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Journal articles on the topic 'Pulmonary Artery Denervation'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Chen, Lingdan, Neng Wang, Bin Peng, et al. "Pulmonary Artery Denervation." JACC: Cardiovascular Interventions 12, no. 7 (2019): 691–92. http://dx.doi.org/10.1016/j.jcin.2019.01.220.

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2

Leopold, Jane A. "Pulmonary Artery Denervation." JACC: Cardiovascular Interventions 15, no. 23 (2022): 2424–26. http://dx.doi.org/10.1016/j.jcin.2022.10.004.

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3

Hoeper, Marius M. "Pulmonary Artery Denervation." Journal of the American College of Cardiology 76, no. 8 (2020): 927–29. http://dx.doi.org/10.1016/j.jacc.2020.06.067.

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4

Dimopoulos, Konstantinos, Sabine Ernst, Colm McCabe, and Aleksander Kempny. "Pulmonary Artery Denervation." JACC: Cardiovascular Interventions 12, no. 3 (2019): 285–88. http://dx.doi.org/10.1016/j.jcin.2018.10.045.

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5

Rubin, Lewis J. "Pulmonary Artery Denervation for Pulmonary Artery Hypertension." JACC: Cardiovascular Interventions 8, no. 15 (2015): 2024–25. http://dx.doi.org/10.1016/j.jcin.2015.10.022.

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6

Ogo, Takeshi. "Transthoracic Pulmonary Artery Denervation." Arteriosclerosis, Thrombosis, and Vascular Biology 39, no. 6 (2019): 979–81. http://dx.doi.org/10.1161/atvbaha.119.312591.

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7

Fernández-Ruiz, Irene. "Pulmonary artery denervation shows promise." Nature Reviews Cardiology 17, no. 11 (2020): 678. http://dx.doi.org/10.1038/s41569-020-00442-y.

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8

Huang, Yuan, Yi-Wei Liu, Hai-Zhou Pan, et al. "Transthoracic Pulmonary Artery Denervation for Pulmonary Arterial Hypertension." Arteriosclerosis, Thrombosis, and Vascular Biology 39, no. 4 (2019): 704–18. http://dx.doi.org/10.1161/atvbaha.118.311992.

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Objective— Pulmonary arterial hypertension is characterized by progressive pulmonary vascular remodeling and persistently elevated mean pulmonary artery pressures and pulmonary vascular resistance. We aimed to investigate whether transthoracic pulmonary artery denervation (TPADN) attenuated pulmonary artery (PA) remodeling, improved right ventricular (RV) function, and affected underlying mechanisms. We also explored the distributions of sympathetic nerves (SNs) around human PAs for clinical translation. Approach and Results— We identified numerous SNs in adipose and connective tissues around

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9

Chen, Shao-Liang, Feng-Fu Zhang, Jing Xu, et al. "Pulmonary Artery Denervation to Treat Pulmonary Arterial Hypertension." Journal of the American College of Cardiology 62, no. 12 (2013): 1092–100. http://dx.doi.org/10.1016/j.jacc.2013.05.075.

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10

Mamchur, S. E., E. V. Tokmakov, O. A. Nagirniak, et al. "Pulmonary artery ganglionic plexi radiofrequency ablation using non-fluoroscopic navigation for the treatment of pulmonary hypertension: a pilot study." Complex Issues of Cardiovascular Diseases 7, no. 4S (2019): 36–46. http://dx.doi.org/10.17802/2306-1278-2018-7-4s-36-46.

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Aim. To evaluate the safety of the pulmonary artery radiofrequency catheter denervation in different pulmonary hypertension (PH) clinical forms.Methods. 6 patients with different clinical forms of PH were included in the study with the further randomization into two groups. Group I patient (n = 3) underwent pulmonary denervation and group II patients (n = 3) underwent a placebo procedure. The examination of patients included routine clinical tests, the measurements of N-terminal precursor of the brain natriuretic peptide (NT-proBNP) levels, coagulation blood tests, ECG recordings, echocardiogr

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11

Feshchenko, D. A., B. A. Rudenko, A. S. Shanoyan, et al. "Pulmonary artery denervation in patients with pulmonary hypertension: present state and clinical experience." Russian Journal of Cardiology, no. 12 (December 28, 2019): 162–68. http://dx.doi.org/10.15829/1560-4071-2019-12-.

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Despite treatment advances, the prognosis of patients with both primary and secondary pulmonary hypertension (PH) remains unfavorable. The increased activity of the sympathetic nervous system is one of the universal mechanisms involved in the PH pathogenesis. Pulmonary artery denervation is a novel minimally invasive pathogenetic method of PH treatment. The denervation procedure is mainly implemented by using radiofrequency ablation of the pulmonary trunk, where most sympathetic nerve fibers are located. In this article we present an overview and analysis of the present state, results of vario

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Feshchenko, D. A., B. A. Rudenko, A. S. Shanoyan, et al. "Pulmonary artery denervation in patients with pulmonary hypertension: present state and clinical experience." Russian Journal of Cardiology, no. 12 (December 28, 2019): 162–68. http://dx.doi.org/10.15829/1560-4071-2019-12-162-168.

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Despite treatment advances, the prognosis of patients with both primary and secondary pulmonary hypertension (PH) remains unfavorable. The increased activity of the sympathetic nervous system is one of the universal mechanisms involved in the PH pathogenesis. Pulmonary artery denervation is a novel minimally invasive pathogenetic method of PH treatment. The denervation procedure is mainly implemented by using radiofrequency ablation of the pulmonary trunk, where most sympathetic nerve fibers are located. In this article we present an overview and analysis of the present state, results of vario

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13

Le, Trixie, Christian Makar, Philip Morway, Nir Hoftman, and Soban Umar. "Pulmonary artery denervation: a novel treatment modality for pulmonary hypertension." Journal of Thoracic Disease 11, no. 4 (2019): 1094–96. http://dx.doi.org/10.21037/jtd.2019.02.93.

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14

Evlakhov, V. I., I. Z. Poiasov, and V. I. Ovsiannikov. "Pulmonary artery denervation in pulmonary hypertension: physiological and clinical aspects." Angiology and vascular surgery 27, no. 3 (2021): 16. http://dx.doi.org/10.33529/angio2021309.

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15

Azovtsev, Rostislav A., and Vadim I. Evlakhov. "Renal artery denervation: unsolved questions about mechanisms of changes of systemic hemodynamics." Medical academic journal 22, no. 3 (2022): 5–14. http://dx.doi.org/10.17816/maj106891.

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In the review we discussed the clinical and physiological aspects of the use of renal artery denervation as an interventional method of treatment of refractory essential arterial hypertension. The application of radiofrequency denervation may be considered as an additional treatment to drug therapy in patients with arterial hypertension. At the same time, the main emphasis in the performed experimental and clinical studies was made on the assessment of changes in blood pressure, cardiac output and the calculated index of total peripheral resistance. However, there is no satisfactory data in th

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Rothman, Alex, Michael Jonas, David Castel, et al. "Pulmonary artery denervation using catheter-based ultrasonic energy." EuroIntervention 15, no. 8 (2019): 722–30. http://dx.doi.org/10.4244/eij-d-18-01082.

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17

Mahfoud, Felix, and Felix Götzinger. "Pulmonary artery denervation – the suspense continues?" EuroIntervention 19, no. 8 (2023): 623–24. http://dx.doi.org/10.4244/eij-e-23-00033.

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18

Fukumitsu, Masafumi, and Keita Saku. "Pulmonary artery denervation: From hope to clinical reality." International Journal of Cardiology 431 (July 2025): 133225. https://doi.org/10.1016/j.ijcard.2025.133225.

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19

Romanov, Alexander, Alexander Cherniavskiy, Nataliya Novikova, et al. "Pulmonary Artery Denervation for Patients With Residual Pulmonary Hypertension After Pulmonary Endarterectomy." Journal of the American College of Cardiology 76, no. 8 (2020): 916–26. http://dx.doi.org/10.1016/j.jacc.2020.06.064.

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20

Smits, A. W., N. H. West, and W. W. Burggren. "Pulmonary fluid balance following pulmocutaneous baroreceptor denervation in the toad." Journal of Applied Physiology 61, no. 1 (1986): 331–37. http://dx.doi.org/10.1152/jappl.1986.61.1.331.

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Pulmonary hemodynamics and net transcapillary fluid flux (NTFF) were measured in conscious toads before and following bilateral denervation of the recurrent laryngeal nerves (rLN), which contain afferents from baroreceptors located in the pulmocutaneous arteries. Denervation caused an acute doubling of the arterial-venous pressure gradient across the lung and a threefold increase in pulmonary blood flow. Calculated pulmonary vascular resistance fell and remained below control values through the period of experimentation. NTFF increased by an order of magnitude (0.74–7.77 ml X kg-1 X min-1), as

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21

Trofimov, N. A., A. P. Medvedev, V. Y. Babokin, et al. "Circular Sympathetic Pulmonary Artery Denervation in Cardiac Surgery Patients With Mitral Valve Defect, Atrial Fibrillation and High Pulmonary Hypertension." Kardiologiia 60, no. 1 (2020): 35–42. http://dx.doi.org/10.18087/cardio.2020.1.n771.

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Objective Investigate the influence of the sympathetic denervation of the pulmonary trunk and the orifices of the pulmonary arteries on the degree of pulmonary hypertension (PH) and outcomes of the surgical treatment of atrial fibrillation (AF) in patients with mitral valve defects, complicated AF, and high PH.Material and methods We analyzed the surgical treatment of 140 patients with mitral valve defect, concomitant AF, and high PH – pulmonary artery systolic pressure (PASP) gradient more than 40 mm Hg. The group of interest included 51 patients (46 patients with severe mitral stenosis and f

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22

Rothman, Alexander M. K., Jean-Luc Vachiery, Luke S. Howard, et al. "Intravascular Ultrasound Pulmonary Artery Denervation to Treat Pulmonary Arterial Hypertension (TROPHY1)." JACC: Cardiovascular Interventions 13, no. 8 (2020): 989–99. http://dx.doi.org/10.1016/j.jcin.2019.12.027.

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23

Zhang, Yao-Jun, Ming-Hui Li, and Shao-Liang Chen. "Pulmonary arterial hypertension: pharmacologic therapies and potential pulmonary artery denervation treatment." EuroIntervention 9, R (2013): R149—R154. http://dx.doi.org/10.4244/eijv9sra25.

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24

Rudenko, B., A. Shanoyan, O. Drapkina, et al. "Simplicity Denervation System for Pulmonary Artery Denervation in Patients with Residual Pulmonary Hypertension after Pulmonary Thromboembolism and Surgical Thrombectomy." Cardiology and Cardiovascular Medicine 01, no. 05 (2017): 200–209. http://dx.doi.org/10.26502/fccm.92920024.

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25

Spradley, C. D. "Pulmonary Artery Denervation to Treat Pulmonary Arterial Hypertension: The Single-Center, Prospective, First-in-Man PADN-1 Study (First-in-Man Pulmonary Artery Denervation for Treatment of Pulmonary Artery Hypertension)." Yearbook of Pulmonary Disease 2014 (2014): 156–57. https://doi.org/10.1016/j.ypdi.2014.02.004.

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26

Vorla, Mounica, Dipsa Shastri, Amit Rout, et al. "C-17 | Efficacy of Pulmonary Artery Denervation Therapy for the Treatment of Pulmonary Artery Hypertension." Journal of the Society for Cardiovascular Angiography & Interventions 2, no. 3 (2023): 100803. http://dx.doi.org/10.1016/j.jscai.2023.100803.

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27

Guo, Fan, and Zhi-Cheng Jing. "Beyond medications: is pulmonary artery denervation the answer for pulmonary arterial hypertension?" AsiaIntervention 8, no. 1 (2022): 14–15. http://dx.doi.org/10.4244/aij-e-22-00001.

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28

Chen, Shao-Liang, Yao-Jun Zhang, Lin Zhou, et al. "Percutaneous pulmonary artery denervation completely abolishes experimental pulmonary arterial hypertension in vivo." EuroIntervention 9, no. 2 (2013): 269–76. http://dx.doi.org/10.4244/eijv9i2a43.

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29

Tannu, Manasi, and Richard A. Krasuski. "The Evolution of Pulmonary Artery Denervation for Treatment of Pulmonary Arterial Hypertension." Interventional Cardiology Clinics 12, no. 3 (2023): 381–91. http://dx.doi.org/10.1016/j.iccl.2023.03.005.

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30

Chhabra, Shibba, J. Cecily Mary Majella, and Anshuman Gupta. "Transcatheter interventions in refractory pulmonary artery hypertension and pulmonary embolism." Indian Journal of Cardiovascular Disease in Women 8 (March 1, 2023): 52–57. http://dx.doi.org/10.25259/ijcdw_13_2023.

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Pulmonary artery hypertension causes remodeling of distal pulmonary arterial vasculature leading to increased resistance of the pulmonary arterial system, right ventricular dysfunction, and sudden cardiac death. The diagnosis of pulmonary arterial hypertension (PAH) diagnosis is made when mean pulmonary artery pressure during catheterization is ≥25 mmHg at rest, pulmonary vascular resistance (PVR) more than 3 wood units, a pulmonary capillary wedge pressure of <15 mmHg. One year survival rate is 86.3% and 5 year survival rate in PAH is 61.2%, and only 7 years of median survival. Although se

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31

Jiang, Xiaomin, Juan Zhang, Ling Zhou, et al. "Sympathetic innervation of canine pulmonary artery and morphometric and functional analysis in dehydromonocrotaline-induced models after pulmonary artery denervation." Interactive CardioVascular and Thoracic Surgery 31, no. 5 (2020): 708–17. http://dx.doi.org/10.1093/icvts/ivaa166.

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Abstract OBJECTIVES We aimed to describe the anatomic distribution of periarterial pulmonary sympathetic nerves and to observe the long-term morphometric and functional changes after pulmonary artery denervation (PADN), a novel therapy for pulmonary arterial hypertension (PAH). METHODS A total of 45 beagles were divided into a sympathetic innervation group (n = 3, 33.3% were females), a PAH group (n = 35, 34.3% were females) and a control group (n = 7, 28.5% were females). The PAH group was randomly divided into no-PADN (n = 7), instant-PADN (n = 7), 1M-PADN (n = 7), 2M-PADN (n = 7) and 3M-PAD

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32

Korobchenko, L. E., N. S. Goncharova, H. I. Condori Leandro, et al. "Pulmonary artery denervation for pulmonary hypertension: a systematic review and meta-analysis of clinical studies." "Arterial’naya Gipertenziya" ("Arterial Hypertension") 27, no. 6 (2022): 628–41. http://dx.doi.org/10.18705/1607-419x-2021-27-6-628-641.

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Objective. To analyze the results of clinical studies on pulmonary artery denervation (PADN) for pulmonary hypertension treatment.Design and methods. Study search was conducted in PubMed/Medline, Cochrane, Elibrary databases. The analysis included studies of surgical and transcatheter PADN. To assess the effectiveness of the PADN procedure, a mean pulmonary artery pressure (mPAP) and a 6-minute walk test distance (6-MWT) were selected. For each study, the mean change in mPAP and 6-MWT were calculated and included in the analysis.Results. A total of 8 studies were analyzed: 4 randomized and 4 o

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33

Karpov, Andrei, Nikita Vachrushev, Leonid Shilenko, et al. "Sympathetic Denervation and Pharmacological Stimulation of Parasympathetic Nervous System Prevent Pulmonary Vascular Bed Remodeling in Rat Model of Chronic Thromboembolic Pulmonary Hypertension." Journal of Cardiovascular Development and Disease 10, no. 2 (2023): 40. http://dx.doi.org/10.3390/jcdd10020040.

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Chronic thromboembolic pulmonary hypertension (CTEPH) develops in 1.5–2.0% of patients experiencing pulmonary embolism (PE) and is characterized by stable pulmonary artery obstruction, heart failure, and poor prognosis. Little is known about involvement of autonomic nervous system (ANS) in the mechanisms of CTEPH. This study was aimed at evaluation of the effect of vagal and sympathetic denervation, as well as stimulation of the parasympathetic nervous system, on the outcomes of CTEPH in rats. CTEPH was induced by multiple intravenous injections of alginate microspheres. Sympathetic and vagal

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34

Rudenko, Boris, Artem Shanoian, Sergey Boytsov, et al. "TCT-825 Simplicity Denervation System for Pulmonary Artery Denervation in Patients with Chronic Thrombembolic Pulmonary Hypertension (first-in-man study)." Journal of the American College of Cardiology 68, no. 18 (2016): B334. http://dx.doi.org/10.1016/j.jacc.2016.09.854.

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35

Zhang, Hang, Wande Yu, Juan Zhang, et al. "Pulmonary artery denervation improves hemodynamics and cardiac function in pulmonary hypertension secondary to heart failure." Pulmonary Circulation 9, no. 2 (2018): 204589401881629. http://dx.doi.org/10.1177/2045894018816297.

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This study aimed to determine the benefits and correlated mechanisms of pulmonary artery denervation (PADN) for heart failure (HF) pulmonary hypertension (PH). PH secondary to HF is associated with poor clinical outcomes because there is no proper therapy for it. PADN showed improved outcomes for patients with HF-PH. However, the underlying mechanisms remain unknown. Supracoronary aortic banding (SAB) was used to create HF-PH models. Sprague-Dawley rats were randomly assigned to control, SAB, sham, SAB with PADN, and SAB without PADN groups. Surgical (longitudinally damaging vessel nerves) and

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36

Rudenko, B. A., D. A. Feshchenko, A. S. Shanoian, et al. "ENDOVASCULAR TREATMENT OF THE RESIDUAL THROMBOEMBOLIC PULMONARY HYPERTENSION AFTER PULMONARY THROMBENDARTERECTOMY WITH THE DENERVATION SYSTEM SYMPLICITY." Cardiovascular Therapy and Prevention 17, no. 2 (2018): 43–48. http://dx.doi.org/10.15829/1728-8800-2018-2-43-48.

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Aim. To assess the safety and efficacy of radiofrequency denervation of pulmonary artery (PA) with the Simplicity system in patients with residual pulmonary hypertension (PH) after the thromberarterectomy surgery.Material and methods. To the study, 12 patients included, with the signs of residual PH (by echocardiography data, mean PH pressure ≥25 mmHg), who had undergone surgery (thrombendarcterectomy) for chronic thromboembolic PH. Mean time interval between the diagnosis of PH and pulmonary denervation was 8,5 years. After catheterization of the right chambers of the heart and tensiometry in

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37

Trofimov, N. A., A. P. Medvedev, V. E. Babokin, et al. "Dynamics of echocardiography parameters after circular PADN procedure in patients with mitral valve defects, atrial fibrillation, and high pulmonary hypertension." Siberian Medical Journal 34, no. 3 (2019): 129–43. http://dx.doi.org/10.29001/2073-8552-2019-34-3-129-143.

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Aim. To analyze the dynamics of echocardiographic parameters after surgical treatment of severe pulmonary hypertension in patients with mitral valve disease and atrial fibrillation.Material and Methods. Data of surgical treatment in 202 patients with mitral valve disease complicated by severe pulmonary hypertension with blood pressure more than 40 mm Hg and atrial fibrillation were analyzed. Surgical intervention in these patients consisted in surgical correction of mitral dysfunction with artificial prosthetic valve or valve-preserving intervention (group 1, n = 62). In patients of group 2 (n

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38

Qingyan, Zhao, Jiang Xuejun, Tang Yanhong, et al. "Beneficial Effects of Renal Denervation on Pulmonary Vascular Remodeling in Experimental Pulmonary Artery Hypertension." Revista Española de Cardiología (English Edition) 68, no. 7 (2015): 562–70. http://dx.doi.org/10.1016/j.rec.2014.11.022.

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39

Abouzid, Mohamed Riad, Samar Eldahtoury, Sunita Devi, and Shorouk Elshafei. "PULMONARY ARTERY DENERVATION IN PULMONARY HYPERTENSION: A COMPREHENSIVE METAANALYSIS OF CLINICAL AND EXPERIMENTAL STUDIES." Journal of the American College of Cardiology 83, no. 13 (2024): 2111. http://dx.doi.org/10.1016/s0735-1097(24)04101-9.

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40

Chernyavskiy, Alexander M., Alexander G. Edemskiy, Oksana Y. Vasiltseva, et al. "Chronic thromboembolic pulmonary hypertension: epidemiology, diagnosis, treatment — current state of the problem." Annals of the Russian academy of medical sciences 78, no. 4 (2023): 297–304. http://dx.doi.org/10.15690/vramn13995.

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Chronic thromboembolic pulmonary hypertension is group IV of pulmonary hypertension, which develops with occlusive-stenotic lesions of the pulmonary artery after a pulmonary embolism. There are no clear data on the epidemiology of this disease. At the same time, it is obvious that it is much more widespread than is commonly believed. This is due to the nonspecific clinical picture and the lack of awareness of clinicians about this disease. On the one hand, the pathogenesis of CTEPH is well studied and in many respects similar to pulmonary arterial hypertension, on the other hand, it is not cle

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García-Lunar, Inés, Daniel Pereda, Borja Ibanez, and Ana García-Álvarez. "Neurohormonal Modulation as a Therapeutic Target in Pulmonary Hypertension." Cells 9, no. 11 (2020): 2521. http://dx.doi.org/10.3390/cells9112521.

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The autonomic nervous system (ANS) and renin-angiotensin-aldosterone system (RAAS) are involved in many cardiovascular disorders, including pulmonary hypertension (PH). The current review focuses on the role of the ANS and RAAS activation in PH and updated evidence of potential therapies targeting both systems in this condition, particularly in Groups 1 and 2. State of the art knowledge in preclinical and clinical use of pharmacologic drugs (beta-blockers, beta-three adrenoceptor agonists, or renin-angiotensin-aldosterone signaling drugs) and invasive procedures, such as pulmonary artery dener

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42

Zhou, Ling, Juan Zhang, Xiao-Min Jiang, et al. "Pulmonary Artery Denervation Attenuates Pulmonary Arterial Remodeling in Dogs With Pulmonary Arterial Hypertension Induced by Dehydrogenized Monocrotaline." JACC: Cardiovascular Interventions 8, no. 15 (2015): 2013–23. http://dx.doi.org/10.1016/j.jcin.2015.09.015.

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43

何, 加劲. "Efficacy of Commonly Targeted Drugs versus Pulmonary Artery Denervation for Pulmonary Hypertension: A Systematic Review." Advances in Clinical Medicine 12, no. 07 (2022): 6943–52. http://dx.doi.org/10.12677/acm.2022.1271001.

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44

Chen, Shao-Liang, Hang Zhang, Du-Jiang Xie, et al. "Pericardial effusion is correlated with clinical outcome after pulmonary artery denervation for pulmonary arterial hypertension." Oncotarget 8, no. 33 (2016): 54106–14. http://dx.doi.org/10.18632/oncotarget.14031.

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45

Condori Leandro, Heber Ivan, Elena G. Koshevaya, Lubov B. Mitrofanova, et al. "An Ovine Model for Percutaneous Pulmonary Artery Laser Denervation: Perivascular Innervation and Ablation Lesion Characteristics." International Journal of Molecular Sciences 22, no. 16 (2021): 8788. http://dx.doi.org/10.3390/ijms22168788.

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Background: Pulmonary artery denervation (PADN) is an evolving interventional procedure capable to reduce pulmonary artery (PA) pressure. We aimed to compare PA nerve distribution in different specimens and assess the feasibility of an ovine model for a denervation procedure and evaluate the acute changes induced by laser energy. Methods: The experiment was divided into two phases: (1) the analysis of PA nerve distribution in sheep, pigs, and humans using histological and immunochemical methods; (2) fiberoptic PADN in sheep and postmortem laser lesion characteristics. Results: PA nerve density

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46

Yokoyama, Yasutaka, Satoshi Matsushita, Takafumi Iesaki, et al. "Denervation of gastroepiploic artery graft can reduce vasospasm." Journal of Thoracic and Cardiovascular Surgery 147, no. 3 (2014): 951–55. http://dx.doi.org/10.1016/j.jtcvs.2013.02.022.

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47

Shirai, M., K. Matsukawa, N. Nishiura, A. T. Kawaguchi, and I. Ninomiya. "Changes in efferent pulmonary sympathetic nerve activity during systemic hypoxia in anesthetized cats." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 269, no. 6 (1995): R1404—R1409. http://dx.doi.org/10.1152/ajpregu.1995.269.6.r1404.

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Changes in efferent sympathetic nerve activity to the pulmonary vessels during systemic hypoxia have yet to be elucidated. The purpose of this study was to determine the pulmonary sympathetic nerve activity (PSNA) changes in response to acute systemic hypoxia before and after sinoaortic denervation plus vagotomy in anesthetized cats. The denervation was performed to estimate the central nervous system-mediated peripheral chemoreceptor- and baroreceptor-independent PSNA change. PSNA was recorded from the central end of the cut nerve bundle, which was isolated from the lobar artery supplying the

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48

Vakhrushev, Aleksandr D., Heber Ivan Condori Leandro, Natalia S. Goncharova, et al. "Extended Renal Artery Denervation Is Associated with Artery Wall Lesions and Acute Systemic and Pulmonary Hemodynamic Changes: A Sham-Controlled Experimental Study." Cardiovascular Therapeutics 2020 (October 28, 2020): 1–8. http://dx.doi.org/10.1155/2020/8859663.

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Objectives. We sought to assess acute changes in systemic and pulmonary hemodynamics and microscopic artery lesions following extended renal artery denervation (RDN). Background. RDN has been proposed to reduce sympathetic nervous system hyperactivation. Although the effects of RDN on systemic circulation and overall sympathetic activity have been studied, data on the impact of RDN on pulmonary hemodynamics is lacking. Methods. The study comprised 13 normotensive Landrace pigs. After randomization, 7 animals were allocated to the group of bilateral RDN and 6 animals to the group of a sham proc

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49

Trofimov, N. A., A. V. Nikolskiy, A. L. Rodionov, D. V. Egorov, and T. V. Surkova. "Assessment of morphological criteria for the efficiency of radiofrequency circumferential denervation of the pulmonary artery in the experiment (animals, pigs)." Acta Biomedica Scientifica 7, no. 5-2 (2022): 131–42. http://dx.doi.org/10.29413/abs.2022-7.5-2.14.

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The aim of the study. To assess the influence of radiofrequency circumferential exposure modes on the morphological parameters of the pulmonary artery tissues in animal experiment (pigs).Material and methods. In the experiments, we used outbred pigs divided into 3 groups (4 animals in each). The first experimental group included 188 histological samples of the pulmonary arteries (PA) after radiofrequency circumferential exposure on the PA using an ablator clamp. Two lines of exposure on the PA and two lines of exposure on each PA mouth were performed. Ablation was performed until the target le

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Zheleznev, S. I., D. P. Demidov, A. V. Afanasiev, et al. "RADIOFREQUENCY DENERVATION OF PULMONARY ARTERY IN SURGERY OF DYSPLASTIC MITRAL VALVE DEFECTS WITH SEVERE PULMONARY HYPERTENSION." Russian Journal of Cardiology, no. 11 (January 1, 2016): 70–72. http://dx.doi.org/10.15829/1560-4071-2016-11-70-72.

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