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Relevant bibliographies by topics / Pseudotyped virus / Dissertations / Theses

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Dissertations / Theses on the topic 'Pseudotyped virus'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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1

Bentley, Emma. "The study of highly pathogenic emerging zoonotic virus envelope proteins through pseudotyped virus generation." Thesis, University of Westminster, 2017. https://westminsterresearch.westminster.ac.uk/item/q4yzx/the-study-of-highly-pathogenic-emerging-zoonotic-virus-envelope-proteins-through-pseudotyped-virus-generation.

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Emerging zoonotic viruses pose an increasing threat, causing outbreaks with high rates of morbidity and mortality and frequently significant economic implications. Often, there is a lack or shortfall of effective prophylaxis and diagnostic capabilities. Research towards their development, together with improved surveillance activities are high priority activities to prepare and respond to outbreak threats. Yet handling these viruses commonly requires high containment levels. This can be circumvented by the use of replication defective pseudotyped viruses (PVs), incorporating the viral envelope

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2

Grzybowski, Brad. "A pseudotyped viral vector : hPIV3-HIV-1." Thesis, Georgia Institute of Technology, 2003. http://hdl.handle.net/1853/20932.

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3

Mather, Stuart Thomas. "Development of pseudotyped virus assays for the serological study of Japanese encephalitis flavivirus." Thesis, University of Kent, 2017. https://kar.kent.ac.uk/62936/.

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Japanese encephalitis virus (JEV) is one of the primary global causes of viral encephalitis, with approximately 68,000 clinical cases and 20,000 deaths attributed to the virus annually. Between 30% and 50% of survivors suffer from debilitating neurological sequelae. Despite being a vaccine-preventable disease, no antiviral treatments are licensed and commercially available to counteract JEV infection. In order to quantify the neutralising antibody response raised against antigenic epitopes on flavivirus prME glycoproteins, conventional serological assays such as the plaque reduction neutralisa

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4

Mao, Jian. "Vesicular stomatitis virus G pseudotyped retrovector mediated gene delivery of connexin43 to brain tumor cells." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0001/MQ42173.pdf.

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5

Gollan, Timothy J. "Altering the Tropism of Retroviral Vectors For In Vivo Gene Therapy: Pseudotyped Virus Targeting by Ligand-Receptor Interactions: A Dissertation." eScholarship@UMMS, 2002. http://escholarship.umassmed.edu/gsbs_diss/226.

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A potential approach to in vivo gene therapy is to target retrovirus to specific receptors through a ligand-receptor interaction. Previous studies have placed a ligand at or close to the N-terminus of the ecotropic Moloney murine leukemia virus envelope and require co-expression of a wild type envelope on the pseudotyped virus for successful transduction of human cells. In this study, over forty chimeric envelopes were generated, which have single or multiple insertions of a 13 or 21 amino acid RGD containing sequence, flanked by cysteine residues, that target the cellular integrin receptors (

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6

Jäkel, Melanie [Verfasser], and Gerd [Akademischer Betreuer] Sutter. "In vivo characterization of a pseudotyped vesicular stomatitis virus for the treatment of Hepatocellular carcinoma / Melanie Jäkel ; Betreuer: Gerd Sutter." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2020. http://d-nb.info/1206096616/34.

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7

Waern, Johan Martin [Verfasser], and Michael [Akademischer Betreuer] Ott. "Cell-specific infection of human cells mediated by lentiviral vectors pseudotyped with measles virus hemagglutinin fused to single chain antibodies / Johan Martin Waern ; Akademischer Betreuer: Michael Ott ; Klinik für Gastroenterologie, Hepatologie und Endokrinologie der Medizinischen Hochschule Hannover." Hannover : Bibliothek der Medizinischen Hochschule Hannover, 2018. http://d-nb.info/1151400343/34.

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8

Waern, Johan [Verfasser], and Michael [Akademischer Betreuer] Ott. "Cell-specific infection of human cells mediated by lentiviral vectors pseudotyped with measles virus hemagglutinin fused to single chain antibodies / Johan Martin Waern ; Akademischer Betreuer: Michael Ott ; Klinik für Gastroenterologie, Hepatologie und Endokrinologie der Medizinischen Hochschule Hannover." Hannover : Bibliothek der Medizinischen Hochschule Hannover, 2018. http://nbn-resolving.de/urn:nbn:de:gbv:354-2017111580.

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9

Codran, Audrey. "Production de virus pseudotypes VSV/VHC : Etude de la fusion du VHC avec les cellules hôtes." Université Louis Pasteur (Strasbourg) (1971-2008), 2003. https://publication-theses.unistra.fr/public/theses_doctorat/2003/CODRAN_Audrey_2003.pdf.

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En raison de l'absence de système de culture cellulaire capable de propager efficacement le virus de l'hépatite C, peu de données sont disponibles concernant les phases précoces de l'infection. Afin d'étudier la fusion et la pénétration du VHC dans la cellule hôte, nous avons choisi de fabriquer des virus pseudotypes VSV/VHC destinés à mimer l'enveloppe du VHC dans les phases précoces de l'infection. Dans un premier temps, les glycoprotéines d'enveloppe du VHC (E1 et E2) sont modifiées pour être localisées à la membrane plasmique, site de bourgeonnement du VSV. Pour cela, les ectodomaines de E

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10

Pfaff, Kerstin [Verfasser]. "Hepatitis-C-Virus-Pseudotypen und deren Einsetzbarkeit in der virologischen Diagnostik / Kerstin Pfaff." Berlin : Freie Universität Berlin, 2012. http://d-nb.info/1029850569/34.

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11

Le, Goff Jérôme. "Interactions entre le VIH-1 et l' herpes simplex de type 2 dans le microenvironnement cellulaire et génital." Paris 7, 2005. http://www.theses.fr/2005PA077105.

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12

Gagnepain, Anaïs. "Évaluation de nouveaux pseudotypes de vecteurs lentiviraux pour le transfert de gènes dans les cellules hématopoiétiques." Thesis, Lyon, École normale supérieure, 2014. http://www.theses.fr/2014ENSL0939/document.

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Le transfert de gènes dans les cellules souches hématopoïétiques par des vecteurs lentiviraux s’inscrit dans les protocoles actuels de traitement par thérapie génique de plusieurs maladies monogéniques (B-thalassémie, Adrénoleucodystrophie, SCID…). De même, le transfert de gènes dans les lymphocytes T et B ouvre des perspectives tant au niveau de la thérapie génique que pour l’immunothérapie. Nous avons mis au point des vecteurs lentiviraux pseudotypés par des glycoprotéines chimérique (BaEV/TR) et mutante (BaEVRLess) du rétrovirus endogène de babouin. Nous avons montré que ces nouveaux vecteu

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13

Molina, Rosa-Maria. "Facteurs influençant l'expression de vecteurs rétroviraux dérivés des virus ALSV in vitro : rôle des pseudotypes rétroviraux sur la spécificité tissulaire du transfert de gènes intraembryonnaire chez les oiseaux." Lyon 1, 1994. http://www.theses.fr/1994LYO10097.

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Les animaux transgeniques constituent actuellement un modele particulierement adapte pour de nombreuses etudes in vivo tant en recherche fondamentale qu'en recherche appliquee. Les vecteurs mis au point dans notre laboratoire pour transferer des genes exogenes chez les oiseaux sont derives des retrovirus aviaires alsv et produits en condition helper-free. Ils infectent les cellules permissives et l'information genetique qu'ils vehiculent s'integre efficacement dans le genome cellulaire. Cependant, l'expression stable et efficace des genes transferes depend de multiples facteurs. Ce travail a m

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14

Wu, Chia Jen, and 吳嘉仁. "The establishment of pseudotyped adeno-associated virus 2/9-delivered CCL11 shRNA and CC10 gene to alleviate lung inflammation in allergen-sensitized murine model." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/56930458481372748776.

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博士<br>長庚大學<br>生物醫學研究所<br>101<br>Asthma is a chronic airway inflammatory disease characterized by eosinophilic infiltration and airway hyperresponsiveness. The over-activated Th2 and lung epithelial cells express many different cytokines and chemokines that mainly contribute to the severity of lung inflammation. CCL11 (eotaxin-1) is secreted by lung epithelial cells and functions as a major chemokine for eosinophil recruitment. Clara cell 10 kDa protein (CC10) that is highly expressed and secreted from airway epithelial cells and exhibits anti-inflammatory and immunomodulatory effects. Pseudoty

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15

Lin, Po-Yin, and 林柏吟. "Expressing dengue virus 2 E protein for pseudotype formation of murine leukemia virus with dengue virus envelope." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/35241300985270384102.

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碩士<br>國立交通大學<br>生化工程研究所<br>94<br>Dengue virus (DV), a member of the family Flaviviridae, is an enveloped, single-stranded positive sense RNA virus. Dengue fever and dengue hemorrhagic fever (DF/DHF) are caused by the dengue viruses that represent a global public health problem. In the process of virus entry, the envelope protein (E protein) plays an important role. It is a glycoprotein of 495 amino acids, with a transmembrane domain at the C-terminal. The extracellular domain of E protein is thought to interact with the host cell receptor. There is no discernable change in the host cell that i

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