Academic literature on the topic 'QR 75 Bacteria. Cyanobacteria : QH426 Genetics'

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Dissertations / Theses on the topic "QR 75 Bacteria. Cyanobacteria : QH426 Genetics"

1

Lister, Michelle M. "Understanding the genetic mechanisms of Clostridium difficile toxin regulation and clinical relapse." Thesis, University of Nottingham, 2018. http://eprints.nottingham.ac.uk/53216/.

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Clostridium difficile is the leading cause of health care associated diarrhoea and remains a burden for the NHS. Disease symptoms can range from mild diarrhoea through to fulminant pseudomembranous colitis, resulting in mortality for some patients. Recurrence is a major problem and estimates are that 20% of all patients with disease will either relapse (with the same strain) or have a re-infection (with a different strain). Arguably, the main virulence factors are toxins A (TcdA) and toxin B (TcdB) which cause disease symptoms. The genes encoding TcdA and TcdB are located within the pathogenic
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2

Slater, Amy. "Unraveling the regulatory relationship between quorum sensing and the type III secretion system in Yersinia pseudotuberculosis." Thesis, University of Nottingham, 2018. http://eprints.nottingham.ac.uk/51928/.

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Yersinia pseudotuberculosis is a mammalian enteropathogen and is the direct ancestor of Y. pestis, the causative agent of the plague. For its pathogenicity, Y. pseudotuberculosis harbours a 70 kb virulence plasmid which encodes the components of the type three secretion system (T3SS) and effector proteins. These effectors serve to evade the host immune system and induce apoptosis of mammalian cells. Consistent with many Gram-negative bacteria, Yersinia facilitate cell: cell signalling through the production and sensing of N-acylhomoserine lactones (AHLs), which functions to mediate the express
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Piatek, Pawel. "Characterisation of Agr quorum ensing in Clostridium autoethanogenum." Thesis, University of Nottingham, 2018. http://eprints.nottingham.ac.uk/50867/.

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The Gram-positive, anaerobic, acetogenic bacterium Clostridium autoethanogenum is regarded as an important biocatalyst in the current advancement of industrial gas fermentation. The ever-widening diversity of industrially-relevant acetogenic bacteria has inspired a rational approach into utilising industrial waste gases as a viable feedstock, with goals of mitigating greenhouse gas emissions, and supporting an alternative means of fuel and high-value chemical production. Combined with this effort, is the expanding repertoire of gene editing tools that have allowed for the improvement of gas fe
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4

Iwanejko, Lesley Ann. "Cloning the enterotoxin gene from Clostridium perfringens type A." Thesis, University of Nottingham, 1991. http://eprints.nottingham.ac.uk/12195/.

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A C. perfringens type A genomic library was constructed in E. coli by banking overlapping 6-10 kbp Hind III fragments of chromosomal DNA from the enterotoxin (CPE) positive strain NCTC 8239 into the pUC derived vector pHG165. The library was screened by colony hybridization with a degenerate 26 bp oligonucleotide probe, derived from the amino acid sequence CPE9_17A. complex mixture of plasmid DNA was isolated from the only hybridization positive clone. A second round of screening picked out a single plasmid, with an apparently altered copy number, pLWl, that carried the CPE gene, cpe, on a 6.8
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Grosse-Honebrink, Alexander. "Forward and reverse genetics in industrially important Clostridia." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/43549/.

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The bacterial genus Clostridium is composed of Gram-positive, spore-forming rods with widespread biotechnological applications. This study focused mainly on Clostridium pasteurianum DSM 525, a saccharolytic species which is able to convert glycerol, the by-product of the biodiesel industry, into the valuable chemical commodities n-butanol, ethanol and 1,3-propanediol. The aim was to formulate reproducible methods for the creation of mutants, both directed and random, and use the tools developed to investigate genes, and their products, important in solvent production. A prerequisite for the de
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