Log in

Relevant bibliographies by topics / Purine compounds / Dissertations / Theses

To see the other types of publications on this topic, follow the link: Purine compounds.

Dissertations / Theses on the topic 'Purine compounds'

Author: Grafiati

Published: 7 September 2021

Last updated: 29 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 30 dissertations / theses for your research on the topic 'Purine compounds.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.

1

Potgieter, Wilna. "An investigation of the possible anticancer activity of seven novel bi(amido) gold(I) complexes derived from a purine or azole base." Diss., Pretoria : [s.n.], 2009. http://upetd.up.ac.za/thesis/available/etd-09112009-155357/.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Geremia, Kara L. "Computational Estimation of the pKa's of Purines and Related Compounds." Wright State University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=wright1449754930.

Full text

APA, Harvard, Vancouver, ISO, and other styles

3

Collicott, Roland. "Investigation of chiral silicon compounds for the determination of enantiomeric purity." Thesis, n.p, 2001. http://ethos.bl.uk/.

Full text

APA, Harvard, Vancouver, ISO, and other styles

4

Lemin, David. "Synthèse d'analogues des ligands naturels de récepteurs nicotiniques et purinergiques." Doctoral thesis, Universite Libre de Bruxelles, 2004. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/211158.

Full text

Abstract:

Cette thèse s’inscrit dans le cadre de l’étude de la relation structure-activité d’analogues de ligands naturels de récepteurs nicotiniques et purinergiques. Ce travail se divise en deux parties.<p><p>Dans la première partie de cette thèse, nous avons réalisé la synthèse d’analogues de la 11-homosédinone, alcaloïde isolé de la plante Sedum acre, qui présente une activité agoniste sur différents récepteurs nicotiniques du système nerveux central. Les différents analogues ont été synthétisé par application de la méthoxylation anodique pour introduire succesivement deux substituants en postion 2

APA, Harvard, Vancouver, ISO, and other styles

5

Pedreschi, Romina Paola. "Fractionation of phenolic compounds from a purple corn extract and evaluation of antioxidant and antimutagenic activities." Texas A&M University, 2005. http://hdl.handle.net/1969.1/2343.

Full text

Abstract:

Qualitative and quantitative analysis of anthocyanins and other phenolic compounds from a purple corn extract was performed. The purple corn extract had cyanidin-3-glucoside, pelargonidin-3-glucoside, peonidin-3-glucoside and its respective acylated anthocyanin-glucosides. Cyadinin-3glucoside was the main constituent (44.4 ?? 4.7%) followed by the acylated cyanidin-3-glucoside (26.9 ?? 8.0%). Other phenolic compounds present in the purple corn corresponded to protocatechuic acid, vanillic acid, and p-coumaric acid. In addition, quercetin derivatives, a hesperitin derivative and pcoumaric and f

APA, Harvard, Vancouver, ISO, and other styles

6

Spell, Sarah. "The Study of Au(III) Compounds and their Interaction with Zinc Finger Proteins." VCU Scholars Compass, 2014. http://scholarscompass.vcu.edu/etd/634.

Full text

Abstract:

Gold compounds have been used in medicine dating back as early as 2500 BC. Over the years gold(I) and gold(III) compounds have been used and designed to target rheumatoid arthritis, cancer, and viral diseases. New drug targets have been found for gold compounds that give insight into their mechanisms of action. Here we focus on the synthesis of Au(III) compounds designed to selectively target zinc finger (ZF) proteins. ZF proteins exhibit a variety of functions, including transcription, DNA repair, and apoptosis. Displacement of the central zinc ion, along with mutation of coordinated amino ac

APA, Harvard, Vancouver, ISO, and other styles

7

Al-Deen, Tareq Chemistry Faculty of Science UNSW. "Validation of quantitative nuclear magnetic resonance (QNMR) spectroscopy as a primary ratio analytical method for assessing the purity of organic compounds: a metrological approach." Awarded by:University of New South Wales, 2002. http://handle.unsw.edu.au/1959.4/38328.

Full text

APA, Harvard, Vancouver, ISO, and other styles

8

Raimund, Stefan. "Sources and fluxes of volatile halogenated organic compounds in highly productive marine areas." Brest, 2010. http://www.theses.fr/2010BRES2022.

Full text

Abstract:

Les Composés Halogénés Organiques Volatils (VHOC) sont des composès qui influencent largement la chimie atmosphérique et qui ont des sources naturelles et anthropiques. La production biogénique, les sources marines et les flux à l’interface air-mer de ces composés sont encore peu connues et ont fait l’objet de cette étude. Un système analytique et de nouveaux systèmes de prélèvement ont été développés. Lors d’un travail au laboratoire, il a été démontré que la communication plante-plante orchestre la formation des VHOC : une algue pré-traitée réagit moins intensément après réception d’un signa

APA, Harvard, Vancouver, ISO, and other styles

9

Pradhan, Rajendra Sharad. "Formulation and in vitro release study of poly(DL-lactide) microspheres containing hydrophilic compounds, glycine and its homopeptides." Scholarly Commons, 1992. https://scholarlycommons.pacific.edu/uop_etds/2831.

Full text

Abstract:

In view of current interest in several oligopeptide drugs currently being investigated for controlled implantable delivery, glycine, diglycine, triglycine, tetraglycine and pentaglycine were chosen as model compounds for encapsulation in biodegradable microspheres of DL-polylactide (DL-PLA) by a technique based on oil-in-oil emulsion and the solvent evaporation principle. A DL-polylactide concentration of 10.3% w/w and emulsifier (sorbitan sesquioleate) concentration of 0.3% v/v produced good yields of microspheres with excellent entrapment when processed under following conditions: emulsion t

APA, Harvard, Vancouver, ISO, and other styles

10

Nalla, V. "Synthesis of optically pure pharamaceuticals employing aziridines / epoxides as chiral synthons and development of novel biologically active compounds based on benzopyran -4- ones." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 2018. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/5854.

Full text

APA, Harvard, Vancouver, ISO, and other styles

11

Maroly, Anupam. "The development of a sensitive method to study volatile organic compounds in gaseous emissions of lung cancer cell lines." Texas A&M University, 2005. http://hdl.handle.net/1969.1/2423.

Full text

Abstract:

The ultimate objective of this research was to develop a low cost, reliable system that would lead to early detection of lung cancer. Tests involved the quantitation of gaseous metabolic emissions from immortalized lung cancer cell lines in order to correlate the chemical markers to be of cancerous origin. The specific aims of the project were the study of gas emissions in selected cancer cell lines and identification of volatile organic compounds (VOCs) in them. Disadvantages of earlier studies were that the measurements were not real time or state specific so that molecular identification wa

APA, Harvard, Vancouver, ISO, and other styles

12

Buen, Zachary. "Establishment of gas-phase thermochemical values of various small organic compounds and oligopeptides." Scholarly Commons, 2016. https://scholarlycommons.pacific.edu/uop_etds/262.

Full text

Abstract:

The thesis describes utilizing mass spectrometry and computational methods to study two groups of molecular systems: small organic molecules and oligopeptides. The gas-phase acidities were measured and the structures of the molecular species were calculated. The small molecules investigated included methylparaben, ibuprofen, and triclosan, all known to have some biological activity. The gas-phase acidity measurements made for these small molecules had the solvent and collisional gas pressures adjusted in order to observe their potential influences. The results obtained provide insight into the

APA, Harvard, Vancouver, ISO, and other styles

13

Vangani, Saroj. "Development of an in vitro dissolution model to predict the in vivo behavior of poorly soluble compounds." Scholarly Commons, 2010. https://scholarlycommons.pacific.edu/uop_etds/2412.

Full text

Abstract:

One of the challenges of biopharmaceutics research is correlating in vitro drug release information with the in vivo drug profiles often known as in vitro-in vivo correlations (IVIVC). These have huge cost savings in pharmaceutical industry. This dissertation describes the development of a novel in vitro dissolution model that has been designed to evaluate the in vitro release of poorly water-soluble model compounds so as to predict their in vivo behavior. The flow through apparatus (USP 4) has been coupled with the compendial dissolution apparatus (USP 2). A bi-phasic dissolution medium has b

APA, Harvard, Vancouver, ISO, and other styles

14

Er-Rhaimini, Abderrahman. "Hétérocycles azotes N-benziles : synthèse de dérivés N-benziles de l'adénine : étude de la photoélimination de substituants benzyliques." Angers, 1986. http://www.theses.fr/1986ANGE0002.

Full text

Abstract:

Synthèse des cinq N-(dimethoxy-3,5 benzyl) adénines. Photolyse de ces compose en solution aqueuse. Tentative de synthèse de l'(imidazo (1,2-a) pyridinyl-6methyl)-1 adénine. Ce travail montre que des substituants benzyliques photoéliminables peuvent être utilisés comme groupes protecteurs dans des synthèses mettant en jeu l'adénine et ses dérivés.

APA, Harvard, Vancouver, ISO, and other styles

15

Wiser, Lauren Sample. "Mechanisms of polymer adsorption in nanoparticle stabilization for poorly water soluble compounds." Scholarly Commons, 2011. https://scholarlycommons.pacific.edu/uop_etds/159.

Full text

Abstract:

In this dissertation, the mechanisms of nanosuspension stabilization via polymer adsorption on nanoparticle surface were investigated. As the electrokinetic behavior and colloidal stability depend on the surface characteristics, altering the surface adsorbed polymers affords the different surface properties of nanoparticles and leads to the insight on the mechanism of nanoparticle stabilization. Drug nanosuspensions were prepared by wet milling of drug with water as medium and polymers as stabilizers. Block copolymers were evaluated based on varying the hydrophobic and hydrophilic amounts, pol

APA, Harvard, Vancouver, ISO, and other styles

16

Rayala, Ramanjaneyulu. "Design and Synthesis of Novel Nucleoside Analogues: Oxidative and Reductive Approaches toward Synthesis of 2'-Fluoro Pyrimidine Nucleosides." FIU Digital Commons, 2015. http://digitalcommons.fiu.edu/etd/2172.

Full text

Abstract:

Fluorinated nucleosides, especially the analogues with fluorine atom(s) in the ribose ring, have been known to exert potent biological activities. The first part of this dissertation was aimed at developing oxidative desulfurization-fluorination and reductive desulfonylation-fluorination methodologies toward the synthesis of 2'-mono and/or 2',2'-difluoro pyrimidine nucleosides from the corresponding 2'-arylthiopyrimidine precursors. Novel oxidative desulfurization-difluorination methodology was developed for the synthesis of α,α-difluorinted esters from the corresponding α-arylthio esters, whe

APA, Harvard, Vancouver, ISO, and other styles

17

Mantheni, Dhruthiman Reddy. "NOVEL SOLIS STATE PROPERTIES OF DRUGS, POLYMERS AND VARIOUS CHEMICALS BY THERMAL AND ANALYTICAL TECHNIQUES." Cleveland State University / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=csu1356019701.

Full text

APA, Harvard, Vancouver, ISO, and other styles

18

Anderson, Michael D. 1980. "Novel Misfit Layer Systems: Synthesis and Characterization." Thesis, University of Oregon, 2011. http://hdl.handle.net/1794/12092.

Full text

Abstract:

xxiv, 265 p. : ill. (some col.)<br>Stabilizing mechanisms and design considerations for generating misfit layer compounds with a variety of different structural motifs were explored using designed precursors consisting of elemental layers. Layer order in the precursor film and the behavior of binary reaction couples was used to avoid undesirable reaction intermediates. Electron diffraction patterns of CuCr2 Se4 were inconsistent with prior reports that this compound has the spinel structure and were more consistent with a hexagonal R 3 ̄ structure. STEM imaging also suggests CuCr2 Se4 prepa

APA, Harvard, Vancouver, ISO, and other styles

19

Ramírez-Vélez, Nicolás. "Parametrization of equations of state : definition of a methodology applicable to SAFT models for pure species (with and without association term) and evaluation of their influence on model performances." Electronic Thesis or Diss., Université de Lorraine, 2022. http://www.theses.fr/2022LORR0020.

Full text

Abstract:

Les modèles thermodynamiques sont au cœur des outils de modélisation en génie des procédés qui fournissent, d’une part, la description, tant qualitative que quantitative des équilibres de phase des mélanges complexes, et d’autres part, une mesure des propriétés énergétiques (enthalpies, entropies, capacités thermiques) nécessaires à l’établissement des bilans énergétique et exergétique. Ce travail s’intéresse en particulier aux équations d’état issues de la théorie statistique des fluides associés (SAFT) appliquées aux corps purs. Notre objectif principal est de proposer des méthodes de paramé

APA, Harvard, Vancouver, ISO, and other styles

20

Nguyen, Hai Trung. "Transfert hydrique dans le milieu poreux réactif : Application à l’étude de séchage d’une pâte pure ettringitique au jeune âge." Thesis, Lyon, 2018. http://www.theses.fr/2018LYSEI124/document.

Full text

Abstract:

Les chapes autonivelantes sont souvent composées de ciment alumineux et de sulfate de calcium pour assurer une prise rapide. Le ciment alumineux est généralement à base de monocalcium aluminate (CA). Récemment, un nouveau ciment alumineux riche en mayénite (C12A7) a été conçu pour optimiser l’application des chapes par l’augmentation de la quantité d’ettringite formée. Le développement de l’hydratation au jeune âge (pendant les premières 24 heures) de ce type de produit est pourtant très peu connu. L’objectif principal de cette étude est d’évaluer l’interaction entre l’hydratation au jeune âge

APA, Harvard, Vancouver, ISO, and other styles

21

Esteban, Christèle. "Etude des procédés utilisables en vue du recyclage de l'eau ultrapure usée dans une usine de micro-électronique." Chambéry, 1999. http://www.theses.fr/1999CHAMS002.

Full text

Abstract:

A Crolles, l'entreprise STMicroelectronics utilise des quantités importantes (68 m#3/h) d'eau de ville pour produire de l'eau dite ultrapure, répondant à des critères de pureté très exigeants. Des raisons économiques et environnementales justifient l'étude du recyclage de cette eau utilisée en rinçage, pour enlever les résidus de produit chimique de la surface des circuits intégrés. Nous avons mis en évidence dans ces eaux la présence d'isopropanol constituant le carbone organique total (COT). L'influence n2gative du COT des eaux de rinçage sur le rendement de fabrication des circuits, nous a

APA, Harvard, Vancouver, ISO, and other styles

22

Santos, Ana Catarina Almeida. "Purine removal with graphene based materials foreseeing their application in the brewing industry." Master's thesis, 2019. http://hdl.handle.net/10773/30111.

Full text

Abstract:

Beer exhibit purine compounds which are catabolized into uric acid leading to its serum level increase which may contribute to hyperuricemia and gout. Thus, it is relevant develop an efficient and selective method to remove these compounds from beer. An iron oxide functionalized graphene-based material was prepared through a sustainable approach, characterized and used to remove purine compounds in an aqueous media. Kinetic and equilibrium isotherm studies were applied to purines and aromatic amino acid adsorption to understand the mechanisms of the process, the relationship with the su

APA, Harvard, Vancouver, ISO, and other styles

23

Nekardová, Michaela. "Výpočetní studie interakcí malých molekul s jejich biologickými cíly." Doctoral thesis, 2020. http://www.nusl.cz/ntk/nusl-411413.

Full text

Abstract:

The thesis specializes in the computational description of pharmaceutically important compounds. A substantial number of pharmaceutical drugs are small molecules that are bound to an active site of an enzyme by the "lock (binding site) and key (drug)" model through non-covalent interactions. The association of enzymes with drugs cause an increase or decrease in the activity of enzymes. The main topic is focused on the computational elucidation of the structural basis for the interactions of the purine-like compounds with the enzyme cyclin- dependent kinase 2 that belongs to the protein-kinase

APA, Harvard, Vancouver, ISO, and other styles

24

Moreira, Filipa Alexandra Lima. "Development of aqueous (micellar) two phase systems to continously purify macroalgae compounds." Master's thesis, 2018. http://hdl.handle.net/10773/25592.

Full text

Abstract:

Currently, macroalgae have been widely studied as a new raw material in the industry. This high interest is due to the fact that macroalgae have attractive production conditions, as well as having high added value compounds, such as phycobiliproteins. Phycobiliproteins, in particular R-phycoerythrin, are proteins that act as natural light-picking pigments, which have very attractive biological properties, especially antioxidant, anticancer and anti-inflammatory properties. Therefore, given the interesting characteristics of this protein, many companies have developed a high interest in these m

APA, Harvard, Vancouver, ISO, and other styles

25

Huang, Chao-Ying, and 黃昭穎. "Effect of Drying Methods on Functional Compounds and Their AntioxidantActivity of Purple Flesh SweetPotato（PFSP）." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/70952045469906468854.

Full text

Abstract:

碩士<br>大葉大學<br>生物產業科技學系<br>97<br>The goal of this study was to investigate the effect of different drying conditions on the functional compounds and antioxidant activities of purple-flesh sweet potato(PFSP). The physical properties and chemical composition of the powder of PFSP were also determined. Fresh PFSPs were peeled, blanched and cut into cubes, then dried by oven or freeze-drying to get the powder for analyses. The pigments of PFSP powder were extracted by the water or ethanol or methanol and its functional compounds and antioxidant activities were determined. The results were shown as

APA, Harvard, Vancouver, ISO, and other styles

26

Polewan, Robert J. "Physiological and behavioral studies of rabbit eyeblink conditioning under temporal uncertainty: Purkinje cell response and compound conditioning." 2006. https://scholarworks.umass.edu/dissertations/AAI3212748.

Full text

Abstract:

The present study employed electrophysiological and behavioral approaches to investigate conditioned response (CR) timing and integration when rabbits were trained with a temporal uncertainty paradigm. The temporal uncertainty paradigm involved training with a mixture of two interstimulus intervals (ISIs) of 300 and 700-ms. Previous work reported that when rabbits were trained using two CS-US, the resulting CRs showed bimodal amplitude peaks (Moore & Choi, 1997). Principle activities investigated in this study included a recordings experiment designed to investigate the expression of CR integr

APA, Harvard, Vancouver, ISO, and other styles

27

Hirawan, Rhanissa. "Antioxidant properties of spaghetti and infant cereals and characterization of major phenolic compounds by LC/MS analysis." 2011. http://hdl.handle.net/1993/4499.

Full text

Abstract:

The present study investigated the antioxidant properties of commercial regular- and whole- wheat spaghetti. The antioxidant properties comprise the total phenolic content, DPPH radical scavenging activity, oxygen radical absorbance capacity. The contents of ferulic acid, C-glycosyl flavones and SDG were measured by using LC/MS techniques. Whole wheat spaghetti showed significantly higher TPC and ORAC. The contents of ferulic acid, C-glycosyl flavones and SDG were significantly higher in whole wheat spaghetti. The TPC was found to decrease 48 – 78% after cooking. The results showed that consum

APA, Harvard, Vancouver, ISO, and other styles

28

Yu, Lilei. "Identification and Antioxidant Properties of Phenolic Compounds during Production of Bread from Purple Wheat Grains and Investigation of Bread Extracts after Simulated Gastrointestinal Digestion." 2014. http://hdl.handle.net/1993/24316.

Full text

Abstract:

Content of free- (FPC) and bound- phenolics (BPC) significantly (p<0.05) increased during mixing, fermenting and baking. Bread crust and crumb contained the highest FPC and BPC, respectively. Antioxidant activities (AOA) followed the trends of their respective phenolic contents. HPLC analysis demonstrated that different phenolic acids showed various responses to the bread-making process. Total anthocyanin content (TAC) was significantly (p<0.05) reduced through mixing and baking, but fermentation elevated the levels. Anthocyanin extract of purple wheat exerted higher AOA than those of common w

APA, Harvard, Vancouver, ISO, and other styles

29

Shahcheraghi, Nikta. "Synthesis of novel plasmonic materials and their optical properties." Thesis, 2016. http://hdl.handle.net/10453/90040.

Full text

Abstract:

University of Technology Sydney. Faculty of Science.<br>The field of ‘plasmonics’ has gained a lot of attention recently. This is because plasmonic phenomena can be used in a wide variety of modern devices, including biosensors, intracellular probes, spectrally-selective coatings, hyperthermal medical treatments, new kinds of photonic devices, nano-optics, scanning microscopy and optical cloaking. One issue with plasmonics, however, is that the metallic materials currently used cause high losses due to conversion of light to heat. The aim of my project was to discover ways to minimize optical

APA, Harvard, Vancouver, ISO, and other styles

30

El-Khatib, Mayar. "Highway Development Decision-Making Under Uncertainty: Analysis, Critique and Advancement." Thesis, 2010. http://hdl.handle.net/10012/5741.

Full text

Abstract:

While decision-making under uncertainty is a major universal problem, its implications in the field of transportation systems are especially enormous; where the benefits of right decisions are tremendous, the consequences of wrong ones are potentially disastrous. In the realm of highway systems, decisions related to the highway configuration (number of lanes, right of way, etc.) need to incorporate both the traffic demand and land price uncertainties. In the literature, these uncertainties have generally been modeled using the Geometric Brownian Motion (GBM) process, which has been used extens

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!