Relevant bibliographies by topics / Quinazolinone synthesis

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Quinazolinone synthesis'

Author: Grafiati
Published: 4 June 2021
Last updated: 1 February 2022

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Journal articles on the topic "Quinazolinone synthesis"

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Asif, Mohammad. "Chemical Characteristics, Synthetic Methods, and Biological Potential of Quinazoline and Quinazolinone Derivatives." International Journal of Medicinal Chemistry 2014 (November 13, 2014): 1–27. http://dx.doi.org/10.1155/2014/395637.

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The heterocyclic fused rings quinazoline and quinazolinone have drawn a huge consideration owing to their expanded applications in the field of pharmaceutical chemistry. Quinazoline and quinazolinone are reported for their diversified biological activities and compounds with different substitutions bring together to knowledge of a target with understanding of the molecule types that might interact with the target receptors. Quinazolines and quinazolinones are considered as an important chemical for the synthesis of various physiological significance and pharmacological utilized molecules. Quinazolines and quinazolinone are a large class of biologically active compounds that exhibited broad spectrum of biological activities such as anti-HIV, anticancer, antifungal, antibacterial, antimutagenic, anticoccidial, anticonvulsant, anti-inflammatory, antidepressant, antimalarial, antioxidant, antileukemic, and antileishmanial activities and other activities. Being considered as advantaged scaffold, the alteration is made with different substituent.
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Abu-Hashem, Ameen. "Synthesis of New Furothiazolo Pyrimido Quinazolinones from Visnagenone or Khellinone and Antimicrobial Activity." Molecules 23, no. 11 (October 27, 2018): 2793. http://dx.doi.org/10.3390/molecules23112793.

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Substituted-6-methyl-1-thioxo-1,2-dihydro-3H-furo[3,2-g]pyrimido[1,6-a]quinazolin-3-ones (5a,b) were synthesized from condensation of visnagenone (2a) or khellinone (2b) with 6-amino-thiouracil (3) in dimethylformamide or refluxing of (4a) or (4b) in dimethylformamide. Hence, compounds (5a,b) were used as the starting materials for preparing many new heterocyclic compounds such as; furo[3,2-g]pyrimido[1,6-a]quinazoline (6a,b), furo[3,2-g]thiazolo[2′,3′:2,3]pyrimido[1,6-a]quinazolinone (7a,b), substituted-benzylidene-furo[3,2-g]thiazolo[2′,3′:2,3]pyrimido[1,6-a]quinazoline-3,5-dione (8a–f), 3-oxo-furo[3,2-g]pyrimido[1,6-a]quinazoline-pentane-2,4-dione (9a,b), 1-(pyrazole)-furo[3,2-g]pyrimido[1,6-a]quinazolinone (10a,b), 2-(oxo or thioxo)-pyrimidine-furo[3,2-g]pyrimido[1,6-a]quinazolinone (11a–d), 1-(methylthio)-furo[3,2-g]pyrimido[1,6-a]quinazolinone (12a,b), 1-(methyl-sulfonyl)-furo[3,2-g]pyrimido[1,6-a]quinazolinone (13a,b) and 6-methyl-1-((piperazine) or morpholino)-3H-furo[3,2-g]pyrimido[1,6-a]quinazolin-3-one (14a–d). The structures of the prepared compounds were elucidated on the basis of spectral data (IR, 1H-NMR, 13C-NMR, MS) and elemental analysis. Antimicrobial activity was evaluated for the synthesized compounds against Gram-positive, Gram-negative bacteria and fungi. The new compounds, furothiazolo pyrimido quinazolines 8a–f and 11a–d displayed results excellent for growth inhibition of bacteria and fungi.
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Komar, Mario, Maja Molnar, and Anastazija Konjarević. "Screening of Natural Deep Eutectic Solvents for Green Synthesis of 2-methyl-3-substituted Quinazolinones and Microwave-Assisted Synthesis of 3-aryl Quinazolinones in Ethanol." Croatica chemica acta 92, no. 4 (2020): 511–17. http://dx.doi.org/10.5562/cca3597.

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In this study, two fast and efficient protocols for green synthesis of 3-substituted quinazolinones were perfomed. A synthesis of 2-methyl-3-substituted quinazolinones was performed in natural deep eutectic solvents, while 3-aryl quinazolinones were obtained by using microwave assisted synthesis. Benzoxazinone, which was used as an intermediate in the synthesis of 2-methyl-3-substituted quinazolinones, was prepared conventionally from anthranilic acid and acetic anhydride. In order to find the most appropriate synthetic path, twenty natural deep eutectic solvents were applied as a solvent in these syntheses. Choline chloride:urea (1 : 2) was found to be the most efficient solvent and was further used in the synthesis of 2-methyl quinazolinone derivatives (2–12). 3-Aryl quinazolinones (13–17), on the other hand, were synthesized in one-pot microwave-assisted reaction of anthranilic acid, different amines and trimethyl orthoformate. All compounds were synthesized in good to excellent yields, characterized by LC-MS/MS spectrometry and 1H- and 13C-NMR spectroscopy.
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Mishra, AD. "A New Route for the Synthesis of Quinazolinones." Nepal Journal of Science and Technology 12 (July 22, 2012): 133–38. http://dx.doi.org/10.3126/njst.v12i0.6491.

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Quinazolinone derivatives are highly bioactive heterocyclic compounds with wider range of microbial activities such as anti-malarial, anti-cancer, anti-inflammatory, anti-hypertensive, anti-convulsant, anti-HIV, etc. Solid supported microwave synthesis of some 3-substituted-4-(2H)-quinazolinones has been carried out by the reaction of anthranilic acid, formaldehyde and primary aromatic amines. The usage of hazardous reagents and organic solvents has been avoided. The reactions were conducted in presence of acidic alumina where formaldehyde entered into cycloaddition to yield the quinazolinone derivatives. The reactions completed within 2-4 minutes with 82-94% of yields in microwave reactions while it took 5-7 hours for completion affording only 56-68% of the yields in conventional reactions. The synthesized quinazolinone derivatives showed moderate to promising antibacterial and antifungal activities.DOI: http://dx.doi.org/10.3126/njst.v12i0.6491 Nepal Journal of Science and Technology 12 (2011) 133-138
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Mahmoud, Mahmoud Refaee, Manal Mohamed El-Shahawi, and Fatma Saber Mohamed Abu El-Azm. "Synthesis of novel quinazolinone and fused quinazolinones." European Journal of Chemistry 2, no. 3 (September 30, 2011): 404–9. http://dx.doi.org/10.5155/eurjchem.2.3.404-409.267.

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Abdel-Megeed, Mohamed Farghali, and Abderrahman Teniou. "Synthesis of some 3-substituted 4(3H)-quinazolinone and 4(3H)-quinazolinethione derivatives and related fused biheterocyclic ring systems." Collection of Czechoslovak Chemical Communications 53, no. 2 (1988): 329–35. http://dx.doi.org/10.1135/cccc19880329.

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The reactions of 2-phenyl-4(3H)-quinazoline, 2-phenyl-3-amino-4(3H)-quinazolinone, and corresponding thiones with phenyl isocyanate or phenyl isothiocyanate were investigated. The resulting urea and thiourea quinazolinone or quinazolinethione derivatives reacted with hydrazine hydrate, phenylhydrazine, and urea or thiourea to form fused biheterocyclic ring systems with potential biological activities. The products were identified by IR, 1H NMR, and mass spectroscopy.
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Peter Osarodion Osarumwense, Mary Olire Edema, and Cyril Odianosen Usifoh. "Synthesis and antibacterial activities of quinazolin-4(3h)-one, 2-methyl-4(3h)-quinazolinone and 2–phenyl-4(3h)-quinazolinone." International Journal of Biological and Pharmaceutical Sciences Archive 1, no. 2 (April 30, 2021): 077–84. http://dx.doi.org/10.30574/ijbpsa.2021.1.2.0027.

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Background: Quinazoline and quinazolinone scaffolds represent an important class of biologically active nitrogen heterocyclic compounds. Many marketed drugs are based on these moieties. A diverse range of molecules with quinazoline/quinazolinone moieties have been reported to exhibit broad spectrum of biological activities Objective: This study is aimed at the synthesis of these quinazolinone derivatives, quinazolin-4(3H)-One, 2-Methyl-4(3H)-quinazolinone and 2–Phenyl-4(3H)-quinazolin-4(3H)–one and evaluate them for their antibacterial activities. Method: The consolidation of 2-amino-methyl-4-methoxybenzoate with acetic anhydride produced the cyclic compound 2-methyl-4, 5-disubstituted-1, 3-benzo-oxazine-4-one which also produce a novel 2,3-disubstituted quinazolin-4 ones via the reaction with hydrazine hydrate. The quinazolinone derivatives quinazolin-4(3H)-One, 2-Methyl-4(3H)-quinazolinone and 2–Phenyl-4(3H)-quinazolin-4(3H)–one were evaluated pharmacologically for their in vivo analgesic activities by acetic acid induced writhing in mice. The compounds synthesized were assuredly validated by means of Infrared, Nuclear Magnetic Resonance (1H and 13C), Gas Chromatography Mass Spectrophotometer and Elemental analysis. The synthesized compounds were tested for their antibacterial activity.Compounds 1,2 and 3 showed significant antibacterial activities. Discussion: Compound 1 was identified by the absence of methyl group and the presence of methyl group for compound 2. The test analysed compounds exhibited significant antibacterial activities. The compounds synthesized exhibited promising antibacterial activities against the tested organisms. Conclusion: The compounds have high antibacterial activities. Compound 2 has a higher activity compared to Compound 1 and 3. Compound 2 has a higher antibacterial against Escherichia coli, Klebsiella pneumonia and Pseudomonas aeuriginosa
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D, Priya, Srimathi R, and Anjana Gv. "SYNTHESIS AND EVALUATION OF SOME MANNICH BASES OF QUINAZOLINONE NUCLEUS." Asian Journal of Pharmaceutical and Clinical Research 11, no. 2 (February 1, 2018): 407. http://dx.doi.org/10.22159/ajpcr.2018.v11i2.22644.

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Objective: In the present work, a series of five Mannich bases of quinazolinone nucleus synthesized by treating quinazolinones with various aromatic amines.Methods: A series of Mannich bases of quinazolinone synthesized by refluxing quinazolinone with anthranilic acid, amine, and formaldehyde in ethanol. The chemical structures of synthesized compounds were confirmed by thin-layer chromatography using the suitable solvent system and characterized by melting point and IR. The compounds screened for their antibacterial activity and antioxidant activity.Results: Antioxidant activity of the synthesized compounds was done using 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals scavenging method. Compounds II and III showed values at 53% and 36%, respectively, when compared to that of standard ascorbic acid 24% at 10 μg/ml. Compounds II and IV showed excellent activity against Gram-negative organism Escherichia coli using ciprofloxacin as standard.Conclusion: All the synthesized compounds were screened for antimicrobial activity by cup plate by measuring inhibition zone using E. coli at a concentration range of 200–600 mcg/ml, and antioxidant activity was determined by DPPH method.
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Abdou, Ibrahim M., and Shaikha S. Al-Neyadi. "Synthesis of quinazolines and quinazolinones via palladium-mediated approach." Heterocyclic Communications 21, no. 3 (June 1, 2015): 115–32. http://dx.doi.org/10.1515/hc-2014-0181.

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AbstractQuinazoline derivatives have drawn attention in the field of heterocyclic chemistry because of their unique skeleton and interesting biological applications. This review summarizes the recent palladium-catalyzed reactions used to construct quinazoline and its related 4(3H)-quinazolinone analogues. The mechanisms of some Pd-catalyzed reactions are also discussed.
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Koketsu, Mamoru, Amol Sonawane, Yunnus Shaikh, and Dinesh Garud. "Synthesis of Isoquinoline-Fused Quinazolinones through Ag(I)-Catalyzed Cascade Annulation of 2-Aminobenzamides and 2-Alkynylbenzaldehydes." Synthesis 51, no. 02 (September 21, 2018): 500–507. http://dx.doi.org/10.1055/s-0037-1610910.

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A new route for the expedient synthesis of a specific regioisomer of isoquinoline-fused quinazolinones is reported. Silver(I)-catalyzed cascade cyclization of 2-aminobenzamides and 2-alkynylbenzaldehydes followed by in situ oxidation gives 12-butyl- or 12-aryl-6H-isoquinolino[2,1-a]quinazolin-6-ones in 69–91% yields. The structure of the isoquinoline-fused quinazolinone was confirmed by X-ray crystallography analysis.
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Dissertations / Theses on the topic "Quinazolinone synthesis"

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Stein, Tobias. "Radical synthesis of quinazolinone natural products." Thesis, Loughborough University, 2007. https://dspace.lboro.ac.uk/2134/34389.

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Investigations into radical and palladium(0) cyclisations onto the C-2 position of the 3H-quinazolin-4-one moiety have been made. This has led to the syntheses of a number of biologically active quinazolinone natural products using alkyl, heteroaryl and acyl radical cyclisations. The reactions proceeded via a homolytic aromatic substitution mechanism. As such, fully rearomatised products were recovered. A C-2 radical 3H-quinazolin-4-one building block was also prepared. This turned out to have only limited synthetic applications. Radical cyclisations onto aryl groups were carried out using this building block.
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Dai, Xuedong 1970. "Synthesis and applications of atropisomeric quinazolinone phosphine ligands." Thesis, Massachusetts Institute of Technology, 1998. http://hdl.handle.net/1721.1/47887.

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Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 1998.
Includes bibliographical references.
Several novel atropisomeric phosphine ligands have been synthesized and evaluated. The syntheses of 2-methyl-3-[2'-(diphenylphosphino)phenyl]-4(3H)- quinazolinone (la) and its methyl-substituted analogs lb and ic were achieved in good yield by coupling N-acetylanthranilic acid with the corresponding phosphinoanilines 4a-c. A practical resolution of ligands la-c was accomplished using the benzenesulfonylhydrazone derivative (10) of (1S)-(+)-camphorsulfonic acid as a novel resolving agent. Several catalytic reactions including palladium-catalyzed asymmetric allylic alkylation, phosphine-catalyzed [3+2] cycloaddition of N-tosylimines with 2,3- butadienoate, and asymmetric intramolecular Heck reaction were performed. The 2-methyl group of this ligand series could be activated into the olefin form in the presence of Rh(nbd)2C104. The rhodium complex was found to be able to catalyze conjugate addition of the Grignard reagent (n-BuMgBr) to enones. The synthesis of 3-[4',6'-dimethyl-2'-(diphenylphosphino)phenyl]-4(3H)- quinazolinone (id) was achieved by coupling 4H-3,1-benzoxazin-4-one (71) with 4,6- dimethyl-2-diphenylphosphinoaniline (4c). Ligand ld could be directly lithiated by lithium diisopropylamide (LDA). The hetero-substituted analogs le-g were synthesized in good yield by quenching the lithium anion of ligand id with electrophiles. Resolutions of ligands id and le were achieved using (-)-di-p-chloro-bis[(S)-dimethyl-(1- naphthylethyl)aminato-C 2 , N]dipalladium(II) (78) and (-)-di-ji-chloro-bis[(S)-dimethyl-(1- phenylethyl)aminato-C 2 , N]dipalladium(II) (7), respectively.
by Xuedong Dai.
Ph.D.
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Norrie, R. "The synthesis and reactions of sulphur analogues of deoxyvasicinone." Thesis, University of Abertay Dundee, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.233850.

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Lindgren, Anders. "Synthesis of Small Molecules Targeting ADP-Ribosyltransferases and Total Synthesis of Resveratrol Based Natural Products." Doctoral thesis, Umeå universitet, Kemiska institutionen, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-108010.

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Diphtheria Toxin-like ADP-Ribosyltransferases The Human ADP-ribosyl transferases (ARTDs) are a group of poorly studied enzymes which are believed to be involved in e.g. DNA repair, protein degradation, transcription regulation and cell death. Medicinal chemistry programmes aimed at developing selective inhibitors of these ARTDs were initiated. A suitable starting compound for one of these enzymes, ARTD3, was found by screening a library of NAD-mimics using a thermal shift assay. A virtual screening protocol was instead developed in order to find novel inhibitors of ARTD7, 8, and 10. The hit compounds were then further developed into selective inhibitors of the corresponding ARTDs by systematically varying different structural features using a combination of synthetic organic chemistry, computational chemistry and structural biology. Compounds were initially characterized using differential scanning fluorimetry which was later replaced with an enzymatic assay to obtain IC50 values. Biotinylated analogs were also synthesized in an attempt to develop an AlphaScreen assay. A selective ARTD3 inhibitor was ultimately identified and found to delay DNA repair in cells after γ-irradiation. These compounds are potentially valuable tools for elucidating the biological role of the poorly characterized ARTD-family of proteins. Total Synthesis of Resveratrol Based Natural Products The polyphenolic natural product (-)-hopeaphenol was found to inhibit the type III secretion system present in certain gram-negative bacteria. (-)-Hopeaphenol is a tetramer of resveratrol and in order to investigate whether the entire structure was essential for inhibition two resveratrol dimers, ε-viniferin and ampelopsin B, were synthesized using a flexible and divergent synthetic route. Highlights of the synthetic strategy include the use of cyclopropylmethyl protecting groups, allowing an acid mediated three-step-one-pot deprotection-epimerization-cyclization of an advanced intermediate to form ampelopsin B. All previously reported syntheses of these two natural products include a dimerization of resveratrol which severly limits the possibilities to synthesize structural analogs. This new strategy enables the synthesis of a wide variety of analogs to ε-viniferin and ampelopsin B.
Populärvetenskaplig sammanfattning Små molekyler för att identifiera proteiners funktion Vår arvsmassa innehåller cirka 24000 gener som i sin tur innehåller information för hur de tusentals proteiner vi är uppbyggda av ska framställas. Många läkemedel fungerar genom att en molekyl interagerar med ett av dessa proteiner och hämmar dess funktion för att på så sätt framkalla en önskad effekt. Vi vet dock inte vilken funktion många av våra proteiner fyller vilket ofta gör utvecklingen av nya läkemedel svår eller omöjlig. Den första delen av denna avhandling beskriver en grupp proteiner kallade ARTDs och hur små molekyler kan framställas och systematiskt förbättras för att till slut helt kunna slå ut vissa av dessa ARTDs. Genom att sedan studera vilka effekter detta medför kan man ta reda på vilken funktion proteinet fyller. På längre sikt skulle denna kunskap sedan kunna användas för att utveckla nya läkemedel genom att till exempel slå ut de proteiner som orsakar en sjukdom. Totalsyntes av naturprodukter Naturprodukter defineras inom kemin som naturligt förekommande molekyler som produceras av levande organismer. De kan hittas i allt från mikroorganismer och växter till djur och kan vara en del av deras ämnesomsättning, en restprodukt eller ha någon annan funktion, känd eller okänd. Människor, och i vissa fall även andra djur, har sedan urminnes tider ovetandes använt dessa molekyler för en mängd olika syften, som gifter, färgämnen eller läkemedel. Penicillin är en av de mest kända, men mer än hälften av de nya läkemedel som godkänts de senaste trettio åren bygger på naturprodukter eller har inspirerats av dessa. De fortsätter således att vara viktiga för utvecklingen av nya läkemedel trots att vi idag har möjligheten att utveckla sådana från grunden. Att framställa naturprodukter på konstgjord väg kallas totalsyntes och är ofta en mycket svår och tidskrävande process. Vanligtvis rör det sig om mycket stora och komplexa molekyler och det finns sällan ett uppenbart sätt att genomföra totalsyntesen. För att bättre klara av detta måste nya metoder utvecklas. Den andra delen av denna avhandling beskriver nya metoder för att framställa komplexa molekyler kallade polyfenoler. Målet var att dessa metoder skulle vara så pass flexibla att de även kan användas för att framställa nya polyfenoler som aldrig tidigare existerat men som har förbättrade egenskaper.
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Quevedo, Camilo E. "Design and synthesis of Quinazolinone-based libraries for inhibitation of Kinase activity and hit-to-lead optimisation of Wnt pathway inhibitors." Thesis, Institute of Cancer Research (University Of London), 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.510367.

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Jaeda, Mousa I. "The synthesis of 2-quinazolinones and homologues." Thesis, Aston University, 1985. http://publications.aston.ac.uk/12495/.

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Maiden, Tracy M. M. "C-H activation studies towards the synthesis of highly functionalised quinazolinones." Thesis, University of Sheffield, 2016. http://etheses.whiterose.ac.uk/16057/.

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Ozcan, Sevil. "Development Of New Synthetic Methodologies For The Synthesis Of Unusual Isocoumarin And Indole Derivatives:the Chemistry Of Homophthalic Acid." Phd thesis, METU, 2007. http://etd.lib.metu.edu.tr/upload/3/12608197/index.pdf.

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Many heterocyclic compounds containing nitrogen, oxygen and sulfur show wide range of physiological activities and their synthesis has always been attracted the interest of chemists. The aim of this research is to develop new synthetic methodologies leading to the synthesis of new derivatives of isocoumarines, indoles, isoquinolines, benzodiazepinones and quinazolines, which have been found to show important biological activities. Starting from homophthalic acid and bishomophthalic acid the corresponding acyl azides were proposed to be synthesized, which then would be used for the synthesis of various heterocycles. The proposed diazide from homophthalic was not formed due to the tendency of the ortho-positioned acid to undergo cyclization. Instead, new unusual benzochromen and isocoumarin derivatives have been synthesized in a single step, for which reasonable mechanisms have been proposed. The half ester produced from homophthalic acid was an important key compound for the synthesis of new highly substituted indole derivatives, which are expected to be biologically active. The diisocyanate derived from was synthesized directly from ortho-bromo xylene was treated with alcohols and hydrazine to produce seven membered rings. Instead of the intramolecular cyclization reaction, they underwent polymerization to form new polymers. Furthermore, new synthetic method for the synthesis of pyrazoles has been developed.
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Larraufie, Marie-Hélène. "Development of new radical cascades and multi-component reactions : application to the synthesis of nitrogen-containing heterocycles." Paris 6, 2011. http://www.theses.fr/2011PA066516.

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Le travail décrit dans ce manuscrit de thèse est consacré au développement de nouvelles méthodes radicalaires et organométalliques permettant la synthèse de différentes classes de polycycles azotés. Nous avons étudié des cascades impliquant le motif N-acylcyanamide. Des précurseurs de type alkyle ont permis la synthèse de quinazolinones naturelles. L’utilisation de précurseurs vinyliques a permis de mettre à jour un processus de migration original, qui apporte de nouveaux éléments pour la compréhension du mécanisme de substitution aromatique homolytique. Enfin des radicaux aminyles ont pu être engagés dans ces cascades, conduisant à la première synthèse radicalaire de guanidines. Conscients de la nécessité de trouver des alternatives vertes pour la génération de radicaux, nous nous sommes intéressés à la catalyse photoredox en lumière visible. Nous l’avons utilisée pour la photo-génération de radicaux à partir d’époxydes et d’aziridines. D’autre part, le système catalytique palladium/norbornene a été employé pour la synthèse efficace de phenanthridines à partir d’iodures d’aryles et d’amines benzyliques. L’utilisation d’amide benzyliques nous a permis de mettre à jour la première exception à l’effet ortho. Des calculs DFT ont rationnalisé l’influence de la chélation sur la sélectivité de l’élimination réductrice à partir de l’intermédiaire Pd(IV) impliqué
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Malecki, Natacha. "Conception et synthese de derives quinoleiniques et quinazoliniques inhibiteurs potentiels des topoisomerases i et ii." Lille 2, 2001. http://www.theses.fr/2001LIL2P251.

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Books on the topic "Quinazolinone synthesis"

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Jaeda, Mousa Ibrahim. The synthesis of 2-quinazolinones and homologues. Birmingham: University of Aston. Department of Pharmaceutical Sciences, 1985.

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Book chapters on the topic "Quinazolinone synthesis"

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Dangi, R. R., N. S. Chundawat, and K. L. Ameta. "Synthesis and Biological Evaluation of Some Quinazoline Heterocyclic Derivatives." In Green Chemistry: Synthesis of Bioactive Heterocycles, 393–412. New Delhi: Springer India, 2014. http://dx.doi.org/10.1007/978-81-322-1850-0_13.

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Ubale, Panchsheela Ashok, Amit Arvind Kamble, Maina Machindra Awatade, and Vasant Baburao Helavi. "Synthesis and Characterization of Copper(II), Cadmium(II) and Nickel(II) Complexes Containing 3-Amino-2-Methyl-4(3H)Quinazoline and Triphenylphosphine as Ligands." In Techno-Societal 2020, 955–63. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-69925-3_91.

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Bavetsias, Vassilios, Ann L. Jackman, Tim J. Thornton, Krzysztof Pawelczak, F. Thomas Boyle, and Graham M. F. Bisset. "Quinazoline Antifolates Inhibiting Thymidylate Synthase: Synthesis of γ-Linked Peptide and Amide Analogues of 2-Desamino-2-Methyl-N10-Propargyl-5,8-Dideazafolic Acid (ICI 198583)10-Propargyl-5,8-Dideazafolic Acid (ICI 198583)." In Advances in Experimental Medicine and Biology, 593–96. Boston, MA: Springer US, 1993. http://dx.doi.org/10.1007/978-1-4615-2960-6_121.

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E. Hashem, Heba. "Synthesis of Quinazoline and Quinazolinone Derivatives." In Quinazolinone and Quinazoline Derivatives. IntechOpen, 2020. http://dx.doi.org/10.5772/intechopen.89180.

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Mishra, Satyendra. "Quinazolinone and Quinazoline Derivatives: Synthesis and Biological Application." In Quinazolinone and Quinazoline Derivatives. IntechOpen, 2020. http://dx.doi.org/10.5772/intechopen.89203.

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Bhanudas Zangade, Sainath. "Quinazoline Based Synthesis of some Heterocyclic Schiff Bases." In Quinazolinone and Quinazoline Derivatives. IntechOpen, 2020. http://dx.doi.org/10.5772/intechopen.89871.

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Chiriţă, Cornel, Carmen Limban, Diana Camelia Nuţă, Emil Ştefănescu, Simona Negreş, Cristina Elena Zbârcea, Cristina Daniela Marineci, et al. "Synthesis and Pharmacological Research Regarding New Compounds with Quinazolin-4-One Structure." In Quinazolinone and Quinazoline Derivatives. IntechOpen, 2020. http://dx.doi.org/10.5772/intechopen.89164.

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Y. Abbas, Samir. "4(3H)-Quinazolinone Derivatives: Syntheses, Physical Properties, Chemical Reaction, and Biological Properties." In Quinazolinone and Quinazoline Derivatives. IntechOpen, 2020. http://dx.doi.org/10.5772/intechopen.90104.

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Harris, P. A. "10.24.2 Product Subclass 2: Pyrimido[1,2-a]indoles and Related Benzo-Fused Ring Systems." In Science of Synthesis: Knowledge Updates 2021/3. Stuttgart: Georg Thieme Verlag KG, 2021. http://dx.doi.org/10.1055/sos-sd-110-01955.

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AbstractMethods for the synthesis of pyrimido[1,2-a]indoles and the related indolo[1,2-a]quinazoline and indolo[2,1-b]quinazoline ring systems are reviewed in this chapter. Although limited reports have been published to date, a variety of differing approaches to these heterocycles have been described.
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Sato, R., and T. Kimura. "Synthesis by Selenation of Quinazolinones." In Sulfur, Selenium, and Tellurium, 1. Georg Thieme Verlag KG, 2008. http://dx.doi.org/10.1055/sos-sd-039-01451.

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Conference papers on the topic "Quinazolinone synthesis"

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Al-Majedy, Yasmien, Ahmed Al-Amiery, and Redha Al-Bayati. "Novel quinazolinone derivatives: Synthesis and Antimicrobial Activity." In The 14th International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 2010. http://dx.doi.org/10.3390/ecsoc-14-00413.

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Rammohan, Aluru, and Grigory V. Zyryanov. "Synthesis and characterization of 1,2,3-triazole integrated quinazolinone derivatives." In PROCEEDINGS OF INTERNATIONAL CONFERENCE ON RECENT TRENDS IN MECHANICAL AND MATERIALS ENGINEERING: ICRTMME 2019. AIP Publishing, 2020. http://dx.doi.org/10.1063/5.0018182.

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Maleki, Ali, Jamal Rahimi, and Razieh Firouzi Haji. "Green synthesis of quinazolinone derivatives by using a recyclable heteropoly acid catalyst." In The 21st International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 2017. http://dx.doi.org/10.3390/ecsoc-21-04722.

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Laddha, Sachin, and Satyendra Bhatnagar. "Rapid microwave-assisted solution phase synthesis of 6, 8-disubstituted- 2-phenyl-3-(substituted-benzothiazole-2-yl) – 4-[3H]-quinazolinone as novel anticonvulsants." In The 10th International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 2006. http://dx.doi.org/10.3390/ecsoc-10-01438.

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Maleki, Ali, and Nakisa Ghamari. "A three-component one-pot procedure for the synthesis benzimidazolo-quinazolinone derivatives in the presence of chitosan-supported metal nanocomposite as a green and reusable catalyst." In The 17th International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 2013. http://dx.doi.org/10.3390/ecsoc-17-a034.

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Naimi-Jamal, Mohammad Reza, and Maryam karimi. "A simple, convenient three component one-pot procedure for the synthesis of benzimidazolo-quinazolinone derivatives in the presence Silica-based sulfonic acid (MCM-41-SO3H): a efficient and practical catalyst." In The 19th International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 2015. http://dx.doi.org/10.3390/ecsoc-19-a001.

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Dolzhenko, Anton, Anna Dolzhenko, and Wai-Keung Chui. "Reaction of 2-guanidino-4-quinazolinone with arylaldehydes." In The 10th International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 2006. http://dx.doi.org/10.3390/ecsoc-10-01382.

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Guerreiro Souzedo, Gabriela, LJUBICA TASIC, and Caio Henrique Nasi De Barros. "Synthesis of Quinazoline Derivatives for Adenosine Kinase Inhibition." In XXV Congresso de Iniciação Cientifica da Unicamp. Campinas - SP, Brazil: Galoa, 2017. http://dx.doi.org/10.19146/pibic-2017-78452.

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Suong, Lien Kieu, Vo Phung Nguyen, and Trinh Thi Phuong Lan. "ANTI-CONVULSIVE ACTIVITY OF NL197, A DERIVATIVE FROM 4(3H)QUINAZOLINON ON CHEMICAL INDUCED SEIZURE MICE." In The 13th International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 2009. http://dx.doi.org/10.3390/ecsoc-13-00215.

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Chatterjee, Rana, Subhankar Sarkar, Sougata Santra, Grigory V. Zyryanov, and Adinath Majee. "Brønsted acidic ionic liquid-catalyzed one-pot synthesis of 4(3H)-quinazolinones under solvent-free conditions." In PROCEEDINGS OF INTERNATIONAL CONFERENCE ON RECENT TRENDS IN MECHANICAL AND MATERIALS ENGINEERING: ICRTMME 2019. AIP Publishing, 2020. http://dx.doi.org/10.1063/5.0018520.

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