Relevant bibliographies by topics / Quinoline derivative

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Quinoline derivative'

Author: Grafiati
Published: 4 June 2021
Last updated: 26 July 2025

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Journal articles on the topic "Quinoline derivative"

1

Shoji, Taku, Mutsumi Takeuchi, Mayumi Uda, et al. "Synthesis of Azuleno[2,1-b]quinolones and Quinolines via Brønsted Acid-Catalyzed Cyclization of 2-Arylaminoazulenes." Molecules 28, no. 15 (2023): 5785. http://dx.doi.org/10.3390/molecules28155785.

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Quinolone and quinoline derivatives are frequently found as substructures in pharmaceutically active compounds. In this paper, we describe a procedure for the synthesis of azuleno[2,1-b]quinolones and quinolines from 2-arylaminoazulene derivatives, which are readily prepared via the aromatic nucleophilic substitution reaction of a 2-chloroazulene derivative with several arylamines. The synthesis of azuleno[2,1-b]quinolones was established by the Brønsted acid-catalyzed intramolecular cyclization of 2-arylaminoazulene derivatives bearing two ester groups at the five-membered ring. The halogenat
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Rogerio, Kamilla Rodrigues, Cedric Stephan Graebin, Luiza Helena Pinto Domingues, et al. "Novel Quinolinyl-pyrrolo[3,4-d]pyrimidine-2,5-dione Derivatives Against Chloroquine-resistant Plasmodium falciparum." Current Topics in Medicinal Chemistry 20, no. 2 (2020): 99–110. http://dx.doi.org/10.2174/1568026619666191019100711.

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Introduction: In this work DHPMs were combined with the quinoline nucleus to obtain new quinolinyl-pyrrolo[3,4-d]pyrimidine-2,5-dione compounds with improved antiplasmodial activity as well as decreased cytotoxicity. Nineteen quinolinyl-pyrrolo[3,4-d]pyrimidine-2,5-dione derivatives connected by a linker group to quinolone ring moieties with different substituents were synthesized and assayed against P. falciparum. Materials and Methods: Nineteen quinolinyl-pyrrolo[3,4-d]pyrimidine-2,5-dione derivatives connected by a linker group to quinoline ring moieties with different substituents were syn
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R. Patel,, Dr Haresh. "An Application of Catalytic and Antimicrobial activity of Europium rare metal complex with Quinoline derivative." International Scientific Journal of Engineering and Management 04, no. 06 (2025): 1–9. https://doi.org/10.55041/isjem04437.

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Abstract: The combination of some rare metal ions with biologically important Quinoline derivative ligand to form coordination compound is an important area of current research. Less explored biologically important, Quinoline derivative ligand is allowed to react with solution of some rare metal perchlorates and attempt has been made to synthesize solid Quinoline derivative complexes. These Quinoline derivative complexes are subjected to U.V-Visible spectroscopy, IR spectroscopy, mass spectra, TGA analysis, elemental analysis etc. these complexes are used to study whether they possess catalyti
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Bremner, JB, та W. Jaturonrusmee. "Manganese(III) Acetate-Induced Formation of a Fused, Chloro-Substituted β-Lactam Derivative From a Chloroacetamide". Australian Journal of Chemistry 43, № 8 (1990): 1461. http://dx.doi.org/10.1071/ch9901461.

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Reaction of 1-chloroacetyl-5-methoxy-2,3-dihydro-1H-dibenzo[de,h]quinoline (1) with manganese(III) acetate in acetic acid at 50° gave the novel fused spiro derivative 11-chloro-4-methoxy-1,2-dihydro-6H-azeto[2,1-f]dibenzo[de,h]quinoline-6,12(11H)-dione (6) in 21% yield, together with 5-methoxy-7H-dibenzo[de,h]quinolin-7-one (3), 5-methoxy-2,3-dihydro-7H-dibenzo[de,h]quinolin-7-one (4), and 1- chloroacetyl-5-methoxy-2,3-dihydro-1H-dibenzo[de,h]-quinolin-7-yl ethanoate (5) in 1, 3 and 44% yields respectively. Compound (5) was shown to be a precursor of (3), (4) and (6).
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Wantulok, Jakub, Marcin Szala, Andrea Quinto, et al. "Synthesis, Electrochemical and Spectroscopic Characterization of Selected Quinolinecarbaldehydes and Their Schiff Base Derivatives." Molecules 25, no. 9 (2020): 2053. http://dx.doi.org/10.3390/molecules25092053.

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A new approach to the synthesis of selected quinolinecarbaldehydes with carbonyl groups located at C5 and/or in C7 positions is presented in this paper in conjunction with spectroscopic characterization of the products. The classical Reimer-Tiemann, Vilsmeier-Haack and Duff aldehyde synthesis methods were compared due to their importance. Computational studies were carried out to explain the preferred selectivity of the presented formylation transformations. A carbene insertion reaction based on Reimer-Tiemann methodology is presented for making 7-bromo-8-hydroxyquinoline-5-carbaldehyde. Addit
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Akhigbe, Joshua, Michael Luciano, Adewole O. Atoyebi, Steffen Jockusch, and Christian Brückner. "Quinoline-annulated porphyrin platinum complexes as NIR emitters." Journal of Porphyrins and Phthalocyanines 24, no. 01n03 (2020): 386–93. http://dx.doi.org/10.1142/s1088424619501256.

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The platinum(II) complexes of known quinoline-annulated porphyrins were prepared and spectroscopically characterized. Their optical properties (UV-vis absorption and phosphorescence spectra and phosphorescence lifetimes) were recorded and contrasted against their 2,3-dioxoporphyrin precursor platinum(II) complex. The absorbance and emission spectra (in EtOH glass at 77 K) of the quinoline-annulated porphyrins fall within the NIR optical window of tissue, ranging, depending on the derivative, between [Formula: see text]950 and 1200 nm. The much red-shifted optical spectra, when compared to thei
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Almansour, Abdulrahman I., Natarajan Arumugam, Saradh Prasad, et al. "Investigation of the Optical Properties of a Novel Class of Quinoline Derivatives and Their Random Laser Properties Using ZnO Nanoparticles." Molecules 27, no. 1 (2021): 145. http://dx.doi.org/10.3390/molecules27010145.

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Quinoline Schiff bases display potential applications in optoelectronics and laser fields because of their unique optical properties that arise from extensive delocalization of the electron cloud, and a high order of non-linearity. In this context, a new class of conjugated quinoline-derivative viz. N-(quinolin-3-ylmethylene)anilines were synthesized from 2-hydroxyquinoline-3-carbaldehyde in two good yielding steps. The ability of these imines to accept an electron from a donor is denoted by their electron acceptor number and sites, which is calculated using density functional theory (DFT). Th
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Yadav, Pradeep, and Y. C. Joshi. "Synthesis and Spectral Study of Novel Norfloxacin Derivatives." E-Journal of Chemistry 5, s2 (2008): 1154–58. http://dx.doi.org/10.1155/2008/357073.

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Reaction of [1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-quinolone-3-carboxylic acid (norfloxacin) with thiazole / benzothiazole diazonium chloride to get new piperazine substituted norfloxacin derivative. These norfloxacin derivatives were further condensed with variousβ-diketone to get novel acid derivatives of 1-Ethyl-6-fluoro-4-oxo-7- [4 (thiazol-2-yldiazenyl)-piperzin-1-yl]-1,4-dihydro-quinoline-3-carboxylic acid (6a-e) and 7-(4-(benzo[d]thiazol-2-yldiazenyl)piperazin-1-yl)-1-ethyl-6-fluoro-4-oxo-1, 4-dihydroquinoline-3-carboxylic acid (6 f-j). Structures of these compounds were
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Bonyad, Ali Moin. "Synthesis of Chalcones from Acetone and tetrazole and 2-acetyl naphthalene Assisted by Microwave." Engineering and Technology Quarterly Reviews 3, no. 1 (2020): 16–22. https://doi.org/10.5281/zenodo.3686827.

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In the present study, we understood the total synthesis one chalcone derivative via Claisen-Schmidt condensation of the respective aldehydes and ketones using Microwave assisted irradiation method. In the microwave environment, chemical reactions usually proceed faster and give higher yields with fewer by- products. In the synthesis, a common aldehyde namely tetrazolo {1, 5-a} quinoline-4-carbaldehyde was used while the ketones used were respectively acetone, 2- acetyl Naphthalene. The Chalcone synthesised from Tetrazolo {1, 5-a} quinolone-4-carbaldehyde and acetone was 4-(tetrazolo {1, 5-a} q
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Rádl, Stanislav, and Viktor Zikán. "Synthesis of 1,2, and 9-methyl derivatives of 4,9-dihydro-6-methoxy-3-methyl-4-oxo-1H(2H)-pyrazolo[3,4-b]quinoline and 4,9-dihydro-6-hydroxy-3-methyl-4-oxo-1H(2H)-pyrazolo[3,4-b]quinoline and their antiviral activity." Collection of Czechoslovak Chemical Communications 52, no. 3 (1987): 788–92. http://dx.doi.org/10.1135/cccc19870788.

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The paper describes syntheses of 4,9-dihydro-6-methoxy-3-methyl-4-oxo-1H(2H)-pyrazolo[3,4-b]quinoline (Ia), its 1-methyl derivative (Ic), 1,9-dimethyl derivative (Ie), 2-methyl derivative (IIa), and 2,9-dimethyl derivative (IIc). Demethylation of these compounds with hydrobromic acid afforded 4,9-dihydro-6-hydroxy-3-methyl-4-oxo-1H(2H)-pyrazolo[3,4-b]quinoline (Ib), its 1-methyl derivative (Id), 1,9-dimethyl derivative (If), 2-methyl derivative (IIb), and 2,9-dimethyl derivative (IId) respectively. 4,9-Dihydro-6-hydroxy-3,9-dimethyl-4-oxo-1H-pyrazolo[3,4-b]quinoline (Ig) was prepared by demeth
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Dissertations / Theses on the topic "Quinoline derivative"

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Ding, Ying. "Gap junction enhancer as an anti-cancer agent via GJIC-independent and -dependent pathways." Diss., Kansas State University, 2013. http://hdl.handle.net/2097/15705.

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Doctor of Philosophy<br>Department of Biochemistry and Molecular Biophysics<br>Thu Annelise Nguyen<br>Gap junctions (GJ) are intercellular channels connecting adjacent cells, allowing small molecules to transport between cells, thereby maintaining all homeostasis. Loss of gap junctional intercellular communication (GJIC) and/or connexins, the gap junction proteins, is a hallmark of cancer. Restoration of GJIC and/or increase of connexin expression have been related to the reduction of tumorigenesis. Connexins have been reported as tumor suppressors due to both GJIC-independent and -dependent m
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Taylor, David Lawrence. "The Reverse Vilsmeier route to quinolinium salts and derivatives." Thesis, University of Sunderland, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.294163.

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Haddad, Jalal. "Synthesis and chemistry of some quinoline-5,8-diones." Virtual Press, 1994. http://liblink.bsu.edu/uhtbin/catkey/917048.

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The synthesis of several 7-substituted analogs of 2-methylquinoline-5,8-dione and their chemistry are described. In this investigation the following compounds were prepared.5,7-Diformamido-8-hydroxy-2-methylquinoline (207), 7-formamido-2methylquinoline-5,8-dione (199), 7-acetamido-2-methylquinoline-5,8-dione (6), 7-isobutyramido-2-methylquinoline-5,8-dione (200), 7-amino-2-methylquinoline-5,8-dione (210), 7-amino-6-chloro-2-methylquinoline-5,8-dione (213), 7-methoxy-2-methylquinoline5,8-dione (214), 7-ethoxy-2-methylquinoline-5,8-dione (215), 7-isopropyloxy-2methylquinoline-5,8-dione (216), 7-
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Klaas, Phindile Jonathan. "Novel approaches to the synthesis of quinoline derivatives." Thesis, Rhodes University, 2001. http://hdl.handle.net/10962/d1004751.

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The investigation has been concerned with the application of the Baylis-Hillman methodology to the synthesis of quinoline derivatives. An extensive range of novel Baylis-Hillman products has been prepared, typically in moderate to excellent yields, by condensing 2-nitrobenzaldehyde derivatives with various vinyl ketones and acrylic esters in the presence of diazabicyclo[2.2.2]octane (DABCO). Reduction of the nitro group in the Baylis-Hillman products was effected by catalytic hydrogenation in ethanol using a 10% palladium-on-carbon catalyst to afford quinoline, quinoline-N-oxide and quinolone
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Pakade, Vusumzi Emmanuel. "Application of the Baylis-Hillman reaction in the preparation of quinoline derivatives." Thesis, Rhodes University, 2006. http://hdl.handle.net/10962/d1007669.

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The reaction of various 2-nitrobenzaldehyde derivatives with methyl vinyl ketone (MVK) in the presence of 1,4-diazabicyclo[2.2.2]octane (DABCO) has afforded the Baylis-Hillman adducts in moderate to good yield. Dissolution of the catalyst in the solvent before the addition of the aldehyde was observed to improve the yield. Reduction of the Baylis-Hillman adducts was effected by catalytic hydrogenation using a 10% palladium-on- carbon catalyst in ethanol to give quinoline and quinoline-N-oxide derivatives and, in some cases, acyclic reduction products. All products were characterised using NMR
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Loke, P. L. "Chemoenzymatic and chemical synthesis of enantiopure quinoline derivatives and alkaloids." Thesis, Queen's University Belfast, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.273295.

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Sharma, A. K. "Studies towards antitumor quinoline derivatives and development of useful synthetic methodologies." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 2001. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/2319.

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Kgokong, Joseph Lebese. "Trifluoromethyl-substituted quinoline and tetrazole derivatives :design, synthesis, antimalarial activity and cytotoxicity / Joseph L. Kgokong." Thesis, North-West University, 2008. http://hdl.handle.net/10394/3732.

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Malaria is a complex parasitic disease caused by the Plasmodium falciparum. It has been found to be responsible for the death of many people particularly in under-developed and developing countries. For many years chloroquine and quinine have been the mainstay of therapy for this disease. The research on new therapies against malaria have been hampered by factors such as the development of resistance against these and some of the new drugs or combinations thereof, the lack of adequate knowledge on the exact causes and mechanisms of resistance to the drugs and their mode of action, together wit
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Tukulula, Matshawandile. "The design and synthesis of novel HIV-1 protease inhibitors." Thesis, Rhodes University, 2009. http://eprints.ru.ac.za/1563/.

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Lee, Yi-Chen. "Studies towards the development of novel HIV-1 integrase inhibitors." Thesis, Rhodes University, 2010. http://hdl.handle.net/10962/d1005022.

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The project has focused on the preparation of several series of compounds designed as potential HIV-1 integrase inhibitors. Various 2-nitrobenzaldehydes have been reacted with two activated alkenes, methyl vinyl ketone (MVK) and methyl acrylate, under Baylis-Hillman conditions to afford α-methylene-β-hydroxylalkyl derivatives in moderate to excellent yields. The reactions were conducted using the tertiary amine catalysts, 1,4-diazabicyclo[2.2.2]octane(DABCO) or 3-hydroxyquinuclidine (3-HQ) with chloroform as solvent, and yields were optimised by varying the catalyst, reagent concentrations and
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Books on the topic "Quinoline derivative"

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W, Stone T., ed. Quinolinic acid and the kynurenines. CRC Press, 1989.

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Jokela, Reija. Indolo(2.3-a)quinolizine and n-methylpiperidine derivatives: Synthetic methods and stereochemical considerations. Suomalainen Tiedeakatemia, 1985.

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Singh, Rajesh Kumar, ed. Key Heterocyclic Cores for Smart Anticancer Drug–Design Part I. BENTHAM SCIENCE PUBLISHERS, 2022. http://dx.doi.org/10.2174/97898150400741220101.

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This book provides an update on heterocyclic compounds that serve as key components of anti-cancer agents administered in pre-clinical settings. Many of the compounds highlighted in the book are being actively investigated for the bioactive properties against a range of cancer cell lines. There is potential for heterocyclic compounds to design agents that can target specific molecules to treat different types of cancers. Chapters are contributed by experts in pharmaceutical chemistry and are written to give a general overview of the topic to readers involved in all levels of research and decis
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Mahiou, Belaid. Atom abstraction from excoyclic postitons of derivatives of methylated pyridines and quinolines: An evaluation of change separation in the transition states of these reactions. 1989.

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Book chapters on the topic "Quinoline derivative"

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Paulus, Wilfried. "Pyridine Derivatives and Related Compounds (Benzopyridines = Quinolines)." In Microbicides for the Protection of Materials. Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-011-2118-7_13.

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Paulus, Wilfried. "Pyridine Derivatives and Related Compounds (Benzopyridines = Quinolines)." In Directory of Microbicides for the Protection of Materials. Springer Netherlands, 2004. http://dx.doi.org/10.1007/1-4020-2818-0_36.

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Desai, N. C., and Amit M. Dodiya. "Microwave-Induced Synthesis of Various Quinoline Derivatives: Green Methodologies in Organic Synthesis." In Green Chemistry: Synthesis of Bioactive Heterocycles. Springer India, 2014. http://dx.doi.org/10.1007/978-81-322-1850-0_6.

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Ruckdeschel, G., W. Ehret, and A. Ahl. "Susceptibility of Legionella spp. to Quinolone Derivatives and Related Organic Acids." In Ciprofloxacin. Vieweg+Teubner Verlag, 1986. http://dx.doi.org/10.1007/978-3-663-01930-5_12.

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Sun, Xiao Hui, Jian Qing Guan, Jian Jun Tan, Chang Liu, and Cun Xin Wang. "Exploring Quinoline Ring Derivatives as Potent Integrase Inhibitors Using Ligand-based Modeling Studies." In IFMBE Proceedings. Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-29305-4_334.

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Kokotos, G., C. Tzougraki, and R. Geiger. "SENSITIVE CHYMOTRYPSIN DETERMINATION USING FLUOROGENIC SUBSTRATES CONTAINING 2-QUINOLINONE DERIVATIVES." In Porto Carras, Chalkidiki, Greece, Aug. 31–Sept. 5, 1986, edited by Dimitrios Theodoropoulos. De Gruyter, 1987. http://dx.doi.org/10.1515/9783110864243-142.

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Gasser, T. C., E. H. Larsen, T. Dørflinger, and P. O. Madsen. "The Influence of Various Body Fluids and pH on E. Coli MIC of Quinolone Derivatives." In Fortschritte der Urologie und Nephrologie. Steinkopff, 1992. http://dx.doi.org/10.1007/978-3-642-85422-4_9.

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Hoogkamp-Korstanje, J. A. A. "Comparative in Vitro Activity of Five Quinoline Derivatives and Five Other Antimicrobial Agents Used in Oral Therapy." In Ciprofloxacin. Vieweg+Teubner Verlag, 1986. http://dx.doi.org/10.1007/978-3-663-01930-5_2.

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Netter, K. J., B. Hahnemann, S. A. Mangoura, et al. "Selective Inducers of the Coh-Locus Enhance the Metabolisms of Coumarin- and of Quinoline-Derivatives but Not That of Naphthalenes." In Advances in Experimental Medicine and Biology. Springer New York, 1991. http://dx.doi.org/10.1007/978-1-4684-5877-0_46.

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Singh Thakur, Gajendra, Ajay Kumar Gupta, and Dr Sanmati Kumar Jain. "SYNTHESIS OF QUINOLINE AND ITS DERIVATIVES USING VARIOUS NAME REACTIONS: AN OVERVIEW." In Futuristic Trends in Chemical Material Sciences & Nano Technology Volume 3 Book 12. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/v3becs12p2ch8.

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Quinolines are a significant class of heterocyclic compounds and an essential component of natural alkaloids. They exhibit a broad range of biological and therapeutic actions. In order to efficiently synthesize quinoline and its derivatives, researchers and scientists have been paying close attention to the development of quinoline synthetic methods in recent years. This review summarizes the development of quinoline synthesis by numerous name reactions with reaction mechanisms and the application of synthesis techniques for quinolines and their derivatives, which develops innovative ideas and
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Conference papers on the topic "Quinoline derivative"

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Lukovits, I., T. Kosztolányi, E. Kálmán, and G. Pálinkás. "Corrosion Inhibitors: Correlation between Chemical Structure and Efficiency." In CORROSION 1999. NACE International, 1999. https://doi.org/10.5006/c1999-99242.

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Abstract Corrosion inhibition efficiencies of heterocyclic, aromatic or partially saturated aromatic compounds (pyrimidines, benzothiazole derivatives, amino-acids containing an aromatic part, pyridines and quinolines) were correlated with quantum chemical indices of the respective molecules. Inhibition efficiencies measured in acidic solutions containing 0.001 and 0.01 mol/L of the inhibitor, respectively, were collected. The quantum chemical calculations were done by using the simple Hückel method. Comparison of inhibition efficiencies and the differences between energies of the highest occu
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Yang, Zhen, Yefei Wang, Matjaž Finšgar, Jiajia Wu, and Wengang Ding. "Novel High-Efficient Key Component of Steel Corrosion Inhibitors Formulation for Acidification: Indolizine Derivatives of the Conventional N-Heterocyclic Quaternary Ammonium Salts." In SPE International Conference on Oilfield Chemistry. SPE, 2023. http://dx.doi.org/10.2118/213814-ms.

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Abstract Acidizing, the widely used technique for well stimulation, requires a great consumption of effective Corrosion Inhibitors (CIs), due to the severe and fast corrosion of metallic equipment caused by strong hot acid as soon as the acidizing fluids are pumping down to reservoir. This paper presents a new concept of indolizine derivative inhibitors with remarkable inhibition effectiveness for steel under acidizing condition, which will reduce the cost and environmental burden of acidizing CIs significantly. Indolizine derivatives of several quinolinium salts (serves as main component of c
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Sousa, Rui P. C. L., Susana P. G. Costa, Rita B. Figueira, and M. Manuela M. Raposo. "Quinoline-Based Hydrazone Derivative as a Biocide Chemosensor: Synthesis and Sensing Studies." In ECSA-9. MDPI, 2022. http://dx.doi.org/10.3390/ecsa-9-13199.

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Bassissi, Firas, Elena Patricia Gifu, Sonia Brun, et al. "Abstract 1914: GNS561 is a new quinoline derivative with high efficacy on cancer stem cells from colorectal liver metastasis and hepatocellular carcinoma." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-1914.

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Daoud, Djamel, Tahar Douadi, Hanane Hamani, Djillali Ghobrini, and Kamal Aiboud. "Experimental and theoretical study of a new synthesized Quinoline derivative as Greene inhibitor of corrosion for the cooling circuits in desalinated water." In 2015 3rd International Conference on Control, Engineering & Information Technology (CEIT). IEEE, 2015. http://dx.doi.org/10.1109/ceit.2015.7233032.

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BASSISSI, Firas, Zuzana Macek Jilkova, Sonia Brun, et al. "Abstract 5124: GNS561 a new quinoline derivative inhibits the growth of hepatocellular carcinoma in a cirrhotic rat and human PDX orthotopic mouse models." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-5124.

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Musiol, Robert, Josef Jampilek, Katarina Kralova, et al. "New Quinoline Derivatives Possessing Herbicidal Activity." In The 9th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2005. http://dx.doi.org/10.3390/ecsoc-9-01508.

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Zbancioc, Gheorghita, Costel Moldoveanu, and Ionel I. Mangalagiu. "Syntheses of new benzoquinoline derivatives with anticancer activity." In Conferința științifică națională cu participare internațională "Integrare prin cercetare și inovare", dedicată Zilei Internaționale a Științei pentru Pace și Dezvoltare. Moldova State University, 2025. https://doi.org/10.59295/spd2024n.92.

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This work synthesized various novel benzo[c]quinoline compounds, detailed their structural features, and examined their anticancer activity in vitro. First, the nitrogen atom in benzo[c]quinoline is quaternized, and the in situ-formed ylide is then subjected to a [3+2] dipolar cycloaddition reaction. A detailed investigation was conducted to determine how successful traditional thermal heating (TH) synthesis was in comparison to microwave (MW) and ultrasonic (US) irradiation. FTIR, HRMS, and NMR were the three spectral techniques that were used to prove the structure of all the obtained compou
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Ustinov, Ilya, Nikolaj Khlytin, Yurij Atroshchenko, and Irina Shahkeldyan. "NEW THIAZOL DERIVATIVES CONTAINING NITRO QUINOLINE FRAGMENT." In Chemistry of nitro compounds and related nitrogen-oxygen systems. LLC MAKS Press, 2019. http://dx.doi.org/10.29003/m797.aks-2019/383-384.

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Mangalagiu, Violeta, Dorina Amariucai-Mantu, Vasilichia Antoci, Dumitrela Diaconu, and Ionel I. Mangalagiu. "Azine derivatives with antimicrobial properties." In Conferința științifică națională cu participare internațională "Integrare prin cercetare și inovare", dedicată Zilei Internaționale a Științei pentru Pace și Dezvoltare. Moldova State University, 2025. https://doi.org/10.59295/spd2024n.87.

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Abstract:
Azine derivatives, especially pyridine, quinoline and their fused derivatives, are invaluable scaffolds in medicinal chemistry having a large variety of biological activities, antimicrobials including. In this work we present some recent results that we obtained in the field of azine with antibacterial, antifungal and antituberculosis activity. Some of the obtained results are very promising, the antimicrobial activity of some azine derivatives being spectacular.
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