Academic literature on the topic 'Pyrazine'

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Journal articles on the topic "Pyrazine"

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Hrynyshyn, Yevhenii, Hanna Musiichuk, Olena Komarovska-Porokhnyavets, et al. "Synthesis and Antimicrobial Activity of 4-Arylthio- and 4 Alkylthiofunctionalized Pyrazolo[1,5-a]pyrazines." Ukrainian Chemistry Journal 85, no. 1 (2019): 58–66. http://dx.doi.org/10.33609/0041-6045.85.1.2019.58-66.

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The reaction of pyrazolo[1,5-a]pyrazine-4(5H)ones with phosphorus tribromoxide in boiling benzene yielded 4-bromopyrazolo[1,5-a]pyrazines, and the thionation with phosphorus pentasulfide in pyridine at 90 °C led to pyrazolo[1,5-a]pyrazine-4(5H)thiones. The synthesized bromine derivatives are electrophilic, and thiones are nucleophilic substrates. Their subsequent structural modification in the first case was carried out by interaction with thiophenols, and in the second case was conducted with functional halogenoalkanes. It was shown that bromides react with substituted thiophenols in dimethyl
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Kučerová-Chlupáčová, Marta, Veronika Opletalová, Josef Jampílek, et al. "New Hydrophobicity Constants of Substituents in Pyrazine Rings Derived from RP-HPLC Study." Collection of Czechoslovak Chemical Communications 73, no. 1 (2008): 1–18. http://dx.doi.org/10.1135/cccc20080001.

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Pyrazine derivatives show a wide range of biological activities. 1-Pyrazin-2-ylethan-1-ones have served as food flavourants, and together with pyrazine-2-carbonitriles have been widely used as intermediates in the synthesis of various heterocyclic compounds. In our laboratory, substituted pyrazine-2-carbonitriles and 1-pyrazin-2-ylethan-1-ones have been used as intermediates for the preparation of potential antifungal and antimycobacterial drugs. Using established methods, a library of pyrazine derivatives was synthesized. Homolytic alkylation of commercially available pyrazine-2-carbonitrile
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Tong, Wenhua, Shuqin Wang, Haoran Xu, Zongwei Qiao, Liming Zhao, and Ying Yang. "Interaction and Binding Kinetics of Different Substituted Pyrazines with HSA: Based on Multispectral, Physiological Activity, and Molecular Dynamics Simulations." Journal of Food Biochemistry 2024 (March 25, 2024): 1–20. http://dx.doi.org/10.1155/2024/4373558.

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Pyrazine is a kind of compound containing pyrazine ring structure, which has attracted the attention of researchers because of its special aroma and healthcare function. It is currently used in spices, pharmaceuticals, food additives, and other industries. Human serum albumin (HSA) is a transport and storage protein in the human circulatory system. Previous research reported that pyrazine can interact with albumin, but the interaction between pyrazine and HSA has not been reported. Consequently, this study is based on the multispectral method and molecular dynamics (MD) simulation, exploring t
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Lassagne, Frédéric, Timothy Langlais, Elsa Caytan, et al. "From Quinoxaline, Pyrido[2,3-b]pyrazine and Pyrido[3,4-b]pyrazine to Pyrazino-Fused Carbazoles and Carbolines." Molecules 23, no. 11 (2018): 2961. http://dx.doi.org/10.3390/molecules23112961.

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2,3-Diphenylated quinoxaline, pyrido[2,3-b]pyrazine and 8-bromopyrido[3,4-b]pyrazine were halogenated in deprotometalation-trapping reactions using mixed 2,2,6,6-tetramethyl piperidino-based lithium-zinc combinations in tetrahydrofuran. The 2,3-diphenylated 5-iodo- quinoxaline, 8-iodopyrido[2,3-b]pyrazine and 8-bromo-7-iodopyrido[3,4-b]pyrazine thus obtained were subjected to palladium-catalyzed couplings with arylboronic acids or anilines, and possible subsequent cyclizations to afford the corresponding pyrazino[2,3-a]carbazole, pyrazino[2′,3′:5,6] pyrido[4,3-b]indole and pyrazino[2′,3′:4,5]p
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Ma, Yun-Jiao, Jian-Hai Wu, Xiang Li, et al. "Effect of alkyl distribution in pyrazine on pyrazine flavor release in bovine serum albumin solution." RSC Advances 9, no. 63 (2019): 36951–59. http://dx.doi.org/10.1039/c9ra06720e.

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The methyl groups on the pyrazine ring affect the interaction of pyrazines with BSA. The non-covalent interaction between alkyl-pyrazines and BSA was confirmed. Alkyl-pyrazines could induce the polarity and conformation change of BSA.
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Buděšínský, Miloš, Antonín Trka, Karel Stránský, and Milan Streibl. "Heterocyclic nitrogen-containing compounds from the extract of the springtail Tetrodontophora bielanensis (WAGA)." Collection of Czechoslovak Chemical Communications 51, no. 4 (1986): 956–63. http://dx.doi.org/10.1135/cccc19860956.

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Two pyrido[2,3-b]pyrazines were isolated from the extract of the springtail Tetrodontophora bielanensis (WAGA). Their structure were determined by mass and NMR spectroscopy: 2,3-dimethoxypyrido[2,3-b]pyrazine (I) and 2-methoxy-3-isopropylpyrido[2,3-b]pyrazine (II).
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Jigajinni, V. B., P. N. Preston, V. K. Shah, S. W. Simpson, I. Soutar, and N. J. Stewart. "Structure-property relationships in PMR-15-type polyimide resins: IIH. New polyimides incorporating triazoles, quinoxalines, pyridopyrazines and pyrazinopyridazines." High Performance Polymers 5, no. 3 (1993): 239–57. http://dx.doi.org/10.1088/0954-0083/5/3/008.

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Polyimide oligomers (prepolymers) and resins of the PMR-15 type have been prepared from 5-norbomene-2,3-dicarboxylic half acid ester (NE), 3,3',4,4'-benzophenone tetracarboxylic diester (BTDE) and a series of diamines incorporating 1,2,3-triazole, quinoxaline, pyrido[2,3-b]pyrazine, pyrido[3,4-b]pyrazine, benzo[g]quinoxaline, pyrazino-[2,3]-d]pyridazine and bis(pyrido[3,4-b]pyrazino)benzene ring systems. Two tetraamines in the bis(pyrazino[2,3-d]pyridazino)benzene ring system were also employed. Selected diamine monomers from the above ring systems provde PMR-15-analogue resins of higher therm
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Ashraf-Khorassani, Mehdi, William M. Coleman, Michael F. Dube та Larry T. Taylor. "Optimization of α-Hydroxyketone and Pyrazine Syntheses Employing Preliminary Reactions of Glucose and Buffer Solutions". Beiträge zur Tabakforschung International/Contributions to Tobacco Research 28, № 7 (2019): 329–39. http://dx.doi.org/10.2478/cttr-2019-0014.

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SummaryGlucose and selected phosphate buffers have been reacted employing systematic variations in reaction temperature and time (150–160 °C for 60–90 min) to optimize the yield of acetol. This mixture was reacted further with NH4OH, systematically varying reaction conditions and reagent ratios to optimize pyrazine yield. The highest yield of pyrazine was obtained when 1 g of glucose was reacted with 25 mL of buffer at 150–160 °C for 60 min, which in turn was reacted with 1 mL of concentrated aqueous NH4OH at 120–130 °C for 17–18 h. Higher temperatures and higher concentrations of glucose caus
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Wang, Furong, Hailiang Shen, Ting Liu, Xi Yang, Yali Yang, and Yurong Guo. "Formation of Pyrazines in Maillard Model Systems: Effects of Structures of Lysine-Containing Dipeptides/Tripeptides." Foods 10, no. 2 (2021): 273. http://dx.doi.org/10.3390/foods10020273.

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At present, most investigations involving the Maillard reaction models have focused on free amino acids (FAAs), whereas the effects of peptides on volatile products are poorly understood. In our study, the formation mechanism of pyrazines, which were detected as characteristic volatiles in sunflower seed oil, from the reaction system of glucose and lysine-containing dipeptides and tripeptides was studied. The effect of the amino acid sequences of the dipeptides and tripeptides on pyrazine formation was further highlighted. Four different dipeptides and six tripeptides were selected. The result
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Zang, Binbin, та Lihui Wang. "Synthesis and protective effect of pyrazole conjugated imidazo[1,2-a]pyrazine derivatives against acute lung injury in sepsis rats via attenuation of NF-κB, oxidative stress, and apoptosis". Acta Pharmaceutica 73, № 3 (2023): 341–62. http://dx.doi.org/10.2478/acph-2023-0031.

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Abstract The current work was conducted to elucidate the pharmacological effect of pyrazole-conjugated imidazo[1,2-a]pyrazine derivatives against acute lung injury in rats in sepsis and their mechanism of action. Various pyrazole-conjugated imidazo[1,2-a]-pyrazine derivatives have been synthesized in a straightforward synthetic route. They exhibited a diverse range of inhibitory activity against NF-ĸB with IC 50 ranging from 1 to 94 µmol L–1. Among them, compound 3h [(4-(4-((4-hydroxyphenyl)sulfonyl) phenyl)-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl) (8-(methylamino)imidazo[1,2-a]pyrazin
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Dissertations / Theses on the topic "Pyrazine"

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Carroll, John Robert. "Selectivity and enantioselectivity in the palladium catalysed hydrogenation of pyrazine and some substituted pyrazines." Thesis, University of Hull, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.342963.

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Prunier, Hervé. "Synthèse et étude physicochimique de nouvelles pyrrolo [1,2-α] pyrazines à visée sérotoninergique". Caen, 1996. http://www.theses.fr/1996CAEN4059.

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Blache, Yves. "Hétérocyclisation en séries quinoxalinique et pyrido[2,3-b]pyrazinique : synthèse, structure, réactivité." Montpellier 1, 1991. http://www.theses.fr/1991MON13508.

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Dias, Sandra Isabel Godinho. "Synthesis and supramolecular phenomenon of novel pyrazine derivatives." Thesis, University of Kent, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.429799.

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Lancelot, Jean-Charles. "Synthèse et étude physicochimique des pyrido (3,2-e) pyrrolo (1,2-a) pyrazines, pyrido (2,3-e) pyrrolo (1,2-a) pyrazines, pyrazino (2,3-e) pyrrolo (1,2-a) pyrazines, (pyrrolyl-1)-8 triazolo-1, 2, 4 (4,3-a) pyridines, 6H-pyrido (2,3-c) pyrrolo (1,2-e) triazépines-1,2,5, pyrido (2,3-h) pyrrolo (1,2-a) quinoxalines." Caen, 1989. http://www.theses.fr/1989CAEN4023.

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Munro, Bruce F. "Acoustic emission from the synthesis of dichloro(pyrazine)zinc(II)." Thesis, University of British Columbia, 1991. http://hdl.handle.net/2429/30138.

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The reaction of pyrazine with ZnCl₂ m aqueous solution results in copious acoustic emission in the ultrasonic region. When first reported, no satisfactory explanation was given for this observation. The aims of this thesis are to determine the source of the acoustic emission and, where possible, to establish experimental relationships between the system's chemical and physical properties and its acoustic emission. The detection system used consisted of a piezoelectric transducer mounted beneath the reaction vessel. Its conditioned output was connected to a peak acoustic emission intensity int
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Saab, Mohamad Yehia. "Photochimie organique guidée par pulses laser : Applications : Benzopyrane et Pyrazine." Thesis, Montpellier 2, 2014. http://www.theses.fr/2014MON20014/document.

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La photo-isomérisation par ouverture de cycle du benzopyrane a été étudiée à l'aide de la méthode MCTDH (Multi-Configuration Time-Dependent Hartree). Nous avons introduit différentes stratégies pour contrôler la conversion du benzopyrane en mérocyanine à l'aide d'impulsions laser. Nous avons utilisé un modèle pour le potentiel électronique à six dimensions développé dans le cadre d'un travail antérieur. Le modèle repose sur une généralisation des Hamiltoniens modèles standards pour les couplages vibroniques et utilise les six coordonnées les plus importantes pour le processus. Le principal obj
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Tembo, Norbert Olivier. "Synthèse et étude physicochimique des 4-amino-1, 2, 3, 4-tétrahydro-1-isoquinolones et 2-quinolones ; 4-aryl-2, 3-dihydropyrrolizines ; 4-aryl-1-oxo-1, 2, 3, 4-tétrahydro-pyrrolo [1, 2-a] pyrazines ; 4-aryl-2-imidazolidinones." Caen, 1990. http://www.theses.fr/1990CAEN4044.

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Mojovic, Ljubica. "Métallations et synthèses en série pyrazinique et pyridazinique." Rouen, 1990. http://www.theses.fr/1990ROUES033.

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Nous avons appliqué pour la première fois, la réaction de métallation à la synthèse de dérivés de la pyrazine et de la pyridazine. Ces composés nous ont permis d'effectuer des réactions de couplage catalysées par le palladium et de préparer des analogues en série diaziniques de composés biologiquement actifs: diazépines, xanthones. Nous avons proposé une nouvelle voie d'accès a un produit pharmaceutique connu
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Thamyongkit, Patchanita. "Synthesis and characterization of pyrazine and phthalocyaninatonickel(II) substituted PPV analogous oligomers Synthese und Charakterisierung von Pyrazin- und Phthalocyaninatonickel(II)-substituierten PPV-anologen Oligomeren /." [S.l. : s.n.], 2001. http://deposit.ddb.de/cgi-bin/dokserv?idn=963899929.

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Books on the topic "Pyrazine"

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Wright, Sarah Margaret Anne. Vibrational energy transfer in polyatomic molecules: Collisions of highly excited pyrazine, toluene and nitrosyl cyanide with helium, argon and nitrogen. University of Birmingham, 2000.

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Brown, D. J. The Pyrazines. John Wiley & Sons, Inc., 2002. http://dx.doi.org/10.1002/0471244295.

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Lange, Pieter J. de. Cold molecules in a supersonic expansion: Experiments on clusters in a supersonic beam theory of radiationless transitions and the spectroscopy of pyrazine. Drucker:] Krips Repro, 1989.

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Mayer, Michael. Farbe und Konstitution bei H-Chelaten der Pyrazinreihe: Präparative und spektroskopische Untersuchungen. Hartung-Gorre, 1985.

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Juvonen, Risto O. Pyrazole as a modifier of cytochrome P450 dependent coumarin 7-hydroxylase (P450Coh) in DBA/2 mice: Purification, characterization and genetic regulation. Kuopion yliopisto, 1989.

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Anderson, Kenneth C., Paul G. Richardson, and Irene M. Ghobrial. Bortezomib in the treatment of multiple myeloma. Springer, 2010.

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Simpson, J. C. Pyridazine and Pyrazine Rings : (Cinnolines, Phthalazines, and Quinoxalines). Wiley & Sons, Incorporated, John, 2009.

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Simpson, J. C. Chemistry of Heterocyclic Compounds, Pyridazine and Pyrazine Rings. Wiley & Sons, Incorporated, John, 2008.

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Cremer, Frank. Synthese neuer Piracetam-Analoga und arylsubsitituierter Pyrrolo[1,2-a]pyrazine. 1997.

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Wu, Xiao-Feng, and Zechao Wang. Transition Metal Catalyzed Pyrimidine, Pyrazine, Pyridazine and Triazine Synthesis: Transition Metal-Catalyzed Heterocycle Synthesis Series. Elsevier, 2016.

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Book chapters on the topic "Pyrazine"

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Dave, Pragnesh. "Purine-, Pyran-, Pyrazole-, and Pyrazine-based Corrosion Inhibitors." In Handbook of Heterocyclic Corrosion Inhibitors. CRC Press, 2023. http://dx.doi.org/10.1201/9781003377016-7.

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Zviely, Michael, Elias Abushqara, and Danny Hodrien. "Chocarom Pyrazine: A Remarkable Pyrazine for Flavors and Fragrances." In ACS Symposium Series. American Chemical Society, 2005. http://dx.doi.org/10.1021/bk-2005-0908.ch013.

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Weenen, H., S. B. Tjan, P. J. de Valois, N. Bouter, A. Pos, and H. Vonk. "Mechanism of Pyrazine Formation." In Thermally Generated Flavors. American Chemical Society, 1993. http://dx.doi.org/10.1021/bk-1994-0543.ch012.

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Brolo, A. G., and D. E. Irish. "The Behavior of Pyrazine and Monoprotonated Pyrazine Adsorbed on Silver Electrodes." In ACS Symposium Series. American Chemical Society, 1997. http://dx.doi.org/10.1021/bk-1997-0656.ch022.

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Winkelmann, Jochen. "Self-diffusion coefficient of pyrazine." In Diffusion in Gases, Liquids and Electrolytes. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-540-73735-3_103.

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Plé, Nelly, and Corinne Fruit. "Metalation of Pyrazine and Quinoxaline." In Topics in Heterocyclic Chemistry. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/7081_2012_95.

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Winkelmann, Jochen. "Diffusion coefficient of pyrazine in ethanol." In Diffusion in Gases, Liquids and Electrolytes. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-540-73735-3_448.

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Winkelmann, Jochen. "Diffusion coefficient of pyrazine in ethanol." In Diffusion in Gases, Liquids and Electrolytes. Springer Berlin Heidelberg, 2018. http://dx.doi.org/10.1007/978-3-662-54089-3_269.

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Demaison, J. "443 C4H6N2O Pyrazine - water (1/1)." In Asymmetric Top Molecules. Part 2. Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-10400-8_191.

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Hanack, M., and A. Leverenz. "Doping Experiments with μ-(Pyrazine)phthalocyaninatoiron(II)." In Springer Series in Solid-State Sciences. Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/978-3-642-83284-0_59.

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Conference papers on the topic "Pyrazine"

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Chen, Yi-Ting, Guan-Yu Su, Chih-Hao Chang, et al. "Thermally Activated Delayed Fluorescent and Fluorescent Emitters Based on Pyrazino[2,3-f] [1], [10]Phenanthroline for Efficient Organic Light-Emitting Diodes." In 2024 31st International Workshop on Active-Matrix Flatpanel Displays and Devices (AM-FPD). IEEE, 2024. http://dx.doi.org/10.23919/am-fpd61635.2024.10615767.

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Salim, Muath Bani, Reza Nekovei, Tamer Elwaie, and Jeyakumar Ramanujam. "Development of Heterocyclic-C61-butyric Acid Methyl Ester/ Pyrazine (HCBM-Pyrazine) acceptor material for organic solar cells applications." In 2019 IEEE 19th International Conference on Nanotechnology (IEEE-NANO). IEEE, 2019. http://dx.doi.org/10.1109/nano46743.2019.8993877.

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Saraswat, Mayank, and Sugumar Venkataramani. "MATRIX-ISOLATION FTIR SPECTROSCOPY OF THE DEHYDRO-PYRAZINE RADICAL." In 74th International Symposium on Molecular Spectroscopy. University of Illinois at Urbana-Champaign, 2019. http://dx.doi.org/10.15278/isms.2019.fd02.

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Jordis, Ulrich, and Sagar Beldar. "Synthetic studies towards the antiviral pyrazine derivative T-705." In The 13th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2009. http://dx.doi.org/10.3390/ecsoc-13-00223.

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Li, Changqing, Guoping Zhang, Jinhui Li, and Yingying Li. "Low Temperature Curing Copolyimide with Monomer Containing Pyrazine Moiety." In 2021 22nd International Conference on Electronic Packaging Technology (ICEPT). IEEE, 2021. http://dx.doi.org/10.1109/icept52650.2021.9568094.

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Doležal, Martin, Jiří Kuneš, Josef Jampílek, and Stanislav Bielesz. "Substituted pyrazine-2,5-dicarboxamides: Synthesis, Hydrophobicity Parameters, and Antimycobacterial Evaluation." In The 11th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2007. http://dx.doi.org/10.3390/ecsoc-11-01340.

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Ligiéro, Carolina B. P., Luis G. T. A. Duarte, and Paulo C. M. L. Miranda. "Synthesis of Tetra(imidazoil-4(5)-yl)pyrazine and Tetrapyrazilpyrazine." In 14th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0208-1.

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Li, Yan, and Xiao-Shuang Ma. "Optical properties of pyrazine derivatives compared with their s-triazine analogs." In 6th International Conference on Mechatronics, Materials, Biotechnology and Environment (ICMMBE 2016). Atlantis Press, 2016. http://dx.doi.org/10.2991/icmmbe-16.2016.23.

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Collette, Jeremy C., and Aaron W. Harper. "Properties and chemical environment effects of alkylamino styryl pyrazine two-photon fluorophores." In Optical Science and Technology, SPIE's 48th Annual Meeting, edited by Mark G. Kuzyk, Manfred Eich, and Robert A. Norwood. SPIE, 2003. http://dx.doi.org/10.1117/12.505065.

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Kanno, Manabu, Yuta Ito, Noriyuki Shimakura, Shiro Koseki, Hirohiko Kono, and Yuichi Fujimura. "Ab Initio Quantum Dynamical Study on Ultrafast Nonradiative Transition Pathways of Pyrazine." In International Conference on Ultrafast Phenomena. OSA, 2014. http://dx.doi.org/10.1364/up.2014.07.mon.p1.25.

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Reports on the topic "Pyrazine"

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Manson, J. L., D. Y. Villa, W. J. A. Blackmore, J. Brambleby, P. A. Goddard, and John Singleton. Low-T magnetometry study of S = 1 Q2D [Ni(pyz)2(H2O)2](BF4)2 (pyz = pyrazine). Office of Scientific and Technical Information (OSTI), 2017. http://dx.doi.org/10.2172/1343727.

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Habben, C., L. Komorowski, W. Maringgele, A. Meller, and K. Niedenzu. Reactions of Some Boron Heterocycles with Pyrazole. Defense Technical Information Center, 1989. http://dx.doi.org/10.21236/ada205979.

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Schmidt, R. D., G. S. Lee, P. F. Pagoria, A. R. Mitchell, and R. Gilardi. Synthesis and Properties of a New Explosive, 4-Amino-3,5-Dinitro-lH-Pyrazole (LLM-116). Office of Scientific and Technical Information (OSTI), 2001. http://dx.doi.org/10.2172/15005359.

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ธรรมเจริญ, สัมพันธ์, та ปรมัตถ์ กิจจานุกิจวัฒนา. กลไกการกระตุ้น ERα โดย PPT ต่อพฤติกรรมการกินอาหารและระดับคอติโค โทรปิน รีลิสซิ่งฮอร์โมนในสมองของหนูแรทเพศเมียที่ถูกตัดรังไข่ : รายงานวิจัย. คณะสัตวแพทยศาสตร์ จุฬาลงกรณ์มหาวิทยาลัย, 2014. https://doi.org/10.58837/chula.res.2014.71.

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โพรพิลไพราโซลไตรออย (Propyl-pyrazole-triol, PPT) ยับยั้งการกินอาหารอย่างรวดเร็วโดยการกระตุ้นตัวรับฮอร์โมนเอสโตรเจนชนิดแอลฟ่า (estrogen receptor alpha, ERα) ภายในสมอง กลุ่มผู้วิจัยได้เคยรายงานเกี่ยวกับผลการยับยั้งการกินอาหารที่รวดเร็วซึ่งอาจเกี่ยวข้องกับการกระตุ้นเซลล์ประสาทที่สามารถสร้าง คอร์ติโคโทรปิน รีลิ่สซิ่ง ฮอร์โมน (Corticotropin releasing hormone, CRH) ที่สมองส่วนพาราเวนตริคูล่านิวเคลียสของไฮโปทาลามัส (paraventricular nucleus of hypothalamus, PVN) โครงการวิจัยฉบับนี้ดำเนินการเพื่อศึกษาความเชื่อมโยงของ CRH ซึ่งเป็นสารสื่อประสาท (neuromediator) และฤทธิ์ยับยั้งการกินอาหารของ PPT ในการทดลอง
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