Academic literature on the topic 'QD Organic Chemistry 241-441'

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Dissertations / Theses on the topic "QD Organic Chemistry 241-441"

1

Oguzkaya, Funda. "Synthesis Of Macromolecular Catalyst Systems And Applications." Phd thesis, METU, 2011. http://etd.lib.metu.edu.tr/upload/12613565/index.pdf.

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SYNTHESIS OF MACROMOLECULAR CATALYST SYSTEMS AND APPLICATIONS Oguzkaya, Funda PhD., Department of Chemistry Supervisor: Prof. Dr. Cihangir Tanyeli September 2011, 144 pages The thesis mainly proposed to design macromolecular catalyst systems. Such catalysts should follow the way of &quot<br>Green Chemistry&quot<br>with including no metallic ions and have also the ability of reusability. Hence, nitroxide chemistry was chosen as the key point. Catalysts were synthesized with surely including TEMPO as the functional part as the most preferable nitroxide derivative. As a skeleton, norbornene
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2

Duygu, Arife Nese. "Synthesis Of Camptothecin Derivatives." Phd thesis, METU, 2005. http://etd.lib.metu.edu.tr/upload/3/12606302/index.pdf.

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This study presents synthetic studies on camptothecin, a potent antitumor agent in order to improve its stability and solubility without reducing its activity. The study consists of the modification of camptothecin at 20-OH position a new strategy for the targeted and controlled release of the drug and modification at C-7 position to overcome the stability and solubility problems of the free drug. In the first part of the study, the 20-OH functional group of camptothecin was replaced with an unsymmetrical benzoin derivative that is able to release the drug under photolysis at 350 nm. The new
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3

Demirci, Sema. "Synthesis Of Heteroaryl Substituted Dihydrofuran And Dihydropyran Derivatives By Green Chemistry Approach." Master's thesis, METU, 2009. http://etd.lib.metu.edu.tr/upload/2/12610966/index.pdf.

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The thesis subject is mainly involved in Green Chemistry approach. Thiophene, furan and pyridine carboxaldehydes were chosen as starting compounds and vinylation and allylation with Grignard reaction afforded the corresponding racemic heteroaryl substituted allylic and homoallylic alcohols. Subsequent resolution with enzymes (PS-Amano II, Lipozym and Novazym 435) gave enantiomerically enriched alcohols with the e.e. values varied between 65 and 99%. The absolute configurations of all substrates are known. As a result of O-allylation with the common procedure formed the feasible carbon backbone
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4

Emrullahoglu, Mustafa. "Novel Annulation Reactions For The Synthesis Of Substituted Pyrroles Darzens Reaction Of Acyl Phosphonates With &amp." Phd thesis, METU, 2009. http://etd.lib.metu.edu.tr/upload/3/12610338/index.pdf.

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In the first part of this thesis, it is aimed to develope methods for the synthesis of trisubstituted pyrrrole derivatives. 2-Aminopyrrroles, alkoxy and sulfonyl substittitued pyrrole derivatives as well as pirolinones show interesting biological activities and are precursor of well know drugs. Although there is a number of methods for the synthesis of pyrroles, the synthesis of 2-aminopyrroles is limited to few works and is not widely known. Therefore, it is still an important goal in organic chemistry to improve methods for the synthesis of multifunctionalized pyrrole derivatives and pyrroli
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5

Isik, Murat. "Synthesis Of Various Camphor-based Chiral Pyridine Derivatives." Master's thesis, METU, 2005. http://etd.lib.metu.edu.tr/upload/12605824/index.pdf.

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Chiral aromatic nitrogen heterocycles are finding many applications in asymmetric organic synthesis, particularly as ligands in the preparation of chiral metal complexes. Since camphor-based chiral auxiliaries are known to be especially effective, a number of pyridines fused to the camphor skeleton have been reported. It is well known that nicotinic acid and its derivatives exhibiting qualitatively the biological activity of nicotinamide, which acts as an electron acceptor in many biological redox reactions. In connection to our works, we attempted to develop short and convenient way to prepar
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6

Pinar, Ayse Nur. "Reaction Of Propargyl Aldehydes With Hydrazinium Salts: Synthesis Of Ferrocenyl And Phenyl Substituted Pyrazoles." Master's thesis, METU, 2008. http://etd.lib.metu.edu.tr/upload/3/12609769/index.pdf.

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Pyrazoles have been focus of a large number of investigations in the design and synthesis of novel biologically active agents that show remarkable medicinal activities. Although pyrazoles have been studied for over a century as an important class of heterocyclic compounds, they still continue to attract considerable attention due to the wide range of medicinal activities they possess. Recent studies have shown that combination of a ferrocenyl unit with structural features of pyrazoles can lead to products with enhanced or/and unexpected biological activity since several ferrocene derivatives h
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7

Karahan, Emrah. "Synthesis Of Furopyrrolone And Furopyridazinone Derivatives: A New Class Of Compounds." Master's thesis, METU, 2011. http://etd.lib.metu.edu.tr/upload/12612937/index.pdf.

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ABSTRACT SYNTHESIS OF FUROPYRROLONE AND FUROPYRIDAZINONE DERIVATIVES: A NEW CLASS OF COMPOUNDS Karahan, Emrah M.Sc., Department of Chemistry Supervisor: Prof. Dr. Metin Balci February 2011, 102 pages Furopyrrolone has a bicyclic structure consisting of furan and a pyrrolone ring. It is isoelectronic with isoindolinone which is also a heterocyclic organic compound. It has a bicyclic structure, consisting of a benzene ring fused to a five-membered nitrogen containing pyrrolone ring. Pyrrolones, pyrrolidines, pyrrolidinones, pyridazines and pyridazinones are precursors to many pharmaceutic
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8

Kilikli, Ahmet Alper. "Development Of New Synthetic Methodologies For Indole Derivatives: Chemistry Of Homophthalic Acid." Master's thesis, METU, 2010. http://etd.lib.metu.edu.tr/upload/3/12611521/index.pdf.

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Synthesizing nitrogen containing heterocyclic compounds is one of the leading research areas throughout the organic chemistry due to their significant activities on biological systems. Among the various biologically active molecules, indole derivatives are of prime importance on the grounds of their proven clinical roles. Objective of this study is to synthesize new indole derivatives those may contribute treatment of several diseases like their analogues via a recently developed synthetic methodology. Besides this, another objective is to observe and discuss effects of two different substitue
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9

Ozcan, Sevil. "Development Of New Synthetic Methodologies For The Synthesis Of Unusual Isocoumarin And Indole Derivatives:the Chemistry Of Homophthalic Acid." Phd thesis, METU, 2007. http://etd.lib.metu.edu.tr/upload/3/12608197/index.pdf.

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Many heterocyclic compounds containing nitrogen, oxygen and sulfur show wide range of physiological activities and their synthesis has always been attracted the interest of chemists. The aim of this research is to develop new synthetic methodologies leading to the synthesis of new derivatives of isocoumarines, indoles, isoquinolines, benzodiazepinones and quinazolines, which have been found to show important biological activities. Starting from homophthalic acid and bishomophthalic acid the corresponding acyl azides were proposed to be synthesized, which then would be used for the synthesis of
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10

Yilmaz, Mahmut Deniz. "Light Harvesting And Efficient Energy Transfer In Boron Dipyrrin (bodipy) Functionalized Perylene Diimide Dyads." Master's thesis, METU, 2006. http://etd.lib.metu.edu.tr/upload/2/12607376/index.pdf.

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An antenna for light harvesting is an organized multicomponent system in which several chromophoric molecular species absorb the incident light and channel the excitation energy to a common acceptor component. In this study, Click chemistry has been successfully applied in the synthesis of a bay region tetraboron dipyrrin (BODIPY) appended perylenediimide (PDI). This light-harvesting molecule presents a large cross section for the absorption of light in the visible region. Excitation energy is efficiently channeled to the perylenediimide core. This novel antenna system is the first demonstrati
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