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Journal articles on the topic 'Pupilometer'

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1

Guevara Codina, Edgar, and Ingrid Ameyalli Hernández-Barrios. "Low-Cost Portable Pupilometer for Circadian Rhythm Studies." Revista Mexicana de Ingeniería Biomédica 45, no. 3 (2024): 68–79. http://dx.doi.org/10.17488/rmib.45.3.4.

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Given the price tag of commercially available devices, developing a low-cost, portable pupilometer based on the Raspberry Pi platform is significant for advancing clinical and research applications in neurology and circadian rhythm studies. This study aimed to design and characterize a pupilometer capable of assessing pupillary light response (PLR) to different wavelengths and its relationship with circadian cycles. Using a Raspberry Pi, a no-infrared filter (NoIR) camera, and custom software, the device was tested on a healthy 24-year-old female subject over 20 days, measuring responses to 63
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Heick, John, and Lauren Entsler. "Correlation between Pupilometer and the Vestibular/Ocular Motor Screening in Division I Female Collegiate Soccer Athletes." Neurology 95, no. 20 Supplement 1 (2020): S2.3—S3. http://dx.doi.org/10.1212/01.wnl.0000719880.39493.e2.

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ObjectiveThe objective of this study was to explore the correlation between pupilometer and Vestibular Ocular Motor Screening on Division 1 female collegiate soccer players.BackgroundConcussions are one of the most prevalent acquired neurologic conditions occurring in young adults with an estimated 1.6 to 3.8 million head injuries.1,2 Concussions are assessed with a variety of measures such as the Vestibular/Ocular Motor Screen (VOMS). Visual disruptions are frequently observed following concussion with an estimated 65%–90% of patients complaining of visual disruption.4,5 A pupilometer measure
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&NA;, &NA;. "New Pupilometer Never Touches Patient." Journal of Clinical Engineering 29, no. 4 (2004): 191. http://dx.doi.org/10.1097/00004669-200410000-00040.

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Ryu, Hee Kyung, and Sun Young Shin. "Clinical Reliability of IOL Master 700 in Measurement of Pupil Diameter and Corneal Curvature." Journal of the Korean Ophthalmological Society 62, no. 8 (2021): 1022–28. http://dx.doi.org/10.3341/jkos.2021.62.8.1022.

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Purpose: To compare IOL Master 700 with autokeratometer and video pupillometer in measurement of pupil diameter and corneal curvature.Methods: Pupil diameter were measured with IOL Master 700 and video pupilometer, horizontal keratometry and vertical keratometry were measured with IOL Master 700 and autokeratometer in 100 eyes of 50 children. Paired t-test and Pearson's correlation analysis were used to compare the differences among the devices. Agreement between measurement was analyzed using Bland Altman plot and intraclass correlation coefficient.Results: Comparing IOL Master 700 and video
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Husna, H. N., and N. Fitriani. "Evaluation of Pupillary Distance (PD) Measurement using Smartphone-based Pupilometer." Journal of Physics: Conference Series 2243, no. 1 (2022): 012001. http://dx.doi.org/10.1088/1742-6596/2243/1/012001.

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Abstract Measurement of the pupillary distance (PD) is one of the important steps of the spectacles-making process. PD measurement can be done using the PD Ruler, Auto-refractometer, and smartphones’ apps. The study aims to evaluate PD measurement apps (Pupil Distance Meter Pro from Vistech Project, PD Pupil Distance for Eye Glasses and VR Headset from Glassify Me, and The Ultimate PD Rule) and compared them with Auto-refractometer as the gold standard. A total of 39 students (age 19-22) were involved in this study. The result of this study indicated that there was no difference between the me
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Tsalpatouros, A., O. Panou-Diamandi, Ch Papageorgiou, et al. "Eye pupil diameter measurement and assessment via a novel pupilometer system." Technology and Health Care 2, no. 3 (1994): 209–13. http://dx.doi.org/10.3233/thc-1994-2304.

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7

Radzius, Aleksandras, Phyllis Welch, Edward J. Cone, and Jack E. Henningfield. "A portable pupilometer system for measuring pupillary size and light reflex." Behavior Research Methods, Instruments, & Computers 21, no. 6 (1989): 611–18. http://dx.doi.org/10.3758/bf03210585.

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김지호, 이영아, 이희성, and KimJaeHwi. "The Effect of Humor Advertising using Pupilometer System - Focusing on the Incongruity-Resolution Theory -." Korean Journal of Consumer and Advertising Psychology 9, no. 1 (2008): 1–24. http://dx.doi.org/10.21074/kjlcap.2008.9.1.1.

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Shirozu, Kazuhiro, Keitaro Murayama, Yuji Karashima, Hidekazu Setoguchi, Tomofumi Miura, and Sumio Hoka. "The relationship between seizure in electroconvulsive therapy and pupillary response using an automated pupilometer." Journal of Anesthesia 32, no. 6 (2018): 866–71. http://dx.doi.org/10.1007/s00540-018-2566-9.

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10

Tsimbal, M., N. Steinberg, D. Khomich, N. Egorov, and A. Tugolukov. "CHANGES IN BINOCULAR PUPILLOMETRY IN ATHLETES AFTER HIGH EXERCISE STRESS." Human Sport Medicine 19, S1 (2019): 30–35. http://dx.doi.org/10.14529/hsm19s104.

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Aim. The article deals with studying the changes in binocular pupillometry to establish vegetative activity in athletes after high exercise stress. Materials and methods. 25 male athletes aged 19–34 years with no health limitations participated in the study. We estimated a set of the commonly accepted parameters of pupillometry (pupil diameter, pupil reaction initiation time, pupil constriction diameter, pupil constriction velocity) by measuring pupil reaction to a light stimulus with the help of a non-contact pupilometer (KVAZAR, Moscow). The examination was conducted prior to physical stress
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Armas, Samantha, Deborah Jehu, Lori Bolgla, and Forest Dutton. "Examining the inter -rater and inter-trial reliability of the NeuroOptics-3000 pupilometer to measure pupillary light response parameters." Archives of Physical Medicine and Rehabilitation 105, no. 4 (2024): e184. http://dx.doi.org/10.1016/j.apmr.2024.02.636.

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Park, Soo-Hyun, Tae Jung Kim, and Sang-Bae Ko. "Isolated reversible mydriasis was associated with the use of nebulized ipratropium bromide: a case series using quantitative pupilometer in Korea." Acute and Critical Care 39, no. 4 (2024): 593–99. http://dx.doi.org/10.4266/acc.2024.00983.

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Background: Abnormal pupillary reactivity is a neurological emergency requiring prompt evaluation to identify its underlying causes. Although isolated unilateral mydriasis without accompanying neurological abnormalities is rare, it has occasionally been associated with nebulizer use. We aimed to quantitatively assess pupillary changes using a pupillometer in cases of isolated mydriasis, which has not been described in previous studies.Methods: We retrospectively analyzed patients who developed unilateral mydriasis after using an ipratropium bromide nebulizer using a prospectively collected dat
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AKÇA, Hatice Şeyma, Mehmet Muzaffer İSLAM, Uğur Yasin AKGÜN, Serdar ÖZDEMİR, Abdullah ALGIN, and Serkan Emre EROĞLU. "Relationship of inhaled ipratropium and inhaled salbutamol with pupil dilation: A prospective observational study." Journal of Experimental and Clinical Medicine 38, no. 4 (2021): 457–60. http://dx.doi.org/10.52142/omujecm.38.4.10.

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This prospective randomized study aimed to compare the effects of nebulizer drugs on unilateral or bilateral dilation of the pupil that may develop due to mask incompatibility or patient incompatibility in patients receiving inhaled therapy. Following the approval of the local ethics committee, this study was carried out prospectively and observationally in the period from October 1, 2018 to April 1, 2019 in an emergency clinic with an annual capacity of 600,000 patients in a tertiary education and research hospital. The patients were divided into three groups: those given salbutamol alone (20
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Alonso Puig, Mario, Mercedes Alonso-Prieto, Jordi Miró, Raquel Torres-Luna, Diego Plaza López de Sabando, and Francisco Reinoso-Barbero. "The Association Between Pain Relief Using Video Games and an Increase in Vagal Tone in Children With Cancer: Analytic Observational Study With a Quasi-Experimental Pre/Posttest Methodology." Journal of Medical Internet Research 22, no. 3 (2020): e16013. http://dx.doi.org/10.2196/16013.

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Background Patients with secondary pain due to mucositis after chemotherapy require treatment with morphine. Use of electronic video games (EVGs) has been shown to be an effective method of analgesia in other clinical settings. Objective The main objective of this study was to assess the association between the use of EVGs and the intensity of pain caused by chemotherapy-induced mucositis in pediatric patients with cancer. The secondary objective was to assess the association between changes in pain intensity and sympathetic-parasympathetic balance in this sample of pediatric patients. Methods
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López García, Sergio, María Inmaculada Martín Villar, José Antonio Navia Manzano, et al. "La pupilometría en el socorrismo acuático profesional: la vigilancia como factor determinante del ahogamiento (The use of pupillometry in aquatic lifesaving: vigilance as a key factor in drowning)." Retos, no. 36 (January 16, 2019): 571–77. http://dx.doi.org/10.47197/retos.v36i36.67150.

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Una de las causas de muerte significativa en el mundo actual es el ahogamiento por sumersión, la medida preventiva más eficaz es la figura del socorrista acuático, destacando tres funciones principales: prevención, vigilancia e intervención. Un aspecto importante de la vigilancia es el escaneo, siendo escasos los estudios científicos en el método de ejecutarlo. Centrándonos en la disposición psicológica de vigilar, abarca dos acciones entrelazadas: percibir y responder. La percepción es indispensable para la acción, entre ambas está la toma de decisión. Percibiendo, el ojo realiza movimientos
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Zennifa, Fadilla, and Keiji Iramina. "PERUBAHAN UKURAN PUPIL PADA TINGKAT ATENSI." OISAA Journal of Indonesia Emas 4, no. 2 (2021): 40–48. http://dx.doi.org/10.52162/jie.2021.004.02.1.

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Atensi adalah suatu kondisi ketika seseorang berkonsentrasi pada tugas tertentu sambil mengabaikan informasi lainnya. Penelitian pada artikel ini mengusulkan penggunaan pupilometri untuk evaluasi tingkat atensi. Pupilometri didefinisikan sebagai pengukuran perubahan ukuran pupil. Dalam studi ini, tingkat atensi didasarkan atas laporan dari peserta (self assessment) dalam stimulasi yang berdurasi 10 detik. Melalui penelitian ini, didapatkan hasil bahwa ukuran pupil menunjukkan tidak ada perbedaan signifikan di permulaan 6 detik stimulasi (P=0.4776), P>0.05. Perbedaan signifikan terjadi pada
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Popa, Abbie M., Joshua R. Cruz, Ling M. Wong, et al. "Seeing Eye to Eye With Threat: Atypical Threat Bias in Children With 22q11.2 Deletion Syndrome." American Journal on Intellectual and Developmental Disabilities 124, no. 6 (2019): 549–67. http://dx.doi.org/10.1352/1944-7558-124.6.549.

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Abstract Individuals with 22q11.2 deletion syndrome (22q11DS) show high rates of anxiety associated with their increased risk of developing schizophrenia. Biased attention is associated with anxiety and is important to investigate in those with 22q11DS given this association. We analyzed attention bias to emotional faces in 7- to 17-year olds with 22q11DS and typically developing controls (TD) using a dot probe threat bias paradigm. We measured response time, eye tracking, and pupilometry. Those with 22q11DS showed no significant changes in early versus late trials, whereas those who were TD s
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18

Simion, C., and S. Shimojo. "How Early Does the Brain "Know" What It Likes? Evidence from Pupilometry." Journal of Vision 4, no. 8 (2004): 103. http://dx.doi.org/10.1167/4.8.103.

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WAHYUDI, CELINE GABRIELLA, LUKAS LUKAS, and NOVA EKA BUDIYANTA. "Pupilometri Dinamis untuk Mengukur Respons Pupil sebagai Pendeteksi Dini Demensia pada Lansia." ELKOMIKA: Jurnal Teknik Energi Elektrik, Teknik Telekomunikasi, & Teknik Elektronika 11, no. 3 (2023): 553. http://dx.doi.org/10.26760/elkomika.v11i3.553.

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ABSTRAKPupilometri merupakan metode pengukuran respons pupil terhadap stimulus. Kemampuan pupil mata dalam merespons cahaya diamati melalui pupillary light response (PLR). Penelitian mendapati PLR pasien demensia berbeda dengan pasien normal. Penelitian ini bertujuan merancang algoritma computer vision yang dapat mendeteksi pupil secara akurat, menampilkan respons pupil terhadap cahaya dalam bentuk grafik dan PLR pada sebuah aplikasi desktop, yang mengendalikan goggles berisi rangkaian kamera, pencahayaan, dan sensor jarak VL53L0X. Rekaman diproses dengan Local Binary Pattern (LBP) dan deteksi
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Llana, Borano, Alisa Baron, Kushas Khadka, Yusra Suhail, and Shaun Wallace. "Typography and Pupilometry: Exploring the Speed, Comprehension, and Concentration Trade-Off in Reading." Journal of Vision 25, no. 9 (2025): 2470. https://doi.org/10.1167/jov.25.9.2470.

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21

Price, Rebecca B., Greg J. Siegle, Jennifer S. Silk, et al. "SUSTAINED NEURAL ALTERATIONS IN ANXIOUS YOUTH PERFORMING AN ATTENTIONAL BIAS TASK: A PUPILOMETRY STUDY." Depression and Anxiety 30, no. 1 (2012): 22–30. http://dx.doi.org/10.1002/da.21966.

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22

Al-Aidroos, N., K. Ho, and J. Pratt. "Attentional control settings affect attention but not perception: A study of gaze cues and pupilometry." Journal of Vision 8, no. 6 (2010): 137. http://dx.doi.org/10.1167/8.6.137.

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23

Fotiou, D. F., V. Kosta, and S. I. Baloyannis. "Pupilometry as a useful functional procedure for differential diagnosis of Alzheimer's disease and vascular dementia." Journal of the Neurological Sciences 283, no. 1-2 (2009): 265. http://dx.doi.org/10.1016/j.jns.2009.02.104.

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López-De-Audícana-Jimenez-De-Aberasturi, Yolanda, Ana Vallejo-De-La-Cueva, and Naiara Parraza-Diez. "Behavioral pain scales, vital signs, and pupilometry to pain assessment in the critically ill patient: A cross sectional study." Clinical Neurology and Neurosurgery 247 (December 2024): 108644. http://dx.doi.org/10.1016/j.clineuro.2024.108644.

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Kamal, Abdulkadir, Yohan Kim, Amber Salter, Shripal Gunna, Emerson B. Nairon, and DaiWai M. Olson. "There Is Significant Within-Subject Variation in the Time from Light Stimulus to Maximum Pupil Constriction Among Healthy Controls." Journal of Clinical Medicine 13, no. 23 (2024): 7451. https://doi.org/10.3390/jcm13237451.

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Background: Handheld quantitative pupilometers (QPs) measure each phase of the pupillary light reflex (PLR) and provide a summary score based on these values. One phase of the PLR is the period of time from the onset of light exposure to the maximum constriction of the pupil, also known as time to maximum constriction (tMC). Although tMC has been found to vary significantly among patients with neurological injury, there are no studies reporting tMC in healthy controls. This study addresses this gap. Methods: Subjects in this prospective observational study were healthy controls who provided pa
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Albab, Ahmad Ulil, Nur Surya Wirawan, Ratnawati, Syafri Kamsul Arif, Alamsyah Ambo Ala Husain, and Andi Adil. "Perbandingan Efek Antinosiseptif Isoflurane dan Sevoflurane Berdasarkan Refleks Dilatasi Pupil dan Kadar Norepinefrin dengan Menggunakan Konsentrasi Minimum Alveolar 1.0." Majalah Anestesia & Critical Care 43, no. 1 (2025): 53–65. https://doi.org/10.55497/majanestcricar.v43i1.369.

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Latar Belakang: Tantangan yang dihadapi berkaitan dengan penggunaan anestesi umum adalah dalam melakukan penilaian nyeri pada pasien yang tidak sadar. Refleks dilatasi pupil merupakan penilaian stimulasi berbahaya dan efek analgesik di bawah anestesi inhalasi. Diameter pupil juga dinyatakan sebagai ukuran kadar norepinefrin. Belum ada penelitian yang mengkaji perbandingan efek antinosiseptif antara isoflurane dan sevoflurane yang diukur dengan refleks dilatasi pupil dan kadar norepinefrin di bawah konsentrasi minimum alveolar yang ekuivalen. Tujuan penelitian ini adalah untuk mengetahui perban
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Bezdetko, Pavlo, and Rada Parkhomets. "PREDICTING THE EFFECTIVENESS OF MYOPIA CONTROL WHEN USING ORTHOKERATOLOGICAL LENSES BASED ON INDIVIDUAL EYE PARAMETERS." Inter Collegas 9, no. 1 (2022): 76–85. http://dx.doi.org/10.35339/ic.9.1.76-85.

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Introduction. The prevalence and progressive course of myopia is one of the most important medical and social problems worldwide. In recent years, in our country and abroad there is a tendency to increase the incidence of myopia, becoming in some countries an epidemic. In recent years, the most common method of effective control of myopia is the method of refractive therapy with orthokeratological lenses. Objective: To develop criteria for predicting the effectiveness of myopia control using orthokeratological lenses based on individual eye parameters. Object and methods of research. A total o
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Kotani, Joji, Hiroyuki Nakao, Isamu Yamada, Atsushi Miyawaki, Naomi Mambo, and Yuko Ono. "A Novel Method for Measuring the Pupil Diameter and Pupillary Light Reflex of Healthy Volunteers and Patients With Intracranial Lesions Using a Newly Developed Pupilometer." Frontiers in Medicine 8 (September 7, 2021). http://dx.doi.org/10.3389/fmed.2021.598791.

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Background: Physicians currently measure the pupil diameter and the pupillary light reflex with visual observations using a ruler and a traditional penlight, leading to possibly inaccurate and subjective assessments. Although a mobile pupillometer has been developed and is available in clinical settings, this device can only assess one pupil at a time. Hence, an indirect pupillary light reflex, including those under irradiation to the opposite side of pupil, cannot be evaluated. Consequently, we have developed a new automatic mobile pupilometer, the Hitomiru®, with Hitomiru Co., Ltd. (Tokyo, J
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Dasman, Albina Vilia Fera, Soraya Arifin, Irwandi Rachman, and Andri Senoja. "Gambaran Hasil Pengukuran Pupil Distance Menggunakan Pupilometer Digital, PD Meter Manual dan PD Meter Aplikasi." RS Mata Makassar: Journal of Ophthalmology 1, no. 1 (2024). https://doi.org/10.63670/mata.v1i1.26.

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This allows light to enter the eyeball and hit the retina. Thus, the pupil appears black because the light entering the eyeball is absorbed by the retina. The purpose of the study was to determine the description of the results of measuring the pupil distance using a manual PD meter, a PD meter, a GlassifyMe application with a pupilometer. The location of the study was at the Makassar Eye Hospital. The results of the Pupil Distance measurement study using a digital Pupilometer, a manual PD meter, and the GlassifyMe PD meter application were obtained from 70 patients at the Makassar Eye Hospita
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Chacko, Ruhel K., Prithvi Chandrakanth, Aniket Roy, Hirika Gosalia, Gargi Aggarwal, and V. Narendran. "Pupilmate: A do-it-yourself frugal pupilometer." Indian Journal of Ophthalmology, December 27, 2024. https://doi.org/10.4103/ijo.ijo_859_24.

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Abstract The pupillary direct and consensual reflex is an important non-invasive quick assessment of the neurological state of the eye. Currently, there is no cheap and affordable recording tool for screening and documentation of a relative afferent pupillary defect. We describe how to construct a frugal, do-it-yourself handheld scotopic binocular pupillometer device called Pupilmate. Two simple Wi-Fi-enabled board cameras fitted on both sides of the back of a rectangular cardboard box separated by a central paper divider, one side of the rectangular box was left open. An infrared red (IR) lig
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"Objective Measurement of Sustained Pupillary Constriction: A Pilot Study Using an App-Based Pupilometer." Vision Development & Rehabilitation, March 30, 2020, 57–63. http://dx.doi.org/10.31707/vdr2020.6.1.p57.

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Background: The pupillary reaction is controlled by the two main branches of the autonomic nervous system, namely the parasympathetic and sympathetic nervous systems. New discoveries in pupil research has identified that intrinsically photosensitive retinal ganglion cells have an impact on pupillary constriction, particularly sustained pupillary constriction. In the current paper, an objective measurement of sustained pupillary constriction versus the inability to maintain sustained pupillary constriction are observed. The variability in the sustained pupillary constriction, i.e. Alpha Omega p
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Martín-Rodríguez, Francisco, Rafael Martín-Sánchez, Carlos del Pozo Vegas, et al. "Pupilometer efficacy in monitoring anxiety in undergraduate medical students during high-fidelity clinical simulation." Scientific Reports 15, no. 1 (2025). https://doi.org/10.1038/s41598-025-95290-6.

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Murphy, Róisín, Alan Rankin, Pooler Archbold, and Chris Bleakley. "Pupillary Light Reflex Metrics as an Objective Biomarker for Sport-Related Concussion in Elite Field Hockey." Journal of Science in Sport and Exercise, August 8, 2024. http://dx.doi.org/10.1007/s42978-024-00293-w.

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Abstract Background Concussion diagnosis is based on subjective assessment of several nonspecific clinical signs and symptoms with no objective test to aid in diagnosis. The pupillary system, in particular the pupil light reflexes (PLR) has attracted plausible consideration in this area, given its complex neural circuitry and autonomic function. Aim To assess the reliability and validity of using the NeurOptics PLR-3000 pupilometer to measure PLR, and to determine normative data for female athletes. Methods A cross sectional cohort study of 33 senior elite female field hockey athletes (aged 19
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Reidy, Marielle G., Andrew T. E. Hartwick, and Donald O. Mutti. "The association between pupillary responses and axial length in children differs as a function of season." Scientific Reports 14, no. 1 (2024). http://dx.doi.org/10.1038/s41598-024-51199-0.

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AbstractThe association between pupillary responses to repeated stimuli and adult refractive error has been previously demonstrated. This study evaluated whether this association exists in children and if it varies by season. Fifty children aged 8–17 years (average: 11.55 ± 2.75 years, 31 females) with refractive error between + 1.51 and − 5.69 diopters (non-cycloplegic) participated (n = 27 in summer, and n = 23 in winter). The RAPDx pupilometer measured pupil sizes while stimuli oscillated between colored light and dark at 0.1 Hz in three sequences: (1) alternating red and blue, (2) red-only
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Rickmann, A., M. Waizel, S. Kazerounian, P. Szurman, and KT Boden. "Relation of Pupil Size and retinal diseases." August 9, 2016. https://doi.org/10.19070/2332-290X-1600050.

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Purpose: The aim of this study was to evaluate differences in pupil size of subjects with diabetes mellitus, age-related macular degeneration and retinal vein occlusion at different illumination levels with a novel pupilometer. Methods: The pupil size of study participants was measured with an infrared-video pupillometer (PupilX, Albomed) at 5 different illumination levels (0, 0.5, 4, 32 and 250 lux). Measurements were performed by the same investigator. 90 images were executed during a measurement period of 3 seconds. Results: This cross-sectional study analysed 484 eyes of 242 patients with
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de Havenon, Adam H., Melissa Cortez, Cecilia Peterson, Fa Tuuhetaufa, Nils Petersen, and Ka-Ho Wong. "Abstract TMP97: Autonomic Nervous System Dysfunction Correlates With Increased Blood Pressure Variability After Acute Ischemic, But Not Hemorrhagic, Stroke." Stroke 51, Suppl_1 (2020). http://dx.doi.org/10.1161/str.51.suppl_1.tmp97.

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Background: Elevated blood pressure variability (BPV) in the days after acute stroke onset is associated with worse outcome. However, the mechanism of increased BPV remains unknown, but may be due to dysfunction of the autonomic nervous system, which can be measured by pupil response to a light stimulus. Methods: This is a retrospective study of 109 patients in a neurocritical care unit: 45 with acute ischemic stroke (AIS), 44 with intracerebral hemorrhage (ICH), and 20 with subarachnoid hemorrhage (SAH). The primary outcome is BPV, measured as standard deviation of SBP (SD), using all blood p
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Matsui, Takayoshi, Kazuhiro Hara, Makoto Iwata, et al. "Cervical muscle stiffness and parasympathetic nervous system improvements for treatment-resistant depression." BMC Musculoskeletal Disorders 23, no. 1 (2022). http://dx.doi.org/10.1186/s12891-022-05860-2.

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Abstract Background Although treatment-resistant depression (TRD) is a major public health problem that increases mortality due to suicides, a considerable percentage of patients do not respond adequately to variable treatments. Patients with TRD sometimes have comorbid cervical stiffness. This observational study aims to examine the association of local modulation of cervical muscles with TRD and to learn the involvement of the parasympathetic nervous system in the underlying mechanism. Methods A total of 1103 hospitalized patients with TRD who were resistant to outpatient care were enrolled
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Samiksha Lalsare, Sattyam Wankhade, Arun Khalikar, Suryakant Deogade, and Archit Kapadia. "A Precise Iris Positioning Technique Using a Modified Occlusal Plane Analyser - A Case Report." Journal of Evolution of Medical and Dental Sciences, June 29, 2024, 98–101. http://dx.doi.org/10.14260/jemds.v13i4.609.

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The eye is a vital organ, a key aspect of facial expression and the essence of cosmetic appearance in human beings.[1] Surgical intervention and removal of the eyeball may be required due to accidental trauma, pathology or congenital defects.[2] The disfigurement associated with the loss of an eye can cause immense physical, psychosocial and emotional disturbance.[3] The surgery involved can vary from minimal surgical intervention, such as evisceration or enucleation, to extensive radical treatment, such as exenteration.[4] The associated psychological distress can be reduced by timely rehabil
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Cui, Lipu, Ying Xiao, Zhaoyu Xiang, Zhangling Chen, Chenhao Yang, and Haidong Zou. "Study on the correlation between iris blood flow, iris thickness and pupil diameter in the resting state and after pharmacological mydriasis in patients with diabetes mellitus." BMC Ophthalmology 24, no. 1 (2024). http://dx.doi.org/10.1186/s12886-024-03322-y.

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Abstract Background To investigate whether iris blood flow and iris thickness at the iris smooth muscle region affect the pupil diameter at rest and after drug-induced mydriasis in patients with type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM). Methods T1DM patients and healthy children were recruited from the SCADE cohort. T2DM patients and healthy adults were recruited from patients undergoing cataract surgery at Shanghai General Hospital. Iris vessel density, pupil diameter (PD) and iris thickness were measured in both the resting and drug-induced mydriasis states. Iris v
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Kossel, Clara-Sophie, Franca Kobus, Matthias C. Borutta, et al. "Pupillometry in the follow-up of patients undergoing EVT - prediction of space-occupying hemispheric infarction." Journal of Neurology, June 10, 2023. http://dx.doi.org/10.1007/s00415-023-11797-w.

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Abstract Background Despite benefits of endovascular treatment (EVT) for large vessel occlusion (LVO) ischemic stroke, space-occupying brain edema (BE) represents a detrimental complication. In critical-care settings, CT-imaging is needed for monitoring these patients. Yet, bed-side techniques with the potential to predict whether patients develop BE or not would facilitate a time- and cost-efficient patient care. We assessed clinical significance of automated pupillometry in the follow-up of patients undergoing EVT. Methods From 10/2018 to 10/2021, neurocritical-care-unit patients were retros
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GAJARDO, ABRAHAM I. J., DANIELA B. SANDOVAL, RODRIGO VIDAL, et al. "1810-LB: Diagnostic Accuracy of Automated Pupillometry for Diabetic Retinopathy Screening." Diabetes 73, Supplement_1 (2024). http://dx.doi.org/10.2337/db24-1810-lb.

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Introduction: Diabetic retinopathy (DR) is a major and preventable cause of blindness. Although regular fundoscopic examination (FE) is recommended to detect DR, screening coverage remains low in Latin America, the USA, and other regions, supporting the need for new screening tools. Because pupillary reactivity to a short light stimulus is decreased in patients with DR, this study aimed to assess the diagnostic accuracy of automated pupillometry (AP), an inexpensive tool, for DR screening in type diabetes mellitus (T2DM) patients. Methods: Diagnostic accuracy study performed prospectively in 9
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Piedad, Elizabeth Acurio Padilla, Yamilex Reascos Chalacán Melany, and Fernando Enrríquez Grijalva Mauricio. "Sistema de recomendaciones para la clasificación de Pupilometría en el traumatismo craneoencefálico grave." April 1, 2025. https://doi.org/10.5281/zenodo.15200558.

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El traumatismo craneoencefálico es una lesión compleja que puede generar complicaciones y secuelas neurológicas severas, incluso mortales. Por esta razón, la evaluación multimodal de los pacientes con TCE es esencial para garantizar un tratamiento oportuno y personalizado. En el contexto del traumatismo craneoencefálico grave, la pupilometría es una técnica de medición del tamaño y la reactividad pupilar, constituye una herramienta adicional para su manejo, ya que permite monitorizar el estado neurológico y predice su
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Rouche, O., A. Wolak-Thierry, Q. Destoop, et al. "Evaluation of sedation using pupilometry in ICUs: a pilot study." Critical Care 16, S1 (2012). http://dx.doi.org/10.1186/cc10936.

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Bachtiar Amin, Fauzan, Alamsyah A.A Husain, Andi Muhammad Takdir Musba, and Muh Ramli Ahmad. "Perbandingan Remifentanil Kontinu 0.15 Mcg/Kgbb dengan Fentanyl 3 Mcg/Kgbb pada Intubasi Endotrakeal Diukur Menggunakan Pupillometer (AlgiScan®)." Nusantara Medical Science Journal, April 5, 2021, 71–79. http://dx.doi.org/10.20956/nmsj.v5i2.9912.

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Introduction: All opioids have varying levels of sedative effects with increasing dosages, although with different strengths. Therefore, the opioid component as a sedative regiment is usually maintained at minimum dose for adequate analgesic with regard to patient comfort. Along with the progress of knowledge, parameters have been found to measure the level of analgesic and sedative. Methods: The principle of measurement is done by using the diameter of pupil and then analyzed through AlgiScan and compared to certain standards. The using of pupilometers AlgiScan in assessing the level of sedat
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Pulcu, Erdem, and Michael Browning. "Affective bias as a rational response to the statistics of rewards and punishments." eLife 6 (October 4, 2017). http://dx.doi.org/10.7554/elife.27879.

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Affective bias, the tendency to differentially prioritise the processing of negative relative to positive events, is commonly observed in clinical and non-clinical populations. However, why such biases develop is not known. Using a computational framework, we investigated whether affective biases may reflect individuals’ estimates of the information content of negative relative to positive events. During a reinforcement learning task, the information content of positive and negative outcomes was manipulated independently by varying the volatility of their occurrence. Human participants altered
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LOPEZ, DE AUDICANA YOLANDA, de la Cueva Ana Vallejo, and Diez Naiara Parraza. "Behavioral pain scales, vital signs, and pupilometry to pain assessment in the critically ill patient: A cross sectional study." Clinical Neurology and Neurosurgery 247 (2024) 108644 (November 18, 2024). https://doi.org/10.1016/j.clineuro.2024.108644.

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Barry, Colin, and Edward Wang. "Racially fair pupillometry measurements for RGB smartphone cameras using the far red spectrum." Scientific Reports 13, no. 1 (2023). http://dx.doi.org/10.1038/s41598-023-40796-0.

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AbstractPupillometry is a measurement of pupil dilation commonly performed as part of neurological assessments. Prior work have demonstrated the potential for pupillometry in screening or diagnosing a number of neurological disorders including Alzheimer’s Disease, Schizophrenia, and Traumatic Brain Injury. Unfortunately, the expense and inaccessibility of specialized pupilometers that image in the near infrared spectrum limit the measurement to high resource clinics or institutions. Ideally, this measurement could be available via ubiquitous devices like smartphones or tablets with integrated
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Turkoglu, Ceren, Feyza Okyaz, and Elif Arslan. "The Relationship Between ADHD and Autonomic Regulation: a Pupillometry-Based Study." Bratislava Medical Journal, May 26, 2025. https://doi.org/10.1007/s44411-025-00185-7.

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Abstract Background It has recently been suggested that Attention-deficit hyperactivity disorder (ADHD) may also be associated with autonomic dysfunction, but the underlying mechanisms that alter autonomic regulation are still unknown. The aim of the study was to investigate the relationship between ADHD and autonomic dysfunction using data obtained via automated pupillometry, which is a noninvasive, easily repeatable, and objective test. Methods In total, 70 patients diagnosed with Attention-deficit hyperactivity disorder by the same doctor as a child psychiatrist were referred to as Group I.
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