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Relevant bibliographies by topics / PVP K90 and HPMC E 15

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Journal articles

Academic literature on the topic 'PVP K90 and HPMC E 15'

Author: Grafiati

Published: 3 June 2025

Last updated: 1 August 2025

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Journal articles on the topic "PVP K90 and HPMC E 15"

1

Perumalla, Ashok Kumar 1. *. Dr. Deenanath Jhade 2. "FORMULATION AND INVITRO EVALUATION OF RIZATRIPTAN ORAL THIN FILMS." Journal of Scientific Research in Pharmacy 7, no. 7 (2018): 74–78. https://doi.org/10.5281/zenodo.1318318.

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<strong><em>ABSTRACT</em></strong> <strong><em>I</em></strong><em>n present study oral thin films of Rizatriptan was developed to have a faster on set of action. The oral thin films were developed by using polymers HPMC E5, HPMC E 15 and PVP K90.Oral thin films were prepared by employing solvent casting method. Propylene glycol was selected as permeation enhancer and plasticizer. Drug excipient compatibility studies were carried out by using FTIR, and it was observed that there were no interactions. Formulations were prepared with the varying concentrations polymers ranging from F1-F12, and al

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2

Nerker, Pankaj P., Hitendra Mahajan, Sagar Deore, and Pradyumn Ige. "Formulation and Evaluation of Nanosuspension Formulations of Ramipril using Hydrophilic Polymers." International Journal of Pharmaceutical Sciences and Nanotechnology 8, no. 1 (2015): 2735–41. http://dx.doi.org/10.37285/ijpsn.2015.8.1.5.

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 Nanosuspensions provide convenient formulations for improving the bioavailability and drug delivery. The objective of the investigation was to develop stable nanosuspension formulation of ramipril, with minimum surfactant concentration that could improve its solubility, stability and oral bioavailability. Ramipril is a potent antihypertensive drug, which act by inhibiting the angiotensin-converting enzyme. Nanosuspension was developed by antisolvent precipitation followed by high-pressure homogenization using hydrophilic polymers such as HPMC E5, HPMC E15, PVP K30, PVP K25, and PVA. The

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3

Rohit, Ajay, Mukesh Kumar Patel, and Ashish Manigauha. "Formulation Development and Evaluation of Bilayer Tablet for Effective Treatment of Gastric Ulcer." Journal of Drug Delivery and Therapeutics 9, no. 3-s (2019): 705–10. http://dx.doi.org/10.22270/jddt.v9i3-s.2960.

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The present study was aimed at developing Gastro retentive bilayer drug delivery systems containing esomeprazole and clarithromycin for the treatment of H. pylori induced gastric ulcer to minimize the side effect, improve the prolongation of action, to reduce the frequency of drug administration. The tablet is characterized by immediate release layer of esomeprazole and Gastroretentive layer of clarithromycin. The formulation containing Gastroretentive layer was designed using HPMC K 15, HPMC K4 and PVP K30 as floating agents, sodium bicarbonate and citric acid as gas-generating agent. Crospov

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4

Gönüllü, Ü., P. Gürpınar, and M. Üner. "Double-layer Tablets of Lornoxicam: Validation of Quantification Method, In vitro Dissolution and Kinetic Modelling." Tropical Journal of Pharmaceutical Research 14, no. 9 (2015): 1659–66. http://dx.doi.org/10.4314/tjpr.v14i9.16.

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Purpose: To formulate double-layer tablets of lornoxicam (LRX) prepared by direct compression method and evaluate their physical and drug release characteristics.Methods: The outer layer of tablets, composed of microcrystalline cellulose (MCC), starch and lactose, incorporated tan initial or prompt dose of the drug (4 mg) for immediate release. Hydroxypropyl methylcellulose (HPMC), polyvinylpyrrolidone (PVP K90) and carbomer, in varying concentrations, were used to prepare the tablet cores for sustained drug delivery. Weight variation, dimensions, hardness, tensile strength, friability and dis

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5

Kushwaha, Jeetendra, Dev Sharan Chaturvedi, Manisha Verma, Kuldeep Kumar Tiwari, and Neelesh Anuragi. "FORMULATION DEVELOPMENT AND EVALUATION OF MATRIX TABLET TRAZODONE HYDROCHLORIDE USING NATURAL POLYMER." International Research Journal Of Pharmacy 12, no. 8 (2021): 46–51. http://dx.doi.org/10.7897/2230-8407.1208156.

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Increased complications and costs of marketing of innovative drugs focused greater attention to the development of sustained release (SR) or controlled release (CR) drug delivery systems. Trazodone Hydrochloride (TRZ) is a well-known chemical compound that is used as an antidepressant that belongs to a selective serotonin reuptake inhibitor (SARI). The objective of present work was to develop and evaluated oral sustained release matrix tablet of TRZ. Pre-compression parameters were evaluated. The tablets were evaluated for post-compression parameters such as thickness, hardness, average weight

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6

Duyên, Huỳnh Thị Mỹ, та Lê Thị Minh Ngọc. "NGHIÊN CỨU BÀO CHẾ VIÊN NÉN NỔI CLARITHROMYCIN 500 MG". TNU Journal of Science and Technology 229, № 09 (2024): 29–35. http://dx.doi.org/10.34238/tnu-jst.8953.

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Tỷ lệ bệnh viêm loét dạ dày ngày một tăng cao trên thế giới, trong đó có Việt Nam. Một trong những nguyên nhân hàng đầu gây ra bệnh lý trên là do bị nhiễm Helicobacter pylori, đây là loại vi khuẩn sống ở niêm mạc và lớp dưới niêm mạc dạ dày - tá tràng. Do đó để tăng hiệu quả điều trị, thuốc cần lưu lại dạ dày trong thời gian lâu để thấm sâu vào niêm mạc. Clarithromycin được đưa vào các phát đồ điều trị H. pylori, tuy nhiên clarithromycin có thời gian bán thải ngắn nên phải sử dụng nhiều lần trong ngày, gây ra những tác dụng ngoại ý cho bệnh nhân. Thuốc nổi là một trong những dạng bào chế mới,

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7

Chaiwarit, Tanpong, Baramee Chanabodeechalermrung, Pensak Jantrawut, Warintorn Ruksiriwanich, and Mathukorn Sainakham. "Fabrication and Characterization of Dissolving Microneedles Containing Oryza sativa L. Extract Complex for Enhancement of Transfollicular Delivery." Polymers 16, no. 16 (2024): 2377. http://dx.doi.org/10.3390/polym16162377.

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Dissolving microneedles are extensively applied in drug delivery systems to enhance penetration into the skin. In this study, dissolving microneedles fabricated from polyvinylpyrrolidone K90 (PVP-K90) and hydroxypropylmethyl cellulose (HPMC) E50 in different ratios were characterized. The selected formulations incorporated Oryza sativa L. extract complex and its characteristics, transfollicular penetration, and safety were observed. The microneedles, fabricated from PVP K90: HPMC E50 in a ratio of 25:5 (P25H5) and 20:10 (P20H10), revealed excellent morphological structure, proper mechanical st

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8

Chanabodeechalermrung, Baramee, Tanpong Chaiwarit, Siripat Chaichit, et al. "HPMC/PVP K90 Dissolving Microneedles Fabricated from 3D-Printed Master Molds: Impact on Microneedle Morphology, Mechanical Strength, and Topical Dissolving Property." Polymers 16, no. 4 (2024): 452. http://dx.doi.org/10.3390/polym16040452.

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Three-dimensional (3D) printing can be used to fabricate custom microneedle (MN) patches instead of the conventional method. In this work, 3D-printed MN patches were utilized to fabricate a MN mold, and the mold was used to prepare dissolving MNs for topical lidocaine HCl (L) delivery through the skin. Topical creams usually take 1–2 h to induce an anesthetic effect, so the delivery of lidocaine HCl from dissolving MNs can allow for a therapeutic effect to be reached faster than with a topical cream. The dissolving-MN-patch-incorporated lidocaine HCl was constructed from hydroxypropyl methylce

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9

Suhaidi, Danni, Yao-Da Dong, Paul Wynne, Karen P. Hapgood, and David A. V. Morton. "Bulk Flow Optimisation of Amorphous Solid Dispersion Excipient Powders through Surface Modification." Pharmaceutics 15, no. 5 (2023): 1447. http://dx.doi.org/10.3390/pharmaceutics15051447.

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Particulate amorphous solid dispersions (ASDs) have been recognised for their potential to enhance the performance of various solid dose forms, especially oral bioavailability and macromolecule stability. However, the inherent nature of spray-dried ASDs leads to their surface cohesion/adhesion, including hygroscopicity, which hinders their bulk flow and affects their utility and viability in terms of powder production, processing, and function. This study explores the effectiveness of L-leucine (L-leu) coprocessing in modifying the particle surface of ASD-forming materials. Various contrasting

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10

Bhardi, Shashank S., Vidhyashree B, Arvinder Kaur, and Preethi G B. "Development and Evaluation of Polymeric Film Forming Solution of Ciclopirox Olamine for Topical Fungal Therapy." Journal of Advances in Medical and Pharmaceutical Sciences 27, no. 5 (2025): 65–77. https://doi.org/10.9734/jamps/2025/v27i5778.

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Aim: Formulation and assessment of polymeric film forming solution (PFFS) loaded with Ciclopirox olamine (CPO) for managing topical fungal infections. Methods: PFFS was prepared using a common solvent method with a range of polymers, such as Eudragit RL 100, Eudragit RS 100, PVP K30, PVP K90, HPC, HPMC K15, HPMC K4M, and PEG 400 in ethanol. The formulated PFFS was evaluated for Physicochemical properties, In vitro drug release, ex vivo permeation studies, stability studies, and antifungal assay. Results: The formulations have exhibited drying time of less than one minute. Most of them demonstr

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