Relevant bibliographies by topics / Purine derivatives

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Purine derivatives'

Author: Grafiati
Published: 4 June 2021
Last updated: 26 July 2025

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Journal articles on the topic "Purine derivatives"

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Verbic, J., X. B. Chen, N. A. MacLeod, and E. R. Ørskov. "Excretion of purine derivatives by ruminants. Effect of microbial nucleic acid infusion on purine derivative excretion by steers." Journal of Agricultural Science 114, no. 3 (1990): 243–48. http://dx.doi.org/10.1017/s0021859600072610.

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SUMMARYTwo steers totally nourished by intragastric infusion of volatile fatty acids and casein were given an abomasal infusion of a microbial protein preparation (Pruteen) at eight rates with a purine input ranging from 0 to 170 mmol/day over 11 successive 5-day periods. The urinary excretion of purine derivatives relative to the purine input was measured. Negligible amounts of xanthine plus hypoxanthine were present in the urine. The relative contributions of allantoin and uric acid to the total excretion were not affected by the rate of purine infusion. Total purine derivative excretion (ur
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Giráldez, F. J., R. Peláez, E. Zorita, and C. Valdés. "Purine derivatives excretion in sheep urine in relation to metabolizable energy and rumen degradable protein intake." Proceedings of the British Society of Animal Production (1972) 1993 (March 1993): 186. http://dx.doi.org/10.1017/s0308229600025083.

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Recently has been shown that allantoin or total purine derivatives excretion in urine are strongly related to the amount of purines reaching the small intestine (Chen et al., 1990; Balcells et al., 1992) and as consequence purine derivative output is propouse to be used as an index of microbial protein flow to small intestine.Because energy and rumen degradable protein supplies are the main factors affecting rumen microbial growth, the effect of changes in rumen degradable protein supplies at different levels of ME intake on urinary excretion of purine derivatives was studied in this work.
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Chen, X. B., F. D. DeB Hovell, E. R. Ørskov, and D. S. Brown. "Excretion of purine derivatives by ruminants: effect of exogenous nucleic acid supply on purine derivative excretion by sheep." British Journal of Nutrition 63, no. 1 (1990): 131–42. http://dx.doi.org/10.1079/bjn19900098.

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The present study examined the relationship between the supply of exogenous nucleic acid (NA) purines and their recovery as the derivatives hypoxanthine, xanthine, uric acid and allantoin in urine. Six lambs, totally nourished by intragastric infusions of volatile fatty acids (VFA) and casein (i.e. no rumen fermentation), were given by abomasal infusion a microbial NA concentrate at six levels (from zero to 24·5 mmol purines/d). The true digestibility between the abomasum and terminal ileum of the NA purines was measured in a separate experiment using three lambs. The relative proportion of ur
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Surra, J., J. A. Guada, J. Balcells, and C. Castrillo. "Salivary losses of purine derivatives in sheep." Proceedings of the British Society of Animal Production (1972) 1993 (March 1993): 176. http://dx.doi.org/10.1017/s0308229600024983.

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Developed models to estimate rumen microbial yield from the urinary excretion of purine derivatives fail to account for a complete absorbed purines (Chen et al., 1990a, Balcells et al., 1991). Ruminal degradation of purine derivatives recycled via saliva has been suggested as a possible explanation after detecting the presence of allantoin and uric acid in the sheep saliva (Chen et al. 1990b). However, it is not known to what extent these losses may be affected by dietary induced variations in saliva flow (Kay, 1966).This paper reports preliminary results of an experiment designed to study the
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Šála, Michal, Hubert Hřebabecký, Milena Masojídková, and Antonín Holý. "Synthesis of Novel Racemic Conformationally Locked Carbocyclic Nucleosides Derived from 7-Substituted Bicyclo[2.2.1]hept-5-ene-2,2-dimethanols." Collection of Czechoslovak Chemical Communications 71, no. 5 (2006): 635–49. http://dx.doi.org/10.1135/cccc20060635.

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(1R*,4R*,7S*)-7-Aminobicyclo[2.2.1]hept-5-ene-2,2-dimethanol (15) was prepared in four easy steps from bicyclo[2.2.1]hept-5-ene-2,2-dimethanol (10). Reaction of amine 15 with ethyl N-((E)-3-ethoxymethacryloyl)carbamate afforded thymine derivatives 17a. The amine 15 was used to construct 6-chloro-9H-purine derivative 19a, 2-amino-6-chloro-9H-purine derivative 22a. Ammonolysis of 19a led to the adenine derivative 20a. Treatment of 22a with trifluoroacetic acid afforded guanine nucleoside 23a. (1R*,4R*,7S*)-7-[6-(Cyclopropylamino)-9H-purin-9-yl]bicyclo[2.2.1]hept-5-ene-2,2-dimethanol (21a) and (1
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Balcells, J., J. A. Guada, C. Castrillo, and J. Gasa. "Urinary excretion of allantoin and allantoin precursors by sheep after different rates of purine infusion into the duodenum." Journal of Agricultural Science 116, no. 2 (1991): 309–17. http://dx.doi.org/10.1017/s002185960007773x.

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SUMMARYTwo experiments were carried out to determine endogenous losses and the response of urinary purine derivatives to increased duodenal inputs of purine bases. Four ewes each fitted with a re-entrant cannula at the proximal duodenum, and conventionally fed, were subjected to full replacement of duodenal digesta followed by the administration of a solution either free of purines (Expt 1) or enriched with increasing amounts of purines, to supply 0·48–21·27 mmol/animal per day (Expt 2). Basal daily urinary excretions of allantoin, uric acid, hypoxanthine and xanthine were 11·5 ± 0·94, 9·9 ± 0
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Muzychka, Oksana, Olexandr Kobzar, Oleg Shablykin, Volodymyr Brovarets, and Andriy Vovk. "5-Substituted N-(9H-purin-6-yl)-1,2-oxazole-3-carboxamides as xanthine oxidase inhibitors." Ukr. Bioorg. Acta 2020, Vol. 15, N1 15, no. 1 (2020): 20–25. http://dx.doi.org/10.15407/bioorganica2020.01.020.

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Synthetic 6-substituted purine derivatives are known to exhibit diverse bioactivity. In this paper, a series of N-(9H-purin-6-yl)-1,2-oxazole-3-carboxamide derivatives were synthesized and evaluated in vitro against xanthine oxidase, an enzyme of purine catabolism. The introduction of aryl substituent at position 5 of the oxazole ring was found to increase the inhibition efficiency. Some of the inhibitors containing 5-substituted isoxazole and purine moieties were characterized by IC50 values in the nanomolar range. According to the kinetic data, the most active N-(9H-purin-6-yl)-5-(5,6,7,8-te
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Matsumura, Nobuko, and Koji Aoyama. "Glutathione-Mediated Neuroprotective Effect of Purine Derivatives." International Journal of Molecular Sciences 24, no. 17 (2023): 13067. http://dx.doi.org/10.3390/ijms241713067.

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Numerous basic studies have reported on the neuroprotective properties of several purine derivatives such as caffeine and uric acid (UA). Epidemiological studies have also shown the inverse association of appropriate caffeine intake or serum urate levels with neurodegenerative diseases such as Alzheimer disease (AD) and Parkinson’s disease (PD). The well-established neuroprotective mechanisms of caffeine and UA involve adenosine A2A receptor antagonism and antioxidant activity, respectively. Our recent study found that another purine derivative, paraxanthine, has neuroprotective effects simila
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Krečmerová, Marcela, Milena Masojídková, and Antonín Holý. "Synthesis of N9- and N7-[2-Hydroxy-3-(phosphonomethoxy)propyl] Derivatives of N6-Substituted Adenines, 2,6-Diaminopurines and Related Compounds." Collection of Czechoslovak Chemical Communications 69, no. 10 (2004): 1889–913. http://dx.doi.org/10.1135/cccc20041889.

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Base-catalyzed reactions of diethyl [(oxiranylmethoxy)methyl]phosphonate (2) with purine bases (adenine, 2,6-diaminopurine, 6-chloropurine and 2-amino-6-chloropurine) gave corresponding 9- or 7-[2-hydroxy-3-(phosphonomethoxy)propyl] purines. The adenine and 2,6-diaminopurine derivatives cyclize to cyclic phosphonates 4 and 6. The 9-[2-hydroxy-3-(phosphonomethoxy)propyl] derivatives of N6-substituted adenine and 2,6-diaminopurine (15-27) were prepared by the treatment of diethyl {[3-(6-chloropurin-9-yl)-2-hydroxypropoxy]methyl}phosphonate (11) or diethyl {[3-(2-amino-6-chloropurin-9-yl)-2-hydro
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Safranow, Krzysztof, and Zygmunt Machoy. "Methylated Purines in Urinary Stones." Clinical Chemistry 51, no. 8 (2005): 1493–98. http://dx.doi.org/10.1373/clinchem.2005.048033.

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Abstract Background: The aim of the study was to measure the content of methylated purines that appear as admixtures in uric acid stones. Methods: We analyzed urinary calculi from 48 residents of Western Pomerania who underwent surgery at the urology ward in Szczecin. Stone samples were dissolved in 0.1 mol/L NaOH. Extracts were diluted in 50 mmol/L KH2PO4 and analyzed by reversed-phase HPLC with ultraviolet detection and use of a gradient of methanol concentration and pH. Results: Uric acid was the main component of 9 stones. All 9 showed admixtures of 9 other purine derivatives: endogenous p
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Dissertations / Theses on the topic "Purine derivatives"

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Shubietah, Raqi Moh'd Hasan. "Adsorptive stripping voltammetry as a method of analysis of some pharmaceutical and other purine derivatives." Thesis, Loughborough University, 1995. https://dspace.lboro.ac.uk/2134/11215.

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Adsorptive stripping voltammetry (AdSV) is a recent technique (initially named by Lam, Kalvoda and Kopanica in 1983) in which there is generally a nonelectrolytic accumulation (adsorption) of the determinand followed by a cathodic reductive or anodic oxidative scan. In this work, a hanging mercury drop electrode (HMDE) was used to accumulate several purine derivatives with and without the addition of Cu(lI) in a suitable buffer (usually Britton-Robinson, pH 7.5). In the presence of copper(lI) the copper(l) purine complex was usually accumulated at about -0.1 V. Some of the compounds studied (i
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Chen, Xue Bin. "Excretion of purine derivatives by sheep and cattle and its use for the estimation of absorbed microbial protein." Thesis, University of Aberdeen, 1989. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=128449.

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The nucleic acids digested by ruminants are essentially of microbial origin. Absorbed purines are extensively degraded and excreted in urine as allantoin, uric acid, xanthine and hypoxanthine. The measurement of the urinary purine derivatives could be used to estimate the uptake of purines and hence that of microbial protein. 1) Automated methods for measurements of purine derivatives were improved. A HPLC method for determining total adenine and guanine was used to measure the purine contents of mixed rumen bacteria and the digestibility of microbial purines in sheep. 2) Endogenous excretions
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Gilliam, Sarah Elizabeth. "The mode of action and therapeutic potential of purine and pyrimidine phosphonylmethoxyalkyl derivatives against bovine herpesvirus-1." Thesis, University of Cambridge, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.319534.

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Dhanda, Anupma. "Novel carbocyclic purine derivatives at TNF- #alpha# inhibitors and novel polyamino acids for asymmetric epoxidation of enones." Thesis, University of Liverpool, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.367101.

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Ahnert, Veronika Sandra [Verfasser]. "Response of urinary purine derivatives excretion to nutritional factors affecting ruminal microbial protein synthesis in cattle / Veronika Sandra Ahnert." Kiel : Universitätsbibliothek Kiel, 2015. http://d-nb.info/1072621436/34.

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Oliveira, Lisandre de. "Métodos em nutrição de ruminantes: uso de índices fecais para estimar consumo e estimativa da síntese proteica microbiana ruminal." Universidade Federal de Santa Maria, 2009. http://repositorio.ufsm.br/handle/1/10733.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico<br>This study was carried out to evaluate methods in ruminant nutrition: use of fecal index to estimate intake and use of purine or purine derivatives to estimate rumen microbial protein synthesis. Data from three digestibility trials conducted with castrated male lambs fed ryegrass (Lolium multiflorum, Lam) or Cynodon (Cynodon dactylon var dactylon) at different levels of intake were compiled. Intake data were related to faecal excretion of different chemical compounds through regression analysis. Significant regressions with high
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Tyagi, Surendera Kumar. "Electrochemical and enzyme-catalyzed oxidation chemistry of some biologically important purine derivatives (uric acid, 9-B-D-ribofuranosyluric acid and xanthosine) /." Full-text version available from OU Domain via ProQuest Digital Dissertations, 1986.

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Silva, Júnior Jarbas Miguel da. "Excreção urinária de derivados de purinas e de compostos nitrogenados de zebuínos em pastejo." Universidade Federal de Viçosa, 2014. http://locus.ufv.br/handle/123456789/5825.

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Made available in DSpace on 2015-03-26T13:55:26Z (GMT). No. of bitstreams: 1 texto completo.pdf: 876963 bytes, checksum: 2254ce6044753867875b6bfab3b2249e (MD5) Previous issue date: 2014-07-21<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>This study aimed evaluating the excretion of purine derivatives and nitrogen compounds in zebu cattle grazing, on different days and times within days. The experiment was conducted in the cattle department of the Federal University of Viçosa / MG, using five Nelore heifers with an average body weight of 300 ± 15 kg and 20 months of age, i
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Stefanello, Cristiano Miguel. "Avaliação de marcadores internos para estimativa de fluxo de digesta e proteína microbiana no duodeno de ruminantes." Universidade Federal de Santa Maria, 2014. http://repositorio.ufsm.br/handle/1/10849.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>The aim of this study was to evaluate the use of internal markers to estimate duodenal flow of digesta and duodenal microbial protein synthesis in cattle and sheep. Data and samples of in vivo digestibility trials, eight trials with sheep (n=204) and two with cattle (n=31) were used. All animals were cannulated in the duodenum, procedure previously conducted at the Laboratory of Food Science and Ruminants Nutrition at the Federal University of Santa Maria and Laboratory of Animal Nutrition and Food Science at the University of the
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Zanferari, Filipe. "Quitosana associada a grão de soja integral na alimentação de vacas leiteiras: I. Digestão, metabolismo e desempenho produtivo; II. Avaliação de metodologias para estimativas da digestibilidade aparente total e produção microbiana ruminal." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/10/10135/tde-22062017-143018/.

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A presente tese foi elaborada em três capítulos, correspondente às seções 2, 3 e 4. No primeiro objetivou-se avaliar a associação de quitosana com grão de soja integral nas dietas sobre o consumo, fermentação ruminal, digestibilidade e metabolismo de nutrientes e seus efeitos sobre a produção de leite, perfil de ácidos graxos do leite e a eficiência produtiva de vacas em lactação. Para tal, 24 vacas multíparas da raça Holandesa, oito dessas com cânula ruminal, foram distribuídas em quadrados latinos 4×4 replicados. Os tratamentos foram obtidos por esquema fatorial 2×2 pela combinação de quitos
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Books on the topic "Purine derivatives"

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Makkar, Harinder P. S., and X. B. Chen, eds. Estimation of Microbial Protein Supply in Ruminants Using Urinary Purine Derivatives. Springer Netherlands, 2004. http://dx.doi.org/10.1007/978-1-4020-2844-1.

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1951-, Lusty James R., Wearden Peter, and Moreno Virtudes, eds. CRC handbook of nucleobase complexes: Transition metal complexes of naturally occuring nucleobases and their derivatives. CRC Press, 1990.

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Chen, X. B., and Harinder P. S. Makkar. Estimation of Microbial Protein Supply in Ruminants Using Urinary Purine Derivatives. Springer London, Limited, 2004.

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Makkar, Harinder P. S. Estimation of Microbial Protein Supply in Ruminants Using Urinary Purine Derivatives. Springer, 2013.

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Harinder P.S. Makkar (Editor) and X. B. Chen (Editor), eds. Estimation of microbial protein supply in ruminants using urinary purine derivatives. Springer, 2006.

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Shubietah, Raqi Mohammad Hasan. Adsorptive stripping voltammetry as a method of analysis of some pharmaceutical and other purine derivatives. 1995.

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Chen, Xue Bin. Excretion of purine derivatives by sheep and cattle and its use for the estimation of absorbed microbial protein. 1989.

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(Editor), H. U. Bergmeyer, J. Bermeyer (Editor), and M. Bral (Editor), eds. Methods of Enzymatic Analysis, 3.eE, Vol. 7, Metabolites 2: Tri- and Dicarboxylic Acids, Purines, Pyrimidines and Derivatives, Coenzymes, Inorganic Compounds. 3rd ed. John Wiley & Sons, 1985.

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Lusty, James R., and Peter Wearden. Handbook of Nucleobase Complexes: Transition Metal Complexes of the Naturally Occurring Nucleobases and Their Derivative. CRC Press, 1991.

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Nishizawa, Taiji. Thermodynamics of Microstructures. ASM International, 2008. http://dx.doi.org/10.31399/asm.tb.tm.9781627083577.

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Thermodynamics of Microstructures provides a mathematical treatment of the microstructure of materials and the processes and mechanisms involved in its formation. The first few chapters cover the basics of thermodynamics and its application to pure substances, solutions, mixtures, and compounds. Subsequent chapters apply the principles of thermodynamics to phase diagrams and multicomponent systems, interfaces and grain boundaries, diffusion processes, ordering, nucleation, and microstructure changes. The information in the book is presented in a Q&amp;A style and each chapter includes exercise
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Book chapters on the topic "Purine derivatives"

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Schoettle, Sarah L., and Richard I. Christopherson. "Inhibition of Murine Amido Phosphoribosyltransferase by Folate Derivatives." In Purine and Pyrimidine Metabolism in Man VIII. Springer US, 1995. http://dx.doi.org/10.1007/978-1-4615-2584-4_34.

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Piani, B., C. Fabro, and P. Susmel. "Measurement of Purine Derivatives and Creatinine in Urine by HPLC." In Estimation of Microbial Protein Supply in Ruminants Using Urinary Purine Derivatives. Springer Netherlands, 2004. http://dx.doi.org/10.1007/978-1-4020-2844-1_18.

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Bronson, Joanne J., Choung Un Kim, Ismail Ghazzouli, Michael J. M. Hitchcock, Earl R. Kern, and John C. Martin. "Synthesis and Antiviral Activity of Phosphonylmethoxyethyl Derivatives of Purine and Pyrimidine Bases." In ACS Symposium Series. American Chemical Society, 1989. http://dx.doi.org/10.1021/bk-1989-0401.ch005.

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Balcells, J., F. Vicente, P. Orellana-Boero, S. Martin-Orue, and M. Gonzalez-Ronquillo. "Effect of Physiological Status on Endogenous Excretion of Purine Derivatives in Cattle." In Estimation of Microbial Protein Supply in Ruminants Using Urinary Purine Derivatives. Springer Netherlands, 2004. http://dx.doi.org/10.1007/978-1-4020-2844-1_4.

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Chen, X. B., and E. R. Ørskov. "Research on Urinary Excretion of Purine Derivatives in Ruminants: Past, Present and Future." In Estimation of Microbial Protein Supply in Ruminants Using Urinary Purine Derivatives. Springer Netherlands, 2004. http://dx.doi.org/10.1007/978-1-4020-2844-1_21.

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Chen, X. B., M. C. N. Jayasuriya, and H. P. S. Makkar. "Measurement and Application of Purine Derivatives:Creatinine Ratio in Spot Urine Samples of Ruminants." In Estimation of Microbial Protein Supply in Ruminants Using Urinary Purine Derivatives. Springer Netherlands, 2004. http://dx.doi.org/10.1007/978-1-4020-2844-1_20.

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Nimmo-Smith, R. H. "The Function of Folic Acid in the Biosynthesis of Purine and Pyrimidine Derivatives." In Ciba Foundation Symposium - Chemistry and Biology of Pteridines. John Wiley & Sons, Ltd., 2008. http://dx.doi.org/10.1002/9780470718919.ch19.

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Xing, Z., W. B. Xi, F. Mo, J. W. Liu, Y. F. Yang, and X. B. Chen. "Measurements of Purine Derivatives and Creatinine in Spot Urine Samples of Chinese Yellow Cattle." In Estimation of Microbial Protein Supply in Ruminants Using Urinary Purine Derivatives. Springer Netherlands, 2004. http://dx.doi.org/10.1007/978-1-4020-2844-1_13.

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Orellana, R., P. Pulido, M. Briones, and A. Sarabia. "Purine Derivatives/Creatinine Ratio as an Index of Microbial Protein Synthesis in Lactating Holstein Cows." In Estimation of Microbial Protein Supply in Ruminants Using Urinary Purine Derivatives. Springer Netherlands, 2004. http://dx.doi.org/10.1007/978-1-4020-2844-1_15.

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Poshiwa, X., N. T. Ngongoni, B. Manyuchi, C. Chakoma, and A. Tigere. "The Effect of Plane of Nutrition on the Urinary Purine Derivative Excretion in Sheep and Goats." In Estimation of Microbial Protein Supply in Ruminants Using Urinary Purine Derivatives. Springer Netherlands, 2004. http://dx.doi.org/10.1007/978-1-4020-2844-1_17.

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Conference papers on the topic "Purine derivatives"

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Trabanelli, G., A. Frignani, G. Brunoro, C. Monticelli, and F. Zucchi. "Corrosion and Inhibition of Low Alloyed Chromium Steels in Hydrofluoric Acid Solutions." In CORROSION 1985. NACE International, 1985. https://doi.org/10.5006/c1985-85376.

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Abstract This paper investigates the influence chromium content exerts on the corrosion resistance of low alloyed chromium steels in hydrofluoric acid solution and compares it with the corrosion resistance in other acids, such as hydrochloric, perchloric and sulphuric. Weight losses were performed on ASTM A 106 steel and on ASTM A335 type steel (chromium content: 1.5-10%) in 1.7 N HF; 1.4 N HCl; 1.5 N H2SO4 and 1.5 N HClO4 at 45 °C. These tests showed that chromium decreases the corrosion resistance of the tested iron-chromium alloys in HClO4, H2SO4 and especially in HF solutions. Different pu
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Borisut, Prapatsorn, Bianca Williams, Aroonsri Nuchitprasittichai, and Selen Cremaschi. "Design and Optimization of Methanol Production using PyBOUND." In Foundations of Computer-Aided Process Design. PSE Press, 2024. http://dx.doi.org/10.69997/sct.194568.

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In this paper, we study the design optimization of methanol production with the goal of minimizing methanol production cost. One challenge of methanol production via carbon dioxide (CO2) hydrogenation is the reduction of operating costs. The simulation of methanol production is implemented within the Aspen HYSYS simulator. The feeds are pure hydrogen and captured CO2. The process simulation involves a single reactor and incorporates recycling at a ratio of 0.995. The methanol production cost is determined using an economic analysis. The cost includes capital and operating costs, which are dete
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Mahanani, Mutiara Mustika Putri, Chusnul Hanim, and Lies Mira Yusiati. "Excretion of Endogenous Purine Derivatives in Male and Female Garut sheep." In 9th International Seminar on Tropical Animal Production (ISTAP 2021). Atlantis Press, 2022. http://dx.doi.org/10.2991/absr.k.220207.010.

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Guven, Ebru Bilget, Meral Tuncbilek, Tulin Ersahin, Zerrin Demir, Mehmet Ozturk, and Rengul Cetin Atalay. "Abstract A171: Cytotoxicity of novel substituted purine derivatives against liver cancer cells." In Abstracts: AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics--Nov 15-19, 2009; Boston, MA. American Association for Cancer Research, 2009. http://dx.doi.org/10.1158/1535-7163.targ-09-a171.

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"Characterization of Purine Based Biosensor for Electrochemical Determination of Benzene and its Derivatives." In 2nd International Conference on Research in Science, Engineering and Technology. International Institute of Engineers, 2014. http://dx.doi.org/10.15242/iie.e0314567.

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Novosjolova, Irina, Ērika Bizdēna, and Māris Turks. "Derivatives of 2,6-diazidopurine and 2,6-bis-(1,2,3-triazol-1-yl) purine as useful intermediates in the synthesis of modified purine nucleosides." In XVIth Symposium on Chemistry of Nucleic Acid Components. Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 2014. http://dx.doi.org/10.1135/css201414332.

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Česnek, Michal, Michal Hocek, and Antonín Holý. "Cross-coupling reactions of 2-amino-6-halopurine derivatives with organometallic reagents leading to 6-alkylated purine acyclic nucleotide analogues." In XIth Symposium on Chemistry of Nucleic Acid Components. Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 1999. http://dx.doi.org/10.1135/css199902255.

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Krečmerová, Marcela, Antonín Holý, Dana Hocková, Martin Dračínský, Dianne T. Keough, and Luke W. Guddat. "9-[2-Hydroxy-3-(phosphonomethoxy)propyl] ("iso-HPMP") derivatives of purine bases and their side-chain modified analogues: synthesis and antimalarial activity." In XVth Symposium on Chemistry of Nucleic Acid Components. Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 2011. http://dx.doi.org/10.1135/css201112381.

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Mahanani, Mutiara Mustika Putri, Chusnul Hanim, Kustantinah Kustantinah, Zaenal Bachruddin, Budi Prasetyo Widyobroto, and Lies Mira Yusiati. "Estimation of Rumen Microbial Nitrogen Supply Based on Purine Derivatives Excreted in The Urine of Male and Female Garut Sheep Fed Ad Libitum." In 6th International Seminar of Animal Nutrition and Feed Science (ISANFS 2021). Atlantis Press, 2022. http://dx.doi.org/10.2991/absr.k.220401.021.

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Rojas, Alvaro J., Marcos Esterman, Jeanne M. Wesline, Matthew R. McLaughlin, and Carol-Lynn Goldstein. "A Selection Framework for Derivative Products." In ASME 2007 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2007. http://dx.doi.org/10.1115/detc2007-35859.

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Abstract:
Firms today increasingly seek to leverage product platforms via derivative product versions of the base platform, but successfully doing so is a significant challenge. Numerous enablers are required, such as robust product development processes, effective and well trained organizations, R&amp;D activities that are aligned to support product strategies, and a clearly defined corporate strategy. In derivative product development firms struggle to identify the optimum derivatives to develop and bring to market. Evaluating which feature to improve upon, which technologies to incorporate, which mar
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