, Ronald F. Demeo, and Alexander R. Vaccaro. "Symptomatic Pseudarthrosis After a Traumatically Disrupted Congenital Lumbar Transverse Process-Ileum Fusion (Richard Disease) Treated Successfully With Steroid Injections: A Case Report." PM&R 1, no. 3 (2009): 281–83. http://dx.doi.org/10.1016/j.pmrj.2008.10.011.

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29

Iamaguchi, Raquel Bernardelli, Marco Aurélio de Moraes, Gustavo Bersani Silva, et al. "IS OBESITY A RISK FACTOR FOR FREE VASCULARIZED FIBULAR FLAP COMPLICATIONS?" Acta Ortopédica Brasileira 27, no. 4 (2019): 192–96. http://dx.doi.org/10.1590/1413-785220192704217444.

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ABSTRACT Objective: Although our knowledge of bone reconstruction through microsurgery has increased, the vascularized fibula flap remains one of the most difficult free flap reconstructions to perform, and complications remain a challenge. The incidence of obesity is increasing and is associated with higher rates of free flap complications, which can lead to disastrous results. Since there is no consensus in literature regarding the influence of obesity on free flap outcomes in orthopedic surgeries that require segmental bone reconstruction, the objective of this study was to determine whethe
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30

McLaughlin, Eamon J., Gregory G. Heuer, Robert G. Whitmore, et al. "Treatment of a malignant peripheral nerve sheath tumor and its complications through a multidisciplinary approach." Journal of Neurosurgery: Pediatrics 7, no. 5 (2011): 543–48. http://dx.doi.org/10.3171/2011.2.peds1175.

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The authors report the case of a 14-year-old girl with a residual malignant peripheral nerve sheath tumor after thoracotomy, chemotherapy, and radiation therapy. The residual tumor, which involved the intercostal muscles, aorta, and neural foramina of T4–10, was completely resected through a costotransversectomy and multiple hemilaminotomies with the patient in the prone position and was stabilized using a T1–12 pedicle screw fusion. Postoperatively, the patient developed several infections requiring multiple washouts and prolonged antibiotics. Thirty months after surgery, she developed a bron
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31

Mustafin, R. N. "Skeletal anomalies in patients with neurofibromatosis type 1." Genij Ortopedii 28, no. 2 (2022): 296–304. http://dx.doi.org/10.18019/1028-4427-2022-28-2-296-304.

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Introduction Neurofibromatosis type 1 (NF1) is one of the most common hereditary tumor syndromes. The average incidence of NF1 in the world is 1:3000 of the population. The characteristic signs of the disease are neurofibromas and café-au-lait macules on the skin. 60 % of patients with NF1 develop specific skeletal anomalies: scoliosis, chest deformity, pseudarthrosis, requiring surgical treatment and long-term rehabilitation. It is necessary to develop prognostic criteria for the development of severe skeletal anomalies in NF1 and take early measures to prevent their progression. Congenital p
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32

Jabri, Hatim, Mohammed Tazi Charki, Hicham Abdellaoui, Karima Atarraf, and Moulay Abderrahmane Afifi. "Non-traumatic pathology of the clavicle in children." Pediatric Traumatology, Orthopaedics and Reconstructive Surgery 11, no. 3 (2023): 353–60. http://dx.doi.org/10.17816/ptors397487.

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BACKGROUND: The clavicle in children is a site of multiple types of injuries, post traumatic pathology being predominant, and generally presents no diagnosis problems; in contrast non-traumatic lesions of the clavicle are rare and may pose a diagnostic and therapeutic problems for the orthopaedic surgeon.
 AIM: The objective is to show that the clavicle in children can be a site of infectious, congenital and tumor lesions involving the functional and vital prognosis of the child.
 MATERIALS AND METHODS: A retrospective study including 9 patients over an 9 year period from January 201
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33

Przybylski, Gregory J., and Ashwini D. Sharan. "Single-stage autogenous bone grafting and internal fixation in the surgical management of pyogenic discitis and vertebral osteomyelitis." Journal of Neurosurgery: Spine 94, no. 1 (2001): 1–7. http://dx.doi.org/10.3171/spi.2001.94.1.0001.

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Object. Patients with deep wound infections complicating previously placed internal instrumentation have been successfully treated by debridement and prolonged postoperative antibiotic therapy, which avoided removal of the hardware. Comparatively fewer patients with pyogenic discitis and vertebral osteomyelitis (PDVO) have undergone single-stage debridement, arthrodesis, and internal fixation. The purpose of this study was to determine the efficacy of combining debridement, arthrodesis in which iliac autograft is used, and segmental internal fixation in a single-stage procedure for patients in
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34

Deutsch, Harel, and Michael J. Musacchio. "Minimally invasive transforaminal lumbar interbody fusion with unilateral pedicle screw fixation." Neurosurgical Focus 20, no. 3 (2006): 1–5. http://dx.doi.org/10.3171/foc.2006.20.3.11.

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Object Posterior lumbar interbody fusion (PLIF) has been shown to be effective in the treatment of axial low-back pain. Minimally invasive spine surgery for arthrodesis has several advantages, including quicker patient recovery, less postoperative pain, and less destruction of adjacent tissue. The purpose of this paper is to evaluate the clinical outcomes after PLIF procedures in which unilateral pedicle screw fixation was used. Methods Prospective data were collected in 34 patients undergoing a one-level minimally invasive transforaminal lumbar interbody fusion (TLIF) in 2003. Conservative th
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35

Khorak, K. I., P. G. Kogan, D. G. Parfeev, A. I. Avdeev, A. M. Morozov, and M. E. Piskareva. "The use of bone autoplasty for false joints of the humerus diaphysis." Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH) 14, no. 1 (2024): 68–76. http://dx.doi.org/10.20340/vmi-rvz.2024.1.clin.5.

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Relevance. Fractures of the diaphysis of the humerus account for 1–5% of the total number of traumatic skeletal injuries and 20% of the number of humerus injuries. At the same time, in modern society there is no tendency to reduce traumatism, therefore, the number of surgical interventions aimed at restoring the integrity of the bone does not decrease. Over the decades, approaches to tactics and choice of drugs for correction of defects for fusion and restoration of motor function of the limb have been changing. Physicians from different countries have tried to use both auto- and allografts, w
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FANG, Xiu-tong, and Kirkham B. Wood. "Management of postoperative instrumented spinal wound infection." Chinese Medical Journal 126, no. 20 (2013): 3817–21. http://dx.doi.org/10.3760/cma.j.issn.0366-6999.20131441.

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Background Wound infection following spinal instrumented surgery is a frequent complication. The optimal treatment of acute deep wound infection following spinal instrumentation fusion remains controversial because of variability in cohort identification, definition of an infection, and the instrument used to measure outcomes. This retrospective study evaluated the clinical curative effect for postoperative spinal infection after instrumented spine fusion with extensive debridement, or implant removal. Methods From January 2004 to October 2009, 851 patients were identified who underwent surgic
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Lentini, Audrey, Joseph Djoko, Dan Putineanu, et al. "SEPTIC ORTHO-PLASTIC RECONSTRUCTION SURGERY: OUTCOMES FROM A SIX-YEAR COLLABORATIVE STUDY." Orthopaedic Proceedings 106-B, SUPP_19 (2024): 86. http://dx.doi.org/10.1302/1358-992x.2024.19.086.

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AimBone infections often manifest with soft tissue complications such as severe scarring, fistulas, or ulcerations. Ideally, their management involves thorough debridement of infected bone and associated soft tissues, along with achieving stable bone structure, substantial tissue coverage, and long-term antibiotic therapy. The formation of a multidisciplinary team comprising orthopedic surgeons, plastic surgeons, and infectious disease specialists is essential in addressing the most complex cases.MethodWe conducted a retrospective study during six years (2018-2023) at our university center. Fo
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Frodl, Andreas, Benjamin Erdle, and Hagen Schmal. "Osteosynthesis or non-operative treatment of the fibula for distal lower-leg fractures with tibial nailing: a systematic review and meta-analysis." EFORT Open Reviews 6, no. 9 (2021): 816–22. http://dx.doi.org/10.1302/2058-5241.6.210003.

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Fibular fixation to treat distal lower-leg fractures is a controversial intervention. To ensure better stability itself, better rotational stability, and to prevent secondary valgus dislocation – all these are justifications for addressing the fibula via osteosynthesis. High surgical costs followed by increased risks are compelling reasons against it. The purpose of this study was to systematically review the literature for rates of malunion and malrotation, as well as infections and nonunions. We conducted a systematic review searching the Cochrane, PubMed, and Ovid databases. Inclusion crite
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39

Haid, Regis W., Brian R. Subach, Mark R. McLaughlin, Gerald E. Rodts, and John B. Wahlig. "C1–C2 Transarticular Screw Fixation for Atlantoaxial Instability: A 6-year Experience." Neurosurgery 49, no. 1 (2001): 65–70. http://dx.doi.org/10.1097/00006123-200107000-00010.

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Abstract OBJECTIVE We review a 6-year, single-center experience using the technique of C1–C2 transarticular screw fixation for atlantoaxial instability in 75 consecutive operations. METHODS The study group was composed of 43 men and 32 women, with a mean age of 44 years (range, 8–76 yr). Each patient had documented atlantoaxial instability. In 28 patients (37%), atlantoaxial instability was a result of trauma; in 22 patients, (29%), it was a result of rheumatoid arthritis; in 16 patients (21%), it was a result of prior surgery; and in 9 patients (12%), it was a result of congenital abnormaliti
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DiGiorgio, Anthony M., Rachel Stein, Kevin D. Morrow, Jared M. Robichaux, Clifford L. Crutcher, and Gabriel C. Tender. "The increasing frequency of intravenous drug abuse–associated spinal epidural abscesses: a case series." Neurosurgical Focus 46, no. 1 (2019): E4. http://dx.doi.org/10.3171/2018.10.focus18449.

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OBJECTIVEFew studies have been published specifically examining intravenous drug abuse (IVDA)–associated spinal epidural abscesses (SEAs), an unfortunate sequela of the opioid crisis in the United States. Here, the authors examined a series of patients with IVDA-associated SEAs in order to shed light on this challenging disease entity.METHODSThis study is a retrospective chart review of patients presenting with IVDA-associated SEAs at the authors’ institution from 2013 to 2018, spanning the statewide implementation of opioid-prescribing restrictions.RESULTSA total of 45 patients presented with
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Korovessis, Panagiotis, Vasileios Tsekouras, and Alkis Korovesis. "Fatigue Acetabular Fracture after Lumbopelvic Instrumented Fusion in Elderly." Case Reports in Orthopedics 2021 (September 29, 2021): 1–5. http://dx.doi.org/10.1155/2021/8962203.

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Purpose. Only several cases of acetabular “fatigue”/insufficiency fractures have been reported in elderly patients with osteoporosis. However, fatigue acetabular fracture below lumbopelvic fixation has not been published. This review reports on the frequency and mechanisms of acetabular fatigue fractures in elderly individuals, including postmenopausal osteoporosis, and presents a case of an acetabular “fatigue” fracture in association with lumbopelvic fusion. Methods. We report on a 71-year-old postmenopausal woman who underwent in our department a L2-pelvis instrumented fusion for failed lum
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Skryabin, E. G., A. Yu Krivtsov, O. A. Kicherova, I. N. Klokov, P. B. Zotov, and M. A. Akselrov. "Lumbosacral transitional vertebrae in children and adolescents (literature review, illustrated with clinical observations)." Genij Ortopedii 30, no. 2 (2024): 282–91. http://dx.doi.org/10.18019/1028-4427-2024-30-2-282-291.

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Introduction An analysis of the medical literature devoted to various aspects of transitional lumbosacral vertebrae shows that there are very few publications covering the course of this disease in the pediatric and adolescent population.Aim To study the issues of epidemiology, diagnosis, treatment and prevention of transitional lumbosacral vertebrae in paediatric and adolescent patients based on the analysis of current medical literature and illustrate the material with our own clinical observations.Material and methods To analyze the literature on the topic, 75 papers published between 1984
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Berger, Juliette, Jérome Stirnemann, Céline Bourgne, et al. "The Uptake of Recombinant Glucocerebrosidases by Blood Monocytes From Type 1 Gaucher Disease Patients Is Heterogeneous." Blood 118, no. 21 (2011): 1102. http://dx.doi.org/10.1182/blood.v118.21.1102.1102.

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Abstract Abstract 1102 Introduction: Gaucher disease (GD) is due to an inborn deficiency of glucocerebrosidase (GC), that leads to the accumulation of glucosylceramide in monocytes/macrophages, known as “Gaucher cells”, which are thought to be responsible for a wide range of symptoms. Imiglucerase (CEREZYME®, Genzyme Corporation) (IMI) is the first line treatment of type 1 GD patients. Two new biosimilar agents, velaglucerase-alfa (VPRIV®, Shire Human Genetic Therapies, Dublin, Ireland) (VEL) and taliglucerase-alfa (PROTALIX®, Biotherapeutics, Pfizer) (TAL), have been described as being simila
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Helm, Gregory A., Tord D. Alden, Elisa J. Beres, et al. "Use of bone morphogenetic protein—9 gene therapy to induce spinal arthrodesis in the rodent." Journal of Neurosurgery: Spine 92, no. 2 (2000): 191–96. http://dx.doi.org/10.3171/spi.2000.92.2.0191.

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Object. Bone morphogenetic proteins (BMPs) have been shown to have significant osteoinductive activity in numerous in vitro and in vivo assay systems, and BMP-2 and BMP-7 are currently being evaluated in human clinical studies. In the spinal region, BMPs have been shown to promote spinal arthrodesis at a higher rate than autologous bone alone. The delivery of BMPs via direct or ex vivo gene therapy techniques is also currently being evaluated and has shown promise in several mammalian models. The present study was designed to evaluate the efficacy of the use of direct, percutaneous BMP-9 adeno
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Tarasenko, T., and O. Tarasenko. "AB1407 EFFECTIVENESS OF TREATMENT OF FACET SYNDROME BY THE METHOD OF BLOCKADE OF INTERVERTEBRAL JOINTS UNDER ULTRASOUND CONTROL." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 1933.1–1933. http://dx.doi.org/10.1136/annrheumdis-2023-eular.1761.

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Backgroundrecently there has been an increase in the prevalence of facet syndrome (spondyloarthrosis) in back pain syndromes. This is due to hypodynamia, increased body weight, and the increase in the specific gravity of the so-called “sedentary” professions. With hypertrophy of the intervertebral joints, there is chronic compression of the Lyushka nerve (return nerve), which directly causes pain, as well as constant spasm of the innervating muscles. In the treatment of facet syndromes, many methods are used - drug treatment, massage, various physical methods of influence, etc., but none of th
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Meidinger, Gebhard, S. Hinterwimmer, J. Paul, C. Kirchhoff, and A. B. Imhoff. "V 6 Dürfen Raucher mit einer valgisierenden open-wedge HTO behandelt werden? – Risikofaktoren für die Pseudarthrosen-Entstehung." Sport-Orthopädie - Sport-Traumatologie - Sports Orthopaedics and Traumatology 25, no. 2 (2009): 124. http://dx.doi.org/10.1016/j.orthtr.2009.02.007.

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Dionne, Antoine, Firoz Miyanji, Jennifer A. Dermott, et al. "Canadian Spine SocietyCPSS-01. Abstract ID 48. Is long-term follow-up required for low-grade spondylolisthesis? A prospective study of 247 children followed until skeletal maturityCPSS-02. Abstract ID 101. Major complications following anterior vertebral body tethering surgeryCPSS-03. Abstract ID 164. Late referral of adolescent idiopathic scoliosis: the impact of socioeconomic status and health care utilizationCPSS-04. Abstract ID 97. The impact of curve correction on patient satisfaction — Is straighter better?CPSS-05. Abstract ID 22. Assessing Cobb angle agreement in community spine radiographs: clinical significance in adolescent idiopathic scoliosis patientsCPSS-06. Abstract ID 35. Enhanced Recovery After Surgery does not affect incidence of chronic postsurgical pain and improves postoperative outcomes after pediatric spine surgeryCPSS-07. Abstract ID 102. Predicting overcorrection in anterior vertebral body tethering: Can we improve patient selection?CPSS-08. Abstract ID 66. New artificial intelligence–driven surface topography phone app helps screen patients with spinal deformity: early results from one institutionCPSS-09. Abstract ID 96. Postoperative suicide risk is elevated in patients undergoing posterior spinal instrumentation and fusionCPSS-10. Abstract ID 53. Characterizing antibiotic prophylaxis practices in pediatric deformity spinal surgery and impact on 30-day postoperative infection: an NSQIP pediatric database studyA-11. Abstract ID 16. Preoperative opioid use affects self-reported pain scores in elderly patients undergoing multilevel spinal surgery for adult spinal deformityA-12. Abstract ID 41. The impact of a perioperative Enhanced Recovery After Surgery program on outcomes in adult cervical deformity patientsA-13. Abstract ID 112. A prospective, observational, multicentre study assessing functional improvements after multilevel fusion for adult spinal deformity: 5-year follow-up resultsA-14. Abstract ID 19. Outcomes of preemptive spinal cord stimulation for patients with pain from structural spine deformitiesA-15. Abstract ID 60. T1 pelvic and lumbar pelvic angles normative values: a prospective cohort study of 496 asymptomatic volunteersA-16. Abstract ID 128. How reliable are intraoperative neuromonitoring alerts during non-cord–level spinal deformity surgery? Results from the Spinal Deformity Intraoperative Monitoring studyA-17. Abstract ID 99. Using artificial intelligence to predict postoperative satisfaction for scoliosis patients: a retrospective database studyA-18. Abstract ID 70. A comparison of surgical outcome and equitable access for hip, knee and lumbar spine surgery for end-stage osteoarthritisA-19. Abstract ID 109. What are the predictive factors for compensatory supra-adjacent level lordosis angle changes after lumbar interbody fusion for degenerative spine disease?A-20. Abstract ID 115. Are nonsteroidal anti-inflammatory drugs appropriate for patients recovering from lumbar fusion surgery for elective spine procedures? A systematic review and meta-analysisB-21. Abstract ID 57. The role of bedrest after incidental durotomy in lumbar spineB-22. Abstract ID 44. Decompression versus decompression and fusion and the influence of the lordosis distribution index in the outcome of patients with degenerative lumbar spondylolisthesisB-23. Abstract ID 103. Clinical outcomes after indirect decompression through anterior approaches versus direct decompression with posterior approaches in lumbar interbody fusion — a propensity-matched analysis using data from the Canadian Spine Outcomes and Research NetworkB-24. Abstract ID 141. Candidate epigenetic polygenic risk score to predict pain response following surgical intervention for lumbar spinal stenosis due to spine osteoarthritisB-25. Abstract ID 94. Comparative analysis of characteristics and clinical outcomes of discectomy without fusion between upper and lower lumbar disc herniations: a Canadian Spine Outcomes Research Network (CSORN) studyB-26. Abstract ID 63. Improvement in multifidus muscle quality following a 12-week exercise program in patients with chronic low back pain: a randomized controlled trialB-27. Abstract ID 121. Predictive factors for distal adjacent segment disease in short lumbar fusions ending at L5B-28. Abstract ID 75. Impact of 1- or 2-level minimally invasive surgery versus open lumbar interbody fusion on postoperative opioid useB-29. Abstract ID 127. Revision lumbar fusions exhibit worse clinical outcomes when compared with primary fusions: a matched cohort analysis using the Canadian Spine Outcomes and Research Network RegistryB-30. Abstract ID 74. Outcome prediction following lumbar disc surgery (Opti-Disc): a longitudinal study of outcome trajectories, prognostic factors and risk modelsC-31. Abstract ID 56. Mild degenerative cervical myelopathy — patients at risk of conservative treatment failureC-32. Abstract ID 61. Automated magnetic resonance imaging risk stratification of clinical deterioration in mild cervical myelopathyC-33. Abstract ID 7. The effects of perioperative adverse events on clinical and patient-reported outcomes after surgery for degenerative cervical myelopathy: an observational cohort study from the Canadian Spine Outcomes and Research NetworkC-34. Abstract ID 11. Anterior versus posterior surgery for patients with degenerative cervical myelopathy: an observational study from the Canadian Spine Outcomes and Research NetworkC-35. Abstract ID 20. Long-term (> 24 months) duration of symptoms negatively impacts patient-reported outcomes following anterior cervical discectomy and fusion for cervical radiculopathyC-36. Abstract ID 24. Predictors associated with achieving the minimal clinically important difference in patient-reported outcomes after surgery for degenerative cervical myelopathy: a national multi-centre cohort analysis from the Canadian Spine Outcomes and Research NetworkC-37. Abstract ID 155. A data-driven classification of degenerative cervical myelopathy leads to clinically relevant subgroups with distinct preoperative features and postsurgical outcomes: a CSORN studyC-38. Abstract ID 148. Clinical outcomes of surgical treatment of degenerative cervical myelopathy: a long-term follow up studyC-39. Abstract ID 137. Fulfillment of patient expectations after surgery for degenerative cervical myelopathy. A retrospective analysis of prospectively collected data from the multicentre Canadian Surgical Spine Registry (CSORN)C-40. Abstract ID 28. Re-analysis of the CSM-Protect multicentre randomized controlled trial reveals a global treatment benefit of riluzole in patients undergoing surgery for degenerative cervical myelopathyD-41. Abstract ID 33. The growing problem of spine surgery wait times in British Columbia: longitudinal trends and impacts on perioperative outcomesD-42. Abstract ID 119. Patient expectations and surgical satisfaction in primary versus revision lumbar spine surgeryD-43. Abstract ID 105. Impact of surgical wait time on prescription opioid utilization in patients having surgery for degenerative spinal conditionsD-44. Abstract ID 108. Emergency department “bounce backs” after posterior decompression surgeryD-45. Abstract ID 21. Can patients with cerebrospinal fluid leak be discharged home on the same day after tubular microdiscectomy: retrospective cohort analysisD-46. Abstract ID 42. Efficacy of virtual triage in patients with low back painD-47. Abstract ID 54. Wait times and health resource utilization by patients awaiting spine assessment and surgery in ManitobaD-48. Abstract ID 165. Characteristics of attrition of patients enrolled in the Canadian Spine Outcomes and Research Network registry and prospective studies for degenerative spine surgeryD-49. Abstract ID 67. Waiting for spine surgery in Canada: an evaluation of wait times, wait lists and surgeries performed before and after the onset of the COVID-19 pandemicD-50. Abstract ID 88. Words that lead to the operating room: identifying terminology patterns in referral letters for lower back pain and their association with surgery using Natural Language ProcessingE-51. Abstract ID 38. Quantifying the association between surgical spine approach and tracheostomy timing after traumatic cervical spinal cord injuryE-52. Abstract ID 25. Withdrawal of life-supporting treatment in spinal cord injury: a large multicentre observational cohort studyE-53. Abstract ID 34. Comparative analysis of spinal cord–derived endogenous stem cells and induced pluripotent stem cells for spinal cord injury treatmentE-54. Abstract ID 65. Specialized care is associated with reduced risk for unplanned readmissions following traumatic incomplete spinal cord injuryE-55. Abstract ID 113. The association between mean arterial blood pressure augmentation and intraparenchymal hemorrhage after acute spinal cord injuryE-56. Abstract ID 27. Impact of traumatic cervical spinal cord injury on income and employment status in a Canadian cohortE-57. Abstract ID 37. Circuit interrogation of whole brain reveals a novel neuromodulatory target to improve locomotion after traumatic spinal cord injuryE-58. Abstract ID 118. Prediction of 5-year mortality following spinal cord injury using a frailty index as a measure of deficitsE-59. Abstract ID 125. Health economic analysis of neurologically intact thoracolumbar A3 and A4 fractures is dominant in supporting surgery over nonsurgical treatmentE-60. Abstract ID 49. Safety and feasibility of early activity-based therapy following traumatic spinal cord injury: final results from the PROMPT-SCI trialE-61. Abstract ID 107. Identification of proteins in the blood serum related to neurological recovery after traumatic spinal cord injuryE-62. Abstract ID 18. Critical appraisal of frailty and sarcopenia tools in spinal oncologyE-63. Abstract ID 100. Early neurological recovery following surgical treatment of spinal cord injuries due to spinal tumours. A retrospective cohort study of 113 patientsE-64. Abstract ID 139. Cervical spine chordomas: surgical outcome assessment in a multicentre cohort from the Primary Tumor Research and Outcomes Network (PTRON)E-65. Abstract ID 83. The effect of hemodynamic management and venous thromboembolism prophylaxis on intraparenchymal hemorrhage progression in a porcine model of traumatic spinal cord injuryP-100. Abstract ID 92. Economic comparisons of endoscopic spine surgery: a systematic reviewP-101. Abstract ID 120. Prospective Prophylactic Antibiotics Regimen in Scheduled Spine Surgery — the PPARiSSS Cohort. An independently verified and validated cohort study of extended antibiotic prophylaxis combined with standardized tissue handling and perioperative wound care in 1000 scheduled lumbar pedicle-screw implant surgeriesP-102. Abstract ID 130. The impact of concurrent deformity on patient-reported outcomes following 1- to 3-level lumbar surgery not aimed at deformity correctionP-103. Abstract ID 136. Describing available preoperative education methods and comparing outcomes for spinal fusion candidates: a cross-Canada studyP-104. Abstract ID 144. Matched-cohort investigation comparing minimally invasive and traditional open lumbar decompression and interbody fusion: a Canadian Spine Outcomes and Research Network (CSORN) studyP-105. Abstract ID 146. Measuring differences between interlamellar properties of the annulus fibrosus from degenerative disc disease and nondiseased young donor patientsP-106. Abstract ID 147. Assessing collagen damage in annulus fibrosus from patients with degenerative disc disease using a collagen hybridizing peptideP-107. Abstract ID 150. The effects of using antidepressants for presurgical pain management on postsurgical pain and disability outcomes in patients with lumbar spinal stenosisP-108. Abstract ID 163. Pseudarthrosis of the lumbar spine: a systematic reviewP-109. Abstract ID 8. What is the diagnostic accuracy of community spine x-rays for adolescent idiopathic scoliosis brace candidates?P-110. Abstract ID 14. A comparative study of protocols for spinal casting in severe early-onset scoliosis: a 4-year progression-free survival analysisP-111. Abstract ID 36. Aquatic therapy for chronic low back pain: preliminary insights into muscle strength and psychological outcomesP-112. Abstract ID 51. The true cost of late referral in adolescent idiopathic scoliosis: a 5-year follow-up and cost analysis studyP-113. Abstract ID 52. The effect of transcutaneous electrotherapies on self-reported outcomes in patients with chronic low back pain: a systematic review and meta-analysisP-114. Abstract ID 84. The immediate effect of a single treatment of neuromuscular electrical stimulation with the StimaWELL 120MTRS system on multifidus stiffness in patients with chronic low back painP-115. Abstract ID 23. Contemporary trends in the incidence and timing of spinal metastases: a population-based retrospective cohort studyP-116. Abstract ID 39. Automated psoas muscle segmentation: radiomic features and surgical fitness in spinal metastatic lung cancerP-117. Abstract ID 76. What is the optimal management of patients with metastatic spine disease with intermediate spinal instability neoplastic scores: To operate or not to operate?P-118. Abstract ID 80. Does the number of spinal metastases affect the survival of patients with lung cancer?P-119. Abstract ID 110. Which patients have the best chances of improving their neurological status after pathologic spine fractures presenting with neurologic compromise?P-120. Abstract ID 116. Could patients’ neurological status deteriorate after posterior decompression and fusion for unstable vertebral pathologic fractures?P-122. Abstract ID 50. Challenging decision-making in spinal firearm and stab injuries: case series from a Brazilian trauma centreP-123. Abstract ID 55. Trends and impact of pharmacological venous thromboembolism prophylaxis timing for complete traumatic cervical spinal cord injury across North American trauma centres from 2013 to 2020P-124. Abstract ID 58. Standardizing a magnetic resonance imaging library of acute traumatic spinal cord injury in CanadaP-126. Abstract ID 69. Is the level of consent to a national research registry associated with patient outcomes following traumatic spinal cord injury? A population-based study from the Rick Hansen Spinal Cord Injury Registry (RHSCIR)P-127. Abstract ID 78. Spinal cord injuries secondary to mountain biking accidents — a cause for national alarmP-128. Abstract ID 85. Can the Montreal Acute Classification of Spinal Cord Injury (MAC-SCI) be used to detect early perioperative deteriorations following traumatic spinal cord injury? A validation studyP-129. Abstract ID 87. Building of a national Canadian magnetic resonance imaging repository for deep-learning segmentation of edema and hemorrhageP-132. Abstract ID 134. Functional and patient-reported outcomes following peripheral nerve transfers to improve upper limb function in individuals with cervical spinal cord injuryP-133. Abstract ID 135. Assessing the efficacy of a novel multidisciplinary outpatient program for improving upper limb function in cervical spinal cord injuryP-134. Abstract ID 153. Assessing neural stem progenitor cell proliferation: identifying effective predictorsP-136. Abstract ID 159. Identifying care pathways of patients with traumatic spinal cord injury using novel AI methodsP-137. Abstract ID 160. Ski- and snowboard-related spinal trauma and spinal cord injury: a northeastern level 1 trauma experienceP-138. Abstract ID 161. Robot-assisted needle injection for biomaterial delivery in treating spinal cord injuryP-141. Abstract ID 5. Impact of tobacco on nonunion rate and patient-reported outcomes in spinal fusion surgery: a systematic review and meta-analysisP-142. Abstract ID 6. The economic burden of diabetes in spinal fusion surgery: a systematic review and meta-analysisP-144. Abstract ID 47. Integration of a self-evaluation tool into surgical case logs for tracking spine fellow progressP-145. Abstract ID 64. Ligament damage models in the lumbar spine: modelling using a novel 3D-printable analogue modelP-146. Abstract ID 68. Interactions between mechanical and immune modulation of human mesenchymal stem cells on micronanotextured Ti-6Al-4V surfacesP-147. Abstract ID 72. Implementation of workshops in regional British Columbia to enhance clinician confidence in spinal cord injury care provisionP-148. Abstract ID 77. Altering physician referral practices is challenging, but not impossible: Spine Assessment Clinic quality-improvement studyP-149. Abstract ID 81. Feasibility and outcomes of minimally invasive tubular spinal cord stimulation lead placement: a retrospective case series studyP-150. Abstract ID 90. Thermal optimization of robotic piezoelectric osteotomy motion for the purpose of pedicle screw pilot hole preparationP-151. Abstract ID 98. The need for neuromonitoring during growing rod surgical distractions in early-onset scoliosisP-152. Abstract ID 106. Case report: L1 compression fracture in a patient with multilevel lumbar retrosomatic cleft and pedicular dysplasiaP-153. Abstract ID 111. Development of improved patient educational material for elective spine surgery: a patient-engagement initiativeP-154. Abstract ID 114. The natural history of spinal cord cavernous malformation: a systematic review and meta-analysisP-155. Abstract ID 124. The influence of obesity on spinal nonunion: a systematic review and meta-analysisP-156. Abstract ID 126. Meta-analysis of the effects of diabetes mellitus on fusion rates and patient-related outcomes in spinal fusion surgeryP-158. Abstract ID 91. Cost savings analysis through a direct-to-hospital sales model for interbody cagesP-159. Abstract ID 158. A survey comparing postsurgical opioid prescribing practices of neurosurgeons around the world following lumbar discectomies and craniotomiesP-160. Abstract ID 45. Performance comparison between Hounsfield units and dual-energy x-ray absorptiometry in predicting lumbar interbody cage subsidence after circumferential lumbar fusionP-67. Abstract ID 73. Can classical machine-learning models predict long-term degenerative cervical myelopathy outcomes?P-68. Abstract ID 131. The relative importance of cervical myelopathy treatment outcomes to spine surgeons and family physicians in Canada: a discrete-choice experimentP-69. Abstract ID 133. Effect of elective cervical spine surgery on mental health of patients with degenerative cervical myelopathy: a CSORN studyP-70. Abstract ID 143. Using smartphones for clinical assessment in cervical spondylotic myelopathy: a small cohort studyP-71. Abstract ID 151. Cervicothoracic construct fixation comparison using finiteelement analysisP-72. Abstract ID 152. Posterior cord syndrome: a possible indication for clinical failure in anterior cervical discectomy and fusion for cervical spondylotic myelopathy, and denial of equipoiseP-74. Abstract ID 17. One-third of adult surgical patients with spinal deformity are consuming opioids both pre- and postoperatively, with significant international differences: this is partly a cultural issueP-75. Abstract ID 32. Baseline blood pressure influences frequency of neuro-monitoring alerts during posterior fusion for adolescent idiopathic scoliosisP-77. Abstract ID 59. Effects of teriparatide on complications, surgical outcomes and health-related quality of life in osteoporotic patients undergoing correction of adult spinal deformityP-78. Abstract ID 71. Postoperative day 1 discharge for patients undergoing vertebral body tethering; optimization of a rapid discharge protocolP-79. Abstract ID 79. Characterization of spinopelvic parameters in children under 10 years of age with spondylolisthesis and analysis of progressionP-80. Abstract ID 86. A shifting female-to-male ratio of individuals requiring surgery for adolescent idiopathic scoliosis: a 15-year edit prospective observational studyP-81. Abstract ID 93. Clinical and radiological outcomes of gradual reduction and circumferential fusion of high-grade spondylolisthesis in adolescents. A prospective cohort study of 29 young patientsP-82. Abstract ID 104. Interrater reliability of partially automated segmentation of spinal radiographs in patients with adult spinal deformity using KeOps softwareP-83. Abstract ID 117. Recovery patterns and de novo neurological deficits associated with intraoperative neuromonitoring alerts in cord-level severe spinal deformity surgeries: results from an international multicentre prospective Spinal Deformity Intraoperative Monitoring (SDIM) studyP-84. Abstract ID 122. An evaluation of postsurgical pain management: oral-only morphine versus combined oral and intravenous patient-controlled analgesia in patients with scoliosisP-85. Abstract ID 129. Saving spinal cord function by using intraoperative monitoring and rapid response during spinal deformity surgeryP-87. Abstract ID 145. Structure–function relationships of degenerative and degenerative scoliosis annulus fibrosus — a possible etiological factor in adult deformitiesP-89. Abstract ID 154. The dreaded false negatives: when intraoperative neuromonitoring fails to detect spinal cord and nerve root deficits associated with complex spinal deformity correction — a prospective international study from the AO Spine Knowledge Forum DeformityP-90. Abstract ID 162. What events are associated with intraoperative neuromonitoring alerts in deformity surgeries? Results from the multicentre prospective Spinal Deformity Intraoperative Monitoring (SDIM) studyP-92. Abstract ID 15. Meta-analysis of randomized controlled trials comparing radiation exposure in robot-guided versus freehand spinal fusionP-93. Abstract ID 26. The effects of dynamic pedicle-based stabilization on adjacent segment degeneration: retrospective study at 6-year follow-upP-95. Abstract ID 30. Relationship between paraspinal muscle cross-sectional area, fatty infiltration and muscle strength in patients with chronic low back painP-97. Abstract ID 46. The role of single-photon emission computed tomography with computed tomography in improving pain outcomes following spine interventions: a systematic reviewP-98. Abstract ID 82. Development and validation of a magnetic resonance imaging–based scoring system for lumbar spine assessment: a proposal for convolutional neural network integration for future clinical automationP-99. Abstract ID 89. From text to meaning to surgery: predicting surgical decisions from semantic analysis of referral communications for lower back pain." Canadian Journal of Surgery 67, no. 6suppl1 (2024): S17—S76. http://dx.doi.org/10.1503/cjs.011424.

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Paria, Nandina, Ila Oxendine, David Podeszwa, et al. "Molecular Evidence Supporting MEK Inhibitor Therapy in NF1 Pseudarthrosis." Journal of Bone and Joint Surgery, April 1, 2025. https://doi.org/10.2106/jbjs.24.01007.

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Background: Neurofibromatosis type 1 (NF1) is a genetic condition predisposing children to fracture pseudarthroses. MEK inhibitors are U.S. Food and Drug Administration–approved or are under study for the treatment of malignant pathologies associated with NF1. However, their potential to treat pseudarthrosis is largely unknown. Methods: Primary cells cultured from control bone or fracture pseudarthroses from children with NF1 were treated with vehicle or with the MEK inhibitors trametinib or selumetinib. Gene expression was evaluated with use of transcriptome sequencing (RNAseq), and the activ
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Tatsumura, Masaki, Hisanori Gamada, Shun Okuwaki, et al. "Factors associated with failure of bony union after conservative treatment of acute cases of unilateral lumbar spondylolysis." BMC Musculoskeletal Disorders 22, no. 1 (2021). http://dx.doi.org/10.1186/s12891-020-03940-9.

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Abstract Background If bone union is expected, conservative treatment is generally selected for lumbar spondylolysis. However, sometimes conservative treatments are unsuccessful. We sought to determine the factors associated with failure of bony union in acute unilateral lumbar spondylolysis with bone marrow edema including contralateral pseudarthrosis. Methods This study targeted unilateral lumbar spondylolysis treated conservatively in high school or younger students. Conservative therapy was continued until the bone marrow edema disappeared on MRI and bone union was investigated by CT. We c
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Lansford, Todd, Peter Campbell, Hamid Hassanzadeh, et al. "Pulsed Electromagnetic Fields for Cervical Spine Fusion in Patients with Risk Factors for Pseudarthrosis." Orthopedic Reviews 16 (October 3, 2024). http://dx.doi.org/10.52965/001c.122534.

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Background Certain demographics and/or risk factors contribute to complications following cervical spinal surgery including pseudarthrosis, prolonged pain, and reduced quality of life (QoL). Pulsed electromagnetic field (PEMF) stimulation is a non-invasive therapy that may enhance fusion success in at-risk patients. Objective To evaluate the safety and efficacy of post-operative adjunctive PEMF therapy following cervical spinal surgery in subjects at risk for pseudarthrosis. Methods This prospective, multicenter study investigated PEMF as an adjunctive therapy to cervical spinal fusion procedu
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