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1

Prof., Najma Patel* Dr. Mubashir Kolachi and Dr. Hussain bakhsh Korejo. "PERCUTANEOUS TRANSMITRAL COMMISSUROTOMY IN CHILDREN: INTERMEDIATE TERM RESULTS WITH SPECIAL REFERENCE TO PULMONARY HYPERTENSION." Indo American Journal of Pharmaceutical Sciences 04, no. 08 (2017): 2591–98. https://doi.org/10.5281/zenodo.853359.

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Objective: To know the long-term results of percutaneous transmitral commissurotomy (PTMC) and fate of pulmonary hypertension in children who have undergone PTMC. Material: During the last 11 years 138 children, aged 10.48 ± 2.24 years (range 3.5 -16) had PTMC. Indications were echocardiographic evidence of moderate to severe mitral stenosis (MS) plus pulmonary hypertension (PH) more than 50 mmHg and/or FC III-IV Result: Pre PTMC, mean pressure gradient (MPG) across the mitral valve (MV) was 18.6 mmHg ± 3.4 which decreased to 7.6 mmHg ± 2.21 .Mitral valve area (MVA) was 0.62 cm2 ± 0.12 which i
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2

Khan, Muhammad Ijaz, Muhammad Omer Hashmi, Subtain Ul Hassan Abid, Bahauddin Khan, Hamid Iqbal, and Fahmida Khatoon. "Mid-Term Clinical and Echocardiographic Outcomes of Percutaneous Transvenous Mitral Commissurotomy in Patients with Rheumatic Mitral Stenosis." Pakistan Journal of Medical and Health Sciences 17, no. 2 (2023): 793–95. http://dx.doi.org/10.53350/pjmhs2023172793.

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Introduction: Mitral stenosis is a condition characterized by the narrowing of the mitral valve, which regulates blood flow between the left atrium and left ventricle of the heart. Objectives: The main objective of the study is to find the mid-term clinical and echocardiographic outcomes of percutaneous transvenous mitral commissurotomy in patients with rheumatic mitral stenosis. Material and Methods: The present study was a retrospective observational study conducted at Ayub Teaching Hospital, Abbottabad. The study included a total of 70 patients who underwent percutaneous transvenous mitral
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3

Wahab, Muhammad Abdul, Syed Kashif ur Rahman, and Umer Shafiq. "EFFECT OF PERCUTANEOUS TRANSVENOUS MITRAL COMMISUROTOMY (PTMC) ON RIGHT VENTRICULAR FUNCTION." Pakistan Heart Journal 55, Supplement1 (2022): S13. http://dx.doi.org/10.47144/phj.v55isupplement1.2429.

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Objectives: Rheumatic heart disease causes significant morbidity and mortality among the cardiovascular diseases. Mitral stenosis (MS) is the commonest of all rheumatic heart disease. MVR was the definitive treatment for symptomatic mitral stenosis. But after the introduction of percutaneous transvenous mitral valve commissurotomy (PTMC), it is emerged as a safe and effective procedure for the treatment of symptomatic mitral stenosis. To determine the pre and post changes in right ventricular function among patients subjected to percutaneous mitral valve commissurotomy for mitral stenosis.&#x0
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4

Adhikari, Chandra Mani. "Percutaneous Transluminal Mitral Commisuriotomy for Mitral Stenosis in Shahid Gangalal National Heart Centre, Kathmandu, Nepal." Nepalese Heart Journal 13, no. 2 (2016): 15–17. http://dx.doi.org/10.3126/njh.v13i2.15557.

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Mitral stenosis (MS) is almost invariably the result of long term complication of rheumatic fever. Based upon the nature and severity of MS, patients can be managed with medical treatment, percutaneous transvenous mitral commissurotomy (PTMC) or surgery. PTMC is proven to be simple, effective and safe; it is considered as treatment of choice in the management of MS. In Shahid Gangalal National Heart Centre, PTMC service started in 2001. First PTMC in the centre was done on 14th April 2001. Till June2016, 6023 PTMCs were done in the centre. Multiple studies evaluated the safety and efficacy of
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5

DURRANI, T., H. NASIR, S. ASMA, I. HUSSAIN, S. AZIZ, and S. GUL. "PROCEDURAL SUCCESS AND IMMEDIATE POST-PROCEDURE COMPLICATIONS OF PERCUTANEOUS TRANSVENOUS MITRAL COMMISSUROTOMY IN PATIENTS WITH RHEUMATIC MITRAL STENOSIS AT A TERTIARY CARE CENTER." Biological and Clinical Sciences Research Journal 2023, no. 1 (2023): 254. http://dx.doi.org/10.54112/bcsrj.v2023i1.254.

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Percutaneous Transvenous Mitral Commissurotomy (PTMC) is a minimally invasive procedure for mitral stenosis. Successful PTMC is achieving a post-procedural mitral valve area (MVA) of ≥1.5 cm2 with echocardiographic mitral regurgitation of less than grade 3–4 post-PTMC. Objectives: The study’s main objective is to assess the Procedural success and Immediate post-procedure Complications like worsening pre-existing mild MR (1) or development of new mitral regurgitation (2) and embolic stroke after the percutaneous transvenous mitral commissurotomy. Methods: This study aimed to evaluate the proced
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6

Naeem Hameed and Shahid Abbas. "Reduction in pulmonary artery pressures on right heart cath after percutaneous transmitral commissurotomy." Professional Medical Journal 30, no. 03 (2023): 359–63. http://dx.doi.org/10.29309/tpmj/2023.30.03.7384.

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Objectives: To find out the reduction in pulmonary artery pressures on right heart Cath after percutaneous trans mitral commissurotomy. Study Design: Cross-sectional Observational study. Setting: Catheterization Lab Faisalabad Institute of Cardiology, Faisalabad. Period: April 2022 till October 2022. Material & Methods: After approval from hospital ethical committee 67 patients of severe mitral stenosis having pliable valve suitable for PTMC on TTE followed by TEE to exclude its contraindications and then finalized for PTMC procedure were enrolled in study after informed consent. PTMC was
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7

Islam, Samsul, Jawad Khan, and Yusuf Khan. "Balloon mitral valvuloplasty: a re-emerging technique enhanced with real-time, three-dimensional transoesophageal cardiac ultrasound/echocardiography (3D-TOE)." BMJ Case Reports 16, no. 2 (2023): e253123. http://dx.doi.org/10.1136/bcr-2022-253123.

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We describe the case of a woman in her 60s with mitral stenosis, rate-controlled atrial fibrillation and a history of childhood rheumatic fever. She successfully underwent elective percutaneous transvenous mitral commissurotomy (PTMC), also described as balloon mitral valvuloplasty, for severe, symptomatic mitral stenosis. This was completed via right femoral vein access, trans-septal puncture and commissural separation guided by real-time three-dimensional (3D) transoesophageal echocardiography under general anaesthesia.Balloon mitral valvuloplasty is being completed more frequently in the UK
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8

Shabeer, Hassan. "Study of Clinical Profile and In-Hospital Outcomes of Patients Undergoing Percutaneous Transvenous Mitral Commissurotomy." Biological and Clinical Sciences Research Journal 6, no. 5 (2025): 148–51. https://doi.org/10.54112/bcsrj.v6i5.1753.

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Percutaneous Transvenous Mitral Commissurotomy (PTMC) is the preferred treatment for patients with symptomatic severe rheumatic mitral stenosis and favorable valve morphology. It replicates the physiological mechanism of surgical commissurotomy with less invasiveness. Objective: This study aimed to assess the clinical profile and in-hospital outcomes of patients undergoing PTMC at a tertiary cardiac care center. Methods: A prospective observational study was conducted at the Armed Forces Institute of Cardiology, Rawalpindi, from July 1 to December 31, 2023. A total of 96 patients with severe r
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9

Saeed, Amir, Noor ul Haq, Bilal Mustafa, Muhammad Shahid, Fayaz Ahmed Memon, and Fida Muhammad. "Frequency of Acute Mitral Regurgitation in Post Percutaneous Transvenous Mitral Commissurotomy (PTMC) Patients with Severe Mitrall Stenosis (MS)." Pakistan Journal of Medical and Health Sciences 16, no. 4 (2022): 1171–73. http://dx.doi.org/10.53350/pjmhs221641171.

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Objective: The goal of this study is to see how often Acute Mitral Regurgitation is in patients with severe mitral stenosis who have undergone a percutaneous transvenous mitral commissurotomy (PTMC). Study Design: Cross-sectional study Pace and Duration: The study was carried out at cardiology department of Lady Reading Hospital MTI, Peshawar and PIMS hospital, Islamabad for the duration of six months from 16th August 2021 to 15th February 2021. Methods: A total of 85 patients of both genders that underwent percutaneous transvenous mitral commissurotomy (PTMC) were included in this study. A de
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10

Beg, Ahsan, Muhammad Younas, Amjad Mahmood, Mubashar Shervani, and Fakher e. Fayaz. "IMMEDIATE RESULTS OF PERCUTANEOUS TRANS-MITRAL COMMISSOROTOMY IN JUVENILE MITRAL STENOSIS." Pakistan Armed Forces Medical Journal 70, Suppl-4 (2021): S799–802. http://dx.doi.org/10.51253/pafmj.v70isuppl-4.6027.

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Objectives: Immediate result of PTMC in juvenile (5-12 years) rheumatic mitral stenosis.
 Study Design: Observational descriptive and retrospective study.
 Place and Duration of Study: Institute of Cardiology, Multan from 2009 to Jun 2020.
 Methodology: This is an observational descriptive and retrospective study carried out at Institute of Cardiology, Multan from 2009 to Jun 2020. Patients with clinical evidence of significant mitral stenosis were undergone transthoracic echocardiography. Mitral stenosis was defined as mitral valve area <1.0 cm2 . Mean mitral valve gradient
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11

Rafique, Muhammad, Abdul Salam, Fazal ur Rehman, Wajid Hussain, Waqar Azim, and Muhammad Hashim. "Effect of Percutaneous Transvenous Mitral Commissurotomy in Severe Mitral Stenosis: A Cross Sectional Study." International Journal of Current Research and Review 14, no. 08 (2022): 73–75. http://dx.doi.org/10.31782/ijcrr.2022.14813.

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Introduction: The inflow obstruction from the left atrium to the left ventricle due to rheumatic involvement of apparatus is the main cause of Mitral stenosis. The patients with mitral valve involvement are found to have a combination of stenosis and regurgitation. Due to the thromboembolic phenomenon, left atrial dilatation and stasis predispose thrombus formation. So, even after percutaneous treatment, the elevated pressure in MS patients causes morbidity and mortality. Aim: To assess the effect of percutaneous transvenous mitral commissurotomy (PTMC) in reducing pulmonary hypertension in pa
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12

Shrestha, Manish, Chandra Mani Adhikari, Urmila Shakya, Aayush Khanal, Shradha Shrestha, and Rajib Rajbhandari. "Percutaneous Transluminal Mitral Commissurotomy in Nepalese children with Rheumatic Mitral Stenosis." Nepalese Heart Journal 10, no. 1 (2014): 23–26. http://dx.doi.org/10.3126/njh.v10i1.9743.

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Background: Rheumatic heart disease is one of the most common heart diseases in developing country; however rheumatic mitral stenosis in children is relatively rare. Percutaneous transluminal mitral commissurotomy is a well established therapeutic intervention for mitral stenosis in adults. The study is conducted to determine the efficacy and safety of PTMC in children with severe mitral stenosis. Methods: A single centre retrospective study is conducted over a 3 and half years period (from 16th November, 2009 to 15th May, 2013) in Shahid Gangalal National Heart Centre, Kathmandu, Nepal. All c
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13

Rana, Muhammad Anjum Rana, Jalaludin Jalaludin, Syed Husnain Raza Bukhari Bukhari, Muhammad Suleman Khan Khan, Rizwan Ahmad Yaqoob Yaqoob, and Yasir Arfat Arfat. "Case Report: 3D TEE Guided Percutaneous Transvenous Mitral Commissurotomy (PTMC)." Journal of Cardiovascular Diseases 19, no. 3 (2024). http://dx.doi.org/10.55958/jcvd.v19i3.156.

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BACKGROUND: Rheumatic heart disease continues to be a major health burden in developing world. Mitral valvular stenosis is its most common sequalae. For most individuals with symptomatic mitral stenosis, (PTMC) remains the most viable option and the treatment of choice for patient with mitral stenosis.1 It carries risk of pericardial tamponade due to the inability to directly visualize the atrial spetum under fluoro guidance. Incorporation of easily available TEE modality can make it highly safe due to capability of performing the septal puncture under direct visualization. CASE PRESENTATION:
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14

Mahjoob, Mohammad Parsa, Roxana Sadeghi, Mohammad Haji Aghajani, et al. "The Effect of Balloon Mitral Valvuplasty on BNP Plasma Level in Mitral Stenosis." International Journal of Cardiovascular Practice In Press, In Press (2023). http://dx.doi.org/10.5812/intjcardiovascpract-131154.

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Background: Mitral valve stenosis (MS), which could be progressive, is one of the most important valvular disorders in developing countries. Percutaneous transvenous mitral commissurotomy (PTMC) is a well-accepted treatment option for dealing with symptomatic MS. Brain natriuretic peptide (BNP) has been used as a prognostic marker for clinical outcomes in patients with heart failure and acute coronary syndrome routinely. Objectives: This study aimed to determine the relationship between BNP levels and hemodynamic parameters in patients with MS who underwent PTMC. Methods: In this case-control
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15

Ali, Nauman, Muhammad Shahid, Kashif Ali Hashmi, and Shoaib Abid. "EFFECTIVENESS OF PERCUTANEOUS TRANSVENOUS MITRAL COMMISSUROTOMY (PTMC) IN REDUCING PULMONARY HYPERTENSION IN PATIENTS WITH SEVERE MITRAL STENOSIS." Pakistan Heart Journal 53, no. 4 (2021). http://dx.doi.org/10.47144/phj.v53i4.1818.

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Objective: The objective of our study was to assess the reduction in severe pulmonary hypertension after PTMC in patients of severe mitral stenosis. Methodology: One hundred twenty-four patients of severe mitral stenosis with severely elevated pulmonary pressures more than 50 mmHg between 15 to 60 years of age of either gender undergoing elective PTMC at Chaudry Pervaiz Elahi Institute of Cardiology, Multan were included in this study. Post PTMC pulmonary pressures were noted 24 hours after PTMC. Results: Mean age of the patients was 35.45 ± 10.38 years. Diabetes mellitus was found to be prese
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16

Andishmand, Abbas, Hossein Montazer Ghaem, Somayeh Fallahzadeh, et al. "Mid-term results of percutaneous transmitral commissurotomy (PTMC) in central iran." Cardiovascular Biomedicine Journal, August 11, 2024. http://dx.doi.org/10.18502/cbj.v4i1.16221.

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Objectives: Percutaneous Trans-Mitral Commissurotomy (PTMC) is an effective non-surgical treatment in patients with severe rheumatic mitral valve stenosis. This study aimed to evaluate the mid-term results of this procedure in central Iran. Methods: This retrospective study was performed on 101 patients with severe mitral valve stenosis who underwent successful PTMC from March 2011 to September 2018 in Afshar Hospital in Yazd. At follow-up, all patients underwent clinical examination, two-dimensional and color Doppler echocardiography, and events were recorded. Data were analyzed using SPSS so
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17

Firouzi, Ata, Niloufar Samiei, Somayyeh Ahmadi, et al. "Percutaneous Transluminal Mitral Commissurotomy in Pregnant Women with Severe Mitral Stenosis." Journal of Tehran University Heart Center, April 17, 2019. http://dx.doi.org/10.18502/jthc.v14i1.650.

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Background: Mitral stenosis tends to worsen during pregnancy because of the increase in the cardiac output and the heart rate. In nonresponders to medical therapy, percutaneous transluminal mitral commissurotomy (PTMC) may be performed when there is a suitable valvular anatomy. In this study, we aimed to investigate the clinical and fetal outcomes of pregnant women with mitral stenosis who underwent PTMC.
 Methods: Thirty-one patients undergoing PTMC during pregnancy were enrolled in this study. The mitral valve area (MVA), the transmitral valve mean gradient (MVMG), and the severity of m
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18

Omar, AlFazir, Amin Ariff, Robaayah Zambahari, and Rosli Mohd Ali. "Abstract 20155: 15-year Outcomes and Predictors of Success for Percutaneous Mitral Commissurotomy for Rheumatic Mitral Stenosis." Circulation 130, suppl_2 (2014). http://dx.doi.org/10.1161/circ.130.suppl_2.20155.

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Background: Rheumatic heart disease remains the most common acquired heart disease in children, especially in developing countries. This study aims to investigate the predictors of immediate procedural success and the immediate and long-term outcomes in patients undergoing percutaneous mitral commissurotomy (PTMC). Methods: A total of 1552 patients with rheumatic mitral stenosis and underwent PTMC from 1989 to 2012 were identified. We divided the group according to Wilkins score as low risk (≤5), intermediate risk (6-8) and high-risk (≥9). Procedural success was defined as mitral valve area gr
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Abdallah, Hany Mostafa, Mohamed Hassan Mohamed, and Mina Murad Riad. "Comparison between Tadalafil and Tamsulosin in Reliving Stent Related Symptoms: A Randomised Study." QJM: An International Journal of Medicine 116, Supplement_1 (2023). http://dx.doi.org/10.1093/qjmed/hcad069.768.

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Background Ureteroscopy had been recognized as a major method for treating ureteric calculi. Although invasive, the development of smaller and more flexible ureteroscopes, and a new generation of various intracorporial lithotripters, has made this procedure safer and more effective. Placing a ureteric stent after ureteroscopy with stone extraction is done by some urologists routinely to prevent possible stenosis or to decrease secondary pain caused by mucosal oedema. Objective To evaluate and compare the efficacy and safety of Tadalafil and Tamsulosin in reliving Double-J stent-related symptom
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