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Journal articles on the topic 'Psychotropic drugs – adverse effects'

Author: Grafiati

Published: 26 July 2024

Last updated: 31 July 2025

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1

Goff, Donald C. "Adverse Effects of Psychotropic Drugs." Journal of Clinical Psychopharmacology 14, no. 1 (1994): 83. http://dx.doi.org/10.1097/00004714-199402000-00017.

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Balis, George U. "Adverse Effects of Psychotropic Drugs." Journal of Nervous and Mental Disease 182, no. 3 (1994): 191–92. http://dx.doi.org/10.1097/00005053-199403000-00020.

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MARDER, STEPHEN R. "Adverse Effects of Psychotropic Drugs." American Journal of Psychiatry 152, no. 1 (1995): 146—a—146. http://dx.doi.org/10.1176/ajp.152.1.146-a.

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Khalil, Rami Bou, and Sami Richa. "Thyroid Adverse Effects of Psychotropic Drugs." Clinical Neuropharmacology 34, no. 6 (2011): 248–55. http://dx.doi.org/10.1097/wnf.0b013e31823429a7.

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Gullickson, Terri, and Brigittine French. "Review of Adverse Effects of Psychotropic Drugs." Contemporary Psychology: A Journal of Reviews 40, no. 1 (1995): 75. http://dx.doi.org/10.1037/003381.

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Gupta, Ankit, and Rakesh K. Chadda. "Adverse psychiatric effects of non-psychotropic medications." BJPsych Advances 22, no. 5 (2016): 325–34. http://dx.doi.org/10.1192/apt.bp.115.015735.

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SummaryPatients presenting to psychiatrists frequently have comorbid medical conditions for which they are receiving treatment. A range of medications used for treatment of these conditions can have adverse effects resembling psychiatric symptoms. This article presents the results of our review of the literature on psychiatric adverse effects of various non-psychotropic medications, and discusses the mechanisms of such effects, their assessment and management. Among the commonly prescribed drugs found to have psychiatric adverse effects are corticosteroids, anti-Parkinsonian drugs, anti-epilep

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Btissam, RAOUF, Adali I., and Manoudi F. "Adverse Effects of Psychotropic Drugs on Pregnant Women: Retrospective Study of 12 Cases in A Psychiatric Hospital in Marrakech." International Journal of Clinical Science and Medical Research 05, no. 05 (2025): 130–31. https://doi.org/10.5281/zenodo.15561332.

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Abstract This retrospective study analyzes maternal and neonatal adverse effects associated with the use of psychotropic drugs during pregnancy in 12 patients followed between 2021 and 2024 at the CHU psychiatric hospital in Marrakech. Clinical data, types of psychotropic drugs prescribed and complications observed were collected. The results highlight cases of neonatal respiratory distress, prematurity and hypotonia, correlated with exposure to antidepressants and antipsychotics. This study highlights the importance of a rigorous assessment of the benefit-risk balance in a Moroccan context.

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Bhuvaneswar, Chaya G., Ross J. Baldessarini, Veronica L. Harsh, and Jonathan E. Alpert. "Adverse Endocrine and Metabolic Effects of Psychotropic Drugs." CNS Drugs 23, no. 12 (2009): 1003–21. http://dx.doi.org/10.2165/11530020-000000000-00000.

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Vívian Ferreira da Costa, Ana, Larissa De Carvalho Bezerra, and Juliane Dos Anjos de Paula. "Use of psychotropic drugs in the treatment of fibromyalgia: a systematic review." Journal of Human Growth and Development 31, no. 2 (2021): 336–45. http://dx.doi.org/10.36311/jhgd.v31.12228.

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Introduction: The treatment of fibromyalgia is evolving, and more and more drugs are available on the market. Objective: To verify the response, tolerability, and adverse events of the use of psychotropic drugs in the treatment of fibromyalgia. Methods: A systematic review of articles on fibromyalgia and psychotropic medications were carried out, indexed in the MEDLINE database (PUBMED) with the MeSH terms: “fibromyalgia”, “psychotropic drugs,” and “treatment outcome”. Of the 89 studies identified, 23 met the eligibility criteria. Results: It has been seen that some classes of psychotropic med

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Petukhova, A. A., A. A. Panov, Ya V. Malygin, and M. A. Kazanfarova. "Side effects of psychotropic drugs on eye." Russian Journal of Clinical Ophthalmology 21, no. 1 (2021): 29–33. http://dx.doi.org/10.32364/2311-7729-2021-21-1-29-33.

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Any antipsychotics provoke more or less ocular complications. Some of them are relatively harmless (i.e., dark eyelids, conjunctival and corneal pigmentation, mydriasis, nystagmus, dry eye etc.). These adverse effects are resolved spontaneously after treatment discontinuation, drug switching, or prescribing additional therapy. However, the intake of both typical and atypical neuroleptics, lithium salts, some anticonvulsants (e.g., topiramate) is associated with high risks of vision loss. Moreover, in some patients these medications may result in blindness. The use of psychotropic drugs (e.g.,

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G, Siddesha, Justina M. Steefan, and A. Naveen. "Adverse Effects of Antipsychotic Drugs - A Review." International Journal of Research and Review 10, no. 9 (2023): 153–56. http://dx.doi.org/10.52403/ijrr.20230916.

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Antipsychotic drugs which are also known as Neuroleptics are group of psychotropic drugs or psychopharmacological agents1 that are primarily used to manage psychoses including delusions, hallucinations, paranoia, or disordered thought. Besides their antipsychotic action, they had been reported to have some adverse effects which can be seen in Cardiovascular system, Metabolic system, Skeletal and Muscular system, Cognitive and Emotional side effects, and Sexual dysfunction. These adverse effects were mainly observed when they used for longer duration or taken in larger doses or with sudden chan

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Suárez Hernández, Daniel. "SATISFACTION WITH THE INFORMATION RECEIVED TO THE PATIENTS UNDER TREATMENT WITH PSYCHOACTIVE DRUGS." American Journal of Medical and Clinical Research & Reviews 03, no. 04 (2024): 01–03. http://dx.doi.org/10.58372/2835-6276.1167.

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Statement of the problem Our objective in this study is to Know the perception of adverse effects in patients who are being treated with psychotropic medication. We have not found in the reviewed literature another study that emphasizes analysing the factors that influence the perception of side effects of users of psychotropic medication. The incidence of adeverse effects and the information about the effects in patients is a subject not very well Known. There are not many bibliographical references on the degree of satisfaction of the patients about the information received on the effects of

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Gasser, R. W., and H. Resch. "Psychotropic drugs and bone." PAIN, JOINTS, SPINE 14, no. 4 (2025): 226–35. https://doi.org/10.22141/pjs.14.4.2024.441.

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The purpose of this article is to provide an overview of the effects of psychotropic medications on bone metabolism, bone mineral density (BMD), and fracture risk. Methods. The literature search was carried out in PubMed. The keywords used were “osteoporosis”, “bone”, “fracture”, “psychotropic medication”, “antidepressants”, “antipsychotics”, “neuroleptics”, “hyperprolactinemia”, and “lithium”. Results. Psychotropic drugs from the group of antidepressants or neuroleptics (antipsychotics) and lithium preparations have different effects on the bone. On the one hand, they can trigger the developm

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Abid, W., M. Turki, B. Ben jmeaa, et al. "Factors associated with psychotropics adverse effects in elderly psychiatric inpatients." European Psychiatry 67, S1 (2024): S639—S640. http://dx.doi.org/10.1192/j.eurpsy.2024.1326.

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IntroductionAdverse effects (AEs) of psychotropic drugs are more frequent and potentially more dangerous in elderly subjects (ES), probably due to a greater frequency of somatic comorbidities, as well as polymedication.ObjectivesThe aims of this study were to determine the prevalence of AEs of psychotropic treatment among ES hospitalized in psychiatry, and to identify the associated sociodemographic and clinical factors.Methods We conducted a retrospective and descriptive study. It concerned male patients aged at least 60 years, hospitalized in the psychiatry B department at CHU Hedi Chaker (S

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Elmaataoui, Z., H. Belhadga, and H. Kisra. "The metabolic syndrom and the prescription of psychotropic drugs in children and adolescents: three clinical cases." European Psychiatry 66, S1 (2023): S749. http://dx.doi.org/10.1192/j.eurpsy.2023.1577.

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IntroductionAntipsychotics have shown their interest in several pathologies of the child and the adolescent. However, in this vulnerable population, they are not without adverse effects. Depending on the type of molecule used, classical neuroleptics or second generation antipsychotics, but also within these own classes, the profile of tolerance and adverse effects differs. In this sense, children treated with psychotropic drugs have a higher risk of developing metabolic syndrome compared to children who do not take this treatment.ObjectivesThe aim of this work is to discuss the metabolic syndr

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Seifert, Randall D. "Therapeutic Drug Monitoring: Psychotropic Drugs." Journal of Pharmacy Practice 2, no. 6 (1989): 403–15. http://dx.doi.org/10.1177/089719008900200609.

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The therapeutic monitoring of patients who take antipsychotic drugs can be both challenging and rewarding. Antipsychotics have been in clinical use for over 30 years; yet, their complex pharmacology is not fully understood and parallels our infant knowledge of human brain chemistry. The art of successful therapeutic drug monitoring depends on the clinician's knowledge of basic pharmacology, an understanding of psychiatric disorders, and a sensitivity for careful patient observation. In addition, a thorough history, well thought out goals, and reasonable recovery expectations are essential. Ant

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Alderman, Christopher P., and Michael J. Ryan. "Consumer Requests for Information regarding Psychotropic Drugs: Experience from a National Medicines Phone-In." Annals of Pharmacotherapy 31, no. 11 (1997): 1301–5. http://dx.doi.org/10.1177/106002809703101104.

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OBJECTIVE: To undertake a qualitative analysis of calls regarding psychotropic drugs that were received during a national medicines phone-in day. BACKGROUND: In July 1996, The Society of Hospital Pharmacists of Australia coordinated a national medications phone-in day, allowing consumers to seek information about medications from pharmacists and physicians using a toll-free telephone number. METHODS: Data collection forms were used to record the details of all calls answered during the phone-in day. Demographic data collected included the estimated age and gender of the caller. Other data coll

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Goodlet, Kellie J., Monika T. Zmarlicka, and Alyssa M. Peckham. "Drug–drug interactions and clinical considerations with co-administration of antiretrovirals and psychotropic drugs." CNS Spectrums 24, no. 03 (2018): 287–312. http://dx.doi.org/10.1017/s109285291800113x.

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Psychotropic medications are frequently co-prescribed with antiretroviral therapy (ART), owing to a high prevalence of psychiatric illness within the population living with HIV, as well as a 7-fold increased risk of HIV infection among patients with psychiatric illness. While ART has been notoriously associated with a multitude of pharmacokinetic drug interactions involving the cytochrome P450 enzyme system, the magnitude and clinical impact of these interactions with psychotropics may range from negligible effects on plasma concentrations to life-threatening torsades de pointes or respiratory

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Gupta, Sumeet, Mukesh Kripalani, Udayan Khastgir, and Joe Reilly. "Management of the renal adverse effects of lithium." Advances in Psychiatric Treatment 19, no. 6 (2013): 457–66. http://dx.doi.org/10.1192/apt.bp.112.010306.

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SummaryLithium is one of the most effective psychotropic drugs we have, but it is underused because of its low therapeutic index, the need for regular blood tests and perceptions about its adverse effects, including renal problems. The last include urinary concentration deficits and diabetes insipidus, chronic kidney disease (including renal failure), nephrotic syndrome, hypercalcaemia, hyperparathyroidism and distal tubular acidosis. This article reviews these adverse effects with special emphasis on their management.

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ROCK, NICHOLAS L. "Possible Adverse Effects of Buspirone When Used with Other Psychotropic Drugs." Journal of Clinical Psychopharmacology 10, no. 5 (1990): 380. http://dx.doi.org/10.1097/00004714-199010000-00028.

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Mula, Marco. "Psychotropic Effects of Anticonvulsant Drugs in Patients with Epilepsy." Clinical Medicine Insights: Therapeutics 2 (January 2010): CMT.S3285. http://dx.doi.org/10.4137/cmt.s3285.

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Anticonvulsant drugs continue to be the mainstay of epilepsy treatment but benefits of seizure control need to be balanced with the psychotropic potential of this class of compounds. The present paper is aimed at discussing positive and negative effects of anticonvulsant drugs on mood in patients with epilepsy. In general terms, the use in monotherapy, adopting slow titration schedules and low doses when possible, can significantly reduce the occurrence of treatment emergent adverse events. The mental state of the patient need to be taken into account in order to really optimize the anticonvul

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Sepúlveda-Lizcano, Lizeth, Vivian Vanessa Arenas-Villamizar, Enna Beatriz Jaimes-Duarte, et al. "Metabolic Adverse Effects of Psychotropic Drug Therapy: A Systematic Review." European Journal of Investigation in Health, Psychology and Education 13, no. 8 (2023): 1505–20. http://dx.doi.org/10.3390/ejihpe13080110.

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This review aimed to investigate the metabolic alterations associated with psychopharmacological treatment of neuropsychiatric disorders, which can significantly impact patients’ physical health and overall quality of life. The study utilized the PRISMA methodology and included cross-sectional, retrospective studies, and randomized clinical trials from reputable databases like SCOPUS, CLARIVATE, SCIENCE DIRECT, and PUBMED. Out of the 64 selected studies, various psychotropic drug classes were analyzed, including antidepressants, anticonvulsants, and antipsychotics. Among the antidepressants, s

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Botero, Beatriz, Erick Frota Gomes Figueiredo, Jesus Eden Bezerra da Costa, et al. "Efficacy and risks of the use of psychotropics drugs in children and adolescents with depression disorders: a literature review." Research, Society and Development 11, no. 14 (2022): e304111436284. http://dx.doi.org/10.33448/rsd-v11i14.36284.

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The transition from childhood to adolescence is a period of life characterized by hormonal and physiological changes. In this phase, there are also several social interactions that change according to the environment, imposing responsibilities and a desire for new cycles. These demands make people vulnerable and insecure to certain feelings, generating mood disorders that can progress to major depression disorder. Objective: to evaluate the efficacy and risks of psychotropic drugs prescribed to children and adolescents with depression disorders. Method: This is a bibliographic review of scient

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Biering, Páll, and Ingibjörg Hjaltadóttir. "The prevalence of psychiatric diagnoses and psychotropic medication in icelandic nursing homes from 2003 to 2018." Læknablaðið 107, no. 01 (2021): 11–16. http://dx.doi.org/10.17992/lbl.2021.01.615.

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INTRODUCTION: Research shows a high prevalence of mental disorders and psychotropic medication among older people, especially in nursing homes. Knowledge of this concerning issue among Icelandic nursing homes residents is limited, despite its importance for mental health policymaking. Therefore, the aim of this study was to investigate the prevalence of psychiatric diagnoses and psychotropic medication in Icelandic nursing homes, the relationship between these factors and how they have evolved from 2003 to 2018. MATERIAL AND METHODS: The research data comes from interRAI MDS 2.0 assessments fo

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Baldwin, David, and Andrew Mayers. "Sexual side-effects of antidepressant and antipsychotic drugs." Advances in Psychiatric Treatment 9, no. 3 (2003): 202–10. http://dx.doi.org/10.1192/apt.9.3.202.

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Adequate sexual expression is essential to many human relationships and provides a sense of physical, psychological and social well-being. Epidemiological and clinical studies show that depression and schizophrenia are associated with impairment of sexual function and satisfaction, even in untreated patients. Most antidepressant and antipsychotic drugs have adverse sexual effects but it is difficult accurately to identify the incidence of treatment-emergent dysfunction, as disturbances can be reliably detected only from systematic enquiries made at baseline and during treatment. Growing awaren

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Piedad, John, Hugh Rickards, Frank M. C. Besag, and Andrea E. Cavanna. "Beneficial and Adverse Psychotropic Effects of Antiepileptic Drugs in Patients with Epilepsy." CNS Drugs 26, no. 4 (2012): 319–35. http://dx.doi.org/10.2165/11599780-000000000-00000.

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Aktepe, Evrim. "Endocrine and Metabolic Adverse Effects of Psychotropic Drugs in Children and Adolescents." TAF Preventive Medicine Bulletin 10, no. 6 (2011): 741. http://dx.doi.org/10.5455/pmb.20110815113354.

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KANEKO, Koichi. "6．Adverse Effects on Brain Function of Psychotropic Drugs, Corticosteroids and Interferon." Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics 48, no. 2 (2017): 84–90. http://dx.doi.org/10.3999/jscpt.48.84.

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Gurung, Aruna, Jugalkishore B. Jaju, Ganesh R. Pawar, Shrikant C. Dharmadhikari, and Rajvardhan R. Solunke. "Study of drug utilization pattern and adverse drug reactions of psychotropic drugs in psychiatric inpatient department of tertiary care hospital." International Journal of Basic & Clinical Pharmacology 7, no. 2 (2018): 259. http://dx.doi.org/10.18203/2319-2003.ijbcp20180095.

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Background: Mental disorders are now widely recognized as a major contributor to the global burden of disease. The drug use in psychiatric illness is a complex process and because of this the optimal benefits of drug therapy in patient care is not achieved. This often leads to increased cost of medical care, drug resistance, adverse effects and patient mortality. Hence, this study is undertaken to study the drug utilization pattern and adverse drug reactions of psychotropic drugs in psychiatric inpatient department of a tertiary care hospital.Methods: A prospective, observational study was und

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Stimmel, Glen L., and Mary A. Gutierrez. "Sexual Dysfunction and Psychotropic Medications." CNS Spectrums 11, S9 (2006): 24–30. http://dx.doi.org/10.1017/s1092852900026730.

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AbstractPsychotropic drugs are often associated with sexual dysfunction. The frequency of antidepressant-associated sexual dysfunction is greatly underestimated in clinical trials that rely on patient self-report of these adverse events. Direct inquiry reveals that delayed orgasm/ejaculation occurs in ≥50% and anorgasmia in at least one third of patients given selective serotonin reuptake inhibitors. Antidepressant-induced sexual dysfunction can be successfully managed. A different antidepressant without significant sexual effects, such as bupropion or mirtazapine, can often be substituted. Ot

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Florian, A., C. Florian, A. Ignat, et al. "QT Prolongation: Psychotropic medication versus illicit drugs." European Psychiatry 65, S1 (2022): S446. http://dx.doi.org/10.1192/j.eurpsy.2022.1133.

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Introduction Countless substances used for their psychotropic effects may induce adverse cardiac effects, such as QT prolongation. This category of substances holds illicit drugs as well as medications, with their effects influenced by dosage, concomitant use and patient specific factors. The appraisal of cardiac consequences is essential as delayed repolarization may lead to the rare but potentially deadly polymorphic ventricular tachycardia. Objectives The goal of this presentation is to underscore the cardiac risks associated with both medication use and substance abuse in order to ensure t

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Bishara, Delia, Chris Kalafatis, and David Taylor. "Emerging and experimental treatments for COVID-19 and drug interactions with psychotropic agents." Therapeutic Advances in Psychopharmacology 10 (January 2020): 204512532093530. http://dx.doi.org/10.1177/2045125320935306.

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As yet, no agents have been approved for the treatment of COVID-19, although several experimental drugs are being used off licence. These may have serious adverse effects and potential drug interactions with psychotropic agents. We reviewed the common agents being used across the world for the treatment of COVID-19 and investigated their drug interaction potential with psychotropic agents using several drug interaction databases and resources. A preliminary search identified the following drugs as being used to treat COVID-19 symptoms: atazanavir (ATV), azithromycin (AZI), chloroquine (CLQ)/hy

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Gustafsson, Maria, Per-Olof Sandman, Stig Karlsson, Yngve Gustafson, and Hugo Lövheim. "Association between behavioral and psychological symptoms and psychotropic drug use among old people with cognitive impairment living in geriatric care settings." International Psychogeriatrics 25, no. 9 (2013): 1415–23. http://dx.doi.org/10.1017/s1041610213000859.

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ABSTRACTBackground:Behavioral and psychological symptoms are common among cognitively impaired individuals and psychotropic drugs are widely used for their treatment. The aim of this study was to describe the prevalence and associated factors of psychotropic and anti-dementia drug use among old people with cognitive impairment living in geriatric care settings.Methods:The study comprised 2,019 cognitively impaired people living in geriatric care units in the county of Västerbotten, Sweden. Data concerning psychotropic and anti-dementia drug use, function in activities of daily living, cognitiv

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Baumann, P. "The AMSP-project: Pharmacovigilance in psychiatry - Presentation, challenges and results." European Psychiatry 29, S3 (2014): 663. http://dx.doi.org/10.1016/j.eurpsy.2014.09.050.

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For the introduction of novel drugs on the market, a limited number of patients have participated in clinical studies about their efficacy, safety and tolerance. However, many adverse effects and their impact are only revealed after the drug has been described in real life conditions, in comorbid and comedicated patients, in off-label situations or in populations not studied previously. Isolated severe adverse reactions have to be announced spontaneously by the physician to the authorities, but pharmacovigilance projects have the advantage of a more systematic approach. More than 25-years-ago,

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Eustace, Andrew, Elaine Murray, and Kelley Daly. "341 The Prevalence and Factors Associated with Anti-psychotic Prescribing on Admission to a Dementia Specific Nursing Home." Age and Ageing 48, Supplement_3 (2019): iii17—iii65. http://dx.doi.org/10.1093/ageing/afz103.223.

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Abstract Background The use of psychotropic medications and their adverse effects in frail adults has been debated extensively. However, it is unclear if antipsychotics are initiated in a nursing home or if the new resident arrives with the medication prescribed. The purpose of this study is to ascertain how many residents arrive already on antipsychotics and which factors, make them more likely to be on this medication. Methods All admission notes to the centre between 1st Jan 2018 and 31st Dec 2018 were reviewed. Inclusion criteria was any person admitted with a diagnosis of dementia. Exclus

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Gupta, Sumeet, Udayan Khastgir, Ogba Onwuchekwa, and Ioana Varvari. "Monitoring the Adverse Effects of Psychotropic drugs – Need for An Evidence-Based Approach." GLOBAL PSYCHIATRY ARCHIVES 5, no. 1 (2022): 51–63. http://dx.doi.org/10.52095/gpa.2022.4362.1034.

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Verdoux, H. "Safety of psychotropic medicines: contribution from observational evidence." Epidemiology and Psychiatric Sciences 27, no. 6 (2018): 531–36. http://dx.doi.org/10.1017/s2045796018000276.

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The risks associated with psychotropic drugs use should be accurately documented at the population level in view of the growing number of persons exposed to these drugs. The strengths of observational studies regarding the identification of drug-related harms mirror the limitations of randomised controlled trials and vice-versa. Observational studies can be carried out in large samples of unselected participants treated in real-life conditions and who may be followed up over long periods. Serious adverse effects undetected during pre-marketing clinical trials may be observed only in post-marke

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Freitas, Eliane Da Silva, Joaquim Alves Diniz, Natália Rodrigues Alves, Pedro Ivo Palacio Leite, Modesto Leite Rolim Neto, and Poliana Moreira Medeiros de Carvalho. "Benzodiazepines use in elderly patients attended at a Public Pharmacy in Pernambuco Brazil." Amadeus International Multidisciplinary Journal 4, no. 7 (2019): 203–16. http://dx.doi.org/10.14295/aimj.v4i7.91.

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: The elderly people are the group that most use psychotropic drugs, due to psychiatric comorbidity and somatic conditions. In Brazil some benzodiazepines are part of the National List of Essential Medicines (RENAME) being distributed free of charge, facilitating the population access, which can lead to irrational use. Methods: Cross-sectional, descriptive research through a qualitative and quantitative study of benzodiazepine use in patients attended at the Cedro Basic Pharmacy in the city of Cedro-PE. The data collection was done with the application of a semi-structured questionnaire. The p

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Kumari, Rani, Rachna Gupta, Manjeet Singh Bhatia, and Suresh Kumar Gupta. "Assessment of adverse drug reactions of psychopharmacological drugs in patients of psychiatric disorders." Journal of Pharmacovigilance and Drug Research 2, no. 2 (2021): 27–32. http://dx.doi.org/10.53411/jpadr.2021.2.2.6.

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Introduction: Psychopharmacological drugs are used in the treatment of different types of psychotropic disorders. These drugs are associated with a variety of adverse drug reactions (ADRs). The ADRs due to psychopharmacological drugs are a significant cause of mortality and morbidity. Objectives: The current study assessed the adverse drug reactions of psychopharmacological drugs in patients with psychiatric disorders. Methods: This study was a retrospective study. All ADR forms related to psychopharmacological drugs that were reported to the pharmacovigilance center, UCMS, and GTB

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Kumari, Rani, Rachna Gupta, Manjeet Singh Bhatia, and Suresh Kumar Gupta. "Assessment of Adverse Drug Reactions of Psychopharmacological Drugs in Patients of Psychiatric Disorders." Journal of Pharmacovigilance and Drug Research 2, no. 2 (2021): 23–27. https://doi.org/10.5281/zenodo.4904198.

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<strong>Abstract</strong> Psychopharmacological drugs are used in the treatment of different types of psychotropic disorders. These drugs are associated with a variety of adverse drug reactions (ADRs). The ADRs due to psychopharmacological drugs are a significant cause of mortality and morbidity. The current study assessed the adverse drug reactions of psychopharmacological drugs in patients with psychiatric disorders. This study was a retrospective study. All ADR forms related to psychopharmacological drugs that were reported to the pharmacovigilance center, UCMS, and GTB Hospital,&

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Bingefors, Kerstin, Dag Isacson, Lars Von Knorring, Björn Smedby, Lisa Ekselius, and Lawrence L. Kupper. "Antidepressant-treated Patients in Ambulatory Care." British Journal of Psychiatry 168, no. 3 (1996): 292–98. http://dx.doi.org/10.1192/bjp.168.3.292.

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BackgroundDespite the problems involved in treating depression and concomitant medical disease, there are virtually no longitudinal studies on drug utilisation among depressed patients.MethodUse of prescription drugs among all first-time users of antidepressants in a defined population five years before and six years after the index (first) treatment was compared to a referent group without antidepressant treatment. The generalised estimating equations (GEE) method was used for analysis.ResultsThe antidepressant-treated group used considerably more non-psychotropic drugs during the whole study

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Ferreira, A. R., S. Martins, C. Dias, M. R. Simões, and L. Fernandes. "Psychotropic Use in Elderly with Cognitive Impairment Living in Nursing Homes." European Psychiatry 41, S1 (2017): S174. http://dx.doi.org/10.1016/j.eurpsy.2017.01.2069.

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IntroductionElderly patients in nursing homes (NH) are often prescribed medications for many physical and mental health problems, with polypharmacy. There is a considerable number of studies documenting this extensive prescription of psychotropic medication, despite the raised concerns about their overuse/misuse, due to serious adverse effects, including increased rate of cognitive decline associated with antipsychotics.AimsTo characterize the prescription of psychotropics in elderly sample with cognitive impairment living in NH.MethodsElderly living in three Portuguese NH were included in thi

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Blom, Johanna, Elena Barisone, Marina Bertolotti, et al. "The Use of Psychotropic Medication in Pediatric Oncology for Acute Psychological and Psychiatric Problems: Balancing Risks and Benefits." Children 9, no. 12 (2022): 1878. http://dx.doi.org/10.3390/children9121878.

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Severe acute behavioral and emotional problems represent one of the most serious treatment-related adverse effects for children and adolescents who have cancer. The critical and severe nature of these symptoms often makes necessary the use of psychotropic drugs. A working group composed of experts in multiple disciplines had the task of creating an agreement regarding a management plan for severe acute behavioral and emotional problems (SABEPs) in children and adolescents treated for cancer. To obtain global information on the use of psychotropic drugs in pediatric oncology, the working group

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Kocharyan, Garnik. "Hypoactive Sexual Desire and Other Sexual Dysfunctions Caused by Psychotropic Drugs and Anticonvulsants." Health of Man, no. 1 (March 31, 2023): 34–42. https://doi.org/10.30841/2307-5090.1.2023.280049.

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Currently, there are a huge number of drugs. Every year their number increases and their number is in the tens of thousands, which makes it possible to speak of a “pharmaceutical explosion”. In addition to its main therapeutic effect, each of the drugs has side effects, which, in particular, may affect the sexual sphere. This article discusses the literature on the side effects of psychotropic drugs and anticonvulsants, which can lead to hypoactive sexual desire and other sexual dysfunctions. The side effects on sexual functions of tranquilizers, antipsychotics (traditional and new

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Kennedy, Craig H., and Kim A. Meyer. "The Use of Psychotropic Medication for People with Severe Disabilities and Challenging Behavior: Current Status and Future Directions." Journal of the Association for Persons with Severe Handicaps 23, no. 2 (1998): 83–97. http://dx.doi.org/10.2511/rpsd.23.2.83.

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People with severe disabilities who engage in challenging behavior are often prescribed psychotropic medication as a form of intervention. Although the goal of the medication is to reduce challenging behavior, limited empirical evidence is available to support the use of psychotropic intervention for people with severe disabilities. However, across a range of drug classes basic research suggests that many psychotropic medications selectively affect dimensions of behavior that could be of benefit in reducing challenging behavior. Currently, researchers cannot demonstrate whether most drugs pres

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Tataru, Alexandra, George Tătaru, Floris Petru Iliuță, et al. "The interactions between psychotropic medication and drugs used in the treatment of cardiovascular diseases." Bulletin of Integrative Psychiatry 101, no. 2 (2024): 67–76. http://dx.doi.org/10.36219/bpi.2024.2.07.

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The coexistence of psychiatric disorders and cardiovascular diseases represents a complex clinical challenge, often necessitating the concurrent use of medications from both therapeutic categories. While these medications are essential for managing their respective pathologies, their combined use can lead to interactions that may affect treatment outcomes and patient safety. Understanding the interactions between psychotropic drugs and those used in cardiovascular diseases is crucial for healthcare professionals to optimize therapeutic regimens and minimize potential adverse effects. This arti

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Ford, Loretta T., and Jonathan D. Berg. "Analytical evidence to show letters impregnated with novel psychoactive substances are a means of getting drugs to inmates within the UK prison service." Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 55, no. 6 (2018): 673–78. http://dx.doi.org/10.1177/0004563218767462.

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Introduction Novel psychotropic substances also known as legal highs are a major concern in UK prisons, fuelling violence and putting a strain on resources for inmates requiring medical treatment for adverse effects. We provide a clinical toxicology service including routine screening for novel psychoactive substances. In 2015, we were approached by Her Majesty Prison Service search dog training team to advise on which novel psychoactive substances to target, and again in 2016 to further provide analytical support to test five letters which the dogs positively identified for novel psychotropic

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Halaris, Angelos. "Antidepressant Drug Therapy in the Elderly: Enhancing Safety and Compliance." International Journal of Psychiatry in Medicine 16, no. 1 (1987): 1–19. http://dx.doi.org/10.2190/uhl6-0x4w-frng-8pff.

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This review article addresses some of the complex issues surrounding antidepressant drug usage among elderly depressives. While primarily geared toward the psychiatrist in general practice, the article provides useful information for the nonpsychiatric physician who is frequently called upon to evaluate and treat affective disorders in the geriatric population. Since tricyclic antidepressants and lithium are the most commonly used psychotropic drugs in the treatment of depression, their side effects and adverse reactions are discussed specifically as these relate to the elderly. Suggestions ar

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Lozzi, Flavia, Cosimo Di Raimondo, Caterina Lanna, et al. "Latest Evidence Regarding the Effects of Photosensitive Drugs on the Skin: Pathogenetic Mechanisms and Clinical Manifestations." Pharmaceutics 12, no. 11 (2020): 1104. http://dx.doi.org/10.3390/pharmaceutics12111104.

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Photosensitivity induced by drugs is a widely experienced problem, concerning both molecule design and clinical practice. Indeed, photo-induced cutaneous eruptions represent one of the most common drug adverse events and are frequently an important issue to consider in the therapeutic management of patients. Phototoxicity and photoallergy are the two different pathogenic mechanisms involved in photosensitization. Related cutaneous manifestations are heterogeneous, depending on the culprit drug and subject susceptibility. Here we report an updated review of the literature with respect to pathog

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Baumann, P. "JS01-01 - Pharmacokinetics of psychotropic drugs - keys for treatments’ improvements." European Psychiatry 26, S2 (2011): 1995. http://dx.doi.org/10.1016/s0924-9338(11)73698-7.

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Non-response, adverse effects and pharmacokinetic interactions with clinical consequences are frequent manifestations observed in psychiatric patients treated with psychotropic drugs. These risks are increased in patients belonging to the category of “special populations”: elderly patients, children and adolescents, patients with a genetic particularity of metabolism or suffering from somatic or psychic comorbidities. Increasingly, the use of generics has been shown to represent a source of unexpected treatment outcomes. Therapeutic drug monitoring (TDM) is not only recommended in these situat

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