Relevant bibliographies by topics / Pyridazinone Synthesis

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Pyridazinone Synthesis'

Author: Grafiati
Published: 4 June 2021
Last updated: 2 February 2022

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Journal articles on the topic "Pyridazinone Synthesis"

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Deeb, Ali, Besher Bayoumy, Fathy Yasine, and Rida Fikry. "Pyridazine Derivatives and Related Compounds, Part 4. Pyrrolo[2,3-c]pyridazines and Furo[2,3-c]pyndazines, Synthesis and Some Reactions." Zeitschrift für Naturforschung B 47, no. 3 (1992): 418–23. http://dx.doi.org/10.1515/znb-1992-0320.

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Ethyl 5-amino-3,4-diphenyl-7H-pyrrolo[2,3-c]pyridazine-6-carboxylate (1), ethyl 5-aminofuro[ 2,3-c]pyridazine-6-carboxylate (2) and 5-aminofuro[2,3-c]pyridazine-6-carboxamide (3), are obtained from 4-cyano-5,6-diphenyl-3(2H)-pyridazinone. 5-Acetamido and 5-chloroacetamido derivatives prepared from 1, undergo cyclization on heating to form 2-substituted pyridazino[4',3':4,5]pyrrolo[3,2-d]oxazin-4(5H)-one (5a, b). The reaction of 1 and 2 with hydrazine gave 6-carbohydrazide derivatives (7 a, b). Compound 3 undergoes condensation with acetyl chloride, chloroacetyl chloride, benzoyl chloride, form
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Rimaz, Mehdi, Jabbar Khalafy, and Peyman Najafi Moghadam. "A Regioselective One-Pot, Three Component Synthesis of 6-Aryl-4-cyano-3(2H)-pyridazinones in Water." Australian Journal of Chemistry 63, no. 9 (2010): 1396. http://dx.doi.org/10.1071/ch09602.

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A series of 4-cyano-3(2H)-pyridazinones bearing different aryl substituents in the 6-position of the pyridazinone ring was synthesized regioselectively using a novel efficient one-pot three component reaction of alkyl 2-cyanoacetates with arylglyoxals in the presence of hydrazine hydrate at room temperature in water.
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Hovakimyan, S. A., A. V. Babakhanyan, V. S. Voskanyan, V. E. Karapetian, G. A. Panosyan, and S. T. Kocharian. "Synthesis of Pyridazinone Derivatives." Chemistry of Heterocyclic Compounds 40, no. 8 (2004): 1047–51. http://dx.doi.org/10.1023/b:cohc.0000046696.37815.62.

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Tao, Jing. "Synthesis of Aldehyde Hydrazones Containing Pyridazinone." Advanced Materials Research 361-363 (October 2011): 2008–11. http://dx.doi.org/10.4028/www.scientific.net/amr.361-363.2008.

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The reaction of 1,4,5,6-tetrahydro-6-pyridazinone-3-carboxylic acid hydrazides (1) and 1,6-dihydro-6-pyridazinone-3-carboxylic acid hydrazides (2) with four kind of substituted 3-formyl chromones (3a-3d) and five kind of 1-phenyl-3-aryl-4-formylpyrazoles (3e-3i) afforded the new compounds aldehyde hydrazones (4a-4i) and (5a-5i). Their structures were established by IR, 1H NMR and elemental analysis.
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Asif, Mohammad. "Some Conventional and Convenient Process for Functionalization of 6-Phenyl-4,5-Dihydropyridazinone Compounds." Asian Journal of Chemistry and Pharmaceutical Sciences 1, no. 1 (2016): 41. http://dx.doi.org/10.18311/ajcps/2016/8375.

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The pyridazinone derivatives, particularly those bearing substituted different group or atom at a different position, have attracted considerable attention due to their characteristic pharmacological and other anticipated activities. These activities promoted the synthesis of a large number of substituted pyridazinone derivatives in order to explore the usefulness of this heterocyclic system. In the present review, various synthetic methods have been studied for the synthesis of substituted pyridazinone derivatives. The behaviour of the pyridazinone toward formaldehyde/piperidine, ethyl chloro
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Wasfy, Ashraf A. F., Mohamed M. H. Arief, Mahassen S. Amine, Shafey G. Donia та Aly A. Aly. "γ-Oxo Carboxylic Acids in Heterocyclic Synthesis, III. Synthesis of Biologically Active 4-Benzylamino-6-(5,5-dioxodibenzothiophen- 2-yl)-2,3,4,5-tetrahydropyridazin-3-ones". Zeitschrift für Naturforschung B 57, № 6 (2002): 668–76. http://dx.doi.org/10.1515/znb-2002-0613.

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α-Benzylamino-β-(5,5-dioxodibenzothiophen-2-carbonyl)propionic acid (1) has been synthesized by treating the corresponding β-aroylacrylic acid with benzylamine in dry benzene. On treatment with hydrazine hydrate the keto acid 1 furnishes the corresponding pyridazinone derivative 2. The behaviour of 2 towards carbon electrophiles, namely, ethyl chloroacetate, acrylonitrile, formaldehyde and secondary amines (under Mannich reaction conditions), aromatic aldehydes and carbon nucleophiles, namely, POCl3/PCl3 and P2S5 has been investigated. The 3-chloropyridazine derivative 13 reacts with hydrazine
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Samanta, Kartick Chandra, Mohd Asif, Pooja, Vikas Garg, Priyanka Sharma, and Ravinder Singh. "Synthesis of Different Substituted Pyridazinone Derivatives and Their Anticonvulsant Activity." E-Journal of Chemistry 8, no. 1 (2011): 245–51. http://dx.doi.org/10.1155/2011/873470.

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6-Phenyl(3᾽-imino-benzylidene)-2,3,4,5-tetrahydro pyridazin-3-one derivatives were synthesized from 6-(3᾽-aminophenyl)-2,3,4,5-tetrahydro pyridazin-3-one by reaction with different aldehydes. The respective pyridazinone was prepared by cyclization of appropriateβ-(aminophenyl) propionic acid with hydrazine hydrate. The pyridazinone derivatives were tested for anticonvulsant activity by MES (maximal electro shock) method and found that few of them have shown significant anticonvulsant activity.
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Ismail, Magda M. F., Dalia H. S. Soliman, Mona H. Abd Elmoniem, and Ghehad A. R. Abdel Jaleel. "Synthesis, Molecular Modeling of Novel Substituted Pyridazinones and their Vasorelaxant Activities." Medicinal Chemistry 17, no. 2 (2020): 171–86. http://dx.doi.org/10.2174/1573406416666200327191100.

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Background: Hypertension, one of the most common cardiovascular diseases that can cause coronary disease, stroke, myocardial infarction, and sudden death, it is the major contributor to cardiac failure as well as renal insufficiency. Objectives: As there are many cardio-active pyridazinone-base derivatives in clinical use, therefore, we aimed to synthesize a new series of pyridazin-3-ones and evaluate their vasorelaxant activity. Methods: A new series of synthesized compounds were carried out first by the synthesis of 6- flouroarylpyridazinones by cyclization of 3-(4-flourobenzoyl) propionic a
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TAKAYA, MASAHIRO. "Studies on Pyridazinone Derivatives. XI. Synthesis and Antifungal Activity of Amino Derivatives of Pyridazinone." YAKUGAKU ZASSHI 107, no. 10 (1987): 819–22. http://dx.doi.org/10.1248/yakushi1947.107.10_819.

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HUSAIN, ASIF, AFTAB AHMAD, ANIL BHANDARI, and VEERMA RAM. "SYNTHESIS AND ANTITUBERCULAR ACTIVITY OF PYRIDAZINONE DERIVATIVES." Journal of the Chilean Chemical Society 56, no. 3 (2011): 778–80. http://dx.doi.org/10.4067/s0717-97072011000300013.

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Dissertations / Theses on the topic "Pyridazinone Synthesis"

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Greenwood, Jeremy R. (Jeremy Robert) 1971. "Pyridazinediones and amino acid receptors theoretical studies, design, synthesis and evaluation of novel analogues." [Sydney : J. Greenwood], 1999. http://www.pharmacol.usyd.edu.au/thesis.

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Title from title screen. Interactive three dimensional molecular data and multiple colour images. Text presented in Hypertext Markup Language (.htm); images in standard formats (.jpg, .gif); molecules presented mostly as Cambridge Protein Data Bank format (.pdb); some molecules presented in alternative X.Mol cartesian co-ordinates format (.xyz); search facility in PERL script. Includes bibliographical references. Text, numeric and representational data System requirements: for text, any standard web browser on any platform, Netscape 2.x or higher, Internet Explorer 3.x or higher; for molecular
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Greenwood, Jeremy Robert. "Pyridazinediones and amino acid receptors: theoretical studies, design, synthesis, and evaluation of novel analogues." University of Sydney, Department of Pharmacology, 1999. http://hdl.handle.net/2123/394.

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http://www.pharmacol.usyd.edu.au/thesis This thesis is primarily concerned with a class of chemical compounds known as pyridazinediones, being 6-membered aromatic rings containing two adjacent nitrogen atoms (pyridazine), doubly substituted with oxygen. In particular, the work focuses on pyridazine-3,6-diones, derivatives of maleic hydrazide (1). Understanding of the chemistry of these compounds is extended, using theoretical and synthetic techniques. This thesis is also concerned with two very important classes of receptors which bind amino acids in the brain: firstly, the inhibitory GABA re
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Moniot, Aurélie. "Etude des effets anti-inflammatoires et anti-cancéreux de nouvelles molécules agrosourcées à motif pyridazinone Synthesis and biological evaluation of pyridazinone derivatives as potential antiinflammatory agents Osteoinductive Material to Fine-Tune Paracrine Crosstalk of Mesenchymal Stem Cells With Endothelial Cells and Osteoblasts." Thesis, Reims, 2020. http://www.theses.fr/2020REIMS022.

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L’ostéosarcome est un cancer primitif rare de l’os dont les approches thérapeutiques actuelles sont encore malheureusement insuffisantes pour espérer une totale guérison, et pour lequel la recherche de nouvelles molécules efficaces est constante. De plus, après exérèse de la tumeur, le défaut généré peut nécessiter de recourir à des matériaux aidant la reconstruction osseuse. Or le potentiel inflammatoire de ces matériaux est bien documenté. Les inhibiteurs de phosphodiestérase de type 4, parmi lesquels des molécules à motif pyridazinone, ont d’ores et déjà fait leurs preuves en tant qu’agents
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Byrichetti, Kiranmai. "Synthesis and Structure of a Substituted Pyridazine." TopSCHOLAR®, 2011. http://digitalcommons.wku.edu/theses/1080.

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Pyridazines are heterocyclic compounds with an N-N bond in their ring structure. Heterocyclic aromatic compounds are of great interest as a result of their novel properties and commercial applications. Our current research is focused on the potential role of pyridazines in next generation electronic devices that utilize organics as the semiconducting material. The synthesis of 5, 6-fused ring pyridazines beginning from fulvenes (Scheme 1) is described herein. These fused heterocycles will serve as synthetic models and building blocks for potential organic or organometallic conducting polymers.
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Greenwood, Jeremy R. "Pyridazinediones and amino acid receptors theoretical studies, design, synthesis and evaluation of novel analogues /." [Sydney : J. Greenwood], 1999. http://www.pharmacol.usyd.edu.au/thesis.

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Thesis (Ph. D.)--Dept. of Pharmacology, University of Sydney, 1999.<br>Title from title screen. Interactive three dimensional molecular data and multiple colour images. Text presented in Hypertext Markup Language (.htm); images in standard formats (.jpg, .gif); molecules presented mostly as Cambridge Protein Data Bank format (.pdb); some molecules presented in alternative X. Mol cartesian co-ordinates format (.xyz); search facility in PERL script. Includes bibliographical references. A printed form was produced with limited features as a Faculty requirement; may also be issued in CD-ROM.
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Moreau, Stéphane. "5-benzyl-6-methyl-pyridazines fonctionnalisees et systemes bicycliques condenses : syntheses, etudes pharmacologiques et modelisation moleculaire." Clermont-Ferrand 1, 1996. http://www.theses.fr/1996CLF1PP03.

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Mernari, Bouchaïb. "Complexes binucléaires de dérivés de la pyridazine ou du pyrazole synthèses, structures cristallines et interactions magnétiques /." Grenoble 2 : ANRT, 1987. http://catalogue.bnf.fr/ark:/12148/cb37607939k.

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Thomas, Jaron Michael. "On Metal synthesis of Some Substituted Rhenium and Manganese Complexes." TopSCHOLAR®, 2012. http://digitalcommons.wku.edu/theses/1225.

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Heterocyclic organic and organometallic compounds (i.e. polypyrrole), and their derivatives, have been of great interest for conductive polymers due to their novel properties and environmental stability as compared to their non-aromatic analogs (i.e. polyacetylene). Our current interest focus upon the potential role of metal ligand bound pyridazines as the next generation of electronic devices that utilize the metal ligands bound to organics as the semiconducting material. Pyridazine is a 6-membered aromatic ring with two adjacent nitrogen atoms. These are promising candidates for a variety of
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Scott, Joseph Brian. "Synthesis and Characterization of Some Rhenium Complexes." TopSCHOLAR®, 2009. http://digitalcommons.wku.edu/theses/114.

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Plastics or polymers are thought to behave oppositely from metals. Ideally, polymers behave as insulators while metals conduct electricity. Shirakawa and coworkers discovered conductive polymers in 1977.1 These conductor polymers have been extensively studied, discovering that charge transfer oxidative doping of polyacteylene could increase its conductivity by 12 orders of magnitude. Polyacetylene, although showing promise as an organic conductor, because it is highly air-sensitive and oxidizes when exposed to molecular oxygen, therefore making this an unattractive use for commercial produ
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Mykhaylychenko, Sergiy. "Study of perfluoroketene dithioacetals and N,S-acetals for the synthesis of fluorinated acyclic and heterocyclic compounds." Rouen, 2008. http://www.theses.fr/2008ROUES066.

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Les dithioacétals de perfluorocétènes sont des « synthons » simples et polyvalents pour la synthèse d'une large variété de composés fluorés acycliques et cycliques. Des transformations efficaces et directes des g-lactones a,b-insaturées en g-lactames et en pyridazin-3-ones substitués par un groupement 2,2,2-trifluoroéthyle ont été effectuées, à partir d'amines primaires et d'hydrazines variées et des dithioacétals de perfluorocétènes. La structure de tous les nouveaux composés a été assignée en utilisant les données de RMN (19F, 1H, 13C), d'IR et de MS et par diffraction des rayons X. Les réac
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Books on the topic "Pyridazinone Synthesis"

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Cinnolines and phthalazines: Supplement 2. Wiley, 2005.

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Book chapters on the topic "Pyridazinone Synthesis"

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Amoo, Victor E., Charles R. Harrison, George P. Lahm, et al. "Pyridazine Insecticides: Synthesis and Biological Activity." In ACS Symposium Series. American Chemical Society, 2001. http://dx.doi.org/10.1021/bk-2002-0800.ch015.

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Joule, J. A., K. Mills, and G. F. Smith. "The diazines: pyridazine, pyrimidine and pyrazine: reactions and synthesis." In Heterocyclic Chemistry. Springer US, 1995. http://dx.doi.org/10.1007/978-1-4899-3222-8_11.

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Shaner, Dale L., Laurine M. Speltz, and Stephen S. Szucs. "Synthesis and Herbicidal Activity of Pyridazines Based on 3-Chloro-4-methyl-6-[m-(trifluoromethyl)phenyl]pyridazine." In ACS Symposium Series. American Chemical Society, 1987. http://dx.doi.org/10.1021/bk-1987-0355.ch003.

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Lee, Seung Hee, Won Hee Han, Hyun Seo Shin, and Sang Jin Lee. "Synthesis of Phosphorescent Platinum Complexes with 3-Aryl Pyridazine as Prominent Emitting Materials in Organic Light-Emitting Device." In Key Engineering Materials. Trans Tech Publications Ltd., 2005. http://dx.doi.org/10.4028/0-87849-958-x.1006.

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Unger, Thomas A. "Pyridazines pyridazinones pyridazinediones." In Pesticide Synthesis Handbook. Elsevier, 1996. http://dx.doi.org/10.1016/b978-081551401-5.50406-8.

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Harris, P. A. "10.24.5 Product Subclass 5: Pyridazino[1,6-a]indoles and Related Benzo-Fused Ring Systems." In Science of Synthesis: Knowledge Updates 2021/3. Georg Thieme Verlag KG, 2021. http://dx.doi.org/10.1055/sos-sd-110-02114.

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AbstractThe synthesis of pyridazino[1,6-a]indoles, as well as the related indolo[1,2-b]cinnolines and indolo[2,1-a]phthalazines, are reviewed in this chapter. The most utilized methods to access pyridazino[1,6-a]indoles involve annulation of 1H-indol-1-amine derivatives.
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Wu, Xiao-Feng, and Zechao Wang. "Synthesis of Pyridazine." In Transition Metal Catalyzed Pyrimidine, Pyrazine, Pyridazine and Triazine Synthesis. Elsevier, 2017. http://dx.doi.org/10.1016/b978-0-12-809378-8.00004-3.

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Hilmy Elnagdi, Mohamed, Nouria A. Al-Awadi, and Ismail Abdelshafy Abdelhamid. "Chapter 1 Recent Developments in Pyridazine and Condensed Pyridazine Synthesis." In Advances in Heterocyclic Chemistry. Elsevier, 2009. http://dx.doi.org/10.1016/s0065-2725(08)00201-8.

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Wu, Xiao-Feng, and Zechao Wang. "Synthesis of Pyrimidine." In Transition Metal Catalyzed Pyrimidine, Pyrazine, Pyridazine and Triazine Synthesis. Elsevier, 2017. http://dx.doi.org/10.1016/b978-0-12-809378-8.00002-x.

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Wu, Xiao-Feng, and Zechao Wang. "Synthesis of Pyrazine." In Transition Metal Catalyzed Pyrimidine, Pyrazine, Pyridazine and Triazine Synthesis. Elsevier, 2017. http://dx.doi.org/10.1016/b978-0-12-809378-8.00003-1.

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Conference papers on the topic "Pyridazinone Synthesis"

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El Rayes, Samir M. "Convenient Synthesis and Antimicrobial Activity of Some Novel Pyridazinone Bearing Triazole Moieties." In The 14th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2010. http://dx.doi.org/10.3390/ecsoc-14-00493.

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Mátyus, Péter, Olivér Éliás, Lázló Károlyházy, Géza Stájer, Veronika Harmath, and Orsolya Barabás. "Ring Closure Reactions of 4-Chloro-5-hydroxyalkylamino-6-nitro-3(2H)- pyridazinones: Synthesis of Novel Pyridazino-Fused Ring Systems." In The 4th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2000. http://dx.doi.org/10.3390/ecsoc-4-01820.

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Salaheldin, Abdellatif, Lígia Rodrigues, and Ana Oliveira-Campos. "Heterocyclic Synthesis with Nitriles: Synthesis of Pyridazine and Pyridopyridazine Derivatives." In The 11th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2007. http://dx.doi.org/10.3390/ecsoc-11-01319.

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Schnell, Barbara, and Thomas Kappe. "Rearrangement of Heterocycles via-2-oxoketenes: Synthesis and Rearrangement Reactions of Cross-Conjugated Mesomeric Pyridazino[2,3-a]pyrimidine." In The 4th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2000. http://dx.doi.org/10.3390/ecsoc-4-01844.

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Hosmane, Ramachandra, та Huan-Ming Chen. "Synthesis of 1-(2'-Deoxy-γ-D-ribofuranosyl)-1H-imidazo[4,5-d]pyridazine-4,7(5 H,6H)-dion: a Potentially Beneficial Building Block for Antisense Applications". У The 4th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2000. http://dx.doi.org/10.3390/ecsoc-4-01926.

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Hosmane, Ramachandra, та Huan-Ming Chen. "Synthesis of 1-(2'-O-Methyl-γ -D-Ribofuranosyl)-1H-imidazo[4,5-d]pyridazine-4,7(5H,6H)-dion: an Attractive Building Block for Antisense and Triple-helical Applications". У The 4th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2000. http://dx.doi.org/10.3390/ecsoc-4-01925.

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Troitskaya-Markova, Nadezhda, Olga Vlasova та Oleg Rakitin. "4,5-DIOXO-4,5-DIHYDRO-4Λ4,5Λ4-BIS([1,2,5]OXADIAZOLO)[3,4-с:3',4'-e]PYRIDAZINE AS A SYNTHETIC EQUIVALENT OF 4,4'-DINITROSO-3,3'-BI(1,2,5-OXADIAZOLE)". У Chemistry of nitro compounds and related nitrogen-oxygen systems. LLC MAKS Press, 2019. http://dx.doi.org/10.29003/m779.aks-2019/305-307.

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