Academic literature on the topic 'Pulsatile drug delivery system'

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Journal articles on the topic "Pulsatile drug delivery system"

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Sharma, Abhimanyu Rai, Binu Raina, Prabhjot Singh Bajwa, Anurag Bhargava, Toshiba Toshiba, and Vrinda Goel. "Pulsatile Drug Delivery System-A Review." Asian Pacific Journal of Health Sciences 5, no. 3 (2018): 260–70. http://dx.doi.org/10.21276/apjhs.2018.5.3.38.

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Kundan Rajendra Mahajan, Ashish Prakash Gorle, and Vijay Sanjay Khalane. "Overview on pulsatile drug delivery system." International Journal of Science and Research Archive 5, no. 2 (2022): 110–18. http://dx.doi.org/10.30574/ijsra.2022.5.2.0067.

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Traditionally, drugs are released in an immediate or extended fashion. However, in recent years, pulsatile drug release systems are gaining growing interest. Pulsatile drug delivery systems are developed to deliver drug according to circadian behavior of diseases. The product follow a sigmoidal drug release profile characterized by a time period of no release (lag time) followed by a rapid and complete drug release. Pulsatile systems are gaining a lot of interest as they deliver the drug at the right site of action at the right time and in the right amount, thus providing spatial and temporal
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Belgamwar, VeenaS, MadhuriV Gaikwad, GaneshB Patil, and Sanjay Surana. "Pulsatile drug delivery system." Asian Journal of Pharmaceutics 2, no. 3 (2008): 141. http://dx.doi.org/10.4103/0973-8398.43297.

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SHARMA, PRASHANT. "Pulsatile Drug Delivery System – A Novel Approach for Time and Spatial Controlled Drug Delivery." Journal of Pharmaceutical Technology, Research and Management 4, no. 1 (2016): 13–29. http://dx.doi.org/10.15415/jptrm.2016.41002.

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Kapila, Arpita* Rambabu Sharma Agarwal Shweta. "PULSATILE DRUG DELIVERY SYSTEM: A MECHANISTIC UPDATE." Indo American Journal of Pharmaceutical Sciences 04, no. 11 (2017): 3928–34. https://doi.org/10.5281/zenodo.1042593.

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Pulsatile drug delivery systems are the systems which deliver the drug according to the circadian rhythm of the body. The product follows a sigmoidal drug release profile characterized by a time period of no release (lag time) followed by a rapid and complete drug release. Thus, these systems deliver the drug at the right site of action at the right time and in the right amount, thus providing spatial and temporal delivery and increasing patient compliance. Various capsular, osmotic, single and multiple unit systems that are modulated by soluble or erodible polymer coatings, rupturable membran
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Garg, Tarun. "PULSATILE DRUG DELIVERY SYSTEMS: PULSINCAP SYSTEM." IOSR Journal of Pharmacy (IOSRPHR) 2, no. 2 (2012): 338–39. http://dx.doi.org/10.9790/3013-0220338339.

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Shelke Amruta P, Wagh Priti A, Nikam Sakshi M, and Bhosale Jaydeep J. "Pulsatile drug delivery system: A review." World Journal of Biology Pharmacy and Health Sciences 21, no. 2 (2025): 457–66. https://doi.org/10.30574/wjbphs.2025.21.2.0187.

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Pulsatile Drug Delivery Systems (PDDS) are increasingly recognized for their ability to deliver drugs at specific times, tailored to the pathophysiological needs of a disease. This approach enhances therapeutic efficacy and patient compliance. The core concept of PDDS involves a defined lag-time before a rapid drug release, which can be particularly beneficial for treatments requiring synchronization with the body’s natural circadian rhythms. By aligning peak plasma concentrations with these biological cycles, PDDS can improve both the safety and effectiveness of drugs over a 24-hour period. T
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Albadri, Ahmed A., Mustafa R. Abdulbaqi, and Yasir Q. Almajidi. "Recent Trends in Chronopharmaceutics, Pulsatile Drug Delivery System." Al Mustansiriyah Journal of Pharmaceutical Sciences 19, no. 4 (2019): 41–49. http://dx.doi.org/10.32947/ajps.v19i4.631.

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Pulsatile Drug Delivery Systems (PDDS) are getting considerable interest in delivering a drug at the correct position, at the correct time, and in the correct quantity, thus offering temporal, spatial, and intelligent delivery with improving patient compliance. These systems are
 
 intended to meet body's biological rhythm. Here, the delivery of drugs is assisted by the rhythm of disease. The main reason for the using pulsatile drug release is when the continuous drug release is not required. A PDDS must be designed in such a way that after the lag time a complete and fast release of
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D., K. Singh, Poddar A.S., Nigade S.U., and S. Poddar S. "Pulsatile Drug Delivery System: An Overview." International Journal of Current Pharmaceutical Review and Research 2, no. 2 (2011): 55–80. https://doi.org/10.5281/zenodo.12698485.

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Pulsatile drug delivery systems (PDDS) are gaining importance as they deliver a drug atspecific time as per the pathophysiological need of the disease, resulting in improvedtherapeutic efficacy as well as compliance. Diseases wherein PDDS are promising includeasthma, peptic ulcer, cardiovascular diseases, arthritis, attention deficit syndrome in children,and hypercholesterolemia. These delivery systems can be classified into time controlledwherein the drug release is governed primarily by the delivery system; stimuli induced inwhich release is controlled by a stimuli, like the pH or enzymes pr
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Hussein, Mayssam, and Israa Nathir. "Pulsatile Drug Delivery System Utilizing Innovative Technology." Pakistan Journal of Medical and Health Sciences 16, no. 6 (2022): 601–6. http://dx.doi.org/10.53350/pjmhs22166601.

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Drugs might be released immediately or over time. Pulsatile medication release systems, on the other hand, have been increasing in popularity in recent years. Many medications or therapies could benefit from pulsatile drug release, in which the drug is released rapidly after a predetermined lag time. Pulsatile release systems come in pairs: multi and separate pulse. Rupturable dose forms are a prominent type of single-pulse device. Other methods have a drug-containing centre covered by both a swelling surface and a semi - permeable barrier polymer layer or membrane that is semipermeable but no
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Dissertations / Theses on the topic "Pulsatile drug delivery system"

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Kwok, Connie Sau-Kuen. "Development of self-assembled molecular structures on polymeric surfaces and their applications as ultrasonically responsive barrier coatings for on-demand, pulsatile drug delivery /." Thesis, Connect to this title online; UW restricted, 2001. http://hdl.handle.net/1773/7999.

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Gandhi, Swapnilkumar J. "Barrier-mediated pulsatile release." Diss., University of Iowa, 2015. https://ir.uiowa.edu/etd/1601.

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Solutes are often most efficiently deployed in discrete pulses, for example in the delivery of herbicides or drugs. Manual application of each pulse can be labor-intensive, automated application of each pulse can be capital intensive, and both are often costly and impractical. Barrier-Mediated Pulsatile Release (BMPR) systems offer a materials-based alternative for automated pulsatile drug delivery, without pumps, power supplies, or complex circuitry. While earlier materials-based approaches such as delayed-release microcapsules are limited to two or three pulses due to the independent nature
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Berton, Damiano <1994&gt. "Microfluidic production of drug delivery system." Master's Degree Thesis, Università Ca' Foscari Venezia, 2021. http://hdl.handle.net/10579/19484.

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Leach, Jeffrey Harold. "Magnetic Targeted Drug Delivery." Thesis, Virginia Tech, 2003. http://hdl.handle.net/10919/31261.

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Methods of guiding magnetic particles in a controlled fashion through the arterial system in vivo using external magnetic fields are explored. Included are discussions of applications, magnetic field properties needed to allow guiding based on particle characteristics, hemodynamic forces, the uniformity of field and gradients, variable tissue characteristics, and imaging techniques employed to view these particles while in transport. These factors influence the type of magnetic guidance system that is needed for an effective drug delivery system. This thesis reviews past magnetic drug deliv
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Ho, Duc Hong Linh 1978. "Packaging for a drug delivery microelectromechanical system." Thesis, Massachusetts Institute of Technology, 2005. http://hdl.handle.net/1721.1/30262.

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Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 2005.<br>Includes bibliographical references (p. 52-55).<br>Local drug delivery is a fast expanding field, and has been a center of attention for researchers in medicine in the last decade. Its advantages over systemic drug delivery are clear in cancer therapy, with localized tumors. A silicon microelectromechanical drug delivery device was fabricated for the purpose of delivering chemotherapeutic agents such-as carmustine, a potent brain cancer drug, directly to the site of the tumor. Limitations
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Dyer, Robert J. (Robert Joseph) 1977. "Needle-less injection system for drug delivery." Thesis, Massachusetts Institute of Technology, 2003. http://hdl.handle.net/1721.1/89388.

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Bright, Anne M. "Towards an improved ocular drug delivery system." Thesis, Aston University, 1992. http://publications.aston.ac.uk/9801/.

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The ultimate aim of this project was to design new biomaterials which will improve the efficiency of ocular drug delivery systems. Initially, it was necessary to review the information available on the nature of the tear fluid and its relationship with the eye. An extensive survey of the relevant literature was made. There is a common belief in the literature that the ocular glycoprotein, mucin, plays an important role in tear film stability, and furthermore, that it exists as an adherent layer covering the corneal surface. If this belief is true, the muco-corneal interaction provides the idea
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Birudaraj, Kondamraj. "Transbuccal drug delivery: In vitro characterization of transport pathway of buspirone and bioadhesive drug delivery system." Scholarly Commons, 2001. https://scholarlycommons.pacific.edu/uop_etds/2733.

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The objective of this research was to investigate two important aspects of buccal drug delivery, transport and mucoadhesion. Buspirone was chosen as a model drug for the in vitro buccal transport studies, polyvinyl alcohol and sodium alginate polymer blends were prepared to investigate the mucoadhesive properties through a Lewis acid-base approach and finally, the effect of formulation factors on the force of mucoadhesion, surface energy parameters, release rate and flux was studied. In vitro permeation studies were conducted to investigate the buccal transport pathway of buspirone. Mathematic
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Warrilow, Philip A. D. "Polyamine conjugates as a potential drug delivery system." Thesis, University of Leicester, 1997. http://hdl.handle.net/2381/30012.

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The work in this thesis has covered three main topics; i) cytotoxic polyamine-conjugates ii) radiation protection polyamine-conjugates iii) polyamine conjugates which probe cellular uptake and DNA binding. The synthesis of these conjugates employed selective protection/deprotection steps, taking advantage of the BOC protecting groups regioselectivity of primary over secondary amines when reacting with naturally occurring polyamines. After promising in vitro and in vivo results of the original spermidine-chlorambucil synthesised by Wheelhouse (1990), attempts were made to improve this compound.
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Bosworth, Mark Erwin. "Evaluation of liposomes as a drug delivery system /." Ann Arbor : University Microfilms International, 1987. http://www.gbv.de/dms/bs/toc/016141032.pdf.

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Books on the topic "Pulsatile drug delivery system"

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Jain, Kewal K., ed. Drug Delivery System. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-0363-4.

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Shah, Nirmal, ed. Nanocarriers: Drug Delivery System. Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-33-4497-6.

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Frost & Sullivan., ed. Programmed drug delivery system markets. Frost & Sullivan, 1988.

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P, Johnson, and Lloyd-Jones J. G. 1944-, eds. Drug delivery system: Fundamentals and techniques. VCH, 1988.

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Jain, Kewal K., ed. Drug Delivery to the Central Nervous System. Humana Press, 2010. http://dx.doi.org/10.1007/978-1-60761-529-3.

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F, Smolen Victor, and Ball LuAnn, eds. Bioavailability control by drug delivery system design. Wiley, 1985.

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Parfenyuk, E. V. Silica nanoparticles as drug delivery system for immunomodulator GMDP. ASME, 2012.

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David, Ganderton, Jones T. M. 1942-, Pharmaceutical Society of Great Britain., and King's College (University of London). Chelsea Dept. of Pharmacy., eds. Drug delivery to the respiratory tract. VCH, 1987.

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Gregory, Gregoriadis, McCormack Brenda, Poste George, North Atlantic Treaty Organization. Scientific Affairs Division., and NATO Advanced Study Institute on Targeting of Drugs: Advances in System Constructs (1993 : Ákra Soúnion, Greece), eds. Targeting of drugs 4: Advances in system constructs. Plenum Press, 1994.

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Geest, Ronald van der. PK/PD based drug delivery system design: Iontophoretic apomorphine delivery in patients with Parkinson's disease. University of Leiden], 1998.

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Book chapters on the topic "Pulsatile drug delivery system"

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Kawabuchi, Minako, Atsushi Watanabe, Masayasu Sugihara, Akihiko Kikuchi, Yasuhisa Sakurai, and Teruo Okano. "The Pulsatile Release System of Macromolecular Drugs from Alginate Gel Beads." In Advanced Biomaterials in Biomedical Engineering and Drug Delivery Systems. Springer Japan, 1996. http://dx.doi.org/10.1007/978-4-431-65883-2_106.

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Thitinan, Sumalee, and Jason T. McConville. "Pulsatile Delivery for Controlling Drug Release." In Controlled Release in Oral Drug Delivery. Springer US, 2011. http://dx.doi.org/10.1007/978-1-4614-1004-1_9.

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Makino, Kimiko. "Drug Delivery System." In Electrical Phenomena at Interfaces and Biointerfaces. John Wiley & Sons, Inc., 2012. http://dx.doi.org/10.1002/9781118135440.ch40.

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Godin, Biana, Elka Touitou, Rajaram Krishnan, et al. "Drug Delivery System." In Encyclopedia of Nanotechnology. Springer Netherlands, 2012. http://dx.doi.org/10.1007/978-90-481-9751-4_100192.

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Yang, Qiuhong, and Laird Forrest. "Drug Delivery to the Lymphatic System." In Drug Delivery. John Wiley & Sons, Inc, 2016. http://dx.doi.org/10.1002/9781118833322.ch21.

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On, Ngoc H., Vinith Yathindranath, Zhizhi Sun, and Donald W. Miller. "Pathways for Drug Delivery to the Central Nervous System." In Drug Delivery. John Wiley & Sons, Inc, 2016. http://dx.doi.org/10.1002/9781118833322.ch16.

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Zhang, Yan, and Donald W. Miller. "Pathways for Drug Delivery to the Central Nervous System." In Drug Delivery. John Wiley & Sons, Inc., 2005. http://dx.doi.org/10.1002/0471475734.ch3.

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Choudhary, Princy, and Sangeeta Singh. "Targeted Drug Delivery." In Biotechnology in the Modern Medicinal System. Apple Academic Press, 2021. http://dx.doi.org/10.1201/9781003129783-2.

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Gujarathi, Nayan A., Akshada A. Bakliwal, Bhushan R. Rane, et al. "Pulmonary Drug Delivery System." In Topical and Transdermal Drug Delivery Systems. Apple Academic Press, 2022. http://dx.doi.org/10.1201/9781003284017-9.

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Pillai, Akhilraj, Dhanashree Bhande, and Vinal Pardhi. "Controlled Drug Delivery System." In Studies in Mechanobiology, Tissue Engineering and Biomaterials. Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-6564-9_11.

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Conference papers on the topic "Pulsatile drug delivery system"

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M, Moorthi, Gugan B.M, Mohammed Suhail K.S, et al. "Microfluidic Analysis of Micro Needle for Drug Delivery." In 2024 Control Instrumentation System Conference (CISCON). IEEE, 2024. http://dx.doi.org/10.1109/ciscon62171.2024.10696860.

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Jaiswal, Shalini, Pooja Singh, Shalini Srivastav, Renu Chaudhary, and Atul Kumar. "Noval Technology of Nano-Robot for Promising Drug Delivery System." In 2024 7th International Conference on Contemporary Computing and Informatics (IC3I). IEEE, 2024. https://doi.org/10.1109/ic3i61595.2024.10829002.

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Maloney, John M. "An Implantable Microfabricated Drug Delivery System." In ASME 2003 International Mechanical Engineering Congress and Exposition. ASMEDC, 2003. http://dx.doi.org/10.1115/imece2003-43186.

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We report on the development of a fully implantable drug delivery system capable of delivering hundreds of individual doses. This product is intended for the controlled release of potent therapeutic compounds that might otherwise require frequent injections. Our system has the following capabilities: • Stable, hermetic storage of therapeutic drugs in solid, liquid, or gel form; • Individual storage of discrete doses for multiple-drug regimens; • Wireless communication with an external controller for device monitoring and therapy modification; • Choice of preprogrammed release or release on com
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Divetia, Asheesh, Nolan Yoshimura, Guann-Pynn Li, Baruch D. Kuppermann, and Mark Bachman. "Controlled and Programmable Drug Delivery Using a Self-Powered MEMS Device." In ASME 2007 2nd Frontiers in Biomedical Devices Conference. ASMEDC, 2007. http://dx.doi.org/10.1115/biomed2007-38054.

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Controlled and targeted drug delivery systems have gained a lot of interest as they offer numerous benefits such as precise dosing, reduced side-effects and increased patient compliance. We have designed a microelectromechanical systems (MEMS) drug delivery device that is capable of releasing drugs in a controlled and programmable manner. This self-powered device does not require any external stimulation or control to achieve pulsatile release of drugs. The device consists of multiple reservoirs containing the drug embedded together with a water-swellable polymer. The swelling of the polymer u
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Keyes, Joseph T., Bruce R. Simon, and Jonathan P. Vande Geest. "Transport in Pulsatile Axisymmetric Stented Arterial Models From Location-Dependent Variations in Permeability and Mechanical Properties." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53998.

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Drug-eluting stents (DESs) perform their antiproliferative effects through the use of localized drug delivery. The delivery may be computationally modeled to determine efficacy of the DES-tissue system and utilizes coupled convective and diffusive transport. Since the movement of solutes through the wall is via the coupled effects of convective and diffusive transport, the relative influence of these factors provides insight into the governing forces of localized DES drug delivery [1].
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Kadam, Sagar, Shashikant Dhole, and Soham Chitlange. "“FORMULATION AND EVALUATION OF CHRONOTHERAPEUTIC PULSATLE DRUG DELIVERY SYSTEM”." In 42nd International Academic Conference, Rome. International Institute of Social and Economic Sciences, 2018. http://dx.doi.org/10.20472/iac.2018.042.027.

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Divetia, Asheesh, Baruch D. Kuppermann, Guann-Pyng Li, and Mark Bachman. "Diffusion Controlled, Water-Powered Microactuator for Biomedical and Microfluidic Applications." In ASME 2007 5th International Conference on Nanochannels, Microchannels, and Minichannels. ASMEDC, 2007. http://dx.doi.org/10.1115/icnmm2007-30225.

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Current and advanced microfluidic and implantable biomedical devices present an increasing need for controlled mechanical actuation at the micro-scale, without the use of batteries or external power. Implantable applications such as drug delivery microdevices require long term, battery free operation to perform their operation over the course of many months or years. In this paper, we present a micro-electro-mechanical systems (MEMS) microactuator which is water-powered and does not require any external power or control for its operation. Furthermore, we have demonstrated that by controlling t
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Huang, Song-Bin, Min-Hsien Wu, Zhanfeng Cui, Zheng Cui, and Gwo-Bin Lee. "Microdfluidic Based 3-Dimensional Cell Culture Platform." In ASME 2008 First International Conference on Micro/Nanoscale Heat Transfer. ASMEDC, 2008. http://dx.doi.org/10.1115/mnht2008-52292.

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This study reports a new perfusion-based, micro three-dimensional (3-D) cell culture platform for drug testing using enabling microfluidic technologies. In this work, a perfusion-based, micro 3-D cell culture platform is designed and is fabricated based on SU-8 lithography and polydimethylsiloxane (PDMS) replication processes. One of the key features of the system is that the incorporation of a multiple medium pumping mechanism, consisting of 15 membrane-based pneumatic micropumps with serpentine-shape (S-shape) layout, coupled with a pneumatic tank, into the micro 3-D cell culture platform to
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Bin Wang, Junhui Ni, Y. Litvin, D. W. Pfaff, and Qiao Lin. "A microfluidic device for pulsatile transdermal delivery for neurobiological drugs." In 2010 5th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS 2010). IEEE, 2010. http://dx.doi.org/10.1109/nems.2010.5592603.

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"Drug Delivery System." In 2004 2nd IEEE/EMBS International Summer School on Medical Devices and Biosensors. IEEE, 2004. http://dx.doi.org/10.1109/issmd.2004.1689583.

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Reports on the topic "Pulsatile drug delivery system"

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McPhillips, D. M., M. W. Price, J. W. Gibson, and R. A. Casper. Development of an On-Demand, Generic, Drug-Delivery System. Defense Technical Information Center, 1985. http://dx.doi.org/10.21236/ada158550.

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Pflugfelder Ghanashyam S., Stephen C. Broadly Applicable Nanowafer Drug Delivery System for Treating Eye Injuries. Defense Technical Information Center, 2014. http://dx.doi.org/10.21236/ada613401.

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Dash, Alekha K. Novel in Situ Gel Drug Delivery System for Breast Cancer Treatment. Defense Technical Information Center, 2007. http://dx.doi.org/10.21236/ada474685.

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Silva, João, Matheus Warmeling, and Rogério Pagnoncelli. Platelet-rich fibrin as a drug delivery system: a scoping review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.8.0004.

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Sledge, George W. Nanoparticle: Monoclonal Antibody Conjugates: A Novel Drug Delivery System in Human Breast Cancer. Defense Technical Information Center, 2002. http://dx.doi.org/10.21236/ada420569.

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Sledge, George. Nanoparticle: Monoclonal Antibody Conjugates: A Novel Drug Delivery System in Human Breast Cancer. Defense Technical Information Center, 2000. http://dx.doi.org/10.21236/ada393348.

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Choi, Soojeong, Seoeun Oh, and Ildoo Chung. Synthesis and characterization of L-lysine polyurethane (LPU) nanoparticles for drug delivery system. Peeref, 2023. http://dx.doi.org/10.54985/peeref.2307p9824908.

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Choi, Soojeong, Seoeun Oh, and Ildoo Chung. Synthesis and characterization of L-threonine polyurethane (LTHU) nanoparticles for drug delivery system. Peeref, 2023. http://dx.doi.org/10.54985/peeref.2307p3992803.

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Chakraborty, Payel, and Tamilvanan Shunmugaperumal. Simvastatin repurposing towards endometriosis management: The use of self -nanoemulsifying drug delivery system. Peeref, 2023. http://dx.doi.org/10.54985/peeref.2304p6131285.

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Silva, João, Matheus Warmeling, and Rogerio Pagnoncelli. Platelet-rich fibrin as a drug delivery system: Systematic review of in vitro studies. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.8.0005.

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