Academic literature on the topic 'Pyridine – Synthesis'

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Journal articles on the topic "Pyridine – Synthesis"

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Czarnocki, Zbigniew, and Piotr Pomarański. "Arylpyridines: A Review from Selective Synthesis to Atropisomerism." Synthesis 51, no. 03 (2018): 587–611. http://dx.doi.org/10.1055/s-0037-1611365.

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Multiply arylated heterocycles are interesting structures with highly useful functions and fascinating optoelectronic and biological properties. Pyridines are an important class of compounds, playing a role in various fields of chemistry. When the pyridine ring is connected to other aromatic systems, novel stereochemical outcomes may arise. This work summarizes different methodologies applied for the synthesis of substituted arylpyridine derivatives and summarizes stereochemical phenomena resulting from atropisomerism present in certain arylated pyridines.1 Introduction2 Arylpyridines Containi
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Bell, Zöe R., Jon A. McCleverty, and Michael D. Ward. "New Multidentate Pyrazolyl - Pyridine Ligands—Synthesis and Structures." Australian Journal of Chemistry 56, no. 7 (2003): 665. http://dx.doi.org/10.1071/ch02251.

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Five new multidentate ligands have been prepared containing N,N-bidentate pyrazolyl–pyridine units linked to a central aromatic spacer unit. The ligands 3,3′-bis(3-{pyridin-2-yl}-pyrazol-1-yl-methyl)-p-terphenyl (1), 4,4′-bis(3-{pyridin-2-yl}-pyrazol-1-yl)biphenyl (2), and 1,8-bis(3-{pyridin-2-yl}-pyrazol-1-yl-methyl)naphthalene (3) have two bidentate arms and are therefore potentially tetradentate; 2,6-bis(3-{pyridin-2-yl}-pyrazol-1-yl-methyl)pyridine (4) has two bidentate arms with an additional nitrogen-donor in the aromatic spacer unit (a pyridyl group) and is therefore potentially pentade
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Guoliang, G. U., and L. U. Ming. "Novel and Efficient Procedure for the Preparation of Two Pyridine Dicarboxylic Acid Derivatives." E-Journal of Chemistry 8, no. 1 (2011): 449–52. http://dx.doi.org/10.1155/2011/120730.

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New strategies for the synthesis of two pyridine dicarboxylic acid derivatives namely; 4-(2-(2,6-dicarboxypyridin-4-yl)vinyl)pyridine-2,6-dicarboxylic acid and 2,6-bis(2-(2,6–dicarboxy-pyridin-4-yl)vinyl)pyridine have been described. New oxidant used is a good example of green chemistry technology and the synthesis procedure harvest a high-purity product at a high yield.
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Dohe, Janis, and Thomas J. J. Müller. "Consecutive three- and four-component coupling-Bagley-Bohlmann-Rahtz syntheses of tri- and tetrasubstituted pyridines." Zeitschrift für Naturforschung B 71, no. 6 (2016): 705–18. http://dx.doi.org/10.1515/znb-2016-0046.

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AbstractThe concatenation of the modified Sonogashira alkynone synthesis and the Bagley-Bohlmann-Rahtz pyridine synthesis gives novel consecutive three- and four-component coupling-Bagley-Bohlmann-Rahtz (cBBR) syntheses of tri- and tetrasubstituted pyridines in a one-pot fashion. With these processes 15 differently substituted 3-ethoxycarbonyl 2-methylpyridines can be readily obtained in modest to moderate yields.
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Grinberga, S., A. Krauze, L. Krasnova, and G. Duburs. "Synthesis of 4-Benzo[1,3]Dioxol-5-Ylthieno-[2,3-b]Pyridines." Latvian Journal of Chemistry 51, no. 1-2 (2012): 143–48. http://dx.doi.org/10.2478/v10161-012-0002-2.

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Synthesis of 4-Benzo[1,3]Dioxol-5-Ylthieno-[2,3-b]Pyridines 4,7-Dihydrothieno[2,3-b]pyridine 4 and thieno[2,3-b]pyridine 6 were obtained by Thorpe-Ziegler cyclization. Mn(OAc)3/acetic acid system had been used for oxidation of 1,4-dihydropyridine 3 to pyridine derivative 5. 6-Carbamoylmethylsulfanyl-1,4-dihydropyridine 3 was prepared by al-kylation of piperidinium 1,4-dihydropyridine-2-thiolate 1 with iodoacet-amide.
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Miyakoshi, Takeru, and Hiroyuki Konno. "Improved synthesis of 2,4,6-trialkylpyridines from 1,5-diketoalkanes: the total synthesis of Anibamine." Organic & Biomolecular Chemistry 17, no. 11 (2019): 2896–905. http://dx.doi.org/10.1039/c8ob02723d.

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Gu, Guoliang, and Ming Lu. "A new facile synthesis of dimethyl 4-(2-(2,6-bis(methoxycarbonyl)pyridin-4-yl)vinyl) pyridine-2,6-dicarboxylate." Macedonian Journal of Chemistry and Chemical Engineering 29, no. 2 (2010): 165. http://dx.doi.org/10.20450/mjcce.2010.163.

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A new facile synthesis of pyridine dicarboxylic acid derivative, dimethyl 4-(2-(2,6-bis(methoxycarbonyl)pyridin-4-yl)vinyl)pyridine-2,6-dicarboxylate (DVDPA), from dimethyl 4-(chloromethyl)pyridine-2,6-dicarboxylate (CMDPA) in presence of nitrogen bases has been described. The influences of different base/CMDPA molar ratio and different nitrogen bases were also investigated. The result has shown that the yield could reach 81 % when triethylamine was used and the molar ratio of base/CMDPA was 2.4. The overall yield of title compound via the three-step synthesis starting from dimethyl 4-(hydroxy
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Gad-Elkareem, Mohamed A. M., Azza M. Abdel-Fattah, and Mohamed A. A. Elneairy. "Pyrazolo[3,4-b]pyridine in heterocyclic synthesis: synthesis of new pyrazolo[3,4-b]pyridines, imidazo[1',2':1,5]pyrazolo[3,4-b]pyridines, and pyrido[2',3':3,4]pyrazolo[1,5-a]pyrimidines." Canadian Journal of Chemistry 85, no. 9 (2007): 592–99. http://dx.doi.org/10.1139/v07-089.

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Pyrazolo[3,4-b]pyridine derivatives 7 and 9 were synthesized via the reaction of 3-amino-1H-pyrazolo-[3,4-b]pyridine derivative 2 with ω-bromoacetophenones. Reaction of 7 and 9 with Ac2O afforded the imidazo[1',2':1,5]py razolo[3,4-b]pyridine derivative 8 and pyrazolo[3,4-b]pyridine derivative 10, respectively. Reaction of 2 with chloroacetonitrile followed by DMF-DMA gave imidazo[1',2':1,5]pyrazolo[3,4-b]pyridines 4 and 5, respectively. Acetyl acetone and 1,1-dicyano-2,2-dimethylthioethene were reacted with 2 to afford the pyrido[2',3':3,4]pyrazolo-[1,5-a]-pyrimidines 11 and 14, respectively.
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Wei, Hongbo, та Yun Li. "Quick Access to Pyridines through 6π-3-Azatriene Electrocyclization: Concise Total Synthesis of Suaveoline Alkaloids". Synlett 30, № 14 (2019): 1615–20. http://dx.doi.org/10.1055/s-0037-1611811.

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Pyridine is a prevalent structural heterocyclic motifs in natural products, pharmaceuticals, and advanced materials. Several different methodologies have been developed for the synthesis of these kinds of molecules. However, a sustainable and efficient procedure for the synthesis of pyridines is still highly desirable. In this Synpacts article, we highlight our recent approach to the construction of highly substituted pyridines though a tandem condensation/alkyne isomerization/6π-3-azatriene electrocyclization sequence. The present protocol was used to synthesize a series of polysubstituted py
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Hafez, Hend N., and Abdel-Rahman B. A. El-Gazzar. "Synthesis of Novel Pyridine Bearing Biologically Active Imidiazolyl, Pyrazolyl, Oxa/thiadiazolyl and Urea Derivatives as Promising Anticancer Agents." Current Organic Synthesis 17, no. 1 (2020): 55–64. http://dx.doi.org/10.2174/1570179417666191223163225.

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Background: A novel series of pyridine containing 1,3,4-oxa/thiadiazol derivatives 4a,b, pyrazole derivatives 5-7, thiazole derivatives 9a,b and 17a-c, urea derivatives 12a-c, imidiazole derivative 16, imidazo[1,2-a]pyridine derivatives 18a, b, tetrazole 19, pyrane 20 and pyridine derivatives 21 has been synthesized. Objective: This research aims to synthesize 6-(Trifluoromethyl)-2-[3-(trifluoromethyl)phenyl] amino nicotinohydrazide 2 and 6-(trifluoromethyl)-2-[3-(trifluoromethyl)phenyl]amino pyridin-3-carboaldhyde 15 as key intermediate for the synthesis of novel pyridine derivatives bearing
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Dissertations / Theses on the topic "Pyridine – Synthesis"

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Hill, Matthew D. (Matthew Dennis). "Direct synthesis of pyridine and pyrimidine derivatives." Thesis, Massachusetts Institute of Technology, 2008. http://hdl.handle.net/1721.1/43776.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2008.<br>Vita.<br>Includes bibliographical references.<br>I. Synthesis of Substituted Pyridine Derivatives via the Ruthenium-Catalyzed Cycloisomerization of 3-Azadienynes. The two-step conversion of various N-vinyl and N-aryl amides to the corresponding substituted pyridines and quinolines, respectively, is described. The process involves the direct conversion of amides, including sensitive N-vinyl amides, to the corresponding trimethylsilyl alkynyl imines followed by a ruthenium-catalyzed protodesilylation and cyclois
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Otter, Carl A. "The synthesis and coordination chemistry of mixed donor pyridine/phenol and pyridine/sulfonamide ligands." Thesis, University of Bristol, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.246241.

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Knott, Jane Marie. "Studies on Pyridine n-oxides." Thesis, University of Oxford, 1995. http://ora.ox.ac.uk/objects/uuid:cc74d06b-9840-4695-9f47-961583da147c.

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The work described herein is directed towards the Claisen rearrangements and [3+2] cycloaddition reaction of pyridine N-oxide systems. The pyridine N-oxide molecule is a very versatile and useful synthetic intermediate for the construction of more complex pyridines. Chapter 1 contains a review of work carried out within the group towards Claisen rearrangement of benzene-type systems. The acid catalysed rearrangement of these systems affords a high degree of regioselectivity. A literature survey of the [3+2] cycloaddition reaction of both aliphatic nitrones and aromatic N-oxides with various di
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Isik, Murat. "Synthesis Of Various Camphor-based Chiral Pyridine Derivatives." Master's thesis, METU, 2005. http://etd.lib.metu.edu.tr/upload/12605824/index.pdf.

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Chiral aromatic nitrogen heterocycles are finding many applications in asymmetric organic synthesis, particularly as ligands in the preparation of chiral metal complexes. Since camphor-based chiral auxiliaries are known to be especially effective, a number of pyridines fused to the camphor skeleton have been reported. It is well known that nicotinic acid and its derivatives exhibiting qualitatively the biological activity of nicotinamide, which acts as an electron acceptor in many biological redox reactions. In connection to our works, we attempted to develop short and convenient way to prepar
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Blomberg, David. "Synthesis of β-turn and pyridine based peptidomimetics". Doctoral thesis, Umeå universitet, Kemi, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1104.

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Despite the unfavorable pharmacokinetic properties associated with peptides, they are still of great interest in drug development due to a multitude of interesting biological functions. The development of peptidomimetics strives to maintain or improve the biological activity of a peptide concurrently with removing the unwanted properties. This thesis describes two synthetic approaches to peptidomimetics with particular emphasis on secondary structure mimetics. First the design, synthesis and evaluation of two beta-turn mimetics incorporated in the endorphin Leu-enkephalin is presented. The bet
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Davis, Michael Leslie. "Design, synthesis and evaluation of pyridine-stretched oligonucleotides." Thesis, Aston University, 2005. http://publications.aston.ac.uk/12369/.

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Chan, Hoi-yiu, and 陳凱耀. "Design and synthesis of luminescent mono- and dinuclear platinum(II) alkynyl terpyridine complexes: fromphotophysics to aggregation and self-assembly." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2006. http://hub.hku.hk/bib/B36929232.

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Getmanenko, Yulia A. "Design, synthesis and mesomorphic behavior of 2,5-disubstituted pyridine liquid crystals." [Kent, Ohio] : Kent State University, 2007. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=kent1185592311.

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Thesis (Ph.D.)--Kent State University, 2007.<br>Title from PDF t.p. (viewed Nov. 21, 2007). Advisor: Robert J Twieg. Keywords: phenylpyridine LCs, thiophene-pyridine LCs, pyridinyl stannanes, selective Negishi coupling, liquid crystal semiconductors, smectic liquid crystals. Includes bibliographical references (p. 356-363).
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Alnomsy, Ayed Khalaf. "Synthesis and properties of pyridine containing drugs and heterocycles." Thesis, University of Sussex, 2017. http://sro.sussex.ac.uk/id/eprint/70414/.

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Chapter 1 provides an overview on the chemistry of pyridines and aminopyridines, their biological activities and their synthesis using Bohlmann-Rahtz, Hantzsch and Chichibabin methodology. It discusses the application of modern alternative reaction platforms, such as microwave-assisted synthesis and flow chemistry, of relevance to the synthesis and reactions of pyridine derivatrives. Chapter 2 discusses Lewis acid catalysis in the Bohlmann-Rahtz pyridine synthesis and describes new one-pot, two- and three-component methodologies that have been developed for the synthesis of natural products co
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Gunn, Mary Esther. "A modular catalytic approach towards pyridine and quinolone synthesis." Thesis, University of Leeds, 2013. http://etheses.whiterose.ac.uk/4959/.

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N-Containing heterocycles such as substituted pyridines and 2-quinolones are commonly found in drugs and agrochemicals; however, classical methods towards their synthesis often lead to limited substitution patterns. We recently described the first examples of the organocatalytic intramolecular aza-Wittig reaction in the synthesis of azoles and azines from isocyanates. The work described herein is divided into three chapters detailing attempts to expand the scope of the use of isocyanates in heterocycle synthesis. The first chapter describes the development of multicomponent synthesis of substi
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Books on the topic "Pyridine – Synthesis"

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Rhese, Joachim. Synthese von Konjugaten zwischen Tetrahydropterinen und 1,4-Dihydropyridinen. Hartung-Gorre, 1991.

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Stig, Lindholm. Design, synthesis, and antibacterial activity of some pyridylguanidines. Suomalainen Tiedeakatemia, 1990.

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Synthesis of imidazo[4,5-b]pyridines. Swedish University of Agricultural Sciences, Dept. of Chemistry, 1994.

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Shabib, Ihsan M. N. Synthetic and spectroscopic studies in the pyridine and pyridine 1-oxide fields. University of Birmingham, 1987.

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Banting, Lee. Synthesis and evaluation of perhydroimidazolo [3,4-a] pyridines as fungicides. Portsmouth Polytechnic, Dept. of Chemistry, 1985.

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Trethewey, Andrew Nicholas. Synthesis and evaluation of perhydro-oxazolo [3,4-a] pyridines as fungicides. Portsmouth Polytechnic, 1985.

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Cinnolines and phthalazines: Supplement 2. Wiley, 2005.

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Wu, Xiao-Feng. Transition Metal-Catalyzed Pyridine Synthesis: Transition Metal-Catalyzed Heterocycle Synthesis Series. Elsevier Science & Technology Books, 2016.

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Transition Metal-Catalyzed Pyridine Synthesis. Elsevier, 2016. http://dx.doi.org/10.1016/c2015-0-05506-x.

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Liu, Hshiou-ting. A new pyridine synthesis and studies directed toward the synthesis of a receptor to distinguish between enantiomers of chiral g□as□-amino acids. 1986.

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Book chapters on the topic "Pyridine – Synthesis"

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Li, Jie Jack. "Hantzsch pyridine synthesis." In Name Reactions. Springer Berlin Heidelberg, 2002. http://dx.doi.org/10.1007/978-3-662-04835-1_122.

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Li, Jie Jack. "Boger pyridine synthesis." In Name Reactions. Springer Berlin Heidelberg, 2002. http://dx.doi.org/10.1007/978-3-662-04835-1_32.

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Li, Jie Jack. "Chichibabin pyridine synthesis." In Name Reactions. Springer Berlin Heidelberg, 2002. http://dx.doi.org/10.1007/978-3-662-04835-1_55.

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Li, Jie Jack. "Kröhnke pyridine synthesis." In Name Reactions. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-01053-8_143.

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Li, Jie Jack. "Boger pyridine synthesis." In Name Reactions. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-01053-8_27.

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Li, Jie Jack. "Chichibabin pyridine synthesis." In Name Reactions. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-01053-8_51.

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Li, Jie Jack. "Kröhnke pyridine synthesis." In Name Reactions. Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-03979-4_152.

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Li, Jie Jack. "Boger pyridine synthesis." In Name Reactions. Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-03979-4_31.

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Li, Jie Jack. "Chichibabin pyridine synthesis." In Name Reactions. Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-03979-4_58.

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Li, Jie Jack. "Chichibabin pyridine synthesis." In Name Reactions. Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/978-3-662-05336-2_57.

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Conference papers on the topic "Pyridine – Synthesis"

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Pyrko, A. N., and M. V. Smolnik. "SYNTHESIS OF NEW POLYCYCLIC PYRIDINE DERIVATIVES." In SAKHAROV READINGS 2020: ENVIRONMENTAL PROBLEMS OF THE XXI CENTURY. Minsk, ICC of Minfin, 2020. http://dx.doi.org/10.46646/sakh-2020-2-158-161.

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Cañete, Álvaro, Christel Maldonado, and Ricardo A. Tapia. "Regiospecific synthesis of 3-bromo-2-(phenylsulfanyl)pyridine derivatives." In 14th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0141-1.

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Tadjarodi, Azadeh, and Neda Imani. "Solvent-free synthesis of Pyridine-2-aminium-6-methyl Pyridine-2,6-dicarboxylate under ball-milling conditions." In The 12th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2008. http://dx.doi.org/10.3390/ecsoc-12-01223.

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Salles*, Helena D. de, Tiago L. da Silva, Cátia S. Radatz, and Paulo H. Schneider. "Preliminary studies on Cu/SiO2 catalyzed imidazo[1,2-a]pyridine multicomponent synthesis." In 15th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-15bmos-bmos2013_201391521851.

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Fiedor, Pawel, Joanna Ortyl, and Mariusz Galek. "MICROWAVE-ASSISTED SYNTHESIS AND SPECTROSCOPIC PROPERTIES OF NOVEL PYRIDINE-BASED FLUORESCENT MOLECULAR PROBES." In Ampere 2019. Universitat Politècnica de València, 2019. http://dx.doi.org/10.4995/ampere2019.2019.9829.

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Fluorescent molecular probes become interesting analytical tools in determination and labeling of chemical compounds and physical properties such as viscosity and polarity. Currently known fluorescent molecular probes can selectively and regardless of the environment detect only few molecules, and applicability in determination of micro- viscosity and micro-polarity are limited to narrow range and specific condition, therefore design and synthesis of novel molecular probes with extended range of operation are highly needed [1]. Traditional synthesis of 2-amino-4,6-diphenyl-pyridine-3-carbonitr
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Zheng, Lianying, Ying Zhao, Ruifa Zong, et al. "Synthesis and FT-IR study of Ln-Glucose-Pyridine complexes." In The eleventh international conference on fourier transform spectroscopy. AIP, 1998. http://dx.doi.org/10.1063/1.55791.

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Castro, Kelly Leite dos Santos, Rodrigo Octavio Mendonça Alves de Souza, and Leandro Soter de Mariz e. Miranda. "Ionic liquids derived from pyridine and their application in Suzuki-Miyaura reaction under microwave irradiation." In 14th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0098-2.

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Duan, Yongli, Zhimin Li, Qidong Tang, Rui Li, and Shan Xu. "Synthesis of 4-Chloro-N, N-Dimethyl Pyridine Car Box Amide." In 2016 7th International Conference on Education, Management, Computer and Medicine (EMCM 2016). Atlantis Press, 2017. http://dx.doi.org/10.2991/emcm-16.2017.111.

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Liu, Y., X. H. Zhang, W. J. Ding, and X. X. Sun. "Synthesis of 4-Carbazole -7- Thiophen[1,2,5] Thiadiazolo [3,4-C]Pyridine." In The International Workshop on Materials, Chemistry and Engineering. SCITEPRESS - Science and Technology Publications, 2018. http://dx.doi.org/10.5220/0007435401220126.

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Sreenivasulu, T., G. Mallikarjuna Reddy, G. Sravya, A. Padmaja, and Grigory V. Zyryanov. "Synthesis, characterization and antimicrobial activity of pyridine linked hydrazinyl oxazoles/imidazoles." In PROCEEDINGS OF THE 3RD INTERNATIONAL CONFERENCE ON AUTOMOTIVE INNOVATION GREEN ENERGY VEHICLE: AIGEV 2018. Author(s), 2019. http://dx.doi.org/10.1063/1.5087387.

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Reports on the topic "Pyridine – Synthesis"

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Hellier, Paul C., Jerald S. Bradshaw, and Reed M. Izatt. Synthesis of Chiral Pyridine-Based Macrobicyclic Clefts. Defense Technical Information Center, 1996. http://dx.doi.org/10.21236/ada309257.

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