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Relevant bibliographies by topics / Quinoline carboxylic acid

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Academic literature on the topic 'Quinoline carboxylic acid'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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Journal articles on the topic "Quinoline carboxylic acid"

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Öhlinger, Stefan Holger. "AN EFFICIENT SYNTHESIS OF β-(3-QUINOLINYL)-α-ALANINE". SOUTHERN BRAZILIAN JOURNAL OF CHEMISTRY 17, № 17 (2009): 1–8. http://dx.doi.org/10.48141/sbjchem.v17.n17.209.4_2009.pdf.

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A convenient synthesis for β-(3-quinolinyl)-α-alanine (4) is presented. Condensation of 2-chloro-3-chloromethylquinoline (5) with diethyl acetamidomalonate (2) gave high yield of diethyl 2-acetylamino-2-(2-chloro-3-quinolinylmethyl)- propanedionate (6), which was dehalogenated in the presence of ammonium formate and palladium/charcoal. Diethyl 2-acetamido-2-(3-quinolinylmethyl)-malonate (3) was easily converted to the amino acid. The condensation reaction between 2 and 6 is also useful for the construction of (1H)-2,3-dihydropyrrolo[2,3-b]quinoline-2,2-bis(carboxylic acid) and pyrrolo[2,3-b]qu

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Gaber, Ahmed, Walaa F. Alsanie, Majid Alhomrani, Abdulhakeem S. Alamri, Ibrahim M. El-Deen, and Moamen S. Refat. "Synthesis and Characterization of Some New Coumarin Derivatives as Probable Breast Anticancer MCF-7 Drugs." Crystals 11, no. 5 (2021): 565. http://dx.doi.org/10.3390/cryst11050565.

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This study aimed to synthesize quinolinone derivatives and investigate their cytotoxic activity. The compound 1-azacoumarin-3-carboxylic acid (2-oxo-1H-quinoline-3-carboxylic acid) was obtained via the cyclocondensation of 2-hydroxybenzaldehyde with diethyl malonate in base catalyst to give ethyl coumarin-3-carboxylate, followed by the ammonolysis of ester (ethyl coumarin-3-carboxylate) with ammonia in the presence of anhydrous potassium carbonate. Treatment of 2-oxo-1H-quinoline-3-carboxylic acid with acetic anhydride, cinnamaldehyde, cinnamic acid and methyl 5-phenyl-2-cyano-2,4-pentadienoat

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Dobson, A. J., and R. E. Gerkin. "Quinoline-4-carboxylic Acid." Acta Crystallographica Section C Crystal Structure Communications 54, no. 12 (1998): 1883–85. http://dx.doi.org/10.1107/s0108270198009585.

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Yadav, Pradeep, and Y. C. Joshi. "Synthesis and Spectral Study of Novel Norfloxacin Derivatives." E-Journal of Chemistry 5, s2 (2008): 1154–58. http://dx.doi.org/10.1155/2008/357073.

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Reaction of [1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-quinolone-3-carboxylic acid (norfloxacin) with thiazole / benzothiazole diazonium chloride to get new piperazine substituted norfloxacin derivative. These norfloxacin derivatives were further condensed with variousβ-diketone to get novel acid derivatives of 1-Ethyl-6-fluoro-4-oxo-7- [4 (thiazol-2-yldiazenyl)-piperzin-1-yl]-1,4-dihydro-quinoline-3-carboxylic acid (6a-e) and 7-(4-(benzo[d]thiazol-2-yldiazenyl)piperazin-1-yl)-1-ethyl-6-fluoro-4-oxo-1, 4-dihydroquinoline-3-carboxylic acid (6 f-j). Structures of these compounds were

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Gauvreau, D., I. E. Swift, and M. J. Waring. "Studies on antibiotic biosynthesis by protoplasts and resting cells of Streptomyces echinatus. Part II. Effect of chromophore precursors." Canadian Journal of Microbiology 32, no. 5 (1986): 363–72. http://dx.doi.org/10.1139/m86-071.

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Washed cell and protoplast suspensions from Streptomyces echinatus A8331, which produces the quinoxaline antibiotic echinomycin, have been used to study the effects of analogues of the natural chromophore upon antibiotic biosynthesis. Addition of quinoline-2-carboxylic acid caused a decrease in the labelling of echinomycin from L-[methyl-14C]methionine and an increase in labelled chloroform-extractable material. Quinoxaline-2-carboxylic acid increased the incorporation of radioactivity into both fractions. Thieno[3,2-b]pyridine-5-carboxylic acid, 6-methylquinoline-2-carboxylic acid, and quinol

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Ng, Seik Weng. "(Quinoline-2-carboxylato-κO)(quinoline-2-carboxylic acid-κO)bis(quinoline-2-carboxylic acid-κ2N,O)potassium". Acta Crystallographica Section E Structure Reports Online 66, № 8 (2010): m948. http://dx.doi.org/10.1107/s1600536810027510.

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Abd El-Aal, Hassan A. K., and Talaat I. El-Emary. "Synthesis of Tetracyclic Fused Quinolines via a Friedel–Crafts and Beckmann Ring Expansion Sequence." Australian Journal of Chemistry 72, no. 12 (2019): 945. http://dx.doi.org/10.1071/ch19363.

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An efficient protocol for the construction of tetracyclic fused quinolines (pyrazole-fused azepino-, azocino-, and azonino[3,2-b]quinolinones) via consecutive Friedel–Crafts and Beckmann reactions has been developed. The key steps in the syntheses of these new molecular scaffolds involve acid-mediated cyclization of 2-(pyrazol-3-yl)quinoline based carboxylic acids 6a–c, 8, and 12 to ketones 13a–e, followed by Beckmann rearrangements of the corresponding oximes 14a–e to provide the tetracyclic-fused quinoline skeletons 15a–e. Structures of synthesised compounds without stereochemical implicatio

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Abd El-Aal, Hassan A. K., and Talaat I. El-Emary. "Corrigendum to: Synthesis of Tetracyclic Fused Quinolines via a Friedel–Crafts and Beckmann Ring Expansion Sequence." Australian Journal of Chemistry 72, no. 12 (2019): 990. http://dx.doi.org/10.1071/ch19363_co.

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An efficient protocol for the construction of tetracyclic fused quinolines (pyrazole-fused azepino-, azocino-, and azonino[3,2-b]quinolinones) via consecutive Friedel–Crafts and Beckmann reactions has been developed. The key steps in the syntheses of these new molecular scaffolds involve acid-mediated cyclization of 2-(pyrazol-3-yl)quinoline based carboxylic acids 6a–c, 8, and 12 to ketones 13a–e, followed by Beckmann rearrangements of the corresponding oximes 14a–e to provide the tetracyclic-fused quinoline skeletons 15a–e. Structures of synthesised compounds without stereochemical implicatio

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Zacharopoulos, Nikolaos, Gregor Schnakenburg, Eleni I. Panagopoulou, Nikolaos S. Thomaidis, and Athanassios I. Philippopoulos. "Pyridine–Quinoline and Biquinoline-Based Ruthenium p-Cymene Complexes as Efficient Catalysts for Transfer Hydrogenation Studies: Synthesis and Structural Characterization." Molecules 30, no. 14 (2025): 2945. https://doi.org/10.3390/molecules30142945.

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Searching for new and efficient transfer hydrogenation catalysts, a series of new organometallic ruthenium(II)-arene complexes of the formulae [Ru(η6-p-cymene)(L)Cl][PF6] (1–8) and [Ru(η6-p-cymene)(L)Cl][Ru(η6-p-cymene)Cl3] (9–11) were synthesized and fully characterized. These were prepared from the reaction of pyridine–quinoline and biquinoline-based ligands (L) with [Ru(η6-p-cymene)(μ-Cl)Cl]2, in 1:2 and 1:1, metal (M) to ligand (L) molar ratios. Characterization includes a combination of spectroscopic methods (FT-IR, UV-Vis, multi nuclear NMR), elemental analysis and single-crystal X-ray c

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Fang, Guiqian, Hao Wang, Zhancun Bian, et al. "2-(4-Boronophenyl)quinoline-4-carboxylic acid derivatives: Design and synthesis, aggregation-induced emission characteristics, and binding activity studies for D-ribose with long-wavelength emission." Journal of Chemical Research 44, no. 3-4 (2019): 152–60. http://dx.doi.org/10.1177/1747519819893642.

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Long-wavelength fluorescent sensors with large Stokes shifts show useful applications in chemical biology and clinical laboratory diagnosis. We have recently reported [4-(4-{[3-(4-boronobenzamido)propyl]carbamoyl}quinolin-2-yl)phenyl]boronic acid that can selectively recognize d-ribose in a buffer solution of pH 7.4. However, the short emission wavelength (395 nm) and aggregation-caused quenching effect are not conducive to applications as a sensor. Novel diboronic acid compounds are synthesized using 2-(4-boronophenyl)quinoline-4-carboxylic acid as the building block and p-phenylenediamine as

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Dissertations / Theses on the topic "Quinoline carboxylic acid"

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Dobson, Allison J. "X-ray diffraction investigations of quinoline and amino carboxylic acids /." The Ohio State University, 1998. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487949836206992.

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RUHLAND-FRITSCH, BEATRICE. "Synthese et etude pharmacologique de derives benzeniques d'analogues du gaba." Université Louis Pasteur (Strasbourg) (1971-2008), 1989. http://www.theses.fr/1989STR13056.

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Wang, Yi-Ju, та 王以如. "具關節炎用藥潛能之2-Quinoline-4-carboxylic Acid類似物之合成". Thesis, 2011. http://ndltd.ncl.edu.tw/handle/59577328372717768347.

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Zshuang, Shi-Hong, and 莊仕弘. "Synthesis and anti-cancer activity of 2–phenyl-4-quinolone-3-carboxylic acid derivatives." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/13961032007923274753.

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碩士<br>中國醫藥大學<br>藥物化學研究所碩士班<br>95<br>In our continuing work aimed at the discovery and development of novel anticancer agents, 2-(3-fluorophenyl)-6-methoxy-4-quinolone-3- carboxylic acid was identified as a promising anticancer drug candidate. Encouraged by the preliminary results, 2-(3-fluorophenyl)-6- methoxy-4-quinolone-3-carboxylic acid was used as a lead compound, a series of 2-(2,3-substituted phenyl)-6,7-substituted 4-quinolone-3- methanols (42 – 55), 2-(2,3-substituted phenyl)-6,7-substituted 4-quinolone-3-carbaldehydes (56–58), 2-(2,3-substituted phenyl)-6, 7-substituted 4-quinolo

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Ya-Ling, Fang, and 方亞齡. "Synthesis and Cytotoxicity of 2',6,7-Substituted 2-Phenyl-4-quinolone-3-carboxylic acid Derivatives." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/08490728672626489748.

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碩士<br>中國醫藥學院<br>藥物化學研究所<br>91<br>In a previous paper, a series of 3',6-substituted 2-phenyl-4-quinolone-3-carboxylic acids were synthesized, and their cytotoxicity was evaluated. Some of 3',6-substituted 2-phenyl-4-quinolone-3-carboxylic acids showed significant activity. Encouraged by the initial result, 2',6,7-substituted 2-phenyl-4-quinolone-3-carboxylic acids were synthesized. Reaction of substituted anilines 1-5 with substituted benzoyl chlorides 6-10 yielded the corresponding benzamides 11-24. Chlorination of compounds 11-24 with PCl5 afforded the carboximidoyl chlorides that

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Tsai, Shang-Yuan, and 蔡尚元. "Physicochemical properties and dissolution improvements of 9,10-anthraquinone-2-carboxylic acid and 2-phenyl-4-quinolone." Thesis, 1996. http://ndltd.ncl.edu.tw/handle/22625165088364159839.

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博士<br>中國醫藥學院<br>藥物化學研究所<br>84<br>9,10-Anthraquinone-2-carboxylic acid ( AQCA ) is a　quinone derivative and 2-phenyl-4-quinolone ( PQO ) is a　quinolone deri-vative. AQCA was found to posses antiallergic　activity; PQO was shown to demonstrate anticancer and　antiarrhythmic effects. In this study, the physicochemical properties of AQCA and PQO were investigated. Their solid dispersions or ground mixtures were prepared and in-vitro dissolution tests were carried out to investigate the improvement on dissolution. 　　By using FT-IR, differential　scanning calorimetry and pow-der X-ray diffractometry, A

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Yun, Lai Ya, and 賴雅韻. "Part I . Synthesis and Activities of Anticancer, Anti-platelet, Anti-allergy and Anti-inflammatory of 3',6-Substituted 2-Phenyl-4-quinolone-3-carboxylic acid derivatives Part II Activities of Anticancer and Anti-Helicobacter pylori of Gingerdione and." Thesis, 2002. http://ndltd.ncl.edu.tw/handle/08949263397641876018.

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博士<br>中國醫藥學院<br>藥物化學研究所<br>90<br>Abstract The purpose of this study was to search novel antimitotic agents. There were two parts in the thesis. Firstly, the target compounds, 3',6 substituted 2-phenyl-4- quinolone-3-carboxylic acids and their salts were successfully prepared to improve the solubility of 2-phenyl-4-quinolones, of which many compounds were potent antimitotic agents. They were preliminary offered to evaluate the activities of cell proliferation, including MCF, HOS, KB, KB-VIN, SK-ME-L, HCT-8, PC-3, IA9, HT-29 cell lines. Among them, 3'-fluoro-6-methoxy-2-phenyl-4-quino

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Book chapters on the topic "Quinoline carboxylic acid"

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Soni, Vatsala, Meenakshi Sharma, Vaishali Soni, and Shiv Lal Soni. "Exploration of Newer Possibilities to the Synthesis of Diazepine and Quinoline Carboxylic Acid Substituted Analogues of Benzothiazolo Condensed Oxocarbazoles and Oxoazacarbazoles of Medicinal Interest." In Challenges and Advances in Chemical Science Vol. 1. Book Publisher International (a part of SCIENCEDOMAIN International), 2021. http://dx.doi.org/10.9734/bpi/cacs/v1/2264f.

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Conference papers on the topic "Quinoline carboxylic acid"

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Pattanayak, Subrat Kumar. "Quantum chemical study on the NLO and NBO properties of 4-hydroxy quinoline-2-carboxylic acid." In 2ND INTERNATIONAL CONFERENCE ON CONDENSED MATTER AND APPLIED PHYSICS (ICC 2017). Author(s), 2018. http://dx.doi.org/10.1063/1.5032823.

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