Log in

Relevant bibliographies by topics / Pseudo-ternary diffusion / Journal articles

To see the other types of publications on this topic, follow the link: Pseudo-ternary diffusion.

Journal articles on the topic 'Pseudo-ternary diffusion'

Author: Grafiati

Published: 6 September 2023

Last updated: 31 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Pseudo-ternary diffusion.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Aliene, Onyinyechi Gift, and Cyprian Yameso Abasi. "Sorption Kinetics and Diffusion Behaviour of Post-Characterized, Biomodified Waste PET (RIC-1) Bottles Composites." International Journal of Research and Innovation in Applied Science IX, no. XII (2025): 211–23. https://doi.org/10.51584/ijrias.2024.912020.

Full text

Abstract:

This study dwelt on the preparation, characterization, and application of composites made from waste (PET) polyethylene terephthalate bottles with a resin identification code of 1 (RIC-1). These composites were prepared by melt mixing PET matrix with other fillers such as crab shell, clay, and chitin, resulting in binary or ternary composites. The physicochemical properties and characterization of the composites were analyzed using techniques such as , porosity testing, pH point at zero charge, surface area and FTIR. The composites were thereafter applied for the remediation of iron (III) ions

APA, Harvard, Vancouver, ISO, and other styles

2

Leaist, DG. "Concentration Oscillations During Diffusion With Slow First-Order Chemical Reaction in Aqueous Solutions of trans-Dichloro-bis(ethane-1,2-diamine)cobalt(III) Chloride, trans-[Co(en)2Cl2]Cl." Australian Journal of Chemistry 41, no. 4 (1988): 469. http://dx.doi.org/10.1071/ch9880469.

Full text

Abstract:

The rate equations for diffusion and chemical reaction have been solved for isothermal diffusion with the first-order reactionA → Bin stirred diaphragm cells. Provided pseudo-steady-state conditions are established in the diaphragms, the concentration differences across the diaphragm for the reactant and product are predicted to show damped oscillations in time for certain values of the solute diffusivities. Diffusion coefficients have been determined for aqueous solutions of trans-dichlorobis (ethane-1,2-diamine)cobalt(III) chloride in which the 1 : 1 salt slowly converts into a 1:2 salt thro

APA, Harvard, Vancouver, ISO, and other styles

3

Nguyen, Tung Van, Lien Thi Nguyen, Ha Thi Thu Nguyen, and Thu-Huong Le. "Adsorption Studies of Ternary Metal Ions (Cs+, Sr2+, and Co2+) from Water Using Zeolite@Magnetic Nanoparticles (Z@Fe3O4 NPs)." Inorganics 12, no. 11 (2024): 276. http://dx.doi.org/10.3390/inorganics12110276.

Full text

Abstract:

The mixture of three metal ions (Cs+, Sr2+, and Co2+) is commonly found in radioactive waste, which induces several negative health effects. The removal of multiple metal ions is a true challenge for researchers due to the competitive adsorption of ions onto adsorbents. In this study, three metal ions, namely Cs+, Sr2+, and Co2+, have been successfully removed simultaneously from water using zeolite@magnetic nanoparticles (Z@Fe3O4 NPs). The optimized condition for the adsorption of ternary metal ions was obtained at an adsorbent weight of 0.2, pH of 6.0~7.0, and contact time of 60 min. The ads

APA, Harvard, Vancouver, ISO, and other styles

4

Esakkiraja, Neelamegan, Keerti Pandey, Anuj Dash, and Aloke Paul. "Pseudo-binary and pseudo-ternary diffusion couple methods for estimation of the diffusion coefficients in multicomponent systems and high entropy alloys." Philosophical Magazine 99, no. 18 (2019): 2236–64. http://dx.doi.org/10.1080/14786435.2019.1619027.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Esakkiraja, Neelamegan, and Aloke Paul. "A novel concept of pseudo ternary diffusion couple for the estimation of diffusion coefficients in multicomponent systems." Scripta Materialia 147 (April 2018): 79–82. http://dx.doi.org/10.1016/j.scriptamat.2018.01.002.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Leaist, Derek G., and Robert A. Noulty. "An eigenvalue method for determination of multicomponent diffusion coefficients. Application to NaOH + NaCl + H2O mixtures." Canadian Journal of Chemistry 63, no. 2 (1985): 476–82. http://dx.doi.org/10.1139/v85-077.

Full text

Abstract:

A general method for the determination of multicomponent diffusion coefficients is developed using the algebraic technique of matrix diagonalization. When linear combinations of measurements from several multicomponent diffusion experiments performed with different initial concentration gradients (but with the same final composition) are analyzed as simple binary data, particular combinations may be found that transform the multicomponent diffusion coefficient matrix D to diagonal form and thus yield time-invariant, pseudo-binary diffusion coefficients: the eigenvalues of D. Since the matrix t

APA, Harvard, Vancouver, ISO, and other styles

7

Barros, Marisa C. F., Ana C. F. Ribeiro, Luís M. P. Verissimo, Derek G. Leaist та Miguel A. Esteso. "Diffusion in ternary aqueous {L-dopa + (NaSO3) -β-cyclodextrin} solutions using the pseudo-binary approximation". Journal of Chemical Thermodynamics 123 (серпень 2018): 17–21. http://dx.doi.org/10.1016/j.jct.2018.03.014.

Full text

APA, Harvard, Vancouver, ISO, and other styles

8

Al Saqr, Ahmed, Manjusha Annaji, Ishwor Poudel, et al. "Topical Delivery of Diacetyl Boldine in a Microemulsion Formulation for Chemoprotection against Melanoma." Pharmaceutics 15, no. 3 (2023): 901. http://dx.doi.org/10.3390/pharmaceutics15030901.

Full text

Abstract:

This study aimed to develop a microemulsion formulation for topical delivery of Diacetyl Boldine (DAB) and to evaluate its cytotoxicity against melanoma cell line (B16BL6) in vitro. Using a pseudo-ternary phase diagram, the optimal microemulsion formulation region was identified, and its particle size, viscosity, pH, and in vitro release characteristics were determined. Permeation studies were performed on excised human skin using Franz diffusion cell assembly. The cytotoxicity of the formulations on B16BL6 melanoma cell lines was evaluated by MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-

APA, Harvard, Vancouver, ISO, and other styles

9

Sonule, Minal, Lalchand D. Devhare, M. Niranjan Babu, Sachinkumar D. Gunjal, and S. Varalaxmi. "Microemulgel-based Hydrogel of Diclofenac Sodium using Lipidium sativum as a Gelling Agent." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 13, no. 04 (2023): 1235–39. http://dx.doi.org/10.25258/ijddt.13.4.19.

Full text

Abstract:

Aim was to prepare hydrogel containing diclofenac sodium using Lipidium sativum as a gelling agent within a micro emulsion-based system. The oil phase consisted of soybean oil, while surfactants, namely Span 80 and Tween 20, were employed in the formulation. Absolute ethanol was used as a co-surfactant and were characterized by a phase diagram. The in-vitro permeation information is derived from the Franz diffusion. Different microemulsion was designed by screening of various components by performing pseudo-ternary phase diagram and then a solubility study. From this psudo-ternary phase diagra

APA, Harvard, Vancouver, ISO, and other styles

10

Patel, Swati, Prabhat Jain, and Geeta Parkhe. "FORMULATION AND EVALUATION OF ACYCLOVIR LOADED NOVEL NANO-EMULSION GEL FOR TOPICAL TREATMENT OF HERPES SIMPLEX VIRAL INFECTIONS." Journal of Drug Delivery and Therapeutics 8, no. 5-s (2018): 265–70. http://dx.doi.org/10.22270/jddt.v8i5-s.1968.

Full text

Abstract:

Acyclovir has low bioavailability mainly due to low solubility. This study aimed to formulate an optimized acyclovir (ACV) nanoemulsion gel for the slow, variable and incomplete oral drug absorption in patient suffering from herpes simplex viral infection. The dispersion solubility of acyclovir was studied in various oils, surfactants and co-surfactants and by constructing pseudo phase ternary diagram nanoemulsion area was identified. The optimized formulations of nanoemulsions were subjected to thermodynamic stability tests. After stability study, stable formulation was characterized for drop

APA, Harvard, Vancouver, ISO, and other styles

11

Siddiqui, Ayesha, Pooja Jain, Thompson Santosh Alex, et al. "Investigation of a Minocycline-Loaded Nanoemulgel for the Treatment of Acne Rosacea." Pharmaceutics 14, no. 11 (2022): 2322. http://dx.doi.org/10.3390/pharmaceutics14112322.

Full text

Abstract:

In the present investigation, a nanoemulgel of minocycline was formulated and optimized for an improved drug delivery and longer retention time in the targeted area. Combining eucalyptus oil, Tween 20, and Transcutol HP, different o/w nanoemulsions were formulated by the oil phase titration method and optimized by pseudo-ternary phase diagrams. The morphology, droplet size, viscosity, and refractive index of the thermodynamically stable nanoemulsion were determined. Furthermore, optimized nanoemulsion was suspended in 1.0% w/v of Carbopol 940 gel to formulate the nanoemulgel, and for this, pH,

APA, Harvard, Vancouver, ISO, and other styles

12

Areses-Huete, Teresa, Damian Cordoba-Diaz, Ana Isabel Torres-Suárez, and Manuel Cordoba-Diaz. "Development and Characterization of a Microemulsion Containing a Cannabidiol Oil and a Hydrophilic Extract from Sambucus ebulus for Topical Administration." Pharmaceutics 16, no. 6 (2024): 705. http://dx.doi.org/10.3390/pharmaceutics16060705.

Full text

Abstract:

Cannabidiol (CBD) is a safe and non-psychotropic phytocannabinoid with a wide range of potential therapeutic anti-inflamatory and antioxidant activities. Due to its lipophilicity, it is normally available dissolved in oily phases. The main aim of this work was to develop and characterize a new formulation of a microemulsion with potential anti-inflammatory and antioxidant activity for the topical treatment of inflammatory skin disorders. The microemulsion system was composed of a 20% CBD oil, which served as the hydrophobic phase; Labrasol/Plurol Oleique (1:1), which served as surfactant and c

APA, Harvard, Vancouver, ISO, and other styles

13

Tole, Karishma, and Ganesh Deshmukh. "DESIGN AND CHARACTERIZATION OF MICROEMULSION GEL FOR TRANSDERMAL DRUG DELIVERY SYSTEM OF DULOXETINE HYDROCHLORIDE." Asian Journal of Pharmaceutical and Clinical Research 11, no. 11 (2018): 157. http://dx.doi.org/10.22159/ajpcr.2018.v11i11.27552.

Full text

Abstract:

Objective: The objective was to improve the bioavailability, stability of formulation, and skin permeability of Duloxetine HCl.Method: Microemulsion was prepared with oleic acid as oil, water, and Smix ratio of tween 20 to propylene glycol (1:3). Pseudo-ternary phase diagrams were constructed to determine the region of existence of microemulsions prepared using oil titration method. Optimization of formulations was done based on the in vitro diffusion studies. The microemulsion was gelled using carbopol 934p and HPMCK 100 as the gelling agent.Result: After the analysis of different evaluation

APA, Harvard, Vancouver, ISO, and other styles

14

Fu, Lili, Kun Liu, Jinyu Yang, et al. "Adsorption Behaviors of ctDNA and Biological Activities Based on Polyvinyl Alcohol/Polyethylene Glycol/Quaternized Chitosan Composite Hydrogel." Molecules 29, no. 23 (2024): 5770. https://doi.org/10.3390/molecules29235770.

Full text

Abstract:

In this study, a polyvinyl alcohol/polyethylene glycol/hydroxypropyltrimethyl ammonium chloride chitosan (PVA/PEG/HACC) ternary composite hydrogel was synthesized using electron-beam radiation. The materials were thoroughly characterized via Fourier transform infrared spectroscopy, X-ray diffraction, scanning electron microscopy, thermogravimetric analysis, Brunauer–Emmett–Teller analysis, gelation fraction tests, and swelling rate tests. Systematic adsorption experiments revealed that the rate of adsorption of calf thymus DNA (ctDNA) by the PVA/PEG/HACC hydrogel reached 89%. The adsorption pr

APA, Harvard, Vancouver, ISO, and other styles

15

Bharade, Shweta, Naveen Gupta, Shailesh Jain, Vishal Kapoor, and Dharmendra Singh Rajpoot. "Development of Micro-Emulsion Gel Based Topical Delivery of Salicylic Acid and Neem Oil for the Management of Psoriasis." Journal of Drug Delivery and Therapeutics 9, no. 4 (2019): 186–91. http://dx.doi.org/10.22270/jddt.v9i4.3023.

Full text

Abstract:

Microemulsions (MEs) are clear, thermodynamically stable systems. They were used to solubilise drugs and to improve topical drug availability. Salicylic acid (SA) is a keratolytic agent used in topical products with antimicrobial actions. This study aimed to formulate an optimized SA micro emulsion gel for the slow, variable and incomplete oral drug absorption in patient suffering from psoriasis infection. The dispersion solubility of SA was studied in various oils, surfactants and co-surfactants and by constructing pseudo phase ternary diagram, micro emulsion area was identified. The optimize

APA, Harvard, Vancouver, ISO, and other styles

16

Ghazwani, Mohammed, Rajalakshimi Vasudevan, Geetha Kandasamy, et al. "Formulation of Intranasal Mucoadhesive Thermotriggered In Situ Gel Containing Mirtazapine as an Antidepressant Drug." Gels 9, no. 6 (2023): 457. http://dx.doi.org/10.3390/gels9060457.

Full text

Abstract:

The purpose of the present work was to develop nanoemulsion-based formulations of mirtazapine for intranasal delivery using a spray actuator to target the brain for treating depression. Research on the solubility of medications in different oils, surfactants, co-surfactants, and solvents has been done. Using pseudo-ternary phase diagrams, the various ratios of the surfactant and co-surfactant mix were computed. Thermotriggered nanoemulsion was formulated using different concentrations of poloxamer 407 (i.e., 15%, 15.5%, 16%, 16.5% up to 22%). Similarly, mucoadhesive nanoemulsion using 0.1% Car

APA, Harvard, Vancouver, ISO, and other styles

17

Bindhani, Sabitri, Snehamayee Mohapatra, and Rajat Kumar Kar. "Vegetable Oil-Based Self-Microemulsifying Drug Delivery System of Eprosartan Mesylate: in vitro and ex vivo Evaluation." Asian Journal of Chemistry 33, no. 9 (2021): 2182–90. http://dx.doi.org/10.14233/ajchem.2021.23288.

Full text

Abstract:

This study was planned to increase the intestinal permeability and thereby bioavailability of eprosartan mesylate (EPM) by designing a self-microemulsifying drug delivery system (SMEDDS) by the use of vegetable oils. Various SMEDDS-based formulations were prepared with oleic acid and peppermint oil. Tween 80 was used as surfactant and PEG 400 as co-surfactant. Pseudo ternary phase diagrams were constructed for identifying emulsification region between 1:1, 1:2, 2:1, 3:1 ratio of SCOS mix. Eight batches of SMEDDS were found to be thermodynamically stable and from which SMEDDSOF9 and PF5 were be

APA, Harvard, Vancouver, ISO, and other styles

18

Zhao, Zhi-Juan, Xiao-Dong Cui, Xiao-Li Ma, and Zhuan-Hua Wang. "Formulation of a Self-Nanoemulsifying Drug Delivery System of Buckwheat Flavonoids and Evaluation of Its Antimicrobial Activity." Journal of Nanoscience and Nanotechnology 21, no. 5 (2021): 3050–58. http://dx.doi.org/10.1166/jnn.2021.19080.

Full text

Abstract:

This study was aimed at constructing a self-nanoemulsifying drug delivery system of buckwheat flavonoids and evaluating its antimicrobial activity. The construction of the nanoemulsion followed a pseudo-ternary phase diagram, and its particle properties (particle size, zeta potential, and surface morphology) and physicochemical parameters (turbidity, surface tension, pH value, conductivity, encapsulation efficiency, and stability) were evaluated. The antimicrobial potential of buckwheat flavonoids nanoemulsion was determined against Staphylococcus aureus, Escherichia coli, and Candida albicans

APA, Harvard, Vancouver, ISO, and other styles

19

Dash, Anuj, Saswata Bhattacharyya, and Aloke Paul. "Concepts for estimating all types of diffusion coefficients of NiCoFeCr multi-principal element alloys using two dissimilar or a combination of ideal and non-ideal pseudo-ternary diffusion couples." Scripta Materialia 237 (December 2023): 115719. http://dx.doi.org/10.1016/j.scriptamat.2023.115719.

Full text

APA, Harvard, Vancouver, ISO, and other styles

20

Bhattacharya, Sankha, and Bhupendra G. Prajapati. "FORMULATION AND OPTIMIZATION OF CELECOXIB NANOEMULGEL." Asian Journal of Pharmaceutical and Clinical Research 10, no. 8 (2017): 353. http://dx.doi.org/10.22159/ajpcr.2017.v10i8.19510.

Full text

Abstract:

Objective: The main objective of this experiment was to prepare and optimized celecoxib nanoemulgel. This formulation can be used for acuterheumatoid arthritis patients.Methods: Celecoxib is a poorly water soluble drug. We prepared celecoxib nanoemulgel to improve intrinsic solubility of celecoxib and enhancedeeper permeation throughout the skin. After several screening, the combination of acetonitrile, triacetin, campul 908P was considered for oil phase;acconon MC8-2EP as surfactant, and capmul MCM C-10 as a co-surfactant accordingly. As per Box-Behnken surface design model, optimization wasd

APA, Harvard, Vancouver, ISO, and other styles

21

Shen, Jia-Chao, Hong-Yan Zeng, Bi Foua Claude Alain Gohi, and Chao-Rong Chen. "Adsorption Behaviour of Cr(VI) from Ternary Mesoporous Mg/Fe/Al Oxide Using Glucose as a Soft Template." Journal of Nanoscience and Nanotechnology 20, no. 9 (2020): 5555–62. http://dx.doi.org/10.1166/jnn.2020.17875.

Full text

Abstract:

The ternary mesoporous MgFeAl oxide (MgFeAlO) material was designed and prepared using glucose as a soft template by calcination of its MgFeAl hydrotalcite precursor. The MgFeAlO showed significantly better Cr(VI) adsorption performance than binary MgAlO. The effect of Fe3+ on Cr(VI) removal in simulated wastewater was studied by researching the microstructure, adsorption properties and mechanism of the material. The results showed that the addition of Fe3+ affected the microstructure of MgAlO, where the partial substitution of Al3+ by Fe3+ into the host layers resulted in an increase in the i

APA, Harvard, Vancouver, ISO, and other styles

22

H M, Raghu Kumar, and Parthiban S. "DEVELOPMENT OF LEVOFLOXACIN LOADED MICROEMULSION FORMULATED WITH MUSTARD OIL." Journal of Pharmaceutical and Scientific Innovation 10, no. 3 (2021): 87–93. http://dx.doi.org/10.7897/2277-4572.103210.

Full text

Abstract:

The aim of the current study is to develop Levofloxacin loaded microemulsion formulated with mustard oil for better skin penetration effect and to obtain combined effect of both the oil and the drug to improve the efficacy with a reduced dose. Primarily we developed a pseudo ternary phase diagrams to find out the region of microemulsion formation zone by using oil (mustard oil), surfactant (Tween 20 and Tween 80), and co-surfactant (propylene glycol) by water titration method. We formulated six different formulations (MM1-MM6) by varying the concentrations of the oil water and surfactant and c

APA, Harvard, Vancouver, ISO, and other styles

23

K M, Pavankumar, and Parthiban S. "DESIGN AND CHARACTERIZATION OF FLUCONAZOLE MICROEMULSION FORMULATED WITH LEMONGRASS OIL." Journal of Pharmaceutical and Scientific Innovation 10, no. 3 (2021): 80–86. http://dx.doi.org/10.7897/2277-4572.103209.

Full text

Abstract:

The goal of the current investigation is to formulate Fluconazole loaded microemulsion (ME) with Lemongrass oil for deeper skin penetration and to obtain the dual benefit of drug and oil combination to improve antifungal efficacy of a drug with a reduced dose. We developed a Pseudo ternary phase diagram to identify the microemulsion zone by using the oil (clove oil), surfactant (Tween 20 and Tween 80), and co-surfactant (Propylene glycol) by water titration method. We formulated six different formulations (LM1 – LM6) by changing the oil/surfactant and cosurfactant ratio. The developed microemu

APA, Harvard, Vancouver, ISO, and other styles

24

Al-Suwaytee, Safaa Halool Mohammed, Olfa Ben Hadj Ayed, Raja Chaâbane-Banaoues, et al. "Exploring the Antifungal Effectiveness of a Topical Innovative Formulation Containing Voriconazole Combined with Pinus sylvestris L. Essential Oil for Onychomycosis." Colloids and Interfaces 8, no. 5 (2024): 56. http://dx.doi.org/10.3390/colloids8050056.

Full text

Abstract:

(1) Background: The present study aimed to assess the antifungal effectiveness of a topical innovative formulation containing the association of an antifungal agent, voriconazole (VCZ), and the essential oil of Pinus sylvestris L. (PSEO). (2) Methods: Pseudo-ternary phase diagram and D-optimal mixture design approaches were applied for the development and the optimization of the o/w nanoemulsion. The optimized formulation (NE) was subjected to physicochemical characterization and to physical stability studies. In vitro permeation studies were carried out using the Franz cell diffusion system.

APA, Harvard, Vancouver, ISO, and other styles

25

Yang, Ting-Lun, Chien-Ming Hsieh, Ling-Jei Meng, Tsuimin Tsai, and Chin-Tin Chen. "Oleic Acid-Based Self Micro-Emulsifying Delivery System for Enhancing Antifungal Activities of Clotrimazole." Pharmaceutics 14, no. 3 (2022): 478. http://dx.doi.org/10.3390/pharmaceutics14030478.

Full text

Abstract:

Due to the increasing rate of drug resistance in Candida spp., higher doses of antifungal agents are being used resulting in toxicity. Drug delivery systems have been shown to provide an effective approach to enhance the efficacy and reduce the toxicity of antifungal agents. Oleic acid was revealed to effectively inhibit biofilm formation, hence reducing the virulence of Candida albicans. In this study, oleic acid-based self micro-emulsifying delivery systems (OA-SMEDDS) were developed for delivering clotrimazole (CLT). Based on the pseudo-ternary phase diagram and loading capacity test, the o

APA, Harvard, Vancouver, ISO, and other styles

26

Harwansh, Ranjit Kumar, Kartik Chandra Patra, Surendra Kumar Pareta, Jagadish Singh, and Mohammed Akhlaquer Rahman. "Nanoemulsions as vehicles for transdermal delivery of glycyrrhizin." Brazilian Journal of Pharmaceutical Sciences 47, no. 4 (2011): 769–78. http://dx.doi.org/10.1590/s1984-82502011000400014.

Full text

Abstract:

The present investigation aims to evaluate an isotropic and thermodynamically stable nanoemulsion formulation for transdermal delivery of glycyrrhizin (GZ), with minimum surfactant and cosurfactant (Smix) concentrations that could improve its solubility, permeation enhancement, and stability. Pseudo-ternary phase diagrams were developed and various nanoemulsion formulations were prepared using soyabean oil as oil, Span 80, Brij 35 as a surfactant and isopropyl alcohol as a cosurfactant. Nanoemulsion formulations that passed the thermodynamic stability tests were characterized for pH, viscosity

APA, Harvard, Vancouver, ISO, and other styles

27

Bedse, Anjali, Ajinath Nikam, Aditi Kulkarni, Vaishali Potnis, and Suchita Dhamane. "Development and Characterization of topical microemulsion as novel drug delivery system for Dapsone." International Journal of Pharmaceutical Sciences and Nanotechnology 15, no. 1 (2022): 5805–12. http://dx.doi.org/10.37285/ijpsn.2022.15.1.8.

Full text

Abstract:

Dapsone is a Biopharmaceutical Classification System class II drug with anti inflammatory, immunosuppressive, antibacterial, and antibiotic properties and is used as an antileprotic. The purpose of the present study was to investigate the potential of a microemulsion formulation for topical delivery of dapsone to enhance permeation and to avoid systemic side effects. When administered orally, dapsone undergoes hepatic metabolism. Its hepatic metabolite, dapsone hydroxylamine, shows systemic side effects such as hemolytic anaemia peripheral neuropathy, nausea, and headache. A novel drug deliver

APA, Harvard, Vancouver, ISO, and other styles

28

Jeong, Ju-Hwan, Tae-Han Yoon, Si-Won Ryu, et al. "Quality by Design (QbD)-Based Development of a Self-Nanoemulsifying Drug Delivery System for the Ocular Delivery of Flurbiprofen." Pharmaceutics 17, no. 5 (2025): 629. https://doi.org/10.3390/pharmaceutics17050629.

Full text

Abstract:

Objectives: In this study, Quality by Design (QbD) was used to develop an optimized self-nanoemulsifying drug delivery system (SNEDDS) as an ophthalmic formulation of flurbiprofen (FLU). Using a Box–Behnken design (BBD), an optimal SNEDDS composition was crafted, targeting enhanced corneal permeability and increased bioavailability of the drug. Methods: The levels of each factor(X) were established using a pseudo-ternary diagram, and the Box-Behnken design (BBD) was used to evaluate the components of oil (18.9 mg), surfactant (70.7 mg), and co-surfactant (10.0 mg) to optimize the SNEDDS formul

APA, Harvard, Vancouver, ISO, and other styles

29

Sabitri Bindhani, Snehamayee Mohapatra, Rajat Ku. Kar, and Utkalika Mahapatra. "Preparation of self micro emulsifying drug delivery system(smedds) of poorly soluble drug eprosartan mesylate and its in vitro evaluation." International Journal of Research in Pharmaceutical Sciences 10, no. 4 (2019): 3304–14. http://dx.doi.org/10.26452/ijrps.v10i4.1636.

Full text

Abstract:

Eprosartan Mesylate (EM), an angiotensin II receptor blocker used in the treatment of high blood pressure. But poor solubility and bioavailability (13%) of eprosartan mesylate is a major challenging factor for improving its drug release rate. The main objective of the present work to develop and characterize self micro emulsifying drug delivery system of eprosartan mesylate by using compatible oil, surfactant and co-surfactant. For the selection of oil, surfactant and cosurfactant, solubility screening studies has been carried out. The nine formulations are prepared using peppermint oil, tween

APA, Harvard, Vancouver, ISO, and other styles

30

Shafie, Mohamed A. Attia, Maha Abdel-Azeem Hassan Mohamed, and Ahmed Abd-El Zaher Saadi Mohamed. "Topical Delivery of Voriconazole Loaded on Lyotropic Liquid Crystal Gel for Management of Fungal Infections." Journal of Pharmaceutical Research 23, no. 2 (2024): 89–106. http://dx.doi.org/10.18579/jopcr/v23.2.32.

Full text

Abstract:

Topical antifungal therapy is recommended for the treatment of fungal infections of the skin. Due to its benefits, including the ability to direct drugs to the infection site and a lower chance of systemic adverse effects. The nano size and structure of LLC with the skin enhance the permeation and deposition of drugs within deep parts of skin. In this a novel formulation of voriconazole LLC gel was planned. Surfactant, co-surfactant, oil, and water pseudo-ternary phase diagrams were created in order to determine the LLC gel and microemulsion zones. The formulations were evaluated using polariz

APA, Harvard, Vancouver, ISO, and other styles

31

Jantrawut, Pensak, Kasidech Boonsermsukcharoen, Kanyanut Thipnan, Tanpong Chaiwarit, Kyu-Mok Hwang, and Eun-Seok Park. "Enhancement of Antibacterial Activity of Orange Oil in Pectin Thin Film by Microemulsion." Nanomaterials 8, no. 7 (2018): 545. http://dx.doi.org/10.3390/nano8070545.

Full text

Abstract:

The purpose of this study was to prepare orange oil microemulsion (ME) and to investigate the antimicrobial activity of film containing orange oil ME. First, surfactants and co-surfactants were screened on their efficiency to form ME using pseudo-ternary phase diagrams. The influences of surfactant and co-surfactant mass ratios were studied and optimized ME-loaded-films were prepared. Then, films containing orange oil ME were characterized by SEM and texture analyzer, and then evaluated for antimicrobial activity against Staphylococcus aureus and Propionibacterium acnes using an agar disc diff

APA, Harvard, Vancouver, ISO, and other styles

32

Bindhani, Sabitri, Utkalika Mohapatra, Snehamayee Mohapatra, and Rajat K. Kar. "Enhancement of Solubility and Dissolution Rate of Poorly Soluble Drug Nifedipine by Solid Sedds." International Journal of Drug Delivery Technology 10, no. 01 (2020): 9–15. http://dx.doi.org/10.25258/ijddt.10.1.3.

Full text

Abstract:

Nifedipine is a dihydropyridine calci channel blocking agent belongs to biopharmaceutical classification system (BCS) class-II mainly applied in the treatment of hypertension and angina-pectoris. The objective of this work is to improve the solubility and dissolution rate of nifedipine by formulating into a solid-self micro emulsifying drug delivery system (solid smedds). Methods: Oil, Surfactant, and cosurfactant were selected by solubility screening study. For the determination of the best emulsion region, a pseudo ternary diagram was prepared. Based on solubility castor oil, tween 80 and po

APA, Harvard, Vancouver, ISO, and other styles

33

Venkatachalam, Abhirami, Harini Chowdary Vadlamudi, and Sneha Bharti. "Factorial Design Executed Development of Miconazole Nitrate Microemulsion Based Bioadhesive Gel and Its Evaluation." International Journal of Research and Review 9, no. 1 (2022): 574–87. http://dx.doi.org/10.52403/ijrr.20220167.

Full text

Abstract:

Miconazole nitrate (MN) is a poorly aqueous soluble antifungal drug. The microemulsion (ME) based bioadhesive antifungal gel of MN was designed to improve the antifungal activity by increasing the bioadhesion potential. Based on the solubility results, components of ME were selected viz. rice bran oil: tween 80: propylene glycol and proceeded with pseudo-ternary phase diagram studies. 23 factorial design was employed for the formulation of MEs employing water titration technique. The MEs was examined for further studies and was optimized using DESIGN EXPERT 12 software considering the response

APA, Harvard, Vancouver, ISO, and other styles

34

Ashara, Kalpesh C., and Ketan V. Shah. "Emulsion of Chloramphenicol: an Overwhelming Approach for Ocular Delivery." Folia Medica 59, no. 1 (2017): 23–30. http://dx.doi.org/10.1515/folmed-2017-0007.

Full text

Abstract:

Abstract Background: Ophthalmic formulations of chloramphenicol have poor bioavailability of chloramphenicol in the ocular cavity. Aim: The present study aimed at exploring the impact of different oil mixtures in the form of emulsion on the permeability of chloramphenicol after ocular application. Materials and methods: Selection of oil mixture and ratio of the components was made by an equilibrium solubility method. An emulsifier was chosen according to its emulsification properties. A constrained simplex centroid design was used for the assessment of the emulsion development. Emulsions were

APA, Harvard, Vancouver, ISO, and other styles

35

Mehreen Sattar, Somia Sarfraz, Uzma Liaquat, Iqra Shoukat, Bilal Ahmad, and Talib Hussain. "Formulation and evaluation of topical piroxicam microemulgel for arthritis." Journal of Contemporary Pharmacy 7, no. 1 (2023): 16–23. http://dx.doi.org/10.56770/jcp2023713.

Full text

Abstract:

Background: Piroxicam is an anti-inflammatory, analgesic, and antipyretic drug. Piroxicam is widely used in the management of chronic pain. The objective of this work was to develop and analyze topical Piroxicam microemulgel to improve drug solubility, enhance permeation, reduce GIT side effects reduce the frequency of the drug. Method: The Piroxicam microemulgel was prepared by drawing the pseudo ternary phase picture and water titration procedure. Formulation was prepared by using isopropyl myristate as an oil, Tween 80 as an surfactant, n-butanol as Co-surfactant and water. It was converted

APA, Harvard, Vancouver, ISO, and other styles

36

Sattar, Mehreen, Somia Sarfraz, Uzma Liaquat, Iqra Shoukat, Bilal Ahmad, and Talib Hussain. "Formulation and evaluation of topical piroxicam microemulgel for arthritis." Journal of Contemporary Pharmacy 7, no. 1 (2023): 16–23. http://dx.doi.org/10.56770/jcp.2023713.

Full text

Abstract:

Background: Piroxicam is an anti-inflammatory, analgesic, and antipyretic drug. Piroxicam is widely used in the management of chronic pain. The objective of this work was to develop and analyze topical Piroxicam microemulgel to improve drug solubility, enhance permeation, reduce GIT side effects reduce the frequency of the drug. Method: The Piroxicam microemulgel was prepared by drawing the pseudo ternary phase picture and water titration procedure. Formulation was prepared by using isopropyl myristate as an oil, Tween 80 as an surfactant, n-butanol as Co-surfactant and water. It was converted

APA, Harvard, Vancouver, ISO, and other styles

37

Vaidya, Vrushali Kashinath *. Ambekar Abdul Wahid. "FORMULATION, DEVELOPMENT AND EVALUATION OF EUGENOL OIL NANOEMULSION GEL FOR TOPICAL DELIVERY." Journal of Pharma Research 8, no. 8 (2019): 584–94. https://doi.org/10.5281/zenodo.3374095.

Full text

Abstract:

<strong><em>ABSTRACT</em></strong> <strong><em>T</em></strong><em>he aim of the present work was to formulate and characterized the nanoemulsion based gel for poorly water soluble eugenol oil in order to overcome the side-effects associated with its oral delivery. Pseudo-ternary phase diagrams were constructed using titration method. Various components of nanoemulsion were selected on the basis of compatibility study, solubility study and emulsification ability. Nanoemulsion was formulated by ultra-sonication method and characterized for droplet size, poldispersity index, zeta potential, rheol

APA, Harvard, Vancouver, ISO, and other styles

38

Nagaraja, Sreeharsha, Girish Meravanige Basavarajappa, Mahesh Attimarad, and Swati Pund. "Topical Nanoemulgel for the Treatment of Skin Cancer: Proof-of-Technology." Pharmaceutics 13, no. 6 (2021): 902. http://dx.doi.org/10.3390/pharmaceutics13060902.

Full text

Abstract:

The present study is a mechanistic validation of ‘proof-of-technology’ for the effective topical delivery of chrysin nanoemulgel for localized, efficient treatment of melanoma-affected skin. Background: Currently available treatments for skin cancer are inefficient due to systemic side effects and poor transcutaneous permeation, thereby presenting a formidable challenge for the development of novel nanocarriers. Methods: We opted for a novel approach and formulated a nanocomplex system composed of hydrophobic chrysin dissolved in a lipid mix, which was further nanoemulsified in Pluronic® F-127

APA, Harvard, Vancouver, ISO, and other styles

39

Gohel, Mukesh, Ankita Purohit, Asha Patel, and Lal Hingorani. "OPTIMIZATION OF BACOSIDE A LOADED SNEDDS USING D-OPTIMAL MIXTURE DESIGN FOR ENHANCEMENT INSOLUBILITY AND BIOAVAILABILITY." International Journal of Pharmacy and Pharmaceutical Sciences 8, no. 12 (2016): 213. http://dx.doi.org/10.22159/ijpps.2016v8i12.13488.

Full text

Abstract:

<p><strong>Objective</strong>:<strong> </strong>The objective of present study is to enhance solubility and bioavailability of poorly soluble <em>bacoside A</em> present in <em>Bacopa monnieri</em> extract using self nano emulsifying drug delivery system (SNEDDS) for the treatment of Alzheimer's disease.</p><p><strong>Methods: </strong>Solubility of the drug was assessed in various oils (edible as well as synthetic oil), surfactant and co-surfactant by saturation solubility study. Pseudo-ternary phase diagram was use

APA, Harvard, Vancouver, ISO, and other styles

40

Jiang, Kui, Jie Zhang, Zhengxing Peng, et al. "Pseudo-bilayer architecture enables high-performance organic solar cells with enhanced exciton diffusion length." Nature Communications 12, no. 1 (2021). http://dx.doi.org/10.1038/s41467-020-20791-z.

Full text

Abstract:

AbstractSolution-processed organic solar cells (OSCs) are a promising candidate for next-generation photovoltaic technologies. However, the short exciton diffusion length of the bulk heterojunction active layer in OSCs strongly hampers the full potential to be realized in these bulk heterojunction OSCs. Herein, we report high-performance OSCs with a pseudo-bilayer architecture, which possesses longer exciton diffusion length benefited from higher film crystallinity. This feature ensures the synergistic advantages of efficient exciton dissociation and charge transport in OSCs with pseudo-bilaye

APA, Harvard, Vancouver, ISO, and other styles

41

Sadhu, Suman, Anuj Dash, Neelamegan Esakkiraja, et al. "Practicing pseudo-binary diffusion couple method in ternary and multicomponent systems." Acta Materialia, May 2025, 121127. https://doi.org/10.1016/j.actamat.2025.121127.

Full text

APA, Harvard, Vancouver, ISO, and other styles

42

Patil, Vishwambhar S., MD Shamshuddin, Pooja P. Humane, et al. "Mixed convective flow of Casson magneto-trihybrid nanofluid with Cattaneo–Christov heat fluxing and Ohmic heating: Applying pseudo-spectral collocation method." Modern Physics Letters B, March 19, 2025. https://doi.org/10.1142/s0217984925501374.

Full text

Abstract:

This study focuses on examining the magnetized bioconvection flow of Casson ternary nanofluid. The mathematical modeling is developed considering Cattaneo–Christov double diffusion (CCDD), Joule heating, and viscous dissipative effects. The Cattaneo–Christov heat flux model is employed to account for finite thermal relaxation time, which addresses limitations of the conventional Fourier’s law by capturing non-instantaneous heat propagation and magnetic responsive boundary conditions considered. The transformation of the governing equations is done using a group of similarity variables. The red

APA, Harvard, Vancouver, ISO, and other styles

43

Kitada, Atsushi, Kio Kawata, Kazuhiro Fukami, and Kuniaki Murase. "A Pseudo Hydronium Solvate Ionic Liquid and Taxonomy of the Allied Protic Media." Chemistry – An Asian Journal, June 24, 2025. https://doi.org/10.1002/asia.202500146.

Full text

Abstract:

AbstractA ternary equimolar mixture of water, 18‐crown‐6‐ether (18C6), and (+)‐10‐camphorsulfonic acid (CSA), [H2O]/[18C6]/[CSA] = 1/1/1 by mole, has been prepared and characterized as a “pseudo hydronium solvate ionic liquid (IL).” In this system, 18C6‐coordinated water is only partially protonated by CSA, resulting in a coexistence of 18C6‐solvated hydronium (H3O+) ions and neutral [H2O·18C6] complexes. Unlike previously reported protic media formed with superacids, which undergo complete proton transfer to form solvate ILs, this system retains a significant fraction of neutral species due t

APA, Harvard, Vancouver, ISO, and other styles

44

Chaturvedi, Priyanka, and Praveen Sharma. "Evaluation of the in-vitro antifungal activity of Holoptelea Integrifolia ethanolic extract loaded in microemulsion." EJPPS EUROPEAN JOURNAL OF PARENTERAL AND PHARMACEUTICAL SCIENCES, July 28, 2023. http://dx.doi.org/10.37521/ejpps.28202.

Full text

Abstract:

Microemulsions improve the transdermal delivery of several drugs over conventional topical preparations such as emulsions and gels: enhanced drug solubilization, increased skin flux, and decreased diffusion coefficient. Microemulsion-based systems find significant improvement in the topical delivery of antifungals. We believe that drug-loaded microemulsion will show better antifungal activity by better penetration into the skin and fungal cells. Antifungal agents are mostly lipophilic and easily formulated in topical vehicles. Microemulsions were prepared by the phase titration method. Formula

APA, Harvard, Vancouver, ISO, and other styles

45

Mao, Houdong, Jiayou Zhang, Lin Wen, et al. "Controlled Solution Flow via Patterned Meniscus Assist for Elongated Exciton Diffusion Length to Approaching 20% Efficiency in Pseudo‐Planar Heterojunction Organic Solar Cells." Advanced Materials, May 20, 2025. https://doi.org/10.1002/adma.202505266.

Full text

Abstract:

AbstractPrecisely controlling the ideal vertical phase morphology of blade‐coated pseudo‐planar heterojunction (PPHJ) organic photovoltaics presents a key challenge due to Marangoni flow and coffee‐ring effect, which further limits large‐area film uniformity and shortens exciton diffusion length. Here, the patterned meniscus assist (PMA) strategy is used to stretch polymer chains and construct regular micropatterns to facilitate donor/acceptor inter‐penetration, resulting in a high‐performance printable PPHJ device with extended exciton diffusion length (from ≈45 to ≈56 nm). More importantly,

APA, Harvard, Vancouver, ISO, and other styles

46

Kamar, Firas Hashim, Aurelia Cristina Nechifor, Gheorghe Nechifor, Tariq J. Al-Musawi, and Asem Hassan Mohammed. "Aqueous Phase Biosorption of Pb(II), Cu(II), and Cd(II) onto Cabbage Leaves Powder." International Journal of Chemical Reactor Engineering 15, no. 2 (2017). http://dx.doi.org/10.1515/ijcre-2015-0178.

Full text

Abstract:

Abstract In this study, the biosorption of lead (Pb(II)), copper (Cu(II)), and cadmium (Cd(II)) ions from aqueous solution using waste of cabbage leaves powder (CLP) was investigated as a function of pH, shaking time, initial metal concentration, and biosorbent dose. The maximum removal efficiency at optimum condition in single biosorption system was 95.67, 92.42, and 88.92 % for Pb(II), Cu(II), and Cd(II) ions, respectively. These values reduced in ternary systems in the same sequence. Langmuir and extended Langmuir isotherm models were found to be the best fit of the isotherm data for single

APA, Harvard, Vancouver, ISO, and other styles

47

A, Swaroopa, C. Aparna, and Prathima Srinivas. "FORMULATION, EVALUATION AND CHARACTERIZATION OF PERIODONTAL MICROEMULSION GEL." International Journal of Pharmaceutical Sciences and Drug Research, January 1, 2014, 20–25. https://doi.org/10.25004/ijpsdr.2014.060103.

Full text

Abstract:

The aim of the present study was to develop microemulsion gel of Satranidazole for the treatment of periodontitis. The objective was to increase the solubility of Satranidazole, a lipophilic drug and to enhance depth of penetration of the drug into the periodontal pocket for efficacious treatment of periodontitis. Pseudo ternary phase diagrams were constructed to determine the region of existence of microemulsions prepared using cosurfactant titration method. The formulations were developed using isopropyl myristate, tween 80, ethanol; oleic acid, tween 80, propylene glycol; oleic acid, cremop

APA, Harvard, Vancouver, ISO, and other styles

48

Patel, Neelam, Sunita Chaudhary, and Ankit Chaudhary. "Formulation Development and Evaluation of Apremilast Nanoemulsion." Research Journal of Pharmacy and Technology, June 26, 2023, 2859–66. http://dx.doi.org/10.52711/0974-360x.2023.00471.

Full text

Abstract:

Apremilast is a selective phosphodiesterase 4 inhibitor administered orally in the treatment of moderate-to-severe plaque psoriasis and active psoriatic arthritis. It is classified as class IV drug as per BCS classification so it indicates low solubility and lower permeability through the skin. Therefore the objective of the research is to improve permeability of Apremilast through the skin and improve solubility by using oil and surfactant by formulating Nanoemulsion. Nanoemulsion was prepared by selecting Captex 355, Cremophore RH 40, Labrafil and Propylene glycol as the oil, surfactant,co-s

APA, Harvard, Vancouver, ISO, and other styles

49

Ratnparkhi, Mukesh, Prasad Kadam, Ashish Mule, Mayur Markand, Bhagyashri Binawade, and Arshad Shaikh. "Formulation And Evaluation of Diclofenac Sodium-Loaded Self-Microemulsifying Gel for Enhanced Topical Drug Delivery." Journal of Pharmacological and Pharmaceutical Research, 2024, 1. http://dx.doi.org/10.5455/jppr.20240629071651.

Full text

Abstract:

Objective: This study aimed to develop a topical gel formulation of diclofenac sodium (DFS) utilizing a self-micro emulsifying drug delivery system (SMEDDS) to enhance solubility, bioavailability, and patient compliance while minimizing systemic side effects associated with oral administration. Methods: DFS solubility was evaluated in various oils, surfactants, and co-surfactants. A pseudo-ternary phase diagram guided the selection of optimal SMEDDS components. The SMEDDS formulation, comprising cinnamon oil, Tween 20, and propylene glycol, was converted into a gel using Carbopol 940. Both the

APA, Harvard, Vancouver, ISO, and other styles

50

Grifoni, Lucia, Giulia Vanti, Maria Giuliana vannucchi, Maria Camilla Bergonzi, and Anna Rita BILIA. "Development and evaluation of khellin-loaded microemulgel for dermatological applications." Planta Medica, March 4, 2022. http://dx.doi.org/10.1055/a-1789-3112.

Full text

Abstract:

Microemulsions are optically nanosized emulsions, isotropic and thermodynamically stable. They represent versatile drug delivery systems with high potential because can be administered through all routes. In the present study, we report on the formulation of a microemulsion made with glycerol (2.25%), Labrasol (20.25%) vitamin E acetate (2.50%), and water (75.00%), which was developed using the pseudo-ternary phase diagram. Globules of the microemulsion had PdI less than 0.25 and size of about 17 nm, evaluated by DLS analysis. These values did not change after loading khellin, a natural lipoph

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!