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Journal articles on the topic 'Puberty'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Akyürek, Nesibe. "ERKEN PUBERTEYE YAKLAŞIM." Chronicles of Precision Medical Researchers 2, no. 3 (2022): 62–64. https://doi.org/10.5281/zenodo.5874695.

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<strong>Abstact</strong> Puberty is a physiological process if it occurs at the normal time and duration. Precocious puberty is defined as development of secondary sex characteristics before the age of 8 years in girls and before the age of 9 years in boys.The causes of puberty symptoms in patients presenting with early puberty findings should be investigated first.Apart from the fact that early puberty affects the final height, psychosocial disorders may develop due to inappropriate pubertal development. <strong>Key words: central precocious puberty,</strong> <strong>peripheral precocious pub

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Fitriani, Baiq Mesy Darita, Muhammad Ashari, Tahyah Hidjaz, and Lalu Wira Pribadi. "Pre-pubertal Growth of PE (Peranakan Ettawa) Goat and it’s Crosses with Boer Buck in Lombok Island, Indonesia." Jurnal Biologi Tropis 25, no. 2 (2025): 2311–21. https://doi.org/10.29303/jbt.v25i2.9443.

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The research which was designed to investigate the pre-pubertal growth performance of PE (Peranakan Ettawa) Goat and Boer >< PE crossbred kids under different birth type, was carried out by observing the weaning weight (BS90), weight at puberty (BB160) and pre-pubertal daily weight gain (PBBHpra-pubertas) of 43 Peranakan Ettawa (PE), 35 Boerawa Grade-1 (B.PE), 39 Boerawa Grade-2 (B2.PE), and 20 Boerawa Grade-3 (B3.PE) kids, each of which consists of single and twins birth type, determined purposively for the population of each genotype on 2 goat farms in Lombok Island. Data were obtained

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Dira, I. Komang Prayoga Ariguna, I. Made Arimbawa, and I. Made Darma Yuda. "Hubungan status nutrisi dengan gangguan pubertas pada remaja panti asuhan di Kota Denpasar." Intisari Sains Medis 14, no. 3 (2023): 1016–22. http://dx.doi.org/10.15562/ism.v14i3.1829.

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Background: Puberty is a transition period between childhood and adulthood influenced by various complex factors. Nutrition is one of the most important factors affecting pubertal development. Overweight or obese children are more likely to enter puberty earlier. Severe primary or secondary malnutrition can also delay the onset and progression of puberty. This study aims to determine the relationship between nutritional status and pubertal disorders in Denpasar city orphanage children. Methods: This study was conducted using an analytic research design with a cross-sectional design to determin

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Begum, Poly, Dipti Rani Saha, and Md Kamrul Hassan. "Precocious Puberty A Case Report." Bangladesh Journal of Obstetrics & Gynaecology 30, no. 2 (2016): 109–12. http://dx.doi.org/10.3329/bjog.v30i2.30906.

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The parents of a 04-year-old girl bring her to a Gynaecologist because of breast development, appearance of pubic hair and periodic per vaginal bleeding. Her medical history is unremarkable. The parents are of average height, and the mother reports first menstruating when she was 11 years old. At physical examination, the girl is 100 cm tall , weighs 17 kg, and has a bodymass index of 17. Her pubertal development is classified as Tanner stage 3 breast development and Tanner stage 2 pubic hair development. She was diagnosed as a case of precocious puberity. Appearance of secondary sexual develo

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Klump, K. L., K. M. Culbert, J. D. Slane, S. A. Burt, C. L. Sisk, and J. T. Nigg. "The effects of puberty on genetic risk for disordered eating: evidence for a sex difference." Psychological Medicine 42, no. 3 (2011): 627–37. http://dx.doi.org/10.1017/s0033291711001541.

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BackgroundDifferences in genetic influences on disordered eating are present across puberty in girls. Heritability is 0% before puberty, but over 50% during and after puberty. Emerging data suggest that these developmental differences may be due to pubertal increases in ovarian hormones. However, a critical piece of evidence is lacking, namely, knowledge of genetic influences on disordered eating across puberty in boys. Boys do not experience increases in ovarian hormones during puberty. Thus, if pubertal increases in genetic effects are present in boys, then factors in addition to ovarian hor

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Sánchez-Garrido, M. A., J. M. Castellano, F. Ruiz-Pino, et al. "Metabolic Programming of Puberty: Sexually Dimorphic Responses to Early Nutritional Challenges." Endocrinology 154, no. 9 (2013): 3387–400. http://dx.doi.org/10.1210/en.2012-2157.

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Body energy stores and metabolic cues influence the onset of puberty. However, the pubertal impact of early nutritional challenges has been only fragmentarily addressed. We evaluated here the consequences, in terms of pubertal timing and hormonal markers, of various nutritional manipulations during pre- or postnatal maturation in rats of both sexes. Males and females were submitted to gestational undernutrition (UNG) or peripubertal (SUB) subnutrition or were raised in large (LL; underfeeding) or small (SL; overfeeding) litters. In addition, groups of UNG, LL, and SL rats were fed on a high-fa

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Lindhardt Johansen, Marie, Casper P. Hagen, Mikkel G. Mieritz, et al. "Pubertal Progression and Reproductive Hormones in Healthy Girls With Transient Thelarche." Journal of Clinical Endocrinology & Metabolism 102, no. 3 (2016): 1001–8. http://dx.doi.org/10.1210/jc.2016-2871.

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Abstract Context: Detailed evaluation of pubertal progression in girls from longitudinal studies is sparse, and the phenomenon of transient thelarche (TT), defined as the appearance, regression, and subsequent reappearance of breast buds, in healthy girls remains undescribed. Objective: To describe TT in terms of pubertal progression, growth, genotypes, and reproductive hormones and to apply new puberty nomograms for breast stages, pubic hair, and menarche. Design: A prospective, longitudinal population-based study. Patients or Other Participants: Ninety-eight healthy Danish schoolchildren (Ca

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Muganwa, Kellen, Oliva Bazirete, Marie Chantal Uwimana, et al. "Adolescent awareness and experience of the pubertal changes: A qualitative study from Rwanda." PLOS One 20, no. 6 (2025): e0325502. https://doi.org/10.1371/journal.pone.0325502.

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Introduction The transition from puberty to adolescence involves significant body changes that manifest differently across young children. It is essential that adolescents become aware of these changes so that they can easily navigate puberty’s physical, emotional, and interpersonal changes safely in terms of sexual and reproductive health. In Rwanda, there remains a gap in literature on adolescents’ awareness and experiences of pubertal changes among school going adolescents; particularly among those enrolled as day students. This research was undertaken to explore the awareness and understan

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Manotas, María Carolina, Daniel Mauricio González, Camila Céspedes, Catalina Forero, and Adriana Patricia Rojas Moreno. "Genetic and Epigenetic Control of Puberty." Sexual Development 16, no. 1 (2021): 1–10. http://dx.doi.org/10.1159/000519039.

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Puberty is a complex transitional phase in which reproductive capacity is achieved. There is a very wide variation in the age range of the onset of puberty, which follows a familial, ethnic, and sex pattern. The hypothalamic-pituitary-gonadal axis and several genetic, environmental, and nutritional factors play an important role in the onset of and throughout puberty. Recently, there has been significant progress in identifying factors that affect normal pubertal timing. Different studies have identified single nucleotide polymorphisms (SNPs) that affect pubertal timing in both sexes and acros

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Manotas, María Carolina, Daniel Mauricio González, Camila Céspedes, Catalina Forero, and Adriana Patricia Rojas Moreno. "Genetic and Epigenetic Control of Puberty." Sexual Development 16, no. 1 (2021): 1–10. http://dx.doi.org/10.1159/000519039.

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Puberty is a complex transitional phase in which reproductive capacity is achieved. There is a very wide variation in the age range of the onset of puberty, which follows a familial, ethnic, and sex pattern. The hypothalamic-pituitary-gonadal axis and several genetic, environmental, and nutritional factors play an important role in the onset of and throughout puberty. Recently, there has been significant progress in identifying factors that affect normal pubertal timing. Different studies have identified single nucleotide polymorphisms (SNPs) that affect pubertal timing in both sexes and acros

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Xu, Lu, Ming Li, Jinhua Yin, et al. "Change of Body Composition and Adipokines and Their Relationship with Insulin Resistance across Pubertal Development in Obese and Nonobese Chinese Children: The BCAMS Study." International Journal of Endocrinology 2012 (2012): 1–10. http://dx.doi.org/10.1155/2012/389108.

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A transient increase in insulin resistance (IR) is a component of puberty. We investigated the impact of body composition and adipokines on IR during puberty in Chinese children. This study included 3223 schoolchildren aged 6–18 years. IR was calculated using homeostasis model assessment (HOMA-IR). We revealed that body mass index (BMI) and waist circumference increased gradually during puberty in both genders, while fat-mass percentage (FAT%) increased steadily only in girls. Change of leptin showed striking sexual dimorphisms: in girls leptin increased steadily during puberty, whereas in boy

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Vazquez, M. J., I. Velasco, and M. Tena-Sempere. "Novel mechanisms for the metabolic control of puberty: implications for pubertal alterations in early-onset obesity and malnutrition." Journal of Endocrinology 242, no. 2 (2019): R51—R65. http://dx.doi.org/10.1530/joe-19-0223.

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Puberty is driven by sophisticated neuroendocrine networks that timely activate the brain centers governing the reproductive axis. The timing of puberty is genetically determined; yet, puberty is also sensitive to numerous internal and external cues, among which metabolic/nutritional signals are especially prominent. Compelling epidemiological evidence suggests that alterations of the age of puberty are becoming more frequent; the underlying mechanisms remain largely unknown, but the escalating prevalence of obesity and other metabolic/feeding disorders is possibly a major contributing factor.

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Voordouw, Jasper J., Mirjam M. van Weissenbruch, and Henriette A. Delemarre-van de Waal. "Intrauterine Growth Retardation and Puberty in Girls." Twin Research 4, no. 5 (2001): 299–306. http://dx.doi.org/10.1375/twin.4.5.299.

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AbstractSome, albeit not all studies on the relationship between intrauterine growth retardation (IUGR) and female pubertal development have found an earlier and rapidly progressing puberty as well as concomitant disorders of related functional systems such as polycystic ovary syndrome and short stature. These pubertal changes are part of a growing list of IUGR-related diseases, which includes non-insulin dependent diabetes mellitus and coronary heart disease. A pulsatile release of gonadotropin releasing hormone is thought to be a conditio-sinne-qua-non for the initiation of puberty. In the a

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van der Steen, Manouk, Annemieke J. Lem, Danielle C. M. van der Kaay, and Anita C. S. Hokken-Koèelega. "Puberty and Pubertal Growth in GH-treated SGA Children: Effects of 2 Years of GnRHa Versus No GnRHa." Journal of Clinical Endocrinology & Metabolism 101, no. 5 (2016): 2005–12. http://dx.doi.org/10.1210/jc.2016-1317.

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Abstract Context: Most studies on puberty in children born small for gestational age (SGA) report height and age at onset of puberty. GH-treated SGA children with an adult height (AH) expectation below −2.5 SDS at onset of puberty can benefit from an additional 2 years of GnRH analog (GnRHa) treatment. There are no data on puberty and growth after discontinuation of GnRHa treatment in GH-treated SGA children. Objective: This study aimed to investigate the effects on puberty and pubertal growth of 2 years GnRHa vs no GnRHa in GH-treated SGA children. Methods: This was a GH trial involving 76 pr

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Jonsdottir-Lewis, Elfa, Amalia Feld, Ryan Ciarlo, Erica Denhoff, Henry A. Feldman, and Yee-Ming Chan. "Timing of Pubertal Onset in Girls and Boys With Constitutional Delay." Journal of Clinical Endocrinology & Metabolism 106, no. 9 (2021): e3693-e3703. http://dx.doi.org/10.1210/clinem/dgab270.

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Abstract Context The decision whether to treat a child with delayed puberty with sex steroids is primarily based on patient, family, and provider preference. Knowing when children with constitutional delay eventually enter puberty would inform this decision. Objective, Design, Setting, Participants, and Outcome Measures To estimate and compare rates of pubertal entry, we conducted a retrospective cohort study by reviewing medical records of children evaluated for delayed puberty at a large academic medical center between 2000 and 2015, extracting data on pubertal status for all clinical visits

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Kythreotis, Alexandros K., Marina Nicolaou, Eirini Mitsinga, Habib Daher, and Nicos Skordis. "The Interplay Between Body Weight and the Onset of Puberty." Children 12, no. 6 (2025): 679. https://doi.org/10.3390/children12060679.

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This overview explores the complex relationship between environmental factors, particularly obesity, and the timing of puberty, with a focus on how hormonal and genetic interactions are influenced by external conditions. Puberty (gonadarche) is characterised by the activation of the hypothalamic–pituitary–gonadal (HPG) axis. The onset and progression of puberty vary significantly among individuals, primarily due to genetic factors, with key genes like kisspeptin 1 (KISS1) and makorin ring finger protein 3 (MKRN3) playing a crucial role. Cohesively, this paper emphasises that environmental fact

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German, A., M. Shmoish, J. Belsky, and Z. Hochberg. "Outcomes of pubertal development in girls as a function of pubertal onset age." European Journal of Endocrinology 179, no. 5 (2018): 279–85. http://dx.doi.org/10.1530/eje-17-1025.

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Background The relationship between pubertal onset and tempo and pubertal growth is controversial. We hypothesized that the age at onset of girls’ puberty predicts pubertal tempo and the rate of pubertal progression. Methods We analyzed the data of 380 girls from the prospective Study of Early Child Care and Youth Development (SECCYD) who were recruited in the USA from 1991 to 2006 and followed from birth to age 15.5 years. We used the following indicators: thelarche age (Tanner stage B2), pubarche age (P2), menarche age (M), the age when breast (B5) and pubic hair (P5) became fully mature, pu

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Chan, Yee-Ming, Margaret F. Lippincott, Priscila Sales Barroso, et al. "Using Kisspeptin to Predict Pubertal Outcomes for Youth With Pubertal Delay." Journal of Clinical Endocrinology & Metabolism 105, no. 8 (2020): e2717-e2725. http://dx.doi.org/10.1210/clinem/dgaa162.

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Abstract Context The management of youth with delayed puberty is hampered by difficulty in predicting who will eventually progress through puberty and who will fail to attain adult reproductive endocrine function. The neuropeptide kisspeptin, which stimulates gonadotropin-releasing hormone (GnRH) release, can be used to probe the integrity of the reproductive endocrine axis. Objective We sought to determine whether responses to kisspeptin can predict outcomes for individuals with pubertal delay. Design, Setting, and Participants We conducted a longitudinal cohort study in an academic medical c

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Carpini, Stela, Annelise Barreto Carvalho, Gil Guerra-Júnior, Maria Tereza Matias Baptista, Sofia Helena Valente Lemos-Marini, and Andréa Trevas Maciel-Guerra. "Spontaneous puberty in girls with early diagnosis of Turner syndrome." Arquivos Brasileiros de Endocrinologia & Metabologia 56, no. 9 (2012): 653–57. http://dx.doi.org/10.1590/s0004-27302012000900009.

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OBJECTIVE: To verify if the frequency of spontaneous pubertal development among girls with Turner syndrome (TS) diagnosed in infancy and childhood is greater than that of patients diagnosed later. SUBJECTS AND METHODS: Thirty three girls aged < 10 years at the time of diagnosis were evaluated regarding pubertal development. The frequency of spontaneous puberty was compared with that of girls aged > 13 years diagnosed at the same service. RESULTS: Sixteen of 32 informative patients had signs of spontaneous puberty, a frequency greater than that of patients diagnosed later. In six patients

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Deeb, Asma, Mariette Akle, Abrar Al Zaabi, et al. "Maternal attitude towards delaying puberty in girls with and without a disability: a questionnaire-based study from the United Arab Emirates." BMJ Paediatrics Open 2, no. 1 (2018): e000306. http://dx.doi.org/10.1136/bmjpo-2018-000306.

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BackgroundParental anxiety about the impact of puberty/menses, particularly in girls with severe disability leads to seeking therapeutic pubertal suppression. We aim to explore maternal attitudes and reasons for seeking pubertal suppression.MethodsMothers of girls receiving gonadotropin -releasing hormone analogue therapy in Mafraq hospital, Abu Dhabi were enrolled in the study. A semistructured interview was conducted to ascertain possible reasons for delaying puberty. The study group was divided into girls with a disability with central precocious puberty (CPP) or normal puberty and girls wi

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K, Dao, A. Koné, Drago AA, et al. "Pubertal Delay Secondary to Hashimoto's Disease in the Hypothyroid Phase: About a Case in the Internal Medicine Department of the Gabriel Touré University Hospital in Bamako, Mali." Scholars Journal of Medical Case Reports 12, no. 06 (2024): 991–96. http://dx.doi.org/10.36347/sjmcr.2024.v12i06.003.

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Introduction: Pubertal delay is defined by the absence of development of secondary sexual characteristics beyond the age of 13 in girls or 14 years in boys. In children of puberty age, delayed puberty is common in long-standing, untreated hypothyroidism. We report a case of delayed puberty revealed by Hashimoto's disease in the hypothyroid phase diagnosed in the Internal Medicine department of the Gabriel Touré University Hospital in Bamako, Mali. Observation: This was a female patient, aged 20 years old, without any particular medico-surgical ATCD or notion of taking medication, who had consu

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Najafianpour, B. "The Sources of Pubertal Information and their Impact on Stress and Anxiety Among Adolescents." European Psychiatry 24, S1 (2009): 1. http://dx.doi.org/10.1016/s0924-9338(09)70769-2.

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Adolescence is known as a period of major hormonal, physical, and psychological changes. Stress and anxiety during adolescence are associated with different factors. The aim of this study is to investigate and examine the associations between stress and anxiety and different sources of information received by adolescent students regarding puberty, as well as evaluating the intensity and degree of puberty's stress and anxiety. Using a cross-sectional method, two groups of students belonging to two different economic family levels were chosen randomly. Spillberger's test for anxiety and stress w

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Guerriero, Kathryn A., Kim L. Keen, and Ei Terasawa. "Developmental Increase in Kisspeptin-54 Release in Vivo Is Independent of the Pubertal Increase in Estradiol in Female Rhesus Monkeys (Macaca mulatta)." Endocrinology 153, no. 4 (2012): 1887–97. http://dx.doi.org/10.1210/en.2011-1701.

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Kisspeptin (KP) signaling has been proposed as an important regulator in the mechanism of puberty. In this study, to determine the role of KP in puberty, we assessed the in vivo release pattern of KP-54 from the basal hypothalamus/stalk-median eminence in prepubertal and pubertal ovarian-intact female rhesus monkeys. We found that there was a developmental increase in mean KP-54 release, pulse frequency, and pulse amplitude, which is parallel to the developmental changes in GnRH release that we previously reported. Moreover, a nocturnal increase in KP-54 release becomes prominent after the ons

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Fidora, Irma, Silvia Adi Putri, and Ropika Ningsih. "Efektifitas Pemberian Paket Belajar Kesehatan Reproduksi Terhadap Kesiapan Remaja Aisyiyah Menghadapi Masa Pubertas." Jurnal Smart Keperawatan 7, no. 2 (2020): 77. http://dx.doi.org/10.34310/jskp.v7i2.377.

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Masa remaja adalah masa terjadinya perubahan fisik dan mental yang dikenal dengan pubertas. Menarch merupakan salah satu tanda bahwa mereka sudah memasuki masa pubertas. Remaja yang tinggal di panti asuhan cenderung memiliki pengalaman yang berbeda ketika menghadapi masa pubertas terutama menjelang menarch dibandingkan remaja yang tinggal bersama orang tua. Informasi yang diperoleh mengenai pubertas terbatas. Perubahan pada masa pubertas bisa menyebabkan kecemasan dan ketakutan. Pemberian paket belajar kesehatan perlu sebagai upaya meningkatkan kesiapan remaja menghadapi masa pubertas. Panti A

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Andersson, Anna-Maria, Anders Juul, Jørgen H. Petersen, Jørn Müller, Nigel P. Groome, and Niels E. Skakkebæk. "Serum Inhibin B in Healthy Pubertal and Adolescent Boys: Relation to Age, Stage of Puberty, and Follicle-Stimulating Hormone, Luteinizing Hormone, Testosterone, and Estradiol Levels1." Journal of Clinical Endocrinology & Metabolism 82, no. 12 (1997): 3976–81. http://dx.doi.org/10.1210/jcem.82.12.4449.

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Inhibin B levels were measured in serum from 400 healthy Danish prepubertal, pubertal, and adolescent males, aged 6–20 yr, in a cross-sectional study using a recently developed immunoassay that is specific for inhibin B, the physiologically important inhibin form in men. In addition, serum levels of FSH, LH, testosterone, and estradiol levels were measured. Serum levels of inhibin B, FSH, LH, testosterone, and estradiol all increased significantly between stages I and II of puberty. From stage II of puberty the inhibin B level was relatively constant, whereas the FSH level continued to increas

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Alves, Márcia, Margarida Bastos, Teresa Almeida Santos, and Francisco Carrilho. "Função Gonadal na Síndrome de Turner." Acta Médica Portuguesa 26, no. 6 (2013): 655. http://dx.doi.org/10.20344/amp.1316.

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Introduction: Turner syndrome is characterized by the absence, total or partial, of one X chromosome in females, being one of the most frequent chromosomal abnormalities. Diagnosis is made by karyotype. Turner syndrome manifestations include primary hypogonadism, before or after puberty (gonadal dysgenesis). The degree and extent of gonadal disfunction are variable.Objectives: We intended to assess clinical, karyotype, gonadal function and pelvic ultrasound characteristics in women with Turner syndrome.Material and Methods: Retrospective study of patients with Turner syndrome followed in Endoc

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Costanzo, Mariana, José Garcia-Feyling, Nora Saraco, et al. "Accelerated Pubertal Tempo in a 46,XY Aromatase-Deficient Patient." Hormone Research in Paediatrics 90, no. 4 (2018): 275–82. http://dx.doi.org/10.1159/000492128.

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Background: Aromatase deficiency is a rare autosomal recessive disorder. 46,XY-affected patients often remain undiagnosed until late puberty. Only 2 pediatric cases have been reported. Data on pubertal development in affected males are scarce. Aim: To report the clinical phenotype and hormonal studies of an aromatase-deficient boy during the prepubertal and early pubertal period. Results: The patient was the older brother of a 46,XX girl with aromatase deficiency. Molecular analysis revealed a previously reported homozygous mutation (Arg192Cys) in the CYP19A1 gene. Pubertal onset was at 9.8 ye

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Chu, L., M. C. Riddell, J. E. Schneiderman, B. W. McCrindle, and J. K. Hamilton. "The effect of puberty on fat oxidation rates during exercise in overweight and normal-weight girls." Journal of Applied Physiology 116, no. 1 (2014): 76–82. http://dx.doi.org/10.1152/japplphysiol.00888.2013.

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Excess weight is often associated with insulin resistance (IR) and may disrupt fat oxidation during exercise. This effect is further modified by puberty. While studies have shown that maximal fat oxidation rates (FOR) during exercise decrease with puberty in normal-weight (NW) and overweight (OW) boys, the effect of puberty in NW and OW girls is unclear. Thirty-three NW and OW girls ages 8–18 yr old completed a peak aerobic capacity test on a cycle ergometer. FOR were calculated during progressive submaximal exercise. Body composition and Tanner stage were determined. For each participant, a b

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Oelkers, Lea, Mandy Vogel, Agnes Kalenda, et al. "Socioeconomic Status Is Related to Pubertal Development in a German Cohort." Hormone Research in Paediatrics 93, no. 9-10 (2020): 548–57. http://dx.doi.org/10.1159/000513787.

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<b><i>Introduction:</i></b> Current health literature suggests that there has been a decline in the age of pubertal onset and that pubertal onset/duration of puberty may, besides weight status, be influenced by socioeconomic context. <b><i>Objective:</i></b> The goal of this study was to determine whether pubertal onset/duration and puberty-triggering hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH) vary according to socioeconomic status (SES). Moreover, we aimed to propose cutoff values of serum LH and FSH for predicting

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Cemeroglu, Ayse Pinar, Damlanur Kaval, and Ozan Ozcan. "Etiology of Increased Referrals for Evaluation of Early Puberty in a Tertiary Care Center in Turkey: True Precocious Puberty, Obesity, or Parental Anxiety and Lack of Knowledge?" Global Pediatric Health 8 (January 2021): 2333794X2110090. http://dx.doi.org/10.1177/2333794x211009096.

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There has been a global increase in pediatric endocrinology referrals for the concerns of early puberty. The objective of this study was to determine the reasons behind this increase. A retrospective cross-sectional study was designed to analyze the clinical characteristics of patients seen for the concerns of early puberty in pediatric endocrinology clinic of a tertiary care center (Study A). Additionally, a prospective questionnaire study was designed to assess the knowledge and concerns of the mothers regarding the timing of puberty in girls (Study B). In study A, of the 305 girls, 42.9% we

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Wei, Christina, and Elizabeth Clare Crowne. "Recent advances in the understanding and management of delayed puberty." Archives of Disease in Childhood 101, no. 5 (2015): 481–88. http://dx.doi.org/10.1136/archdischild-2014-307963.

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Delayed puberty, especially in boys, is a common presentation in paediatrics. Recent advances have improved our understanding of the neuroendocrine, genetic and environmental factors controlling pubertal development, and hence inform the pathophysiology of delayed puberty. The discovery of kisspeptin signalling through its receptor identified neuroendocrine mechanisms controlling the gonadotrophin-releasing hormone (GnRH) pulse generator at the onset of puberty. Genetic mechanisms from single gene mutations to single nucleotide polymorphism associated with delayed puberty are being identified.

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Wyatt, Amanda K., Monika Zavodna, Jean L. Viljoen, Jo-Ann L. Stanton, Neil J. Gemmell, and Christine L. Jasoni. "Changes in Methylation Patterns of Kiss1 and Kiss1r Gene Promoters across Puberty." Genetics & Epigenetics 5 (January 2013): GEG.S12897. http://dx.doi.org/10.4137/geg.s12897.

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The initiation of mammalian puberty is underpinned by an increase in Kisspeptin (Kiss1) signaling via its receptor (Kiss1r/GPR54) on gonadotropin-releasing hormone (GnRH) neurons. Animals and humans with loss-of-function mutations in Kiss1 or Kiss1r fail to go through puberty. The timing of puberty is dependent on environmental factors, and malleability in puberty timing suggests a mechanism that can translate environmental signals into patterns of Kiss1/Kiss1r gene expression. Epigenetics is a powerful mechanism that can control gene expression in an environment-dependent manner. We investiga

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Diana, SRA, dsouza Verginia, Aisha, et al. "A Study to Assess the Knowledge Regarding Puberty Changes among Female Adolescents in Selected High Schools at Honavar U.K. in a View to Provide Self Instructional Module." Journal of Community and Social Health Nursing 2, no. 1 (2019): 7–9. https://doi.org/10.5281/zenodo.3403479.

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Puberty is the time when you physically become an adult. During puberty, body goes through lots of change and emotions might feel stronger and more intense. People usually start going through puberty between ages 8 and 14. The period between childhood and young adulthood is a period of rapid change: physical, emotional, cognitive and social. A descriptive research design was done and the data was collected with the structured questionnaire. A sample of 50 adolescent girls. The aim of the study is to assess the knowledge regarding puberty changes among female adolescents in selected high school

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O’Keeffe, Linda M., Monika Frysz, Joshua A. Bell, Laura D. Howe, and Abigail Fraser. "Puberty timing and adiposity change across childhood and adolescence: disentangling cause and consequence." Human Reproduction 35, no. 12 (2020): 2784–92. http://dx.doi.org/10.1093/humrep/deaa213.

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Abstract STUDY QUESTION Is earlier puberty more likely a result of adiposity gain in childhood than a cause of adiposity gain in adulthood? SUMMARY ANSWER Pre-pubertal fat mass is associated with earlier puberty timing but puberty timing is not associated with post-pubertal fat mass change. WHAT IS KNOWN ALREADY Age at puberty onset has decreased substantially in the last several decades. Whether reducing childhood adiposity prevents earlier puberty and if early puberty prevention itself also has additional independent benefits for prevention of adult adiposity is not well understood. STUDY DE

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Sultana, Nusrat, Faria Afsana, Nazma Akhtar, et al. "Precocious puberty: diagnosis and management." BIRDEM Medical Journal 12, no. 1 (2021): 62–69. http://dx.doi.org/10.3329/birdem.v12i1.57228.

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Precocious puberty is commonly defined as puberty that starts before age 8 years in girls and 9 years in boys. The causes of it may range from a variant of normal development to various pathologic conditions. The etiology of precocious puberty is classified by the underlying pathogenesis into gonadotropin dependent central precocious puberty and peripheral precocious puberty which is independent of gonadotropin but due to different other causes. Variants of precocious puberty include premature thelarche, premature puberche and isolated premature menarche which imply onset of isolated changes w

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Ardayani, Tri, and Neti Sitorus. "Peningkatan Pengetahuan Tentang Puberitas Pada Siswa Kelas 4, 5, 6 SD Negeri Sukawening Kecamatan Ciwidey Kabupaten Bandung." JPKMI (Jurnal Pengabdian Kepada Masyarakat Indonesia) 1, no. 4 (2020): 252–61. http://dx.doi.org/10.36596/jpkmi.v1i4.69.

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Abstrak: Setiap anak pasti mengalami pertumbuhan dan perkembangan secara alami, baik secara fisik, mental dan kematangan organ reproduksi mulai berfungsi dan karakteristik seks sekunder mulai muncul pada remaja tersebut. Usia pubertas pada anak remaja sekitar usia 10 tahun sampai 20 tahun. Pada anak perempuan masa ini ditandai dengan menstruasi (menarche), pertumbuhan payudara, tumbuhnya rambut di daerah kemaluan, sedangkan pada anak laki-laki pada masa pubertas ditandai dengan perubahan suara yang disertai dengan tonjolan kerongkongan (Adam’s apple), perubahan panjang penis, dan tumbuhnya ram

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Calcaterra, Valeria, Elvira Verduci, Vittoria Carlotta Magenes, et al. "The Role of Pediatric Nutrition as a Modifiable Risk Factor for Precocious Puberty." Life 11, no. 12 (2021): 1353. http://dx.doi.org/10.3390/life11121353.

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Puberty is a critical phase of growth and development characterized by a complex process regulated by the neuroendocrine system. Precocious puberty (PP) is defined as the appearance of physical and hormonal signs of pubertal development at an earlier age than is considered normal. The timing of puberty has important public health, clinical, and social implications. In fact, it is crucial in psychological and physical development and can impact future health. Nutritional status is considered as one of the most important factors modulating pubertal development. This narrative review presents an

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Abdulhameed A. Al-Tuhafi, Amenah, and Sajeda Saeed Al-Chalbi. "Changes in bone mineral density during puberty." Tikrit Journal of Pharmaceutical Sciences 8, no. 1 (2023): 68–79. http://dx.doi.org/10.25130/tjphs.2012.8.1.9.68.79.

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Puberty is the fundamental period for bone mass acquisition. In this period mineralization is found to increase with levels of high bone formation.. The objective of this cross-sectional study was to determine the changes in bone mineral density (BMD) and growth parameters for healthy pubertal males and females at different pubertal stages in Mosul city/Iraq. In addition, we aimed to detect the relationship between BMD, age, pubertal stage and growth parameters, and to reveal the most important determinant of BMD in the pubertal period. BMD of the lumbar spine was performed by dual-energy X-ra

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Chinthamreddy Aruna and Achutha Giridhar. "A Precocious Puberty." International Journal of Pharmaceuticals and Health Care Research 13, no. 1 (2025): 27–36. https://doi.org/10.61096/ijphr.v13.iss1.2025.27-36.

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In this review explain Precocious puberty (PP) meanз the appearance of зecondary sexual characters before the age of eight yearз in girlз and nine yearз in boyз. Puberty iз indicated in girls by the enlargement of the breaзtз (thelarche) in girlз and in boyз by the enlargement of the teзteз in either volume or length (teзticular volume = 4 mL, teзticular length = 25 mm, or both). Two types of PP are recognized - namely central PP (CPP) and peripheral PP (PPP). Thiз paper aimз to deзcribe the clinical ﬁndingз and laboratory workup of PP and to illuзtrate the new trendз in the management of prec

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Albertsson-Wikland, Kerstin, Sten Rosberg, Birgitta Lannering, Leo Dunkel, Gunnar Selstam, and Ensio Norjavaara. "Twenty-Four-Hour Profiles of Luteinizing Hormone, Follicle-Stimulating Hormone, Testosterone, and Estradiol Levels: A Semilongitudinal Study throughout Puberty in Healthy Boys*." Journal of Clinical Endocrinology & Metabolism 82, no. 2 (1997): 541–49. http://dx.doi.org/10.1210/jcem.82.2.3778.

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Abstract To follow and correlate gonadotropin and sex steroid changes throughout puberty, 24-h profiles of LH, FSH, testosterone, and estradiol were taken on several occasions for between 2–9.5 yr in 12 healthy boys, aged 8.7–18.2 yr. Serum concentrations of LH and FSH were measured every 20 min, whereas testosterone and estradiol were measured every 2–4 h during the 24-h period. The prepubertal boys (Tanner stage 1) were subdivided into two groups: Pre 1, with a testicular volume of 1–2 mL, and Pre 2, with a testicular volume of 3 mL. Pubertal stages were classified, according to testicular v

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Tria Jaya, Susanti, and Nurin Fauziyah. "PENDIDIKAN KESEHATAN TENTANG PERSONAL HYGIENE DI MASA PUBERTAS PADA SISWA KELAS 5 DAN KELAS 6 DI SDN WATES KECAMATAN WATES." Jurnal Abdimas Pamenang 2, no. 1 (2024): 80–85. http://dx.doi.org/10.53599/jap.v2i1.200.

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Tahapan perkembangan manusia salah satunya adalah pubertas. Pada masa pubertas terjadi perubahan diri dari masa kanak – kanak menuju dewasa, sehingga terjadi perubahan fisik, sikap, perilaku dan pematangan organ reproduksi. Pengabdian masyarakat dilakukan dengan meningkatkan pengetahuan siswi Sekolah dasar (SD) yang memasuki usia pra remaja tentang bagaimana menjaga kebersihan diri / personal hygiene di masa pubertas pada anak SDN Wates. SDN Wates merupakan salah satu sekolah dasar di Kabupaten Kediri. Setiap tingkat dibagi dalam 3 kelas pembelajaran. Dalam kegiatan pengabdian masyarakat ini d

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SIMON, A. E., J. WARDLE, M. J. JARVIS, N. STEGGLES, and M. CARTWRIGHT. "Examining the relationship between pubertal stage, adolescent health behaviours and stress." Psychological Medicine 33, no. 8 (2003): 1369–79. http://dx.doi.org/10.1017/s0033291703008390.

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Background. This paper examines the associations between puberty and three important health behaviours (smoking, food intake and exercise) and explores whether these associations are mediated by puberty's relationship to stress and psychological difficulties.Method. Data were taken from the first year of the ongoing, 5-year, Health and Behaviours in Teenagers Study (HABITS). This is a school-based study set in 36 schools in London. In the first year of the study, 4320 students (2578 boys, 1742 girls) in their first year of secondary education took part.Results. Among girls, being more pubertal

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Marshall-Andon, Tess. "Disorders of puberty." InnovAiT: Education and inspiration for general practice 10, no. 1 (2016): 20–28. http://dx.doi.org/10.1177/1755738016676286.

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Disorders of puberty are relatively common problems that affect young people and include precocious puberty and delayed puberty. The disorders of puberty may go unrecognised, as the signs and symptoms may be subtle, and the patient may be embarrassed to bring concerns to the attention of the GP. They are not only a source of significant emotional distress for young people, but also can also lead to long-term adverse consequences, such as failure to achieve target height. Disorders of puberty may also be a sign of a serious underlying condition, which if promptly diagnosed may be treatable. The

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Li, Qingnan, Xiangchun Pan, Nian Li, Wentao Gong, Yaosheng Chen, and Xiaolong Yuan. "Identification of Circular RNAs in Hypothalamus of Gilts during the Onset of Puberty." Genes 12, no. 1 (2021): 84. http://dx.doi.org/10.3390/genes12010084.

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The disorders of puberty have shown negative outcomes on health of mammals, and the hypothalamus is thought to be the main regulator of puberty by releasing GnRH. Many studies show that the circular RNAs (circRNAs) might be implicated in the timing of puberty in mammals. However, the circRNAs in the hypothalamus of gilts have not been explored. To profile the changes and biological functions of circRNAs in the hypothalamus during the onset of puberty, RNA-seq was utilized to establish pre-, in-, and post-pubertal hypothalamic circRNAs profiles. In this study, the functions of hypothalamic circ

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Al Alwan, Ibrahim, Haifa Alfaraidi, Fahad Al Juraibah, et al. "Timing of Puberty and Late Pubertal Height in Saudi Schoolboys: Riyadh Puberty Study II." International Journal of Endocrinology 2022 (October 20, 2022): 1–8. http://dx.doi.org/10.1155/2022/4343596.

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Objective. Puberty has a significant contribution to the final height. Therefore, it is crucial to understand the normal variations in the onset and tempo of puberty in a specific population. In this study, we aimed to provide normative data on the timing of puberty and late pubertal height (LPH) in Saudi schoolboys in Riyadh. Methods. This is a cross-sectional field study (2011–2013) including Saudi schoolboys (grades 1–12; aged 6 to 19 years). Schools were chosen to represent the population from urban and rural areas in the Riyadh region. Pubertal maturity staging for gonads was assessed by

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Howard, Sasha R. "Genetic regulation in pubertal delay." Journal of Molecular Endocrinology 63, no. 3 (2019): R37—R49. http://dx.doi.org/10.1530/jme-19-0130.

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Delayed puberty represents the clinical presentation of a final common pathway for many different pathological mechanisms. In the majority of patients presenting with significantly delayed puberty, there is a clear family history of delayed or disturbed puberty, and pubertal timing is known to be a trait with strong heritability. Thus, genetic factors clearly play a key role in determining the timing of puberty, and mutations in certain genes are recognised as responsible for delayed or absent puberty in a minority of patients. Through the identification of causal genetic defects such as these

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SA, Kobra. "Correlation of Preinjection Values of Gonadotropins and Estradiol Level with Clinical and Radiologic Evidence of Sufficient Pubertal Suppression in Girls with Central Precocious Puberty." Open Access Journal of Endocrinology 8, no. 1 (2024): 1–6. http://dx.doi.org/10.23880/oaje-16000190.

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Background: In monitoring of precocious puberty treatment, less attention has been paid to the clinical signs and radiological evidence of puberty control. We evaluated the correlation of preinjection values of gonadotropins and estradiol level with clinical criteria of sufficient pubertal suppression in girls with central precocious puberty. Materials and Methods: 34 patients with CPP were included. After 4-19 dose of depot Triptorelin, blood levels of Estradiol, LH and FSH was measured before next dose of drug. The growth velocity and the bone age advancement were calculated. Correlation of

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Darendeliler, F., P. C. Hindmarsh, M. A. Preece, L. Cox, and C. G. D. Brook. "Growth hormone increases rate of pubertal maturation." Acta Endocrinologica 122, no. 3 (1990): 414–16. http://dx.doi.org/10.1530/acta.0.1220414.

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Abstract We have performed a retrospective analysis of the pubertal parameters of 134 children with isolated GH insufficiency on GH treatment and compared them to the standards of Tanner and to a recent longitudinal study of growth and development in the United Kingdom. The age at onset of puberty (13.0 years in boys, 12.1 years in girls) was found to be significantly delayed (Mann-Whitney p<0.001), but duration of puberty (1.5 years in both sexes) was shortened (Kolgomarov-Smirnov p<0.01). Skeletal maturity at the onset of puberty was not advanced excluding this as a contributory factor

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McMurray, Robert G., and Peter A. Hosick. "The Interaction of Obesity and Puberty on Substrate Utilization During Exercise: A Gender Comparison." Pediatric Exercise Science 23, no. 3 (2011): 411–31. http://dx.doi.org/10.1123/pes.23.3.411.

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The study evaluated the interactions of puberty and obesity on substrate oxidation of overweight girls (n = 38) and boys (N = 35; BMI > 85th percentile) matched for gender, age, and puberty (pre/pubertal) with normal weight girls and boys. Metabolic rates (VO2) were obtained during rest and at 4, 5.6 and 8 k/h. Carbohydrate oxidation rates (mg/kgFFM/min) adjusted for % predicted VO2max, were higher for prepubertal OW children than pubertal children (p < .03). Fat oxidation rates were higher for NW prepubertal boys compared with other boys. Results indicate that OW children, regardless of

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Souza, Carolina Martins de, Tamara Yamamoto, and Cristiane Kochi. "Evaluation of statural growth and puberty of children and adolescents with overweight and obesity." Revista de Medicina 100, esp (2021): 7. http://dx.doi.org/10.11606/issn.1679-9836.v100iespp7-7.

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Introduction: Childhood obesity is one of the main public health problems in Brazil and worldwide and is a risk factor for many other metabolic diseases. Furthermore, studies show that being overweight influences growth and puberty. Objectives: In females, being overweight is associated with the anticipation of puberty. However, in males, few studies have been done and they are controversial. Therefore, this study aimed to evaluate growth and puberty in overweight boys and girls. Methods: In this retrospective study, we analyzed the medical records of patients aged 5 to 19 years, overweight or

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