Academic literature on the topic 'Pyrazolo[3'

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Journal articles on the topic "Pyrazolo[3"

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Abaszadeh, Mehdi, Hassan Sheibani, and Kazem Saidi. "The Condensation of (Chlorocarbonyl)phenyl Ketene with Bisnucleophiles. Synthesis of 4-Hydroxy-5-phenylpyro-[2,3-c]pyrazol-6-ones and Formation of Pyrazolo[1,2-a]pyrazole-triones by Hydrogen Exchange in Unstable Mesoionic Compounds." Australian Journal of Chemistry 63, no. 1 (2010): 92. http://dx.doi.org/10.1071/ch09344.

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The addition of (chlorocarbonyl)phenyl ketene 2 to 5-alkylpyrazol-3(4H)-ones 1 led to the formation of 3-hydroxypyrazolo[1,2-a]pyrazole-dione/pyrazolo[1,2-a]pyrazole-trione derivatives 3. This is ascribed to hydrogen exchange in initially formed unstable, mesoionic pyrazolo[1,2-a]pyrazol-4-ium-5-olates. In contrast, condensation of the same ketene with 3-alkyl-1-phenyl-2-pyrazolin-5-ones 4 afforded 4-hydroxy-3-alkyl-1,5-diphenylpyrano[2,3-c]pyrazol-6-one derivatives 5. The latter reaction provides a new and rapid route to 4-hydroxy-2-pyrones fused to pyrazole rings, in good to excellent yields
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M., K. A. IBRAHIM, H. H. ELGHANDOUR A., S.M. ABDBL-SAYED G., and S.M. ABDEL FATTAH A. "Synthesis of Pyrazoles and Fused Pyrazoles. Novel Synthesis of Pyrano[2,3-c]pyrazole, Thieno[2,3-c]pyrazole and Pyrazolo[3,4-b ]pyridine Derivatives." Journal of Indian Chemical Society Vol. 74, Mar 1997 (1997): 206–8. https://doi.org/10.5281/zenodo.5885902.

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Department of Chemistry, Faculty of Science, Cairo University, Giza, A. R. Egypt <em>Manuscript received 17 November 1994, revised 26 July 1995, accepted 28 September 1995</em> 3-Metbyl-1-thiocarbamoylpyrazoi-5-one (1) reacted with <em>p</em>-metbylpbenscyl bromide to give 3-metbyl-1(4-tbiazol-2-yl)pyrazol-5-one (2). Compounds 1 and 2 were reacted with&nbsp;reagents such as &alpha;-cyanocinnamo. benzaldehyde, elemental suJphurlmalononltrlle, benzenediazomum chloride, pyrazol-5-yl-diazonium chloride malononitriie, and ethyl acetoacetate to afford pyrano[2,3-<em>c</em>]pyrazoles (4, 6)&nbsp;Pyra
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Deeb, Ali, Medhat El-Mobayed, Abdel Naby Essawy, Adel Abd El-Hamid, and Atef Mohamid Abd El-Hamid. "Heterocyclic synthesis from 3-amino-4-cyanopyrazole." Collection of Czechoslovak Chemical Communications 55, no. 3 (1990): 728–33. http://dx.doi.org/10.1135/cccc19900728.

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3-Amino-4-cyanopyrazole I reacts with hydroxylamine and with hydrazine to yield 1H,6H-3-aminopyrazolo[3,4-c]pyrazole (III and IV). Diazotized IV couples with 2-naphthol to give the arylazo derivative VI which cyclizes to 9H-naphthol[2,1-e]pyrazolo[3',4':3,4]pyrazolo[5,1-c]-[1,2,4]triazine VII by means of acetic acid. The pyrazol-5-ylthiourea obtained from I and phenyl isothiocyanate undergoes base-catalyzed cyclization to give pyrazolo[3,4-d]pyrimidinethione derivative IX. Compound I reacts with cyclohexane in the presence of zinc chloride to give the tetrahydropyrazolo[3,4-b]quinoline derivat
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Edrees, Mastoura M. "Synthesis of 4-hydrazinopyrazolo[3,4-d]pyrimidines and their Reactions with Carbonyl Compounds." Journal of Chemical Research 37, no. 1 (2013): 6–10. http://dx.doi.org/10.3184/174751912x13543818811749.

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Synthesis of a new 4-hydrazinopyrazolo[3,4- d]pyrimidine was achieved via heating (4,6-dithioxo-1 H-pyrazolo[3,4- d] pyrimidin-3-yl)acetonitrile with hydrazine hydrate. Reactions of the latter product with thiophene-2-carbaldehyde and ethyl hydrazonoacetoacetate analogues afforded the corresponding hydrazone and pyrazole derivatives, respectively. Similarly, condensation of 2-[6-(benzylsulfanyl)-4-hydrazino-1 H-pyrazolo[3,4- d]pyrimidin-3-yl]acetonitrile with thiophene-2-carbaldehyde and ethyl hydrazonoacetoacetate analogues gave the respective hydrazone and pyrazolone derivatives. Alkylation
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I.H. El-Qaliei, Mohamed, Sayed A.S. Mousa, Esam A. Ishak, Hamdi M.D. Nasr, Modather F Hussein, and Abdallah M.A. Hassane. "Synthesis, characterization, antimicrobial, antioxidant activities, and in silico study of new azo disperse dyes containing pyrazole and pyrazolo[1,5-a]pyrimidine rings." Bulletin of the Chemical Society of Ethiopia 39, no. 7 (2025): 1411–24. https://doi.org/10.4314/bcse.v39i7.13.

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New N,N-dimethyl-N'-(5-oxo-4-(aryldiazenyl)-2,5-dihydro-1H-pyrazol-3-yl)formimidamide 5a-c are formed by reaction of 5-amino-1H-pyrazol-3(2H)-one derivatives 4a-c with N,N-dimethylformamide dimethyl acetal (DMF-DMA). Compounds 5a-c serve as excellent precursors for the synthesis of new disazo pyrazole disperse dyes, When refluxed with hydrazine hydrate or active methylene reagents 8a,b, leading to N''-(3-hydroxy-4-(arylaza)-1H-pyrazol-5-yl)formimidohydrazide 7a-c or pyrazolo[1,5-a]. pyrimidines 11a–e. In vitro studies were carried out to evaluate antioxidant properties of the produced compound
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M., K. A. IBRAHIM, H. H. ELGHANDOUR A., ABOU-HADEED K., and S. ABDELHAFIZ I. "Utility of Hydrazidoyl Chlorides : Synthesis of New Pyrazoles, Pyrazolo[ 3,4-d]pyridazines, Pyrazolo[4,5-b]pyridines and Pyrazolo[ 4,5-d]pyrimidine Derivatives." Journal of Indian Chemical Society Vol. 69, Jul 1992 (1992): 378–80. https://doi.org/10.5281/zenodo.6004337.

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Chemistry Department, Faculty of Science, Cairo University, Giza, Egypt Chemistry Department, Faculty of Science. Suez-Canal University, Ismalia, Egypt <em>Manuscript received 28 October 1991 revised 26 May 1992, accepted 3 June 1992</em> Hydrazidoyl chlorides (1) were reacted with a variety of active methylene compounds and arylidemnialononitriles .1 medium, to produce polyfunctionally substituted pyrazole derivatives (2-6 and 10). The pyrazoles (2, 3, 6 and 10) were converted into the corresponding pyrazolo[3, 4-<em>d</em>]pyridazine derivatives (7 - 9 and 14), respectively. The aminopyraiol
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Elnagdi, Mohamed Hilmy, Ahmed Hafez Hussien Elghandour, Kamal Usef Sadek, and Mahmoud Mohamed Mahfouz Ramiz. "Studies on Condensed Pyrazoles. A New Route for Synthesis of Pyrazolo[4,3-c]pyrazoles." Zeitschrift für Naturforschung B 44, no. 8 (1989): 951–54. http://dx.doi.org/10.1515/znb-1989-0816.

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A novel synthesis of pyrazolo[4,3-c]pyrazoles via 1,5-dipolar cyclization of products of coupling of 2,3-dimethyl-1-phenyl-5-oxo-3-pyrazolin-4-diazonium chloride with active methylene reagents is reported.
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Lindsay-Scott, Peter J., and Eloise Rivlin-Derrick. "Regiocontrolled Synthesis of 6,7-Dihydro-4H-pyrazolo[5,1-c][1,4]oxazines." Synthesis 52, no. 01 (2019): 105–18. http://dx.doi.org/10.1055/s-0037-1610734.

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Synthetic access to 6,7-dihydro-4H-pyrazolo[5,1-c][1,4]oxazines has been achieved in 3–4 steps from commercially available pyrazoles. Optimization of a protected hydroxyethyl group on N1 enabled the regiocontrolled construction of pyrazole-5-aldehydes in high yields; subsequent deprotection and reduction generated fused heterocyclic scaffolds bearing multiple substitution patterns. Moreover, the intermediate pyrazole lactols were shown to be versatile synthetic building blocks.
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Abdelhamid, Abdou O., Zeineb H. Ismail, and Anhar Abdel-Aziem. "Reactions with Hydrazonoyl Halides 601: Synthesis of Thieno[2′,3′:4,5] Pyrimidino[1,2-b][1,2,4,5]tetrazines, [1]benzothieno[2′,3′:4,5]pyrimidino [1,2-b][1,2,4,5]tetrazines, Pyrazolo[3′,4′:4,5]pyrimidino[1,2-b] [1,2,4,5]tetrazines and Pyrazolo[3,4-d]pyridazines." Journal of Chemical Research 2007, no. 10 (2007): 609–16. http://dx.doi.org/10.3184/030823407x256118.

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Thieno[2′,3′:4,5]pyrimidino[1,2- b][1,2,4,5]tetrazine, [1]benzothieno-[2′,3′:4,5]pyrimidino[1,2- b][1,2,4,5]tetrazine, pyrazolo [3′,4′:4,5]pyrimidino[1,2- b][1,2,4,5]tetrazine, triazolo[4,3- a]pyrimidin-5(1 H)-one, 1-{[2-(1-benzofuran-2-yl)-5-phenyl-4,5-dihydro-1 H-pyrazol-1-yl]-4-substituted-1,3-thiazol-5-yl}-2-phenyldiazene, 3-acyl-4-(1-benzofuran-2-ylcarbonyl) pyrazole and pyrazolo[3,4- d]pyridazine derivatives could be obtained via reactions of hydrazonoyl halides with the appropriate pyrimidine-2-thione, 3-amino-5,6-dimethyl-2-sulfanylthieno[2,3- d]pyrimidin-4(3 H)-one, 5-amino-6-mercapto
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M., K. A. IBRAHIM, M. EL-REEDY A., S. EL-GHARIE M., and M. FARAG A. "Activated Nitrile in Heterocyclic Synthesis. A Novel Synthesis of Pyrazolo[3,4-b]pyridine, Pyrrolo[2, 3 -c ]pyrazole, Pyrano[2,-3c ]pyrazole and Pyrrolo[3,4-c ]pyrazole." Journal of Indian Chemical Society Vol. 64, Jun 1987 (1987): 345–47. https://doi.org/10.5281/zenodo.6237953.

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Chemistry Department, Faculty of Science, Cairo University, Giza, A. R. Egypt <em>Manuscript received 14 Match 1986, revised 4 November 1986, accepted 22 April 1987</em> The hydrazidoyl halides (2a &mdash; c) react with 2- amino-l,1,3-tricyano-1-propene (1a), diethyl 3-amino-2-cyano-2-pentene-1,5-dicarboxylate (1b), 3-iminobutaronitrile (1c), succinonitrile, 1,3 dicyano-2-iminopropane and 1,3-dicyanoacetone in sodium ethoxide solution to give the corresponding pyrazolo[3,4-<em>b</em>]pyridine (6), pyrano[2,3-<em>c</em>]pyrazole (7), pyrazole (10), pyrrolo[2,3-<em>c</em>]pyrazole (11), pyrazolo
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Dissertations / Theses on the topic "Pyrazolo[3"

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Bratenko, M. K. "Modern organic synthesis of pyrazolo[3,4-e][1,2,3]triazolo[1,5-a]diazepine-3-carboxamides." Thesis, БДМУ, 2020. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/18354.

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Do, Khoa Quang. "Design, Synthesis and Binding Studies of Trisubstitutedpyrazolo[3,4-d]pyrimidines." Thesis, Griffith University, 2006. http://hdl.handle.net/10072/367533.

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Pyrazolo[3,4-d]pyrimidines were known as adenosine antagonists at the rat A1 and A2A adenosine receptors based on our previous studies. In this study, 245 pyrazolo[3,4-d]pyrimidines derivatives with various benzyl substitutents at N-1 and various hydrophobic side chains at C-4 and C-6 were synthesized and screened at the human A1, A2A and A3 adenosine receptors. 14 out of 245 compounds were resynthesized and purified to determine the Ki values of these compounds at the human A1 adenosine receptor. Chapter 1 of the thesis is a literature review of adenosine research. It describes the physiology
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Laube, Markus. "Synthese von Cyclooxygenase-2-Inhibitoren als Grundlage für die funktionelle Charakterisierung der COX-2-Expression mittels PET." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-160091.

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Eine erhöhte COX-2-Expression wird bei Krankheiten wie rheumatoider Arthritis aber auch Parkinson, Alzheimer und Krebs beobachtet. Die nichtinvasive Visualisierung und Quantifizierung der COX 2-Expression in vivo mittels Positronen-Emissions-Tomographie (PET) könnte wertvolle Beiträge zur Diagnose dieser Krankheiten liefern. Zur Nutzung der PET-Technik werden geeignete COX-2-adressierende Radiotracer benötigt, deren Entwicklung auch die Identifizierung neuer, der Radiomarkierung zugänglicher COX-2-Inhibitoren als Leitstrukturen voraussetzt. Ziel dieser Arbeit war die Synthese von selektiven,
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Motson, Graham Robert. "Coordination chemistry of 3-(2'-pyridyl) pyrazole derivative ligands." Thesis, University of Bristol, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.391153.

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Desalegn, Nebiyou. "Kinetic Studies Of The Thermolysis Of 3-Halogenated-4,5-Dihydro-3h-Pyrazoles." Digital Archive @ GSU, 2005. http://digitalarchive.gsu.edu/chemistry_theses/1.

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3-Chloro-4,4,5-trimethyl-3,5-diphenyl-4,5-dihydro-3H-pyrazole (3b) and 3-bromo-4,4,5-trimethyl-3,5-diphenyl-4,5-dihydro-3H-pyrazole (3c) were prepared for the thermolysis project. The thermal decompositions of 3b and 3c were monitored using 1H NMR spectroscopy. Plots of ln (% starting material) vs. time (sec) were linear for at least two half lives and the first order rate constants were determined over at least a 30o temperature range. The relative reactivity was found to be 3c > 3b. The activation parameters determined for the thermal decomposition of the pyrazoline at 150oC were found to be
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Davies, Emyr D. "Novel bis (pyrazol-3-yl) ligands : their synthesis and coordination chemistry." Thesis, Cardiff University, 2007. http://orca.cf.ac.uk/54683/.

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This thesis describes studies into the development of new bis(pyrazol-3-yl) ligands including our studies into their coordination chemistry. Chapter 1 is a brief introduction to chelating ligands based on heterocycles and outlines specifically looks at poly(pyrazole-l-yl) ligands as well as the few bis(pyrazole-3-yl) ligands publishes to date. Chapter 2 looks at the traditional synthetic routes to bis(pyrazol-3-yl) ligands and describes how we have manipulated these techniques to synthesise some novel ligands of our own. Chapter 3 includes a study of the transition metal coordination chemistry
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Panasenko, N. V., and М. K. Bratenko. "Synthesis of 3-(3-aryl-1-phenyl-1H-4-pyrazolil)-chromen-2-ones." Thesis, БДМУ, 2017. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/16864.

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Barus, M. M. "А new approach to the preparation of 4-difluoromethyl-1Н-pyrazole-3-carboxylic acids". Thesis, БДМУ, 2022. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/19532.

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Oleksik, Laurence. "Methodology for the synthesis of 4 or 5-substituted-3-perfluoroalkyl pyrazoles." Thesis, University of Leicester, 2004. http://hdl.handle.net/2381/30087.

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Initially the perfluoroacylation of a range of commercially available vinyl ethers and conversion of the resulting perfluoroacylated enol ethers to 1-H-pyrazoles via reaction with hydrazine is reported. The selective synthesis of a range of alpha-aryl vinyl ethers using Heck chemistry is then reported. Subsequent perfluoroacylations of the vinyl ethers followed by reaction of the resulting perfluoroacyl enol ethers with hydrazine affords a range of 5-aryl-3-perfluoroalkyl pyrazoles in good yields.;Alternative methodology for the synthesis of 5-aryl-3-perfluoroalkyl pyrazoles is then described
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Nadir, Saïd. "Complexes de l'acide 3, 5-pyrazole dicarboxylique : synthèses, études structurales, utilisation pour la préparation de céramiques conductrices." Lille 1, 1996. https://pepite-depot.univ-lille.fr/LIBRE/Th_Num/1996/50376-1996-182.pdf.

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La synthese de ceramiques oxydes conductrices, par reaction a l'etat solide, necessite des traitements a haute temperature. Une autre methode est d'utiliser des composes de coordination precurseurs pour la preparation de materiaux oxydes hautement disperses. Nous avons utilise l'acide 3,5-pyrazole dicarboxylique (dcph#3) qui se decompose a 300c ; ce diacide est potentiellement tetrachelatant. Nous avons obtenu des complexes stables avec une grande variete d'elements (cu, bi, vo, ba, pb, ni, co) ; ceux ci ont ete caracterises par a. T. G et par diffraction x a haute temperature. La structure cr
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Books on the topic "Pyrazolo[3"

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Heidelberg, Universität, ed. Kupplung von Azulenen mit 3-Diazo-1H-pyrazolen zu 3-(1-Azulenylazo)-1H-pyrazolen und deren Reaktionen zu pyrazolo-kondensierten Azulensystemen. 1991.

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Künkemeier-Schröder, Birgit. Heterocyclische mesomere Betaine als Strukturelemente für neuartige flüssigkristalline Verbindungen: Synthese monomerer und dimerer 1-Oxo-1H-pyrazolo[1,2-a]pyrazol-4-ium-3-olate. 1992.

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Heidelberg, Universität, ed. Synthese, Photolyse und Thermolyse von 2,3,6,7-tetrasubstituierten 3H-pyrazolo[1,5-B]-1,2,4-triazolen zu 3-(2H-Azirin-2-yl)-1H-1,2,4-triazolen bzw. 6H-pyrazolo[1,5-A]-1,3,5-benzotriazepinen. Thermische Isomerisierung von 3-(2-Phenyl-3-methyl-2H-azirin-2-yl)-1H-1,2,4-triazolen zu 2-Methyl-3-triazol-3-ly-indolen. 1991.

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Dörner, Manfred. Synthese von in 3-Stellung H-substituierten Pyrazolo-[5,1-d]-1,2,3,5-tetrazin-4(3H)-onen sowie deren Glycosylierung zu Nucleosiden. 1986.

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Drixler, Willi. Untersuchungen zur Bildung von N,1,2-Tris-(toluol-4-sulfonyl)-3-pyrazolidinimin aus 3-Amino-1-(toluol-4-sulfonyl)-2-pyrazolin: Synthese von 1-Arylsulfonyl-3-arylsulfonylamino-2-pyrazolinen. 1986.

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Book chapters on the topic "Pyrazolo[3"

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Reger, Daniel L., James E. Collins, Donald L. Jameson, Ronald K. Castellano, Allan J. Canty, and Hong Jin. "Tris [N -(3-tert -Butyl) Pyrazolyl] methane." In Inorganic Syntheses. John Wiley & Sons, Inc., 2007. http://dx.doi.org/10.1002/9780470132630.ch9.

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Hamper, Bruce C., Kindrick L. Leschinsky, Deborah A. Mischke, and S. Douglas Prosch. "Chiral 3-Aryl-4-halo-5-(trifluoromethyl)pyrazoles." In ACS Symposium Series. American Chemical Society, 1999. http://dx.doi.org/10.1021/bk-2000-0746.ch019.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of dimeric cobalt(II) complex of 3, 5-dimethyl-pyrazole." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-662-45972-0_493.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of trimetallic cobalt(II) complex of 3, 5-dimethyl pyrazole." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-662-45972-0_492.

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Chandra, H., H. Fischer, F. A. Neugebauer, and M. C. R. Symons. "Radical Ions of Benzo[c]cinnolines and 2,3-Dihydro-1H-benzo[c]pyrazolo[1,2-a]cinnolines." In Organic Free Radicals. Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-73963-7_71.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of binuclear bis(acetylacetonato) chromium(III) complex bridged by pyrazole 3, 5-dicarboxylate." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-49202-4_508.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of copper(II) complex with 1, 3, 5-tris-(pyrazol-1-ylmethyl)benzene." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-53974-3_350.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of tetranuclear copper(II) acetato complex with pyrazol-3-yl-substituted nitronyl nitroxide." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 8. Springer Berlin Heidelberg, 2023. http://dx.doi.org/10.1007/978-3-662-66460-5_476.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of dinuclear copper(II) acetato complex with pyrazol-3-yl-substituted imino nitroxide." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 8. Springer Berlin Heidelberg, 2023. http://dx.doi.org/10.1007/978-3-662-66460-5_425.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of copper(II) chloro complex with (4,5-dimethyl-3-pyrazolyl)aldazine." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54237-8_142.

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Conference papers on the topic "Pyrazolo[3"

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Ledeneva, Irina, Vitaly Didenko, Victor Dotsenko, and Khidmet Shikhaliev. "Synthesis and reactions of pyrazolo[5,1-c][1,2,4]triazine-3-carbothioamides." In The 17th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2013. http://dx.doi.org/10.3390/ecsoc-17-a040.

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Stadlbaur, Wolfgang, Gerhard Hojas, and Werner Fiala. "Thermal Cyclization of 2-Hydrazonoacyl-3-oxo-heterocycles to Pyrazolo[4,3-c]fused Heterocycles." In The 2nd International Electronic Conference on Synthetic Organic Chemistry. MDPI, 1998. http://dx.doi.org/10.3390/ecsoc-2-01669.

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Galarraga, Elier, Neudo Urdaneta, and Julio Herrera. "In vitro Anti-leishmanial and Anti-trypanosomal Activity of Hydrazones, Pyrazoles, Pyrazolo[1,5-a]pyrimidines and Pyrazolo[3,4-b]pyridines Synthesized from 6-Substituted-3-formylchromones." In 2nd International Electronic Conference on Medicinal Chemistry. MDPI, 2016. http://dx.doi.org/10.3390/ecmc-2-a003.

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Popusoi, Ana, Nicanor Barba, and Aurelian Gulea. "Synthesis of 1,3-Phenyl(Pyridyl)propenones with thiosemicarbazidic groups." In Scientific seminar with international participation "New frontiers in natural product chemistry". Institute of Chemistry, Republic of Moldova, 2023. http://dx.doi.org/10.19261/nfnpc.2023.ab03.

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The bibliographic study of chalcones of the type 1,3-aryl(heteryl)propen-2-one with thiosemicarbazidic 4- and 1,4-disubstituted and thisemicarbazonic groups respectively gives us the information that they have a wide spectrum of biological activity, but methods of their synthesis are less described in the literature, and they became our object of study. 4,5-Dihydro-1-H-(pyrazol-3-yl)phenylhydrazinecarbothioamides 3a and 3b were obtained according to the following scheme:Reagents and reaction conditions: i, ii) 2-Py, 25oC – 24h, 90-95oC – 3h, 77-82%; iii) DMF, CH3COOH, 70-80oC, 2-3h, 60-63%. Fi
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Liu, Xiaobo, Shan Xu, and Yinhua Xiong. "Synthesis of 3-phenyl-1H-pyrazole Derivatives." In 2016 7th International Conference on Education, Management, Computer and Medicine (EMCM 2016). Atlantis Press, 2017. http://dx.doi.org/10.2991/emcm-16.2017.117.

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Kostić, Marijana S., Nikola D. Radnović, Ana Radović, et al. "Synthesis and physicochemical characterisation of the Ni(II) complex with 3- (4-chlorophenyl)-1H-pyrazole ligand." In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.527k.

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The coordination properties of 3-(4-chlorophenyl)-1H-pyrazole (HL) was investigated and its complex with Ni(II) ion was synthesized. The structure of the ligand was proven using SC-XRD, while both the ligand and the complex were characterized by spectroscopic, and thermogravimetric measurements. The purity and composition of the complex were confirmed by PXRD, elemental analysis, and conductometric measurements. Besides, the search for CSD was made to establish the frequency of different coordination modes of similar compounds. It was found that monodentate coordination of the neutral ligand m
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Jovanović Stević, Snežana, Snežana Radisavljević, Aleksandar Mijatović, Biljana Petrović, and Ana Kesić. "The influence of structural modification of Pd(II) pincer-type complexes on the kinetics of substitution reactions." In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.411js.

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This mini-review summarizes the kinetic data obtained for the substitution reactions of some palladium(II) complexes containing bis-pyrazolylpyridine derivatives as pincer-type ligands with biologically significant nitrogen- and sulfur-donor biomolecules as nucleophiles. Three structurally different palladium(II) complexes were selected: [Pd(L1)Cl]+(Pd1), [Pd(L2)Cl]+(Pd2) and [Pd(L3)Cl]+(Pd3) (where L1 = bis(2-(1H-pyrazol-1-yl)ethyl)amine, L2 = 2,6-bis(5-(tert-butyl)-1H-pyrazol-3-yl)pyridine, and L3 = 2,6-bis(5-(tert-butyl)-1-methyl-1H-pyrazol-3-yl)pyridine, while for the entering nucleophiles
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Mancini, Arianna, Anna Lucia Fallacara, Claudio Zamperini, et al. "Abstract 2201: Preclinical development of novel pyrazolo[3,4-d]pyrimidines structure-based TKIs for the treatment of glioblastoma." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-2201.

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Mancini, Arianna, Anna Lucia Fallacara, Claudio Zamperini, et al. "Abstract 2201: Preclinical development of novel pyrazolo[3,4-d]pyrimidines structure-based TKIs for the treatment of glioblastoma." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.am2019-2201.

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Prasad, T. N. Mahadeva, B. N. Lakshminarayana, Ebraheem Abdu Musad, et al. "Synthesis and X-ray Crystallographic Studies of ethyl 3-methyl5-(methylthio)-1H-pyrazole-4-carboxylate." In SOLID STATE PHYSICS, PROCEEDINGS OF THE 55TH DAE SOLID STATE PHYSICS SYMPOSIUM 2010. AIP, 2011. http://dx.doi.org/10.1063/1.3605798.

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Reports on the topic "Pyrazolo[3"

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ธรรมเจริญ, สัมพันธ์, та ปรมัตถ์ กิจจานุกิจวัฒนา. กลไกการกระตุ้น ERα โดย PPT ต่อพฤติกรรมการกินอาหารและระดับคอติโค โทรปิน รีลิสซิ่งฮอร์โมนในสมองของหนูแรทเพศเมียที่ถูกตัดรังไข่ : รายงานวิจัย. คณะสัตวแพทยศาสตร์ จุฬาลงกรณ์มหาวิทยาลัย, 2014. https://doi.org/10.58837/chula.res.2014.71.

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โพรพิลไพราโซลไตรออย (Propyl-pyrazole-triol, PPT) ยับยั้งการกินอาหารอย่างรวดเร็วโดยการกระตุ้นตัวรับฮอร์โมนเอสโตรเจนชนิดแอลฟ่า (estrogen receptor alpha, ERα) ภายในสมอง กลุ่มผู้วิจัยได้เคยรายงานเกี่ยวกับผลการยับยั้งการกินอาหารที่รวดเร็วซึ่งอาจเกี่ยวข้องกับการกระตุ้นเซลล์ประสาทที่สามารถสร้าง คอร์ติโคโทรปิน รีลิ่สซิ่ง ฮอร์โมน (Corticotropin releasing hormone, CRH) ที่สมองส่วนพาราเวนตริคูล่านิวเคลียสของไฮโปทาลามัส (paraventricular nucleus of hypothalamus, PVN) โครงการวิจัยฉบับนี้ดำเนินการเพื่อศึกษาความเชื่อมโยงของ CRH ซึ่งเป็นสารสื่อประสาท (neuromediator) และฤทธิ์ยับยั้งการกินอาหารของ PPT ในการทดลอง
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