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Journal articles on the topic 'Quad-stage method'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Qi, Jiexing, Chang Su, Zhixin Guo, et al. "Enhancing SPARQL Query Generation for Knowledge Base Question Answering Systems by Learning to Correct Triplets." Applied Sciences 14, no. 4 (2024): 1521. http://dx.doi.org/10.3390/app14041521.

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Generating SPARQL queries from natural language questions is challenging in Knowledge Base Question Answering (KBQA) systems. The current state-of-the-art models heavily rely on fine-tuning pretrained models such as T5. However, these methods still encounter critical issues such as triple-flip errors (e.g., (subject, relation, object) is predicted as (object, relation, subject)). To address this limitation, we introduce TSET (Triplet Structure Enhanced T5), a model with a novel pretraining stage positioned between the initial T5 pretraining and the fine-tuning for the Text-to-SPARQL task. In t

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Ghawadri, Nizam, Norazak Senu, Firas Fawzi, Fudziah Ismail, and Zarina Ibrahim. "Explicit Integrator of Runge-Kutta Type for Direct Solution of u(4)=f(x,u,u′,u′′)." Symmetry 11, no. 2 (2019): 246. http://dx.doi.org/10.3390/sym11020246.

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The primary contribution of this work is to develop direct processes of explicit Runge-Kutta type (RKT) as solutions for any fourth-order ordinary differential equation (ODEs) of the structure u ( 4 ) = f ( x , u , u ′ , u ′ ′ ) and denoted as RKTF method. We presented the associated B-series and quad-colored tree theory with the aim of deriving the prerequisites of the said order. Depending on the order conditions, the method with algebraic order four with a three-stage and order five with a four-stage denoted as RKTF4 and RKTF5 are discussed, respectively. Numerical outcomes are offered to i

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Menon, Preetha, Mohamed El-Sadig, Marwan F. Albastaki, et al. "Collecting behavioral evidence from a highly mobile and seasonal population: A protocol for a survey on quad bike injuries." PLOS ONE 19, no. 3 (2024): e0298059. http://dx.doi.org/10.1371/journal.pone.0298059.

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Background Quad bikes are popular recreational, four-wheeled bikes in the Middle East. Injury prevention programs targeting quad bike crashes in the United Arab Emirates (UAE) need evidence about the risk factors and behaviours associated with these crashes in the target population. This is a protocol for a study aiming to investigate quad bike rider behaviours and to assess the risk factors associated with related injuries in the UAE. Methods This is a cross-sectional observational study aiming to describe a seasonal sport in a desert environment. With an estimated sample size of 451, the sur

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Luan, Zhong, Hao Zeng, Yuanyuan Shang, Zhuhong Shao, and Hui Ding. "Fast Video Dehazing Using Per-Pixel Minimum Adjustment." Mathematical Problems in Engineering 2018 (2018): 1–8. http://dx.doi.org/10.1155/2018/9241629.

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To reduce the computational complexity and maintain the effect of video dehazing, a fast and accurate video dehazing method is presented. The preliminary transmission map is estimated by the minimum channel of each pixel. An adjustment parameter is designed to fix the transmission map to reduce color distortion in the sky area. We propose a new quad-tree method to estimate the atmospheric light. In video dehazing stage, we keep the atmospheric light unchanged in the same scene by a simple but efficient parameter, which describes the similarity of the interframe image content. By using this met

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Gong, Bin, and Aimin An. "A Complex Analog Circuit Fault Diagnosis Method based on IMODA Improved Deep Belief Network." Academic Journal of Science and Technology 11, no. 2 (2024): 223–26. http://dx.doi.org/10.54097/1s651e97.

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Aiming at the problems of time-consuming and low diagnosis accuracy during the unsupervised training process of traditional DBN, an analog circuit fault diagnosis method based on Improved Multi-Objective Dragonfly Optimized Deep Belief Network (IMODA-ADBN) is proposed. The method employs an improved MODA algorithm instead of the BP algorithm, which improves the classification accuracy of the network and ameliorates the problem of being prone to falling into local optima. The algorithm is tested on three multi-objective mathematical benchmark problems and compared with three well-known meta-heu

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Nurtyawan, Rian, and Gerryn Maulannisaa. "Pemantauan Fase Pertumbuhan Tanaman Padi Menggunakan Citra Radarsat-2 Quad Polarimetrik." Jurnal Rekayasa Hijau 5, no. 1 (2021): 1–14. http://dx.doi.org/10.26760/jrh.v5i1.1-14.

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ABSTRAKIndramayu merupakan salah satu lumbung padi Indonesia yang ada di wilayah Jawa Barat dimana Badan Pusat Statistik mencatat pada tahun 2014, Indramayu menghasilkan padi sebesar 1.361.374 ton. Untuk memantau produksi padi, sangat diperlukan pemantauan fase pertumbuhan tanaman padi, salah satu metodenya dengan teknologi penginderaan jauh sistem RADAR menggunakan citra RADARSAT-2 quad polarimetrik. Penelitian ini bertujuan untuk mengklasifikasi daerah fase pertumbuhan tanaman padi menggunakan metode Cloude Pottier H/A/α (entropi/anisotropi/sudut alfa) dan mengevaluasi metode tersebut dalam

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Liu, Ying Chun, Jian Ming Zhang, De Long Zhang, et al. "30A/60V Electric Car Charger Control Circuit Simulation." Advanced Materials Research 971-973 (June 2014): 950–53. http://dx.doi.org/10.4028/www.scientific.net/amr.971-973.950.

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Through analysis and comparison of existing charging method works , adding more links constant current charging and constant voltage charging on the basis of the three-stage charging mode is proposed to receive more in line with rechargeable batteries five-phase characteristic curve charging mode. By scaling the control circuit and the PI regulator circuits use the charging current value and the constant voltage is sampled , a constant voltage corresponding to the error value to be compared and outputs the PWM control chip SG3525, causing the output current of the front end circuit chip , the

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Meng, Fangzhou, Aoping Hong, Hongying Tang, and Guanjun Tong. "FQDNet: A Fusion-Enhanced Quad-Head Network for RGB-Infrared Object Detection." Remote Sensing 17, no. 6 (2025): 1095. https://doi.org/10.3390/rs17061095.

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RGB-IR object detection provides a promising solution for complex scenarios, such as remote sensing and low-light environments, by leveraging the complementary strengths of visible and infrared modalities. Despite significant advancements, two key challenges remain: (1) effectively integrating multi-modal features within lightweight frameworks to enable real-time performance and (2) fully utilizing multi-scale features, which are crucial for detecting objects of varying sizes but are often underexploited, leading to suboptimal accuracy. To address these challenges, we propose FQDNet, a novel R

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Wang, Fengqin, Zhiying Wang, and Qiuwen Zhang. "Efficient CU Decision Algorithm for VVC 3D Video Depth Map Using GLCM and Extra Trees." Electronics 12, no. 18 (2023): 3914. http://dx.doi.org/10.3390/electronics12183914.

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The new generation of 3D video is an international frontier research hotspot. However, the large amount of data and high complexity are core problems to be solved urgently in 3D video coding. The latest generation of video coding standard versatile video coding (VVC) adopts the quad-tree with nested multi-type tree (QTMT) partition structure, and the coding efficiency is much higher than other coding standards. However, the current research work undertaken for VVC is less for 3D video. In light of this context, we propose a fast coding unit (CU) decision algorithm based on the gray level co-oc

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Golovkov, A. A., and A. V. Fomin. "Parametrical Synthesis of Radio Devices with the Set Quantity of Identical Cascades for Inclusion Variants of Jet Two-port Networks between a Nonlinear Part and Loading." Journal of the Russian Universities. Radioelectronics 24, no. 6 (2021): 27–37. http://dx.doi.org/10.32603/1993-8985-2021-24-6-27-37.

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Introduction. The ability to analytically determine some parameters of various radio devices, which are optimal according to the criterion of providing the set values of the modules and phases of transfer functions at the required number of frequencies, significantly reduces the time for numerical optimization of the rest of the parameters according to the criterion of forming the required frequency response and frequency response in the frequency band. Until now, such problems with respect to radio devices have been solved only for one stage of the "nonlinear part – matching device" or "match

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Elezaj, Elvis, and Bekë Kuqi. "Quantitative Strategic Planning Matrix as a Superior Strategic Management Tools and Techniques in Evaluating Decision Alternatives." MENDEL 29, no. 2 (2023): 90–96. http://dx.doi.org/10.13164/mendel.2023.2.090.

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Evaluation of alternatives to making decisions still remains as the most difficult field for every manager. Considering that uncertainty, stress, emotions and many other factors still remain insurmountable during decision-making in the work of managers. The research will bring a contemporary approach to the evaluation of alternatives through the multi-stage method by conducting a series of exhibitions for an effective decision. Model will create a logical structure derivation of exhibitions by revealing options and paths toward strategic leadership. The research used mixed methods of data coll

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Li, Yixiao, Lixiang Li, Yuan Fang, Haipeng Peng, and Nam Ling. "Bagged Tree and ResNet-Based Joint End-to-End Fast CTU Partition Decision Algorithm for Video Intra Coding." Electronics 11, no. 8 (2022): 1264. http://dx.doi.org/10.3390/electronics11081264.

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Video coding standards, such as high-efficiency video coding (HEVC), versatile video coding (VVC), and AOMedia video 2 (AV2), achieve an optimal encoding performance by traversing all possible combinations of coding unit (CU) partition and selecting the combination with the minimum coding cost. It is still necessary to further reduce the encoding time of HEVC, because HEVC is one of the most widely used coding standards. In HEVC, the process of searching for the best performance is the source of most of the encoding complexity. To reduce the complexity of the coding block partition in HEVC, a

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Wang, Nana. "The Analysis of Electronic Circuit Fault Diagnosis Based on Neural Network Data Fusion Algorithm." Symmetry 12, no. 3 (2020): 458. http://dx.doi.org/10.3390/sym12030458.

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Symmetries play very important roles in the dynamics of electrical systems. The relevant electronic circuits with fault diagnostics, including the optimized neural network algorithm model, are designed on the basis of symmetry principles. In order to improve the efficiency of the circuit pressure test, a circuit pressure function equivalent compression test method based on the parallel neural network algorithm is proposed. For the implementation stage of the circuit pressure test, the improved modified node algorithm (MNA) is used to build an optimization model, and the circuit network is conv

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Gao, Jiyuan, Jiang Guo, Fang Yuan, et al. "An Exploration into the Fault Diagnosis of Analog Circuits Using Enhanced Golden Eagle Optimized 1D-Convolutional Neural Network (CNN) with a Time-Frequency Domain Input and Attention Mechanism." Sensors 24, no. 2 (2024): 390. http://dx.doi.org/10.3390/s24020390.

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With the continuous operation of analog circuits, the component degradation problem gradually comes to the forefront, which may lead to problems, such as circuit performance degradation, system stability reductions, and signal quality degradation, which could be particularly evident in increasingly complex electronic systems. At the same time, due to factors, such as continuous signal transformation, the fluctuation of component parameters, and the nonlinear characteristics of components, traditional fault localization methods are still facing significant challenges when dealing with large-sca

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Zhang, Zhenxin, Meng Zhang, Guoxi Li, Shilong Qin, and Chunxiao Xu. "ATSUKF-Based Actuator Health Assessment Method for Quad-Copter Unmanned Aerial Vehicles." Drones 7, no. 1 (2022): 12. http://dx.doi.org/10.3390/drones7010012.

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The actuator, which generally consists of motors, electrical regulations, and propellers, is the key component of the quadrotor Unmanned Aerial Vehicle. During the operation of the UAV, actuators are prone to degrade performance and even cause serious failure, which affects the service quality and flight safety of Unmanned Aerial Vehicles. Therefore, timely and accurate monitoring and evaluation of the health condition of actuators is of great significance to ensure the mission reliability of UAVs. This paper proposes an Adaptive Two-stage Unscented Kalman Filter-based actuator health assessme

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Karagozov, E. Sh, E. H. Ahmadov, K. Sh Shabanov, and A. S. Shabanova. "About the application of modern geophysical research methods and the problems solved Summary." Scientific Petroleum, no. 1 (June 30, 2023): 27–31. http://dx.doi.org/10.53404/sci.petro.20230100037.

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The vast majority of oil and gas fields in Azerbaijan are at the final (late) stage of development, and therefore a natural decline in production is expected. Despite the long-term development of fields, their reserves are of great industrial importance for ensuring the stability of the energy balance of our country. Therefore, it became necessary to introduce new technologies in order to maintain or partially increase production at fields that are in long-term development. Before carrying out geological activities, it is necessary to apply a new type of more modern borehole geophysical resear

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Hill-Batorski, Lindsay, Yasuko Hatta, Michael Moser, David Marshall, and Pamuk Bilsel. "10. Quadrivalent M2SR (M2-deficient Single Replication) Live Influenza Vaccine Provides Better Protection Than Inactivated Vaccine Against Drifted Influenza B Virus Challenge in Ferrets." Open Forum Infectious Diseases 8, Supplement_1 (2021): S128—S129. http://dx.doi.org/10.1093/ofid/ofab466.212.

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Abstract Background Quadrivalent inactivated influenza vaccines (QIV) induce neutralizing antibodies (Abs) against the viral hemagglutinin (HA). Despite annual update of HA vaccine antigens to match circulating strains, current vaccines provide ~60% vaccine effectiveness (VE). QIV VE can be as low as 10% when circulating strains do not match vaccine HA. The live M2SR (M2-deficient single replication) influenza vaccine candidate has previously shown broad humoral, mucosal and cellular immune responses and protection against multiple influenza A subtypes. Here we show similar properties with the

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Zhang, Chaolong, Yigang He, Lei Zuo, Jinping Wang, and Wei He. "A Novel Approach To Diagnosis Of Analog Circuit Incipient Faults Based On KECA And OAO LSSVM." Metrology and Measurement Systems 22, no. 2 (2015): 251–62. http://dx.doi.org/10.1515/mms-2015-0025.

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Abstract Correct incipient identification of an analog circuit fault is conducive to the health of the analog circuit, yet very difficult. In this paper, a novel approach to analog circuit incipient fault identification is presented. Time responses are acquired by sampling outputs of the circuits under test, and then the responses are decomposed by the wavelet transform in order to generate energy features. Afterwards, lower-dimensional features are produced through the kernel entropy component analysis as samples for training and testing a one-against-one least squares support vector machine.

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Anurogo, Wenang, Muhammad Zainuddin Lubis, Hanah Khoirunnisa, et al. "A Simple Aerial Photogrammetric Mapping System Overview and Image Acquisition Using Unmanned Aerial Vehicles (UAVs)." Journal of Applied Geospatial Information 1, no. 01 (2017): 11–18. http://dx.doi.org/10.30871/jagi.v1i01.360.

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Aerial photogrammetry is one of the Alternative technologies for more detailed data, real time, fast and cheaper. Nowadays, many photogrammetric mapping methods have used UAV / unmanned drones or drones to retrieve and record data from an object in the earth. The application of drones in the field of geospatial science today is in great demand because of its relatively easy operation and relatively affordable cost compared to satellite systems especially high - resolution satellite imagery. This research aims to determine the stage or overview of data retrieval process with DJI Phantom 4 (mult

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Nugraha, Bondan Eka, and Zaenal Abidin. "QR-Code Based Visual Servoing and Target Recognition to Improve Payload Release Accuracy in Air Delivery Missions using Fully Autonomous Quad-Copter UAV." Recursive Journal of Informatics 3, no. 1 (2025): 59–67. https://doi.org/10.15294/rji.v3i1.4430.

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Abstract. Unmanned Aerial Vehicles (UAVs) are increasingly utilized for package delivery due to their efficiency and automation capabilities. UAVs can execute autonomous flight missions using Global Positioning System (GPS)-based navigation. However, challenges arise in the final stage of delivery, known as the last-mile delivery problem. The limitations of GPS-based navigation, the absence of recipient authentication, and shifting drop-off points create reliability and safety concerns. External factors such as varied environmental topography further contribute to delivery inaccuracies, highli

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Yuan, Hui, Yaoke Shi, Long Li, Guobi Ling, Jingxiao Zeng, and Zhiwen Wang. "Fault Diagnosis in Analog Circuits Using a Multi-Input Convolutional Neural Network with Feature Attention." Computation 13, no. 4 (2025): 94. https://doi.org/10.3390/computation13040094.

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Accurate fault diagnosis in analog circuits faces significant challenges owing to the inherent complexity of fault data patterns and the limited feature representation capabilities of conventional methodologies. Addressing the limitations of current convolutional neural networks (CNN) in handling heterogeneous fault characteristics, this study presents an efficient channel attention-enhanced multi-input CNN framework (ECA-MI-CNN) with dual-domain feature fusion, demonstrating three key innovations. First, the proposed framework addresses multi-domain feature extraction through parallel CNN bra

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Schichman, Steven A., Jennifer H. Han, Juan-Sebastian Saldivar, et al. "ATM Gene Point Mutation and Frameshift Mutation Are Found In High-Risk, Untreated Chronic Lymphocytic Leukemia Patients with Interstitial Deletion of Chromosome 11q and Uniparental Disomy of Chromosome 11q." Blood 116, no. 21 (2010): 2420. http://dx.doi.org/10.1182/blood.v116.21.2420.2420.

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Abstract Abstract 2420 Introduction: Interstitial deletion of chromosome 11q (11q-) detected by fluorescence in situ hybridization (FISH) is an unfavorable prognostic marker in chronic lymphocytic leukemia (CLL). CLL patients with 11q- often have younger age of onset, bulky lymphadenopathy, and poorer overall survival. The ataxia-telangiectasia mutated (ATM) gene, which encodes a protein kinase central to DNA damage response, is thought to be the critical gene in CLL 11q- through loss of ATM function. A subgroup of CLL patients with 11q- has been shown by other investigators to have a mutation

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Maclachlan, Kylee H., Carlyn Rose Tan, Tala Shekarkhand, et al. "Comprehensive Genomic Characterization of Response and Resistance to Daratumumab-Based Quadruplet Induction in Newly Diagnosed Multiple Myeloma Patients." Blood 142, Supplement 1 (2023): 3370. http://dx.doi.org/10.1182/blood-2023-187891.

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Introduction: Current prognostic scores for newly diagnosed multiple myeloma (NDMM) rely on measures of tumor bulk and limited genomic information. A recent artificial-intelligence-based model suggested that individualized prognostication and prediction of response to specific therapies may be improved by more comprehensive genomic assessment (IRMMa, Maura et al Blood 2022). The 20 significant genomic contributors included APOBEC mutational activity, gain/amp1q, TP53 aberration, and loss of any of CDKN2C, RPL5, FUBP1, RB1, RASA2, 10q23 or 12p13. The highest impact on progression-free (PFS) and

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Raposo, Paulo. "Geovisualization of complex origin-destination flow maps using Discrete Global Grid Systems." Abstracts of the ICA 1 (July 15, 2019): 1–3. http://dx.doi.org/10.5194/ica-abs-1-308-2019.

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<p><strong>Abstract.</strong> Flow maps, where counts of people or things are shown travelling between origin-destination pairs with paths or arrows, are difficult to draw well, mostly because they rapidly get cluttered as more and more paths are added. Researchers in cartographic and information visualization fields have sought to mitigate these problems in various ways, including cluster detection and edge bundling (Buchin, Speckmann, &amp; Verbeek, 2011; Guo, 2009), force-directed path placement (Holten &amp; van Wijk, 2009; Jenny et al., 2017), use of network topo

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Clay-Gilmour, Alyssa I., Michelle Hildebrandt, Yan Asmann, et al. "Association between a Polygenic Risk Score for Multiple Myeloma Risk and Overall Survival." Blood 134, Supplement_1 (2019): 4366. http://dx.doi.org/10.1182/blood-2019-126088.

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Background Genome-wide association studies (GWAS) conducted in populations of European ancestry (EA) have identified and confirmed 23 germline susceptibility loci for multiple myeloma (MM). The effect sizes of single nucleotide polymorphisms (SNPs) at these loci are small, therefore combining them into a single summary measure, known as a polygenic risk score (PRS), may provide a more meaningful risk factor. We have previously shown a PRS comprised of the 23 SNPs for MM contributes to increased risk of MM, with a 2.7-fold increase for highest vs. lowest PRS quintiles. Whether the MM-PRS is als

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Hartley, Christopher, Catherine E. Hagen, Sumeet K. Mittal, Joe Abdo, Sheeno P. Thyparambil, and Ajay Bansal. "STLA101 assay for the detection of cancerous progression in Barrett’s esophagus: A multi-institutional study." Journal of Clinical Oncology 40, no. 4_suppl (2022): 249. http://dx.doi.org/10.1200/jco.2022.40.4_suppl.249.

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249 Background: Since 1975, Esophageal adenocarcinoma (EAC) incidence has increased more than any other cancer (̃700%). Pre-malignant metaplastic tissue, or Barrett's Esophagus (BE), is the only known precursor for EAC. Periodic histological assessment of endoscopic biopsy along dysplasia-carcinoma sequence is used to assess progression risk. Current surveillance protocols have clinical limitations as 80% of patients still present with stage II-IV EAC. The aim of this study is to compare novel proteomic expression patterns to distinguish stable BE patients from those who developed EAC using th

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Carpenter, Chris. "Geomechanical Measurements and Machine Learning Help Predict Trouble Stages." Journal of Petroleum Technology 73, no. 04 (2021): 42–43. http://dx.doi.org/10.2118/0421-0042-jpt.

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This article, written by JPT Technology Editor Chris Carpenter, contains highlights of paper SPE 201699, “Predicting Trouble Stages With Geomechanical Measurements and Machine Learning: A Case Study of Southern Midland Basin Horizontal Completions,” by Eric Romberg, SPE, Keban Engineering; Aaron Fisher, Tracker Resources; and Joel Mazza, SPE, Fracture ID, et al., prepared for the 2020 SPE Annual Technical Conference and Exhibition, originally scheduled to be held in Denver, 5–7 October. The paper has not been peer reviewed. Unexpected problems during completion create costs that can cause a we

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Peckham-Gregory, Erin, Michael Scheurer, Rikhia Chakraborty, et al. "Inherited Genetic Risk Factors and Langerhans Cell Histiocytosis Relapse Events." Blood 132, Supplement 1 (2018): 4278. http://dx.doi.org/10.1182/blood-2018-99-118743.

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Abstract Introduction: Langerhans cell histiocytosis (LCH) is an inflammatory myeloid neoplasia characterized by lesions including pathogenic CD207+ dendritic cells among an inflammatory infiltrate, and has a median age at diagnosis of 30 months. Approximately 50% of children with LCH relapse, and 40% experience a second relapse event within two years. Sequencing studies have identified activating somatic mutations in MAPK pathway genes in ~85% of LCH lesions. Notably, LCH cases who are carriers of BRAFV600E+ experience a 2-fold increased risk of relapse. However, the role of inherited genetic

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Bonomo, Lauren, Jerry Lue, and Ajai Chari. "The Outcomes of Elderly Multiple Myeloma Patients Treated in the United States." Blood 124, no. 21 (2014): 5756. http://dx.doi.org/10.1182/blood.v124.21.5756.5756.

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Abstract Background Improvements in the prognosis for elderly multiple myeloma (MM) patients have been less pronounced than those of younger, autologous transplant-eligible patients. The latter do not typically receive low-dose, oral melphalan-based regimens, which are less potent, slower in onset of activity, and possibly more myelosuppressive than novel agents. Indeed, the FIRST phase 3 study comparing lenalidomide and dexamethasone (RD) to melphalan, prednisone, and thalidomide (MPT) has already demonstrated a significant improvement in progression free survival (PFS) with a trend towards i

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Schichman, Steven A., Annjanette Stone, Maria Winters, et al. "Complex Interstitial Deletions of 11q and Copy-Neutral Loss of Heterozygosity of 11q Are Detected by Whole Genome Copy Number Variation Analysis of Early-Intermediate Stage, High Risk Chronic Lymphocytic Leukemia Patients." Blood 114, no. 22 (2009): 1245. http://dx.doi.org/10.1182/blood.v114.22.1245.1245.

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Abstract Abstract 1245 Poster Board I-267 Introduction Chronic lymphocytic leukemia (CLL) patients with del(11q) by fluorescence in situ hybridization (FISH) have a poor prognosis. These patients often have younger age of onset, bulky lymphadenopathy, and short clinical response to treatment with purine analogues. Deletion of 11q in CLL is thought to involve loss-of-function of ataxia-telangiectasia mutated (ATM), a protein kinase central to DNA damage responses. As part of a larger study of early-intermediate stage, high risk CLL patients, we applied whole genome copy number variation (CNV) a

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Schichman, Steven A., Annjanette Stone, Maria Winters, et al. "Whole Genome Copy Number Variation Analysis of Chronic Lymphocytic Leukemia (CLL) Cells From Early-Intermediate Stage, High Risk CLL Patients Prior to First Treatment Reveals New Loss of Heterozygosity and Duplication Events in the CLL Genome." Blood 114, no. 22 (2009): 1265. http://dx.doi.org/10.1182/blood.v114.22.1265.1265.

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Abstract Abstract 1265 Poster Board I-287 Introduction Fluorescence in situ hybridization (FISH), in combination with other markers, is used as a prognostic tool for CLL patients at diagnosis. The presence or absence of trisomy 12 and deletions at 13q, 11q, and 17p helps to predict disease progression and to stratify patients for therapeutic decisions. We hypothesized that whole genome single nucleotide polymorphism (SNP)-based copy number variation (CNV) analysis would capture all of the information in current CLL FISH panels and would reveal new CNV features in the CLL genome. Patients and M

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Gandhi, Ujjawal H., Arjun Lakshman, Zhubin Gahvari, et al. "Natural History of Patients with Multiple Myeloma Refractory to CD38-Targeted Monoclonal Antibody-Based Treatment." Blood 132, Supplement 1 (2018): 3233. http://dx.doi.org/10.1182/blood-2018-99-111033.

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Abstract Introduction Proteasome inhibitors (PIs) and immunomodulatory drugs (IMiDs) have significantly improved survival in patients with multiple myeloma (MM). Refractoriness to PIs and IMiDs results in poor outcomes with a median survival of about 13 months.Daratumumab and isatuximab are CD38-targeting monoclonal antibodies (MoABs) with remarkable activity in relapsed and refractory MM. The outcome of MM patients in US clinical practice who becomes refractory to CD38 MoABs is unknown. The aim of this multicenter, retrospective study is to investigate the natural history of patients with MM

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Anderson, Blair R., Melanie E. Garrett, Karen L. Soldano, et al. "GWAS Meta-Analysis of Glomerular Filtration Rate in Three Cohorts of Sickle Cell Disease Patients and In Vivo Functional Analysis Reveals Potential Nephropathy Candidate Genes." Blood 128, no. 22 (2016): 269. http://dx.doi.org/10.1182/blood.v128.22.269.269.

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Abstract BACKGROUND: Sickle cell disease nephropathy (SCDN) is a common complication of sickle cell disease (SCD) associated with risk for early mortality (Platt et al., 1994; Elmariah et al, 2014). To identify potential genetic risk factors for SCDN, we performed genome-wide association studies (GWAS) for glomerular filtration rate (GFR) in three well-characterized SCD cohorts and performed in vivo functional analysis of one of the candidate genes in zebrafish. METHODS: Three previously described SCD cohorts were utilized in this analysis: Outcome Modifying Genes in Sickle Cell Disease (OMG-S

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Varnado, William, Megan Helena Jagosky, Zhubin Gahvari, et al. "Natural History of Patients with Multiple Myeloma Refractory to Elotuzumab and Outcomes of Subsequent Therapy with Anti-CD38 Monoclonal Antibodies." Blood 132, Supplement 1 (2018): 3303. http://dx.doi.org/10.1182/blood-2018-99-112246.

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Abstract Introduction: Monoclonal antibodies (MoAbs) have shown activity in relapsed and refractory multiple myeloma (MM). Elotuzumab is an anti-SLAMF7 MoAb that synergizes with immunomodulatory agents (IMiDs) and is approved for treatment of relapsed and refractory MM. Anti-CD38 MoAbs (daratumumab, FDA approved and isatuximab, in clinical trials) have also entered the therapeutic MM landscape but little is known about how to best sequence MoAbs and the existence of cross resistance between different classes of MoAbs. We analyzed outcomes of patients who become refractory to elotuzumab with em

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Madduri, Deepu, Ashley Rosko, Jason Brayer, et al. "REGN5458, a BCMA x CD3 Bispecific Monoclonal Antibody, Induces Deep and Durable Responses in Patients with Relapsed/Refractory Multiple Myeloma (RRMM)." Blood 136, Supplement 1 (2020): 41–42. http://dx.doi.org/10.1182/blood-2020-139192.

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Background Multiple myeloma (MM) is characterized by expression of the cell surface protein B-cell maturation antigen (BCMA), a validated target for therapeutic intervention. REGN5458 is a BCMA x CD3 bispecific antibody (Ab) that binds to both BCMA and CD3, thereby targeting MM cells with T-cell effector function via BCMA. Previously, we presented data showing REGN5458 has an acceptable safety profile with evidence of clinical efficacy in heavily pre-treated patients with RRMM. Here we describe the updated safety and response durability in a Phase 1 trial of REGN5458 monotherapy in patients wi

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Fu, Yuhua. "Creating Generalized and Hybrid Set and Library with Neutrosophy and Quad-stage Method." December 5, 2014. https://doi.org/10.5281/zenodo.22972.

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Generalized and hybrid set can be created with neutrosophy and quad-stage method. Firstly the generalized and hybrid neutrosophic set is discussed. Based on this, the concepts of "problem set", "solution set", "principle set", "law set", "theory set", "formula set", and the like are presented; Secondly the combination or synthetical body of generalized and hybrid sets is named as "library" (various generalized and hybrid sets can be put into the related "library"); such as "mathematics library", "phy

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Fu, Yuhua. "Expanding Newton Mechanics with Neutrosophy and Quadstage Method - New Newton Mechanics Taking Law of Conservation of Energy as Unique Source Law." Neutrosophic Sets and Systems 3, 2014 (May 4, 2014). https://doi.org/10.5281/zenodo.571374.

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Neutrosophy is a new branch of philosophy, and "Quad-stage" (Four stages) is the expansion of Hegel’s triad thesis, antithesis, synthesis of development. Applying Neutrosophy and "Quad-stage" method, the purposes of this paper are expanding Newton Mechanics and making it become New Newton Mechanics (NNW) taking law of conservation of energy as unique source law. In this paper the examples show that in some cases other laws may be contradicted with the law of conservation of energy.

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Fu, Yuhua. "Negating Four Color Theorem with Neutrosophy and Quadstage Method." Neutrosophic Sets and Systems 8, 2015 (May 4, 2015). https://doi.org/10.5281/zenodo.571486.

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With the help of Neutrosophy and Quad-stage Method, the proof for negation of “the four color theorem” is given. In which the key issue is to consider the color of the boundary, thus “the two color theorem” and “the five color theorem” are derived to replace "the four color theorem".

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Fu, Yuhua. "Negating Four Color Theorem with Neutrosophy and Quadstage Method." July 1, 2015. https://doi.org/10.5281/zenodo.22571.

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With the help of Neutrosophy and Quad-stage Method, the proof for negation of “the four color theorem” is given. In which the key issue is to consider the color of the boundary, thus “the two color theorem” and “the five color theorem” are derived to replace "the four color theorem".

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Fu, Yuhua. "Expanding Uncertainty Principle to Certainty-Uncertainty Principles with Neutrosophy and Quad-stage Method." August 3, 2015. https://doi.org/10.5281/zenodo.22465.

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The most famous contribution of Heisenberg is uncertainty principle. But the original uncertainty principle is improper. Considering all the possible situations (including the case that people can create laws) and applying Neutrosophy and Quad-stage Method, this paper presents "certainty-uncertainty principles" with general form and variable dimension fractal form. According to the classification of Neutrosophy, "certainty-uncertainty principles" can be divided into three principles in different conditions: "certainty principle&q

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Yuhua, Fu. "Point Equation, Line Equation, Plane Equation etc and Point Solution, Line Solution, Plane Solution etc —Expanding Concepts of Equation and Solution with Neutrosophy and Quad-stage Method." May 4, 2016. https://doi.org/10.5281/zenodo.50929.

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The concepts of equations and solutions are constantly developed and expanded. With Neutrosophy and Quad-stage method, this paper attempts to expand the concepts of equations and solutions in the way of referring to the concepts of domain of function, the geometry elements included in domain of function, and the like; and discusses point equation, line equation, plane equation, solid equation, sub-domain equation, whole-domain equation, and the like.

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Fu, Yuhua. "Expanding Newton Mechanics with Neutrosophy and Quadstage Method ──New Newton Mechanics Taking Law of Conservation of Energy as Unique Source Law." July 1, 2015. https://doi.org/10.5281/zenodo.22464.

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Neutrosophy is a new branch of philosophy, and "Quad-stage" (Four stages) is the expansion of Hegel’s triad thesis, antithesis, synthesis of development. Applying Neutrosophy and "Quad-stage" method, the purposes of this paper are expanding Newton Mechanics and making it become New Newton Mechanics (NNW) taking law of conservation of energy as unique source law. In this paper the examples show that in some cases other laws may be contradicted with the law of conservation of energy. The original Newton's three laws and the la

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Hoffmann, Alex Paul, Mark B. Moldwin, Brady P. Strabel, and Lauro V. Ojeda. "Enabling Boomless CubeSat Magnetic Field Measurements with the Quad‐Mag Magnetometer and an Improved Underdetermined Blind Source Separation Algorithm." Journal of Geophysical Research: Space Physics, August 25, 2023. http://dx.doi.org/10.1029/2023ja031662.

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AbstractIn situ magnetic field measurements are often difficult to obtain due to the presence of stray magnetic fields generated by spacecraft electrical subsystems. The conventional solution is to implement strict magnetic cleanliness requirements and place magnetometers on a deployable boom. However, this method is not always feasible on low‐cost platforms due to factors such as increased design complexity, increased cost, and volume limitations. To overcome these problems, we propose using the Quad‐Mag CubeSat magnetometer with an improved Underdetermined Blind Source Separation (UBSS) nois

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Agresti, Roberto, Marco Sandri, Giuseppe Capri, et al. "Axillary surgery versus no-axillary staging in T1N0 breast cancer: 20-year follow-up of the INT 09/98 randomized clinical trial." British Journal of Surgery 112, no. 3 (2025). https://doi.org/10.1093/bjs/znae311.

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Abstract Background The role of axillary surgery in breast cancer has shifted over time from a therapeutic operation to a staging method for subsequent adjuvant therapies, through the introduction of sentinel lymph node biopsy. The discovery of molecular subtypes has since questioned the necessity of axillary staging in breast cancer. Methods The INT09/98 randomized trial explored the omission of axillary surgery in early-stage breast cancer in patients under 65 years of age. From June 1998 to June 2003, a total of 565 T1N0 breast cancer patients were enrolled. The trial tested the non-inferio

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Yu, Youmin, Victor Chiriac, Yingwei Jiang, and Zhijie Wang. "Sequential Reflow-Process Optimization to Reduce Die-Attach Solder Voids." Journal of Electronic Packaging 137, no. 2 (2015). http://dx.doi.org/10.1115/1.4029569.

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Solder voids are detrimental to the thermal, mechanical, and reliability performance of integrated circuit (IC) packages and must be controlled within certain specifications. A sequential method of optimizing solder-reflow process to reduce die-attach solder voids in power quad flat no-lead (QFN) packages is presented. The sequential optimization consists, in turn, of theoretical prediction, heat transfer comparison, and experimental validation. First, the theoretical prediction uses calculations to find the optimal pause location and time for a lead frame strip (with dies bonded to it by sold

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Fu, Yuhua. "Point Equation, Line Equation, Plane Equation etc and Point Solution, Line Solution, Plane Solution etc. - Expanding Concepts of Equation and Solution with Neutrosophy and Quad-stage Method." Neutrosophic Sets and Systems 11, 2016 (May 5, 2016). https://doi.org/10.5281/zenodo.571573.

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The concepts of equations and solutions are constantly developed and expanded. With Neutrosophy and Quad-stage method, this paper attempts to expand the concepts of equations and solutions in the way of referring to the concepts of domain of function, the geometry elements included in domain of function, and the like; and discusses point equation, line equation, plane equation, solid equation, sub-domain equation, whole-domain equation, and the like; as well as point solution, line solution, plane solution, solid solution, sub-domain solution, whole-domain solution, and the like. Where: the po

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Nguyen, Sang Quang, Tien Huu Vu, Duong Trieu Dinh, Minh Bao Dinh, Minh Ngoc Do, and Xiem Hoang. "Early CTU Termination and Three-steps Mode Decision Method for Fast Versatile Video Coding." VNU Journal of Science: Computer Science and Communication Engineering, December 16, 2022. http://dx.doi.org/10.25073/2588-1086/vnucsce.375.

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Versatile Video Coding (VVC) has been recently becoming popular in coding videos due to its compression efficiency. To reach this performance, Joint Video Experts Team (JVET) has introduced a number of improvement techniques to VVC coding model. Among them, VVC Intra coding introduces a new concept of quad-tree nested multi-type tree (QTMT) and extends the predicted modes with up to 67 options. As a result, the complexity of the VVC Intra encoding also greatly increases. To make VVC Intra coding more feasible in real-time applications, we propose in this paper a novel deep learning based fast

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Takaba, Kiyofumi, Saori Maki-Yonekura, Satoru Inoue, Tatsuo Hasegawa, and Koji Yonekura. "Protein and Organic-Molecular Crystallography With 300kV Electrons on a Direct Electron Detector." Frontiers in Molecular Biosciences 7 (January 6, 2021). http://dx.doi.org/10.3389/fmolb.2020.612226.

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Electron 3D crystallography can reveal the atomic structure from undersized crystals of various samples owing to the strong scattering power of electrons. Here, a direct electron detector DE64 was tested for small and thin crystals of protein and an organic molecule using a JEOL CRYO ARM 300 electron microscope. The microscope is equipped with a cold-field emission gun operated at an accelerating voltage of 300 kV, quad condenser lenses for parallel illumination, an in-column energy filter, and a stable rotational goniometer stage. Rotational diffraction data were collected in an unsupervised

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Raghad, Jawad Ahmed. "Genetic-Based Multi Resolution Noisy Color Image Segmentation." September 20, 2010. https://doi.org/10.5281/zenodo.1076486.

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Segmentation of a color image composed of different kinds of regions can be a hard problem, namely to compute for an exact texture fields. The decision of the optimum number of segmentation areas in an image when it contains similar and/or un stationary texture fields. A novel neighborhood-based segmentation approach is proposed. A genetic algorithm is used in the proposed segment-pass optimization process. In this pass, an energy function, which is defined based on Markov Random Fields, is minimized. In this paper we use an adaptive threshold estimation method for image thresholding in the wa

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Vali, S. Haji, B. Viswanath, T. Gousiya, M. Lalitha, N. Gangavamsi, and M. Maneesha. "Video Compression Using Matlab." International Journal For Multidisciplinary Research 7, no. 2 (2025). https://doi.org/10.36948/ijfmr.2025.v07i02.42132.

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Video compression is the main topic of this research. HD quality videos with smaller sizes are required for video calls, conferences, and transmission. We can get better video compression by implementing the suggested strategy. A successful low-memory solution must be offered in order to implement the SPIHT algorithm. The sorting and refining stages are merged into a single scan run in this updated technique. In order to alter the original SPIHT algorithm, we introduce two new ideas: the number of mistake bits and the absolute zero tree. This study looks at the coding method for compressing me

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