Academic literature on the topic 'Pteridine Pteridine'

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Journal articles on the topic "Pteridine Pteridine"

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Mclntyre, G. S., and R. H. Gooding. "Variation in the pteridine content in the heads of tsetse flies (Diptera: Glossinidae: Glossina Wiedemann): evidence for genetic control." Canadian Journal of Zoology 74, no. 4 (1996): 621–26. http://dx.doi.org/10.1139/z96-071.

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The pteridine content of the head capsule of teneral flies from 11 genetically selected lines (including eye-color mutants) of Glossina morsitans morsitans Westwood and Glossina palpalis palpalis Robineau-Desvoidy was examined using fluorescence spectroscopy. Wild-type G. p. palpalis had a greater pteridine content than did wild-type G. m. morsitans. Within G. m. morsitans there was a 25% variation in fluorescence values between genetic lines. Wild-type G. p. palpalis had the same pteridine content as brick mutants but more than tan mutants; in G. m. morsitans the salmon mutants had a higher p
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Burton, Casey, and Yinfa Ma. "The role of urinary pteridines as disease biomarkers." Pteridines 28, no. 1 (2017): 1–21. http://dx.doi.org/10.1515/pterid-2016-0013.

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AbstractPteridines and their derivatives function as intermediates in the metabolism of several vitamins and cofactors, and their relevance to disease has inspired new efforts to study their roles as disease biomarkers. Recent analytical advances, such as the emergence of sensitive mass spectrometry techniques, new workflows for measuring pteridine derivatives in their native oxidation states and increased multiplexing capacities for the simultaneous determination of many pteridine derivatives, have enabled researchers to explore the roles of urinary pteridines as disease biomarkers at much lo
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Goldberg, M., F. Gassner, and M. Merkenschlager. "Studies and Comparison of Urinary Pteridine Patterns in Dogs and Cats and their Alteration in Various Neoplasias and Virus Infections." Pteridines 1, no. 1 (1989): 29–35. http://dx.doi.org/10.1515/pteridines.1989.1.1.29.

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Summary Urinary excretion levels of five pteridines in healthy cats and dogs and in 14 groups of animals with tumours or virus infections were determined by HPLC after partial purification by ion exchange chromatography. Healthy cats and dogs produce species specific differences. In contrary to cats 6-hydroxymethylpterin was not detectable in dogs. Whereas in dogs biopterin presents the main part of pteridines (about 70%), cats contain about 53% catabolic isoxanthopterin in the pteridine pattern. In the various tumours no qualitative but quantitative alterations in the pteridine concentrations
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Girgin, Gözde, Terken Baydar, Dietmar Fuchs, Gönül Sahin, Elif Özmert, and Kadriye Yurdakök. "Evaluation of Serum and Urinary Levels of some Pteridine Pathway Components in Healthy Turkish Children." Pteridines 23, no. 1 (2012): 90–95. http://dx.doi.org/10.1515/pteridines.2012.23.1.90.

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Abstract Neopterin, as a non-conjugated pteridine, is synthesized from guanosine triphosphate and its production is upregulated upon the activation of cellular immune response. Alterations of pteridines in body fluids are known to correlate well with existing diseases and stages, prognosis, clinical outcomes and survival data. It is of advantage to have a pteridine database of healthy volunteers to determine normal values. Thereby, especially in children there is no detailed study on pteridine levels. The aim of this study is to initiate the establishment of pteridine database of healthy child
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Soyka, Rainer, and Wolfgang Pfleiderer. "Pteridines, XCVI. Synthesis and Reactions of 6-(1,2,3-Trihydroxypropyl)pteridines." Pteridines 2, no. 2 (1990): 63–74. http://dx.doi.org/10.1515/pteridines.1990.2.2.63.

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Summary Various hydropyrano [3.2-g] pteridines (7, 10, 12, 21 , 33) were oxidized to the corresponding 6-(1,2,3- trihydroxypropyl)pteridine derivatives (8,9, 11, 13,32, 34), which are valuable intermediates for the synthesis of new 6-substituted pteridines (15 - 46). Periodate oxidation led to pteridine-6-carboxaldehydes (15, 16, 17, 38), which easily formed oximes (19 - 22, 39, 40). The aldehydes were further oxidized to 6-carboxylic acids (25,26,42) or reduced to 6-hydroxymethyl derivatives (27, 28, 43). Reductive condensations of the aldehydes (15, 16, 38) with p-aminobenzoylglutamic acid a
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Rinkevich, Frank D., Joseph W. Margotta, Jean M. Pittman, James A. Ottea, and Kristen B. Healy. "Pteridine levels and head weights are correlated with age and colony task in the honey bee,Apis mellifera." PeerJ 4 (June 30, 2016): e2155. http://dx.doi.org/10.7717/peerj.2155.

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Background.The age of an insect strongly influences many aspects of behavior and reproduction. The interaction of age and behavior is epitomized in the temporal polyethism of honey bees in which young adult bees perform nurse and maintenance duties within the colony, while older bees forage for nectar and pollen. Task transition is dynamic and driven by colony needs. However, an abundance of precocious foragers or overage nurses may have detrimental effects on the colony. Additionally, honey bee age affects insecticide sensitivity. Therefore, determining the age of a set of individual honey be
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Döring, Thomas, Romesh C. Boruah, and Wolfgang Pfleiderer. "Synthesis of 7-Acyl-2,4-disubstituted Pteridines by Radical Nucleophilic Substitution and Displacement Reactions." Pteridines 15, no. 4 (2004): 129–48. http://dx.doi.org/10.1515/pteridines.2004.15.4.129.

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Abstract 2,4-Disubstituted pteridine derivatives (1-3) react with acyl radicals very selectively in position 7 by a nucleophilic Substitution mechanism (4-10). Oxidation of the 2-methylthio group proceeds with m-chloroperbenzoic acid in good yields to the corresponding 7-acyl-2-methylsulfonyl-4-aminopteridines (11-16). The methylsulfonyl group can easily been displaced by nucleophiles such as aliphatic amines (27, 29, 32-42, 45), cyclic amines (56-61), aromatic amines (30, 31) and amino acids (43-54). Oxygen nucleophiles lead to 7-acyl-isopterin derivatives (62-66). The acyl side-chain is also
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Edalat, Hamideh, Mohammad Akhoundi, and Hamidreza Basseri. "Age-dependance of pteridines in the malaria vector, Anopheles stephensi." Pteridines 28, no. 3-4 (2017): 157–61. http://dx.doi.org/10.1515/pterid-2017-0009.

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AbstractDetermining the accurate age of malaria vectors is crucial to measure the risk of malaria transmission. A group of fluorescent chemicals derived from a pyrimidine-pyrazine ring structure known as pteridines from the head, thorax and whole body of adult female Anopheles stephensi were identified and evaluated as a tool for chronological and physiological age determination of malaria vectors. The female mosquitoes were collected from an insectary colony at an interval of every 5 days, up to 30 days, and the pteridines of head, thorax and whole body were detected fluorometrically by high-
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Tsusué, M., S. Kuroda, and H. Sawada. "Localization of Sepiapterin Deaminase and Pteridines In the Granules In Epidermal Cells of the Silkworm, Bombyx mori." Pteridines 2, no. 3 (1990): 175–82. http://dx.doi.org/10.1515/pteridines.1990.2.3.175.

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Summary A new method for assay of sepiapterin deaminase (3.5.4.24) activity by use of high performance liquid chromatography (HPLC) was developed. By this sensitive method the enzyme activity in the cell organelle was assayed. After cell fractionation, the enzyme was extracted with deoxycholate from pteridine granules of epidermal cells of the lemon mutant silkworm. On stepwise sucrose gradient centrifugation, most of the enzyme activity localized in the aggregated pteridine granules fraction, while the soluble fraction contained only one fourth of the total enzyme activity. The enzyme in the
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Ochoa, C., M. Rodríguez, L. Domínguez, et al. "Nematocide activity of 6,7-diarylpteridines in three experimental models." Journal of Helminthology 73, no. 4 (1999): 333–36. http://dx.doi.org/10.1017/s0022149x99000554.

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Thein vitronematocide activity of seventeen 6,7-diarylpteridines has been tested using three different experimental models,Caenorhabditis elegans,Nippostrongylus brasiliensisandHeligmosomoides polygyrus. The method of evaluation of inhibition in the secretion of acetylcholinesterase byH. polygyrusseems to be the most indicated to avoid false positives. Thein vivoactivities, againstTrichinella spiralis, of the mostin vitroactive pteridines have been assayed. All pteridine derivatives bearing 6,7-di-p-bromophenyl substituents have shownin vitronematocide activites in the three experimental model
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Dissertations / Theses on the topic "Pteridine Pteridine"

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Rebelo, Jorge Manuel Baeta Simões. "Biosynthesis and function of biological pteridines structural studies on two molybdopterin containing aldehyde oxido-reductases, from Desulfovibrio desulfuricans ATCC 27774 and from Desulfovibrio gigas, and the GTP cyclohydrolase I on E. coli, responsible for the first step of the tetrahydropterin biosynthesis /." [S.l. : s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=972340319.

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Guschin, Dmitrii. "Chemische Modifizierung von Pyranopterinen und deren Metallkomplexe strukturelle Modelle für Zentren in Metalloenzymen /." [S.l.] : [s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=967843537.

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Ekwall, Olov. "Pteridine dependent hydroxylases as autoantigens in autoimmune polyendocrine syndrome type 1." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2001. http://publications.uu.se/theses/91-554-4941-7/.

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Chatelet, Pascal. "Ptéridines non conjuguées et infections neuro-méningées." Lille 2, 1990. http://www.theses.fr/1990LIL2M349.

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Graham, Gordon W. "A study of biochemical genetic abnormalities associated with purine and pteridine metabolism." Thesis, University of Glasgow, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.301808.

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Barrack, Keri L. "Structural examination of trypanosomatid tubulin-binding cofactors and pteridine reductase 1 inhibition." Thesis, University of Dundee, 2013. https://discovery.dundee.ac.uk/en/studentTheses/73141a09-d8c2-4410-8884-3b3d80d1be00.

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Trypanosomatid parasites are the causative agents of neglected tropical diseases for which current therapies are inadequate. As primitive eukaryotic organisms, they also represent a useful model system to investigate fundamental cellular biology while studies of potential drug targets endeavour to develop new drug molecules. Aspects of both of these areas are explored in this thesis. Microtubules are polymers of tubulin and are essential in eukaryotes for cell division, motility and maintenance of cell morphology. Five tubulin-binding cofactors (TBC, named A-E) are proteins implicated in the f
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Luba, James. "Studies of Leishmania major Pteridine Reductase 1, a Novel Short Chain Dehydrogenase." eScholarship@UMMS, 1997. https://escholarship.umassmed.edu/gsbs_diss/45.

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Pteridine reductase 1 (PTR1) is an NADPH dependent reductase that catalyzes the reduction of several pterins and folates. The gene encoding this enzyme was originally identified in Leishmania based on its ability to provide resistance to the drug methotrexate (MTX). The DNA and amino acid sequences are known, and overproducing strains of Escherichia coli are available. PTR1 has been previously shown to be required for the salvage of oxidized pteridines (folate, biopterin, and others). Since Leishmaniaare folate and pterin auxotrophes, PTR1 is a possible target for novel anti-folate drugs for t
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Morin, Eric. "La néoptérine : aspects analytiques et physio-pathologiques." Paris 5, 1995. http://www.theses.fr/1995PA05P038.

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Vargas, Lowman Aidamalia. "Les bases génétiques de la pigmentation dans les embryons de punaise d'eau." Thesis, Lyon, 2019. http://www.theses.fr/2019LYSEN042/document.

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Le but de ce doctorat était de comprendre les bases génétiques de la diversification de la pigmentation extra-oculaire chez les embryons des Gerromorphes. La plupart des punaises semi-aquatiques présentent une variabilité de pattern de couleur jaune ou/et rouge dans les pattes et les antennes au stade embryonnaire. La couleur rouge observée dans les appendices étant similaire à celle présente dans les yeux, nous avons émis l'hypothèse que les couleurs extra-oculaires pouvaient être produites par la co-option des voies de synthèse des pigments des yeux. Nous avons d'abord déterminé l'histoire é
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Martini, Viviane Paula. "DETERMINAÇÃO E ESTUDOS DE ESTRUTURAS DE COMPLEXOS ENZIMALIGANTES RELEVANTES À BIOLOGIA DAS PTERIDINAS EM PARASITAS: BASE PARA O DESENVOLVIMENTO RACIONAL DE DROGAS TERAPÊUTICAS CONTRA DOENÇA DO SONO." UNIVERSIDADE ESTADUAL DE PONTA GROSSA, 2007. http://tede2.uepg.br/jspui/handle/prefix/2124.

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Made available in DSpace on 2017-07-24T19:38:12Z (GMT). No. of bitstreams: 1 VivianePaula.pdf: 3188050 bytes, checksum: 1b1ca9983470b6e6a3669cfd52a8c846 (MD5) Previous issue date: 2007-03-06<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>The enzymes dihydrofolate reductase-thymidylate synthase (DHFR-TS) and pteridine reductase (PTR) are involved in the pterin/folate dependent metabolism; together they represent an important target for chemotherapy of parasitic leishmanias and trypanosomes. Xray crystallography was used to elucidate accurately the structure of the PTR1 enzy
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Books on the topic "Pteridine Pteridine"

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Mohr, Detlef. Synthese, Reaktionen, und Eigenschaften neuer 6- und 7- subtituierter C-S- und C-C- verknüpfter Pteridine: Modellreaktionen für Naturstoffsyntesen. Hartung-Gorre, 1991.

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Brown, D. J. Pteridines. Wiley, 1988.

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Soyka, Rainer. Darstellung und Reaktionen von 6-(Trihydroxypropyl)-5,6-dihydro-pteridinen und 6-Formyl-pteridinen, sowie C-C-Verknüpfungsreaktionen an 6-substituierten 1,3-Dimethyllumazinen. Hartung-Gorre, 1987.

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Leskopf, Werner. Beiträge zur Synthese und Chemie von Acyllumazinen. Hartung-Gorre, 1987.

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Wiesenfeldt, Matthias. Synthese, Struktur und Eigenschaften neuer Derivate des 1,3-Dimethyllumazins. Hartung-Gorre, 1987.

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Heizmann, Gerhard. Methanopterin, ein interessantes Coenzym methanogener Bakterien aus der Sicht der organischen Synthese. Hartung-Gorre, 1991.

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Kang, Yonghan. Synthese und Reaktivität von Acylpteridinen und Vorstufen zum Methanopterin. Hartung-Gorre, 1987.

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Döring, Thomas. Synthese biologisch interessanter 2.7-disubstituierter Acylpteridine. Hartung-Gorre, 1987.

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Milstien, Sheldon, Gregory Kapatos, Robert A. Levine, and Barry Shane, eds. Chemistry and Biology of Pteridines and Folates. Springer US, 2002. http://dx.doi.org/10.1007/978-1-4615-0945-5.

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Ayling, June E., M. Gopal Nair, and Charles M. Baugh, eds. Chemistry and Biology of Pteridines and Folates. Springer US, 1993. http://dx.doi.org/10.1007/978-1-4615-2960-6.

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Book chapters on the topic "Pteridine Pteridine"

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Schomburg, Dietmar, and Dörte Stephan. "Pteridine oxidase." In Enzyme Handbook. Springer Berlin Heidelberg, 1994. http://dx.doi.org/10.1007/978-3-642-57942-4_184.

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Hutchison, Dorris J., and Joseph H. Burchenal. "Studies on Pteridine Metabolism." In Ciba Foundation Symposium - Chemistry and Biology of Pteridines. John Wiley & Sons, Ltd., 2008. http://dx.doi.org/10.1002/9780470718919.ch27.

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Carbon, John A., Robert B. Garland, Dale R. Hoff, Charles F. Howell, William R. Sherman, and E. C. Taylor. "Recent Developments in Pteridine Synthesis." In Ciba Foundation Symposium - Chemistry and Biology of Pteridines. John Wiley & Sons, Ltd., 2008. http://dx.doi.org/10.1002/9780470718919.ch8.

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Chang, Chi-Feng, Tom Bray, Kottayil I. Varughese, and John M. Whiteley. "Comparative Properties of Three Pteridine Reductases." In Advances in Experimental Medicine and Biology. Springer US, 1999. http://dx.doi.org/10.1007/978-1-4615-4735-8_50.

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Werner, E. R., G. Werner-Felmayer, D. Fuchs, A. Hausen, G. Reibnegger, and H. Wachter. "Relationships Between Pteridine Synthesis and Tryptophan Degradation." In Advances in Experimental Medicine and Biology. Springer New York, 1991. http://dx.doi.org/10.1007/978-1-4684-5952-4_16.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of copper(II)-pteridine complex." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-53974-3_225.

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Werner, E. R., G. Werner-Felmayer, H. Wachter, and B. Mayer. "Biosynthesis of nitric oxide: Dependence on pteridine metabolism." In Reviews of Physiology, Biochemistry and Pharmacology. Springer Berlin Heidelberg, 1995. http://dx.doi.org/10.1007/bfb0048266.

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Sawada, Yoshitomo, Haruo Shintaku, Gen Isshiki, Yutaka Hase, Tsuneo Tsuruhara, and Toshiaki Oura. "PTERIDINE VALUES IN CEREBROSPINAL FLUID IN SICK CHILDREN." In February 23–March 2, 1985, St. Christoph, Arlberg, Austria, edited by Helmut Wachter, H. Ch Curtius, and W. Pfleiderer. De Gruyter, 1985. http://dx.doi.org/10.1515/9783110860566-056.

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Golderer, G., S. Leitner, C. Wild, P. Gröbner, E. R. Werner, and G. Werner-Felmayer. "Pteridine and Nitric Oxide Biosynthesis in Physarum Polycephalum." In Chemistry and Biology of Pteridines and Folates. Springer US, 2002. http://dx.doi.org/10.1007/978-1-4615-0945-5_37.

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Hyland, K., and L. A. Arnold. "Clinical Utility of Pteridine Measurement in Cerebrospinal Fluid." In Chemistry and Biology of Pteridines and Folates. Springer US, 2002. http://dx.doi.org/10.1007/978-1-4615-0945-5_55.

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Conference papers on the topic "Pteridine Pteridine"

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Herrmann Fabian, C., N. Sivakumar, and J. Schmidt Thomas. "In silico identification and in vitro evaluation of new flavonoid inhibitors of pteridine reductase I from Leishmania major (LmPTR1)." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608036.

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Li, Gao-fei, and Guang-dao Hu. "Reflectance Characteristics and Mechanism Analysis of Pteridium Revolutum in Lead-Zinc Mine Area." In 2010 International Conference on Multimedia Technology (ICMT). IEEE, 2010. http://dx.doi.org/10.1109/icmult.2010.5631198.

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Yizhu Peng, Hongyu Tang, Hailong Li, et al. "Effects of Net photosynthetic rate of pteridium aquilium on photosynthetic active radiation increasing progressively." In 2011 International Conference on Remote Sensing, Environment and Transportation Engineering (RSETE). IEEE, 2011. http://dx.doi.org/10.1109/rsete.2011.5964078.

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CHE, GANG. "Experimental Study on Optimized technological parameters of Preservation for freeze-drying of Pteridium Aquilinum." In The Proceedings of the 5th Asia-Pacific Drying Conference. World Scientific Publishing Company, 2007. http://dx.doi.org/10.1142/9789812771957_0114.

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