Log in

Relevant bibliographies by topics / Qian family / Journal articles

To see the other types of publications on this topic, follow the link: Qian family.

Journal articles on the topic 'Qian family'

Author: Grafiati

Published: 28 July 2024

Last updated: 31 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Qian family.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Qian, Chang-Yuan, Yun Bu, Yan Dong, and Yun-Xia Luan. "Study on the Pauropoda from Tibet, China. Part I. The genera Decapauropus and Hemipauropus (Myriapoda)." ZooKeys 754 (April 30, 2018): 33–46. http://dx.doi.org/10.3897/zookeys.754.24210.

Full text

Abstract:

Three new species of family Pauropodidae: Decapauropusbiconjugarus Qian &amp; Bu, sp. n., D.tibeticus Qian &amp; Bu, sp. n. and Hemipauropusquadrangulus Qian &amp; Bu, sp. n. are described and illustrated from southeastern Tibet, China. The genus Hemipauropus is recorded for the first time from China. This is the second report of pauropods from Tibet.

APA, Harvard, Vancouver, ISO, and other styles

2

Qian, Chang-Yuan, Yun Bu, Yan Dong, and Yun-Xia Luan. "Study on the Pauropoda from Tibet, China. Part I. The genera Decapauropus and Hemipauropus (Myriapoda)." ZooKeys 754 (April 30, 2018): 33–46. https://doi.org/10.3897/zookeys.754.24210.

Full text

Abstract:

Three new species of family Pauropodidae: Decapauropus biconjugarus Qian & Bu, sp. n., D. tibeticus Qian & Bu, sp. n. and Hemipauropus quadrangulus Qian & Bu, sp. n. are described and illustrated from southeastern Tibet, China. The genus Hemipauropus is recorded for the first time from China. This is the second report of pauropods from Tibet.

APA, Harvard, Vancouver, ISO, and other styles

3

van Ess, Hans. "Praise and Slander: The Evocation of Empress Lü in the Shiji and the Hanshu." NAN NÜ 8, no. 2 (2006): 221–54. http://dx.doi.org/10.1163/156852606779969824.

Full text

Abstract:

AbstractThis article contains a close reading of the accounts of Empress Lü in the Shiji and the Hanshu. Its main argument is that the views of Sima Qian and Ban Gu about her are marked by considerable differences, although they may seem alike at first sight. For Sima Qian, the main feature dominating the life of Empress Lü was fear for herself and for her clan, whereas Ban Gu attributed her actions to naked cruelty. According to Sima Qian, the battle between the Lü family and those members of the Liu family who put Emperor Wen on the throne was one between two equal competitors, whereas for B

APA, Harvard, Vancouver, ISO, and other styles

4

Yang, Xiao, and Yu-Zhou Du. "Further studies on the morphology of three species of Rhopalopsole (Plecoptera, Leuctridae)." Biodiversity Data Journal 13 (May 23, 2025): e154980. https://doi.org/10.3897/BDJ.13.e154980.

Full text

Abstract:

<i>Rhopalopsole</i> Klapálek, 1912, is a species-rich genus in the family Leuctridae, with more than 80 valid species known from the Oriental and eastern Palaearctic Regions.We recently examined specimens of <i>Rhopalopsole</i> Klapálek, 1912 from Hubei and Guizhou, China and provided a supplementary description of <i>Rhopalopsole ampulla</i> Du & Qian, 2011, <i>Rhopalopsole exiguspina</i> Du & Qian, 2011 and <i>Rhopalopsole memorabilis</i> Qian & Du, 2014. Additionally, we provide new images of these species to facilitate identification.

APA, Harvard, Vancouver, ISO, and other styles

5

Nylan, Michael. "Sima Qian: A True Historian?" Early China 23 (1998): 203–46. http://dx.doi.org/10.1017/s0362502800000985.

Full text

Abstract:

This essay seeks to argue the merits of one approach to reading theShiji, which casts the complex text more as a product of contemporary religious beliefs than as the product of either thetaishi's individual genius or desire for historical objectivity. By the religious reading, Sima Qian fulfilled some part of his filial obligations when he honored his father's dying wish to “continue our ancestors” by bringing together the tales they had gathered. Equally importantly, insofar as Sima Qian had restored to life an array of remarkable men and women from the Central States, he lived in the pious

APA, Harvard, Vancouver, ISO, and other styles

6

Yan, Zhenzhen. "Qian Family Learning under the Influence of the Modern Southern Jiangsu Academic Style." Yixin Publisher 1, no. 1 (2024): 55–63. http://dx.doi.org/10.59825/jlls.2024.1.1.55.

Full text

Abstract:

钱基博和其家族在苏南地区的文化氛围和教育传统中成长，形成了独特的学术和教育理念。本文通过分析钱基博的成长环境、家族教育和苏南学风，探讨其对钱基博及其后代学术发展的影响。研究发现，苏南地区重视文化传承和经世致用的学风，促使钱基博及其家族在学术和教育上取得了显著成就。钱氏家族的教育理念不仅体现在对诗书的重视上，还强调学问的实用性和社会责任感。这种教育传统对钱基博的学术思想形成和治学方法产生了深远影响，并通过家族传承继续影响后代。本文旨在揭示家族教育和文化传承在个人学术成就中的重要性，为现代社会如何继承和发扬优秀的家族文化提供借鉴。

APA, Harvard, Vancouver, ISO, and other styles

7

Farooq, Rashid, Mehar Ali Malik, Qudsia Naureen, and Shariefuddin Pirzada. "On the nullity of a family of tripartite graphs." Acta Universitatis Sapientiae, Informatica 8, no. 1 (2016): 96–107. http://dx.doi.org/10.1515/ausi-2016-0006.

Full text

Abstract:

Abstract The eigenvalues of the adjacency matrix of a graph form the spectrum of the graph. The multiplicity of the eigenvalue zero in the spectrum of a graph is called nullity of the graph. Fan and Qian (2009) obtained the nullity set of n-vertex bipartite graphs and characterized the bipartite graphs with nullity n − 4 and the regular n-vertex bipartite graphs with nullity n − 6. In this paper, we study similar problem for a class of tripartite graphs. As observed the nullity problem in tripartite graphs does not follow as an extension to that of the nullity of bipartite graphs, this makes t

APA, Harvard, Vancouver, ISO, and other styles

8

Hodnett, Kathleen, Heng-Hsing Hsieh, and Paul Van Rensburg. "Nonlinearities In Stock Return Prediction: A Blended Approach." Journal of Applied Business Research (JABR) 29, no. 1 (2012): 7. http://dx.doi.org/10.19030/jabr.v29i1.7551.

Full text

Abstract:

<span style="font-family: Times New Roman; font-size: small;"> </span><p style="margin: 0in 0.5in 0pt; text-align: justify; tab-stops: 415.05pt; mso-layout-grid-align: none;" class="MsoNormal"><span style="font-family: Times New Roman;"><span style="font-size: 10pt; mso-fareast-language: ZH-HK;">Our prior research indicates that there are periods within which nonlinear stock selection models outperform their linear counterparts in the South African equity market. In order to explore the nonlinearities in stock return prediction, we propose a blended stock selectio

APA, Harvard, Vancouver, ISO, and other styles

9

Aleman, Ezequiel, and Larysa Nadolny. "Integration of Video Games To Support the FCS Education Food Production Standards." Journal of Family & Consumer Sciences 113, no. 2 (2021): 46–49. http://dx.doi.org/10.14307/jfcs113.2.46.

Full text

Abstract:

Digital games can provide fun, motivating, and challenging experiences for students in the classroom. Recent research on educational games has shown that game play can positively influence academic achievement, engagement, and 21st century skills (Abdul Jabbar & Felicia, 2015; Qian & Clark, 2016). When playing games, students solve problems, collaborate with peers, and practice new skills—all within a digital environment. There are multiple games that simulate preparing and serving food. Generally, players are tasked to prepare food based on the requests of customers. Ingredients are p

APA, Harvard, Vancouver, ISO, and other styles

10

Zhang, Qianqian, and Wue Hiong Ser. "A Preliminary Exploration of the Academic Origins and Developments of Duan Yucai." ERUDITE: Journal Of Chinese Studies And Education 4, no. 2 (2023): 1–23. http://dx.doi.org/10.37134/erudite.vol4.2.1.2023.

Full text

Abstract:

Duan Yucai was renowned philologist and scholar during the Qianlong and Jiaqing periods of the Qing Dynasty. He possessed extensive knowledge and authored numerous works, with his masterpiece Shuo Wen Jie Zi Zhu gaining great recognition in academic circles. Duan Yucai’s family tradition is virtuous and studious, and he learned from Dai Zhen, inherited and developed the tradition of philological research, making significant contribution in both practical and theoretical aspects. He had close interactions and discussions with scholars such as Wang Niansun and Qian Daxin. Duan Yucai also activel

APA, Harvard, Vancouver, ISO, and other styles

11

Vinogradova, Tatiana I., and Ekaterina A. Zavidovskaia. "Preliminary Findings about the “Okulich” Collection of Chinese Popular Prints (MAE No. 3676) in the Peter the Great Museum of Anthropology and Ethnography (The Kunstkamera)." Письменные памятники Востока 17, no. 3 (2020): 67–88. http://dx.doi.org/10.17816/wmo46853.

Full text

Abstract:

There are several collections of Chinese popular woodblock prints nianhua in the fund of the Peter the Great Museum of Anthropology and Ethnography, Russian Academy of Sciences (the Kunstkamera) acquired from different collectors. The paper addresses the so-called Okulich collection (MAE No. 3676) consisting of 250 original titles, most of which possess undoubted artistic value. According to the dated sheets, the prints were produced in the last years of the 19th century, and no later than 1904. We only know that, in 1928, a man named Okulich donated these prints to the Kunstkamera. Two groups

APA, Harvard, Vancouver, ISO, and other styles

12

趙厚均, 趙厚均. "乾嘉閨秀的才名意識與文化轉型：以駱綺蘭為中心". 中正漢學研究 32, № 32 (2018): 143–60. http://dx.doi.org/10.53106/2306036020181200320006.

Full text

Abstract:

<p>經過明末清初的才德之辨，閨秀文學發展到乾嘉時期，進入了一個新的階段。此期的閨秀有著更強的才名意識，她們充分運用文壇領袖所掌握的文化權力，通過拜師等舉措拓展交往空間，從而與著名文人唱和、題贈，躋身文壇，顯揚聲名。駱綺蘭通過結交袁枚、王文治和王昶等，以畫作、詩集遍求題贈，並編選《聽秋軒贈言》和《聽秋軒閨中同人集》，得以聲名鵲起；歸懋儀在乾嘉文人與閨秀之間構築了一個非常龐大的交游網絡，她執著於詩史留名的願望，成功藉助男性文人的資助，令詩稿付梓，並憑藉才名遊走於江浙間擔任閨塾師，承擔起養家的重任；汪端則欲通過選詩修史來達到不朽，其《元明逸史》的撰寫和詩集中大量的詠史詩，可見其修史的努力，編選《明三十家詩選》更見其不凡的識見。吳藻創作雜劇《喬影》，並繪《飲酒讀騷圖》，體現出懷才不遇的苦悶和強烈的性別意識。總體而言，乾嘉閨秀已經不滿足于內闈狹小的空間，做出了跨越閨門的種種努力，是晚清民國閨秀文化近代轉型的先聲。</p> <p>&nbsp;</p><p>Following the debates on female talent during the late Ming and early Qing eras, women&rsquo;s literary production entered a new stag

APA, Harvard, Vancouver, ISO, and other styles

13

Pomeroy, Mary Louise, Yiqing Qian, and Katherine Ornstein. "MEASURING NATIONAL TRENDS IN SOCIAL ISOLATION AND LONELINESS AMONG OLDER ADULTS AND THEIR CAREGIVERS." Innovation in Aging 8, Supplement_1 (2024): 247. https://doi.org/10.1093/geroni/igae098.0800.

Full text

Abstract:

Abstract Social isolation and loneliness have negative implications for the health and care of older adults. Few studies have examined longitudinal patterns of social isolation and loneliness among older adults, or how these experiences are shared by caregivers and personal care networks. This research symposium uses various survey data methods to highlight trends in social isolation, loneliness, and care isolation among older adults and their caregivers. First, we report on trends in social isolation and loneliness over time. Leveraging six waves of data from the Longitudinal Ageing Study Ams

APA, Harvard, Vancouver, ISO, and other styles

14

Qian, Chen, Qian Yang, HyoYoung Kim, et al. "Abstract B014: ONECUT2 activates diverse drug-resistant phenotypes in prostate cancer." Cancer Research 83, no. 11_Supplement (2023): B014. http://dx.doi.org/10.1158/1538-7445.prca2023-b014.

Full text

Abstract:

Abstract BACKGROUND. Prostate cancer (PC) cells can escape from lineage confinement and be reprogrammed to a drug-resistant, high-plasticity state, however the mechanism underlying this process is not understood. Our group identified the HOX/CUT transcription factor ONECUT2 (OC2) as a mediator of metastatic castration-resistant PC (mCRPC) that can be inhibited with a novel family of small molecules. OC2 was shown to be a lineage plasticity driver that promotes neuroendocrine prostate cancer (NEPC). In this study, we sought to uncover the mechanism whereby OC2 exerts effects on lineage plastici

APA, Harvard, Vancouver, ISO, and other styles

15

Zhou, Yixing, Shilan Wu, Huanchen Wang, Yoichi Hayakawa, Gary S. Bird, and Stephen B. Shears. "Activation of PLC by an endogenous cytokine (GBP) in Drosophila S3 cells and its application as a model for studying inositol phosphate signalling through ITPK1." Biochemical Journal 448, no. 2 (2012): 273–83. http://dx.doi.org/10.1042/bj20120730.

Full text

Abstract:

Using immortalized [3H]inositol-labelled S3 cells, we demonstrated in the present study that various elements of the inositol phosphate signalling cascade are recruited by a Drosophila homologue from a cytokine family of so-called GBPs (growth-blocking peptides). HPLC analysis revealed that dGBP (Drosophila GBP) elevated Ins(1,4,5)P3 levels 9-fold. By using fluorescent Ca2+ probes, we determined that dGBP initially mobilized Ca2+ from intracellular pools; the ensuing depletion of intracellular Ca2+ stores by dGBP subsequently activated a Ca2+ entry pathway. The addition of dsRNA (double-strand

APA, Harvard, Vancouver, ISO, and other styles

16

Petrović, Elena, Karolina Vrandečić, Jasenka Ćosić, Tamara Siber, and Sara Godena. "Antifungal Efficacy of Essential Oils and Their Predominant Components Against Olive Fungal Pathogens." Agriculture 15, no. 3 (2025): 340. https://doi.org/10.3390/agriculture15030340.

Full text

Abstract:

The antifungal effectiveness of essential oils (EOs) and their predominant components were tested on 14 phytopathogenic fungi isolated from olive trees. Commercial EOs from holy basil (Ocimum tenuiflorum L.), Chinese cinnamon (Cinnamomum aromaticum Ness), lemon (Citrus × limon), peppermint (Mentha × piperita L.), oregano (Origanum compactum Benth), and thyme (Thymus vulgaris L.) and components eugenol, e-cinnamaldehyde, limonene, menthol, carvacrol, and thymol were used. Antifungal efficacy was tested on six species from the Botryosphaeriaceae family: Botryosphaeria dothidea (Moug. ex Fr.) Ces

APA, Harvard, Vancouver, ISO, and other styles

17

Wu, Minghui, Chaojie Ma, Minghan Fang, and Saicheng Fang. "On the Civil Legal Issues of ‘Haunted House’ Sales Contract - Take Peng Qian et al. and Chen Yuanhui et al. House Sales Contract Dispute Case as an Example." International Journal of Asian Social Science Research 1, no. 2 (2024): 8–20. http://dx.doi.org/10.70267/xqs54s36.

Full text

Abstract:

As a vital transaction in daily life, house sale is not only related to the property rights and interests of buyers and sellers, but also carries the peace and happiness of the family. However, when the target house of the transaction is labeled as a ‘haunted house’ -that is, there have been incidents such as suicide and homicide in the house, it often causes the buyers and sellers to fall into deep disputes and troubles. ‘Haunted house’ is not a legal concept, but it carries deep folk traditional concepts and psychological shadows, which has a significant impact on the purchaser’s willingness

APA, Harvard, Vancouver, ISO, and other styles

18

Chatterjee, Avradip, Brad Gallent, Madhusudhanarao Katiki, et al. "Abstract 5767: DNA binding mechanism of prostate cancer target ONECUT2." Cancer Research 84, no. 6_Supplement (2024): 5767. http://dx.doi.org/10.1158/1538-7445.am2024-5767.

Full text

Abstract:

Abstract Transcription factors (TF) are essential determinants of gene regulation and their aberrant expression frequently drive cancers. The binding of TFs to cognate DNA is central to their role in gene regulation. An understanding of their DNA binding mechanism is, therefore, of fundamental and therapeutic relevance. Generally, TFs bind DNA through defined DNA binding domains. The CUT and homeodomain are two such evolutionarily conserved elements found paired in multiple transcription factor families including ONECUT (OC), POU, CUX and SATB. However, the mechanism of cross-talk between the

APA, Harvard, Vancouver, ISO, and other styles

19

Hu, Yeting, Wei Lu, Chengcheng Liu, et al. "Abstract 1063: IsomiR relative proportion (IRP) within miRNA family as an efficient biomarker for noninvasive colorectal cancer detection." Cancer Research 84, no. 6_Supplement (2024): 1063. http://dx.doi.org/10.1158/1538-7445.am2024-1063.

Full text

Abstract:

Abstract Background: Cell free miRNA has been widely used for disease diagnosis, particularly in cancers. The latest research has also demonstrated that isomiRs (isoform miRNAs) can serve as superior markers, displaying enhanced diagnostic performance in cancer diagnosis. However, the low detection sensitivities of miRNA/isomiRs in previous methods in plasma have limited their broad implementations for screening purpose. In this study, we propose a new isomiRs feature of isomiR relative proportion (IRP), which was validated with high performance in Colorectal Cancer (CRC) early diagnosis. Meth

APA, Harvard, Vancouver, ISO, and other styles

20

Nan, Gun. "Wufeng Academy and the Deep Dissemination of Yangming School in Jinhua in the Middleand Late Ming Dynasty." Institute of Korean Cultural Studies Yeungnam University 82 (December 31, 2022): 5–25. http://dx.doi.org/10.15186/ikc.2022.12.31.01.

Full text

Abstract:

명대 정덕(正德)-가정(嘉靖) 연간, 응전(應典)을 대표 인물로 삼는 용강(永康) 사인(士人)들은 금화(金華) 지역의 학술을 전승한 것 외에도, 소흥(紹興)에 가서 왕양명을 스승으로 모셨고 양명의 심학(心學)을 무학(婺學)의 전통 속에 편입함으로써 매우 독특한 오봉(五峰) 양명학자 집단을 형성하였다. 응전(應典), 정문덕(程文德), 정재(程梓), 노가구(盧可久) 등 양명 제자들의 노력을 통해, 오봉서원은 점차 금화 일대에서 가장 영향력 있는 양명학 중심지가 되었다. 양명 심학은 오봉의 제자, 즉 두유희(杜維熙), 진시로(陳時芳), 진기은(陳其蒽) 등이 일으킨 향회(鄉會), 사회(祠會), 가회(家會)를 통해 용강 오봉의 동양(東陽)으로의 심층적 전파를 이루게 된다. 응전, 정문덕, 노가구 등 향리 문중의 지원과 더불어, 오봉의 강학 활동은 청대 건륭(乾隆) 연간까지 지속되었다  During the Zhengde to Jiajing years of the Ming Dynasty, Yongkang scholars headed by Ying Dian went to Shaoxing to worship Wang Yangming as a teache

APA, Harvard, Vancouver, ISO, and other styles

21

Saad, A., N. Hafdhouni, R. Ben Tekaya, et al. "AB1755-PARE EVALUATION OF THE FRAGILITY OF ELDERLY PATIENTS HOSPITALIZED IN THE RHEUMATOLOGY DEPARTMENT." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 2112.1–2112. http://dx.doi.org/10.1136/annrheumdis-2023-eular.2636.

Full text

Abstract:

BackgroundFragility is defined by a clinical syndrome that reflects a decrease in physiological capacities altering the mechanisms of adaptation to stress[1]. Elderly patients hospitalized in the rheumatology department are at risk of significant fragility.ObjectivesThe aim of our study is to evaluate the fragility of elderly patients considering the bio-psycho-social parameters.MethodsProspective study started in July 2022 in the rheumatology department including 40 patients who were subject to questionnaires assessing their fragility and quality of life.Results40 patients were collected incl

APA, Harvard, Vancouver, ISO, and other styles

22

Zhao, Xin, Qun Li, Qian Wu, et al. "Abstract 1739: Identification of a potent and selective KAT6A/6B inhibitor: HW321005 exhibits strong antitumor activity in KAT6A-high ER+/HER2− breast cancer." Cancer Research 85, no. 8_Supplement_1 (2025): 1739. https://doi.org/10.1158/1538-7445.am2025-1739.

Full text

Abstract:

KAT6A and its paralog KAT6B are histone lysine acetyltransferases (HATs) that regulate gene transcription via the acetylation of histones. Dysregulation of KAT6 leads to lineage-specific gene expression changes in cancer. Overexpression of KAT6 is associated with poorer clinical outcomes in ER+/HER2− breast cancers. Dysregulation of KAT6 activity, including gene amplification, overexpression, fusion, and mutation, is observed in various cancers, including breast cancer. We have developed potent and selective small molecule inhibitors targeting KAT6A/6B. Our proprietary compound, HW321005, inhi

APA, Harvard, Vancouver, ISO, and other styles

23

Hodnett, Kathleen, Heng-Hsing Hsieh, and Paul Van Rensburg. "Equity Style Payoffs And Stock Return Predictability: Evidence From The South African JSE Securities Exchange." Journal of Applied Business Research (JABR) 28, no. 4 (2012): 605. http://dx.doi.org/10.19030/jabr.v28i4.7044.

Full text

Abstract:

<span style="font-family: Times New Roman; font-size: small;"> </span><p style="margin: 0in 0.5in 0pt; text-align: justify; mso-pagination: none;" class="MsoNormal"><span style="font-family: Times New Roman;"><span style="color: black; font-size: 10pt; mso-themecolor: text1; mso-fareast-language: ZH-HK;">This paper undertakes to examine the structure of the payoffs to style attributes on the JSE Securities Exchange over the period from 1997 to 2007. Adopting the methodology of Haugen and Baker (1996), two expected return multifactor models are constructed to predi

APA, Harvard, Vancouver, ISO, and other styles

24

Wee, Shianlin, Dario Gomez Vazquez, Xiliang Lian, Akhil Tayal, Mathieu Salanne, and Maria R. Lukatskaya. "Elucidating the Interactions between Different Transition Metal Cations and Ti3C2Tx MXene through Intercalation Method for Electrochemical Applications." ECS Meeting Abstracts MA2024-01, no. 47 (2024): 2625. http://dx.doi.org/10.1149/ma2024-01472625mtgabs.

Full text

Abstract:

MXenes, are a family of two-dimensional (2D) transition metal carbides, nitrides and/ or carbonitrides.[1] The intercalation of different metal cations and organic molecules into MXene for tuning MXenes’ electronic and electrochemical properties have been widely reported.[2] [3] [4] However, transition metals (TMs) which have distinct electrochemical behaviors[5] [6] have not been explored in the literature of MXenes’ intercalation. Therefore, we herein compared the intercalation effects of different TM cations on Ti3C2Tx, for offering a general insight on the influences of multi-valent, redox

APA, Harvard, Vancouver, ISO, and other styles

25

Li, Qun, Yang Zang, Xin Zhao, et al. "Abstract 1482: Discovery of HW221043, a potent and orally bioavailable KIF18A inhibitor for treating chromosomal instability in cancer." Cancer Research 85, no. 8_Supplement_1 (2025): 1482. https://doi.org/10.1158/1538-7445.am2025-1482.

Full text

Abstract:

Abstract Background: KIF18A, a molecular motor protein, is crucial for regulating microtubule length, essential for maintaining proper cell function and division. Chromosomal instability (CIN) significantly contributes to cancer progression and is targeted by emerging therapies such as PARP inhibitors, which exploit synthetic lethality in cancer cells. CIN resulting from whole genome duplication (WGD) is associated with poor outcomes and metastatic disease, with cancers demonstrating sensitivity to spindle assembly checkpoint disruption. This makes KIF18A a promising target in this drug class.

APA, Harvard, Vancouver, ISO, and other styles

26

Verma, Madhurima, and Dilraaj Kaur. "Stigma and Discrimination Faced by Women Living with HIV/AIDS (WLHA)." International Journal of Research and Innovation in Social Science IX, no. V (2025): 884–94. https://doi.org/10.47772/ijriss.2025.90500073.

Full text

Abstract:

Human Immunodeficiency Virus (HIV) and Acquired Immunodeficiency Syndrome (AIDS) continue to be among the most pressing global public health challenges. According to UNAIDS (2020), approximately 38 million people worldwide are living with HIV, with around 5.8 million of them residing in Asia. In India alone, the National AIDS Control Organization (NACO, 2020) reports that 2.349 million people are living with HIV, making it the country with the third-highest number of cases globally, with an estimated HIV prevalence rate of 0.22%. Despite significant advancements in public health interventions,

APA, Harvard, Vancouver, ISO, and other styles

27

Teng, Fei, Huanhuan Guo, Hongjun Li, et al. "Abstract 4769: Characterization of novel humanized FGFR2b antibody-based ADCs site-specifically conjugated with topoisomerase I inhibitor payload in preclinical tumor models." Cancer Research 85, no. 8_Supplement_1 (2025): 4769. https://doi.org/10.1158/1538-7445.am2025-4769.

Full text

Abstract:

Abstract Background: Fibroblast growth factor receptor 2 IIIb (FGFR2b), one of the four FGFR family members that encode transmembrane receptor tyrosine kinases, is overexpressed in a variety of cancers, such as gastric/GEJ (29%), esophageal (41%), squamous NSCLC (31%), TNBC (13%), ovarian (40%), endometrial (86%), cervical (80%), colorectal (62%), and cholangiocarcinoma (22%). We have developed a FGFR2b-targeting ADC (TST105) with a novel topoisomerase I inhibitor payload by using glycotransferase mediated site-specific conjugation and characterized its in vitro and in vivo anti-tumor activity

APA, Harvard, Vancouver, ISO, and other styles

28

Sik, Ruoh Yih. "INCORPORATING CHINESE TRADITIONAL CULTURE IN PRIMARY SCHOOL CHINESE TEXTBOOKS." International Journal of Humanities, Philosophy and Language 4, no. 16 (2021): 16–46. http://dx.doi.org/10.35631/ijhpl.416002.

Full text

Abstract:

"Where there are Chinese people, there is Chinese education". The Malaysian Chinese ancestors practised Chinese education in Malaysia since their arrival and with their efforts, Malaysia has the most comprehensive and systematic Chinese education in Southeast Asia. It is also considered the country that has preserved Chinese culture the best (Qian, 2017). Since 2011, the Chinese language has been offered as an elective subject in the standards-based curriculum for primary school (KSSR) syllabus. Since introducing Chinese into classrooms, there have been two versions of Chinese textbooks for th

APA, Harvard, Vancouver, ISO, and other styles

29

Zhang, Yuxing, Chundao Yang, Huijie Guo, et al. "Abstract 457: QLS1304, a highly potent and selective KAT6A/B inhibitor treating ER+HER2- breast cancer." Cancer Research 85, no. 8_Supplement_1 (2025): 457. https://doi.org/10.1158/1538-7445.am2025-457.

Full text

Abstract:

Abstract KAT6A and KAT6B, members of the MYST family of lysine acetyltransferases, are implicated in estrogen receptor-positive (ER+) breast cancer. KAT6A amplification occurs in about 10% of these patients, linking to overexpression and poorer outcomes. KAT6B is known to be functionally redundant with KAT6A in regulating levels of H3K23Ac, although its specific role in ER+HER2- breast cancer is not well understood. The simultaneous inhibition of KAT6A and KAT6B may lead to a more profound suppression of histone acetylation. Thus, the development of a dual inhibitor targeting KAT6A and KAT6B h

APA, Harvard, Vancouver, ISO, and other styles

30

Zhao, Zibo, Sarah Gold, Yuki Aoi, et al. "Abstract 4103: MLL4/COMPASS dysfunction in cancer and treatment." Cancer Research 85, no. 8_Supplement_1 (2025): 4103. https://doi.org/10.1158/1538-7445.am2025-4103.

Full text

Abstract:

Epigenetic status-altering mutations in chromatin-modifying enzymes are a feature of human diseases, including many cancers. We investigated cellular dependencies, or vulnerabilities, that arise when enhancer function is compromised by loss of the frequently mutated COMPASS family members MLL3 (KMT2C) and MLL4 (KMT2D). We performed a CRISPR dropout screen that revealed a targetable metabolic dependency arising from epigenetic factor deficiency, identifying potential therapies for cancers with epigenetic alterations secondary to MLL3/4-COMPASS dysfunction. We identified strong evidence that the

APA, Harvard, Vancouver, ISO, and other styles

31

Teng, Fei, Huanhuan Guo, Hongjun Li, et al. "Abstract P3-06-30: Novel Humanized LIV-1 Antibody Based ADCs Conjugated with Topoisomerase I Inhibitor Payloads Displayed Significantly Higher Anti-tumor Activities than MMAE based ADCs in TNBC Tumor Models." Clinical Cancer Research 31, no. 12_Supplement (2025): P3–06–30—P3–06–30. https://doi.org/10.1158/1557-3265.sabcs24-p3-06-30.

Full text

Abstract:

Abstract LIV-1 is a member of the zinc transporter family and an estrogen-regulated gene in metastatic breast cancer. While normal tissue expression is limited, LIV-1 was found to be overexpressed in a high prevalence in breast cancer (93%), as well as in melanoma (82%), prostate (72%), ovarian (48%) and uterine (30%) cancers. LIV-1 is considered as one of the attractive cell surface targets for developing ADC therapeutics. To develop next generation LIV1 targeting ADC, we generated 48D6, a proprietary novel humanized anti-LIV-1 mAb with high affinity, specificity, internalization ability, uni

APA, Harvard, Vancouver, ISO, and other styles

32

Zhang, Donia. "Pingyao Historic City and Qiao Family Courtyard." Journal of Chinese Architecture and Urbanism 4, no. 1 (2022): 1–19. http://dx.doi.org/10.36922/jcau.v4i1.47.

Full text

Abstract:

Historic cities all over the world are facing challenges on how to best preserve their architectural heritage. We need good examples to follow. This study explores the historic city of Pingyao in China’s Shanxi Province, and the Qiao Family Courtyard in Qiaojiapu Village of Qi County nearby. Pingyao is a representative of northern Chinese city planning and vernacular architecture during the Ming (1368‒1644) and Qing (1644‒1911) dynasties, and it became a UNESCO World Heritage Site in 1997. Qiao Family Courtyard is famous not only because of its majestic architectural compound and exquisite cra

APA, Harvard, Vancouver, ISO, and other styles

33

Piya, Sujan, Seemana Bhattacharya, Hong Mu, et al. "Disruption of NOTCH1-MYC-CD44 Axis Targets Leukemia Initiating Cells (LIC) in T-ALL." Blood 132, Supplement 1 (2018): 890. http://dx.doi.org/10.1182/blood-2018-99-115692.

Full text

Abstract:

Abstract Background: Persistence of leukemia initiating cells (LIC) in T acute lymphoblastic leukemia (T-ALL) results in relapse in 20- 25% of pediatric and over 50% of adult patients1. LIC are characterized by high CD44 expression and low reactive oxygen species (ROS) levels 2, 3. T-ALL LIC maintain low ROS by cystine/glutamate anti-porter complex of which CD44 is a key component 2, 4. CD44 also interacts with microenvironmental components; hyaluronic acid, osteopontin, fibronectin etc. NOTCH1 transcriptionally upregulates CD44/MYC by binding the upstream 'super-enhancer' sites. BRD4, a membe

APA, Harvard, Vancouver, ISO, and other styles

34

Liu, Shan, Xiaona Fang, Jie Luo, et al. "Abstract 2445: PPM1G enhances hepatocellular carcinoma stemness via interacting with YBX1." Cancer Research 83, no. 7_Supplement (2023): 2445. http://dx.doi.org/10.1158/1538-7445.am2023-2445.

Full text

Abstract:

Abstract PPM1G is a member of protein phosphatase family, marked as Mg2+/Mn2+ dependent 1G. PPM1G protein mainly has three domains: phosphatase domains at both ends and acidic domain (AD) in the middle. It was highly expressed in both embryonic stem cells and hepatocellular carcinoma (HCC) by mRNA-seq data. From pan-cancer view, it was up-regulated in tumor tissue of 24 pan-cancer types and predicted worse overall survival (OS) for 9 cancers. In GSE40267 dataset, PPM1G overexpressed significantly in lung metastasis HCC patients than patients without metastasis. And both from TCGA and ICGC-JP d

APA, Harvard, Vancouver, ISO, and other styles

35

Zhong, Chen, You Xue Wu, Xi Yun Zhang, et al. "Abstract 3138: Discovery of AT65474, a highly selective anti-CLDN6 ADC with a proprietary payload." Cancer Research 84, no. 6_Supplement (2024): 3138. http://dx.doi.org/10.1158/1538-7445.am2024-3138.

Full text

Abstract:

Abstract CLDN6 is a membrane-bound oncofetal protein and a promising target for cancers such as ovarian and testicular cancer. CLDN6 shares high sequence homology with other CLDN family members which are expressed in normal tissues, making a high degree of selectivity required for CLDN6-targeting therapies. In particular, CLDN6 is closest to CLDN9 in sequence with a difference of only three residues in the extracellular loops, making it challenging to generate a highly selective antibody. We report the development of a humanized anti-CLDN6 antibody with high affinity and high selectivity for t

APA, Harvard, Vancouver, ISO, and other styles

36

Cai, Congcong, Shiya Zhu, Chunlin Chen, et al. "Abstract 1756: A fully characterized KIF18A inhibitor with superior potency and good druggability ready for IND application." Cancer Research 85, no. 8_Supplement_1 (2025): 1756. https://doi.org/10.1158/1538-7445.am2025-1756.

Full text

Abstract:

About ∼90% of the solid tumors and ∼75% of the hematologic malignancies are aneuploidy. The process that gives rise to aneuploidy is chromosomal instability (CIN), characterized by chromosome mis-segregation and other mitotic aberrations. KIF18A (kinesin family member 18A), part of the kinesin family of motor proteins, is expressed in the G2/M phase of the cell cycle and regulates chromosome positioning during cell division. Genetic depletion of KIF18A impacts the chromosome alignment, elongation of mitotic spindles, and traps chromosomally unstable tumor cells in mitosis, while having negligi

APA, Harvard, Vancouver, ISO, and other styles

37

Tong, Yan-Feng, and Shu-Qiang Li. "Symphytognathidae (Araneae), a spider family newly recorded from China." Zootaxa 1259 (December 31, 2006): 33–38. https://doi.org/10.5281/zenodo.173149.

Full text

APA, Harvard, Vancouver, ISO, and other styles

38

Qian, Feng, Lei Dou, Kaixin Wang та ін. "Abstract A070: Time-Dependent Oxidation and Aggregation of Vimentin upon Binding by β-lap Induced Immunogenic Cell Death". Cancer Research 84, № 17_Supplement_2 (2024): A070. http://dx.doi.org/10.1158/1538-7445.pancreatic24-a070.

Full text

Abstract:

Abstract β-lapachone (β-lap) has been demonstrated as an NAD(P)H:quinone oxidoreductase1 (NQO1) bioactivatable compound. It initiated a futile redox cycle catalyzed by NQO1, resulting in reactive oxygen species (ROS) generation, with consumption of the reductive NAD(P)H. After a 4-h pulse of sufficiently lethal dose of β-lap, high levels of ROS diffused into nuclei to induce tumor-selective DNA damage and programmed necrosis in cancers overexpressing NQO1. Recently, our experiments showed that prolonged low dose β-lap administration exerted significant and NQO1 independent antitumor efficacy i

APA, Harvard, Vancouver, ISO, and other styles

39

Wang, Chuan, Yamin Wang, Xinling Zhang та ін. "Abstract 2953: CS5006: A novel integrin β4-targeted antibody-drug conjugate (ADC) with robust antitumor activity in preclinical studies". Cancer Research 85, № 8_Supplement_1 (2025): 2953. https://doi.org/10.1158/1538-7445.am2025-2953.

Full text

Abstract:

Abstract Background: The integrins are a family of cell surface receptors existing as heterodimers formed with one α subunit and one β subunit, and there are 24 heterodimers identified so far. These receptors play diverse roles in cellular adhesion, motility, and cytokinesis. Integrin β4 (ITGB4), also known as CD104, binds to integrin α6 (ITGA6) to form α6β4 integrin heterodimer that is recognized as a ligand of laminin and plays a critical role in strengthening and stabilizing the skin. The cytoplasmic tail of ITGB4 contains approximately 1000 amino acids which is longer than any other integr

APA, Harvard, Vancouver, ISO, and other styles

40

Tong, Ho-kin. "The Ancient Chinese Views of Family Education Recorded in Pre-Qin (before 221 BC) Confucian Classics." Journal of Arts and Humanities 6, no. 5 (2017): 42. http://dx.doi.org/10.18533/journal.v6i5.1166.

Full text

Abstract:

<p>The Pre-Qin family education is a long neglected but important research topic in understanding Chinese education and culture. Although Chinese traditional family education is mostly under the influence of Confucianism there is not sufficient discussion in the Pre-Qin period as there are only scattered records related to this topic in various Pre-Qin classics. In addition, most research outputs in the field are on “jiaxun” (family instruction) which normally refers to family seniors’ commandments to their juniors from a cultural perspective. However, “jiating jiaoyu” (family education)

APA, Harvard, Vancouver, ISO, and other styles

41

Xuan, Qiang, Lorenzo Prendini, Michael S. Engel, Chenyang Cai, and Diying Huang. "Extinct scorpion family Chaerilobuthidae from Mid-Cretaceous Burmese amber reinterpreted as subfamily of extant family Pseudochactidae (Chelicerata: Scorpiones)." Zoological Journal of the Linnean Society 203, no. 1 (2025): 1–60. https://doi.org/10.1093/zoolinnean/zlae169.

Full text

Abstract:

Xuan, Qiang, Prendini, Lorenzo, Engel, Michael S., Cai, Chenyang, Huang, Diying (2025): Extinct scorpion family Chaerilobuthidae from Mid-Cretaceous Burmese amber reinterpreted as subfamily of extant family Pseudochactidae (Chelicerata: Scorpiones). Zoological Journal of the Linnean Society 203 (1): 1-60, DOI: 10.1093/zoolinnean/zlae169, URL: https://doi.org/10.1093/zoolinnean/zlae169

APA, Harvard, Vancouver, ISO, and other styles

42

Zhang, Zhi-Qiang, and Qing-Hai Fan. "Allotanaupodidae, a new family of early derivative Parasitengona (Acari: Prostigmata)." Zootaxa 1517 (December 31, 2007): 1–52. https://doi.org/10.5281/zenodo.177319.

Full text

APA, Harvard, Vancouver, ISO, and other styles

43

Wang, Chuan, Ning Zhang, Xinling Zhang, et al. "Abstract 2927: CS2011: A novel bispecific antibody targeting EGFR and HER3 that demonstrates promising antitumor activity in preclinical evaluation." Cancer Research 85, no. 8_Supplement_1 (2025): 2927. https://doi.org/10.1158/1538-7445.am2025-2927.

Full text

Abstract:

Abstract Background: EGFR (also known as HER1) is an epidermal growth factor receptor with tyrosine kinase activity implicated in both tumorigenesis and tumor progression, and its overexpression in approximately 70% of colorectal cancer (CRC), 60% of lung cancers, and over 90% of head and neck squamous cell carcinoma (HNSCC) have been shown associated with advanced diseases. Approved anti-EGFR therapies, including cetuximab, pantitumumab, and necitumumab, are widely used in treating the aforementioned malignancies. Amivantamab, a bispecific antibody targeting EGFR and c-MET, has been approved

APA, Harvard, Vancouver, ISO, and other styles

44

Gadde, Satyanarayana, Sin Wi Ng, Natalie Chung, et al. "Abstract 6863: Development of MYCN/MYC inhibitors." Cancer Research 85, no. 8_Supplement_1 (2025): 6863. https://doi.org/10.1158/1538-7445.am2025-6863.

Full text

Abstract:

Abstract Background: Deregulated expression of MYC family transcription factors is present in more than 70% of human cancers. MYC is an intrinsically disordered protein without known drug binding pockets and is essential for adult cell replication, making clinical development of MYC inhibitors challenging. MYCN amplification and overexpression generate driver signals in the childhood cancers, neuroblastoma (NB), medulloblastoma (MB) and diffuse intrinsic pontine glioma (DIPG). Methods and Results: We previously reported a small molecule compound, SE486-11, which reduced MYCN protein levels in

APA, Harvard, Vancouver, ISO, and other styles

45

Kaghazchi, Boback, Inigo Lanzagorta Calvillo, Ben King, Enrique Poradosu, Neil O. Carragher, and Asier Unciti-Broceta. "Abstract 5599: NXP900, a novel YES1/SRC kinase inhibitor currently in clinical development, blocks YAP1 signaling in NSCLC cell lines." Cancer Research 85, no. 8_Supplement_1 (2025): 5599. https://doi.org/10.1158/1538-7445.am2025-5599.

Full text

Abstract:

Abstract Background: Most kinase inhibitors exert their anticancer effects by targeting the ATP binding site, either binding and locking an active or inactive kinase conformation, with targeting inactive conformation typically leading to a superior selectivity profile1. NXP900 (eCF506), a highly-potent SRC family kinase (SFK) inhibitor has previously demonstrated high SFK selectivity and the capability to lock the native “closed” conformation (type 1.5), resulting in inhibition of both enzymatic and scaffolding activities2 (IC50 of 0.47 nM against YES1). Conversely, multi-kinase inhibitors das

APA, Harvard, Vancouver, ISO, and other styles

46

Chin, Kar Wei, Connie Wun Chun Hui, Chi-Hang Wong, et al. "Abstract 7338: Evaluation of a novel target Claudin1 in preclinical models of nasopharyngeal carcinoma." Cancer Research 85, no. 8_Supplement_1 (2025): 7338. https://doi.org/10.1158/1538-7445.am2025-7338.

Full text

Abstract:

Abstract Introduction: Epstein-Barr virus (EBV)+ve nasopharyngeal carcinoma (NPC) is prevalent in Southern China where patients with recurrent/ metastatic disease can be treated with chemotherapy and/or immune-checkpoint inhibitors. Claudin 1 (CLDN1) is a member of the tight junction (TJ) family of proteins that is overexpressed in some cancers with their non-junctional (NJ) epitopes exposed at the epithelium. This study investigated CLDN1 as a novel therapeutic target in NPC and evaluated the preclinical activity of ALE.C04 - a first-in-class, highly specific monoclonal antibody targeting NJ-

APA, Harvard, Vancouver, ISO, and other styles

47

Du, Zhuo, Kevin D. Hyde, Qin Yang, Ying-Mei Liang, and Cheng-Ming Tian. "Melansporellaceae: a novel family of Diaporthales (Ascomycota)." Phytotaxa 305, no. 3 (2017): 191–200. https://doi.org/10.11646/phytotaxa.305.3.6.

Full text

Abstract:

Du, Zhuo, Hyde, Kevin D., Yang, Qin, Liang, Ying-Mei, Tian, Cheng-Ming (2017): Melansporellaceae: a novel family of Diaporthales (Ascomycota). Phytotaxa 305 (3): 191-200, DOI: 10.11646/phytotaxa.305.3.6, URL: http://dx.doi.org/10.11646/phytotaxa.305.3.6

APA, Harvard, Vancouver, ISO, and other styles

48

Jin, Zhenyu, Zhao Qin, and Adam Ślipiński. "New records of the family Dascillidae (Coleoptera) from China." Zootaxa 4471, no. 2 (2018): 396–400. https://doi.org/10.11646/zootaxa.4471.2.13.

Full text

APA, Harvard, Vancouver, ISO, and other styles

49

Zhao, Xinzhu. "Confucian Family Education and Ideological Tradition «Tian Di Jun Qin Shi»." RUDN Journal of Philosophy 25, no. 2 (2021): 311–19. http://dx.doi.org/10.22363/2313-2302-2021-25-2-311-319.

Full text

Abstract:

This article will briefly describe the features, methods, goals of family education in ancient China, as well as the relevant educational roles of the father and mother in the family. The article will also analyze one of the most unique characteristics of ancient Chinese family education: in each family fixed a tablet with the words 天地君亲 Tian Di Jun Qin Shi (Heaven, land, rulers, ancestors, sages). In ancient China, people believed that teachers and relatives, and heaven, earth, and monarchs, were objects that people should respect and worship. Obviously, this clearly differs from the traditio

APA, Harvard, Vancouver, ISO, and other styles

50

Tseng, Hung-Fu, Lei Qian, Jun Wu, et al. "19. Completion of Two-Dose Recombinant Zoster Vaccine Series in Adults 50 Years and Older." Open Forum Infectious Diseases 7, Supplement_1 (2020): S32—S33. http://dx.doi.org/10.1093/ofid/ofaa439.064.

Full text

Abstract:

Abstract Background In 2017, the Advisory Committee on Immunization Practices preferentially recommended adjuvanted recombinant zoster vaccine (RZV) for adults ≥ 50 years as a two-dose series 2–6 months apart.1 We evaluated two-dose RZV completion and factors associated with completion. Methods The study included Kaiser Permanente Southern California members ≥ 50 years who received an RZV dose during April-November 2018 and had continuous membership 12 months before to 9 months after the 1st RZV dose (RZV1). Completion was defined as receipt of the 2nd dose ≥4 weeks to 9 months after RZV1 (all

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!