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1
Mallien, Grit. "Explorative multizentrische Querschnittsstudie zur Diagnostik der Dysarthrie bei Progressiver Supranukleärer Blickparese - PSP." Phd thesis, Universität Potsdam, 2011. http://opus.kobv.de/ubp/volltexte/2012/5804/.
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Die Progressive Supranukleäre Blickparese (PSP) ist eine sporadisch auftretende neurodegenerative Erkrankung im Rahmen der atypischen Parkinson-Syndrome (APS), die im frühen Verlauf häufig mit dem Idiopathischen Parkinson-Syndrom (IPS) verwechselt wird. Dabei ist die Dysarthrie als eine erworbene, zentral bedingte sprechmotorische Störung ein häufiges und früh auftretendes Symptom bei PSP. Bislang spricht man von einer eher unspezifischen „gemischten“ Dysarthrie aus hypokinetischen, spastischen und auch ataktischen Komponenten. Im Rahmen einer explorativen Querschnittsstudie am „Fachkrankenhaus für Bewegungsstörungen und Parkinson“ Beelitz-Heilstätten in Kooperation mit der „Entwicklungsgruppe Klinische Neuropsychologie“ München (EKN) sowie der „Interdisziplinären Ambulanz für Bewegungsstörungen“ am Klinikum München-Großhadern wurden 50 Patienten dahingehend untersucht, ob sich für die Progressive Supranukleäre Blickparese (PSP) eine spezielle, frühzeitig zu diagnostizierende und differentialdiagnostisch relevante Dysarthrie beschreiben ließe. In diesem Zusammenhang soll geklärt werden, ob es sich um phänotypische Ausprägungen im Rahmen eines Störungsspektrums handelt oder ob sich differenzierbare Subtypen der Krankheit, insbesondere ein „klassischer“ PSP-Typ (PSP-RS) und ein „atypischer“ PSP-Typ (PSP-P), auch im Bereich der Dysarthrie zeigen.
Im Rahmen der Untersuchungen wurde der Schweregrad der Erkrankung mittels der „PSP-sensitiven Ratingskala (PSPRS)“ gemessen. Die Dysarthriediagnostik erfolgte anhand der „Bogenhausener Dysarthrieskalen (BoDyS)“ zur Beschreibung der Art und Ausprägung der Dysarthrie bei PSP. Die Verständlichkeit wurde mithilfe des „Münchner Verständlichkeits-Profils (MVP)" sowie eines weiteren Transkriptionsverfahrens ermittelt, wobei Ausschnitte aus den Tests zum Lesen und Nachsprechen der BoDyS zugrunde lagen. Weiterhin erfolgte eine Einschätzung der Natürlichkeit des Sprechens. Die Ergebnisse hinsichtlich des Einflusses von Natürlichkeit und Verständlichkeit des Sprechens auf den Schweregrad der Dysarthrie zeigten, dass dieser modalitätenübergreifend mit beiden Schweregradaspekten korreliert, wenngleich es offenbar die Natürlichkeit des Sprechens ist, die bei PSP bereits frühzeitig beeinträchtigt ist und somit als das entscheidende differentialdiagnostische Kriterium zur Differenzierung zwischen beiden PSP-Subtypen zu beurteilen ist, möglicherweise auch gegenüber anderen Parkinson-Syndromen.
Anhand statistisch valider Ergebnisse konnten spezifische Störungsmerkmale der Dysarthrie extrahiert werden, die eine signifikante Trennung von PSP-RS und PSP-P ermöglichen: eine leise und behaucht-heisere Stimme sowie ein verlangsamtes Sprechtempo und Hypernasalität. Damit können für die hier fokussierten Subtypen der PSP zwei unterschiedliche Dysarthrietypen postuliert werden. Danach wird dem Subtyp PSP-RS eine spastisch betonte Dysarthrie mit ausgeprägter Verlangsamung des Sprechtempos zugeordnet, dem Subtyp PSP-P hingegen eine hypokinetische Dysarthrie mit behaucht-heiserer Hypophonie. Desweiteren konnte ein „Dysarthrie-Schwellenwert“ als Zusatzkriterium für eine zeitliche Differenzierung beider PSP-Subtypen ermittelt werden. Anhand der Daten zeigte sich die Dysarthrie bei dem Subtyp PSP-RS gleich zu Beginn der Erkrankung, jedoch spätestens 24 Monate danach. Hingegen konnte die Dysarthrie beim Subtyp PSP-P frühestens 24 Monate nach Erkrankungsbeginn festgestellt werden.
Die Daten dieser Studie verdeutlichen, dass der Frage nach einer subtypenspezifischen Ausprägung der Dysarthrie bei PSP eine Längsschnittsstudie folgen sollte, um die ermittelten Ergebnisse zu konsolidieren.Progressive Supranuclear Palsy (PSP) is an atypical Parkinsonian syndrome characterized by gait ataxia, slowing or inability to generate vertical saccadic eye movements, axial rigidity, cognitive disorders and a progressive dysarthria. The dysarthria may include abnormalities in strength, speed, range, tone or accuracy of speech movements. As the disease progresses, important functional components of speech including respiration, phonation, resonance, articulation and prosody are affected. The question is what kind of dysarthria do we find in PSP? Until now it remains unclear, if the dysarthric characteristics of PSP vary in way as described by Williams et al. (2005) who found clinically distinct symptom patterns of a Parkinsonian form of PSP (PSP-P) distinct from a classical form (Richardson Syndrome). The aim of the cross-sectional multi center study was to investigate the specific dysarthric symptoms in patients with PSP. Until now it remains unclear, whether there are two different points on a continuous spectrum of speech disturbances or if there exist distinct „profiles“ of dysarthria according to the proposed Richardson Syndrome (PSP-RS) with early onset of postural instability and falls, vertical gaze palsy and cognitive dysfunctions and the PSP with Parkinsonism (PSP-P) with asymmetric onset, tremor, early bradykinesia, non-axial dystonia and response to levodopa medications in the beginning. „Bogenhausener Dysarthrieskalen“ (BoDys) was used as base-line dysarthria scale: pitch pattern, loudness range, voice quality, respiration and resonance capacities, prosody and articulation were rated. Furthermore, the intelligibility is a most important index of functional impairment in dysarthria. Therefore, the „Munich Intelligibility Profile (MVP)“, a computer-based method for the assessment of the intelligibility of dysarthric patients, was used to describe the intelligibility of the patients. The PSP-P-group, at the beginning frequently confused with patients with PD, showed rigide-hypokinetic dysarthric features with hypophonia as cardinal symptom. In contrast the patients with the “classical” PSP-RS-Type show severe speech impairments in terms of a very effortful speak with a progressive loss of intelligibility. They show spastic components of dysarthria, like a very strained-strangled voice with breaks and voice stoppages, harshness and reduced pitch and loudness variability. Their loudness often is inadequate in terms of the so called “lions voice”. Further they show a hypernasality, the articulation is imprecise, the vowels are distorted. Concerning the prosody there is a very slow and strained rate of speech with equal or excess stress. The results show that the patients with PSP-RS generally suffer from severe and more progressive speech impairments beginning early after disease onset, whereas the PSP-P-group shows rather moderate symptoms. The dysarthria in PSP is subtype-specific. The hypothesis of different dysarthric profiles for the proposed clinical subtypes "Richardson Syndrome" (PSP-RS) and "PSP with parkinsonism" (PSP-P) was confirmed and based on a discriminant analysis that identified distinctive dysarthric features for both subgroups.
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Passeira, Andrea Verónica Vaz. "Stress laboral na PSP." Master's thesis, Escola Superior de Ciências Empresariais, 2011. http://hdl.handle.net/10400.26/4007.
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Dissertação de Mestrado em Segurança e Higiene no TrabalhoO presente Estudo foi aplicado a profissionais da polícia do Comando Metropolitano de Lisboa da PSP. O objectivo principal subjacente a este trabalho foi proceder à análise da problemática do stress, nos profissionais da PSP que constituem a nossa amostra. Para tal, a metodologia utilizada consistiu na aplicação de um conjunto de Questionários, designadamente, “Fontes de Stress”, “Sintomas de Stress”, “Estratégias de Coping”, “Empenho Organizacional”, “Locus de Controlo”, “Optimismo”, e por último os dados Sócio-demográficos. O Questionário “Fontes de Stress”, comporta três dimensões de análise: “Falta de Recursos”, “Problemas Organizacionais e Interpessoais” e “Stressores Policiais”. O Questionário “Sintomas de Stress” é composto, igualmente, por três dimensões de análise: “Fadiga Física”, “Esgotamento Cognitivo” e “Exaustão Emocional”. O Questionário “Estratégias de Coping” inclui duas dimensões: “Evitamento” e “Coping Activo”. O Questionário “Locus de Controlo” envolve, igualmente, duas dimensões: “Locus de Controlo Externo” e “Locus de Controlo Interno”. Os restantes Questionários, são unidimensionais. Os resultados obtidos, permitiram verificar que a dimensão das “Fonte de Stress” mais pontuada pelos inquiridos, corresponde aos “Stressores Policiais” e, ao nível dos “Sintomas de Stress”, a dimensão com mais incidência é a “Fadiga Física”. No que concerne às “Estratégias de Coping” mais utilizadas pelos polícias, estas correspondem a Estratégias de “Coping Activo”. Os resultados também demonstraram que, em termos médios, os polícias apresentam um “Empenho Organizacional” moderado, onde a maioria manifesta a predominância de um tipo de “Locus de Controlo Interno” e que se consideram Optimistas. Este estudo comportou ainda a análise das correlações entre o conjunto das subescalas, bem como a análise da influência de variáveis sócio-demográficas sobre as restantes variáveis em análise.
This study was applied to professional police officers from Lisbon's Metropolitan Police (PSP). The main objective of this study was to examine the issue of stress on the PSP professionals that constitute our sample. To this end, the methodology consisted of a set of Questionnaires, namely "Sources of Stress", "Symptoms of Stress", "Coping Strategies”, “Organizational Commitment", "Locus of Control", "Optimism" and finally the socio-demographic data. The Questionnaire "Sources of Stress” comprises three dimensions of analysis: "Lack of Resources", "Interpersonal and Organizational Issues" and "Police Stressors”. The Questionnaire "Symptoms of Stress" is composed equally of three dimensions: "Physical Fatigue", "Cognitive Exhaustion" and "Emotional Exhaustion”. The Questionnaire "Coping Strategies" includes two dimensions: "Avoidance" and "Active Coping". The Questionnaire "Locus of Control" involves also two dimensions: "External Locus of Control" and "Internal Locus of Control”. The remaining questionnaires are unidimentional. The results reflected the view that the police respondents most punctuated dimension of “Source of Stress" is “Police Stressors", and at the level of “Symptoms of Stress”, the dimension with the highest incidence is “Physical Fatigue". With regard to "Coping Strategies" used by most police departments, these strategies correspond to "Active Coping". The results also showed that on average, the police have a moderate "Organizational Commitment", where the most expresses the predominance of one type of "Internal Locus of Control" and are considered Optimistic. This study also focuses the analysis of correlations between all the subscales, as well as analysis of the influence of socio-demographic variables on other variables in the analysis.
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Tsao, Heng-Jui. "Personal Software Process (PSP) Scriber." CSUSB ScholarWorks, 2002. https://scholarworks.lib.csusb.edu/etd-project/2140.
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Personal Software Process (PSP) Scriber is a Web-based software engineering tool designed to implement an automatic system for performing PSP. The basis of this strategy is a set of tools to facilitate collection and analysis of development data. By analyzing the collected data, the developer can make informed, accurate decisions about their individual development effort.
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Gajdušek, Miroslav. "Monitor PSV a vysokofrekvenčního výkonu." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2010. http://www.nusl.cz/ntk/nusl-218619.
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This work deals with analysis methods continuous measuring systems for measurement standing wave ratio and high frequency power. Reflectometr, provision measuring standing wawe ratio, works in range frequence VHF (145 MHz, 443 MHz), for this width working frequence is used construction reflectometer with directive lead. Measurer HF power works into range 1kW. Further is in work go through problems communications bus for transmission data from unit monitor SWR a HF power into score modulus. With regard to high frequency interference is choice serial communication RS-485 , which is immune against disturbance. Further is designed evaluation unit MASTER, unit SLAVE and modules for measurement power and SWR. In finish is build up the firmware for units.
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García, Hernández Eva María. "Análisis, función y aplicaciones biotecnológicas de las proteínas del plasma seminal de porcino PSP-I y PSP-II." Doctoral thesis, Universidad de Murcia, 2007. http://hdl.handle.net/10803/10983.
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La aplicación de procesos biotecnológicos como la separación de espermatozoides X e Y mediante citometría de flujo, pueden generar la eliminación de determinados componentes del plasma seminal necesarios para conservar su funcionalidad. En este sentido, se ha observado que la adición de plasma seminal al medio espermático, protege a los espermatozoides cuando estos son sometidos a separación espermática mediante citometría de flujo. Sin embargo, diversos estudios demuestran que rel efecto beneficioso que ejerce el plasma seminal sobre los espermatozoides reside en determinadas proteínas. En el caso de la especie porcina, hay estudios previos que determinan que el efecto protector que ejerce el plasma seminal sobre los espermatozoides, se debe a una proteína denominada heterodímero PSP-I/PSP-II. El efecto beneficioso de dicha proteína sobre la funcionalidad espermática en espermatozoides de verraco altamente diluidos parece estar conservada, en su subunidad PSP-II y, concretamente, en la fracción peptídica de ésta. Estudiar, además, su localización a lo largo del tracto genital del verraco así como en las distintas fracciones del eyaculado, puede ser importante para llegar a conocer si la presencia de este heterodímero en el medio de recogida espermático de espermatozoides X e Y, es beneficioso tanto en la funcionalidad como en la capacidad fecundante de estos espermatozoides.Biotechnological procedures of semen, such as sexing using flow cytometry/cell sorting procedures, causes high dilutions during sperm manipulation, linked with the wash away or high dilution of seminal plasma components. Thus, to develop strategies to extend the viability of treated spermatozoa are necessary. It is well known that add seminal plasma (SP) to the sperm media contributes to preserving the integrity and the fertilizing potential of sperm. Nevertheless, the beneficial effects of seminal plasma seem to be restricted to specific proteins of the SP. In porcine, previous studies have related this protective effect of the seminal plasma on the sperm cells to a protein called PSP-I/PSP-II heterodimer. The beneficial effect of this protein on the functionality of highly diluted boar spermatozoa is largely preserved in its PSP-II subunit and does not appear to require its glycan moiety. Moreover, study its localization along male reproductive tract and in different portions of the ejaculate could be important to know if the presence of PSP-I/PSP-II heterodimer in the collection medium for sex sorted spermatozoa is beneficial on the in vitro function and in vivo fertilizing ability.
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Mori, Hideo, Tomohide Niimi, Masaki Yoshida, Makoto Kondo, Yusuke Oshima, and Madoka Hirako. "APPLICATION OF PSP IN LOW PRESSURE REGIME." IEEE, 2003. http://hdl.handle.net/2237/7169.
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Toussaint, Kai. "Atemmechanik unter Atmung mit PSV und PIPAP." [S.l.] : [s.n.], 2000. http://www.sub.uni-hamburg.de/disse/550/Disse.pdf.
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Caballero, Posadas Ignacio. "Estudio del plasma seminal y la espermadhesina PSP-I/PSP-II sobre la funcionalidad de los espermatozoides de verraco." Doctoral thesis, Universidad de Murcia, 2007. http://hdl.handle.net/10803/10980.
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En la siguiente tesis se obtuvieron los siguientes resultados. La adición de plasma seminal a los espermatozoides altamente diluidos ejerce un efecto beneficioso variable dependiendo de la fuente de plasma seminal. El heterodímero PSP-I/PSP-II ejerce un efecto beneficioso sobre los espermatozoides altamente diluidos mediante su adhesión al acrosoma. La incubación produce la migración del heterodímero a la región post-acrosomal, siendo eliminado de la superficie espermática. La adición del heterodímero a los medios de cocultivo entre gametos disminuye significativamente la capacidad fecundante de los espermatozoides. La preincubación de los espermatozoides de verraco tanto frescos como congelados preserva la viabilidad y motilidad espermáticas no afecta a la capacidad fecundante de los espermatozoides frescos de verraco y disminuye la capacidad fecundante de los espermatozoides congelados, la cual puede ser restaurada parcialmente mediante un lavado a través de un gradiente de Percoll.The addition of 10% of seminal plasma from certain boars maintains or enhances the viability of largely extended boar spermatozoa in vitro. The protective effect of the PSP-I/PSP-II heterodimer on highly-extended boar spermatozoa could be related to the adhesion of the heterodimer to the acrosome. Exposures of the gametes to the heterodimer during in vitro gamete co-incubation significantly decrease the sperm penetration rates and number of spermatozoa per oocytes in denuded oocytes. The effect could be mediated by exposed ZP receptors. Exposure of fresh or frozen-thawed boar spermatozoa to PSP-I/PSP-II preserves sperm viability and motility. Although there is no obvious influence of the heterodimer on the capability of fresh diluted boar spermatozoa to penetrate homologous oocytes, PSP-I/II exerts a deleterious effect when frozen-thawed spermatozoa are used to penetrate IVM-oocytes. A subsequent washing through a Percoll gradient estored sperm function in some of the cells.
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Conrad, Paul Jefferson. "Analysis of PSP-like processes for software engineering." CSUSB ScholarWorks, 2006. https://scholarworks.lib.csusb.edu/etd-project/2962.
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The purpose of this thesis is to provide the California State University, San Bernardino, Department of Computer Science with an analysis and recommended solution to improving the software development process.
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Defelicibus, Alexandre. "Koala: sistema para integração de métodos de predição e análise de estruturas de proteína." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/82/82131/tde-22062016-102823/.
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A Biologia Computacional tem desenvolvido algoritmos aplicados a problemas relevantes da Biologia. Um desses problemas é a Protein Structure Prediction (PSP). Vários métodos têm sido desenvolvidos na literatura para lidar com esse problema. Porém a reprodução de resultados e a comparação dos mesmos não têm sido uma tarefa fácil. Nesse sentido, o Critical Assessment of protein Structure Prediction (CASP), busca entre seus objetivos, realizar tais comparações. Além disso, os sistemas desenvolvidos para esse problema em geral não possuem interface amigável, não favorecendo o uso por não especialistas da computação. Buscando reduzir essas dificuldades, este trabalho propões o Koala, um sistema baseado em uma plataforma web, que integra vários métodos de predição e análises de estruturas de proteínas, possibilitando a execução de experimentos complexos com o uso de fluxos de trabalhos. Os métodos de predição disponíveis podem ser integrados para a realização de análises dos resultados, usando as métricas RMSD, GDT-TS ou TM-Score. Além disso, o método Sort by front dominance (baseado no critério de optimalidade de Pareto), proposto nesse trabalho, consegue avaliar predições sem uma estrutura de referência. Os resultados obtidos, usando proteínas alvo de artigos recentes e do CASP11, indicam que o Koala tem capacidade de realizar um conjunto relativamente grande de experimentos estruturados, beneficiando a determinação de melhores estruturas de proteínas, bem como o desenvolvimento de novas abordagens para predição e análise por meio de fluxos de trabalho.Computational Biology has developed algorithms applied to relevant problems from Biology. One of these probems is Protein Structure Prediction (PSP). Several methods have been developed on the liteture to deal with this problem. However, the reproduction of results and the comparison of the methods have not been an easy task. Accordingly, the Critical Assessment of protein Structure Prediction (CASP), has among his objectives, perform these comparisons. Besides, the developed systems for this problem have low usability, not benefiting the investigation of various methods by non experts. In order to minimize those difficulties, this project proposes Koala, a web-based system that integrates several algorithms applied to PSP and analysis, allowing the execution of complex experiments by using workflows. The prediction methods can be integrated to perform some analysis of the results, by using the RMSD, GDT-TS and TM-Score metrics. Moreover, the Sort by front dominance method (based on the criterion of Pareto optimalidad), proposed on this work, can evaluate predictions with no reference structure. The results obtained, using target proteins from recent articles and CASP11, indicate that Koala has the capability to execute a relatively large set of organized experiments, benefiting determining of better protein structures, as well as the development of new approaches for prediction and analysis through workflows.
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Abrahamsson, Robert. "Post Authorization Safety Studies (PASS) & Patient Support Programs (PSP) : Läkemedelsföretagens säkerhetsverktyg efter lansering." Thesis, Uppsala universitet, Institutionen för farmaceutisk biovetenskap, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-241995.
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Introduktion: I juli 2012 uppdaterades regelverken för farmakovigilans inom Europa och flera förändringar gjordes i de bestämmelser som rör säkerhetsstudier på godkända läkemedel. En sammanställning av dessa behövdes för att lyfta fram viktiga bestämmelser och ge en tydligare överblick av de myndighetskrav som berör PASS (Post-Authorization Safety Studies) och PSP (Patient Support Programs). Syfte: Projektet syftar till att analysera och tolka regelverk och riktlinjer gällande PASS och PSP inom Europa samt utreda vad som gäller för PASS i de skandinaviska länderna. Detta för att lyfta fram viktiga bestämmelser och underlätta tolkningen för berörda företag. Material och metoder: Huvuddelen av projektet bestod av en litteraturstudie där fokus låg på lagar och riktlinjer inom Europa. Informationsinhämtning skedde även genom intervjuer med personal på Bayer AB och Läkemedelsverket. Jämförelser har sedan gjorts mellan svenska, norska och danska regelverk. Resultat: Myndighetskraven för PASS och PSP skiljer sig åt i vissa avseenden. Etikgodkännande krävs för PASS men inte för PSP och slutrapporten från en PASS granskas av läkemedelsmyndighet medan PSP inte ger någon slutrapport. För PASS krävs i Sverige och Norge ett etikgodkännande vilket inte krävs i Danmark. I Danmark ska dokumentation om studien skickas till läkemedelsmyndigheten om Danmark är referensland eller rapportör för produkten. I Sverige och Norge krävs ingen kommunikation med läkemedelsmyndigheten. Konklusion: PASS syftar till att studera säkerheten hos läkemedel medan PSP primärt är ett stöd för patientvården i vilket vissa säkerhetsaspekter kan fångas upp sekundärt. Trots att regelverken rörande farmakovigilans gäller för samtliga EU-länder har olika tolkningar gjorts i de skandinaviska länderna och de lokala regelverken skiljer sig åt i vissa avseenden.
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Engl, Christoph. "Regulation and localisation of PSP proteins in E. coli." Thesis, Imperial College London, 2010. http://hdl.handle.net/10044/1/5603.
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The phage shock protein (Psp) response is found in many Gram-negative enterobacteria, where it helps to maintain the proton motive force (PMF) when the integrity of the inner membrane (IM) is impaired and promotes virulence of pathogens such as Yersinia or Salmonella. In Escherichia coli, Psp comprises seven genes (pspF pspABCDE and pspG) which are organised in a regulon under the control of two Sigma54-dependent promoters. Despite considerable advances, neither the mechanism of Psp induction nor the functioning of the Psp response is fully understood. Recent findings comparing the roles of ArcB in Yersinia enterocolitica and E. coli caused a dispute over the requirement of the twocomponent system ArcAB in Psp signal-transduction. The present study now establishes that ArcAB involvement is conditional and appears to be mediated via protein-protein interactions between ArcB and PspB. The study further suggests that the cellular ubiquinone pool, which acts upstream of ArcAB, may also play a role in Psp signalling whereas dissipation of proton motive force (PMF), generally inferred to be the inducing signal, is not sufficient to mount a Psp response. To gain further insight into its functioning, PspA (a negative regulator and effector of Psp) and PspG (an effector of Psp) were visualised in vivo using fusions to Green fluorescent protein (GFP). To maintain PMF, PspA was proposed to uniformly cover the cytoplasmic face of the IM. However, the present study demonstrates that PspA (and PspG) is highly organised into distinct complexes at the cell pole and the lateral cell membrane. Real-time observations revealed lateral PspA and PspG complexes are highly mobile, but absent in cells lacking MreB. Without the MreB cytoskeleton, induction of the Psp response is still observed, yet these cells fail to maintain PMF under stress conditions.
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Massey, L. A. "Clinical and radiological studies in PSP and related conditions." Thesis, University College London (University of London), 2014. http://discovery.ucl.ac.uk/1418998/.
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This thesis examines clinical and radiological aspects of Progressive Supranuclear Palsy (PSP) and related conditions. Significant milestones occur sooner in pathologically confirmed PSP than multiple system atrophy (MSA); older age of onset and shorter duration to first milestone are associated with worse prognosis in both; in PSP, the Richardson’s syndrome phenotype and male gender and in MSA, early autonomic failure and the female gender are also predictive of poorer prognosis. Using objective measurements of bradykinesia we found progressive bradykinesia and hypokinesia in Parkinson’s disease (PD) which correlates with disability and responds to levodopa but hypokinesia without decrement in PSP. Using conventional MRI 72.7% of PSP and 76.9% of MSA are correctly identified. The ‘hummingbird sign’ was highly specific for PSP, but sensitvity was 68.4%. A simple measurement of the midbrain < 9.35mm had 100% specificity for a pathological diagnosis of PSP. In a clinically diagnosed PSP 90.5% had a measurement of < 9.35mm. Using high field 9.4 Tesla MRI, the anatomy of the subthalamic nucleus is clearly defined when compared to histology in post mortem material. The anteromedial portion was hypointense in correlation with Perls stain and there was variability in the volume, shape and location of its borders. The nigrosomes within the substantia nigra were visibile as high intensity bands which correlated with calbindin poor zones on immunohistochemical stains. The volume and anatomy were preserved in PD but not PSP. Multimodal 3 Telsla MRI during life revealed distinct patterns of atrophy in PSP and MSA using voxel-based morphometry. Tract-based spatial statistics revealed abnormalities in the frontal and parieto-occipital white matter changes in PSP more than MSA. Midbrain atrophy and frontal white matter increased mean diffusivity were associated with increasing PSP rating scale score, and frontal white matter reduced fractional anisotropy with disease duration.
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Pando, Soto Brian Cesar. "PSP en la Industria del Software en Latino América." Master's thesis, Universidad Nacional Mayor de San Marcos, 2019. https://hdl.handle.net/20.500.12672/10781.
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Estudia las habilidades blandas obtenidas por los profesionales PSP y las compara con la industria mediante portales de anuncios de trabajo y encuestas, notándose como resultado la importancia de este método. Se suma una propuesta de integración a la malla curricular de una carrera de Ingeniería de Software a modo de caso. Cada persona que participa en el proceso de software debe hacerlo con procesos maduros, de manera que pueda competir en una industria que solicita calidad en sus productos, para ello el SEI propuso una metodología personal denominada PSP. En Latinoamérica existen más de 1200 profesionales certificados en esta metodología, pero el número debería ser mayor ya que según la teoría son las formas fundamentales bajo las que debería proceder un ingeniero de software en su profesión.Tesis
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Mohammad, Maruf H. "Blind Acquisition of Short Burst with Per-Survivor Processing (PSP)." Thesis, Virginia Tech, 2002. http://hdl.handle.net/10919/46193.
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This thesis investigates the use of Maximum Likelihood Sequence Estimation (MLSE) in the presence of unknown channel parameters. MLSE is a fundamental problem that is closely related to many modern research areas like Space-Time Coding, Overloaded Array Processing and Multi-User Detection. Per-Survivor Processing (PSP) is a technique for approximating MLSE for unknown channels by embedding channel estimation into the structure of the Viterbi Algorithm (VA). In the case of successful acquisition, the convergence rate of PSP is comparable to that of the pilot-aided RLS algorithm. However, the performance of PSP degrades when certain sequences are transmitted.
In this thesis, the blind acquisition characteristics of PSP are discussed. The problematic sequences for any joint ML data and channel estimator are discussed from an analytic perspective. Based on the theory of indistinguishable sequences, modifications to conventional PSP are suggested that improve its acquisition performance significantly. The effect of tree search and list-based algorithms on PSP is also discussed. Proposed improvement techniques are compared for different channels. For higher order channels, complexity issues dominate the choice of algorithms, so PSP with state reduction techniques is considered. Typical misacquisition conditions, transients, and initialization issues are reported.Master of Science
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Jurgelevič, Aliona. "Ambulatorinės pagalbos paslaugų kokybė ir prieinamumas." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2014. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2007~D_20140620_204031-40159.
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Slaugos magistro baigiamasis darbas Darbo autorė: Aliona Jurgelevič Darbo pavadinimas: Ambulatorinės pagalbos paslaugų kokybė ir prieinamumas Darbo vadovas: Doc., med. dr. Romualdas Gurevičius, VU MF VSI SMS Tyrimo tikslas: ištirti Naujosios Vilnios poliklinikos ambulatorinės pagalbos paslaugų kokybę ir prieinamumą, ypač akcentuojant į slaugos paslaugas ir jų prieinamumą iki poliklinikos reorganizacijos. Tyrimo uždaviniai: Išnagrinėti pagrindinius N. Vilnios poliklinikos veiklos našumo rodiklius dinamikoje (nuo 2000 m. iki 2004 m.); Įvertinti N. Vilnios poliklinikos paslaugų prieinamumą; Įvertinti ambulatorinės pagalbos kokybę; Nustatyti N. Vilnios poliklinikos klientų lūkesčius. Tyrimo objektas ir metodika: Pirminės sveikatos priežiūros paslaugų kokybė, pacientų lūkesčiai bei poliklinikos našumo rodiklių kitimas. Tyrimas buvo atliktas N. Vilnios poliklinikoje, kur atsitiktine atranka buvo apklausti 488 nuo 18 metų ir vyresni moteriškos ir vyriškos lyties respondentai, iš jų 476 (97,5%) apklaustieji buvo įtraukti į tyrimą. Apklausai naudojome sukurtą iš dviejų šaltinių bei mūsų papildytą klausimyną, kurį sudarė 44 klausimai. Naujosios Vilnios poliklinikos veiklos našumo rodikliams įvertinti naudojome Harvard Graphics 4.0 paketą bei anketos duomenų analizei naudojome statistinio apdorojimo programą SPSS 11v., skirtumą tarp grupių statistiškai patikimu laikėme, kai P<0,05. Darbo rezultatai: Vertinant poliklinikos veiklos našumo rodiklius... [toliau žr. visą tekstą]Master’s thesis in Nursing Author of the work: Aliona Jurgelevic Title of the work: Quality of Care and Accessibility of Ambulatory Health Service Research Adviser: Doc., med. Dr. R. Gurevicius, VUMF IPH DSM The objective of the research: to research quality and accessibility of out-patient services rendered in N.Vilnia Polyclinics, by emphasizing nursing services and their accessibility prior to reorganization of the polyclinics. Tasks of the research: To analyze main efficiency indices of N.Vilnia Polyclinic’s activity from 2000 to 2004; To evaluate accessibility of services rendered by N.Vilnia Polyclinics; To assess quality of out-patient services; To determine expectations of N.Vilnia Polyclinic’s clients. The subject and methodology of the research: quality of primary health care services, expectations of clients and change of the Polyclinic’s efficiency indices. The research was carried out at N.Vilnia Polyclinics. 488 respondents, both men and women over 18 year old were surveyed, 476(97,5%) of which were involved in the research. The survey was performed with the help of our supplemented questionnaire, made of two sources and comprising 44 questions. The efficiency indices of N.Vilnia Polyclinic’s activity were assessed using Harvard Graphics 4.0 package. Data of the questionnaire were analyzed with statistical processing program SPSS 11v. and difference among groups was considered reliable, where P<0,05. Results of the research: In the course of assessment of... [to full text]
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Houston, Elizabeth Margaret. "A critical investigation of the Primary Schools Nutrition Programme (PSNP) in the Eastern Cape." Thesis, Rhodes University, 1997. http://hdl.handle.net/10962/d1002993.
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The thesis focuses on the Primary School Nutrition Programme (PSNP), particularly in the Eastern Cape, as a government nutrition and education project, and its failure to achieve its stated goals. The programme experienced problems almost as soon as it was introduced. The press reported incidents of fraud and maladministration and the programme was halted and restarted numerous times. The thesis seeks to offer some insight as to why the government was unable to reach its stated objectives in the implementation phase of the programme. State theory informs the thesis in an attempt to further explain why governments often seem unable to attain their intended goals. The thesis provides an alternative to government development programmes, arguing that NGOs are better equipped to deal with the particular problems that people on the ground experience when dealing with issues like nutritional vulnerability. Operation Hunger provides an excellent case study for how development of this nature ought to occur. The essential argument of the thesis is that there is an inherent tension between what a government's stated intentions is and what, it, in reality, intends to gain from such programmes. It is the contention of this thesis that the Government of National Unity embarked on the PSNP, not to ensure nutritional development for its own sake, but rather to curry favour with its constituents. Operation Hunger, and other organisations like it, provide relief to vulnerable communities with no hidden agenda in mind. Their mandate is solely that they provide assistance. The thesis argues, then, that NGOs have a role in domestic and international politics, that they can make up for or do better, or at least well, things that governments struggle to do.
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Zhou, Li. "Low Complexity PSP-MLSE receiver for H-CPM with receive diversity." Thesis, University of Canterbury. Department of Electrical and Computer Engineering, 2009. http://hdl.handle.net/10092/4455.
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This thesis is a study of harmonized continuous phase modulation (H-CPM)
coupled with receive diversity as applied to mobile radio communication applications.
H-CPM is the modulation technique specified by the American Public Safety
Communication Official Project 25 (APCO P25) Phase 2 standards, which is focused on public safety applications. Practical implementation of an H-CPM maximum likelihood sequence estimator (MLSE) receiver requires complex reduction techniques to ensure a cost effective form. In addition, it must be able to handle a fast fading environment, which is often encountered in public safety applications. Here, the reduction of receiver complexity and the combating of fast fading situations are
investigated via MATLAB simulation.
By using tilted phase and frequency pulse truncation techniques, the
complexity of an H-CPM MLSE receiver is successfully reduced. In particular, the original 384-state receiver is first reduced to a 192-state receiver through the use of
tilted phase. Then it is further reduced to 48-states and finally to 12-states by applying frequency pulse truncation. Simulation, assuming static channels, shows that the bit
error rate (BER) performance of a 12-state receiver is essentially identical to that of a 384-state receiver, despite a 97% reduction in computational complexity.
To take into account the effects of fading, channel gain estimation via persurvivor processing (PSP) is incorporated into the reduced complexity MLSE receiver. Using a weighted-sum approach to the PSP gain estimates, it was found that
at Doppler shifts of 5 Hz, 40 Hz and 80 Hz, the receiver performance was comparable to that obtainable by rival techniques. To further reduce the effect of fading, receive diversity combining was investigated, where a three-antenna diversity scheme
is applied to the reduced state PSP-based MLSE receiver. Three different combining techniques, namely selective combining (SC), equal gain combining (EGC) and maximum ratio combining (MRC) were compared. It was found via simulation that the best performance is achieved using MRC, with as much as 14dB improvement achieved by applying triple diversity MRC.
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Moura, Rui Filipe Resende Melo Coelho de. "A inteligência emocional no comando e liderança das esquadras da PSP." Master's thesis, Universidade de Aveiro, 2011. http://hdl.handle.net/10773/7603.
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Mestrado em Administração e Gestão PúblicaO presente trabalho propõe-se medir a Inteligência Emocional nos Comandantes de Esquadra e procura construir um quadro inicial de referência para posteriores estudos sobre a Inteligência Emocional na Polícia de Segurança Pública, procurando provocar a reflexão e a intervenção institucional no sentido do desenvolvimento das capacidades emocionais dos Comandantes de Esquadra.
This work pretends to measure the Emotional Intelligence of the Police Station Commanders, and to build a referential kick-off board to future studies about Emotional Intelligence at Polícia de Segurança Pública, trying to provoke reflections and organizational interventions to develop the emotional capabilities of the Police Station Commanders.
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GAUDON, CLAUDINE. "Identification de proteines interagissant avec les recepteurs nucleaires caracterisation d'un potentiel coactivateur de levure, psv1." Université Louis Pasteur (Strasbourg) (1971-2008), 1997. http://www.theses.fr/1997STR13185.
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Les recepteurs nucleaires appartiennent a une superfamille de facteurs de transcription dont l'activite est, pour la plupart, controlee par un ligand. Ils jouent un role important au cours de l'embryogenese, dans les mecanismes de croissance et de differenciation cellulaire. On sait aujourd'hui que ces recepteurs presentent une structure modulaire organisee en domaines fonctionnels : la region a/b contient une fonction de transactivation af-1 constitutive, la region c correspond au domaine de liaison a l'adn, la region d sert de charniere avec la region e qui contient le domaine de liaison du ligand et une fonction de transactivation dependante du ligand appelee af-2. Afin de determiner les mecanismes qui controlent et gouvernent l'activite transcriptionnelle des recepteurs nucleaires, mon travail de these a consiste a identifier des proteines capables d'interagir avec ces recepteurs. L'approche choisie est celle du criblage de banques d'expression par la technique du double hybride. Un premier criblage a consiste a utiliser la region cd de rar comme appat et a cribler une banque d'adnc d'embryons de souris. Ce criblage a conduit a l'isolement d'un membre de la famille des recepteurs nucleaires ppar. Un deuxieme criblage avec la region def de rar, visant a identifier des proteines de levure capables d'interagir avec les recepteurs nucleaires, a conduit a l'isolement de plusieurs proteines dont l'une d'entre elles, psu1, possede les proprietes attendues pour un coactivateur de la fonction af-2 des recepteurs nucleaires : 1) psu1 interagit avec le domaine de(f) des recepteurs nucleaires en presence de ligand. 2) l'integrite du domaine d'activation af-2ad core est necessaire a l'interaction. 3) une diminution du pool endogene de psu1 conduit a une baisse d'activite de la fonction af-2 du recepteur des oestrogenes. 4) psu1 est capable d'activer la transcription lorsqu'il est fusionne a un domaine de liaison a l'adn heterologue. Sur la base de ces resultats, psu1 semble jouer un role dans l'activation des recepteurs nucleaires dans la levure.
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Ahadi, Mohammad Reza. "Development of an alternative test procedure to 'BS 812' for accelerated polishing of roadstones." Thesis, Queen Mary, University of London, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.324632.
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de, Sá Braga Oliveira André. "Efeitos da ventilação mecânica controlada e da ventilação por pressão de suporte sobre o músculo diafragma de ratos." Universidade Federal de Pernambuco, 2010. https://repositorio.ufpe.br/handle/123456789/8147.
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Previous issue date: 2010A assistência ventilatória mecânica (AVM) controlada induz profundas alterações na musculatura diafragmática, causando a chamada disfunção diafragmática induzida pela ventilação mecânica (DDIV). Essas alterações parecem poder ser atenuadas quando utilizados modos com participação da atividade diafragmática, como o de Pressão de Suporte (PSV). O objetivo do trabalho foi avaliar os efeitos do modo ventilatório controlado por pressão controlada (PCV-C) e do modo PSV sobre a histologia e morfometria do músculo diafragma de ratos. Ratos (n = 18) da linhagem Wistar foram incluídos nesse estudo prospectivo. Após injeção intraperitoneal de anestésico e sedativo, os ratos foram distribuídos no grupo controle (RE) e para receber AVM por 6 horas no modo PCV-C e no modo PSV. Após esse período, os animais foram eutanasiados, o diafragma retirado e encaminhado para a análise histológica e morfométrica. Os resultados revelaram uma redução da área das fibras musculares de 15% no grupo PCV-C em comparação ao controle (p<0,001) e de 10% quando comparado ao grupo PSV (p<0,05). Já com relação ao diâmetro menor das fibras musculares observou-se uma redução de 9% do grupo PCV-C em comparação ao controle (p<0,001) e de 6% em relação ao grupo PSV (p<0,05). Quando avaliada a área dos mionúcleos, notou-se uma redução de 16% desse parâmetro no grupo PCV-C, comparado ao PSV (p<0,05). Não houve diferença significativa no perímetro dos mionúcleos entre os grupos estudados (p>0,05). O grupo PCV-C apresentou atrofia muscular em um período curto de ventilação mecânica. O modo PSV parece atenuar os efeitos da DDIV, sendo uma alternativa eficiente no controle da atrofia muscular decorrente do uso do suporte ventilatório
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Nguyen, Amy U. Mauriello Sally M. "A comparison of technique errors between film and photostimulable-phosphor (PSP) receptors." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2006. http://dc.lib.unc.edu/u?/etd,279.
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Thesis (M.S.)--University of North Carolina at Chapel Hill, 2006.Title from electronic title page (viewed Oct. 10, 2007). "... in partial fulfillment of the requirements for the degree of Master of Science in the Curriculum of Dental Hygiene Education in the School of Dentistry." Discipline: Dental Hygiene Education; Department/School: Dentistry.
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Dideban, Daryoosh. "Statistical modelling of nano CMOS transistors with surface potential compact model PSP." Thesis, University of Glasgow, 2012. http://theses.gla.ac.uk/3257/.
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The development of a statistical compact model strategy for nano-scale CMOS transistors is presented in this thesis. Statistical variability which arises from the discreteness of charge and granularity of matter plays an important role in scaling of nano CMOS transistors especially in sub 50nm technology nodes. In order to achieve reasonable performance and yield in contemporary CMOS designs, the statistical variability that affects the circuit/system performance and yield must be accurately represented by the industry standard compact models. As a starting point, predictive 3D simulation of an ensemble of 1000 microscopically different 35nm gate length transistors is carried out to characterize the impact of statistical variability on the device characteristics. PSP, an advanced surface potential compact model that is selected as the next generation industry standard compact model, is targeted in this study. There are two challenges in development of a statistical compact model strategy. The first challenge is related to the selection of a small subset of statistical compact model parameters from the large number of compact model parameters. We propose a strategy to select 7 parameters from PSP to capture the impact of statistical variability on current-voltage characteristics. These 7 parameters are used in statistical parameter extraction with an average RMS error of less than 2.5% crossing the whole operation region of the simulated transistors. Moreover, the accuracy of statistical compact model extraction strategy in reproducing the MOSFET electrical figures of merit is studied in detail. The results of the statistical compact model extraction are used for statistical circuit simulation of a CMOS inverter under different input-output conditions and different number of statistical parameters. The second challenge in the development of statistical compact model strategy is associated with statistical generation of parameters preserving the distribution and correlation of the directly extracted parameters. By using advanced statistical methods such as principal component analysis and nonlinear power method, the accuracy of parameter generation is evaluated and compared to directly extracted parameter sets. Finally, an extension of the PSP statistical compact model strategy to different channel width/length devices is presented. The statistical trends of parameters and figures of merit versus channel width/length are characterized.
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Guetta, Brigitte. "Vieillissement hygrométrique des composites à matrice PSP étude cinétique, mécanique et spectroscopique /." Grenoble 2 : ANRT, 1987. http://catalogue.bnf.fr/ark:/12148/cb376056336.
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Santos, Susana Maria da Silva Ferreira Matias dos. "Suicídio nas forças policiais: um estudo comparativo na PSP, GNR e PJ." Dissertação, Instituto de Ciências Biomédicas Abel Salazar, 2006. http://hdl.handle.net/10216/7151.
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Guetta, Brigitte. "Vieillissement hygrothermique de composites a matrice psp : etude cinetique, mecanique et spectroscopique." Paris, ENMP, 1987. http://www.theses.fr/1987ENMP0057.
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Kumar, Pradeep. "Development of a Single-shot Lifetime PSP Measurement Technique for Rotating Surfaces." The Ohio State University, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=osu1285044595.
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Nunes, Cristina Isabel dos Santos Monteiro. "As redes sociais na imagem da marca PSP (Polícia de Segurança Pública)." Master's thesis, Instituto Superior de Economia e Gestão, 2019. http://hdl.handle.net/10400.5/19781.
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Mestrado em MarketingAs redes sociais são ferramentas online de social media que nos fazem partilhar conversas e experiências com pessoas e culturas sem limitações geográficas. Caso haja uma boa conceção de conteúdo, gestão das contas e interação com o público, estas podem afetar positivamente a imagem de uma organização. No entanto a fácil, barata e rápida comunicação nestes meios acarreta mais exposição da marca ao risco de destruição de reputação. O objetivo deste estudo é compreender de que forma a presença nas redes sociais influencia a imagem da organização governamental Polícia de Segurança Pública (PSP). Assim, foi observada a interação da PSP com a sociedade nas diferentes redes sociais em que está presente, bem como relatórios internos; foram realizadas duas entrevistas semiestruturadas para se perceber a imagem desejada; e foi ainda desenvolvido um estudo quantitativo, com uma amostra por conveniência, através de um questionário online, obtendo-se o total de 486 respostas, sendo 403 destas consideradas estatisticamente válidas. Este tem com principal objetivo medir a imagem da PSP utilizando como instrumento a escala adaptada "Personalidade da Marca" sugerida por Aaker (1997). Percebeu-se que as redes sociais influenciam, de facto, a imagem da PSP uma vez que os seus seguidores têm uma imagem e perceções bastante mais positivas do que os não seguidores. Por outro lado, confirmou-se que essa imagem que os seguidores têm está alinhada e em sintonia com a imagem desejada pela organização, mas ainda há muito trabalho para fazer.
Social media are online tools that make us share conversations and experiences between different people and cultures without geographical limitations. Good content design, account management and audience interaction can positively affect an organization's image. However easy, inexpensive and fast communication in these media entails more exposure of the brand, increasing the risk of damaging reputation. The goal of this study is to understand how the presence in social media influences the image (reputation component) of a portuguese governmental organization, such as Polícia de Segurança Pública (PSP). Therefore, was analyzed the PSP interaction with society throughout different social media as well as the internal reports; two semi-structured interviews to perceive what is the desired image they want to be seen as; likewise a quantitative study was conducted with a convenience sample through an online questionnaire, resulting in 486 total responses of which 403 were considered statically valid. The instrument used was the adapted Brand Personality suggested by Aaker (1997) and its purpose is to measure the PSP image. It is possible to analyze that social medial do, in fact, influence the PSP image since its followers have a much more positive image and perceptions that non-followers. On the other hand, it has been confirmed that this image that the followers have is aligned with the image that the organization desired to be, yet there is still room for improvement.
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Santos, Susana Maria da Silva Ferreira Matias dos. "Suicídio nas forças policiais: um estudo comparativo na PSP, GNR e PJ." Master's thesis, Instituto de Ciências Biomédicas Abel Salazar, 2006. http://hdl.handle.net/10216/7151.
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Pongrácz, E. (Eva). "Re-defining the concepts of waste and waste management:evolving the Theory of Waste Management." Doctoral thesis, University of Oulu, 2002. http://urn.fi/urn:isbn:9514268210.
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Abstract
In an attempt to construct a new agenda for waste management, this
thesis explores the importance of the definition of waste and its impact
on waste management, and the role of ownership in waste management. It is
recognised that present legal waste definitions are ambiguous and do not
really give an insight into the concept of waste. Moreover, despite its
explicit wish of waste prevention, when according to present legislation a
thing is assigned the label of a waste, it is going to be treated like
waste, implicitly legislation thus amasses waste. The philosophical
ramifications inherent in such definitions mean that they are not capable
of constructing a system that, by its very nature, results in a
sustainable waste management system. It is also a fact that, while there
are numerous practices as to how to deal with a particular type of waste,
there is no theory of waste management. In this thesis, waste as a concept
is analysed from the point of view of why and when waste is created. Using
the PSSP language, waste is classified based on the Purpose and
Performance attributes. New, dynamic definitions for waste and waste
management are offered, which explain why waste is created and
intrinsically offer a solution to how the problem could be solved.
Additional waste-related concepts are introduced, which are thought to
have great potential for improvement on waste regulation. The concept of
ownership is explained as rights and responsibilities of waste
creators/owners: it is thus crucial to raising awareness about waste.
Ownership in itself often dictates which waste management options are
preferentially adopted by a given community. The role of legislation in
producing monitoring systems for the transfer of ownership as well as
abandonment of ownership is analysed. To avoid obstacles to resource
conservation due to materials being considered waste, a definition for
non-waste is introduced. The new agenda for waste management thus focuses
upon the development of more appropriate, sustainable definitions so that
what is now commonly perceived as being waste will in fact be increasingly
seen as resource-rich, 'non-waste'. The role of waste management is
explained as control of all waste-related activities, with the aim of
preventing, minimising or utilising waste. The need for a theory of waste
management is explained, and the first building blocks of the theory are
proposed. This thesis is offered as the first step toward scientification
of waste management.
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Tueros, Farfán Felipe Gonzalo. "Desarrollo de un Circuito Genético Sintético Conformado por el Gen de la Proteína Verde Fluorescente (GFP) y el Promotor psp de Escherichia coli." Bachelor's thesis, Universidad Ricardo Palma, 2015. http://cybertesis.urp.edu.pe/handle/urp/838.
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El aumento de la actividad minera en el Perú hace necesario el desarrollo de tecnologías rápidas y económicas de detección de contaminantes para su monitoreo y control. Implementando conocimientos de biología molecular y de la regulación génica podemos construir un circuito genético sintético que posibilite el monitoreo de sustancia toxicas que generen estrés oxidativo como son los compuestos cianurados. El objetivo de esta investigación es desarrollar un circuito genético sintético conformado por el promotor de la proteína del shock por fagos (psp) de Escherichia coli y las secuencia codificante del gen de la proteína verde fluorescente (GFP). La construcción de dicho circuito se logró usando estrategias de clonamiento por topoisomerasas y clonamiento clásico con enzimas de restricción, se usó la reacción en cadena de la polimerasa (PCR) para confirmar que todos los segmentos del circuito estén presentes en el vector. Los estudios preliminares de la actividad del nuevo circuito se realizaron transformando genéticamente células competentes de E. coli. La observación de dichas bacterias muestra una expresión de GFP continua, lo que indica que el circuito sintético está siendo activado sin estar en presencia de agentes de estrés oxidativo, lo que suponía una posible interacción con otros sistemas de regulación de estrés en la célula. Due to the increase of mining activity in Peru new technologies that can detect and monitor hazardous pollutants in a faster and cheaper way must be developed. Implementing molecular biology knowledge about genetic regulation we are able to construct a synthetic genetic circuit that can allow the monitoring of toxic substances that generate oxidative stress such us cyanide compounds. The objective of this research is to develop a synthetic genetic circuit from the promoter of the phage shock protein operon from E. coli and the complementary DNA of the green fluorescent gene (GFP). The construction of the circuit was achieved using classic cloning strategies with restriction enzymes and also more advanced strategies such us topoisomerase cloning, the polymerase chain reaction (PCR) was used to confirm the presence of all the desire segments in the vector. Preliminary studies of the circuit activity were carried out by genetically transforming competent E. coli cells. The observation of the bacteria shows a continuous expression of GFP without any inducer, this indicates that the synthetic circuit is being activated through a possible interaction with other stress response pathway.
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Liu, Quan. "STUDY OF HEAT TRANSFER CHARACTERISTICS OF IMPINGING AIR JET USING PRESSURE ANDN TEMPERATURE SENSITIVE LUMINESCENT PAINT." Doctoral diss., University of Central Florida, 2006. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/2261.
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Luminescent coating measurement system is a relatively new technology for quantitative pressure and temperature measurement. Usually referred to as Pressure Sensitive Paint (PSP) and Temperature Sensitive Paint (TSP), luminescent coatings contain sensor molecules, which undergoes a luminescent transition when excited with light of proper wavelength. The reaction is pressure and/or temperature sensitive. The image of TSP or PSP coated model surface can be captured with a scientific grade camera and then processed to obtain full field temperature and pressure distribution with very high fidelity. The preparation time of the technique is short. The measurement system offers an economic alternative to conventional testing methods using large number of pressure taps and thermocouples. The purpose of the experiment in this thesis is to take the benefits of the TSP and PSP technique, develop a well-controlled process and then apply the technique for a fundamental study on jet impingement heat transfer. First, Uni-Coat TSP and Binary-FIB PSP purchased from ISSI Inc. are calibrated to high accuracy. The calibration uncertainty of TSP and PSP are found to be ±0.93 °C and ±0.12 psi over temperature and pressure ranges of 22 to 90 ° C and 5 to 14.7 psia, respectively. The photodegradation of TSP is then investigated with the same calibration system. The photodegradation refers to the phenomenon of decreasing emission intensity as the luminescent paint is exposed to the illumination light during testing. It was found that photodegradation rate is a strong function of temperature and the optical power of illumination lighting. The correlation developed in this work is expected to compensate the degradation of TSP to achieve high measurement accuracy. Both TSP and PSP were then applied in the flow and heat transfer measurement of single round impinging air jet. Various separation distance (Z/D) and jet Reynolds number are tested. Pressure measurement on the jet impinged target surface using PSP clearly shows the boundary of jet impingement zone, which broadens with separation distance. In heat transfer experiment using TSP, the "second peak" in local heat transfer occurring at radial distance r/D around 2 is clearly observed when the separation distance Z/D is shorter than the length of jet potential core. The slight variation in radial location and the amplitude of the "second peak" are captured as Z/D and jet Reynolds number change. The optimum Z/D of stagnation point heat transfer is found to be around 5. The effect of jet nozzle configuration is investigated. It is found that the heat transfer rate associated with "tube jet" is generally higher than that of "plate jet". The difference in heat transfer between the two jet configurations is related to the weaker entrainment effect associated with "plate jet", where the entrainment of surrounding air is confined by the injection plate, especially under small Z/D circumstances. When compared with the benchmark data in the literature, the averaged heat transfer data of "tube jet" matches the empirical data better than those of "plate jet". The maximum difference is 3.3% for tube jet versus 15.4% for plate jet at Reynolds number of 60000 and Z/D of 5. The effect of surface roughness on jet impingement heat transfer is also studied. Heat transfer can be significantly increased by the enhanced roughness of the target surface. The largest roughness effect is achieved near stagnation point at high jet Reynolds number. Compared to the heat transfer to a smooth plate, as high as 30.9% increase in area-averaged Nusselt number is observed over a rough surface at r/D=1.5 and jet Reynolds number of 60000. The most significant advance of the present work is that both temperature and pressure measurement be obtained with the same measurement system and with accuracy comparable to traditional testing methods. The procedures that were employed in this work should be easy to apply in any university or industrial testing facility. It provides a rapid testing tool that can help solve complex problems in aerodynamics and heat transferPh.D.
Department of Mechanical, Materials and Aerospace Engineering;
Engineering and Computer Science
Mechanical Engineering
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Deutschenbaur, Lorenz. "Bildgebende und neurophysiologische Untersuchungen zur Lokomotion bei PSP-Patienten und Anwendungsbeobachtung von Rasagilin." Diss., lmu, 2012. http://nbn-resolving.de/urn:nbn:de:bvb:19-138701.
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Dohmann, Helena [Verfasser], and Veit [Akademischer Betreuer] Mylius. "Schmerzwahrnehmung und Schmerzempfindung bei Progressiver Supranukleärer Blickparese (PSP) / Helena Dohmann. Betreuer: Veit Mylius." Marburg : Philipps-Universität Marburg, 2013. http://d-nb.info/1032314761/34.
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Vásquez, Cristian Andrés Morales. "A methodology to select the electric propulsion system for Platform Supply Vessels (PSV)." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/3/3135/tde-26122014-164655/.
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The present work proposes a methodology to define the electric propulsion system for PSVs. This methodology was applied to a case study: the conceptual design of a PSV for operation at the pre-salt fields at Santos basin. First, four different alternatives of electric propulsion systems for the PSV are presented and sized. The first one has induction motors as main propulsion motors, the second one has synchronous motors as main propulsion motors; the third and fourth alternatives are the same as the first and second, respectively, with a batteries bank connected to the main switchboard. Each of the four arrangements was contemplated with two options for Diesel generators: high speed and medium speed generator sets. The mass, volume, fuel consumption, exhaust gases emissions and reference capital costs for each arrangement are estimated and analyzed. Moreover, an economic analysis through the Net Present Value (NPV) is performed. The methodology ends with the Analytic Hierarchy Process (AHP) to support the decision making procedure. Some of the parameters obtained for each arrangement (mass, volume, fuel consumption, exhaust gases and NPV) are used as criteria and sub-criteria for selection. Two scenarios are evaluated, the first scenario gives more importance to the financial component of the design; the second scenario sets the exhaust gases emissions as the more significant parameter. The results were different, the arrangements 1 and 2 with medium speed Diesel generator sets appear as the most suitable option from the economical point of view; whereas the arrangements with batteries and high speed Diesel gensets are the best options to reduce the exhaust emissions.O presente trabalho propôs uma metodologia para definir o sistema de propulsão elétrica para PSVs. A metodologia foi aplicada para um caso estudo: o projeto conceitual de um PSV para operar nos campos do pré-sal na Bacia de Santos. Primeiramente, as quatro diferentes alternativas de sistemas de propulsão elétrica para PSV são apresentadas e dimensionadas. A primeira alternativa tem motores de indução como motores de propulsão principal, a segunda alternativa tem motores síncronos como motores de propulsão principal; a terceira e quarta alternativas são as mesmas que a primeira e a segunda, respectivamente, com um banco de baterias conectado ao quadro principal. Cada um dos quatro arranjos foi considerado com duas opções para Diesel geradores: Diesel geradores de alta e média rotação. A massa, volumem, consumo de combustível, emissão de gases e os custos capitais de referência para cada arranjo são estimados e analisados. Adicionalmente, uma análise económica usando o Valor Presente Líquido (VPL) é feita. A metodologia finaliza com o Analytic Hierarchy Process (AHP) para apoiar o processo de escolha de alternativa. Alguns dos parâmetros obtidos para cada arranjo (massa, volumem, consumo de combustível, gases poluentes e o VPL) são utilizados como critérios de seleção. Dois cenários são avaliados, o primeiro cenário dá maior importância à parte financeira do projeto, o segundo cenário estabelece as emissões de gases poluentes como o parâmetro mais significativo. Os resultados foram diferentes, os arranjos 1 e 2 com Diesel geradores de média rotação se apresentam como a opção mais adequada desde o ponto de vista econômico; enquanto os arranjos com baterias e Diesel geradores de alta rotação são a melhor opção para reduzir as emissões de gases poluentes.
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Paula, Danielle Bezerra de. "A constru??o de posicionamento valorativo no cronotopo do PSV- 2008 da UFRN." Universidade Federal do Rio Grande do Norte, 2011. http://repositorio.ufrn.br:8080/jspui/handle/123456789/16213.
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Previous issue date: 2011-06-09Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior
Situ?e dans le domaine de la Linguistique Appliqu?e (CELANI, 1998; MOITA LOPES, 2004, 2006, 2009), cette recherche documentaire fait partie d‟une approche qualitative-interpr?tative qui privil?gie une perspective socio-historique (FREITAS, 2002, 2007; ROJO, 2006). Le but principal de ce travail est d‟analyser comment l‟interlocution a lieu dans les lettres argumentatives produites par 10 sujets-?nonciateurs ayant particip? au processus de s?lection du ?vestibular? d‟UFRN, appel? ici le chronotope du PSV-2008. Pour cela, les objectifs sp?cifiques qui guident cette recherche consistent ? analyser les modes d‟assimilation du discours de l‟autre par le candidat, ? identifier les positions axiologiques r?sultant des formes du processus interlocutif, et ? construire une vision du sujet-?nonciateur sur la base des choix de valeurs de l‟?nonciateur et des relations espace-temps qui constituent l‟?nonciateur et l‟interlocuteur. Quant ? la th?orie, la recherche est fond?e principalement sur la notion de chronotope de Bakhtin une cat?gorie qui d?coule de la th?orie du roman et probl?matis?e par Amorim (2004) en articulation avec les r?flexions th?oriques de Geraldi (1997, 1999, 2006), Britto (2006) et Antunes (2005, 2006) sur le processus d‟?criture les relations dialogiques, la responsivit? et les voix sociales (BAKHTIN, 1990, 2003, 2008; BAKHTIN/VOLOCHINOV, 2006) qui sont travers?es par la conception dialogique du langage. L‟analyse nous a permis d‟identifier, principalement, deux d?bats dialogiques, dont le premier confronte le candidat ? la dissertation et le second, ? des interlocuteurs mentionn?s dans la proposition. Les sujets ont formul? leurs ?nonc?s sur un ton d‟indignation, en critiquant ce que l‟interlocuteur avait exprim?. Les candidats ont fait appel ? la formation d‟un sc?nario d‟espoir, de cr?dulit?, de respect et d‟?thique, conforme ? la dignit? de l‟?tre humain. Ces r?sultats mettent en ?vidence la fa?on dont des sujets multiples et h?t?rog?nes, ins?r?s dans la dimension de la vie, prennent position ? l‟int?rieur des pratiques discursives, face aux coordonn?es d‟espace et de temps
Situada na Lingu?stica Aplicada (CELANI, 1998; MOITA LOPES, 2004, 2006, 2009), esta pesquisa documental se inscreve em uma abordagem qualitativo-interpretativista de perspectiva s?cio-hist?rica (FREITAS, 2002, 2007; ROJO, 2006). O objetivo geral consiste em analisar como ocorre a interlocu??o nas cartas argumentativas produzidas por 10 sujeitos-enunciadores que participaram do Processo Seletivo Vestibular de 2008 da UFRN, aqui denominado cronotopo do PSV-2008. Para isso, os objetivos espec?ficos que orientam esta pesquisa s?o: analisar os modos de assimila??o do discurso alheio ao dizer do vestibulando; identificar posicionamentos axiol?gicos decorrentes das formas do processo interlocutivo observadas; e construir uma vis?o de sujeito-enunciador com base nas escolhas valorativas do enunciador e no tempo-espa?o que constituem as rela??es entre enunciador e interlocutor. Quanto ao aporte te?rico, a investiga??o se fundamenta, principalmente, nas no??es bakhtinianas de cronotopo categoria advinda da teoria do romance e problematizada por Amorim (2004) em articula??o com as reflex?es te?ricas de Geraldi (1997, 1999, 2006), Britto (2006) e Antunes (2005, 2006) sobre o processo de escrita , rela??es dial?gicas, responsividade e vozes sociais (BAKHTIN, 1990, 2003, 2008; BAKHTIN/VOLOCHINOV, 2006) as quais s?o atravessadas pela concep??o dial?gica da linguagem. Pela an?lise, identificamos, principalmente, dois debates dial?gicos, um travado com a prova de reda??o, outro com um dos interlocutores apontados na proposta. Os sujeitos carregaram seus enunciados de um tom de indigna??o, criticando o que expressou o interlocutor. Os vestibulandos recorreram ? forma??o de um cen?rio de esperan?a, credulidade, respeito, ?tica, natureza digna do ser humano. Essas constata??es permitem vislumbrar como sujeitos m?ltiplos e heterog?neos, inseridos no mundo da vida, tomam posi??o nas pr?ticas discursivas face ?s coordenadas temporais e espaciais
38
Niimi, Tomohide, Hideo Mori, Kazuki Okabe, Yusuke Masai, and Mashio Taniguchi. "ANALYSES OF FLOW FIELD STRUCTURES AROUND LINEAR-TYPE AEROSPIKE NOZZLES USING LIF AND PSP." IEEE, 2003. http://hdl.handle.net/2237/7168.
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Heidrich, Eyleen Sabine [Verfasser]. "Aktivierung des Psp-Systems durch TatA-induzierten Membranstress in Escherichia coli / Eyleen Sabine Heidrich." Hannover : Gottfried Wilhelm Leibniz Universität Hannover, 2019. http://d-nb.info/1204458421/34.
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Yang, Xiaotong, and 楊曉彤. "The anticancer mechanisms of polysaccharide peptide (PSP) derived fromthe Chinese medicinal fungus coriolus versicolor." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2004. http://hub.hku.hk/bib/B31246229.
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Chen, Pu, and 陳璞. "Variants of the SVD model - WSVD and PSVD." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/6duy67.
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碩士國立中央大學
軟體工程研究所
106
With the development of the Internet, people are faced with more and more choices, such as the choice of products in shopping websites and the choice of which videos to watch in video and audio websites. The recommendation system plays an important role in these sites to help people decide quickly. In this paper, we analyze the well known method -- the latent factor model in the recommendation system, and propose the weighted latent factor model and the polynomial latent factor model. These two models respectively give the traditional latent factor model weights and nonlinear feature combinations. We conducted many experiments on these two models for the five open data sets and found that the two models have better predictive effects than the traditional models. Since our proposed model is based on the latent factor models, our model can also be applied to other latent factor models such as SVD++ model and NMF model.
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Lin, Wei-Chih, and 林威志. "VLSI Implementation of FPIC Design for PSiP/PSoC." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/46845685191940017745.
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碩士國立臺灣海洋大學
資訊工程學系
105
Field Programmable Gate Array (FPGA) is composed by logic block, routing resource, and I/O. Routing resource occupy 70% area of a FPGA, so we can say that routing architecture dominates the routing efficiency and area. Routing architecture is composed by metal wires and programmable switches. Intuitively, increasing programmable switches deliver good routability in a FPGA. On the contrary, because programmable switches have high resistance and capacities, too many programmable switches would cause the area increasing as well as the operating speed slow. So, Yen et al. propose a routing structure called polygonal switch network (PSN), and the structure has high routibility and few switches. Polygonal switch network PSN(4s, m , n) is composed by the connections of a polygonal switch block SB(4s, m) and 2s connection block CB(m, n). PSN can be applied on FPIC (Field Programmable Interconnection Chip) which is made by routing structures. In terms of switch numbers, Yen et al. has proved that using PSN(4s, m, s), s>1, structure is more efffeicient that using traditional 4-side switch network (s=1). PSN(4s, m, n) has less switches than PSN(4, m, n) by N1/2 times for a BD with 2sn pins. In the paper, we will use this PSN structure to implement FPIC which can be applied in PSiP (Programmable System in a Package) or PSoC (Programmable System on a Chip) system. Because in the system of PSiP and PSoC, BD (Bare Die)/ Hard IP (Hard Intellectual Property Core) has a lot of pins, the system using PSN would have better area utilization. We lay out FPIC which use PSN(4s, m , n) by cell-based design method. The implementation result of PSN shows that when BD/Hard IP pins between 64 and 128, the needed layout area of FPIC with PSN(8, m , n), s=2 (8-side switch network), is the smallest. The result also show that the needed layout area of a FPIC has positive correlation to the needed switch numbers.
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Lozano, Karen. "Solubility and rheological examination of buckminsterfullerene in decalin and PSVS." Thesis, 1996. http://hdl.handle.net/1911/14086.
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The structure-property relationships of C$\sb{60}$ dissolved in decahydronaphtalene (decalin) and a petroleum solvent viscous standard (PSVS) were studied. This work was motivated mainly by the interest to improve fullerene dispersion in powder processing and the development of a viscoelastic standard for commercial use. Decalin was selected based on the amount of fullerene it can hold, the toxicity grade, rate of evaporation, and inability to interfere with the test method. The PSVS is a standard for viscous calibration of rheological instruments. Measurements of solubility, density, viscosity and elasticity values were conducted. The results are for samples classified as 0, 25, 50, 75 and 100% of C$\sb{60}$ saturation level. Decalin can dissolve 1.9 mg/ml of C$\sb{60}$ while the PSVS only dissolves 0.15 mg/ml. The viscosity behavior shown by both solvents was Newtonian, with a small increase in viscosity as a function of fullerene concentration. The elastic portion of the solvents did not change with fullerene concentration.
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Vakilalroayaei, Hessam. "Dynamic Behaviour of Coke Drums PSVs During Blocked Outlet Condition." Thesis, 2009. http://hdl.handle.net/10012/4382.
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The maximum yield taken in an oil refinery can not exceed 70% without including Delayed Coker Unit (DCU) as part of unit operations in the refinery. This implies naturally a big attraction on investing of such a unit for refiners. However, during the past decades, there were few refiners included Coker unit in the refinery, due to the fact of its large capital investment with a high marginal profitability. On the other hand the technologies developed to operate a coker unit, involve a series of process steps that require highly trained and well experienced operators with a state of art of design to overcome all the challenges with this unit operation. Safety, as a prime factor of design and operation requires much attention in the design of this unit.
Among different safety consideration in the design and operation of Coker Unit, this project thesis focuses on the dynamic behaviour of Coke Drums PSV (Process Safety Valve) relief and its interaction with Blowdown section of the unit that leads also to the PSV relief of Blowdown section with change of temperature versus time during the first 15 minutes that is considered as the time required for operators intervention.
The main findings in this thesis are about the complications in the design aspects of delayed coker unit as well as the importance and role of safety of operation of this unit. It also gave me an insight of cascade relief during the upset condition in an online coke drum and the importance of a reliable piping system to handle the hydraulics as well high temperature conditions.
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Menano, Francisco Inpotong Castro. "The Bundesverfassungsgericht PSPP Decision : a blow to the European project." Master's thesis, 2021. http://hdl.handle.net/10400.14/34790.
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The German Federal Constitutional Court sent shockwaves across Europe on 5 May 2020, when it declared a ruling by the European Court of Justice and ECB decisions as ultra vires and established a three-month transitional period for the ECB Governing Council to provide further justification in order to ascertain the legality of its measures, which the ECJ had already confirmed.
The ruling is unprecedented and is likely to inflame the already existing tensions between national and European sovereignty. This is more so when the contested ECB programme amounts to the Public Sector Purchase Programme, an exceptional bond-buying measure launched in 2015 and deemed pivotal to combat the lasting effects of the European sovereign debt crisis. In times of increased spending by the EU, the schism between net contributors and beneficiaries is prone to show and is likely deepened by the asymmetric impact of economic crises on MS.
As Europe faces the rise of nationalism, a public health crisis and a consequent economic crisis caused by the Covid-19 pandemic, the decision could not have come at a worse time. The Bundesverfassunsgericht’s ruling is one that underscores dissent at a time where solidarity is much needed. The decision constitutes a significant drawback to the consistency and effectiveness of the EU legal order as it openly defies well-established rules and foundations. Furthermore, it is likely to serve as an opportunity for illiberal regimes to push their anti-rule of law agenda as well as pave the way for the undermining of further exceptional ECB programmes such as the Pandemic Emergency Purchase Programme.
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"Análisis, función y aplicaciones biotecnológicas de las proteínas del plasma seminal de porcino PSP-I y PSP-II." Universidad de Murcia, 2007. http://www.tesisenred.net/TDR-0206108-101519/.
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Gouveia, Ana Raquel Duarte Frazão de Filipe. "O exercício do poder disciplinar na PSP." Master's thesis, 2014. http://hdl.handle.net/10071/10111.
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O exercício do poder disciplinar é uma constante no seio da PSP, sobretudo porque os titulares deste poder, face não só ao crescendo de importância do papel das forças policiais junto da nossa sociedade, no contexto dos dias de hoje, mas também à complexidade das competências atribuídas a estas forças, têm de zelar pela imagem da Instituição para que a sua autoridade e profissionalismo não sejam postos em causa.
Sabemos que a temática do poder disciplinar é por si só complexa e, não raras vezes, discutida pela doutrina e jurisprudência. Não obstante, cremos que a complexidade aumenta no seio da PSP, não só por estarmos perante um procedimento com uma tramitação própria, mas também porque está em vigor um regulamento disciplinar aprovado pela Lei n.º 7/90, de 20 fevereiro, não tendo até aos dias de hoje sofrido qualquer alteração de raiz, contrariamente ao que sucede com o exercício do poder disciplinar junto dos trabalhadores que exercem funções públicas, em regime de contrato de trabalho, que sofreu alterações com a entrada em vigor da Lei n.º 35/2014, de 20 de junho.
A presente tese procura, assim, debruçar-se sobre algumas das questões mais complexas, pretendendo clarificar as mesmas, tendo como objetivo final coadjuvar aqueles que pretendam estudar esta temática.
Na parte final são apresentados os dados mais relevantes e que melhor refletem a forma como o poder disciplinar é exercido na PSP.
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"Estudio del plasma seminal y la espermadhesina PSP-I/PSP-II sobre la funcionalidad de los espermatozoides de verraco." Universidad de Murcia, 2007. http://www.tesisenred.net/TDR-0514107-133059/.
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Costa, Cristina. "Avaliação do desempenho na Polícia de Segurança Pública (PSP)- Estudo de caso do Comando Distrital da PSP de Braga." Master's thesis, 2016. http://hdl.handle.net/11110/1063.
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Com esta dissertação pretende-se estudar o modelo de avaliação de desempenho existente na Polícia de Segurança Pública (PSP), a nível central e a nível do Comando Distrital da PSP de Braga, bem como a forma como ambos os modelos se articulam.Tendo em conta a revisão de literatura efetuada, constata-se que a avaliação de desempenho tem vindo a assumir um papel importante na Polícia, sendo útil para melhorar os serviços prestados,apoiar na tomada de decisões, responsabilizar os gestores e prestar contas à sociedade. A literatura refere ainda que a Polícia é um serviço difícil de avaliar devido à diversidade de atividades que esta desenvolve e à dificuldade em aferir a segurança dos cidadãos e a redução da
criminalidade.Para se perceber o modelo de avaliação existente na PSP propõe-se fazer um estudo de caso,através de entrevistas, contando com a colaboração do Diretor Nacional Adjunto da Unidade Orgânica de Recursos Humanos, do 2º Comandante Distrital do Comando Distrital de Braga e do Diretor do Gabinete de Estudos e Planeamento da Direção Nacional da PSP.Neste estudo verifica-se que o modelo de avaliação de desempenho da PSP é um modelo
centralizado uma vez que é a Direção Nacional (DN) da PSP que define os objetivos estratégicos, os objetivos operacionais, os indicadores e as metas para todo o seu universo. Os resultados desta avaliação são apresentados no Relatório de Atividades da PSP. A nível central também é utilizado o Sistema Integrado de Gestão e Avaliação de Desempenho na Administração Pública – Quadro de Avaliação e Responsabilidades (SIADAP – QUAR). Por outro lado, ao nível do Comando Distrital de Braga verifica-se que não existe um modelo de avaliação de desempenho. Estes recebem a informação sobre os objetivos operacionais, os indicadores e as metas a atingir estabelecidas pela DN, que tentam cumprir num determinado período e no final comunicam-lhes os resultados. A DN agrega todos os resultados a nível Nacional e faz a avaliação global do desempenho da PSP.O estudo mostra ainda que há uma forte predisposição para a implementação de um modelo de avaliação de desempenho baseado na metodologia Balanced Scorecard (BSC), por este ser considerado um modelo eficaz, com larga utilização a nível mundial e com bons resultados alcançados. Atualmente a DN já define o seu quadro estratégico baseado nas quatro perspetivas do BSC: perspetiva do cliente, perspetiva financeira, perspetiva dos processos internos e perspetiva da aprendizagem. Contudo, até ao momento não são apresentados os resultados desta avaliação de acordo com o modelo BSC. Conclui-se, por isso, que o modelo de avaliação existente na PSP é um modelo extremamente
centralizado na DN, sendo reduzido o envolvimento dos Comandos Distritais neste processo.
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Costa, Cristina da Silva. "Avaliação do desempenho na Polícia de Segurança Pública (PSP) - estudo de caso do Comando Distrital da PSP de Braga." Master's thesis, 2016. http://hdl.handle.net/11110/1153.
Full textAbstract:
Com esta dissertação pretende-se estudar o modelo de avaliação de desempenho existente na
Polícia de Segurança Pública (PSP), a nível central e a nível do Comando Distrital da PSP de
Braga, bem como a forma como ambos os modelos se articulam.
Tendo em conta a revisão de literatura efetuada, constata-se que a avaliação de desempenho tem
vindo a assumir um papel importante na Polícia, sendo útil para melhorar os serviços prestados,
apoiar na tomada de decisões, responsabilizar os gestores e prestar contas à sociedade. A
literatura refere ainda que a Polícia é um serviço difícil de avaliar devido à diversidade de
atividades que esta desenvolve e à dificuldade em aferir a segurança dos cidadãos e a redução da
criminalidade.
Para se perceber o modelo de avaliação existente na PSP propõe-se fazer um estudo de caso,
através de entrevistas, contando com a colaboração do Diretor Nacional Adjunto da Unidade
Orgânica de Recursos Humanos, do 2º Comandante Distrital do Comando Distrital de Braga e do
Diretor do Gabinete de Estudos e Planeamento da Direção Nacional da PSP.
Neste estudo verifica-se que o modelo de avaliação de desempenho da PSP é um modelo
centralizado uma vez que é a Direção Nacional (DN) da PSP que define os objetivos estratégicos,
os objetivos operacionais, os indicadores e as metas para todo o seu universo. Os resultados
desta avaliação são apresentados no Relatório de Atividades da PSP. A nível central também é
utilizado o Sistema Integrado de Gestão e Avaliação de Desempenho na Administração Pública –
Quadro de Avaliação e Responsabilidades (SIADAP – QUAR).
Por outro lado, ao nível do Comando Distrital de Braga verifica-se que não existe um modelo de
avaliação de desempenho. Estes recebem a informação sobre os objetivos operacionais, os
indicadores e as metas a atingir estabelecidas pela DN, que tentam cumprir num determinado
período e no final comunicam-lhes os resultados. A DN agrega todos os resultados a nível
Nacional e faz a avaliação global do desempenho da PSP.
O estudo mostra ainda que há uma forte predisposição para a implementação de um modelo de
avaliação de desempenho baseado na metodologia Balanced Scorecard (BSC), por este ser
considerado um modelo eficaz, com larga utilização a nível mundial e com bons resultados
alcançados. Atualmente a DN já define o seu quadro estratégico baseado nas quatro perspetivas
do BSC: perspetiva do cliente, perspetiva financeira, perspetiva dos processos internos e
perspetiva da aprendizagem. Contudo, até ao momento não são apresentados os resultados desta
avaliação de acordo com o modelo BSC.
Conclui-se, por isso, que o modelo de avaliação existente na PSP é um modelo extremamente
centralizado na DN, sendo reduzido o envolvimento dos Comandos Distritais neste processo.