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Relevant bibliographies by topics / Purine catabolism

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Academic literature on the topic 'Purine catabolism'

Author: Grafiati

Published: 10 December 2022

Last updated: 28 January 2023

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Journal articles on the topic "Purine catabolism"

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Tomlinson, Patricia Tolson, and Carol J. Lovatt. "Nucleotide Metabolism in ‘Washington’ Navel Orange Fruit: I. Pathways of Synthesis and Catabolism." Journal of the American Society for Horticultural Science 112, no. 3 (1987): 529–35. http://dx.doi.org/10.21273/jashs.112.3.529.

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Abstract The capacity of ‘Washington’ navel orange fruit [Citrus sinensis (L.) Osbeck] to synthesize and catabolize purines and pyrimidines was assessed. De novo biosynthesis of purine nucleotide was demonstrated by [14C] bicarbonate incorporation into purine nucleotides, blockage of this process by four known inhibitors, and assimilation of radiolabeled carbon from formate, both carbons of glycine, and carbon-3 of serine into the adenine ring. De novo synthesis of pyrimidines via the orotate pathway in young fruit was demonstrated by incorporation of [14C] bicarbonate and [6-14C]orotic acid i

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Xi, Hualin, Barbara L. Schneider, and Larry Reitzer. "Purine Catabolism in Escherichia coliand Function of Xanthine Dehydrogenase in Purine Salvage." Journal of Bacteriology 182, no. 19 (2000): 5332–41. http://dx.doi.org/10.1128/jb.182.19.5332-5341.2000.

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ABSTRACT Escherichia coli is not known to utilize purines, other than adenine and adenosine, as nitrogen sources. We reinvestigated purine catabolism because a computer analysis suggested several potential ς54-dependent promoters within a 23-gene cluster whose products have homology to purine catabolic enzymes. Our results did not provide conclusive evidence that the ς54-dependent promoters are active. Nonetheless, our results suggest that some of the genes are metabolically significant. We found that even though several purines did not support growth as the sole nitrogen source, they did stim

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Sun, Runbin, Jingqiu Huang, Na Yang, et al. "Purine Catabolism Shows a Dampened Circadian Rhythmicity in a High-fat Diet-Induced Mouse Model of Obesity." Molecules 24, no. 24 (2019): 4524. http://dx.doi.org/10.3390/molecules24244524.

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High-calorie diet, circadian rhythms and metabolic features are intimately linked. However, the mediator(s) between nutritional status, circadian rhythms and metabolism remain largely unknown. This article aims to clarify the key metabolic pathways bridging nutritional status and circadian rhythms based on a combination of metabolomics and molecular biological techniques. A mouse model of high-fat diet-induced obesity was established and serum samples were collected in obese and normal mice at different zeitgeber times. Gas chromatography/mass spectrometry, multivariate/univariate data analyse

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Yin, Yuling, Riko Katahira, and Hiroshi Ashihara. "Metabolism of Purine Alkaloids and Xanthine in Leaves of Maté (Ilex paraguariensis)." Natural Product Communications 10, no. 5 (2015): 1934578X1501000. http://dx.doi.org/10.1177/1934578x1501000503.

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Accumulation and metabolism of purine alkaloids in leaves of maté ( Ilex paraguariensis) were investigated. In winter, leaves accumulated caffeine but not theobromine, indicating that caffeine is the end product of purine alkaloid synthesis in maté. To elucidate the purine alkaloid metabolism in maté leaves, the metabolic fate of [8-14C]theobromine, [8-14C]theophylline, [8-14C]caffeine and [8-14C] xanthine was investigated in the leaf disks of young and mature leaves. In young maté leaves, significant amounts of theobromine and theophylline were utilized for caffeine biosynthesis, but the conv

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Muzychka, Oksana, Olexandr Kobzar, Oleg Shablykin, Volodymyr Brovarets, and Andriy Vovk. "5-Substituted N-(9H-purin-6-yl)-1,2-oxazole-3-carboxamides as xanthine oxidase inhibitors." Ukr. Bioorg. Acta 2020, Vol. 15, N1 15, no. 1 (2020): 20–25. http://dx.doi.org/10.15407/bioorganica2020.01.020.

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Synthetic 6-substituted purine derivatives are known to exhibit diverse bioactivity. In this paper, a series of N-(9H-purin-6-yl)-1,2-oxazole-3-carboxamide derivatives were synthesized and evaluated in vitro against xanthine oxidase, an enzyme of purine catabolism. The introduction of aryl substituent at position 5 of the oxazole ring was found to increase the inhibition efficiency. Some of the inhibitors containing 5-substituted isoxazole and purine moieties were characterized by IC50 values in the nanomolar range. According to the kinetic data, the most active N-(9H-purin-6-yl)-5-(5,6,7,8-te

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Itakura, M., N. Maeda, and K. Yamashita. "Increased rate of purine biosynthesis in rat liver after bilateral adrenalectomy." American Journal of Physiology-Endocrinology and Metabolism 251, no. 4 (1986): E373—E378. http://dx.doi.org/10.1152/ajpendo.1986.251.4.e373.

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In bilaterally adrenalectomized rat liver the increased rate of de novo purine synthesis was shown by the increased [14C]glycine incorporation into hepatic acid-soluble purines with unchanged rapidly miscible glycine pool size and its turnover rate and by the increased rate of chasing of radiolabeled purines. At 24 h after adrenalectomy, the rate of de novo purine synthesis increased by 70%, 5-phosphoribosyl-1-pyrophosphate (PRPP) content increased by 200%, the specific activity of amidophosphoribosyltransferase (EC 2.4.2. 14; ATase) did not change, ATP and GTP showed a 33 and 24% decrease, an

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Pizzichin, M., M. L. Pandolfi, L. Terzuoli, L. Arezzini, and R. Pagani. "Purine nucleotide catabolism in rat liver." Biochemical Society Transactions 21, no. 2 (1993): 189S. http://dx.doi.org/10.1042/bst021189s.

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HADANO, SHINJI, SATOSHI SAKAI, MASASHI OGASAWARA, and AKIRA ITO. "EFFECTS OF EXERCISE INTENSITY ON PURINE CATABOLISM." Japanese Journal of Physical Fitness and Sports Medicine 37, no. 3 (1988): 225–33. http://dx.doi.org/10.7600/jspfsm1949.37.225.

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Felici, C., I. Ciari, L. Terzuoli, et al. "Purine Catabolism in Advanced Carotid Artery Plaque." Nucleosides, Nucleotides and Nucleic Acids 25, no. 9-11 (2006): 1291–94. http://dx.doi.org/10.1080/15257770600890772.

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Voloshchuk, Oksana, Halyna Kopylchuk, and Andriana Plytus. "Activity of purine nucleotide catabolic enzymes in the liver of rats under conditions of nutritional imbalance." Biolohichni systemy 12, no. 2 (2020): 119–24. http://dx.doi.org/10.31861/biosystems2020.02.119.

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The aim of the study was to investigate the activity of purine nucleotide catabolism enzymes, in particular, AMP-deaminase, 5'-nucleotidase, guanosine deaminase, and guanosine phosphorylase and xanthine oxidase in the cytosolic fraction of the liver of rats under conditions of different dietary supply of sucrose and dietary proteins. Enzyme activity was determined by photo colorimetric method: AMP-deaminase activity by the amount of ammonia formed by deamination of AMP, which has a maximum absorption at λ-540 nm and 5'-nucleotidase activity by the amount of Pn formed by hydrolysis of AMP at λ-

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Dissertations / Theses on the topic "Purine catabolism"

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Le, Tissier Paul Roussel. "The biochemical genetics of purine catabolism in mice." Thesis, University of Reading, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.236393.

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Kavianipour, Mohammad. "Myocardial energy metabolism in ischemic preconditioning, role of adenosine catabolism." Doctoral thesis, Umeå University, Public Health and Clinical Medicine, 2002. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-14.

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<p>Brief episodes of ischemia and reperfusion render the myocardium more resistant to necrosis from a subsequent, otherwise lethal ischemic insult. This phenomenon is called ischemic preconditioning(IP). Today, much is known about the signalling pathways involved in IP; however, the details of the final steps leading to cardioprotection, remain elusive. Adenosine (a catabolite of ATP) plays a major role in the signalling pathways of IP. Following IP there is an unexplained discrepancy between an increased adenosine production (evidenced by increased 5’-nucleotidase activity) and the successive

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Baccolini, Chiara [Verfasser]. "Analysis of in vivo purine nucleotide catabolism in Arabidopsis thaliana with focus on nucleoside hydrolase 2 / Chiara Baccolini." Hannover : Gottfried Wilhelm Leibniz Universität Hannover, 2019. http://d-nb.info/1193177146/34.

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Huynh, Hanh Kim. "Physiological, ultrastructural and cytochemical studies on the utilization of various intermediates of the purine catabolism pathway as sole sources of nitrogen by marine phytoplankters." Thesis, University of British Columbia, 1989. http://hdl.handle.net/2429/27491.

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Eleven species of marine microalgae belonging to six different taxonomic divisions were tested for their ability to grow on allantoin, allantoic acid, hypoxanthine and urea as sole sources of nitrogen. All species were able to utilize the nitrogen atoms of urea but only six of these were able to grow on allantoic acid, while five showed moderate to good growth in hypoxanthine. None was able to utilize allantoin. The study of nickel requirements for the growth of these microalgae on the different sources of nitrogen, together with the results of inhibitor tests suggest that those species capabl

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Lee, Hakjoo. "Nitrogen regulation of the purine catabolic genes in Neurospora crassa /." The Ohio State University, 1990. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487681148541111.

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6

Cecchetto, Gianna. "Catabolisme de purines chez Aspergillus nidulans : caractérisation du transporteur AzgA : analyse de la fixation à l'ADN de l'activateur transcriptionnel UaY." Paris 11, 2003. http://www.theses.fr/2003PA112331.

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Chez Aspergillus nidulans, au moins trois perméases sont impliquées dans le transport des purines. AzgA transporte l’hypoxanthine et l’adénine. UapA transporte l’acide urique et la xanthine. UapC est une perméase mineure qui transporte toutes ces purines. L’expression des gènes uapA et uapC est induite en présence d’acide urique par l’intermédiaire de la protéine UaY et réprimée en présence d’ammonium du fait de l’inactivation de l'activateur transcriptionnel AreA. Ce travail présente la caractérisation du gène azgA et de la protéine qu’il code. AzgA définit un sous-groupe de transporteurs app

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RIBARD, CARIN. "Etude de la regulation du catabolisme des purines chez aspergillus nidulans : - clonage et caracterisation moleculaire de oxpa. - caracterisation moleculaire de nada." Paris 11, 1999. http://www.theses.fr/1999PA112379.

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Chez aspergillus nidulans, l'expression des genes de structure du catabolisme des purines est induite en presence d'acide urique et reprimee en presence d'ammonium et de glutamine. Deux activateurs controlent l'expression de ces genes de structure : uay, un activateur a complexe binucleaire a zinc, specifique a cette voie, et area, un facteur gata implique dans la repression generale par l'azote. Le gene nada code pour la premiere enzyme du catabolisme des purines, une adenine deaminase. Nada a precedemment ete clone et sequence par n. Oestreicher. Ce travail presente la caracterisation molecu

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OESTREICHER, NATHALIE. "Etude moleculaire de la regulation du catabolisme des purines chez aspergillus nidulans : caracterisation du gmene de l'urate oxydase. analyse fonctionnelle du regulateur positif." Paris 11, 1991. http://www.theses.fr/1991PA112276.

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L'urate oxydase d'aspergillus nidulans, codee par le gene uaz, est une proteine de 319 acides amines. Elle presente une homologie de 36% avec l'urate oxydase de rat. La comparaison avec sept autres urates oxydases a mis en evidence la conservation du site potentiel de fixation du cuivre et du signal putatif d'entree dans les peroxysomes. Une analyse par northern de l'expression du gene uaz a confirme que ce gene est inductible par l'acide 2-thiourique (analogue de l'inducteur naturel: l'acide urique) et repressible par l'ammonium. L'induction et une partie du niveau de base du gene uaz ont bes

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Casartelli, Alberto. "Purine Catabolism in Wheat: Source of Nutrients and Protective Metabolites." Thesis, 2018. http://hdl.handle.net/2440/123271.

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Purine catabolism is known to have a dual function in recycling nitrogen (N) and carbon (C) atoms present in the heterocyclic purine ring and participating in stress signalling through the stimulation of ABA metabolism by allantoin, an intermediate in the pathway. However, little information was available of the functions in cereals and, in particular, bread wheat. The aims of this PhD thesis was to investigate the role of purine catabolism and allantoin in Australian bread wheat (Triticum aestivum) genotypes (RAC875 and Mace) grown under N deficiency and water deficit. Firstly, the purine cat

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Book chapters on the topic "Purine catabolism"

1

Cohen, Amos, and Jerzy Barankiewicz. "Purine Ribonucleotide and Deoxyribonucleotide Catabolism in Lymphocytes." In Purine and Pyrimidine Metabolism in Man V. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4684-5104-7_94.

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Terzuoli, Lucia, Maria Pizzichini, Anna Di Stefano, Brunetta Porcelli, Antonella Tabucchi, and Roberto Pagani. "Purine Nucleotide Catabolism in Rat Liver After Castration." In Advances in Experimental Medicine and Biology. Springer US, 1991. http://dx.doi.org/10.1007/978-1-4899-2638-8_67.

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Bontemps, F., G. Van den Berghe, and H. G. Hers. "Pathways of Adenine Nucleotide Catabolism in Human Erythrocytes." In Purine and Pyrimidine Metabolism in Man V. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4684-1248-2_53.

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Schopf, Gerhard, Michael Havel, Roland Fasol, and Mathias M. Müller. "Enzyme Activities of Purine Catabolism and Salvage in Human Muscle Tissue." In Purine and Pyrimidine Metabolism in Man V. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4684-1248-2_78.

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Barankiewicz, Jerzy, and Amos Cohen. "Ethanol Induced Nucleotide Catabolism in Mouse T Lymphoblastoid Cells in Vitro." In Purine and Pyrimidine Metabolism in Man V. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4684-1248-2_34.

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Helland, S., and P. M. Ueland. "Determination of S-Adenosylhomocysteine in Tissues Following Pharmacological Inhibition of S-Adenosylhomocysteine Catabolism." In Purine and Pyrimidine Metabolism in Man V. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4684-1248-2_103.

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van Waeg, Geert, Frank Niklasson, and Carl-Henric de Verdier. "Deamination of Guanine to Xanthine: A Metabolic Pathway of Underestimated Importance in Human Purine Catabolism?" In Purine and Pyrimidine Metabolism in Man V. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4684-5104-7_70.

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Kather, H. "Beta Adrenergic Receptor Mediated Stimulation of Adenine Nucleotide Catabolism and Purine Release in Human Adipocytes." In Purines in Cellular Signaling. Springer New York, 1990. http://dx.doi.org/10.1007/978-1-4612-3400-5_20.

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Wortmann, Robert L., Judith A. Veum, and John W. Rachow. "Purine Catabolic Enzymes in Human Synovial Fluids." In Advances in Experimental Medicine and Biology. Springer US, 1989. http://dx.doi.org/10.1007/978-1-4684-5673-8_64.

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10

Gojkovic, Zoran, Silvia Paracchini, and Jure Piskur. "A New Model Organism for Studying the Catabolism of Pyrimidines and Purines." In Advances in Experimental Medicine and Biology. Springer US, 1998. http://dx.doi.org/10.1007/978-1-4615-5381-6_94.

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