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1

Vieweg, W. Victor R. "QTc and Metabolic Parameters." Journal of Clinical Psychiatry 67, no. 05 (2006): 838. http://dx.doi.org/10.4088/jcp.v67n0521e.

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2

Aksoy, S. M., S. Cay, G. Cagirci, and N. Sen. "Nebivolol therapy improves QTc and QTcd parameters in heart failure patients." Cardiovascular Journal of Africa 23, no. 4 (2012): 191–93. http://dx.doi.org/10.5830/cvja-2011-046.

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3

Relekar, Rhythm Yogandh, Priyavardhan Mishra, Vishal Raghunath Gabale, Iqra Chandmiya Qureshi, and Vijaykumar Gupta. "Association of QTc prolongation with liver function test and complications in patients with cirrhosis: An observational study." Journal of Family Medicine and Primary Care 14, no. 6 (2025): 2323–29. https://doi.org/10.4103/jfmpc.jfmpc_1814_24.

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ABSTRACT Introduction: Cirrhotic cardiomyopathy is a cardiac abnormality due to hepatic cirrhosis, which presents as a serious electrocardiographic complication and often the patient is asymptomatic. The objective of our study was to find the ECG changes in patients with various aetiologies of cirrhosis and correlate them with their respective LFT parameters. Materials and Methodology: We assessed the QTc interval in patients of various aetiologies of liver cirrhosis and correlated them with the prevalence of complication of cirrhosis, such as portal hypertension, splenomegaly, and ascites. Fu
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Ali, ORGUN, and Demet AKBAŞ Emine. "Evaluation of Ventricular Repolarization Parameters in Obese and Extremely Obese Children." Gevher Nesibe Journal of Medical & Health Sciences 8, Özel Sayısı (2023): 701–7. https://doi.org/10.5281/zenodo.8402874.

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<strong>Aim: </strong>Ventricular arrhythmias are one of the cardiovascular disorders seen in patients with obesity. Electrocardiography (ECG) is a simple and widely used method that enables the evaluation of ventricular depolarization parameters, which are the determinants of ventricular arrhythmias. In this study, we aimed to determine the effect of obesity on ventricular repolarization parameters in children with obesity and compare children who were obese and severely obese. <strong>Material and Methods: </strong>In the study, 86 children with obesity and 84 healthy normal-weight children
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Genç, Ahmet, and Gülsüm Meral Yılmaz Öztekin. "Effect of sacubutril/valsartan on Tp-e, QT, QTc, Tp-e/QTc parameters in heart failure with reduced ejection fraction." Cukurova Medical Journal 49, no. 1 (2024): 47–53. http://dx.doi.org/10.17826/cumj.1377925.

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Purpose: The purpose of this study is to evaluate ventricular repolarization before, at the first month, and sixth month after Sacubutril/Valsartan, an angiotensin receptor neprilysin inhibitor (ARNI) treatment in heart failure patients with reduced ejection fraction (HFrEF).&#x0D; Materials and Methods: We included 49 patients with HFrEF who switched to ARNI therapy. The 12-lead electrocardiography (ECG) was evaluated before ARNI therapy and also during the first and sixth months of the therapy. We evaluated demographic, clinical, and laboratory parameters, as well as medications and ECG data
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Uyar, Seyit, Mehmet Kök, Ayşe Ayan, Muhammet Ali Coşkuner, Gökhan Köker, and Nizameddin Koca. "The evaluation of the short-term and long-term hydroxychloroquine therapy on ECG parameters." Medicine 103, no. 32 (2024): e39039. http://dx.doi.org/10.1097/md.0000000000039039.

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Amidst the COVID-19 pandemic, hydroxychloroquine (HCQ) was widely administered despite limited data on its safety and efficacy. This study assesses the acute and chronic impacts of HCQ on electrocardiography (ECG) parameters alongside the effects of azithromycin and levofloxacin coadministration in patients with COVID-19. A comprehensive analysis was conducted on 109 COVID-19 patients receiving HCQ, with or without Azithromycin and/or Levofloxacin, and 51 long-term HCQ-treated Sjogren’s syndrome (SS) patients. ECG parameters, including QTc interval, were meticulously evaluated against a contro
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Hocagil, Hilal, Abdullah Cüneyt Hocagil, and Tuğba Akkaya Hocagil. "Evaluation of the Risk of Malignant Arrhythmia Through Electrocardiography Parameters in Patients with Urinary Stone Disease." Medical Journal of Western Black Sea 8, no. 2 (2024): 129–34. http://dx.doi.org/10.29058/mjwbs.1397031.

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Introduction: With a lifetime frequency of 10-15% and a recurrence rate of up to 50% within 10 years, urinary stone disease is a major cause of comorbidity. Recently, it has become widely recognized that urinary system stone disease is not only limited to kidney stone development but is also linked to cardiovascular disease and various other illnesses. Malignant arrhythmias (sudden cardiac death and ventricular arrhythmias) are consequences of coronary artery disease. Despite numerous studies demonstrating that urinary system stone disease is a risk factor for coronary artery disease, no elect
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MUHAMMED MUSHTAQ AHMED, ASHOK P YENKANCHI, HABIBULLAH ATTAR, SAIFUDDIN SARGIRO, and SHARHAN PP. "A study on QT dispersion and thrombolytic therapy in acute myocardial infarction." International Journal of Science and Research Archive 13, no. 1 (2024): 2489–795. http://dx.doi.org/10.30574/ijsra.2024.13.1.1968.

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Background: Myocardial infarction is a major manifestation of ischemic heart disease, a leading cause of death in developed nations and the third globally. QTc dispersion is an important marker of ventricular repolarization variations and arrhythmogenic risk. This study examines the effects of thrombolytic therapy on QTc dispersion in acute myocardial infarction Materials and methods: 88 patients admitted to Al Ameen Medical College Hospital, Vijayapur, for acute MI were included in the study. Over a period of 8±2 days, all patients underwent monitoring, with standard 12-lead ECGs conducted up
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9

МУРОМЦЕВА, Г. А., and В. В. КОНСТАНТИНОВ. "Prognostic parameters of the electrocardiogram and electrical heterogeneity of the ventricular myocardium." Kardiologicheskii vestnik, no. 3() (August 24, 2020): 54–59. http://dx.doi.org/10.36396/ms.2020.16.3.007.

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Основываясь на механизмах электрической гетерогенности миокарда желудочков, рассмотрены наиболее вероятные показатели ЭКГ, отраG жающие этот процесс. К их числу относят длительности комплекса QRS, электрической систолы (интервал QT и его корригированные формы, QTc и QTa) интервалы конечной части желудочкового комплекса (QTpa, TpTe), а также угловые характеристики периода реполяризации (углы TpGTref, TinitGTterm) и, главное, желудочковый градиент, пространственный и фронтальный углы QRSGT. В клинических и эпидемиологических исследованиях показаны высокие прогностические возможности этих показат
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10

Wilk-Śledziewska, Katarzyna, Rafał Śledziewski, Małgorzata Gryciuk, et al. "Heart Failure, Kidney Function, and Elderly Age, Rather than Levofloxacin Therapy, Are Associated with QTc Prolongation in COVID-19 Patients." Journal of Clinical Medicine 14, no. 11 (2025): 4006. https://doi.org/10.3390/jcm14114006.

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Background: Prolongation of the QT interval is directly related to the risk of ventricular arrhythmias and sudden cardiac death. Age, comorbidities, and treatment schemes have been shown to influence its prolongation and may also significantly affect the course of SARS-CoV-2 infection. Fluoroquinolones, widely used during the COVID-19 pandemic, are known for their ability to prolong the QT interval. Risk of ventricular arrhythmias has also been reported in patients with infectious diseases, and this risk may have been associated with high levels of interleukin-6 (IL-6). Purpose: The aim of thi
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11

Geçkalan, Damla, Rahmi Özdemir, Yasin Yılmaz, Cemile Hilal Çelik, Batuhan Berk Demir, and Yeşim Tunç. "Can hydroxychloroquine and azithromycin combination cause cardiac rhythm disturbances in children with COVID-19 pneumonia?" Journal of Health Sciences and Medicine 8, no. 2 (2025): 308–12. https://doi.org/10.32322/jhsm.1625339.

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Aims: At the beginning of the COVID-19 pandemic; it has been shown that receiving hydroxychloroquine and azithromycin treatment decrease viral carriage of coronavirus in patients. In this study, we aimed to evaluate electrocardiography (ECG) abnormalities in pediatric patients with COVID-19 pneumonia receiving combined therapy with hydroxychloroquine and azithromycin. Methods: In this study; ECG and laboratory parameters of 24 children with COVID-19 pneumonia who were treated with hydroxychloroquine and azithromycin at Health Sciences University between June 2020 and November 2020 were analyze
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Saramet, Elena E., Robert D. Negru, Andra Oancea, Maria Magdalena Leon Constantin, and Codrina Ancuta. "24 h Holter ECG Monitoring of Patients with Rheumatoid Arthritis—A Potential Role for a Precise Evaluation of QT Interval Duration and Associated Arrhythmic Complications." Diagnostics 12, no. 3 (2022): 638. http://dx.doi.org/10.3390/diagnostics12030638.

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Background: Patients with rheumatoid arthritis (RA) have increased systemic inflammatory burden associated with elevated cardiovascular mortality. Prolonged ventricular repolarisation evaluated by QT interval duration is a risk factor for cardiovascular and total mortality. In RA, mortality risk is correlated with dynamics and cumulative incidence of QTc prolongation rather than QTc value. The aim is to evaluate if QT parameters evaluated with 24 h Holter ECG are a better option to complete the cardiovascular profile of RA patients than parameters from short ECG recordings. Materials and metho
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13

Candas, Fatih, Zafer Isilak, Akin Yildizhan, et al. "Does endoscopic thoracic sympathectomy through clipping procedure have early effects on electrocardiographic parameters?" Indian Journal of Medical Research 145, no. 4 (2017): 498–502. https://doi.org/10.4103/ijmr.ijmr_1133_14.

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Background &amp; objectives: Hyperhidrosis is a pathologic condition of excessive sweating in amounts greater than physiologic needs. Endoscopic thoracic sympathectomy (ETS) is a globally accepted treatment modality for primary palmar and axillary hyperhidrosis. ETS also has distinctive effects on the heart, circulatory and respiratory systems. In this study early effects of ETS on electrocardiographic (ECG) parameters of hyperhidrosis patients were evaluated. Methods: Twelve-lead ECGs were performed on 72 patients who were free from cardiovascular, metabolic, neurological and pulmonary diseas
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14

Thiruvenkatarajan, Venkatesan, Jenn Yuan Lee, Manesha Sembu, Richard Watts, and Roelof Markus Van Wijk. "Effects of esmolol on QTc interval changes during tracheal intubation: a systematic review." BMJ Open 9, no. 4 (2019): e028111. http://dx.doi.org/10.1136/bmjopen-2018-028111.

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Introduction and aimsEsmolol is an ultra-short-acting β1 antagonist that has been shown to attenuate the corrected QT (QTc) interval prolongation associated with laryngoscopy and endotracheal intubation (LTI). Prolongation of the QTc interval can precipitate arrhythmias, the most serious of which is torsades de pointes . The aim of this systematic review was to compare esmolol and placebo on QTc changes occurring during LTI.Materials and methodsPubMed, EMBASE, Cochrane Registry of Clinical Trials and CINAHL databases (up to August 2018) were screened for randomised controlled trials comparing
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15

ÇETİNKAYA, Zeki, Şaban KELEŞOĞLU, Ferhat GÖKAY, and Yücel YILMAZ. "Evaluation of Tp-e interval, Tp-e/QT, and Tp-e/QTc ratio in primary hyperparathyroidism before and after parathyroidectomy." Anatolian Current Medical Journal 6, no. 1 (2024): 73–79. http://dx.doi.org/10.38053/acmj.1382439.

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Aims: This study aimed to evaluate Tp-e interval, Tp-e/QT ratio, and Tp-e/QTc ratios, which are new ventricular repolarization (VR) parameters in primary hyperparathyroidism (PHPT) patients, and also investigate the potential effect of parathyroidectomy (PTx) on these parameters. Methods: In total, 27 patients with PHPT who underwent PTx and 25 control subjects were selected for our study. Tp-e interval, Tp-e/QT ratio, and Tp-e/QTc ratios of patients planned for PTx were compared to healthy matched controls. Electrocardiographic parameters measured 6 months after the surgery were also compared
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16

Sharif, Saleh, Eran Kalmanovich, Gil Marcus, et al. "QTc Prolongation as a Diagnostic Clue in Acute Pulmonary Embolism." Journal of Clinical Medicine 14, no. 14 (2025): 5005. https://doi.org/10.3390/jcm14145005.

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Background: Pulmonary embolism (PE) increases right ventricular (RV) afterload, potentially leading to myocardial stress and electrocardiographic abnormalities. Although QTc prolongation has been suggested as a marker of RV dysfunction, its prevalence, clinical significance, and prognostic value in acute PE remain poorly defined. Objective: The objective of this study is to evaluate the prevalence and clinical implications of QTc prolongation in patients with intermediate–high and high-risk acute PE. Methods: We retrospectively analyzed 95 consecutive patients admitted with intermediate–high o
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Sahin, Kader Eliz, Mesut Karatas, Sezgin Barutcu, and Ibrahim Halil Inanc. "Evaluation of the Electrocardiographic Tp-e, Tp-e/QT, and Tp-e/QTc Parameters in Patients with Non-Alcoholic Liver Disease." Medicina 61, no. 4 (2025): 766. https://doi.org/10.3390/medicina61040766.

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Background and Objectives: Non-alcoholic fatty liver disease (NAFLD) is a common chronic liver disease associated with significant morbidity, including cardiovascular complications. This study investigates the relationship between NAFLD and electrocardiographic parameters indicative of ventricular arrhythmia risk. Materials and Methods: We conducted a cross-sectional study enrolling 136 patients with NAFLD and 136 healthy controls. Electrocardiographic parameters—Tp-e interval, QT and corrected QT (QTc) intervals, and Tp-e/QTc ratio—were measured and compared between groups. Results: Patients
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18

Msayer, Kawthar H. "QT interval analysis in type 2 diabetic patients." Journal of the Faculty of Medicine Baghdad 52, no. 4 (2011): 262–467. http://dx.doi.org/10.32007/jfacmedbagdad.524958.

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Background: The electrocardiographic QT interval has been extensively studied in diabetes mellitus. Recently, there has been increasing interest in the relationship between diabetes and QT abnormalities .The QT interval, which is easily obtained from a standard resting electrocardiogram( ECG), reflected the total duration of ventricular myocardial depolarization and repolarization. The heart rate corrected QT interval (QTc) by Bazett's formula on the electrocardiogram has been proposed as a risk factor for ventricular arrhythmias in diabetes mellitus. Dispersion of QT(QTd) is defined as the di
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19

Kolo, P. "Psychotropic Medications and QTc Parameters in a Nigerian Cohort." British Journal of Medicine and Medical Research 2, no. 3 (2012): 434–43. http://dx.doi.org/10.9734/bjmmr/2012/1264.

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20

Gülkesen, Arif, Emine Yıldırım Uslu, Gürkan Akgöl, et al. "Is the development of arrhythmia predictable in rheumatoid arthritis?" Archives of Rheumatology 39, no. 3 (2024): 429–35. http://dx.doi.org/10.46497/archrheumatol.2024.10590.

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Objectives: This study aimed to determine whether there is a difference in the electrocardiography (ECG) measurements of healthy controls and rheumatoid arthritis (RA) patients and to predict whether they can be used to determine the risk of arrhythmia in patients. Patients and methods: The prospective study included 50 cardiac asymptomatic RA patients (38 males, 12 females; mean age: 46.8±9.1 years; range, 18 to 60 years) who met the 2010 American College of Rheumatology/European Alliance of Associations for Rheumatology RA criteria and 50 healthy volunteers (34 males, 16 females; mean age: 4
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Priya C. Rao, Chethan H.A. "Study of Changes in QTc Interval with Menstrual Cycle in Young Adult Female Basket Ball Players." International Journal of Physiology 7, no. 4 (2019): 165–66. http://dx.doi.org/10.37506/ijop.v7i4.82.

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Objective&#x0D; Study of changes in QTc interval with menstrual cycle in young adult female basketball players.&#x0D; Method&#x0D; Healthy young female adults in the age group of 18–22 years physicaly fit subjects were selected among general population. Sample size was 40. Parameters of ECG, QT interval, RR interval, QTc Interval were recorded during different phases of menstrual cycle. Mean and Standard deviation was calculated.&#x0D; Results&#x0D; There was significant rise in QTc Interval recorded during menstrual phase&#x0D; Conclusion&#x0D; Women are at risk of developing ventricular arrh
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Yadav, Shree Narayan Yadav, Mani Prasad Gautam, Pushpa Adhikari, Sunil Ram Koirala, and Duryodhan Yadav. "A Study on QTc Prolongation as An Indicator of Cardiac Autonomic Neuropathy in Diabetic Patients at Bir Hospital, Nepal." International Journal of Silkroad Institute of Research and Training 2, no. 2 (2024): 85–91. https://doi.org/10.3126/ijsirt.v2i2.72064.

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Background: Diabetes mellitus frequently leads to cardiac autonomic neuropathy (CAN), a complication that disrupts heart rate control and vascular function, increasing the risk of silent myocardial ischemia and sudden cardiac death. Prolonged QTc interval on ECG has emerged as a reliable marker for detecting CAN. Methods: A cross-sectional study was conducted on 100 diabetic patients at NAMS, Bir Hospital, Nepal, from September 2021 to June 2022. Data on QTc intervals and other clinical parameters were analyzed using STATA 13.0 software. Results: Among the 100 patients, 60% were diagnosed with
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23

Komolyatova, V. N., L. M. Makarov, I. I. Kiseleva, et al. "Changing QT interval in orthostasis — new diagnostic marker of syndrome of extended QT interval." Medical alphabet 2, no. 21 (2019): 18–21. http://dx.doi.org/10.33667/2078-5631-2019-2-21(396)-18-21.

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Long QT interval syndrome (LQTS) is a disease that causes life-threatening arrhythmias and sudden death syndrome. Recently, it has been shown that about half of patients with LQTS have normal QTc interval values on an ECG. The purpose of this study was to assess changes in the QT interval in patients with LQTS in orthostasis to identify additional criteria for the disease. Surveyed 64 patients from 4 to 47 years old (13.3 ± 10.0) with LQTIS. The control group consisted of 87 healthy people of 4–20 years (11.0 ± 3.5). An ECG was performed in a lying and standing position. HR, QT and QTc interrv
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Janakiraman, Sathiyanarayanan, Ramesh Bala Arivazhagan, and Manokaran Chinnusamy. "Prevalence of QTc prolongation among hypertensive patients and its association with other co-morbidities." International Journal of Advances in Medicine 9, no. 3 (2022): 300. http://dx.doi.org/10.18203/2349-3933.ijam20220434.

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Background: Hypertension, an iceberg disease contributes significantly to the global health burden. This pan-endemic disease is a harbinger for cardiovascular events, especially life-threatening arrhythmias. A simple and cost-effective electrocardiogram serves as an effective tool to identify and evaluate hypertensives with high cardiovascular risk. QTc interval which indicates repolarization abnormality is one such effective tool. The study aimed at describing the prevalence of QTc prolongation among hypertensive individuals and also to assess the association of QTc prolongation with various
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Genkel, V. V., V. N. Pospelov, A. S. Kuznetsova, et al. "Duration and dispersion of QT interval in patients with liver cirrhosis: diagnostic and prognostic value." Сибирский научный медицинский журнал 45, no. 1 (2025): 139–47. https://doi.org/10.18699/ssmj20250115.

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The data on the prognostic significance and relationship of the prolonged QT syndrome with the risk of cardiac rhythm disturbances in liver cirrhosis are contradictory. One of the directions of further research in this area is to study the significance of other electrocardiographic parameters reflecting ventricular repolarization disturbance in patients with liver cirrhosis. Aim of the study was to investigate diagnostic and prognostic value of electrocardiographic parameters reflecting changes in heart electrical systole and heterogeneity of ventricular repolarization in relation to the prese
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Bienias, Piotr, Michał Ciurzyński, Bartłomiej Kisiel, et al. "Influence of disease severity and cardiac autonomic tone on ventricular repolarization and dispersion in electrocardiographic assessment of patients with systemic lupus erythematosus." Lupus 29, no. 8 (2020): 913–23. http://dx.doi.org/10.1177/0961203320928402.

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Background There are no data on the influence of disease severity and cardiac autonomic tone on ventricular repolarization and dispersion in 24-hour Holter monitoring in systemic lupus erythematosus (SLE). Methods Consecutive 92 SLE and 51 healthy subjects were studied. The standard 12-lead electrocardiography (ECG), Holter monitoring with heart rate turbulence (HRT) and QT, Tp-e and Tp-e/QT ratio assessment (including corrected values) were performed. Subjects with conditions causing repolarization abnormalities or insufficient number of beats suitable for QT evaluation were excluded (17 SLE
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Hlaing, Zarchi Theint Theint, Soe Minn Htway, and Mya Thanda Sein. "Relationship between Corrected QT Interval (QTc) Prolongation and Insulin Resistance in Obese Adult Male Subjects." European Journal of Medical and Health Sciences 3, no. 1 (2021): 42–45. http://dx.doi.org/10.24018/ejmed.2021.3.1.655.

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QT Interval prolongation is common in insulin resistance state obesity. Insulin-induced hyperpolarization might be involved in ventricular repolarization leading to QTc lengthening. Therefore, this study is designated to investigate the relationship between corrected QT interval (QTc) prolongation and insulin resistance in obese adult male subjects. Apparently healthy adult male subjects (n=100) aged between 18-35 years residing in Magway Township were recruited by simple random sampling method. Then all the eligible subjects were categorized into 2 groups: non-obese [body mass index (BMI) 18.
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Suna, Normunds, Inga Suna, Evija Gutmane, et al. "Electrocardiographic Abnormalities and Mortality in Epilepsy Patients." Medicina 57, no. 5 (2021): 504. http://dx.doi.org/10.3390/medicina57050504.

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Background and Objectives: People with epilepsy (PWE) have a 2–3 times higher mortality rate than the general population. Sudden unexpected death in epilepsy (SUDEP) comprises a significant proportion of premature deaths, whereas sudden cardiac death (SCD) is among the leading causes of sudden death in the general population. Cardiac pathologies are significantly more prevalent in PWE. Whether electrocardiographic (ECG) parameters are associated with remote death in PWE has yet to be elucidated. The study objective was to assess whether interictal ECG parameters are associated with mortality i
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Gawali, Pandharinath S., Sachin N. Solanke, and Sudhir L. Tungikar. "Prevalence of prolonged corrected QT interval and its impact on outcomes in patients admitted in medical intensive care unit." International Journal of Advances in Medicine 5, no. 5 (2018): 1116. http://dx.doi.org/10.18203/2349-3933.ijam20183856.

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Background: The long QT syndrome (LQTS) is a disorder of myocardial repolarization characterized by a prolonged QT interval on the electrocardiogram (ECG). Hence the present study was aimed to determine prevalence of QT prolongation of the ECG and to assess its impact on outcomes in patients admitted in medical ICU of Noor Hospital of IIMSR Medical College, Badnapur, Jalna, Maharashtra, India.Methods: This prospective observational study was carried out during the period of October 2016 to March 2018, for assessment of prevalence of prolonged QTc at admission and its impact on outcomes in medi
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Putri, Sheila Dhiene, Harris Hasan, Refli Hasan, A. Afif Siregar, Nizam Akbar, and Cut Aryfa Andra. "Significance of Electrocardiographic QTc Interval on Assessment of Left Ventricular Diastolic Dysfunction in Hypertensive Patient: A Simple Screening Tool." ACI (Acta Cardiologia Indonesiana) 5, no. 1 (2019): 44. http://dx.doi.org/10.22146/aci.44551.

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Background: Diastolic dysfunction as part of heart failure with preserved ejection fraction (HFpEF) has gain interests, due to the increasing prevalence rate and poor prognosis. Besides the mechanism is not fully understood, there are some difficulties in detecting the presence of diastolic dysfunction. Previous studies have shown correlation between some electrocardiographic parameters and diastolic function. Furthermore, the aim of this study is to assess the diagnostic value of the QTc interval in detecting left ventricular diastolic dysfunction.Methods: A cross sectional study was conducte
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Al Alwany, Ameen Abdulhasan. "Effect and benefit of percutaneous coronary intervention in chronic total occlusion on ventricular repolarization: QT correction and dispersion." Journal of Medicine and Life 15, no. 8 (2022): 1025–30. http://dx.doi.org/10.25122/jml-2022-0207.

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ST segment, T wave changes, QT interval changes, and QTc dispersion are among the parameters used to diagnose ischemic heart disease. The increase in the QT dispersion can be caused by myocardial ischemia, among other heart diseases, whereas cardiac diseases such as coronary artery disease (CAD) can be diagnosed by observing an abnormally high QTc dispersion. This study aimed to evaluate the variations in the QTc dispersion (depolarization and repolarization) of surface electrocardiography as a result of percutaneous coronary intervention (PCI) in patients with chronic total occlusion. This st
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Sökmen, Erdoğan, Hacı Mehmet Çalışkan, Mustafa Çelik, Serkan Sivri, Yalçın Boduroğlu, and Sinan Cemgil Özbek. "The Effect of Lower and Higher Calorie Meal on the Parameters of Ventricular Repolarization in Healthy Subjects." Open Access Macedonian Journal of Medical Sciences 7, no. 3 (2019): 329–35. http://dx.doi.org/10.3889/oamjms.2019.084.

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BACKGROUND: Cardiovascular modulation following meal consumption has been known. Little and conflicting data is present regarding electrocardiographic QT and QTc intervals after a meal, and status of ventricular repolarization following meal is not known comprehensively.&#x0D; AIM: To inquire the electrocardiographic status of ventricular repolarisation thoroughly after lower and higher calorie meal consumption in a comparative manner.&#x0D; METHODS: A group of 61 healthy individuals were studied before and after lunch. They were divided into two groups according to the calorie consumed (highe
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Mulia, Eka Prasetya Budi, Kartika Afrida Fauzia, and Rerdin Julario. "High risk of ventricular repolarization abnormalities among hemodialytic end-stage renal disease patients." Folia Medica 64, no. 6 (2022): 905–12. http://dx.doi.org/10.3897/folmed.64.e68349.

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Introduction: Patients with chronic renal disease (CKD) are at a significantly elevated risk for ventricular arrhythmia. Several electrocardiographic (ECG) methods can be used to assess the ventricular arrhythmia risk on the standard 12-lead ECG. Aim: This study aimed to evaluate the ECG parameters of ventricular repolarization abnormalities, such as QT, QTc, Tp-e, and Tp-e/QT ratio, Tp-e/QTc ratio, and their predictors in hemodialytic end-stage renal disease (ESRD) patients. Materials and methods: Fifty-three patients with hemodialytic ESRD and 32 pre-dialytic CKD patients were enrolled in th
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Yesil, Emrah, Hakan Uyar, Ozcan Orscelik, et al. "The effect of ferric carboxymaltose treatment on the Tp-e interval and the Tp-e/QT and Tp-e/QTc ratios in heart failure patients with iron deficiency." Kardiologiia 62, no. 10 (2022): 42–48. http://dx.doi.org/10.18087/cardio.2022.10.n2211.

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Aim In heart failure (HF) patients with iron deficiency, cardiac electrical irregularity is a cause of arrhythmias. The aim of our study was to evaluate the effect of ferric carboxymaltose (FCM) treatment on T wave peak to end (Tp-e) interval and the Tp-e / QT and Tp-e / corrected QT (QTc) ratios that reflect the transmural dispersion of repolarization in HF patients with iron deficiency.Material and methods Forty HF patients with iron deficiency that were treated with FCM were included in our single center, observational study. Repolarization parameters on electrocardiograms recorded before a
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Coskun, Abuzer, Burak Demirci, Mehmet Oktay Alkan, Selman Gundogan, and Sevki Hakan Eren. "The Prognostic Significance of QTc Prolongation in Lead aVR in Patients with Acute Coronary Syndrome with ST Elevation or Depression." Medicina 60, no. 12 (2024): 2038. https://doi.org/10.3390/medicina60122038.

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Background and Objectives: In patients with acute coronary syndrome, electrocardiographic parameters, including ST elevation in lead aVR (aVR-STE), ST depression (aVR-STD), and QTc prolongation, are crucial. This study aims to show the predictive value of a longer QTc in emergency department patients with acute coronary syndrome and ≥1 mm ST elevation or depression in the aVR lead in electrocardiography. Materials and Methods: A retrospective analysis was conducted on 1273 patients admitted to the emergency department with a preliminary diagnosis of acute coronary syndrome between 2020 and 202
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Lu, Yaxin, Nathan Ussher, Yuling Zhou, et al. "Matrix Metalloproteinase-3 (MMP-3) Polymorphisms Are Associated with Prolonged ECG-Derived QTc Interval: A Cross-Sectional Study of the Australian Rural Population." Journal of Personalized Medicine 11, no. 8 (2021): 705. http://dx.doi.org/10.3390/jpm11080705.

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Matrix metalloproteinases (MMPs) are enzymes that are integral in extracellular matrix (ECM) remodeling. In age or disease, ECM may become dysregulated and contribute to fibrosis, which impairs cardiac electrical conduction. Two alleles regulate matrix metalloproteinase-3 (MMP-3) activity: one with five adenosine bases (5A; associated with higher MMP-3 activity and decreased fibrosis) and another with six adenosine bases (6A; associated with lower MMP-3 activity and increased fibrosis). Here, we determined whether ECG-derived QTc and related parameters are associated with the MMP-3 5A/6A genot
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Taşbulak, Ömer, Ahmet Anıl Şahin, and Serkan Kahraman. "Impact of cardiac rehabilitation on ventricular repolarization indices following coronary artery bypass grafting." Turkish Journal of Thoracic and Cardiovascular Surgery 29, no. 2 (2021): 143–49. http://dx.doi.org/10.5606/tgkdc.dergisi.2021.20736.

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Background: The aim of this study was to evaluate the effect of cardiac rehabilitation on electrocardiographic changes in patients undergoing isolated coronary artery bypass grafting. Methods: Between January 2016 and July 2019, a total of 625 patients (485 males, 140 females; mean age: 59.6 years; range, 50.6 to 68.6 years) who underwent isolated coronary artery bypass grafting and survived were retrospectively analyzed. The patients were divided into two groups according to the participation in the cardiac rehabilitation program as follows: the Rehab(+) group (n=363) and the Rehab(-) group (
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Yükcü, Bekir, Bedia Sultan Önal, Cansu Çobanoğlu Osmanlı, Gülsüm Yitik Tonkaz, and Berkan Şahin. "Cardiological Findings in Children and Adolescents Before and After Guanfacine Treatment for Attention Deficit and Hyperactivity Disorder." Children 12, no. 3 (2025): 302. https://doi.org/10.3390/children12030302.

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Objective: This study evaluates the short-term cardiovascular effects of guanfacine treatment in children and adolescents with attention deficit/hyperactivity disorder (ADHD). The treatment’s impact on novel electrocardiographic parameters was also investigated. Methods: In a retrospective study conducted between January 2023 and June 2024, 37 patients aged 6–18 years with ADHD underwent baseline and follow-up cardiac evaluations including electrocardiography (ECG) and blood pressure measurements. Novel ECG markers (QRS-T angle, QT dispersion, QTc dispersion, Tp-e interval, Tp-e dispersion, Tp
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Dr., Hamna Sohail Dr. Usman Ghani Dr. Junaid Babar. "DIABETIC DISORDERS ASSOCIATION WITH ARRHYTHMIA & SUDDEN CARDIAC DEATH IN THE LIGHT OF ELECTROCARDIOGRAPHIC AND LABORATORY OUTCOMES." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 07 (2018): 7050–56. https://doi.org/10.5281/zenodo.1325895.

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<strong><em>Objectives: </em></strong>&nbsp;<em>Arrhythmia and unexpected cardiac death risk is increased in cardiac microvascular circulation and diabetic disorders. T p-e dispersion, T peak &ndash; T end (T p-e) interval &amp; (T p-e / QT) &amp; (T p-e / QTc) proportions which are measured through ECG (Electrocardiogram) are relatively new parameters for ventricular arrhythmogenesis evaluation. Our research was aimed on the comparison of QT dispersion (QTcd) corrected, QT (QTd) dispersion, T p-e interval, P dispersion (Pd), (T p-e / QT) &amp; (T p-e / QTc) proportions and T p-e dispersion in
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40

Dr., Hamna Sohail Dr. Usman Ghani Dr. Junaid Babar. "DIABETIC DISORDERS ASSOCIATION WITH ARRHYTHMIA & SUDDEN CARDIAC DEATH IN THE LIGHT OF ELECTROCARDIOGRAPHIC AND LABORATORY OUTCOMES." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 07 (2018): 7097–103. https://doi.org/10.5281/zenodo.1325912.

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<strong><em>Objectives: </em></strong>&nbsp;<em>Arrhythmia and unexpected cardiac death risk is increased in cardiac microvascular circulation and diabetic disorders. T p-e dispersion, T peak &ndash; T end (T p-e) interval &amp; (T p-e / QT) &amp; (T p-e / QTc) proportions which are measured through ECG (Electrocardiogram) are relatively new parameters for ventricular arrhythmogenesis evaluation. Our research was aimed on the comparison of QT dispersion (QTcd) corrected, QT (QTd) dispersion, T p-e interval, P dispersion (Pd), (T p-e / QT) &amp; (T p-e / QTc) proportions and T p-e dispersion in
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41

Elifoğlu, İlknur, Rahmi Özdemir, Veysel Nijat Baş, Damla Geçkalan, and Emine Değirmen Şişman. "Evaluation of cardiac repolarization inhomogeneity in children with type 1 diabetes mellitus." Trends in Pediatrics 6, no. 2 (2025): 102–7. https://doi.org/10.59213/tp.2025.198.

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Objective: Type 1 diabetes mellitus is the most common endocrine-metabolic disease in childhood, which progresses with insulin deficiency and can cause serious cardiovascular complications. Atrial and ventricular arrhythmias are important cardiovascular complications of diabetes. In this study, cardiac repolarization inhomogeneity in children with Type 1 diabetes mellitus was evaluated electrocardiographically. Method: Between February 2021 and April 2021, 48 patients with Type 1 diabetes mellitus and an equal number of healthy control groups were included in the study. Demographic characteris
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Verdugo-Marchese, Mario, Stefano Coiro, Christine Selton-Suty, et al. "Left ventricular myocardial deformation pattern, mechanical dispersion, and their relation with electrocardiogram markers in the large population-based STANISLAS cohort: insights into electromechanical coupling." European Heart Journal - Cardiovascular Imaging 21, no. 11 (2020): 1237–45. http://dx.doi.org/10.1093/ehjci/jeaa148.

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Abstract Aims Mechanical alterations in patients with electrical conduction abnormalities are reported to have prognostic value in patients with left ventricular asynchrony or long QT syndrome beyond electrocardiogram (ECG) variables. Whether conduction and repolarization patterns derived from ECG are associated with speckle tracking echocardiography parameters in subjects without overt cardiac disease is yet to be investigated. To report ranges of longitudinal deformation according to conduction and repolarization values in a population-based cohort. Methods and results One thousand, one hund
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Cuenca-Bermejo, Lorena, María Josefa Fernández-Del Palacio, Valeria de Cassia Gonçalves, et al. "Age and Sex Determine Electrocardiogram Parameters in the Octodon degus." Biology 12, no. 5 (2023): 747. http://dx.doi.org/10.3390/biology12050747.

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Cardiovascular diseases represent the leading cause of mortality and morbidity worldwide, and age is an important risk factor. Preclinical models provide supportive evidence toward age-related cardiac changes, as well as allow for the study of pathological aspects of the disease. In the present work, we evaluated the electrocardiogram (ECG) recording in the O. degus during the aging process in both females and males. Taking into account the age and sex, our study provides the normal ranges for the heart rate, duration and voltage of the ECG waves and intervals, as well as electrical axis devia
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Olufemi, Owolade Samuel, Aderibigbe Olaide Ruth, Mustapha Balikis Oluwakemi, Ademoyegun Temitope Olufemi, and Adeoye Iyabo Bosede. "Quality evaluation, consumer acceptability, and cost-benefit analysis of mango-plus beverage." International Journal of Sustainable Agricultural Research 11, no. 4 (2024): 190–202. https://doi.org/10.18488/ijsar.v11i4.4012.

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This study aims to produce a mango-plus beverage from a blend of mango and pineapple fruits and its market prospects determined. Mango and pineapple were processed into beverages at different ratios (1:0, 1:1, 1:2, and 1:3) and coded as FKJ, WTC, PMG, and QTC, respectively. Parameters that include proximate, TSS, pH, vitamin C, total phenol, sensory characteristics, microbial load, and cost-benefit analysis were determined. Findings show significant differences existed among the sample's parameters at p&lt;0.05. Sample QTC, which was a mango-pineapple blend (1:3), gave the highest ash content
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Gervais, Anne-Sophie, Adrien Flahault, Chan Tevy, et al. "97 Electrocardiographic features at rest and during exercise in young adults born preterm below 30 weeks of gestation." Paediatrics & Child Health 25, Supplement_2 (2020): e40-e41. http://dx.doi.org/10.1093/pch/pxaa068.096.

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Abstract Introduction/Background Preterm birth has adverse consequences on the cardiovascular system. Whether premature birth is associated with conduction and repolarisation abnormalities past childhood and into adulthood still needs to be demonstrated. An exercise test could reveal such abnormalities. Objectives We aimed to assess electrocardiographic changes, particularly corrected QT (QTc) prolongation, in a cohort of young adults born preterm, at rest and during exercise. Design/Methods We analysed the ECG of young adults (23.9±3.1 years) born term (≥37 weeks, n=53) and preterm (&amp;lt;3
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Tselik, N. Ye, and O. V. Bilchenko. "Factors of QTc interval prolongation in patients with arterial hypertension." Zaporozhye Medical Journal 25, no. 1 (2023): 5–10. http://dx.doi.org/10.14739/2310-1210.2023.1.262450.

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The relevance of determining the factors of the prolonged QTc interval development in patients with arterial hypertension is high, as it solves the issue of preliminary diagnosis among patients from risk groups and allows adjusting the diagnostic and therapeutic tactics of managing such patients. Aim: to determine factors for the development of prolonged average daily QTc interval in patients with arterial hypertension. Materials and methods. The study included 195 patients with arterial hypertension, who were divided into 2 subgroups: 175 individuals with a normal average daily duration of th
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Kolo, P.M., P.O. Ajiboye, A.D. Yusuf, A.B. Omotoso, and E.O. Okoro. "Psychotropic Medications and QTc Parameters in a Nigerian Cohort." June 25, 2012. https://doi.org/10.5281/zenodo.7838.

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Aims: Evidence is increasing to indicate that individuals with mental illness may be at risk of premature death. We studied the prevalence of QTc prolongation, QT dispersion (QTd) and cardiac arrhythmias in patients on psychotropic drugs. Study Design: Cross-sectional study. Place and Duration of Study: Department of Medicine and Department of Behavioral Sciences, University of Ilorin Teaching Hospital, Nigeria Between Januaryand June 2010. Methodology: One hundred and ninety-one consecutive patients on psychotropic medications with 121 controls were studied. All the subjects had detailed clin
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Yildiz, S. S., N. Sutasir, S. Sigirci, H. Topcu, and K. Kilickesmez. "P2544Acute effects of synthetic cannabinoids on ventricular repolarization parameters." European Heart Journal 40, Supplement_1 (2019). http://dx.doi.org/10.1093/eurheartj/ehz748.0872.

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Abstract Bacground The association between ventricular repolarization parameters (VRP) and ventricular arrhythmias has been shown in previous studies. However, there are limited data on the association between synthetic cannabinoids (SCs) and VRP. Purpose To analysis the acute effects of SCs on VRP by using T-peak to T-end (Tp-e) interval, Tp-e/QT ratio and Tp-e/QTc ratio. Methods The present study included 58 patients who admitted to the emergency department and who used of SC (SC+) during the years 2014–2016, and 50 healthy control subjects (SC−). QT and QTc intervals, Tp-e interval, Tp-e/QT
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EREN, Hayati, Selin GENÇ, Bahri EVREN, and İbrahim ŞAHİN. "Evaluation of novel ventricular repolarization parameters in patients with acromegaly." European Research Journal, March 21, 2023, 1–9. http://dx.doi.org/10.18621/eurj.1128668.

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Objectives: T wave’s peak and end interval (Tp-e), Tp-e/QT ratio and Tp-e/QTc ratio are novel markers of ventricular repolarization and are associated with ventricular arrhythmias. Increased ventricular arrhythmia incidence is reported in patients with acromegaly. The purpose of this study is to evaluate ventricular repolarization using the Tp-e interval, Tp-e/QT ratio, and Tp-e/QTc ratio in patients with acromegaly. Methods: Thirty-five patients with acromegaly were included in the study. The control group was consisted of forty-one subjects without acromegaly that having similar age, sex rat
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Hassan, Khaled. "ECG INTERPRETATION AMONG COVID-19 PATIENTS." International Journal of Medical and Biomedical Studies 5, no. 8 (2021). http://dx.doi.org/10.32553/ijmbs.v5i8.2060.

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Background: The goal was to use surface electrocardiographic (ECG) indicators to detect COVID-19's malignant arrhythmic potential.&#x0D; Methodology: In 51 COVID-19 patients and 40 control subjects, the ECG parameters PR, QT, QTc, QTd, TPe, and Tpe/QTc were assessed. COVID-19 patients had substantially higher mean QTc (410.8 24.3 msec vs. 394.6 20.3 msec, p.001), Tpe/QTc (0.19 0.02 vs. 0.18 0.04, p =.036), and median QTd (47.52 vs. 46.5) values than the control group. Troponin levels were linked with heart rate (r = 0.387, p =.006) but not with ECG parameters (r = 0.387, p =.006).&#x0D; Conclu
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