Relevant bibliographies by topics / Pyrimidinols

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Pyrimidinols'

Author: Grafiati
Published: 4 June 2021
Last updated: 2 February 2022

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Journal articles on the topic "Pyrimidinols"

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Valgimigli, Luca, Daniele Bartolomei, Riccardo Amorati, et al. "3-Pyridinols and 5-pyrimidinols: Tailor-made for use in synergistic radical-trapping co-antioxidant systems." Beilstein Journal of Organic Chemistry 9 (December 4, 2013): 2781–92. http://dx.doi.org/10.3762/bjoc.9.313.

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The incorporation of nitrogen atoms into the aromatic ring of phenolic compounds has enabled the development of some of the most potent radical-trapping antioxidants ever reported. These compounds, 3-pyridinols and 5-pyrimidinols, have stronger O–H bonds than equivalently substituted phenols, but possess similar reactivities toward autoxidation chain-carrying peroxyl radicals. These attributes suggest that 3-pyridinols and 5-pyrimidinols will be particularly effectiveco-antioxidants when used in combination with more common, but less reactive, phenolic antioxidants such as 2,6-di-tert-butyl-4-
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Wenska, Grazyna, Bohdan Skalski, and Zofia Gdaniec. "Transformation of 1-methyluracils and uridine to respective, 4-substituted pyrimdin-2(1H)-ones via pyridinium salts." Canadian Journal of Chemistry 70, no. 3 (1992): 856–62. http://dx.doi.org/10.1139/v92-113.

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1-Methyluracil and 1-methylthymine are converted into N-(1-methylpyrimidin-2-one-4-yl)- and N-(1-dimethylpyrimidin-2-one-4-yl)-pyridinium chlorides, respectively. The pyrimidinyl-pyridinium salts were then reacted with various nucleophiles under very mild conditions to give high yields of the desired 4-substituted pyrimidinones. In a similar manner 2′,3′,5′-tri-O-acetyluridine is efficiently converted into new 4-substituted pyrimidinone nucleosides.
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Adomėnienė, Ona, Povilas Adomėnas, Antanas Gleiznys, Aldona Beganskienė, Lidija Poloudina, and Yasuyuki Gotoh. "Mesomorphic Properties of New 5-Alkyl-2-Pyrimidinols Esters." Molecular Crystals and Liquid Crystals Science and Technology. Section A. Molecular Crystals and Liquid Crystals 364, no. 1 (2001): 739–43. http://dx.doi.org/10.1080/10587250108025043.

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Pratt, Derek A., Gino A. DiLabio, Giovanni Brigati, Gian Franco Pedulli, and Luca Valgimigli. "5-Pyrimidinols: Novel Chain-Breaking Antioxidants More Effective than Phenols." Journal of the American Chemical Society 123, no. 19 (2001): 4625–26. http://dx.doi.org/10.1021/ja005679l.

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Domínguez, Moisés, Matías Vidal, Macarena García-Arriagada, and Marcos Rezende. "Ultrasound-Promoted Synthesis of 4-Pyrimidinols and Their Tosyl Derivatives." Synthesis 48, no. 23 (2016): 4246–52. http://dx.doi.org/10.1055/s-0035-1562788.

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Wajon, J. F. M., та J. F. Arens. "The formation of pyrimidinols from α-acylbenzyl cyanides or α-acylphenylacetamides". Recueil des Travaux Chimiques des Pays-Bas 76, № 1 (2010): 79–91. http://dx.doi.org/10.1002/recl.19570760110.

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Nekkaa, Imane, Márta Palkó, István M. Mándity, and Ferenc Fülöp. "Continuous-flow retro-Diels–Alder reaction: an efficient method for the preparation of pyrimidinone derivatives." Beilstein Journal of Organic Chemistry 14 (February 1, 2018): 318–24. http://dx.doi.org/10.3762/bjoc.14.20.

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The syntheses of various pyrimidinones as potentially bioactive products by means of the highly controlled continuous-flow retro-Diels–Alder reaction of condensed pyrimidinone derivatives are presented. Noteworthy, the use of this approach allowed us to rapidly screen a selection of conditions and quickly confirm the viability of preparing the desired pyrimidinones in short reaction times. Yields typically higher than those published earlier using conventional batch or microwave processes were achieved.
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Latif, F. M. Abd El, A. S. Maghraby, M. A. Barsy, M. Z. A. Badr, and D. Dopp. "New Pyrazoline Derivatives." Collection of Czechoslovak Chemical Communications 59, no. 1 (1994): 247–52. http://dx.doi.org/10.1135/cccc19940247.

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The biological activity of azoles, pyrimidines as well as pyrazolines are of interest. Formation of pyrazolines and related compounds from hydrazine derivatives and α,β-unsaturated carbonyl compounds is very common. Pyrazoline fused with different heterocyclic nuclei at position 4 and 5 have been reported. Here we report the synthesis of some new monocyclic or fused azoles and pyrimidinones linked to C-4 or 5-chloro-3-methyl-1-phenylpyrazoline.
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Valgimigli, Luca, Giovanni Brigati, Gian Franco Pedulli, et al. "The Effect of Ring Nitrogen Atoms on the Homolytic Reactivity of Phenolic Compounds: Understanding the Radical-Scavenging Ability of 5-Pyrimidinols." Chemistry - A European Journal 9, no. 20 (2003): 4997–5010. http://dx.doi.org/10.1002/chem.200304960.

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Nielsen, P., and A. Bacher. "Biosynthesis of Riboflavin. A Simple Synthesis of the Substrate and Product of the Pyrimidine Deaminase and of Structural Analogs." Zeitschrift für Naturforschung B 43, no. 10 (1988): 1358–64. http://dx.doi.org/10.1515/znb-1988-1025.

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2-Amino-5-nitro-6-ribitylamino-4(3H)-pyrimidinone (7) was phosphorylated with chlorophosphoric acid yielding an isomer mixture containing about 63% of the 5´-phosphate 7a together with other monophosphates and bisphosphates of 7. Preparative HPLC afforded pure 7a. Catalytic hydrogenation of 7a yields the labile substrate of pyrimidine deaminase, 2,5-diamino-6-ribityl-amino-4(3H)-pyrimidinone 5´-phosphate (2a). The product of the enzyme, 5-amino-6-ribityl-amino-2,4(1H,3H)-pyrimidinedione 5´-phosphate (4a), can be obtained from 5-nitro-6-ribityl-amino-2,4(1H,3H)-pyrimidinedione (8) by an analogo
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Dissertations / Theses on the topic "Pyrimidinols"

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Čepulytė, Simona. "Pirimidinolių alkilintų darinių sintezė." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2005. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2005~D_20050613_183542-65729.

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In this work the alkylation of 2-ethylsulfanyl -5-methoxy-4(3H)-pyrimidinone with 4-substituted ω-bromoacetophenones, ethyl 2-bromoalkanoates and 1-bromomethyl-o-carborane was investigated. It was found that reaction of title compounds in the presence of potassium carbonate in boiling acetonitrile yielded O-alkylated derivatives with small amount of N3- and N1-alkylation products. The proportion of O- and N-alkylated products varied depending on the nature of substituent in the 4th position of benzene ring. Alkylation of title compound with ethyl bromoethanoate led to mixture of O-, N3- and N1
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Mélo, Sébastiao José de. "Synthèse, réactivité et propriétés pharmacologiques des fluoro-5 (3H) pyrimidinones-4." Université Joseph Fourier (Grenoble), 1989. http://www.theses.fr/1989GRE18003.

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Hou, Geneviève. "Synthèse de pyrido et de thiénopyrimidin-4(3H)-ones et de leurs produits de réduction : intérêt potentiel de ces composés dans le traitement de la thrombose." Bordeaux 2, 1997. http://www.theses.fr/1997BOR2E001.

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Collado, Ruiz Sandra. "Palladation et fonctionnalisation de pyrimidinones et d'imidazolones." Thesis, Normandie, 2018. http://www.theses.fr/2018NORMIR21/document.

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Depuis ces dix dernières années, notre laboratoire a développé une expertise dans le domaine de la fonctionnalisation de liaisons carbone-hydrogène (dite fonctionnalisation C-H) d’hétérocycles par catalyse aux métaux de transition. Le sujet de thèse s’inscrit dans un programme de recherche dirigé vers les hétérocycles pro-aromatiques à système N-acylamidine. Les travaux antérieurs ont porté sur les 4-alkyl et 4-arylidène imidazolones avec la production de nouvelles sondes GFP. Le présent travail de thèse vise à poursuivre le développement méthodologique en série pyrimidin-4-ones,encore très pe
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Griffin, Roger J. "Novel biological roles for pyrimidines." Thesis, Aston University, 1986. http://publications.aston.ac.uk/12540/.

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The development of classical and lipophilic inhibitors of dihydrofolate reductase (DHFR) as antitumour agents is reviewed and the advantages and problems associated with each class are discussed. The antitumour activity, pharmacokinetics and metabolism of m-azido-pyrimethamine (MZP), a novel lipophilic inhibitor, are considered and compared with metoprine, the prototype lipophilic antifolate. Evidence for a folate-independent target for lipophilic DHFR inhibitors is presented. Synthetic studies centred on three principal objectives. Firstly a series of structural analogues of MZP were prepared
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Malavolta, Juliana Limana. "Síntese de Pirimidinas derivadas de 7,7,7-trialo-4-metoxi-6-oxo-4- heptenoatos de metila e bi-heterociclos trifluormetilados." Universidade Federal de Santa Maria, 2012. http://repositorio.ufsm.br/handle/1/10501.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>An efficient method to obtain pyrimidinones and pyrimidines trialomethylated from the cyclocondensation reaction of compounds of methyl 7,7,7-trihalo-4-methoxy-6-oxoheptenoate with urea and differents amidines providing the series of compounds pyrimidines and pyrimidinones trifluoromethylated and trichloromerthylated is reported.Some compounds of the series were selected and brought to reaction with hydrazine monohydrate obtaining the series of new 6-(trifluoromethyl)pyrimidin-4-propanehydrazide, of which two were later brought to
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Lee, Jeong-Hwan. "Synthesis of pyrrolo[2,3-d]pyrimidines and pyrazino[2,3-d]pyrimidines and their biological activities." Thesis, University of Strathclyde, 2010. http://oleg.lib.strath.ac.uk:80/R/?func=dbin-jump-full&object_id=14350.

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Hannah, Duncan Robert. "The chemistry of imidazoles and pyrimidinones." Thesis, University of Nottingham, 1997. http://eprints.nottingham.ac.uk/12306/.

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The reactions of amino- and formylimidazoles, and aminopyrimidinones are described. Conditions were found for the successful condensation of 5(4)-aminoimidazole-4(5)-carboxamide with a number of substituted benzaldehydes, to provide a series of novel 5(4)-N-benzylideneaminoimidazole-4(5)-carboxamides. Reaction of a subset of the benzylidene derivatives with sodium hydride furnished novel imidazo[1,5-a]quinazoline-3-carbox-amides in good yields, via an intramolecular cyclisation. Attempted mixed acid nitration of imidazo[1,5-a]quinazoline-3-carboxamide led only to amide hydrolysis to provide th
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Langlet, Abraham. "Nitration of oxo-pyrimidines and oxo-imidazoles /." Stockholm, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-601.

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Parks, Emma Louise. "Polyfunctionalised pyrimidines and pyrazines from perhalogenated precursors." Thesis, Durham University, 2008. http://etheses.dur.ac.uk/2551/.

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Chapter 1 introduces the modem pharmaceutical industry in terms of the drug discovery process leading into a discussion of the relevance of heterocyclic compounds with particular focus on the synthesis of multifunctional pyrimidines and pyrazines. An introduction into organofluorine chemistry is included followed by a review of the literature on 5-chloro-trifluoropyrimidine, tetrafluoropyrimidine and tetrafluoropyrazine. Chapter 2 describes a study of the reactivity of 5-chlorotrifluoropyrimidine with mono- and difunctional-nucleophiles. This research demonstrates the former are not selective
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Books on the topic "Pyrimidinols"

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Brown, D. J. Pyrimidines. Wiley, 1993.

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2

The pyrimidines. Wiley, 1994.

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Delia, Thomas J. Miscellaneous fused pyrimidines. Wiley, 1992.

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Griffin, Roger John. Novel biological roles for pyrimidines. Aston University. Department of Pharmaceutical Sciences, 1986.

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5

Pfleiderer, Mathias. Synthese und Eigenschaften 6-substituierter Pyrido[2,3-d]pyrimidine. Hartung-Gorre, 1986.

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Omar, Abdirahman Hagi Hassan. Reactions of trihalomethyl derivatives of pyridines and pyrimidines with nucleophiles. University of Salford, 1986.

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7

I, Bruskov V., та Poltev V. I, ред. Novye pret͡s︡izionnye obʺemnye atomno-molekuli͡a︡rnye modeli. Nauch. t͡s︡entr biologicheskikh issledovaniĭ AN SSSR v Pushchine, 1985.

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International Symposium on Human Purine and Pyrimidine Metabolism (6th 1988 Hakone-machi, Japan). Purine and pyrimidine metabolism in man VI. Plenum Press, 1989.

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1926-, Nyhan William L., Thompson L. F. 1947-, Watts R. W. E, and Seegmiller J. E, eds. Purine and pyrimidine metabolism in man V. Plenum Press, 1986.

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International Symposium on Purine and Pyrimidine Metabolism in Man (7th 1991 Bournemouth, England). Purine and pyrimidine metabolism in man VII. Plenum Press, 1991.

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Book chapters on the topic "Pyrimidinols"

1

Dudaş, Nicoleta A., and Mihai V. Putz. "Pyrimidines." In New Frontiers in Nanochemistry. Apple Academic Press, 2020. http://dx.doi.org/10.1201/9780429022937-41.

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Mehlhorn, Heinz. "Pyrimidines." In Encyclopedia of Parasitology. Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-43978-4_2622.

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Brown, E. G. "Pyrimidines." In Ring Nitrogen and Key Biomolecules. Springer Netherlands, 1998. http://dx.doi.org/10.1007/978-94-011-4906-8_5.

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Mehlhorn, Heinz. "Pyrimidines." In Encyclopedia of Parasitology. Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-27769-6_2622-2.

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Li, Jie Jack, and Minmin Yang. "Pyrimidines." In Drug Discovery with Privileged Building Blocks. CRC Press, 2021. http://dx.doi.org/10.1201/9781003190806-24.

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Hirota, E., K. Kuchitsu, T. Steimle, J. Vogt, and N. Vogt. "86 C4H4N2O 4-Pyrimidinol." In Molecules Containing Three or Four Carbon Atoms and Molecules Containing Five or More Carbon Atoms. Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-41504-3_87.

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Unger, Leon. "Purines and Pyrimidines." In Oklahoma Notes. Springer US, 1987. http://dx.doi.org/10.1007/978-1-4684-0294-0_9.

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Unger, Leon. "Purines and Pyrimidines." In Oklahoma Notes. Springer US, 1992. http://dx.doi.org/10.1007/978-1-4684-0437-1_11.

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Jeffrey, George A., and Wolfram Saenger. "Purines and Pyrimidines." In Hydrogen Bonding in Biological Structures. Springer Berlin Heidelberg, 1994. http://dx.doi.org/10.1007/978-3-642-85135-3_15.

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Unger, Leon. "Purines and Pyrimidines." In Oklahoma Notes. Springer New York, 1995. http://dx.doi.org/10.1007/978-1-4612-4200-0_11.

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Conference papers on the topic "Pyrimidinols"

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Zhang, Hefeng, Xia Peng, Yinchun Ji, et al. "Abstract 3051: A potent pyrimidinone Axl inhibitor DW17401." In Proceedings: AACR Annual Meeting 2020; April 27-28, 2020 and June 22-24, 2020; Philadelphia, PA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.am2020-3051.

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Slivka, Mar V., M. M. Fizer, D. Zh Bereksazi, et al. "Preparation of Bioactive Fused Pyrimidines via Environmental Technologies." In 2019 International Council on Technologies of Environmental Protection (ICTEP). IEEE, 2019. http://dx.doi.org/10.1109/ictep48662.2019.8968984.

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Shutalev, Anatoly, and Anastasia Fesenko. "A Novel Ring Expansion of Pyrimidines to 1,2,4-Triazepines." In The 20th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2016. http://dx.doi.org/10.3390/ecsoc-20-a018.

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Mukhin, E., V. Fedotov, E. Ulomsky, and V. Rusinov. "NON-NATURAL NUCLEOSIDES BASED ON AZOLO[1,5-A]PYRIMIDINES." In Chemistry of nitro compounds and related nitrogen-oxygen systems. LLC MAKS Press, 2019. http://dx.doi.org/10.29003/m771.aks-2019/279-280.

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Koos, M., B. Steiner, and J. Gajdos. "Synthesis of Some Sulfur Bridged Pyrimidines, Pyrazoles and Imidazoles." In The 1st International Electronic Conference on Synthetic Organic Chemistry. MDPI, 1997. http://dx.doi.org/10.3390/ecsoc-1-02002.

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Rathod, Pravinsinh I., A. T. Oza, P. Predeep, Mrinal Thakur, and M. K. Ravi Varma. "Infrared Spectroscopy of Charge Transfer Complexes of Purines and Pyrimidines." In OPTICS: PHENOMENA, MATERIALS, DEVICES, AND CHARACTERIZATION: OPTICS 2011: International Conference on Light. AIP, 2011. http://dx.doi.org/10.1063/1.3643633.

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Xavier, Augusto L., Daniel S. Alexandrino, Emerson P. S. Falcão, Rajendra M. Srivastava, and Janaina V. dos Anjos. "A green, microwave-mediated, multicomponent synthesis of pyrimidine and pyrimidinone derivatives." In 14th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0024-1.

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Dotsenko, Victor, Vyacheslav Muraviev, Darya Lukina, and Vladimir Strelkov. "Synthesis of new spiro pyrido[3',2':4,5]thieno[3,2-d]pyrimidines." In The 21st International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2017. http://dx.doi.org/10.3390/ecsoc-21-04803.

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Syahri, Jufrizal, Rahmadini Syafri, Hasmalina Nasution, Della Pratiwi, Emmy Yuanita, and Beta Achromi Nurohmah. "Design of 2-Phenylamino Benzothiopyrano [4,3-D] Pyrimidines Compound as an Anticancer." In Proceedings of the International Conference of CELSciTech 2019 - Science and Technology track (ICCELST-ST 2019). Atlantis Press, 2019. http://dx.doi.org/10.2991/iccelst-st-19.2019.14.

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Deng, Jiac Hun, Na Jin, Zhong Qiang Wang, Shou Gen Yin, and Yu Lin Hua. "Organic Field Effect Transistors with Polarizable Active Layer of 2-(4-Hydroxyphenyl)-5-Pyrimidinol Thin Film." In 2008 2nd International Conference on Bioinformatics and Biomedical Engineering. IEEE, 2008. http://dx.doi.org/10.1109/icbbe.2008.240.

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Reports on the topic "Pyrimidinols"

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Wallace, Susan S. Structure/Function Analysis of DNA-glycosylases That Repair Oxidized Purines and Pyrimidines and the Influence of Surrounding DNA Sequence on Their Interactions. Office of Scientific and Technical Information (OSTI), 2005. http://dx.doi.org/10.2172/900301.

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