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Journal articles on the topic 'Psychedelics'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Sexton, James D., Michael S. Crawford, Noah W. Sweat, Allyson Varley, Emma E. Green, and Peter S. Hendricks. "Prevalence and epidemiological associates of novel psychedelic use in the United States adult population." Journal of Psychopharmacology 33, no. 9 (2019): 1058–67. http://dx.doi.org/10.1177/0269881119827796.

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Background: Novel psychedelics approximate classic psychedelics, but unlike classic psychedelics, novel psychedelics have been used by humans for a shorter period of time, with fewer data available on these substances. Aims: The purpose of this study was to determine the prevalence of novel psychedelic use and the associations of novel psychedelic use with mental health outcomes. Methods: We estimated the prevalence of self-reported, write-in lifetime novel psychedelic use and evaluated the associations of novel psychedelic use with psychosocial characteristics, past month psychological distre

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Dyck, Erika. "Will psychedelic research and the ‘psychedelic renaissance’ create another generational divide?" Open Access Government 41, no. 1 (2024): 178–79. http://dx.doi.org/10.56367/oag-041-10690.

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Will psychedelic research and the ‘psychedelic renaissance’ create another generational divide? Erika Dyck, Canada Research Chair in History of Health & Social Justice at the University of Saskatchewan, discusses changing attitudes to psychedelics and the challenges in forming a strong evidence base from available psychedelic research. As psychedelics re-emerge in the 21st century, their storied past continues to haunt their future. Tales have circulated of their entanglement in unethical medical research and implication in violent behaviours, including suicides and homicides. Psychedelics

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Letheby, Chris, and Jaipreet Mattu. "Philosophy and classic psychedelics: A review of some emerging themes." Journal of Psychedelic Studies 5, no. 3 (2022): 166–75. http://dx.doi.org/10.1556/2054.2021.00191.

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Abstract Serotonergic (or “classic”) psychedelics have struck many researchers as raising significant philosophical questions that, until recently, were largely unexplored by academic philosophers. This paper provides an overview of four emerging lines of research at the intersection of academic philosophy and psychedelic science that have gained considerable traction in the last decade: selfless consciousness, psychedelic epistemology, psychedelic ethics, and spiritual/religious naturalism. In this paper, we highlight philosophical questions concerning (i) psychedelics, self-consciousness, an

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Kim, Kyurim, Abban Yusuf, Abhimanyu Sud, et al. "Critical appraisal of evidence supporting prescription of psychedelics from clinic websites in Ontario, Canada." PLOS ONE 19, no. 10 (2024): e0309911. http://dx.doi.org/10.1371/journal.pone.0309911.

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Psychedelics, including ketamine, 3,4-Methyl enedioxy methamphetamine (MDMA), and psilocybin, have gained attention for their potential therapeutic role in mental health treatment. While recreational use is prohibited in Canada, medicinal exemptions can be granted. There are several psychedelic clinics in Ontario, Canada, promoting the use of psychedelics for a variety of medical indications. Our objective was to identify the indications for which psychedelics are being prescribed in Ontario clinics and assess the quality of evidence used to support these claims. Internet searches were conduct

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Meling, Daniel, Rebecca Ehrenkranz, Sandeep M. Nayak, et al. "Mind the Psychedelic Hype: Characterizing the Risks and Benefits of Psychedelics for Depression." Psychoactives 3, no. 2 (2024): 215–34. http://dx.doi.org/10.3390/psychoactives3020014.

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Rationale: Psychedelic research re-emerged from a period of suppression into the so-called psychedelic renaissance. In parallel, most media reporting has shifted from the overstatement of the risks of psychedelics to overly positive hype. As the empirical evidence is more equivocal than frequently portrayed, the conclusions about the effectiveness of psychedelics should be considered preliminary. Poor science communication about psychedelics’ therapeutic potential may lead potential participants or patients to feel misled and policy decisions to be misinformed. An evidence-informed characteriz

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Yaden, David B., Matthew W. Johnson, Roland R. Griffiths, et al. "Psychedelics and Consciousness: Distinctions, Demarcations, and Opportunities." International Journal of Neuropsychopharmacology 24, no. 8 (2021): 615–23. http://dx.doi.org/10.1093/ijnp/pyab026.

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Abstract Psychedelic substances produce unusual and compelling changes in conscious experience that have prompted some to propose that psychedelics may provide unique insights explaining the nature of consciousness. At present, psychedelics, like other current scientific tools and methods, seem unlikely to provide information relevant to the so-called “hard problem of consciousness,” which involves explaining how first-person experience can emerge. However, psychedelics bear on multiple “easy problems of consciousness,” which involve relations between subjectivity, brain function, and behavior

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Song-Smith, Charlie, Edward Jacobs, James Rucker, Matthew Saint, James Cooke, and Marco Schlosser. "UK medical students’ self-reported knowledge and harm assessment of psychedelics and their application in clinical research: a cross-sectional study." BMJ Open 14, no. 3 (2024): e083595. http://dx.doi.org/10.1136/bmjopen-2023-083595.

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ObjectiveTo capture UK medical students’ self-reported knowledge and harm assessment of psychedelics and to explore the factors associated with support for changing the legal status of psychedelics to facilitate further clinical research.DesignCross-sectional, anonymous online survey of UK medical students using a non-random sampling method.SettingUK medical schools recognised by the General Medical Council.Participants132 medical students who had spent an average of 3.8 years (SD=1.4; range: 1–6) in medical school.ResultsMost students (83%) reported that they were aware of psychedelic researc

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Dyck, Erika. "The history of psychedelics and why psychedelic stories matter." Open Access Government 39, no. 1 (2023): 194–95. http://dx.doi.org/10.56367/oag-039-10690.

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The history of psychedelics and why psychedelic stories matter Erika Dyck argues that how people learn about psychedelics today matters, based on the histories of these drugs and how they have been and should be used in clinical medicine. While these substances have piqued the interest and influenced the attitudes of individuals across academia, culture, and medicine, expanding before and well after the 1950's, Dr. Dyck notes that psychedelic drugs have had a long and colourful history. However, their history has not come without polarising opinions, as until recently, trends in cultural attit

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Gandy, Sam. "Psychedelics and potential benefits in “healthy normals”: A review of the literature." Journal of Psychedelic Studies 3, no. 3 (2019): 280–87. http://dx.doi.org/10.1556/2054.2019.029.

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We are in the midst of a psychedelic research renaissance. With research examining the efficacy of psychedelics as a treatment for a range of mental health indications still in its early stages, there is an increasing body of research to show that careful use of psychedelics can yield a variety of beneﬁts in “healthy normals” and so lead to “the betterment of well people.” Psychedelics have been found to modulate neuroplasticity, and usage in a supportive setting can result in enduring increases in traits such as well-being, life satisfaction, life meaning, mindfulness, and a variety of measur

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Burt, Isaac. "Integrating Psychedelics into Groupwork: A Culturally Responsive Model for the Counseling Profession." Psychoactives 3, no. 3 (2024): 357–64. http://dx.doi.org/10.3390/psychoactives3030022.

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Psychedelics, combined with talk therapy, indicate promise with challenging clients, such as those struggling with PTSD. Furthermore, groupwork, with the emphasis on social connections, can be an effective modality. There appears, however, little movement with integrating psychedelics with professional counseling and even less in groupwork. Societal perceptions of psychedelics and the concern of practicing outside one’s scope may cause practitioners to hesitate. This article provides a brief overview for the lack of progression in implementing psychedelics in group counseling. I explain what p

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Miller, Norman. "Psychedelics: Safety and Efficacy." International Journal of Environmental Research and Public Health 22, no. 2 (2025): 134. https://doi.org/10.3390/ijerph22020134.

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Psychedelic research has experienced a renaissance in recent years, with many researchers exploring the possible therapeutic effects of these drugs. Medical institutions, universities, pharmaceutical companies, and governmental institutions alike have been showing an increase in support of this research, as shown through the recent establishment of various psychedelic research facilities across the United States. However, the safety and efficacy of psychedelic usage are not the focus of the existing research. Additionally, many of the studies on psychedelic use that have already been published

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Lemercier, Clément E., and Devin B. Terhune. "Psychedelics and hypnosis: Commonalities and therapeutic implications." Journal of Psychopharmacology 32, no. 7 (2018): 732–40. http://dx.doi.org/10.1177/0269881118780714.

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Background: Recent research on psychedelics and hypnosis demonstrates the value of both methods in the treatment of a range of psychopathologies with overlapping applications and neurophenomenological features. The potential of harnessing the power of suggestion to influence the phenomenological response to psychedelics toward more therapeutic action has remained unexplored in recent research and thereby warrants empirical attention. Aims: Here we aim to elucidate the phenomenological and neurophysiological similarities and dissimilarities between psychedelic states and hypnosis in order to re

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Neitzke-Spruill, Logan, Nese Devenot, Dominic Sisti, Lynnette A. Averill, and Amy L. McGuire. "Bio-Psycho-Spiritual Perspectives on Psychedelics: Clinical and Ethical Implications." Perspectives in Biology and Medicine 67, no. 1 (2024): 117–42. http://dx.doi.org/10.1353/pbm.2024.a919715.

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ABSTRACT: Psychedelics have again become a subject of widespread interest, owing to the reinvigoration of research into their traditional uses, possible medical applications, and social implications. As evidence for psychedelics' clinical potential mounts, the field has increasingly focused on searching for mechanisms to explain the effects of psychedelics and therapeutic efficacy of psychedelic-assisted therapy (PAT). This paper reviews three general frameworks that encompass several prominent models for understanding psychedelics' effects—specifically, neurobiological, psychological, and spi

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Nayak, Sandeep M., Natalie Gukasyan, Frederick S. Barrett, Earth Erowid, Fire Erowid, and Roland R. Griffiths. "Classic Psychedelic Coadministration with Lithium, but Not Lamotrigine, is Associated with Seizures: An Analysis of Online Psychedelic Experience Reports." Pharmacopsychiatry 54, no. 05 (2021): 240–45. http://dx.doi.org/10.1055/a-1524-2794.

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Abstract Introduction Psychedelics show promise in treating unipolar depression, though patients with bipolar disorder have been excluded from recent psychedelic trials. There is limited information on the use of classic psychedelics (e. g., LSD or psilocybin) in individuals using mood stabilizers to treat bipolar disorder. This is important to know, as individuals with bipolar depression may attempt to treat themselves with psychedelics while on a mood stabilizer, particularly given enthusiastic media reports of the efficacy of psilocybin for depression. Methods This study analyzed reports of

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Lindegaard, Tomas. "Do Psychedelics Facilitate Emergence of Unconscious Psychological Processes?" Psychodynamic Psychiatry 51, no. 3 (2023): 270–86. http://dx.doi.org/10.1521/pdps.2023.51.3.270.

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Psychedelic substances have a long history of use in traditional healing and religious ceremonies worldwide and are increasingly being investigated for their possible therapeutic usage. However, there is still a lack of consensus regarding how best to characterize the psychological effects of psychedelics and how they bring about the positive therapeutic outcomes observed in clinical studies. The aim of this article is to review available evidence from quantitative and qualitative studies on psychedelic-assisted therapy, as well as neurobiological studies, in relation to the hypothesis that ps

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Noorani, Tehseen. "Making psychedelics into medicines: The politics and paradoxes of medicalization." Journal of Psychedelic Studies 4, no. 1 (2019): 34–39. http://dx.doi.org/10.1556/2054.2019.018.

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This commentary considers efforts to turn psychedelics into medications that can be administered through healthcare systems as examples of “medicalization.” I draw on ethnographic research both inside and outside of university-based clinical trials from 2014 to date, together with analogous examples from psychiatry and drug research and development. Rather than taking a normative stance on medicalization, I situate it in a wider political, economic, and cultural context to better understand its logics and effects. I begin by suggesting the resurgence of psychedelic science has been concerned w

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Carhart-Harris, Robin. "4 Psychedelics: therapeutic mechanisms." Journal of Neurology, Neurosurgery & Psychiatry 91, no. 8 (2020): e2.2-e2. http://dx.doi.org/10.1136/jnnp-2020-bnpa.4.

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Robin Carhart-Harris moved to Imperial College London in 2008 after obtaining a PhD in Psychopharmacology from the University of Bristol and an MA in Psychoanalysis from Brunel University. At Imperial, he has designed and/or carried out brain imaging studies involving LSD, psilocybin, MDMA and DMT, plus a clinical trial of psilocybin for treatment-resistant depression, and an ongoing study comparing psilocybin with escitalopram for major depressive disorder. In 2019, he set-up the Centre for Psychedelic Research at Imperial and he also an honorary position with the University of Oxford.The tal

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Lowe, Henry, Ngeh Toyang, Blair Steele, et al. "The Therapeutic Potential of Psilocybin." Molecules 26, no. 10 (2021): 2948. http://dx.doi.org/10.3390/molecules26102948.

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The psychedelic effects of some plants and fungi have been known and deliberately exploited by humans for thousands of years. Fungi, particularly mushrooms, are the principal source of naturally occurring psychedelics. The mushroom extract, psilocybin has historically been used as a psychedelic agent for religious and spiritual ceremonies, as well as a therapeutic option for neuropsychiatric conditions. Psychedelic use was largely associated with the “hippie” counterculture movement, which, in turn, resulted in a growing, and still lingering, negative stigmatization for psychedelics. As a resu

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Dailey, Patricia. "Inventing Experience: Medieval, Psychedelic, and Postmodern." South Atlantic Quarterly 124, no. 2 (2025): 307–24. https://doi.org/10.1215/00382876-11626633.

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What kind of experience is “literary experience,” and what might it have in common with psychedelics? This essay exposes a poetics of experience embedded within psychedelics and shows its common ground with the literary space of a poem in the Middle Ages. While writers like Aldous Huxley have often appealed to the precursor of the medieval, this essay takes a different turn. By looking at the co-substantial way in which reality is displaced, suspended, and refigured in a different register, the author proposes to show how literary works like the medieval “dream-vision,” the “trip/journey,” or

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Brasher, Trey, David Rosen, and Marcello Spinella. "Psychedelics and psychological strengths." International Journal of Wellbeing 13, no. 1 (2023): 1–35. http://dx.doi.org/10.5502/ijw.v13i1.2325.

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Classical psychedelics appear efficacious in improving psychological well-being in randomized clinical trials, but their effects in the population at large are relatively unknown. In the present paper, which includes three studies conducted by online survey with a collective 3,157 participants, classical psychedelic users showed greater psychological strengths and well-being, and lower levels of distress, after controlling for demographic variables, respondents’ beliefs about the potential benefits of psychedelics, and their use of other psychoactive drugs. These benefits contrast with pattern

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Butler, Matthew, Mathieu Seynaeve, Timothy R. Nicholson, et al. "21 Psychedelic treatment of functional neurological disorder – a systematic review." Journal of Neurology, Neurosurgery & Psychiatry 91, no. 8 (2020): e16.2-e17. http://dx.doi.org/10.1136/jnnp-2020-bnpa.38.

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AimsFunctional neurological disorder (FND), formerly known as conversion disorder, causes a high burden of disability and distress, and is amongst the most commonly encountered conditions in neurology clinics and neuropsychiatry services, yet the therapeutic evidence base is limited. Research into psychedelics such as psilocybin and lysergic acid diethylamide (LSD) is currently being undertaken with significant renewed interest, and in recent studies psychedelics have shown promise in treating a range of psychiatric conditions. Modification of neural circuits associated with self-representatio

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Reiff, Collin M., Elon E. Richman, Charles B. Nemeroff, et al. "Psychedelics and Psychedelic-Assisted Psychotherapy." FOCUS 19, no. 1 (2021): 95–115. http://dx.doi.org/10.1176/appi.focus.19104.

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Reiff, Collin M., Elon E. Richman, Charles B. Nemeroff, et al. "Psychedelics and Psychedelic-Assisted Psychotherapy." American Journal of Psychiatry 177, no. 5 (2020): 391–410. http://dx.doi.org/10.1176/appi.ajp.2019.19010035.

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Doty, Michael. "Psychedelic-Informed Experiential Research." Integral Transpersonal Journal 13, no. 13 (2019): 63–73. http://dx.doi.org/10.32031/itibte_itj_13-dm4.

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Early in the life of transpersonal psychology, Tart (1972) proposed the use of altered states of consciousness, including those brought on by psychedelic substances, as research tools. Drawing on recent research on established transpersonal research methods and the neurological effects of psychedelics, this article proposes the use of Psychedelic-Informed Experiential Research to add depth and understanding to all stages of the research process. KEYWORDS Psychedelics, brain, DAN, states of consciousness

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Hogea, Lavinia, Dana Cătălina Tabugan, Iuliana Costea, et al. "The Therapeutic Potential of Psychedelics in Treating Substance Use Disorders: A Review of Clinical Trials." Medicina 61, no. 2 (2025): 278. https://doi.org/10.3390/medicina61020278.

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Substance use disorders (SUDs) affect millions worldwide. Despite increasing drug use, treatment options remain limited. Psychedelic-assisted therapy (PAT), integrating psychedelic substances with psychotherapy, offers a promising alternative by addressing underlying neural mechanisms. This review’s purpose is to investigate the current understanding of psychedelic therapy for treating SUDs, including tobacco, alcohol, and drug addiction. The systematic review approach focused on clinical trials and randomized controlled trials conducted from 2013 to 2023. The search was performed using PubMed

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Evans, Kathryn, Crystian Massengill, and Jonnathan Singh Alvarado. "The role of modern neuroscience in the renaissance of psychedelic research." Revista Costarricense de Psicología 44, no. 1 (2025): 1–23. https://doi.org/10.22544/rcps.v44i01.10.

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The primary objective of this review is to highlight the increasing relevance of experimental neuroscience in advancing the mechanistic understanding and translational potential of classic psychedelics and other psychoactive substances of interest. First, we review clinical evidence for the therapeutic potential of psychedelics in the context of depression, anxiety, and addiction. Second,we review recent basic neuroscientific findings regarding the molecular and neural circuit bases of psychedelic action, with a focus on contributions from systems neuroscience. We survey recent advances in exp

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Irvine, Alexander, David Luke, Freya Harrild, Sam Gandy, and Rosalind Watts. "Transpersonal Ecodelia: Surveying Psychedelically Induced Biophilia." Psychoactives 2, no. 2 (2023): 174–93. http://dx.doi.org/10.3390/psychoactives2020012.

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Objective: To explore the perceived influence of psychedelic experiences on participants’ relationship with the natural world. Method: A total of 272 participants reporting previous use of psychedelics completed free-text response requests via an online survey. Thematic analysis was used to explore group participant responses. Results: Participants who described a pre-existing relationship with nature reported that psychedelics acted to re-establish and bolster their connection to nature. Those reporting no previously established connection to nature described psychedelics as helping them bond

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Trajbarič, Tamara. "ROLE OF PSYCHEDELIC DRUGS IN MENTAL HEALTH CARE: A NARRATIVE REVIEW." Medicina Academica Integrativa 1, no. 2 (2024): 15–22. https://doi.org/10.47960/3029-3316.2024.2.1.15.

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Good mental health is foundational for individual and societal well-being, enabling resilience, personal growth, and active community engagement. Despite the availability of pharmacological and non-pharmacological treatments, many individuals experience partial or non-response, delayed therapeutic effects, and adverse side effects. Increasingly, individuals are exploring the use of psychedelics for self-guided psychotherapy beyond clinical settings, highlighting their potential for transformative mental health benefits. However, the definition and application of psychedelics vary across contex

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Koslowski, Michael, Matthew W. Johnson, Gerhard Gründer, and Felix Betzler. "Novel Treatment Approaches for Substance Use Disorders: Therapeutic Use of Psychedelics and the Role of Psychotherapy." Current Addiction Reports 9, no. 1 (2021): 48–58. http://dx.doi.org/10.1007/s40429-021-00401-8.

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Abstract Purpose of Review The use of psychedelics in a therapeutical setting has been reported for the treatment of various diagnoses in recent years. However, as psychedelic substances are still commonly known for their (illicit) recreational use, it may seem counterintuitive to use psychedelic therapy to treat substance use disorders. This review aims to discuss how psychedelics can promote and intensify psychotherapeutic key processes, in different approaches like psychodynamic and cognitive behavioral therapy, with a spotlight on the treatment of substance use disorders (SUD). Recent Find

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Dyck, Erika. "What is at stake in the psychedelic renaissance?" Open Access Government 40, no. 1 (2023): 212–13. http://dx.doi.org/10.56367/oag-040-10690.

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What is at stake in the psychedelic renaissance? Professor Erika Dyck, Canada Research Chair in the History of Health & Social Justice, discusses the extensive history and growing medical application of psychedelics known as the psychedelic renaissance. British psychiatrist Ben Sessa re-introduced the concept of the psychedelic renaissance in 2011, suggesting that it was perhaps time to rethink the role of psychedelic drugs in medicine. The idea has gained momentum, especially in places like the United States and Europe, where psychedelics had been part of psychiatric reforms in the middle

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Hartogsohn, Ido. "A media ecology perspective on psychedelics." Explorations in Media Ecology 23, no. 1 (2024): 5–11. http://dx.doi.org/10.1386/eme_00188_1.

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Psychedelic drugs present an intriguing variation on the widely circulated maxim that the medium is the message. Psychedelics are commonly defined as non-specific agents without intrinsic effects, and their effects are described as crucially dependent on internal and external contexts (commonly referred to as set and setting). Psychedelics can therefore be understood as a medium defined by its exceptional pliability and amenability to contextual cues. It thus follows that the effects of psychedelics as a medium are crucially embedded and shaped by their surrounding media. This article observes

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Garakani, Amir, Jeanne L. Alexander, Calvin R. Sumner, et al. "Psychedelics, With a Focus on Psilocybin: Issues for the Clinician." Journal of Psychiatric Practice 29, no. 5 (2023): 345–53. http://dx.doi.org/10.1097/pra.0000000000000729.

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There has been a burgeoning interest in psychedelics among the public, state legislatures, psychiatrists and other clinical providers, and within the research community. Increasing numbers of studies evaluating psychedelics for depression, anxiety, posttraumatic stress disorder, and substance use disorders have been conducted or are underway. While discussing psychedelics in general, the focus of this paper is on psilocybin and its mechanism, how it exerts a psychedelic effect, dosing, and a review of the treatment studies of psilocybin, which were primarily for treatment-resistant depression

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Bosshardt, Zachary, Jessica L. Maples-Keller, Deanna M. Kaplan, et al. "Reading the crowd: attitudes toward psychedelics and psychedelic therapies among attendees at a conference." Psychedelics, December 17, 2024, 1–7. https://doi.org/10.61373/pp024r.0040.

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Social attitudes, policy, and perceptions of psychedelics are currently undergoing considerable change. Growing public salience of psychedelics has been accompanied by the emergence of conferences focused on psychedelic education and dialogue. Attendees at such events compose an important group of stakeholders in psychedelic science and practice; their views of psychedelics can be valuable for understanding the current status of this emerging field. For this study, a survey was administered to attendees (N = 178) at an academic conference focused on two topics: psychedelics and spiritual care.

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Kangaslampi, Samuli, and Morten Lietz. "Psychedelics and autobiographical memory – six open questions." Psychopharmacology, March 17, 2025. https://doi.org/10.1007/s00213-025-06771-5.

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Abstract Rationale Since the earliest LSD research, psychedelics have been claimed to enhance autobiographical memory. Revisiting and processing autobiographical memories has further been suggested to be a major component of the therapeutic action of psychedelics. However, modern psychedelic research has largely neglected autobiographical elements of psychedelic experiences, and many vital questions remain unanswered. Objectives We present and discuss six open questions related to psychedelics and autobiographical memory: (1) Do psychedelics enhance autobiographical recall? (2) Is recall and p

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Nadeem, Zohaib, Stephen Parker, Hugh McGovern, and Lena KL Oestreich. "Attitudes toward psychedelics and psychedelic-assisted therapy among potential mental health service users and the general population in Australia." Australian & New Zealand Journal of Psychiatry, June 22, 2024. http://dx.doi.org/10.1177/00048674241261779.

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Objective: Despite rapid advances in psychedelic sciences and the increasing number of countries legalizing psychedelics for the treatment of mental illnesses, the attitudes, knowledge and readiness of both mental health consumers and the general population remain largely unknown. Methods: A cross-sectional survey was conducted among Australians, targeting individuals with mental illness as potential mental health service users. A sub-sample of individuals free of mental illness was also surveyed to assess attitudes in the general population. Participants completed the Attitudes on Psychedelic

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Bartlett, Amy, Challian Christ, Bradford Martins, Kellen Saxberg, and Terence H. W. Ching. "The library is open: a scoping review on queer representation in psychedelic research." Frontiers in Public Health 12 (December 11, 2024). https://doi.org/10.3389/fpubh.2024.1472559.

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The intersection of queer identity and psychedelics has not been thoroughly explored by the research community, historically or in the present day. With growing access to legal psychedelic therapies, it is essential that queer psychedelic experiences are understood sufficiently by clinicians in order to provide the most safe and effective care possible. Psychedelics and queerness are intricately related, and there is strong interest in the use of psychedelics for healing and identity development among queer populations. However, the vast majority of the literature stigmatizes and problematizes

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Kious, Brent, Zach Schwartz, and Benjamin Lewis. "Should we be leery of being Leary? Concerns about psychedelic use by psychedelic researchers." Journal of Psychopharmacology, November 15, 2022, 026988112211334. http://dx.doi.org/10.1177/02698811221133461.

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Psychedelic research is proceeding rapidly, despite ongoing legal and regulatory barriers and lingering questions about study design, such as the difficulty of ensuring adequate blinding, the relative overrepresentation in studies of participants who have previously used psychedelics, and the importance of personal experience with psychedelics for those who provide psychedelic-assisted therapy. Here we wish to explore a distinct concern: whether personal use of psychedelics by researchers could threaten the objectivity and ethical conduct of psychedelic research itself. In 2020, Anderson et al

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Greer, J. Christian. "Beyond Counterculture: Towards a People’s History of Psychedelic Networks." Psychedelic Intersections 1, no. 1 (2025). https://doi.org/10.70423/0001.07.

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This article demonstrates how “counterculture” remains a poorly defined way to talk about rapidly developing milieux, scenes, and networks born out of the religious awakening stimulated by psychedelics in the mid-1960s. It proposes an alternative framework of “psychedelicism” to better understand the nuances and complexity of historical and contemporary psychedelic communities.

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Gorman, Ingmar, Elizabeth M. Nielson, Aja Molinar, Ksenia Cassidy, and Jonathan Sabbagh. "Psychedelic Harm Reduction and Integration: A Transtheoretical Model for Clinical Practice." Frontiers in Psychology 12 (March 15, 2021). http://dx.doi.org/10.3389/fpsyg.2021.645246.

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Psychedelic Harm Reduction and Integration (PHRI) is a transtheoretical and transdiagnostic clinical approach to working with patients who are using or considering using psychedelics in any context. The ongoing discussion of psychedelics in academic research and mainstream media, coupled with recent law enforcement deprioritization of psychedelics and compassionate use approvals for psychedelic-assisted therapy, make this model exceedingly timely. Given the prevalence of psychedelic use, the therapeutic potential of psychedelics, and the unique cultural and historical context in which psychede

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King IV, Franklin. "Psychedelic Projections: Hidden Narratives Shaping Psychedelic Medicine." Psychedelic Intersections 1, no. 1 (2025). https://doi.org/10.70423/0001.17.

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Psychedelics can evoke powerful projections not only for those under the influence of these substances but also for those who study them. As Timothy Leary once quipped, “LSD [is a psychedelic drug that] occasionally causes psychotic behavior in people who have not taken it.” This speaks to how the idea of psychedelics can be polarizing, political, and often poorly defined. While psychedelic substances are mere molecules, “psychedelic” as a concept is a blank canvas onto which all manner of biases, agendas, and beliefs can be projected. Consequently, psychedelics often mean different things to

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Boehnke, Kevin F., Kasey Cox, Cody Weston, et al. "Slouching towards engagement: interactions between people using psychedelics naturalistically and their healthcare providers." Frontiers in Psychiatry 14 (August 4, 2023). http://dx.doi.org/10.3389/fpsyt.2023.1224551.

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IntroductionThere is substantial public interest in psychedelics as potential treatments for psychiatric conditions. However, most psychedelics are criminalized under federal law in the USA, so it is unclear whether use occurs with clinical support. Our objective was to assess whether naturalistic psychedelic use occurs with clinical support, interactions between those using psychedelics and healthcare providers (psychiatrist, therapist, or primary physicians), and use characteristics.MethodsWe conducted an online, anonymous, confidential, cross-sectional survey of adults reporting psychedelic

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Prostko, Sara, Alexander Wu, Samuel Maddams, et al. "Attitudes Toward Psychedelic Treatments by Individuals With Histories of Substance Use or Psychiatric Disorders: A Survey Study." Journal of Addiction Medicine, May 28, 2025. https://doi.org/10.1097/adm.0000000000001517.

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Objectives: Psychedelics may be promising treatments for substance use disorders (SUD). This study aims to understand how individuals with alcohol use disorder (AUD), opioid use disorder (OUD), and psychiatric disorders perceive and experience psychedelics for both nonmedical and medical use. Methods: Data for this cross-sectional survey study were collected from June 2023 to February 2024 at a large, tertiary hospital through the hospital’s patient portal, inpatient floors, and flyers. English-speaking adults with AUD, OUD, and psychiatric disorders were recruited. The response rate was 1.9%

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Pace, Brian A., and Neşe Devenot. "Right-Wing Psychedelia: Case Studies in Cultural Plasticity and Political Pluripotency." Frontiers in Psychology 12 (December 10, 2021). http://dx.doi.org/10.3389/fpsyg.2021.733185.

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Recent media advocacy for the nascent psychedelic medicine industry has emphasized the potential for psychedelics to improve society, pointing to research studies that have linked psychedelics to increased environmental concern and liberal politics. However, research supporting the hypothesis that psychedelics induce a shift in political beliefs must address the many historical and contemporary cases of psychedelic users who remained authoritarian in their views after taking psychedelics or became radicalized after extensive experience with them. We propose that the common anecdotal accounts o

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Carroll, Thomas. "The Psychedelic Renaissance: A Catholic Perspective." Linacre Quarterly, September 15, 2024. http://dx.doi.org/10.1177/00243639241274818.

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After being outlawed in 1970, psychedelics have reemerged in the consciousness of Western society in the form of the so-called psychedelic renaissance. This has led to widespread interest in psychedelic compounds being used for recreation, treatment of mental illness and addiction, and even the so-called “enhancement” of individuals and society. This renewed interest in psychedelics has resulted in seemingly endless publications in both the popular and the academic press, including authors from fields as diverse as philosophy, theology, pharmacology, neuroscience, and clinical medicine. A comm

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Wolinsky, David, Frederick Streeter Barrett, and Ryan Vandrey. "The psychedelic effects of cannabis: A review of the literature." Journal of Psychopharmacology, November 10, 2023. http://dx.doi.org/10.1177/02698811231209194.

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Cannabis and classic psychedelics are controlled substances with emerging evidence of efficacy in the treatment of a variety of psychiatric illnesses. Cannabis has largely not been regarded as having psychedelic effects in contemporary literature, despite many examples of historical use along with classic psychedelics to attain altered states of consciousness. Research into the “psychedelic” effects of cannabis, and delta-9-tetrahydrocannabinol (THC) in particular, could prove helpful for assessing potential therapeutic indications and elucidating the mechanism of action of both cannabis and c

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Plesa, Patric, and Rotem Petranker. "Psychedelics and neonihilism: connectedness in a meaningless world." Frontiers in Psychology 14 (August 9, 2023). http://dx.doi.org/10.3389/fpsyg.2023.1125780.

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The resurgence of psychedelic research explicitly targets treating mental health conditions largely through psychedelics-assisted psychotherapy. Current theories about mechanisms of change in psychedelics-assisted psychotherapy focus on mystical experiences as the main driver of symptom improvement. During these mystical experiences, participants report an enhanced sense of salience, connectedness, and meaning. Simultaneously, a growing psychedelic culture is also cultivating the use of psychedelics as medicine for relieving symptoms of anxiety and depression and promoting cognitive functions.

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Enghoff, Oskar, Margit Anne Petersen, Søren Holm, and Morten Hesse. "Turning online to tune in: Psychedelic information seeking in an era of renewed psychedelic curiosity." Journal of Psychedelic Studies, May 16, 2025. https://doi.org/10.1556/2054.2025.00415.

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AbstractBackground and aimsOnline platforms are popular for exchanging information about psychedelics, including consumption advice. The recent resurgence of public interest in psychedelics will likely intensify this. We aim to further the understanding among researchers, policy makers, medical practitioners, harm reduction practitioners, and social workers, of contemporary psychedelic information exchange and its impact on consumption. With a social learning perspective and a focus on online content, we investigate the use of various sources and types of information by people who have used ps

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Li, Irene, Rodney Fong, Molly Hagen, and Burton Tabaac. "Medical student attitudes and perceptions of psychedelic-assisted therapies." Frontiers in Psychiatry 14 (June 27, 2023). http://dx.doi.org/10.3389/fpsyt.2023.1190507.

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IntroductionAlthough certain psychedelic agents may soon gain federal approval for use in treating specific psychiatric conditions, the utilization of such therapies in clinical practice will depend largely on the attitudes of healthcare providers. Therefore, this study assesses the current attitudes, knowledge, exposure, and acceptance of psychedelics and psychedelic-assisted therapies amongst medical students.MethodsIn fall semester of 2022, surveys were emailed to 580 medical students attending medical institutions in the state of Nevada in the United States. Utilizing knowledge and attitud

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Falcon, Joshua. "Anthropology of Psychedelics." Anthropology of Consciousness, April 20, 2025. https://doi.org/10.1111/anoc.70002.

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ABSTRACTAnthropologists have studied the use of psychedelic drugs across cultures for over a century; however, this literature has yet to be compiled. In providing a brief survey of ethnographic research produced in the Global North on the ‘classic psychedelics’, this article suggests that there not only exists a robust subfield that can be called the anthropology of psychedelics, but that the field also lacks diversity given that it predominately focuses on the Indigenous use of psychedelics or research at the intersection of Indigenous and Global North encounters. Accordingly, there exists a

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Engel, Liam B., Sascha B. Thal, and Stephen J. Bright. "Psychedelic Forum Member Preferences for Carer Experience and Consumption Behavior: Can “Trip Sitters” Help Inform Psychedelic Harm Reduction Services?" Contemporary Drug Problems, August 29, 2022, 009145092211214. http://dx.doi.org/10.1177/00914509221121420.

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Background: There is limited research on the provision of harm reduction services to people who use psychedelics. Little is known about provision of care to people consuming psychedelics outside of clinical trials. Methods: We investigated how people who used psychedelics discussed their preferences for care (or “trip sitting”) on two online forums: The Shroomery and DMT Nexus. A thematic analysis of the discussion was conducted to better understand consumer preferences for harm reduction services and resources. Results: We identified two key themes: experience and remote sitting. Forum partic

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