Academic literature on the topic 'PVP K-30'

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Journal articles on the topic "PVP K-30"

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Dharmendra, Kumar. "Domperidone Nasal Gel Using Fenugreek Seed as Mucoadhesive Agent: Water Solubility Problem Sort-Out." Trends in Pharmaceuticals and Nanotechnology 2, no. 1 (2019): 1–11. https://doi.org/10.5281/zenodo.3477840.

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<strong><em>Objective</em></strong><em>: </em><em>The aim of this research work was to develop a mucoadhesive nasal gel of domperidone in an aqueous medium. Mixed solvency concept was used to enhance the aqueous solubility of Domperidone. <strong>Methods</strong>: The study was facilitated by collecting fenugreek seeds and subjected to hydro extraction. Mixed solvency concept was used to improve aqueous solubility of domperidone.<strong> Results</strong>: Mucoadhesive agent was extracted from fenugreek seeds by simple hydro extraction. Solubility of domperidone was enhanced by using sodium cit
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Kumala Sari, Lusia Oktora Ruma, Kuni Zu’aimah Barikah, and Via Rahmatia. "OPTIMASI CROSPOVIDONE DAN POLYVINYL PYRROLIDONE K-30 DALAM FORMULASI ORALLY DISINTEGRATING TABLET (ODT) SALBUTAMOL SULFAT." Jurnal Kesehatan Islam : Islamic Health Journal 12, no. 1 (2023): 25–32. http://dx.doi.org/10.33474/jki.v12i1.19900.

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Abstract. The objective of the present study was to optimize crospovidone as a superdisintegrant and polyvinyl pyrrolidone (PVP) K-30 as a binder in ODT salbutamol sulphate. ODT salbutamol sulphate was made by direct compression technique. Optimization was carried out by the factorial design method using Design Expert 11.0 software with optimized responses, including hardness, friability, and disintegration time. The result showed that crospovidone affected the decrease in the disintegration time of ODT. PVP K-30 affected decreasing friability and increasing hardness and disintegration time of
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Fatmawati, Dina Ayu, Bambang Widjaja, and Dwi Setyawan. "Optimasi Tablet Levofloksasin yang Mengandung Bahan Pengikat PVP K-30 dan Disintegran Vivasol." Jurnal Sains Farmasi & Klinis 4, no. 1 (2017): 9. http://dx.doi.org/10.29208/jsfk.2017.4.1.155.

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Penelitian ini bertujuan mendapatkan formula yang optimal tablet levofloksasin yang dibuat dengan variasi PVP K-30 sebagai pengikat dan vivasol sebagai disintegran. Metode pembuatan tablet levofloksasin dilakukan secara granulasi basah. Formula tablet dibuat dengan variasi PVP K-30 dan disintegran vivasol, dikempa menggunakan alat hidrolik press dengan puch diameter 12 mm, selama 3 detik. Evaluasi mutu fisik (kekerasan, kerapuhan, dan waktu hancur) dan laju disolusi tablet. Optimasi formula dilakukan dengan desain faktorial 22 yaitu eksperimen faktorial dengan 2 faktor (PVP K-30 dan vivasol) d
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Lusiana, Retno Ariadi, Riska Nurfida Annisa, Vinsencius Guntur Pandu Marcellino, Didik Setiyo Widodo, and Hasan Muhtar. "Fabrication and Characterization of Chitosan-Polyvinyl Pyrolidone K-30 for Creatinine Transport Membranes." Jurnal Kimia Sains dan Aplikasi 26, no. 10 (2023): 381–90. http://dx.doi.org/10.14710/jksa.26.10.381-390.

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The investigation of membrane-based hemodialysis is an interesting study due to its efficacy in eliminating metabolic waste compounds, such as creatinine, from the body. However, not all membrane types exhibit optimal transport capabilities, necessitating modifications. In this study, we conducted modifications on chitosan (CS) membranes by incorporating polyvinyl pyrrolidone K-30 (PVP K-30) and assessing their physicochemical characteristics. The modified membrane underwent characterization and subsequent evaluation of its transport capabilities. The primary objective of this research is to d
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Sadiarti, Asri Prahmanita, Endang Diyah Ikasari, and A. Ariani Hesti W.S. "PENINGKATAN DISOLUSI NIFEDIPIN DENGAN PELARUT PVP K-30 MENGGUNAKAN METODE DISPERSI PADAT." Jurnal Ilmu Farmasi dan Farmasi Klinik 19, no. 1 (2022): 24. http://dx.doi.org/10.31942/jiffk.v19i1.6680.

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ABSTRACTNifedipine is an anti-hypertensive included in the Biopharmaceutics Classification System (BCS) class II to its nature of being poorly soluble in water, resulting in low bioavailability. One technique that can be used to improve the solubility of the dispersion technique. This research aimed to determine the effect of the concentration of PVP K-30 on physical characteristics, the dissolution rate of solid dispersions, and the interactions that occur between nifedipine with PVP K-30. The method of manufacturing solid dispersion is a melting-solvent method. FI - F III is a solid dispersi
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Sudhir, M., M. Manjusha, R. R. Manjula, N. Jyothi, and N. Lakshmi Prasanthi. "PREPARATION AND EVALUATION OF IBUPROFEN LIQUID FILL FORMULATIONS FOR SOFT GELS." INDIAN DRUGS 54, no. 12 (2017): 65–68. http://dx.doi.org/10.53879/id.54.12.10873.

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The present investigation was undertaken with an objective to prepare and evaluate liquid fill formulations of non-steroidal anti-inflammatory drug, ibuprofen (IBU), in order to improve its dissolution properties and thereby its bioavailability. Liquid fill formulations were prepared by employing different co-solvents and surfactants like polyethylene glycol 400 (PEG 400), propylene glycol (PG) and polyvinylpyrrolidone (PVP K-30). The liquid fills were characterized by assay, rheology, clarity, in vitro dissolution studies and FTIR. More than 90% of the drug was released within 5 min from PVP
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Bhumi, Patel* Dr. Chainesh Shah. "FABRICATION AND IN-VITRO CHARACTERIZATION OF TRANSDERMAL MATRIX PATCH OF KETOPROFEN FOR TRANSDERMAL THERAPEUTIC SYSTEM." Indo American Journal of Pharmaceutical Sciences (IAJPS) 03, no. 09 (2016): 960–73. https://doi.org/10.5281/zenodo.153859.

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Objective: The objective of research work was to improve the permeability of Ketoprofen and to provide controlled release of drug to provide maximum effective concentration. Experimental work: Transdermal drug delivery systems are polymeric patches containing dissolved or dispersed drugs that deliver therapeutic agents at a constant rate to the human skin. Matrix type transdermal patches containing Ketoprofen were prepared by solvent casting method employing aluminium foil method. Polyethylene glycol (PEG) 400 was used as plasticizer and Dimethyl sulfoxide (DMSO) was used as penetration enhanc
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Nair, Bindu. "Final Report On the Safety Assessment of Polyvinylpyrrolidone (PVP)." International Journal of Toxicology 17, no. 4_suppl (1998): 95–130. http://dx.doi.org/10.1177/109158189801700408.

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Polyvinylpyrrolidone (PVP) is a linear polymer of 1-vinyl-2-pyrrolidone monomers used as a binder, emulsion stabilizer, film former, hair fixative, and suspending agent-nonsurfactant. The molecular weight of the polymer ranges from 10,000 to 700,000. PVP K-30, with an average molecular weight of 40,000, is typically used in cosmetic formulations. The highest concentration reported to be used is 35%. There was no significant absorption of PVP K-30 given orally to rats, and the acute oral LD50 was &gt;100 g/kg for rats and guinea pigs. Neither toxic effects nor gross lesions were found in rats m
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Gayo, Zahara, Henny Lucida, and Erizal Zaini. "Solid dispersion of quercetin-PVP K-30 and its effects on the antioxidant activity." Jurnal Ilmiah Farmasi 16, no. 2 (2020): 144–54. http://dx.doi.org/10.20885/jif.vol16.iss2.art6.

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Background: Quercetin (3,3’,4’,5,7-pentahydroxil-flavon) is a flavone and secondary metabolite known as flavonoid. Quercetin belongs to class II BCS that has low solubility and high permeability. The poor solubility of quercetin restricts the accessibility and bioavailability. Objectives: To increase the solubility, dissolution, and antioxidant activity in a solid dispersion system. Methods: Preparation of quersetin-PVP K-30 solid dispersion was conducted using the freeze-drying method at -96 degree C for 24 hours with a ratio of 1:1, 1:0.5, and 0.5:1 and a 1:1 physical mixture of quercetin-PV
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Maulana, Riza, Henry Harto, and Tiara Dewi Salindri Pratama. "Formulation of Nifedipine–Polyvinyl Pyrrolidone (PVP) Solid Dispersion System and Intrinsic Dissolution Rate Evaluation." Pharmacon: Jurnal Farmasi Indonesia 19, no. 2 (2022): 108–14. http://dx.doi.org/10.23917/pharmacon.v19i2.20545.

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Nifedipine is a drug that acts as an antihypertensive and anti-angina. Nifedipine is known as a drug with poor water solubility. This characteristic will affect the intrinsic dissolution rate so that it can affect the absorption process and reduce the amount of drug that reaches systemic circulation. One of the strategies to increase the intrinsic dissolution rate is developing nifedipine to solid dispersions form. This study aims to observe the intrinsic dissolution rate of nifedipine after it has been made into a solid dispersion. Four samples were prepared, including three solid dispersions
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Books on the topic "PVP K-30"

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Morgan, Ruby. Adult Coloring Book of 30 Funny Quotes for K-Pop Lovers: 30 Funny Sayings and Beautiful Mandala Patterns to Color, Art Therapy Activity Book for Anxiety and Stress Relief, Mindful Meditation and Relaxation. Independently Published, 2020.

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Book chapters on the topic "PVP K-30"

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Aishwarya, KVNR, and Praveen Sivadasu. "Preparation of Rilpivirine Nanosponges Using Different Methodologies." In Current Trends in Drug Discovery, Development and Delivery (CTD4-2022). Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/9781837671090-00611.

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Rilpivirine is an analogue of a nucleoside that inhibits reverse transcriptase. Various polymers including ethyl cellulose (EC), -cyclodextrin (-CD), polyvinyl alcohol (PVA), polyvinyl pyrrolidone K-30 (PVP K-30), cross-linkers including dichloromethane (DCM), dimethyl carbonate (DMC), glutaraldehyde (GTLD), stabilisers including kondagogu gum (kgg), olibanum gum (OLG), and solvents like ethanol, methanol, dimethyl sulfoxide (DMSO), dimethyl formamide (DMF), dist. water etc were used with different proportion with respective methods of preparation. Emulsion Ultrasonic-assisted synthesis, solve
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Conference papers on the topic "PVP K-30"

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Hadley, Isabel, Bob Ainsworth, Peter Budden, and John Sharples. "The Future of the BS 7910 Flaw Assessment Procedures." In ASME 2010 Pressure Vessels and Piping Division/K-PVP Conference. ASMEDC, 2010. http://dx.doi.org/10.1115/pvp2010-25582.

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BS 7910, the UK procedure for the assessment of flaws in metallic structures, was first published some 30 years ago in the form of a fracture/fatigue assessment procedure, PD6493. Since then it has been regularly maintained and expanded, taking in elements of other publications such as the UK power industry’s ‘R6’ procedure (in particular the Failure Assessment Diagram or FAD approach), the creep assessment procedure PD6539 and the UK gas transmission industry’s approach to corrosion assessment of locally thinned areas in pipelines. Work is currently underway to prepare another major revision,
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Wu, Tsu-te, Narendra K. Gupta, Allen C. Smith, and Paul S. Blanton. "A Method for the Coupled Thermal-Structural Analysis of Radioactive Material Shipping Packages in Hypothetical Accident Conditions: Part 1—NCT Thermal Load and Some HAC Mechanical Loads." In ASME 2010 Pressure Vessels and Piping Division/K-PVP Conference. ASMEDC, 2010. http://dx.doi.org/10.1115/pvp2010-25956.

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The design of radioactive material (RAM) shipping packages are designed to withstand the mechanical and thermal loads specified in Title 10 Code of Federal Regulations Part 71 (10CFR71). The Hypothetical Accident Conditions (HAC) specified in 10CFR71 include a 30-foot free drop, a crush by an 1100-pound plate, a 40-inch free drop onto a round bar and a 30-minite fire. Furthermore, in accordance with the Nuclear Regulatory Commission Guide 7.8, these loads should be applied sequentially. The current common practice is to base the thermal modeling on the un-deformed (or un-damaged) packaging con
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Hoesing, Mitchell P., and Gregory J. Michna. "Integration of a Pulsating Heat Pipe in a Flat Plate Heat Sink." In ASME 2014 12th International Conference on Nanochannels, Microchannels, and Minichannels collocated with the ASME 2014 4th Joint US-European Fluids Engineering Division Summer Meeting. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/icnmm2014-21233.

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The ongoing development of faster and smaller electronic components has led to a need for new technologies to effectively dissipate waste thermal energy. The pulsating heat pipe (PHP) shows potential to meet this need, due to its high heat flux capacity, simplicity, and low cost. A 20-turn flat plate PHP was integrated into an aluminum flat plate heat sink with a simulated electronic load. The PHP heat sink used water as the working fluid and had 20 parallel channels with dimensions 2 mm × 2 mm × 119 mm. Experiments were run under various operating conditions, and thermal resistance of the PHP
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Chiu, Chong, and Lance B. Gockel. "Iatan Desuperheater Pipe Failure Caused by FAC: September 28, 2007." In ASME 2010 Pressure Vessels and Piping Division/K-PVP Conference. ASMEDC, 2010. http://dx.doi.org/10.1115/pvp2010-26066.

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At approximately 11:40 AM on May 9, 2007, Iatan Unit 1 experienced a catastrophic rupture of a 4 inch superheater (SH) attemperator spray line after nearly 27 years of commercial operations. At the time of the rupture, several plant personnel were in the immediate vicinity performing maintenance on a plugged coal feeder. Plant operators immediately initiated a plant shutdown. This incident resulted in two fatalities and one serious injury. Subsequent examination of the ruptured line indicated significant pipe wall thinning had occurred, leading to the sudden failure of the pipe pressure bounda
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Kikuchi, Masanori, Yoshitaka Wada, and Chikako Ohdama. "Effect of KIII on Fatigue Crack Growth Behavior." In ASME 2010 Pressure Vessels and Piping Division/K-PVP Conference. ASMEDC, 2010. http://dx.doi.org/10.1115/pvp2010-25197.

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Mixed mode fatigue tests are conducted using surface cracked specimen. Slant surface cracked specimens are made where crack angle is 15°, 30°, 45° and 60°. It is shown that factory roof is made at deepest point of surface crack due to ΔKIII, and crack growth rate decreases by the factory roof. Fatigue crack growth is simulated using S-version FEM (Finite Element Method) using crack growth criteria. It is shown that conventional crack growth criteria are not available to predict fatigue crack growth with factory roof. In this study, modified criterion for the prediction of crack growth rate is
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EL-Bagory, Tarek M. A. A., Maher Y. A. Younan, Hossam E. M. Sallam, and Lotfi A. Abdel-Latif. "Effect of Load Angle on Limit Load of Polyethylene Miter Pipe Bends." In ASME 2010 Pressure Vessels and Piping Division/K-PVP Conference. ASMEDC, 2010. http://dx.doi.org/10.1115/pvp2010-25491.

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The aim of this paper is to investigate the effect crack depth a/W = 0 to 0.4 and load angle (30°,45°,and 60°) on the limit load of miter pipe bends (MPB) under out-of-plane bending moment with a crosshead speed 500 mm/min. The geometry of cracked and uncracked multi miter pipe bends are: bend angle, α = 90°, pipe bend factor, h = 0.844, standard dimension ratio, SDR = 11, and three junctions, m = 3. The material of the investigated pipe is a high-density polyethylene (HDPE), which is applied in natural gas piping systems. Butt-fusion welding is used to produce the welds in the miter pipe bend
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Melo, Jose Daniel D., and Jeffrey T. Fong. "A New Approach to Creating Composite Materials Elastic Property Database With Uncertainty Estimation Using a Combination of Mechanical and Thermal Expansion Tests." In ASME 2010 Pressure Vessels and Piping Division/K-PVP Conference. ASMEDC, 2010. http://dx.doi.org/10.1115/pvp2010-26144.

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In composite structural design, a fundamental requirement is to furnish the designer with a set of elastic constants. For example, to design for a given temperature a laminate consisting of transversely isotropic fiber-reinforced laminae, we need five independent elastic constants of each lamina of interest, namely, E1, E2, ν12, G12, and ν23. At present, there exist seven tests, two of mechanical-lamina, two of thermal-expansion-lamina, and three of thermal-expansion-laminate types, to accomplish this task. It is known in the literature that the mechanical tests are capable of measuring E1, E2
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Tateno, Masayoshi, and Hiroki Morikawa. "Relationship Between Singularity Strength Factors and Practical Bonding Strength of Ceramic to Metal Joint." In ASME 2010 Pressure Vessels and Piping Division/K-PVP Conference. ASMEDC, 2010. http://dx.doi.org/10.1115/pvp2010-25431.

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This study correlates the stress intensity factors (Kii, Kpaii), the order of the stress singularity p-1, and the practical bonding strength of ceramic to metal joints with arbitrary interface geometry. First, in order to describe the stress behavior of TiB2 to Ni joints bonded at 1173K, the stress singularity factors (Kii, Kpaii, p-1) were theoretically derived for wedge angles of φ1:30°&amp;lt;φ1&amp;lt;150°. Secondly, the dependences of the singularity factors on the wedge angle φ1 were compared with experimental results using the same wedge angles on TiB2 to Ni joints with interface convex
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Conway, Jennifer M., Anthony R. Ortiz, Stanley E. Jones, Viola Acoff, and Xiu Bu. "Perforation Testing of a Titanium Alloy Target Using Hardened 4340 Steel Projectiles." In ASME 2010 Pressure Vessels and Piping Division/K-PVP Conference. ASMEDC, 2010. http://dx.doi.org/10.1115/pvp2010-25025.

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A perforation test, originally devised for composites and other materials that do not lend themselves easily to more conventional high strain rate testing procedures, is applied to a titanium alloy. In this test, cylindrical projectiles of hardened 4340 steel are launched from a smooth bore powder gun at velocities ranging from 50 m/s to 350 m/s. The projectiles have conical noses with pitch angles that vary from 90° to 30°. These projectiles impact the titanium alloy target at normal incidence and perforate it. After perforating the target, the projectiles are caught in a sand barrier. Based
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Gardner, Christopher, Rajeev Madazhy, and Erik Howard. "Analysis of Contact Pressure Distribution on a Pass Partition Gasket in Conjunction With a Double-Tapered Seal in a High Pressure Heat Exchanger Closure." In ASME 2010 Pressure Vessels and Piping Division/K-PVP Conference. ASMEDC, 2010. http://dx.doi.org/10.1115/pvp2010-26157.

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This paper describes the use of a partition gasket in addition to a self-energized, double-tapered, metal seal in a high pressure heat exchanger. For over 30 years a single gasket was used to seal the heat exchanger partitions against the closure. Although designed to standard code, it often resulted in leaks. Over the past five years, the double-tapered seal has been used extensively to replace welded diaphragms in high pressure heat exchangers in refineries with great success. In this design a tapered-seal is introduced in conjunction with a pass partition gasket for multiple pass heat excha
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