Relevant bibliographies by topics / Quinazoline compounds

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Quinazoline compounds'

Author: Grafiati
Published: 5 June 2025
Last updated: 1 August 2025

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Journal articles on the topic "Quinazoline compounds"

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Abu-Hashem, Ameen. "Synthesis of New Furothiazolo Pyrimido Quinazolinones from Visnagenone or Khellinone and Antimicrobial Activity." Molecules 23, no. 11 (2018): 2793. http://dx.doi.org/10.3390/molecules23112793.

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Substituted-6-methyl-1-thioxo-1,2-dihydro-3H-furo[3,2-g]pyrimido[1,6-a]quinazolin-3-ones (5a,b) were synthesized from condensation of visnagenone (2a) or khellinone (2b) with 6-amino-thiouracil (3) in dimethylformamide or refluxing of (4a) or (4b) in dimethylformamide. Hence, compounds (5a,b) were used as the starting materials for preparing many new heterocyclic compounds such as; furo[3,2-g]pyrimido[1,6-a]quinazoline (6a,b), furo[3,2-g]thiazolo[2′,3′:2,3]pyrimido[1,6-a]quinazolinone (7a,b), substituted-benzylidene-furo[3,2-g]thiazolo[2′,3′:2,3]pyrimido[1,6-a]quinazoline-3,5-dione (8a–f), 3-o
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Vishwakarma, Lav Kush Kumar, and Varsha Kashaw. "Nanocatalyzed Synthetic Approach for the Quinazolinone and Quinazoline Derivatives: A Review (2015 – Present)." Journal of Drug Delivery and Therapeutics 13, no. 3 (2023): 171–83. http://dx.doi.org/10.22270/jddt.v13i3.5765.

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Due to their diverse chemical reactivities and essential range of biological action, quinazolines and their derivatives rank among the most significant heterocyclic compounds. Quinazoline and quinazolinone scaffolds pharmacological properties have sparked medicinal chemists' interest in creating original medications or drug candidates. The growth of quinazoline hybrid lead compounds and the related heterocycles is summarised in the current review of medicinal chemistry. Additionally, by shedding light on the potential significance of these hybridised pharmacophoric characteristics in the demon
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Asif, Mohammad. "Chemical Characteristics, Synthetic Methods, and Biological Potential of Quinazoline and Quinazolinone Derivatives." International Journal of Medicinal Chemistry 2014 (November 13, 2014): 1–27. http://dx.doi.org/10.1155/2014/395637.

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The heterocyclic fused rings quinazoline and quinazolinone have drawn a huge consideration owing to their expanded applications in the field of pharmaceutical chemistry. Quinazoline and quinazolinone are reported for their diversified biological activities and compounds with different substitutions bring together to knowledge of a target with understanding of the molecule types that might interact with the target receptors. Quinazolines and quinazolinones are considered as an important chemical for the synthesis of various physiological significance and pharmacological utilized molecules. Quin
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Peter Osarodion Osarumwense, Mary Olire Edema, and Cyril Odianosen Usifoh. "Synthesis and antibacterial activities of quinazolin-4(3h)-one, 2-methyl-4(3h)-quinazolinone and 2–phenyl-4(3h)-quinazolinone." International Journal of Biological and Pharmaceutical Sciences Archive 1, no. 2 (2021): 077–84. http://dx.doi.org/10.30574/ijbpsa.2021.1.2.0027.

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Background: Quinazoline and quinazolinone scaffolds represent an important class of biologically active nitrogen heterocyclic compounds. Many marketed drugs are based on these moieties. A diverse range of molecules with quinazoline/quinazolinone moieties have been reported to exhibit broad spectrum of biological activities Objective: This study is aimed at the synthesis of these quinazolinone derivatives, quinazolin-4(3H)-One, 2-Methyl-4(3H)-quinazolinone and 2–Phenyl-4(3H)-quinazolin-4(3H)–one and evaluate them for their antibacterial activities. Method: The consolidation of 2-amino-methyl-4-
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Starikova, Alla Andreevna, Alexandra Aleksandrovna Tsibizova, and Marina Aleksandrovna Samotrueva. "BIOLOGICAL ACTIVITY OF NATURAL QUINAZOLINE ALKALOIDS." Chemistry of plant raw material, no. 2 (May 4, 2025): 47–73. https://doi.org/10.14258/jcprm.20250214908.

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To date, quinazoline alkaloids of natural origin, as well as synthetic derivatives based on them, whose structure contains an aromatic heterocyclic system including a pyrimidine cycle and a benzoin ring connected to it, are promising according to the criterion of the optimal profile of pharmacological activity. Currently, several hundred compounds of the quinazoline nature have been identified with a wide range of biological activities, including psychotropic (antidepressant, antipsychotic, sedative, hypnotic, anticonvulsant, etc.), antiplatelet, hypotensive, anti-inflammatory, antioxidant and
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Alla, Manjula, Gal Potuganti, and Divakar Indukuri. "An Efficient One-Pot Multicomponent Synthesis of Tetracyclic Quinazolino[4,3-b]quinazolines by Sequential C–N Bond Formation and Copper-Mediated Aerobic Oxidative Cyclization." Synlett 29, no. 13 (2018): 1717–22. http://dx.doi.org/10.1055/s-0036-1591578.

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An efficient one-pot synthesis of quinazolino[4,3-b]quinazoline derivatives has been accomplished, starting from 2-(2-bromo­phenyl)quinazolin-4(3H)-one, aldehydes, and various nitrogen sources under aerobic conditions. The multicomponent protocol is mediated by copper(I) salts and involves amination of 2-(2-bromophenyl)quinazolin-4(3H)-one, followed by condensation with the aldehyde and an oxidative cyclization to give the target compounds in moderate to good yields.
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Widiyana, Anita Puspa. "COMPUTATION DESIGN OF QUINAZOLINE-4(3H)-ON DERIVATIVES AS CYCLOOXYGENASE-2 (COX-2) INHIBITOR." Jurnal Farmasi Sains dan Praktis 7, no. 2 (2021): 163–70. http://dx.doi.org/10.31603/pharmacy.v7i2.4827.

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 The 3-(benzylideneamino)-2-(2,4-dichlorophenyl)-quinazoline-4(3H)-ones (BDCQ) are compounds developed as anticancer drugs and quinazolines. The activity and bioavailability of BDCQ derivatives as anticancer compounds that inhibit COX-2 can be predicted by computer programs and online servers. Substituents are added at positions 2 and 3 to the quinazoline-4(3H)-on ring, such as -H, -NO2, -OCH3, -N(CH3)2, -SO2NH2, -OH, and –OCH3. QSAR as COX-2 inhibitor analysis was performed by SPSS Ver. 21 software. Lipinski’s rule of five for determining bioavailability is performe
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Martynenko, Yulya, Oleksii Antypenko, Inna Nosulenko, Galina Berest, and Sergii Kovalenko. "Directed Search of Anti-inflammatory Agents Among (3HQuinazoline- 4-ylidene)hydrazides of N-protected Amino acids and their Heterocyclization Products." Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry 19, no. 1 (2020): 61–73. http://dx.doi.org/10.2174/1871523018666190115092215.

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Background: (Quinazoline-4-ylidene)hydrazides are valued intermediates in modern organic chemistry, as they are commonly used for the synthesis of substituted [1,2,4]triazolo[1,5-c]quinazolines. Objective: Unknown N-acyl-2-([1,2,4]triazolo[1,5-c]quinazoline-2-yl)-alkyl-(alkaryl-, aryl-) amines were synthesized and evaluated for anti-inflammatory potential. Methods: The peculiarities of the synthesized compounds structures were studied by IR-, NMR spectroscopy and chromatography-mass spectrometry and were discussed in detail. Probable molecular mechanisms of activity (inhibition of COX-1 and CO
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Aly, A. A. "Synthesis And Antimicrobial Activity Of Some Annelated Quinazoline Derivatives." Zeitschrift für Naturforschung B 61, no. 8 (2006): 1012–20. http://dx.doi.org/10.1515/znb-2006-0814.

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A highly efficient and versatile synthetic approach to the synthesis of annelated quinazoline derivatives viz. 3,4,9,10a-tetraazaphenanthrenes 5 - 7, thiazolidinylquinazoline 9, 2,4,9,10a-tetraazaphenanthrene 11, quinazolino[4,3-b]quinazolin-8-one 12 and imidazoquinazolines 14a,b, 15. Also, a variety of pyrazolylquinazolines 19 - 21, pyrimidinylquinazolines 22a,b were obtained via a sequence of heterocyclization reactions of 4-methyl-N-[4-(4-oxo-3,4-dihydroquinazolin-2-yl)phenyl]benzenesulfonamide (2) with different reagents. The new compounds were synthesized with the objective of study their
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Alkhathlan, H. Z., M. A. Al-Saad, H. M. Al-Hazimi, K. A. Al-Farhan, and A. A. Mousa. "Quinazoline, Pyrazolo[1,5-c]Quinazoline and Spiro Quinazoline Dimers from the Reaction of 2-Aminoacetophenone Hydrazones with Triphosgene." Journal of Chemical Research 2002, no. 12 (2002): 587–88. http://dx.doi.org/10.3184/030823402103170952.

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The reaction of hydrazones of 2-aminoacetophenone with triphosgene in dichloromethane or benzene in the presence of triethylamine gave quinazolines, pyrazolo[1,5-c]quinazoline and spiro quinazoline dimers. The latter compounds are being reported for the first time. In addition, a 4,4-disubstituted quinazoline derivative is prepared and its x-ray crystal structure is reported.
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Dissertations / Theses on the topic "Quinazoline compounds"

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Esvan, Yannick. "Conception et synthèse de nouveaux composés hétéroaromatiques inhibiteurs potentiels de kinases." Thesis, Clermont-Ferrand 2, 2016. http://www.theses.fr/2016CLF22743.

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Depuis la mise en évidence de l’existence des protéines kinases vers la fin des années 1950 cette famille d’enzymes s’est vu attribuer d’importants rôles dans divers mécanismes pathologiques notamment dans des processus de cancérisations. Plus récemment ces enzymes ont été identifiées comme potentiellement impliquées dans d’autres types de maladies telles que les maladies neurodégénératives.Deux projets de recherche seront présentés. Le premier projet expose la conception et la synthèse de nouveaux composés tricycliques de la famille des pyrido[3,4-g]quinazolines. Les propriétés inhibitrices d
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Cardoso, Leandro 1979. "Utilização farmacológica de um composto inédito derivado de quinazolina como inibidor potencial da quinase de adesão focal (FAK) no processo de hipertrofia cardíaca em camundongo = Pharmacological use of a novel compound quinazoline derivative as potential inhibitor of the focal adhesion kinase in the process of cardiac hypertrophy in mice." [s.n.], 2012. http://repositorio.unicamp.br/jspui/handle/REPOSIP/310205.

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Orientador: Kleber Gomes Franchini<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-08-20T23:08:02Z (GMT). No. of bitstreams: 1 Cardoso_Leandro_M.pdf: 3831901 bytes, checksum: 40e5df211d7e6fd923f654bd8d3a1ec1 (MD5) Previous issue date: 2012<br>Resumo: Nas doenças do coração ocorre hipertrofia e remodelamento do ventrículo esquerdo com impacto negativo na evolução clínica. Esses fatores influenciam independentemente o risco cardiovascular por elevarem a predisposição a infartos do miocárdio, ao desenvolvimento de
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Paumo, Hugues Kamdem. "2-Aryl-6,8-Dibromo-4-Chloroquinazoline as scaffold for the synthesis of Novel 2,6,8-Triaryl-4-(Phenylethynyl)Quinazolines with potential photophysical properties." Diss., 2014. http://hdl.handle.net/10500/14197.

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The 2-aryl-6,8-dibromoquinazolin-4(3H)-ones were prepared in a single-pot operation by condensing 6,8-dibromoanthranilamide and aryl aldehydes in the presence of molecular iodine in ethanol. Treatment of the 2-aryl-6,8-dibromoquinazolin-4(3H)-ones with thionylchloride in the presence of dimethylformamide afforded the corresponding 2-aryl-4-chloro-6,8-dibromoquinazolines. Palladium(0)-copper iodide catalysed Sonogashira cross-coupling reaction of 2-aryl-4-chloro-6,8-dibromoquinazolines with terminal alkynes at room temperature afforded series of 2-aryl-6,8-dibromo-4-(alkynyl)quinazolines. Furth
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Books on the topic "Quinazoline compounds"

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Brown, D. J. Quinazolines. Wiley, 1996.

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Quinoxalines. Wiley, 2004.

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Brown, Desmond J. Quinazolines, Supplement 1. Wiley & Sons, Incorporated, John, 2007.

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Brown, Desmond J. Quinazolines, Supplement 1. Wiley & Sons, Incorporated, John, 2009.

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Joshi, B. L. Some studies with quinazolines and related compounds. 1985.

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Book chapters on the topic "Quinazoline compounds"

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of nickel(II) complex with quinazoline ligand." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 5. Springer Berlin Heidelberg, 2022. http://dx.doi.org/10.1007/978-3-662-65098-1_321.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of manganese(II) complex with quinazoline ligand." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 5. Springer Berlin Heidelberg, 2022. http://dx.doi.org/10.1007/978-3-662-65098-1_56.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of cobalt(II) complex with quinazoline ligand." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 5. Springer Berlin Heidelberg, 2022. http://dx.doi.org/10.1007/978-3-662-65098-1_245.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of copper(II) complex with quinazoline ligand." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 5. Springer Berlin Heidelberg, 2022. http://dx.doi.org/10.1007/978-3-662-65098-1_411.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of copper(II) chloride complex with 2-methyl-3-amino(3H)-quinazolin-4-one." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-53974-3_457.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of copper(II) bromide complex with 2-methyl-3-amino(3H)-quinazolin-4-one." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-53974-3_458.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of copper(II) perchlorate complex with 2-methyl-3-amino(3H)-quinazolin-4-one." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-53974-3_459.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of copper(II) nitrate complex with 2-methyl-3-amino(3H)-quinazolin-4-one." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-53974-3_460.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of copper(II) sulphate complex with 2-methyl-3-amino(3H)-quinazolin-4-one." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-53974-3_461.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of copper(II) thiocyanate complex with 2-methyl-3-amino(3H)-quinazolin-4-one." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-53974-3_462.

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Conference papers on the topic "Quinazoline compounds"

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Fadil MOUSA, Enaam, and Ibtissam Khalifa JASSIM. "SYNTHESIS ,CHARACTERIZATION AND BIOLOGICAL ACTIVITY STUDY OF SOME HETEROCYCLIC COMPOUNDS." In IV.International Scientific Congress of Pure,Appliedand Technological Sciences. Rimar Academy, 2022. http://dx.doi.org/10.47832/minarcongress4-18.

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Heterocycles are an important class of organic compounds because of their applications in medicines and industrial fields. Therefore our study included preparation of these compound such as oxazepine and quinazoline rings, which were prepared through two steps: The first step included the reaction of the Schiff bases derived from sulfamethaxazole (1-4) with each of phthalic anhydride and 3- nitrophthalic anhydride for the preparation of oxazepines (5-12) .While the second step included the preparation of quinazoline compounds (13-16) from the reaction of Schiff bases (1-4) with anthranilic aci
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Tojiboev, Akmaljon, Sherzod Zhurakulov, Ulli Englert, et al. "Hirshfeld surface analysis and energy framework for crystals of quinazoline methylidene bridged compounds." In The 2nd International Online Conference on Crystals. MDPI, 2020. http://dx.doi.org/10.3390/iocc_2020-07235.

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Mohan, Chandra, Jenifer Robinson, and Arvind Negi. "Ion-Selective Electrode (ISE) Based on Polyvinyl Chloride Membrane Formed from Heterocyclic Quinazoline Compounds as Ionophore material." In CSAC 2023. MDPI, 2023. http://dx.doi.org/10.3390/csac2023-14914.

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Turgunov, Kambarali, and Ulli Englert. "Metal halide coordination compounds with 4(3H)-quinazolinone." In The 2nd International Online Conference on Crystals. MDPI, 2020. http://dx.doi.org/10.3390/iocc_2020-07334.

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Antypenko, Lyudmyla Mykolaivna, and Oleksii Mykolaiovych Antypenko. "Machine learning-driven identification of multi-targeted lead compounds among 5,6-dihydrotetrazolo[1,5-c]quinazolines for neurodegenerative and neglected tropical diseases." In СУЧАСНІ НАПРЯМИ ЗМІН В УПРАВЛІННІ ОХОРОНОЮ ЗДОРОВ’Я: МОДЕРНІЗАЦІЯ, ЯКІСТЬ, КОМУНІКАЦІЯ. Liha-Pres, 2024. http://dx.doi.org/10.36059/978-966-397-406-4-41.

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